Author: "Martorelli, G." - Searchworks@Jio Institute Digital Library Search Results

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19 results on '"Martorelli, G."'

1. Abdominal drainage after elective colorectal surgery: propensity score-matched retrospective analysis of an Italian cohort

Author: Guadagni, S, Catarci, M, Masedu, F, Karim, M, Clementi, M, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Scatizzi, M, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Campagnacci, R, De Luca, R, Ficari, F, Sica, G, Scabini, S, Liverani, A, Caricato, M, Patriti, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Guercioni, G, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Ciano, P, Benedetti, M, Montemurro, L, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Pandolfini, L, Falsetto, A, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Maurizi, A, Simone, M, Giudici, F, Cianchi, F, Sensi, B, Aprile, A, Soriero, D, Scarinci, A, Capolupo, G, Sisti, V, Ricci, M, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Cicconi, S, Marziali, I, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Guadagni S., Catarci M., Masedu F., Karim M. E., Clementi M., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Scatizzi M., Pirozzi F., Delrio P., Garulli G., Marini P., Campagnacci R., De Luca R., Ficari F., Sica G., Scabini S., Liverani A., Caricato M., Patriti A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Guercioni G., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Ciano P., Benedetti M., Montemurro L. A., Mattei M. S., Belloni E., Apa D., Di Carlo M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Pandolfini L., Falsetto A., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Maurizi A., Simone M., Giudici F., Cianchi F., Sensi B., Aprile A., Soriero D., Scarinci A., Capolupo G. T., Sisti V., Ricci M. L., Sagnotta A., Molfino S., Amodio P., Cardinali A., Cicconi S., Marziali I., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., La Gioia G., Guadagni, S, Catarci, M, Masedu, F, Karim, M, Clementi, M, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Scatizzi, M, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Campagnacci, R, De Luca, R, Ficari, F, Sica, G, Scabini, S, Liverani, A, Caricato, M, Patriti, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Guercioni, G, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Ciano, P, Benedetti, M, Montemurro, L, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Pandolfini, L, Falsetto, A, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Maurizi, A, Simone, M, Giudici, F, Cianchi, F, Sensi, B, Aprile, A, Soriero, D, Scarinci, A, Capolupo, G, Sisti, V, Ricci, M, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Cicconi, S, Marziali, I, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Guadagni S., Catarci M., Masedu F., Karim M. E., Clementi M., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Scatizzi M., Pirozzi F., Delrio P., Garulli G., Marini P., Campagnacci R., De Luca R., Ficari F., Sica G., Scabini S., Liverani A., Caricato M., Patriti A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Guercioni G., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Ciano P., Benedetti M., Montemurro L. A., Mattei M. S., Belloni E., Apa D., Di Carlo M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Pandolfini L., Falsetto A., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Maurizi A., Simone M., Giudici F., Cianchi F., Sensi B., Aprile A., Soriero D., Scarinci A., Capolupo G. T., Sisti V., Ricci M. L., Sagnotta A., Molfino S., Amodio P., Cardinali A., Cicconi S., Marziali I., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., and La Gioia G.
Abstract: Background: In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim of this study was to evaluate the impact of abdominal drain placement on early adverse events in patients undergoing elective colorectal surgery. Methods: A database was retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. The primary endpoint was the postoperative duration of stay, and the secondary endpoints were surgical site infections, infectious morbidity rate defined as surgical site infections plus pulmonary infections plus urinary infections, anastomotic leakage, overall morbidity rate, major morbidity rate, reoperation and mortality rates. The results of multiple logistic regression analyses were presented as odds ratios (OR) and 95 per cent c.i. Results: A total of 6157 patients were analysed to produce two well-balanced groups of 1802 patients: group (A), no abdominal drain(s) and group (B), abdominal drain(s). Group A versus group B showed a significantly lower risk of postoperative duration of stay >6 days (OR 0.60; 95 per cent c.i. 0.51–0.70; P < 0.001). A mean postoperative duration of stay difference of 0.86 days was detected between groups. No difference was recorded between the two groups for all the other endpoints. Conclusion: This study confirms that placement of abdominal drain(s) after elective colorectal surgery is associated with a non-clinically significant longer (0.86 days) postoperative duration of stay but has no impact on any other secondary outcomes, confirming that abdominal drains should not be used routinely in colorectal surgery.
Published: 2024

2. Mechanical bowel preparation in elective colorectal surgery: a propensity score-matched analysis of the Italian colorectal anastomotic leakage (iCral) study group prospective cohorts

Author: Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Patriti, A, Campagnacci, R, Sica, G, Caricato, M, Montemurro, L, Ciano, P, Benedetti, M, Guercioni, G, Scatizzi, M, De Luca, R, Ficari, F, Scabini, S, Liverani, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Cicconi, S, Marziali, I, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Sisti, V, Ricci, M, Maurizi, A, Sensi, B, Capolupo, G, Pandolfini, L, Falsetto, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Aprile, A, Soriero, D, Scarinci, A, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Pirozzi F., Delrio P., Garulli G., Marini P., Patriti A., Campagnacci R., Sica G., Caricato M., Montemurro L. A., Ciano P., Benedetti M., Guercioni G., Scatizzi M., De Luca R., Ficari F., Scabini S., Liverani A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Mattei M. S., Belloni E., Apa D., Di Carlo M., Cicconi S., Marziali I., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Sisti V., Ricci M. L., Maurizi A., Sensi B., Capolupo G. T., Pandolfini L., Falsetto A., Simone M., Giudici F., Cianchi F., Baldini G., Aprile A., Soriero D., Scarinci A., Sagnotta A., Molfino S., Amodio P., Cardinali A., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., La Gioia G., Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Patriti, A, Campagnacci, R, Sica, G, Caricato, M, Montemurro, L, Ciano, P, Benedetti, M, Guercioni, G, Scatizzi, M, De Luca, R, Ficari, F, Scabini, S, Liverani, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Cicconi, S, Marziali, I, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Sisti, V, Ricci, M, Maurizi, A, Sensi, B, Capolupo, G, Pandolfini, L, Falsetto, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Aprile, A, Soriero, D, Scarinci, A, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Pirozzi F., Delrio P., Garulli G., Marini P., Patriti A., Campagnacci R., Sica G., Caricato M., Montemurro L. A., Ciano P., Benedetti M., Guercioni G., Scatizzi M., De Luca R., Ficari F., Scabini S., Liverani A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Mattei M. S., Belloni E., Apa D., Di Carlo M., Cicconi S., Marziali I., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Sisti V., Ricci M. L., Maurizi A., Sensi B., Capolupo G. T., Pandolfini L., Falsetto A., Simone M., Giudici F., Cianchi F., Baldini G., Aprile A., Soriero D., Scarinci A., Sagnotta A., Molfino S., Amodio P., Cardinali A., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., and La Gioia G.
Abstract: Retrospective evaluation of the effects of mechanical bowel preparation (MBP) on data derived from two prospective open-label observational multicenter studies in Italy regarding elective colorectal surgery. MBP for elective colorectal surgery remains a controversial issue with contrasting recommendations in current guidelines. The Italian ColoRectal Anastomotic Leakage (iCral) study group, therefore, decided to estimate the effects of no MBP (treatment variable) versus MBP for elective colorectal surgery. A total of 8359 patients who underwent colorectal resection with anastomosis were enrolled in two consecutive prospective studies in 78 surgical centers in Italy from January 2019 to September 2021. A retrospective PSMA was performed on 5455 (65.3%) cases after the application of explicit exclusion criteria to eliminate confounders. The primary endpoints were anastomotic leakage (AL) and surgical site infections (SSI) rates; the secondary endpoints included SSI subgroups, overall and major morbidity, reoperation, and mortality rates. Overall length of postoperative hospital stay (LOS) was also considered. Two well-balanced groups of 1125 patients each were generated: group A (No MBP, true population of interest), and group B (MBP, control population), performing a PSMA considering 21 covariates. Group A vs. group B resulted significantly associated with a lower risk of AL [42 (3.5%) vs. 73 (6.0%) events; OR 0.57; 95% CI 0.38–0.84; p = 0.005]. No difference was recorded between the two groups for SSI [73 (6.0%) vs. 85 (7.0%) events; OR 0.88; 95% CI 0.63–1.22; p = 0.441]. Regarding the secondary endpoints, no MBP resulted significantly associated with a lower risk of reoperation and LOS > 6 days. This study confirms that no MBP before elective colorectal surgery is significantly associated with a lower risk of AL, reoperation rate, and LOS < 6 days when compared with MBP.
Published: 2024

3. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author: Alagna, V., Amodio, P., Anania, G., Angeloni, R., Arici, E., Baiocchi, G., Baraghini, M., Benedetti, M., Bertocchi, E., Borghi, F., Brisinda, G., Campagnacci, R., Capolupo, G.T., Caricato, M., Carrara, A., Ceccaroni, M., Chiarello, M.M., Cianflocca, D., Ciano, P., Cicconi, S., Clementi, M., Delrio, P., Di Cesare, T., Di Marco, C., Falsetto, A., Garulli, G., Guadagni, S., Guercioni, G., Lambertini, M., Liverani, A., Longo, G., Lucchi, A., Luzzi, A.P., Macarone Palmieri, R., Mancini, S., Marini, P., Marsanic, P., Martino, A., Martorelli, G., Marziali, I., Maurizi, A., Migliore, M., Molfino, S., Motter, M., Muratore, A., Pace, U., Pandolfini, L., Pavanello, M., Pirozzi, F., Ruffo, G., Ruggeri, B., Sagnotta, A., Santoni, S., Scabini, S., Scatizzi, M., Sciuto, A., Sica, G., Tirone, G., Tomassini, F., Vettoretto, N., Zigiotto, D., Guerra, Francesco, Petrelli, Filippo, Greco, Paola Antonella, Sisti, Valerio, Catarci, Marco, Montalti, Roberto, and Patriti, Alberto
Published: 2021
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4. Three-row versus two-row circular staplers for left-sided colorectal anastomosis: a propensity score-matched analysis of the iCral 2 and 3 prospective cohorts

Author: Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Scatizzi, M, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Campagnacci, R, De Luca, R, Ficari, F, Sica, G, Scabini, S, Liverani, A, Caricato, M, Patriti, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Guercioni, G, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Ciano, P, Benedetti, M, Montemurro, L, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Pandolfini, L, Falsetto, A, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Maurizi, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Sensi, B, Aprile, A, Soriero, D, Scarinci, A, Capolupo, G, Sisti, V, Ricci, M, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Cicconi, S, Marziali, I, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Scatizzi M., Pirozzi F., Delrio P., Garulli G., Marini P., Campagnacci R., De Luca R., Ficari F., Sica G., Scabini S., Liverani A., Caricato M., Patriti A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Guercioni G., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Ciano P., Benedetti M., Montemurro L. A., Mattei M. S., Belloni E., Apa D., Di Carlo M., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Pandolfini L., Falsetto A., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Maurizi A., Simone M., Giudici F., Cianchi F., Baldini G., Sensi B., Aprile A., Soriero D., Scarinci A., Capolupo G. T., Sisti V., Ricci M. L., Sagnotta A., Molfino S., Amodio P., Cardinali A., Cicconi S., Marziali I., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., La Gioia G., Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Scatizzi, M, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Campagnacci, R, De Luca, R, Ficari, F, Sica, G, Scabini, S, Liverani, A, Caricato, M, Patriti, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Guercioni, G, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Ciano, P, Benedetti, M, Montemurro, L, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Pandolfini, L, Falsetto, A, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Maurizi, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Sensi, B, Aprile, A, Soriero, D, Scarinci, A, Capolupo, G, Sisti, V, Ricci, M, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Cicconi, S, Marziali, I, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Scatizzi M., Pirozzi F., Delrio P., Garulli G., Marini P., Campagnacci R., De Luca R., Ficari F., Sica G., Scabini S., Liverani A., Caricato M., Patriti A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Guercioni G., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Ciano P., Benedetti M., Montemurro L. A., Mattei M. S., Belloni E., Apa D., Di Carlo M., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Pandolfini L., Falsetto A., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Maurizi A., Simone M., Giudici F., Cianchi F., Baldini G., Sensi B., Aprile A., Soriero D., Scarinci A., Capolupo G. T., Sisti V., Ricci M. L., Sagnotta A., Molfino S., Amodio P., Cardinali A., Cicconi S., Marziali I., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., and La Gioia G.
Abstract: Background: Since most anastomoses after left-sided colorectal resections are performed with a circular stapler, any technological change in stapling devices may influence the incidence of anastomotic adverse events. The aim of the present study was to analyze the effect of a three-row circular stapler on anastomotic leakage and related morbidity after left-sided colorectal resections. Materials and methods: A circular stapled anastomosis was performed in 4255 (50.9%) out of 8359 patients enrolled in two prospective multicenter studies in Italy, and, after exclusion criteria to reduce heterogeneity, 2799 (65.8%) cases were retrospectively analyzed through a 1:1 propensity score-matching model including 20 covariates relative to patient characteristics, to surgery and to perioperative management. Two well-balanced groups of 425 patients each were obtained: group (A) – true population of interest, anastomosis performed with a three-row circular stapler; group (B) – control population, anastomosis performed with a two-row circular stapler. The target of inferences was the average treatment effect in the treated (ATT). The primary endpoints were overall and major anastomotic leakage and overall anastomotic bleeding; the secondary endpoints were overall and major morbidity and mortality rates. The results of multiple logistic regression analyses for the outcomes, including the 20 covariates selected for matching, were presented as odds ratios (OR) and 95% confidence intervals (95% CI). Results: Group A versus group B showed a significantly lower risk of overall anastomotic leakage (2.1 vs. 6.1%; OR 0.33; 95% CI 0.15–0.73; P = 0.006), major anastomotic leakage (2.1 vs. 5.2%; OR 0.39; 95% CI 0.17–0.87; P = 0.022), and major morbidity (3.5 vs. 6.6% events; OR 0.47; 95% CI 0.24–0.91; P = 0.026). Conclusion: The use of three-row circular staplers independently reduced the risk of anastomotic leakage and related morbidity after left-sided colorectal resection. Twenty-five pati
Published: 2023

5. ERAS program adherence-institutionalization, major morbidity and anastomotic leakage after elective colorectal surgery: the iCral2 multicenter prospective study

Author: Catarci, M, Ruffo, G, Viola, M, Pirozzi, F, Delrio, P, Borghi, F, Garulli, G, Baldazzi, G, Marini, P, Sica, G, Guercioni, G, Ciano, P, Benedetti, M, Cicconi, S, Marziali, I, Bertocchi, E, Altamura, A, Rubichi, F, Sciuto, A, Pace, U, Fares Bucci, A, Cianflocca, D, Migliore, M, Pirrera, B, Alagna, V, Cassini, D, Attinà, G, Arcudi, C, Sensi, B, Bucci, A, Campagnacci, R, Maurizi, A, Basti, M, Frazzini, D, Caracino, V, Pedrazzani, C, Turri, G, Mancini, S, Sagnotta, A, Scatizzi, M, Pandolfini, L, Falsetto, A, Baiocchi, G, Molfino, S, Totis, M, Braga, M, Liverani, A, Cesare, T, Scabini, S, Martino, A, Luca, R, Simone, M, Carrara, A, Tirone, G, Motter, M, Caricato, M, Capolupo, G, Amodio, P, Palmieri, R, Pavanello, M, Marco, C, Muratore, A, Marsanic, P, Patriti, A, Sisti, V, Lucchi, A, Martorelli, G, Clementi, M, Guadagni, S, Longo, G, Tomassini, F, Santoni, S, Vettoretto, N, Botteri, E, Armellini, A, Brisinda, G, Chiarello, M, Cariati, M, Berti, S, Gennai, A, Anania, G, Rubino, S, Siquini, W, Cardinali, A, Catarci M., Ruffo G., Viola M. G., Pirozzi F., Delrio P., Borghi F., Garulli G., Baldazzi G., Marini P., Sica G., Guercioni G., Ciano P., Benedetti M., Cicconi S., Marziali I., Bertocchi E., Altamura A., Rubichi F., Sciuto A., Pace U., Fares Bucci A., Cianflocca D., Migliore M., Pirrera B., Alagna V., Cassini D., Attinà G. M., Arcudi C., Sensi B., Bucci A. F., Campagnacci R., Maurizi A., Basti M., Frazzini D., Caracino V., Pedrazzani C., Turri G., Mancini S., Sagnotta A., Scatizzi M., Pandolfini L., Falsetto A., Baiocchi G. L., Molfino S., Totis M., Braga M., Liverani A., Cesare T. D., Scabini S., Martino A., Luca R. D., Simone M., Carrara A., Tirone G., Motter M., Caricato M., Capolupo G. T., Amodio P., Palmieri R. M., Pavanello M., Marco C. D., Muratore A., Marsanic P., Patriti A., Sisti V., Lucchi A., Martorelli G., Clementi M., Guadagni S., Longo G., Tomassini F., Santoni S., Vettoretto N., Botteri E., Armellini A., Brisinda G., Chiarello M. M., Cariati M., Berti S., Gennai A., Anania G., Rubino S., Siquini W., Cardinali A., Catarci, M, Ruffo, G, Viola, M, Pirozzi, F, Delrio, P, Borghi, F, Garulli, G, Baldazzi, G, Marini, P, Sica, G, Guercioni, G, Ciano, P, Benedetti, M, Cicconi, S, Marziali, I, Bertocchi, E, Altamura, A, Rubichi, F, Sciuto, A, Pace, U, Fares Bucci, A, Cianflocca, D, Migliore, M, Pirrera, B, Alagna, V, Cassini, D, Attinà, G, Arcudi, C, Sensi, B, Bucci, A, Campagnacci, R, Maurizi, A, Basti, M, Frazzini, D, Caracino, V, Pedrazzani, C, Turri, G, Mancini, S, Sagnotta, A, Scatizzi, M, Pandolfini, L, Falsetto, A, Baiocchi, G, Molfino, S, Totis, M, Braga, M, Liverani, A, Cesare, T, Scabini, S, Martino, A, Luca, R, Simone, M, Carrara, A, Tirone, G, Motter, M, Caricato, M, Capolupo, G, Amodio, P, Palmieri, R, Pavanello, M, Marco, C, Muratore, A, Marsanic, P, Patriti, A, Sisti, V, Lucchi, A, Martorelli, G, Clementi, M, Guadagni, S, Longo, G, Tomassini, F, Santoni, S, Vettoretto, N, Botteri, E, Armellini, A, Brisinda, G, Chiarello, M, Cariati, M, Berti, S, Gennai, A, Anania, G, Rubino, S, Siquini, W, Cardinali, A, Catarci M., Ruffo G., Viola M. G., Pirozzi F., Delrio P., Borghi F., Garulli G., Baldazzi G., Marini P., Sica G., Guercioni G., Ciano P., Benedetti M., Cicconi S., Marziali I., Bertocchi E., Altamura A., Rubichi F., Sciuto A., Pace U., Fares Bucci A., Cianflocca D., Migliore M., Pirrera B., Alagna V., Cassini D., Attinà G. M., Arcudi C., Sensi B., Bucci A. F., Campagnacci R., Maurizi A., Basti M., Frazzini D., Caracino V., Pedrazzani C., Turri G., Mancini S., Sagnotta A., Scatizzi M., Pandolfini L., Falsetto A., Baiocchi G. L., Molfino S., Totis M., Braga M., Liverani A., Cesare T. D., Scabini S., Martino A., Luca R. D., Simone M., Carrara A., Tirone G., Motter M., Caricato M., Capolupo G. T., Amodio P., Palmieri R. M., Pavanello M., Marco C. D., Muratore A., Marsanic P., Patriti A., Sisti V., Lucchi A., Martorelli G., Clementi M., Guadagni S., Longo G., Tomassini F., Santoni S., Vettoretto N., Botteri E., Armellini A., Brisinda G., Chiarello M. M., Cariati M., Berti S., Gennai A., Anania G., Rubino S., Siquini W., and Cardinali A.
Abstract: Background: Enhanced recovery after surgery (ERAS) programs influence morbidity rates and length of stay after colorectal surgery (CRS), and may also impact major complications and anastomotic leakage rates. A prospective multicenter observational study to investigate the interactions between ERAS program adherence and early outcomes after elective CRS was carried out. Methods: Prospective enrolment of patients submitted to elective CRS with anastomosis in 18 months. Adherence to 21 items of ERAS program was measured upon explicit criteria in every case. After univariate analysis, independent predictors of primary endpoints [major morbidity (MM) and anastomotic leakage (AL) rates] were identified through logistic regression analyses including all significant variables, presenting odds ratios (OR). Results: Institutional ERAS protocol was declared by 27 out of 38 (71.0%) participating centers. Median overall adherence to ERAS program items was 71.4%. Among 3830 patients included in the study, MM and AL rates were 4.7% and 4.2%, respectively. MM rates were independently influenced by intra- and/or postoperative blood transfusions (OR 7.79, 95% CI 5.46–11.10; p < 0.0001) and standard anesthesia protocol (OR 0.68, 95% CI 0.48–0.96; p = 0.028). AL rates were independently influenced by male gender (OR 1.48, 95% CI 1.06–2.07; p = 0.021), intra- and/or postoperative blood transfusions (OR 4.29, 95% CI 2.93–6.50; p < 0.0001) and non-standard resections (OR 1.49, 95% CI 1.01–2.22; p = 0.049). Conclusions: This study disclosed wide room for improvement in compliance to several ERAS program items. It failed to detect any significant association between institutionalization and/or adherence rates to ERAS program with primary endpoints. These outcomes were independently influenced by gender, intra- and postoperative blood transfusions, non-standard resections, and standard anesthesia protocol.
Published: 2022

6. Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Author: Nepogodiev, D., Matthews, J. H., Morley, G. L., Naumann, D. N., Ball, A., Chauhan, P., Bhanderi, S., Mohamed, I., Glasbey, J. C., Wilkin, R. J. W., Drake, T. M., Clements, J., Blencowe, N. S., Herrod, P. J. J., Pata, F., Frasson, M., Blanco-Colino, R., Soares, A. S., Nepogodiev D, Bhangu A., Matthews, Jh, Morley, Gl, Naumann, Dn, Ball, A, Chauhan, P, Bhanderi, S, Mohamed, I, Glasbey, Jc, Wilkin, R, Drake, Tm, Clements, J, Blencowe, Ns, Herrod, P, Pata, F, Frasson, M, Blanco-Colino, R, Soares, As, Bhangu, A, Nepogodiev, D, Jain, S, Amuthalingam, T, Tyler, R, Griffiths, Ea, Pinkney, Td, Gee, O, Morton, Dg, Beggs, A, Beral, D, Bowley, D, Cruickshank, N, Daniels, I, Griffiths, E, Hornby, St, Lund, Jn, Marriott, P, Singh, P, Smart, Nj, Speake, D, Thompson, C, Torkington, J, Torrance, A, Vohra, R, Warren, O, Winter, Dc, Pellino, G, Sgrò, A, Simioni, A, Farina, V, Podda, M, Di Saverio, S, Birindelli, A, Pasquali, S, Itsurg, Surg, Pt, Bolton, W, Bradshaw, Cj, Chean, Cs, Harris, G, Haddow, Jb, Jamieson, Nb, Mccain, S, Mason, J, Milgrom, D, Nana, Gr, Mohamed, Mn, Brien, Jo, Pearce, J, Rabie, M, Sahnan, K, Sarmah, P, Skerritt, C, Ghazanfar, Ma, Sreedharan, L, Kabwama, S, Gray, Rt, Kamande, Iw, Nazarian, S, Dar, Fa, Misky, At, Arunachalam, S, Twum-Barima, Cs, Mohamed, Im, Connor, Kl, Coe, Po, Kosti, A, Elshaer, M, Colvin, Da, Charalambous, Mp, Yeung, K, Merker, L, Morrison, T, Thaventhiran, Aj, Gilbert, Tm, Clements, Jm, Hicks, G, Afshar, S, Mckinley, Nc, Assaf, N, Hanna, T, Macinnes, E, Thavanesan, N, Dubois, As, Palani-Velu, Lk, Tezas, S, Yow, L, Radwan, Rw, Abdelrahman, M, Lee, Ka, Zarka, Za, Mcdowall, Na, Tan, Cy, Venn, Ml, Ashmore, Dl, Whitehorn, Se, Golder, Am, Reddy, A, Delimpalta, C, Kay, Oh, Shah, Sm, Eiben, I, Doyle, C, Tudyka, V, Issa, E, West, H, Brewer, Hk, Farrow, Ez, Taylor, Ns, Smart, Cj, Griffiths, Np, Halkias, C, Vitish-Sharma, P, Knight, Sr, Mowbray, Ng, Olivier, Jb, Lee, Kj, Clement, Kd, Chrastek, D, Panda, N, Connor, Mj, Fahmy, Se, Bryan, Es, Ngu, Ws, Adegbola, So, Vaughan, Em, Stupalkowska, W, Simmonds, L, Malik, A, Hussein, A, Karim, Mj, Singhal, T, Ormiston, R, Kung, V, Rabie, Ma, Park, Jh, Lal, N, Worku, D, D'Auria, M, Ang, A, Orizu, M, Gammeri, E, Clough, E, Choy, Ch, Lawday, S, Hann, Aj, Robinson, D, Wardle, Bg, Mcdonnell, D, Rutherford, Dg, Hickey, Lm, Garg, Ag, Rezvani, S, Bell, Cr, Mahmood, F, Rehman, S, Donaldson, G, Peleki, A, Pearce, L, Sharp, Ol, Singh, S, Thompson, Db, El-Tayar, O, Hollyman, M, Rupasinghe, Sn, Toomey, Db, Murray, Mp, Amtul, N, Mersh, Rj, Newton, Rc, Al-Khyatt, W, Stephens, Gf, Abbas, Sh, Iqbal, Mr, Brown, Ce, Renshaw, S, Hureibi, Ka, Pullabatla-Venkata, Up, Donohoe, No, Myatt, A, Egan, Rj, Rangarajan, K, Trail, M, Mckay, Sc, Engall, N, Jerome, E, Townsend, Dc, Patel, By, Pronin, S, Chandratreya, N, Choong, Jh, Mohamed, Tm, Hudson-Peacock, Nj, Manson, R, Hebbar, K, Mothe, Bs, Weegenaar, Cr, Saad, M, Bowman, Cr, Serventi, F, Fleres, F, Foppa, C, Pata, G, Baronio, G, Pertile, D, Lucchi, A, Sagnotta, A, Maretto, I, Campagnaro, T, Gatti, M, Gjoni, E, Roscio, F, Inama, M, Coccolini, F, Colombo, F, Avanzolini, A, Aresu, S, De-Manzoni-Garberini, A, Merlini, Da, Chessa, A, Tamini, N, Mulas, S, Cillara, N, Coletta, D, Atzeni, J, Erdas, E, Gallo, G, Francone, E, Di Gioia, P, Bianchi, Cl, Ferrara, F, Biancafarina, A, Scabini, S, Marano, L, Miegge, A, Sasia, D, Savino, G, Scatizzi, M, D'Amico, Fe, Arcuri, Ga, Gavagna, L, Salamone, G, Tatulli, F, Goldin, E, Matos, Ml, Caldeira, Ab, Romano, J, Pereira, J, Azevedo, J, Azevedo, Jm, Simoes, J, Silva, A, O'Leary, Dp, Kennedy, Nd, Quinn, Em, Zhang, Ay, Neary, Pm, De-Marchi, Ja, O'Connor, Br, Wijesundera, K, Foley, Nm, Wong, J, Tiedt, La, Bolger, Jc, Connelly, Tm, Ahmed, Os, Vigorita, V, García, V, Arredondo, J, Redondo, E, Sainz, B, Aldrey, I, Landaluce-Olavarria, A, Gómez, Aa, Cordoba, E, Sánchez-Fuentes, Mn, Cerdán-Santacruz, C, Beltran-De-Heredia, J, García, M, Veres, T, García-Novoa, A, Abellán, Am, García-Catalá, L, Ruiz-Marín, M, Menendez, P, Roldán-Ortiz, S, Navas-Cuéllar, Ja, Sabia, D, Gomez-Rosado, Jc, Navidad, Ms, Caula, C, Sanchez, Er, Espin-Basany, E, Fernández-Martínez, D, Bravo-Gutiérrez, Af, Payá-Llorente, C, Dujovne, P, Lima, F, Soria-Aledo, V, Gomez, Cj, Pascual-Miguelañez, I, Muinelo, M, Alvarez, Cm, Vargas-Pierola, Hj, Vallve-Bernal, M, Hidalgo-Rosas, Jm, Arenal-Vera, Jj, Sena-Ruiz, F, Sanchez-Guillen, L, Villarejo-Campos, P, Tallon-Aguilar, L, Garcea, A, Bennett, Jm, Whittaker, L, Gidwani, Al, Byrnes, Ck, Saunders, S, Shiwani, Mh, Ashraf, N, Venkatasubramaniam, Ak, Bevan, Ke, Mcarthur, D, Mustafa, Ak, Griffith, Jp, Blazeby, Jm, Charalabopoulos, A, Campbell, W, Reese, G, Warren, Oj, Peacock, M, Menzies, D, Jenner, D, Eardley, Nj, Yoong, S, Abulafi, M, Avalapati, H, Thompson, R, Nastro, P, Kochupapy, R, Stubbs, Bm, Mcintyre, R, Crozier, J, Patel, Pk, Pento, V, Beasley, Wd, Roxburgh, C, Youssef, H, Alexander, R, Denley, S, Di Franco, F, Quddus, A, Saha, A, Hunter, I, Hannay, J, Velchuru, Vr, Bond-Smith, G, Salama, Y, Bhargava, A, Panagiotopoulos, Sp, Watson, N, Garcea, G, Boddy, Ap, Dunning, Pg, Lloyd, G, Gurjar, Sv, Hill, J, Andrews, B, Singh, A, Ruzvidzo, F, Shingler, G, Mahon, D, Elgaddal, S, Payne, Cj, Shaikh, Ia, Dalmia, S, Nair, Ms, Finch, Jg, Chapple, Ks, Bawa, S, Watfah, J, Carden, Ca, Makhija, R, Rao, M, Sarveswaran, J, Vijay, V, Rekhraj, S, Knight, B, Siddiqui, Mn, Sebastian, Jf, Glen, P, Vakis, S, Ebied, H, Rajaram, R, Gray, J, Mcgrath, D, Faulkner, G, Gopalswamy, S, Varcada, M, Woodward, A, Williams, Gl, Szentpali, K, Ravindran, R, Bronder, C, Thaha, Ma, Rate, A, Shetty, Vd, Rao, V, Sajid, Ms, Clements, B, Patel, Rt, Mason, C, Branagan, G, Maude, K, Kaur, G, Lyons, A, Ainsworth, P, Hagger, R, Zadi, Az, Maslekar, Su, Kinross, J, Irukulla, S, Hawkins, W, Wheatstone, S, Magro, T, Bailey, S, Marshall, G, Mccullough, J, Marangoni, G, Leung, El, Borg, Cm, Gopinath, S, Kirkby-Bott, J, Yalamarthi, S, Mirza, S, Brett, M, Ramcharan, S, Pandey, V, Thava, B, Andreani, Sm, Sahay, Sj, Aravind, B, Downey, M, Nicol, D, Whitehouse, P, Sharma, A, Francis, N, Chitsabesan, P, Stewart, Dj, Norcia, Gg, Cucinotta, E, Cianchi, F, Romario, Uf, Taglietti, L, Capelli, P, Garulli, G, Parisi, A, Nitti, D, Guglielmi, A, Alonzo, A, Scandroglio, Is, Moretto, G, Ansaloni, L, Pietrabissa, A, Foschi, D, Vettoretto, N, Ercolani, G, Coppola, M, Colangelo, E, Morandi, E, Niolu, P, Pala, M, Coletti, M, Pisanu, A, Nicolosi, A, Sammarco, G, Berti, S, Soliani, P, Tonini, V, Stella, M, Ceccarelli, G, De Nisco, C, Castagnoli, G, De Nardi, P, Borghi, F, Agresta, F, Benevento, A, Cantafio, S, Cesari, Mc, Rubbini, M, Chetta, G, De Marchi, F, Nora, Mf, Sousa, Hs, Nascimento, Ca, Casimiro, C, Costa, Sd, Rosa, Mj, Carvalho, N, Correia, J, Gomes, Ap, Hill, Ad, Walsh, Tn, Aremu, Ma, Mulsow, J, El-Masry, S, Gillick, J, Garvin, J, Caldwell, M, Mehigan, B, Peirce, Cb, Cooke, F, Mealy, K, Ruano, A, Ais, G, Fueyo, J, Parajó, Ae, Bernal-Sprekelsen, Jc, Monzón-Abad, Ja, Blanco, F, Arroyo, A, Bazán-Hinojo, Mc, Ramos-Bernado, Mi, Lopez-Ruiz, Ja, Golda, T, Julià, D, Cuadrado, Mm, Gómez-Abril, Sa, Martinez, J, Aguayo, Jl, Millan, M, Alvarez-Gallego, M, Muinelo-Lorenzo, M, Parra, Jm, Muñoz-Muñoz, E, De Chaves-Rodríguez PG, Cánovas-Moreno, G, Rodriguez-Lopez, M, Segura-Sampedro, Jj, García-Granero, A, Redondo-Calvo, Fj, Dyson, S, Thakur, D, Swords, C, Siaw, O, Zelazek, M, Woo, R, Badran, A, Aruparayil, N, Christopoulos, P, Chambers, B, O'Neill, N, Long, Rh, Mccaughey, P, Wong, Ml, Mccain, Rs, Lennox-Warburton, Hc, Moore, C, Manektella, Km, Mcilwaine, S, Rupani, S, Simpson, Dj, Wauchope, J, Ng, M, Christian, L, Crone, A, Sacks, R, Symons, N, Lazzaro, A, Patil, Sd, Roomi, S, Silva, I, Hodgson, Jm, Ly, C, Froud, H, Patel, H, Cay, P, Karwal, Rs, Danquah-Boateng, D, Berry, B, Esmail, Hd, Maripi, H, Bilku, D, Mckelvie, Ma, Miller, K, Maina, A, Velho, R, Hasan, R, Clingan, R, Jah, S, Waite, K, Jones, A, Buckley-Jones, S, Lecky-Thompson, L, Saghir, N, Mansoor, S, Mistry, D, Brown, R, Wong, A, Gurung, S, Wensley, F, Fleming, Ta, Griggs, R, Haines, S, Bedoya, S, Beverstock, A, Johnson, J, Govind, G, Niaz, O, Dyal, A, Tokidis, E, Punj, S, Leusink, A, Rudland, I, Kelly, M, Morgan, R, Al-Musawi, S, Lek, C, Gilbert, A, Gosal, A, Mahoney, R, Parwaiz, I, Mitchard, Mj, Ribeiro, B, Merai, H, Dean, Ea, Khan, S, Baginski, A, Mann, C, Foers, W, Jones, L, Woodward, B, Mcwhirter, Dm, Thomas, At, Gilbert, Tg, Weatherburn, Lw, Pilkington, Jp, Cameron, Fc, Clements, Jd, Mccann, C, Davidson, S, Hackney, L, Clements, Js, Martin, A, Du, Dt, Shakoor, Z, Yen, Sk, Adnan, M, Ranathunga, S, Sana, S, Tay, Yh, Chin, My, Gillespie, M, Brown, Ag, Campbell, U, Chatzikonstantinou, M, Mahendran, B, Flack, T, Chowdhary, M, Lim, Jm, Whiteman, E, Shepherd, Ja, Pedder, A, Siggens, Kl, Lai, Cw, Morrison-Jones, V, Hayat, Z, Nehikhare, I, Macleod, C, Quinn, Hc, Brown, A, Neagle, G, Chok, Sm, Carrano, Fm, Abbassi, Oa, Divekar, Ga, Halmer, S, Adams, Re, Davies, Pl, Wong, Sy, Amarasinghe, R, Tague, Le, Jones, E, Singh, J, Boza, K, Kelly, Sd, Morrison, F, Chan, Wh, Wilson, Ej, Awokoya, Oo, Griffiths, Sn, Kirkham, En, Cotton, Ae, Adimonye, A, Leighton, Pa, Abdelrahman, A, Cartwright, H, Gates, Z, Miguras, M, Khan, K, Louw, C, Grove, T, Badenoch, T, Mckeon, J, Wood, Cs, Leitch, Rp, Sgardelis, P, Perera, Mi, Nagarajan, D, Malam, Y, Theodoropoulou, K, Rajagopal, S, Kaptanis, S, Popova, D, Olagbaiye, O, Tayeh, S, Rigby, S, Harris, Mp, Ren, Kz, Liaw, G, Zhou, S, White, F, Marshall, Cm, Mitchell, Jh, Anderson, Dj, Kanakala, V, Hollingsworth, A, Paramasevon, Kr, Milward, J, Ahmed, S, Fanibi, Bf, Ferguson, N, Dickson, Ea, Shaw, Av, Dixon, F, Morrish, S, Dandy, R, Fooks, P, Sharma, P, Islam, N, Tabain, V, Keegan, R, Ahel, J, Alhammali, T, Graveston, J, Balai, Ej, Rothnie, K, Pankin, Gp, Eiben, Ie, Jackson, Nj, Dhar, M, Nash, D, Dharamavaram, S, Seth, M, Chowdhury, F, Rezacova, M, Seneviratne, N, Turner, Ej, Currow, C, Isherwood, Jd, Hobson, Bm, Lui, Dh, Rodger, V, Ting, N, Photiou, D, Taze, D, Lodhia, S, Earnshaw, L, Kumar, K, Neale, A, Bastianpillai, J, Cipparrone, M, Barrie, A, Nash, Z, Anandan, L, Tailor, K, Vinnicombe, Z, Krivan, S, Kuo, R, Giorga, A, Habib, H, Malik, K, Bogdan, M, Mahon-Daly, Fp, Athersmith, Mj, Strange, Ja, Wheeler, C, Summerfield, L, Khaw, Ra, Ashour, O, Iosif, E, Fadel, M, Gopalakrishnan, K, Orme, N, Williams, S, Rashid, M, Sultana, A, Patel, N, Pearson, R, Yasin, T, Bevan, V, Al-Sarireh, B, Brown, M, Mohd, N, Howie, Ee, Poudevigne, M, Paget, C, Rallage, H, Chui, K, Fawzi, F, Layman, S, Okorocha, E, Jama, Gm, Orawiec, P, Kouli, O, Hassane, A, Kilkenny, J, Devine, Aa, Laurenson, M, Slezak, I, Barker, T, Lau, E, Limbada, M, O'Brien, J, Weaver, J, Hajibandeh, S, Shah, J, Mansour, Mm, Malik, Sn, Davis, S, Trew, F, Bandyopadhyay, Sk, Dart, K, Guru-Naidu, S, Callan, R, Nair, Mk, Alani, M, Sezen, E, Salim, S, Shurlock, J, Siddique, K, Forouzanfar, A, Brews, R, Acharya, A, Jain, A, Tozer, Pj, Warusavitarne, J, Emslie, Km, Collier-Wakefield, O, Sivaloganathan, P, Dobson, C, Elseedawy, M, Mcnally, L, Williams, M, Motiwala, Fh, Choi, S, Asmadi, Aa, Burnside, D, Everden, A, Suriyakumar, S, Sandu, L, Kent, Da, Bowen, J, Long, P, Khair, A, Shah, K, Phelan, L, Pierre, R, Dhari, Aa, Hoff, M, Nickson, S, Setshwaelo, T, Chalk, A, Parkola, Mj, Harlinska, A, Chan, T, Dudek, Jg, Rolph, R, Allen, M, Pollard, H, Gormely, R, Finlayson, H, Ljungqvist, G, Peponis, C, Rahman, M, Dhesi, S, Arshad, F, Faris, Ar, Sooriyamoorthy, T, Springate, El, Barnieh, W, Patel, As, Siddiqui, Za, Chishti, Ia, Ayube-Brown, J, Rabie, Mr, Blake, L, Yardimci, E, Nagendram, S, Neophytou, Gi, Henderson, L, Farhan-Alanie, M, Kong, Cy, Ghazala, R, Evans, J, Hussain, N, Kabir, M, Hraishawi, I, Cox, M, Bailey, Ja, Muhibullah, N, Yanni, F, Stevenson, R, Nair, A, Murphy, C, Mcgucken, O, Pandya, R, Bowerman, H, Lafaurie, G, Van Boxel GI, Shanmugarajah, K, Maragouthakis, D, Hanif, Z, Evans, Jd, Yoganathan, S, Richardson, Td, Cook, V, Clark, Gl, Rigney, B, O'Neill, E, Guliani, J, Chan, D, Harper, F, Sian, T, Boereboom, C, Blackwell, J, Hardy, E, Boyd-Carson, H, Couch, Dg, Barter, Ca, Thoukididou, Sn, Hatt, Jr, Jones, Cs, Dean, S, Rajaretnam, N, Masood, M, Thakral, N, Griffith, D, Doherty, C, Longshaw, A, Peprah, D, Mathew, G, Hook, A, Vance-Daniel, J, Ibrahim, Y, Walters, Kj, Whewell, He, Sherif, Ma, Mckenna, M, O'Sullivan, D, Woodrow, C, Gill, S, Johnstone, A, Gentry, R, Irwin, R, Forgie, A, Welsh, S, Ivey, P, Bullivant, Jk, English, Wj, Osterberg, A, Morowala, A, Al-Faham, Z, Islam, S, Tan, E, Sadek, S, Sihra, N, Shrestha, D, Chong, B, Nadeem, A, Fasuyi, Ja, Patel, Mm, Daureeawoo, R, Okekunle, B, Cheruvu, M, Mazumdar, E, Hussain, A, Patel, C, Mcquaid, M, Banks, A, Robinson, A, Khan, Ms, Riaz, W, Verroiotou, M, Cohen, Ja, Kouroumpas, E, Ghaffari, I, Moradzadeh, J, Kamal, M, Gulamhussein, M, Gaines, E, Ghatorae, S, Clark, S, Savill, A, Hutchinson, B, Chapman, J, Wu, F, Creasy, W, Raymond, M, Grosvenor, S, Odeh, A, Malik, Y, Bansal, H, Grant, C, Raofi, A, Ahmed, B, Mai, D, Souter, J, Hamelmann, Rn, Ikram, S, Durbacz, M, Gilliland, N, Salem, A, Chudek, D, Ladwa, N, Storey, R, Fontaine, C, Toomey, D, Miller, B, Oakey, M, Smoker, H, Chapman, Sj, O'Hagan, Sc, Tahir, W, Wilcox, G, Ahmad, A, Akram, F, Baddams, Ts, Boshier, Pr, Fehervari, M, Easdon, S, Ilozue, T, Adam, Me, Jokhan, S, Foster, A, Nambiar, K, Bohra, P, Janardanan, S, Shanmuganathan, V, Maqboul, F, Ettles, C, Wardle, Sd, Martinou, E, Khasria, A, Bagga, R, Motter, D, Mundkur, N, Pan, Y, Akbari, K, Farrell, Sm, Rahim, A, Gummaraju, A, Mahmoud, A, Akinsola, O, Smallcombe, N, Tarazi, M, Hanley, C, Campbell, Um, Franklin, D, Davidson, Jr, Raza, Ss, Krishnamoorthy, A, Rajjoub, Y, Ali, M, Seddon, Tc, Payne, Re, Das, A, Martin, Lm, Naismith, Kn, Venkata, Up, Manda, Vm, Burns, Km, Huang, J, Samuel, M, Docherty, Ja, Cheah, Wl, Ooi, R, Nyeko-Lacek, M, Marsh, L, Prideaux, A, Li, Ch, Poacher, A, Lee, M, Muzaffar, M, Kara, A, Walsh, E, Sunter, H, Roth, N, Roy, C, Mcmorran, D, Turnbull, A, Layton, Gr, Archer, Je, Yang, P, Douka, E, Amin, V, Borghol, K, Blackford, Od, Bond, S, Baker, B, Mohamed, Wo, Williams, R, Garnham, J, Robb, Hd, Allington, J, Cloney, L, Tamborska, A, Kalia, K, Fung, E, Johnston, Z, Lynch, L, Christides, A, Tan, Hl, Cynthia, G, Tsang, B, Rossi, C, Kaubrys, M, Al-Khafaji, N, Jenkins, M, Peiris, Gb, Gunning, S, Nimako, E, Pandya, D, Hever, P, Amayo, A, Bull, C, Clements, C, Al-Sheikh, M, Savioli, F, Long, M, Horsfield, E, Robertson, C, Ogboru, S, Mcilwrath, Ac, Bell, J, Limb, C, Obeid, N, Rich, Je, Balasubramaniam, A, Mashar, R, Taylor, M, Bruce, Js, Dennison, G, Curtis, Nj, Ezerska, E, Ellis, B, Wiggill, S, Tee, A, Ng, S, Carder, C, Abdelwahed, A, Chandler, Sb, Tinsley, Bj, Finotti, E, Occhioni, G, Cossu, F, Vulcano, I, Viscosi, F, Michelini, M, Compagnoni, B, Sepe, C, Isolani, Sm, Regina, G, Alagna, V, Martorelli, G, Gabbianelli, C, Moroni, P, Zuin, M, Conci, S, Lazzari, G, Costamagna, D, Zurleni, Tz, Altomare, Ma, Desiderio, J, Di Cintio, A, Gemini, A, Trastulli, S, Viviani, E, Tomasoni, M, Montori, G, Harder, G, Argenti, F, Malabarba, S, Checcacci, P, Montanelli, P, Guerra, F, Skalamera, I, Staderini, F, Grandi, S, Nelli, T, Coratti, F, Sorrentino, L, Maffioli, A, Cavallo, D, Bondurri, A, Groppo, G, Curti, R, Solaini, L, Xidas, A, Manias, T, Delogu, D, Vacca, A, Solinas, L, Corbellini, C, Fiore, L, Nigro, A, Santurro, L, Angrisani, M, Sparta, C, Lorettu, A, Mura, Fa, Ruggiu, Gv, Pirari, Pf, Pau, R, Melis, M, Piu, F, Patti, S, Deserra, A, Angelieri, D, Del Basso, C, Rossi, D, Iannone, I, De Padua, C, Giubilo, C, Falaschi, F, Cirillo, B, Gordini, L, Podda, F, Sanna, S, Saba, A, Poillucci, G, Pinna, E, Messina, A, Sena, G, Cardona, R, De Luca, E, Sacco, R, Vescio, G, Ammendola, M, Romano, R, Bianco, A, Bonfante, P, D'Ambra, L, Feleppa, C, Gennai, A, Lizzi, V, Moggia, E, Imperatore, M, Bolzon, S, Belvedere, A, Amaducci, E, Ripoli, Mc, Segalini, E, Cervellera, M, Vaccari, S, Eretta, Co, O'Neill, R, Llewelyn, O, Jones, N, Clerici, F, Ballabio, M, Andolfi, E, Angelini, M, Fontani, A, Miranda, E, Scricciolo, M, Provenza, G, Pellicanò, Ga, Pulighe, F, Argenio, G, Melis, A, Balestra, F, Anania, M, Cruccu, A, Massaiu, C, Murru, Ml, Martino, A, Luzzi, Ap, La Valle, G, Chillitupa, Cz, Bartoli, A, Conti, D, Spaziani, A, Bellochi, R, Listorti, C, Salandini, Mc, Carlucci, M, Tenconi, Sm, Cannavò, M, Marano, A, Giuffrida, Mc, Cannata, G, Pellegrino, L, Giraudo, G, Baraghini, M, Garzi, A, Giudicissi, R, Zalla, T, Romoli, L, Vannucchi, A, Giani, I, Feroci, F, Calussi, M, Ribaudo, M, Fiorot, A, Stecca, T, Nistri, C, Fornasier, C, Valiani, Sv, Brunelli, Db, Evoli, Le, Giuliani, Ng, Contine, Ac, Renzi, Cr, Feo, Cv, Anania, G, Carcoforo, P, Aisoni, F, Licari, L, Tutino, R, Cocorullo, G, Silvestri, V, De Marco, P, Fontana, T, Orlando, G, Falco, N, Baseggio, M, Napetti, S, Mella, A, Rossi, Gm, Chimetto, A, Cosci, M, Bonomo, M, Scialandrone, G, Chetta, N, Carvalho, Lc, Magalhães, Js, Pereira, Am, Fernandes, C, Fareleira, A, Gonçalves, D, Pais, M, Pereira, A, Resende, Fm, Correia, D, Cardoso, D, Tojal, A, Santos, Sc, Barbosa, L, Louro, Hc, Bairos, F, Martins, Fm, Messias, Fm, Ferreira, Ms, Borges, Fc, Botelho, P, Lima, M, Valente, Pm, João, Aa, Guimarães, Jm, Rocha, R, Nogueira, St, Kabir, U, Wong, C, Rahmani, Ls, Tan, S, Chng, S, Jasinski, B, Cheng, Sa, Mardhiah, S, Mcglynn, K, Hannan, E, Burke, J, Haveliwala, Z, O'Neill, M, Boland, M, Hayes, C, Fox, A, Zaborowski, A, Mitru, Rm, Mc-Dermott, A, Coyle, D, Stoica, I, Mcmahon, Sv, Laughlin, Dm, Kannegieser-Bailey, M, Murphy, R, Muntean, A, Shet, S, Thomas, L, De Freitas, S, Quill, S, Aljorfi, A, Soh, B, Law, Jj, Hartnett, J, Jansen, T, Gilgan, J, Jung, J, Scanlon, K, Szucs, A, Ahern, Dp, Redmond, Ae, Edwards, Se, Manoharan, P, Brennan, S, Abdelgadir, Am, Mckevitt, Kl, Zarog, Ma, Ahmed, G, Bukhari, W, Ahad, A, Paniagua, M, Samartin, C, Primo, Jc, Garrido, L, Lopez, M, Rufo, E, Trostchansky, I, Rodriguez, L, Infante, H, Acosta, A, Cremades, P, Cidoncha, A, Olmos, V, Oliva, I, Santamaria, C, Cavero, A, Calvo, H, Suero, Ca, Maderuelo, Vm, Galvez, P, Hernando, A, Eguaras, I, Recreo, Ac, García-Carrero, M, Moreda, R, De Andres, U, Del Pozo, E, Calvo, M, Moratalla, Cn, Ronda, Rn, Contreras, Rg, De Burgos CB, Cortés, Gv, Martínez, Cc, Agudo, Ar, Soriano, Jt, Ramos, Xh, Echazarreta, E, Elia, M, Hernaez, A, Sanchez, L, Vallejo-Bernad, C, Oliver, Jr, Sánchez-Rubio, M, Kälviäinen, Hk, Genzor, S, González-Nicolás, T, Puerta, E, Laviano, E, Gimenez, T, Fermiñán, A, Muriel-Álvarez, P, Sierra-Grañón, Je, Escoll-Rufino, J, Cuello-Guzmán, E, Mestres-Petit, N, Merichal-Resina, M, Pinillos-Somalo, A, Gomez-Carmona, Z, Vazquez-Fernandez, Ap, Trujillo-Diaz, Jj, Couso, Jr, Fernández, Md, Riera, E, Espinosa, J, Carral-Freire, M, Martínez-Almeida, R, Santarrufina-Martínez, S, Sebastián-Tomás, Jc, Gonzálvez-Guardiola, P, Fernández, Ec, Mozo, As, Stoyanov, Ti, Santamaría, Pc, Grimaldo, Eg, Fernández-Candela, A, Curtis-Martínez, C, Del-Valle-Ruiz, Sr, Sánchez-Cifuentes, A, Ramírez-Faraco, M, López, Af, Leon, C, Kumar, S, Fornell-Ariza, M, Ayllón-Gámez, S, Peña-Barturen, C, Ojea-Ruiz-Yherla, L, Saavedra-Chacón, M, Perez-Calvo, J, Gomez-Facundo, H, Riba-Combatti, L, Manas, Oc, De-Soto-Cardenal, B, De-La-Herranz-Guerrero, P, Dominguez-Sanchez, C, Gamero-Huaman, Jc, Suarez-Cabrera, A, Ramirez-Redondo, Aa, Lara-Fernandez, Y, Bascuas-Rodrigo, B, Lopez-Duran, Bl, Pigem, A, Gil, J, Salvador, H, Planellas, P, Farrés, R, Caballero, A, Arnau, M, Tapiolas, I, Ridaura, N, Roncero, Ls, Collado-Roura, F, Fijo, Lm, Cormenzana, Ob, Viñas, Nl, Grifell, Ms, Prats, Ma, Torrado, Aa, Sanz-Navarro, S, Contreras-Saiz, E, Solar-García, L, Moreno-Gijón, M, Suárez-Sánchez, A, Díaz-Vico, T, Rodicio-Miravalles, Jl, García-Gutierrez, C, Pila, U, Melone, S, Martin-Prieto, L, Rojo, Ja, Gonzalez, M, Zorrilla, L, Garcia-Marin, Ja, Baeza-Murcia, M, Pellicer-Franco, E, Jimenez-Ballester, Ma, Asensio-Gomez, L, Gortazar-De-Las-Casas, S, Guevara-Martinez, J, Ramirez, L, Verea, S, Anguita, F, Navarro, G, Criado, Adc, Lara, Mc, Martinez, Et, Sanchez-Martinez, A, Hernandez-Gimenez, L, Galofre-Recasens, M, Ferrer-Vilela, I, Pérez-Sanchez, Le, Esteves, Mb, Menéndez-Moreno, A, Baz-Figueroa, C, Rosat, A, Hontoria, Ms, García, Na, Gracia-Roman, R, Pascua-Sole, M, Pino-Perez, O, García-Pérez, Jm, Pineño-Flores, C, Ambrona-Zafra, D, Sancho-Muriel, J, Alvarez, E, Jiménez-Rosellón, R, Daga, O, Alberca-Paramo, A, Sanchez-Garcia, S, García-Santos, E, Pareja-Ciuró, F, Olivares-Oliver, C, Navarro-Morales, L, Tamayo-López, Mj, Tinoco-González, J, García-Rivera, Co, Agua, Ia, Moreno-Suero, F, Pereira-Mosquera, E, Zerpa, C, Llacer, E, Diaz, A, Caro, A, Feliu, F, Franco, M, Escuder, J, Abellan, M, Padilla, E, Mambrilla-Herrero, S, Plua-Muniz, Kt, Bailon-Cuadrado, M, Tejero-Pintor, Fj, Choolani-Bhojwani, E, Vila-Zarate, C, Delgado-Plasencia, Lj, Ponchietti, L, Cousins, L, Busuttil, A, Baird, C, Drye, N, Brown, Od, Mansour, S, Anderson, O, Mahapatra, R, Clements, Ja, D'Souza, N, Littlehales, Dj, Tang, Am, Byrne, Be, Cunha, P, Ogbuokiri, C, Eiben, P, Gravante, G, Kho, H, Dobbs, S, Doulias, T, Ng, J, Wilson, M, Venugopal, R, Wolff, J, Akhtar, K, Walji, Hd, Tognarelli, Jm, Knight, Ka, Ansari, A, Hussaini, Sa, Wright, E, Brewer, H, Rinkoff, S, Harries, Rl, Fairfield, Cj, Abbott, T, Jackson, A, Wright, Hl, Walters, U, Carney, K, Logan, Pc, Mughal, Z, Strachan, E, Chasty, B, Ma, J, Mazzeo, C, Badii, B, Armellini, A, Grassia, M, Perin, A, Ruzzenente, A, Magnoli, M, Depalma, N, Longheu, A, Papandrea, M, Dova, L, De Prizio, M, Gusai, Gp, Di Zitti, L, Geretto, P, Azabdaftari, A, Chianese, G, Elbetti, C, Ruffolo, C, Giaccari, S, Devezas, V, Ferreira, Js, Peixoto, R, Alshafei, A, Simo, V, José, Hs, Ugarte-Sierra, B, Salva, Ab, Gómez, N, Marinello, F, Medina-Arana, V, Vega, L, Ballester, Mm, Espina, B, Prieto-Nieto, Mi, Rodríguez, Ec, Padilla-Valverde, D, Duran-Muñoz-Cruzado, Vm., Nepogodiev, D, Matthews, Jh, Morley, Gl, Naumann, Dn, Ball, A, Chauhan, P, Bhanderi, S, Mohamed, I, Glasbey, Jc, Wilkin, R, Drake, Tm, Clements, J, Blencowe, N, Herrod, P, Pata, F, Frasson, M, Blanco-Colino, R, Soares, A, Bhangu, A, Jain, S, Amuthalingam, T, Tyler, R, Griffiths, Ea, Pinkney, Td, Gee, O, Morton, Dg, Beggs, A, Beral, D, Bowley, D, Cruickshank, N, Daniels, I, Griffiths, E, Hornby, St, Lund, Jn, Marriott, P, Singh, P, Smart, Nj, Speake, D, Thompson, C, Torkington, J, Torrance, A, Vohra, R, Warren, O, Winter, Dc, Pellino, G, Sgrò, A, Simioni, A, Farina, V, Podda, M, Di Saverio, S, Birindelli, A, Pasquali, S, Itsurg, Surg, Pt, Bolton, W, Bradshaw, Cj, Chean, C, Harris, G, Haddow, Jb, Jamieson, Nb, Mccain, S, Mason, J, Milgrom, D, Nana, Gr, Mohamed, Mn, Brien, Jo, Pearce, J, Rabie, M, Sahnan, K, Sarmah, P, Skerritt, C, Ghazanfar, Ma, Sreedharan, L, Kabwama, S, Gray, Rt, Kamande, Iw, Nazarian, S, Dar, Fa, Misky, At, Arunachalam, S, Twum-Barima, C, Mohamed, Im, Connor, Kl, Coe, Po, Kosti, A, Elshaer, M, Colvin, Da, Charalambous, Mp, Yeung, K, Merker, L, Morrison, T, Thaventhiran, Aj, Gilbert, Tm, Clements, Jm, Hicks, G, Afshar, S, Mckinley, Nc, Assaf, N, Hanna, T, Macinnes, E, Thavanesan, N, Dubois, A, Palani-Velu, Lk, Tezas, S, Yow, L, Radwan, Rw, Abdelrahman, M, Lee, Ka, Zarka, Za, Mcdowall, Na, Tan, Cy, Venn, Ml, Ashmore, Dl, Whitehorn, Se, Golder, Am, Reddy, A, Delimpalta, C, Kay, Oh, Shah, Sm, Eiben, I, Doyle, C, Tudyka, V, Issa, E, West, H, Brewer, Hk, Farrow, Ez, Taylor, N, Smart, Cj, Griffiths, Np, Halkias, C, Vitish-Sharma, P, Knight, Sr, Mowbray, Ng, Olivier, Jb, Lee, Kj, Clement, Kd, Chrastek, D, Panda, N, Connor, Mj, Fahmy, Se, Bryan, E, Ngu, W, Adegbola, So, Vaughan, Em, Stupalkowska, W, Simmonds, L, Malik, A, Hussein, A, Karim, Mj, Singhal, T, Ormiston, R, Kung, V, Rabie, Ma, Park, Jh, Lal, N, Worku, D, D'Auria, M, Ang, A, Orizu, M, Gammeri, E, Clough, E, Choy, Ch, Lawday, S, Hann, Aj, Robinson, D, Wardle, Bg, Mcdonnell, D, Rutherford, Dg, Hickey, Lm, Garg, Ag, Rezvani, S, Bell, Cr, Mahmood, F, Rehman, S, Donaldson, G, Peleki, A, Pearce, L, Sharp, Ol, Singh, S, Thompson, Db, El-Tayar, O, Hollyman, M, Rupasinghe, Sn, Toomey, Db, Murray, Mp, Amtul, N, Mersh, Rj, Newton, Rc, Al-Khyatt, W, Stephens, Gf, Abbas, Sh, Iqbal, Mr, Brown, Ce, Renshaw, S, Hureibi, Ka, Pullabatla-Venkata, Up, Donohoe, No, Myatt, A, Egan, Rj, Rangarajan, K, Trail, M, Mckay, Sc, Engall, N, Jerome, E, Townsend, Dc, Patel, By, Pronin, S, Chandratreya, N, Choong, Jh, Mohamed, Tm, Hudson-Peacock, Nj, Manson, R, Hebbar, K, Mothe, B, Weegenaar, Cr, Saad, M, Bowman, Cr, Serventi, F, Fleres, F, Foppa, C, Pata, G, Baronio, G, Pertile, D, Lucchi, A, Sagnotta, A, Maretto, I, Campagnaro, T, Gatti, M, Gjoni, E, Roscio, F, Inama, M, Coccolini, F, Colombo, F, Avanzolini, A, Aresu, S, De-Manzoni-Garberini, A, Merlini, Da, Chessa, A, Tamini, N, Mulas, S, Cillara, N, Coletta, D, Atzeni, J, Erdas, E, Gallo, G, Francone, E, Di Gioia, P, Bianchi, Cl, Ferrara, F, Biancafarina, A, Scabini, S, Marano, L, Miegge, A, Sasia, D, Savino, G, Scatizzi, M, D'Amico, Fe, Arcuri, Ga, Gavagna, L, Salamone, G, Tatulli, F, Goldin, E, Matos, Ml, Caldeira, Ab, Romano, J, Pereira, J, Azevedo, J, Azevedo, Jm, Simoes, J, Silva, A, O'Leary, Dp, Kennedy, Nd, Quinn, Em, Zhang, Ay, Neary, Pm, De-Marchi, Ja, O'Connor, Br, Wijesundera, K, Foley, Nm, Wong, J, Tiedt, La, Bolger, Jc, Connelly, Tm, Ahmed, O, Vigorita, V, García, V, Arredondo, J, Redondo, E, Sainz, B, Aldrey, I, Landaluce-Olavarria, A, Gómez, Aa, Cordoba, E, Sánchez-Fuentes, Mn, Cerdán-Santacruz, C, Beltran-De-Heredia, J, García, M, Veres, T, García-Novoa, A, Abellán, Am, García-Catalá, L, Ruiz-Marín, M, Menendez, P, Roldán-Ortiz, S, Navas-Cuéllar, Ja, Sabia, D, Gomez-Rosado, Jc, Navidad, M, Caula, C, Sanchez, Er, Espin-Basany, E, Fernández-Martínez, D, Bravo-Gutiérrez, Af, Payá-Llorente, C, Dujovne, P, Lima, F, Soria-Aledo, V, Gomez, Cj, Pascual-Miguelañez, I, Muinelo, M, Alvarez, Cm, Vargas-Pierola, Hj, Vallve-Bernal, M, Hidalgo-Rosas, Jm, Arenal-Vera, Jj, Sena-Ruiz, F, Sanchez-Guillen, L, Villarejo-Campos, P, Tallon-Aguilar, L, Garcea, A, Bennett, Jm, Whittaker, L, Gidwani, Al, Byrnes, Ck, Saunders, S, Shiwani, Mh, Ashraf, N, Venkatasubramaniam, Ak, Bevan, Ke, Mcarthur, D, Mustafa, Ak, Griffith, Jp, Blazeby, Jm, Charalabopoulos, A, Campbell, W, Reese, G, Warren, Oj, Peacock, M, Menzies, D, Jenner, D, Eardley, Nj, Yoong, S, Abulafi, M, Avalapati, H, Thompson, R, Nastro, P, Kochupapy, R, Stubbs, Bm, Mcintyre, R, Crozier, J, Patel, Pk, Pento, V, Beasley, Wd, Roxburgh, C, Youssef, H, Alexander, R, Denley, S, Di Franco, F, Quddus, A, Saha, A, Hunter, I, Hannay, J, Velchuru, Vr, Bond-Smith, G, Salama, Y, Bhargava, A, Panagiotopoulos, Sp, Watson, N, Garcea, G, Boddy, Ap, Dunning, Pg, Lloyd, G, Gurjar, Sv, Hill, J, Andrews, B, Singh, A, Ruzvidzo, F, Shingler, G, Mahon, D, Elgaddal, S, Payne, Cj, Shaikh, Ia, Dalmia, S, Nair, M, Finch, Jg, Chapple, K, Bawa, S, Watfah, J, Carden, Ca, Makhija, R, Rao, M, Sarveswaran, J, Vijay, V, Rekhraj, S, Knight, B, Siddiqui, Mn, Sebastian, Jf, Glen, P, Vakis, S, Ebied, H, Rajaram, R, Gray, J, Mcgrath, D, Faulkner, G, Gopalswamy, S, Varcada, M, Woodward, A, Williams, Gl, Szentpali, K, Ravindran, R, Bronder, C, Thaha, Ma, Rate, A, Shetty, Vd, Rao, V, Sajid, M, Clements, B, Patel, Rt, Mason, C, Branagan, G, Maude, K, Kaur, G, Lyons, A, Ainsworth, P, Hagger, R, Zadi, Az, Maslekar, Su, Kinross, J, Irukulla, S, Hawkins, W, Wheatstone, S, Magro, T, Bailey, S, Marshall, G, Mccullough, J, Marangoni, G, Leung, El, Borg, Cm, Gopinath, S, Kirkby-Bott, J, Yalamarthi, S, Mirza, S, Brett, M, Ramcharan, S, Pandey, V, Thava, B, Andreani, Sm, Sahay, Sj, Aravind, B, Downey, M, Nicol, D, Whitehouse, P, Sharma, A, Francis, N, Chitsabesan, P, Stewart, Dj, Norcia, Gg, Cucinotta, E, Cianchi, F, Romario, Uf, Taglietti, L, Capelli, P, Garulli, G, Parisi, A, Nitti, D, Guglielmi, A, Alonzo, A, Scandroglio, I, Moretto, G, Ansaloni, L, Pietrabissa, A, Foschi, D, Vettoretto, N, Ercolani, G, Coppola, M, Colangelo, E, Morandi, E, Niolu, P, Pala, M, Coletti, M, Pisanu, A, Nicolosi, A, Sammarco, G, Berti, S, Soliani, P, Tonini, V, Stella, M, Ceccarelli, G, De Nisco, C, Castagnoli, G, De Nardi, P, Borghi, F, Agresta, F, Benevento, A, Cantafio, S, Cesari, Mc, Rubbini, M, Chetta, G, De Marchi, F, Nora, Mf, Sousa, H, Nascimento, Ca, Casimiro, C, Costa, Sd, Rosa, Mj, Carvalho, N, Correia, J, Gomes, Ap, Hill, Ad, Walsh, Tn, Aremu, Ma, Mulsow, J, El-Masry, S, Gillick, J, Garvin, J, Caldwell, M, Mehigan, B, Peirce, Cb, Cooke, F, Mealy, K, Ruano, A, Ais, G, Fueyo, J, Parajó, Ae, Bernal-Sprekelsen, Jc, Monzón-Abad, Ja, Blanco, F, Arroyo, A, Bazán-Hinojo, Mc, Ramos-Bernado, Mi, Lopez-Ruiz, Ja, Golda, T, Julià, D, Cuadrado, Mm, Gómez-Abril, Sa, Martinez, J, Aguayo, Jl, Millan, M, Alvarez-Gallego, M, Muinelo-Lorenzo, M, Parra, Jm, Muñoz-Muñoz, E, De Chaves-Rodríguez, Pg, Cánovas-Moreno, G, Rodriguez-Lopez, M, Segura-Sampedro, Jj, García-Granero, A, Redondo-Calvo, Fj, Dyson, S, Thakur, D, Swords, C, Siaw, O, Zelazek, M, Woo, R, Badran, A, Aruparayil, N, Christopoulos, P, Chambers, B, O'Neill, N, Long, Rh, Mccaughey, P, Wong, Ml, Mccain, R, Lennox-Warburton, Hc, Moore, C, Manektella, Km, Mcilwaine, S, Rupani, S, Simpson, Dj, Wauchope, J, Ng, M, Christian, L, Crone, A, Sacks, R, Symons, N, Lazzaro, A, Patil, Sd, Roomi, S, Silva, I, Hodgson, Jm, Ly, C, Froud, H, Patel, H, Cay, P, Karwal, R, Danquah-Boateng, D, Berry, B, Esmail, Hd, Maripi, H, Bilku, D, Mckelvie, Ma, Miller, K, Maina, A, Velho, R, Hasan, R, Clingan, R, Jah, S, Waite, K, Jones, A, Buckley-Jones, S, Lecky-Thompson, L, Saghir, N, Mansoor, S, Mistry, D, Brown, R, Wong, A, Gurung, S, Wensley, F, Fleming, Ta, Griggs, R, Haines, S, Bedoya, S, Beverstock, A, Johnson, J, Govind, G, Niaz, O, Dyal, A, Tokidis, E, Punj, S, Leusink, A, Rudland, I, Kelly, M, Morgan, R, Al-Musawi, S, Lek, C, Gilbert, A, Gosal, A, Mahoney, R, Parwaiz, I, Mitchard, Mj, Ribeiro, B, Merai, H, Dean, Ea, Khan, S, Baginski, A, Mann, C, Foers, W, Jones, L, Woodward, B, Mcwhirter, Dm, Thomas, At, Gilbert, Tg, Weatherburn, Lw, Pilkington, Jp, Cameron, Fc, Clements, Jd, Mccann, C, Davidson, S, Hackney, L, Martin, A, Du, Dt, Shakoor, Z, Yen, Sk, Adnan, M, Ranathunga, S, Sana, S, Tay, Yh, Chin, My, Gillespie, M, Brown, Ag, Campbell, U, Chatzikonstantinou, M, Mahendran, B, Flack, T, Chowdhary, M, Lim, Jm, Whiteman, E, Shepherd, Ja, Pedder, A, Siggens, Kl, Lai, Cw, Morrison-Jones, V, Hayat, Z, Nehikhare, I, Macleod, C, Quinn, Hc, Brown, A, Neagle, G, Chok, Sm, Carrano, Fm, Abbassi, Oa, Divekar, Ga, Halmer, S, Adams, Re, Davies, Pl, Wong, Sy, Amarasinghe, R, Tague, Le, Jones, E, Singh, J, Boza, K, Kelly, Sd, Morrison, F, Chan, Wh, Wilson, Ej, Awokoya, Oo, Griffiths, Sn, Kirkham, En, Cotton, Ae, Adimonye, A, Leighton, Pa, Abdelrahman, A, Cartwright, H, Gates, Z, Miguras, M, Khan, K, Louw, C, Grove, T, Badenoch, T, Mckeon, J, Wood, C, Leitch, Rp, Sgardelis, P, Perera, Mi, Nagarajan, D, Malam, Y, Theodoropoulou, K, Rajagopal, S, Kaptanis, S, Popova, D, Olagbaiye, O, Tayeh, S, Rigby, S, Harris, Mp, Ren, Kz, Liaw, G, Zhou, S, White, F, Marshall, Cm, Mitchell, Jh, Anderson, Dj, Kanakala, V, Hollingsworth, A, Paramasevon, Kr, Milward, J, Ahmed, S, Fanibi, Bf, Ferguson, N, Dickson, Ea, Shaw, Av, Dixon, F, Morrish, S, Dandy, R, Fooks, P, Sharma, P, Islam, N, Tabain, V, Keegan, R, Ahel, J, Alhammali, T, Graveston, J, Balai, Ej, Rothnie, K, Pankin, Gp, Eiben, Ie, Jackson, Nj, Dhar, M, Nash, D, Dharamavaram, S, Seth, M, Chowdhury, F, Rezacova, M, Seneviratne, N, Turner, Ej, Currow, C, Isherwood, Jd, Hobson, Bm, Lui, Dh, Rodger, V, Ting, N, Photiou, D, Taze, D, Lodhia, S, Earnshaw, L, Kumar, K, Neale, A, Bastianpillai, J, Cipparrone, M, Barrie, A, Nash, Z, Anandan, L, Tailor, K, Vinnicombe, Z, Krivan, S, Kuo, R, Giorga, A, Habib, H, Malik, K, Bogdan, M, Mahon-Daly, Fp, Athersmith, Mj, Strange, Ja, Wheeler, C, Summerfield, L, Khaw, Ra, Ashour, O, Iosif, E, Fadel, M, Gopalakrishnan, K, Orme, N, Williams, S, Rashid, M, Sultana, A, Patel, N, Pearson, R, Yasin, T, Bevan, V, Al-Sarireh, B, Brown, M, Mohd, N, Howie, Ee, Poudevigne, M, Paget, C, Rallage, H, Chui, K, Fawzi, F, Layman, S, Okorocha, E, Jama, Gm, Orawiec, P, Kouli, O, Hassane, A, Kilkenny, J, Devine, Aa, Laurenson, M, Slezak, I, Barker, T, Lau, E, Limbada, M, O'Brien, J, Weaver, J, Hajibandeh, S, Shah, J, Mansour, Mm, Malik, Sn, Davis, S, Trew, F, Bandyopadhyay, Sk, Dart, K, Guru-Naidu, S, Callan, R, Nair, Mk, Alani, M, Sezen, E, Salim, S, Shurlock, J, Siddique, K, Forouzanfar, A, Brews, R, Acharya, A, Jain, A, Tozer, Pj, Warusavitarne, J, Emslie, Km, Collier-Wakefield, O, Sivaloganathan, P, Dobson, C, Elseedawy, M, Mcnally, L, Williams, M, Motiwala, Fh, Choi, S, Asmadi, Aa, Burnside, D, Everden, A, Suriyakumar, S, Sandu, L, Kent, Da, Bowen, J, Long, P, Khair, A, Shah, K, Phelan, L, Pierre, R, Dhari, Aa, Hoff, M, Nickson, S, Setshwaelo, T, Chalk, A, Parkola, Mj, Harlinska, A, Chan, T, Dudek, Jg, Rolph, R, Allen, M, Pollard, H, Gormely, R, Finlayson, H, Ljungqvist, G, Peponis, C, Rahman, M, Dhesi, S, Arshad, F, Faris, Ar, Sooriyamoorthy, T, Springate, El, Barnieh, W, Patel, A, Siddiqui, Za, Chishti, Ia, Ayube-Brown, J, Rabie, Mr, Blake, L, Yardimci, E, Nagendram, S, Neophytou, Gi, Henderson, L, Farhan-Alanie, M, Kong, Cy, Ghazala, R, Evans, J, Hussain, N, Kabir, M, Hraishawi, I, Cox, M, Bailey, Ja, Muhibullah, N, Yanni, F, Stevenson, R, Nair, A, Murphy, C, Mcgucken, O, Pandya, R, Bowerman, H, Lafaurie, G, Van Boxel, Gi, Shanmugarajah, K, Maragouthakis, D, Hanif, Z, Evans, Jd, Yoganathan, S, Richardson, Td, Cook, V, Clark, Gl, Rigney, B, O'Neill, E, Guliani, J, Chan, D, Harper, F, Sian, T, Boereboom, C, Blackwell, J, Hardy, E, Boyd-Carson, H, Couch, Dg, Barter, Ca, Thoukididou, Sn, Hatt, Jr, Jones, C, Dean, S, Rajaretnam, N, Masood, M, Thakral, N, Griffith, D, Doherty, C, Longshaw, A, Peprah, D, Mathew, G, Hook, A, Vance-Daniel, J, Ibrahim, Y, Walters, Kj, Whewell, He, Sherif, Ma, Mckenna, M, O'Sullivan, D, Woodrow, C, Gill, S, Johnstone, A, Gentry, R, Irwin, R, Forgie, A, Welsh, S, Ivey, P, Bullivant, Jk, English, Wj, Osterberg, A, Morowala, A, Al-Faham, Z, Islam, S, Tan, E, Sadek, S, Sihra, N, Shrestha, D, Chong, B, Nadeem, A, Fasuyi, Ja, Patel, Mm, Daureeawoo, R, Okekunle, B, Cheruvu, M, Mazumdar, E, Hussain, A, Patel, C, Mcquaid, M, Banks, A, Robinson, A, Khan, M, Riaz, W, Verroiotou, M, Cohen, Ja, Kouroumpas, E, Ghaffari, I, Moradzadeh, J, Kamal, M, Gulamhussein, M, Gaines, E, Ghatorae, S, Clark, S, Savill, A, Hutchinson, B, Chapman, J, Wu, F, Creasy, W, Raymond, M, Grosvenor, S, Odeh, A, Malik, Y, Bansal, H, Grant, C, Raofi, A, Ahmed, B, Mai, D, Souter, J, Hamelmann, Rn, Ikram, S, Durbacz, M, Gilliland, N, Salem, A, Chudek, D, Ladwa, N, Storey, R, Fontaine, C, Toomey, D, Miller, B, Oakey, M, Smoker, H, Chapman, Sj, O'Hagan, Sc, Tahir, W, Wilcox, G, Ahmad, A, Akram, F, Baddams, T, Boshier, Pr, Fehervari, M, Easdon, S, Ilozue, T, Adam, Me, Jokhan, S, Foster, A, Nambiar, K, Bohra, P, Janardanan, S, Shanmuganathan, V, Maqboul, F, Ettles, C, Wardle, Sd, Martinou, E, Khasria, A, Bagga, R, Motter, D, Mundkur, N, Pan, Y, Akbari, K, Farrell, Sm, Rahim, A, Gummaraju, A, Mahmoud, A, Akinsola, O, Smallcombe, N, Tarazi, M, Hanley, C, Campbell, Um, Franklin, D, Davidson, Jr, Raza, S, Krishnamoorthy, A, Rajjoub, Y, Ali, M, Seddon, Tc, Payne, Re, Das, A, Martin, Lm, Naismith, Kn, Venkata, Up, Manda, Vm, Burns, Km, Huang, J, Samuel, M, Docherty, Ja, Cheah, Wl, Ooi, R, Nyeko-Lacek, M, Marsh, L, Prideaux, A, Li, Ch, Poacher, A, Lee, M, Muzaffar, M, Kara, A, Walsh, E, Sunter, H, Roth, N, Roy, C, Mcmorran, D, Turnbull, A, Layton, Gr, Archer, Je, Yang, P, Douka, E, Amin, V, Borghol, K, Blackford, Od, Bond, S, Baker, B, Mohamed, Wo, Williams, R, Garnham, J, Robb, Hd, Allington, J, Cloney, L, Tamborska, A, Kalia, K, Fung, E, Johnston, Z, Lynch, L, Christides, A, Tan, Hl, Cynthia, G, Tsang, B, Rossi, C, Kaubrys, M, Al-Khafaji, N, Jenkins, M, Peiris, Gb, Gunning, S, Nimako, E, Pandya, D, Hever, P, Amayo, A, Bull, C, Clements, C, Al-Sheikh, M, Savioli, F, Long, M, Horsfield, E, Robertson, C, Ogboru, S, Mcilwrath, Ac, Bell, J, Limb, C, Obeid, N, Rich, Je, Balasubramaniam, A, Mashar, R, Taylor, M, Bruce, J, Dennison, G, Curtis, Nj, Ezerska, E, Ellis, B, Wiggill, S, Tee, A, Ng, S, Carder, C, Abdelwahed, A, Chandler, Sb, Tinsley, Bj, Finotti, E, Occhioni, G, Cossu, F, Vulcano, I, Viscosi, F, Michelini, M, Compagnoni, B, Sepe, C, Isolani, Sm, Regina, G, Alagna, V, Martorelli, G, Gabbianelli, C, Moroni, P, Zuin, M, Conci, S, Lazzari, G, Costamagna, D, Zurleni, Tz, Altomare, Ma, Desiderio, J, Di Cintio, A, Gemini, A, Trastulli, S, Viviani, E, Tomasoni, M, Montori, G, Harder, G, Argenti, F, Malabarba, S, Checcacci, P, Montanelli, P, Guerra, F, Skalamera, I, Staderini, F, Grandi, S, Nelli, T, Coratti, F, Sorrentino, L, Maffioli, A, Cavallo, D, Bondurri, A, Groppo, G, Curti, R, Solaini, L, Xidas, A, Manias, T, Delogu, D, Vacca, A, Solinas, L, Corbellini, C, Fiore, L, Nigro, A, Santurro, L, Angrisani, M, Sparta, C, Lorettu, A, Mura, Fa, Ruggiu, Gv, Pirari, Pf, Pau, R, Melis, M, Piu, F, Patti, S, Deserra, A, Angelieri, D, Del Basso, C, Rossi, D, Iannone, I, De Padua, C, Giubilo, C, Falaschi, F, Cirillo, B, Gordini, L, Podda, F, Sanna, S, Saba, A, Poillucci, G, Pinna, E, Messina, A, Sena, G, Cardona, R, De Luca, E, Sacco, R, Vescio, G, Ammendola, M, Romano, R, Bianco, A, Bonfante, P, D'Ambra, L, Feleppa, C, Gennai, A, Lizzi, V, Moggia, E, Imperatore, M, Bolzon, S, Belvedere, A, Amaducci, E, Ripoli, Mc, Segalini, E, Cervellera, M, Vaccari, S, Eretta, Co, O'Neill, R, Llewelyn, O, Jones, N, Clerici, F, Ballabio, M, Andolfi, E, Angelini, M, Fontani, A, Miranda, E, Scricciolo, M, Provenza, G, Pellicanò, Ga, Pulighe, F, Argenio, G, Melis, A, Balestra, F, Anania, M, Cruccu, A, Massaiu, C, Murru, Ml, Martino, A, Luzzi, Ap, La Valle, G, Chillitupa, Cz, Bartoli, A, Conti, D, Spaziani, A, Bellochi, R, Listorti, C, Salandini, Mc, Carlucci, M, Tenconi, Sm, Cannavò, M, Marano, A, Giuffrida, Mc, Cannata, G, Pellegrino, L, Giraudo, G, Baraghini, M, Garzi, A, Giudicissi, R, Zalla, T, Romoli, L, Vannucchi, A, Giani, I, Feroci, F, Calussi, M, Ribaudo, M, Fiorot, A, Stecca, T, Nistri, C, Fornasier, C, Valiani, Sv, Brunelli, Db, Evoli, Le, Giuliani, Ng, Contine, Ac, Renzi, Cr, Feo, Cv, Anania, G, Carcoforo, P, Aisoni, F, Licari, L, Tutino, R, Cocorullo, G, Silvestri, V, De Marco, P, Fontana, T, Orlando, G, Falco, N, Baseggio, M, Napetti, S, Mella, A, Rossi, Gm, Chimetto, A, Cosci, M, Bonomo, M, Scialandrone, G, Chetta, N, Carvalho, Lc, Magalhães, J, Pereira, Am, Fernandes, C, Fareleira, A, Gonçalves, D, Pais, M, Pereira, A, Resende, Fm, Correia, D, Cardoso, D, Tojal, A, Santos, Sc, Barbosa, L, Louro, Hc, Bairos, F, Martins, Fm, Messias, Fm, Ferreira, M, Borges, Fc, Botelho, P, Lima, M, Valente, Pm, João, Aa, Guimarães, Jm, Rocha, R, Nogueira, St, Kabir, U, Wong, C, Rahmani, L, Tan, S, Chng, S, Jasinski, B, Cheng, Sa, Mardhiah, S, Mcglynn, K, Hannan, E, Burke, J, Haveliwala, Z, O'Neill, M, Boland, M, Hayes, C, Fox, A, Zaborowski, A, Mitru, Rm, Mc-Dermott, A, Coyle, D, Stoica, I, Mcmahon, Sv, Laughlin, Dm, Kannegieser-Bailey, M, Murphy, R, Muntean, A, Shet, S, Thomas, L, De Freitas, S, Quill, S, Aljorfi, A, Soh, B, Law, Jj, Hartnett, J, Jansen, T, Gilgan, J, Jung, J, Scanlon, K, Szucs, A, Ahern, Dp, Redmond, Ae, Edwards, Se, Manoharan, P, Brennan, S, Abdelgadir, Am, Mckevitt, Kl, Zarog, Ma, Ahmed, G, Bukhari, W, Ahad, A, Paniagua, M, Samartin, C, Primo, Jc, Garrido, L, Lopez, M, Rufo, E, Trostchansky, I, Rodriguez, L, Infante, H, Acosta, A, Cremades, P, Cidoncha, A, Olmos, V, Oliva, I, Santamaria, C, Cavero, A, Calvo, H, Suero, Ca, Maderuelo, Vm, Galvez, P, Hernando, A, Eguaras, I, Recreo, Ac, García-Carrero, M, Moreda, R, De Andres, U, Del Pozo, E, Calvo, M, Moratalla, Cn, Ronda, Rn, Contreras, Rg, De Burgos, Cb, Cortés, Gv, Martínez, Cc, Agudo, Ar, Soriano, Jt, Ramos, Xh, Echazarreta, E, Elia, M, Hernaez, A, Sanchez, L, Vallejo-Bernad, C, Oliver, Jr, Sánchez-Rubio, M, Kälviäinen, Hk, Genzor, S, González-Nicolás, T, Puerta, E, Laviano, E, Gimenez, T, Fermiñán, A, Muriel-Álvarez, P, Sierra-Grañón, Je, Escoll-Rufino, J, Cuello-Guzmán, E, Mestres-Petit, N, Merichal-Resina, M, Pinillos-Somalo, A, Gomez-Carmona, Z, Vazquez-Fernandez, Ap, Trujillo-Diaz, Jj, Couso, Jr, Fernández, Md, Riera, E, Espinosa, J, Carral-Freire, M, Martínez-Almeida, R, Santarrufina-Martínez, S, Sebastián-Tomás, Jc, Gonzálvez-Guardiola, P, Fernández, Ec, Mozo, A, Stoyanov, Ti, Santamaría, Pc, Grimaldo, Eg, Fernández-Candela, A, Curtis-Martínez, C, Del-Valle-Ruiz, Sr, Sánchez-Cifuentes, A, Ramírez-Faraco, M, López, Af, Leon, C, Kumar, S, Fornell-Ariza, M, Ayllón-Gámez, S, Peña-Barturen, C, Ojea-Ruiz-Yherla, L, Saavedra-Chacón, M, Perez-Calvo, J, Gomez-Facundo, H, Riba-Combatti, L, Manas, Oc, De-Soto-Cardenal, B, De-La-Herranz-Guerrero, P, Dominguez-Sanchez, C, Gamero-Huaman, Jc, Suarez-Cabrera, A, Ramirez-Redondo, Aa, Lara-Fernandez, Y, Bascuas-Rodrigo, B, Lopez-Duran, Bl, Pigem, A, Gil, J, Salvador, H, Planellas, P, Farrés, R, Caballero, A, Arnau, M, Tapiolas, I, Ridaura, N, Roncero, L, Collado-Roura, F, Fijo, Lm, Cormenzana, Ob, Viñas, Nl, Grifell, M, Prats, Ma, Torrado, Aa, Sanz-Navarro, S, Contreras-Saiz, E, Solar-García, L, Moreno-Gijón, M, Suárez-Sánchez, A, Díaz-Vico, T, Rodicio-Miravalles, Jl, García-Gutierrez, C, Pila, U, Melone, S, Martin-Prieto, L, Rojo, Ja, Gonzalez, M, Zorrilla, L, Garcia-Marin, Ja, Baeza-Murcia, M, Pellicer-Franco, E, Jimenez-Ballester, Ma, Asensio-Gomez, L, Gortazar-De-Las-Casas, S, Guevara-Martinez, J, Ramirez, L, Verea, S, Anguita, F, Navarro, G, Criado, Adc, Lara, Mc, Martinez, Et, Sanchez-Martinez, A, Hernandez-Gimenez, L, Galofre-Recasens, M, Ferrer-Vilela, I, Pérez-Sanchez, Le, Esteves, Mb, Menéndez-Moreno, A, Baz-Figueroa, C, Rosat, A, Hontoria, M, García, Na, Gracia-Roman, R, Pascua-Sole, M, Pino-Perez, O, García-Pérez, Jm, Pineño-Flores, C, Ambrona-Zafra, D, Sancho-Muriel, J, Alvarez, E, Jiménez-Rosellón, R, Daga, O, Alberca-Paramo, A, Sanchez-Garcia, S, García-Santos, E, Pareja-Ciuró, F, Olivares-Oliver, C, Navarro-Morales, L, Tamayo-López, Mj, Tinoco-González, J, García-Rivera, Co, Agua, Ia, Moreno-Suero, F, Pereira-Mosquera, E, Zerpa, C, Llacer, E, Diaz, A, Caro, A, Feliu, F, Franco, M, Escuder, J, Abellan, M, Padilla, E, Mambrilla-Herrero, S, Plua-Muniz, Kt, Bailon-Cuadrado, M, Tejero-Pintor, Fj, Choolani-Bhojwani, E, Vila-Zarate, C, Delgado-Plasencia, Lj, Ponchietti, L, Cousins, L, Busuttil, A, Baird, C, Drye, N, Brown, Od, Mansour, S, Anderson, O, Mahapatra, R, Clements, Ja, D'Souza, N, Littlehales, Dj, Tang, Am, Byrne, Be, Cunha, P, Ogbuokiri, C, Eiben, P, Gravante, G, Kho, H, Dobbs, S, Doulias, T, Ng, J, Wilson, M, Venugopal, R, Wolff, J, Akhtar, K, Walji, Hd, Tognarelli, Jm, Knight, Ka, Ansari, A, Hussaini, Sa, Wright, E, Brewer, H, Rinkoff, S, Harries, Rl, Fairfield, Cj, Abbott, T, Jackson, A, Wright, Hl, Walters, U, Carney, K, Logan, Pc, Mughal, Z, Strachan, E, Chasty, B, Ma, J, Mazzeo, C, Badii, B, Armellini, A, Grassia, M, Perin, A, Ruzzenente, A, Magnoli, M, Depalma, N, Longheu, A, Papandrea, M, Dova, L, De Prizio, M, Gusai, Gp, Di Zitti, L, Geretto, P, Azabdaftari, A, Chianese, G, Elbetti, C, Ruffolo, C, Giaccari, S, Devezas, V, Ferreira, J, Peixoto, R, Alshafei, A, Simo, V, José, H, Ugarte-Sierra, B, Salva, Ab, Gómez, N, Marinello, F, Medina-Arana, V, Vega, L, Ballester, Mm, Espina, B, Prieto-Nieto, Mi, Rodríguez, Ec, Padilla-Valverde, D, Duran-Muñoz-Cruzado, Vm., Bhangu A., Nepogodiev D., Matthews J.H., Morley G.L., Naumann D.N., Ball A., Chauhan P., Bhanderi S., Mohamed I., Glasbey J.C., Wilkin R., Drake T.M., Clements J., Blencowe N.S., Herrod P., Pata F., Frasson M., Blanco-Colino R., Soares A.S., Jain S., Amuthalingam T., Tyler R., Griffiths E.A., Pinkney T.D., Gee O., Morton D.G., Beggs A., Beral D., Bowley D., Cruickshank N., Daniels I., Griffiths E., Hornby S.T., Lund J.N., Marriott P., Singh P., Smart N.J., Speake D., Thompson C., Torkington J., Torrance A., Vohra R., Warren O., Winter D.C., Pellino G., Sgro A., Simioni A., Farina V., Podda M., Di Saverio S., Birindelli A., Pasquali S., Surg I.T., Surg P.T., Bolton W., Bradshaw C.J., Chean C.S., Harris G., Haddow J.B., Jamieson N.B., McCain S., Mason J., Milgrom D., Nana G.R., Mohamed M.N., Brien J.O., Pearce J., Rabie M., Sahnan K., Sarmah P., Skerritt C., Ghazanfar M.A., Sreedharan L., Kabwama S., Gray R.T., Kamande I.W., Nazarian S., Dar F.A., Misky A.T., Arunachalam S., Twum-Barima C.S., Mohamed I.M., Connor K.L., Coe P.O., Kosti A., Elshaer M., Colvin D.A., Charalambous M.P., Yeung K., Merker L., Morrison T., Thaventhiran A.J., Gilbert T.M., Clements J.M., Hicks G., Afshar S., Mckinley N.C., Assaf N., Hanna T., Macinnes E., Thavanesan N., Dubois A.S., Palani-Velu L.K., Tezas S., Yow L., Radwan R.W., Abdelrahman M., Lee K.A., Zarka Z.A., Mcdowall N.A., Tan C.Y., Venn M.L., Ashmore D.L., Whitehorn S.E., Golder A.M., Reddy A., Delimpalta C., Kay O.H., Shah S.M., Eiben I., Doyle C., Tudyka V., Issa E., West H., Brewer H.K., Farrow E.Z., Taylor N.S., Smart C.J., Griffiths N.P., Halkias C., Vitish-Sharma P., Knight S.R., Mowbray N.G., Olivier J.B., Lee K.J., Clement K.D., Chrastek D., Panda N., Connor M.J., Fahmy S.E., Bryan E.S., Ngu W.S., Adegbola S.O., Vaughan E.M., Stupalkowska W., Simmonds L., Malik A., Hussein A., Karim M.J., Singhal T., Ormiston R., Kung V., Rabie M.A., Park J.H., Lal N., Worku D., D'Auria M., Ang A., Orizu M., Gammeri E., Clough E., Choy C.H., Lawday S., Hann A.J., Robinson D., Wardle B.G., Mcdonnell D., Rutherford D.G., Hickey L.M., Garg A.G., Rezvani S., Bell C.R., Mahmood F., Rehman S., Donaldson G., Peleki A., Pearce L., Sharp O.L., Singh S., Thompson D.B., El-Tayar O., Hollyman M., Rupasinghe S.N., Toomey D.B., Murray M.P., Amtul N., Mersh R.J., Newton R.C., Al-Khyatt W., Stephens G.F., Abbas S.H., Iqbal M.R., Brown C.E., Renshaw S., Hureibi K.A., Pullabatla-Venkata U.P., Donohoe N.O., Myatt A., Egan R.J., Rangarajan K., Trail M., Mckay S.C., Engall N., Jerome E., Townsend D.C., Patel B.Y., Pronin S., Chandratreya N., Choong J.H., Mohamed T.M., Hudson-Peacock N.J., Manson R., Hebbar K., Mothe B.S., Weegenaar C.R., Saad M., Bowman C.R., Serventi F., Fleres F., Foppa C., Pata G., Baronio G., Pertile D., Lucchi A., Sagnotta A., Maretto I., Campagnaro T., Gatti M., Gjoni E., Roscio F., Inama M., Coccolini F., Colombo F., Avanzolini A., Aresu S., De-Manzoni-Garberini A., Merlini D.A., Chessa A., Tamini N., Mulas S., Cillara N., Coletta D., Atzeni J., Erdas E., Gallo G., Francone E., Di Gioia P., Bianchi C.L., Ferrara F., Biancafarina A., Scabini S., Marano L., Miegge A., Sasia D., Savino G., Scatizzi M., D'Amico F.E., Arcuri G.A., Gavagna L., Salamone G., Tatulli F., Goldin E., Matos M.L., Caldeira A.B., Romano J., Pereira J., Azevedo J., Azevedo J.M., Simoes J., Silva A., O'Leary D.P., Kennedy N.D., Quinn E.M., Zhang A.Y., Neary P.M., De-Marchi J.A., O'Connor B.R., Wijesundera K., Foley N.M., Wong J., Tiedt L.A., Bolger J.C., Connelly T.M., Ahmed O.S., Vigorita V., Garcia V., Arredondo J., Redondo E., Sainz B., Aldrey I., Landaluce-Olavarria A., Gomez A.A., Cordoba E., Sanchez-Fuentes M.N., Cerdan-Santacruz C., Beltran-De-Heredia J., Garcia M., Veres T., Garcia-Novoa A., Abellan A.M., Garcia-Catala L., Ruiz-Marin M., Menendez P., Roldan-Ortiz S., Navas-Cuellar J.A., Sabia D., Gomez-Rosado J.C., Navidad M.S., Caula C., Sanchez E.R., Espin-Basany E., Fernandez-Martinez D., Bravo-Gutierrez A.F., Paya-Llorente C., Dujovne P., Lima F., Soria-Aledo V., Gomez C.J., Pascual-Miguelanez I., Muinelo M., Alvarez C.M., Vargas-Pierola H.J., Vallve-Bernal M., Hidalgo-Rosas J.M., Arenal-Vera J.J., Sena-Ruiz F., Sanchez-Guillen L., Villarejo-Campos P., Tallon-Aguilar L., Garcea A., Bennett J.M., Whittaker L., Gidwani A.L., Byrnes C.K., Saunders S., Shiwani M.H., Ashraf N., Venkatasubramaniam A.K., Bevan K.E., Mcarthur D., Mustafa A.K., Griffith J.P., Blazeby J.M., Charalabopoulos A., Campbell W., Reese G., Warren O.J., Peacock M., Menzies D., Jenner D., Eardley N.J., Yoong S., Abulafi M., Avalapati H., Thompson R., Nastro P., Kochupapy R., Stubbs B.M., McIntyre R., Crozier J., Patel P.K., Pento V., Beasley W.D., Roxburgh C., Youssef H., Alexander R., Denley S., Di Franco F., Quddus A., Saha A., Hunter I., Hannay J., Velchuru V.R., Bond-Smith G., Salama Y., Bhargava A., Panagiotopoulos S.P., Watson N., Garcea G., Boddy A.P., Dunning P.G., Lloyd G., Gurjar S.V., Hill J., Andrews B., Singh A., Ruzvidzo F., Shingler G., Mahon D., Elgaddal S., Payne C.J., Shaikh I.A., Dalmia S., Nair M.S., Finch J.G., Chapple K.S., Bawa S., Watfah J., Carden C.A., Makhija R., Rao M., Sarveswaran J., Vijay V., Rekhraj S., Knight B., Siddiqui M.N., Sebastian J.F., Glen P., Vakis S., Ebied H., Rajaram R., Gray J., Mcgrath D., Faulkner G., Gopalswamy S., Varcada M., Woodward A., Williams G.L., Szentpali K., Ravindran R., Bronder C., Thaha M.A., Rate A., Shetty V.D., Rao V., Sajid M.S., Clements B., Patel R.T., Mason C., Branagan G., Maude K., Kaur G., Lyons A., Ainsworth P., Hagger R., Zadi A.Z., Maslekar S.U., Kinross J., Irukulla S., Hawkins W., Wheatstone S., Magro T., Bailey S., Marshall G., Mccullough J., Marangoni G., Leung E.L., Borg C.M., Gopinath S., Kirkby-Bott J., Yalamarthi S., Mirza S., Brett M., Ramcharan S., Pandey V., Thava B., Andreani S.M., Sahay S.J., Aravind B., Downey M., Nicol D., Whitehouse P., Sharma A., Francis N., Chitsabesan P., Stewart D.J., Norcia G.G., Cucinotta E., Cianchi F., Romario U.F., Taglietti L., Capelli P., Garulli G., Parisi A., Nitti D., Guglielmi A., Alonzo A., Scandroglio I.S., Moretto G., Ansaloni L., Pietrabissa A., Foschi D., Vettoretto N., Ercolani G., Coppola M., Colangelo E., Morandi E., Niolu P., Pala M., Coletti M., Pisanu A., Nicolosi A., Sammarco G., Berti S., Soliani P., Tonini V., Stella M., Ceccarelli G., De Nisco C., Castagnoli G., De Nardi P., Borghi F., Agresta F., Benevento A., Cantafio S., Cesari M.C., Rubbini M., Chetta G., De Marchi F., Nora M.F., Sousa H.S., Nascimento C.A., Casimiro C., Costa S.D., Rosa M.J., Carvalho N., Correia J., Gomes A.P., Hill A.D., Walsh T.N., Aremu M.A., Mulsow J., El-Masry S., Gillick J., Garvin J., Caldwell M., Mehigan B., Peirce C.B., Cooke F., Mealy K., Ruano A., Ais G., Fueyo J., Parajo A.E., Bernal-Sprekelsen J.C., Monzon-Abad J.A., Blanco F., Arroyo A., Bazan-Hinojo M.C., Ramos-Bernado M.I., Lopez-Ruiz J.A., Golda T., Julia D., Cuadrado M.M., Gomez-Abril S.A., Martinez J., Aguayo J.L., Millan M., Alvarez-Gallego M., Muinelo-Lorenzo M., Parra J.M., Munoz-Munoz E., De Chaves-Rodriguez P.G., Canovas-Moreno G., Rodriguez-Lopez M., Segura-Sampedro J.J., Garcia-Granero A., Redondo-Calvo F.J., Dyson S., Thakur D., Swords C., Siaw O., Zelazek M., Woo R., Badran A., Aruparayil N., Christopoulos P., Chambers B., O'Neill N., Long R.H., Mccaughey P., Wong M.L., Mccain R.S., Lennox-Warburton H.C., Moore C., Manektella K.M., Mcilwaine S., Rupani S., Simpson D.J., Wauchope J., Ng M., Christian L., Crone A., Sacks R., Symons N., Lazzaro A., Patil S.D., Roomi S., Silva I., Hodgson J.M., Ly C., Froud H., Patel H., Cay P., Karwal R.S., Danquah-Boateng D., Berry B., Esmail H.D., Maripi H., Bilku D., McKelvie M.A., Miller K., Maina A., Velho R., Hasan R., Clingan R., Jah S., Waite K., Jones A., Buckley-Jones S., Lecky-Thompson L., Saghir N., Mansoor S., Mistry D., Brown R., Wong A., Gurung S., Wensley F., Fleming T.A., Griggs R., Haines S., Bedoya S., Beverstock A., Johnson J., Govind G., Niaz O., Dyal A., Tokidis E., Punj S., Leusink A., Rudland I., Kelly M., Morgan R., Al-Musawi S., Lek C., Gilbert A., Gosal A., Mahoney R., Parwaiz I., Mitchard M.J., Ribeiro B., Merai H., Dean E.A., Khan S., Baginski A., Mann C., Foers W., Jones L., Woodward B., Mcwhirter D.M., Thomas A.T., Gilbert T.G., Weatherburn L.W., Pilkington J.P., Cameron F.C., Clements J.D., Mccann C., Davidson S., Hackney L., Clements J.S., Martin A., Du D.T., Shakoor Z., Yen S.K., Adnan M., Ranathunga S., Sana S., Tay Y.H., Chin M.Y., Gillespie M., Brown A.G., Campbell U., Chatzikonstantinou M., Mahendran B., Flack T., Chowdhary M., Lim J.M., Whiteman E., Shepherd J.A., Pedder A., Siggens K.L., Lai C.W., Morrison-Jones V., Hayat Z., Nehikhare I., Macleod C., Quinn H.C., Brown A., Neagle G., Chok S.M., Carrano F.M., Abbassi O.A., Divekar G.A., Halmer S., Adams R.E., Davies P.L., Wong S.Y., Amarasinghe R., Tague L.E., Jones E., Singh J., Boza K., Kelly S.D., Morrison F., Chan W.H., Wilson E.J., Awokoya O.O., Griffiths S.N., Kirkham E.N., Cotton A.E., Adimonye A., Leighton P.A., Abdelrahman A., Cartwright H., Gates Z., Miguras M., Khan K., Louw C., Grove T., Badenoch T., Mckeon J., Wood C.S., Leitch R.P., Sgardelis P., Perera M.I., Nagarajan D., Malam Y., Theodoropoulou K., Rajagopal S., Kaptanis S., Popova D., Olagbaiye O., Tayeh S., Rigby S., Harris M.P., Ren K.Z., Liaw G., Zhou S., White F., Marshall C.M., Mitchell J.H., Anderson D.J., Kanakala V., Hollingsworth A., Paramasevon K.R., Milward J., Ahmed S., Fanibi B.F., Ferguson N., Dickson E.A., Shaw A.V., Dixon F., Morrish S., Dandy R., Fooks P., Sharma P., Islam N., Tabain V., Keegan R., Ahel J., Alhammali T., Graveston J., Balai E.J., Rothnie K., Pankin G.P., Eiben I.E., Jackson N.J., Dhar M., Nash D., Dharamavaram S., Seth M., Chowdhury F., Rezacova M., Seneviratne N., Turner E.J., Currow C., Isherwood J.D., Hobson B.M., Lui D.H., Rodger V., Ting N., Photiou D., Taze D., Lodhia S., Earnshaw L., Kumar K., Neale A., Bastianpillai J., Cipparrone M., Barrie A., Nash Z., Anandan L., Tailor K., Vinnicombe Z., Krivan S., Kuo R., Giorga A., Habib H., Malik K., Bogdan M., Mahon-Daly F.P., Athersmith M.J., Strange J.A., Wheeler C., Summerfield L., Khaw R.A., Ashour O., Iosif E., Fadel M., Gopalakrishnan K., Orme N., Williams S., Rashid M., Sultana A., Patel N., Pearson R., Yasin T., Bevan V., Al-Sarireh B., Brown M., Mohd N., Howie E.E., Poudevigne M., Paget C., Rallage H., Chui K., Fawzi F., Layman S., Okorocha E., Jama G.M., Orawiec P., Kouli O., Hassane A., Kilkenny J., Devine A.A., Laurenson M., Slezak I., Barker T., Lau E., Limbada M., O'Brien J., Weaver J., Hajibandeh S., Shah J., Mansour M.M., Malik S.N., Davis S., Trew F., Bandyopadhyay S.K., Dart K., Guru-Naidu S., Callan R., Nair M.K., Alani M., Sezen E., Salim S., Shurlock J., Siddique K., Forouzanfar A., Brews R., Acharya A., Jain A., Tozer P.J., Warusavitarne J., Emslie K.M., Collier-Wakefield O., Sivaloganathan P., Dobson C., Elseedawy M., McNally L., Williams M., Motiwala F.H., Choi S., Asmadi A.A., Burnside D., Everden A., Suriyakumar S., Sandu L., Kent D.A., Bowen J., Long P., Khair A., Shah K., Phelan L., Pierre R., Dhari A.A., Hoff M., Nickson S., Setshwaelo T., Chalk A., Parkola M.J., Harlinska A., Chan T., Dudek J.G., Rolph R., Allen M., Pollard H., Gormely R., Finlayson H., Ljungqvist G., Peponis C., Rahman M., Dhesi S., Arshad F., Faris A.R., Sooriyamoorthy T., Springate E.L., Barnieh W., Patel A.S., Siddiqui Z.A., Chishti I.A., Ayube-Brown J., Rabie M.R., Blake L., Yardimci E., Nagendram S., Neophytou G.I., Henderson L., Farhan-Alanie M., Kong C.Y., Ghazala R., Evans J., Hussain N., Kabir M., Hraishawi I., Cox M., Bailey J.A., Muhibullah N., Yanni F., Stevenson R., Nair A., Murphy C., Mcgucken O., Pandya R., Bowerman H., Lafaurie G., Van Boxel G.I., Shanmugarajah K., Maragouthakis D., Hanif Z., Evans J.D., Yoganathan S., Richardson T.D., Cook V., Clark G.L., Rigney B., O'Neill E., Guliani J., Chan D., Harper F., Sian T., Boereboom C., Blackwell J., Hardy E., Boyd-Carson H., Couch D.G., Barter C.A., Thoukididou S.N., Hatt J.R., Jones C.S., Dean S., Rajaretnam N., Masood M., Thakral N., Griffith D., Doherty C., Longshaw A., Peprah D., Mathew G., Hook A., Vance-Daniel J., Ibrahim Y., Walters K.J., Whewell H.E., Sherif M.A., Mckenna M., O'Sullivan D., Woodrow C., Gill S., Johnstone A., Gentry R., Irwin R., Forgie A., Welsh S., Ivey P., Bullivant J.K., English W.J., Osterberg A., Morowala A., Al-Faham Z., Islam S., Tan E., Sadek S., Sihra N., Shrestha D., Chong B., Nadeem A., Fasuyi J.A., Patel M.M., Daureeawoo R., Okekunle B., Cheruvu M., Mazumdar E., Hussain A., Patel C., Mcquaid M., Banks A., Robinson A., Khan M.S., Riaz W., Verroiotou M., Cohen J.A., Kouroumpas E., Ghaffari I., Moradzadeh J., Kamal M., Gulamhussein M., Gaines E., Ghatorae S., Clark S., Savill A., Hutchinson B., Chapman J., Wu F., Creasy W., Raymond M., Grosvenor S., Odeh A., Malik Y., Bansal H., Grant C., Raofi A., Ahmed B., Mai D., Souter J., Hamelmann R.N., Ikram S., Durbacz M., Gilliland N., Salem A., Chudek D., Ladwa N., Storey R., Fontaine C., Toomey D., Miller B., Oakey M., Smoker H., Chapman S.J., O'Hagan S.C., Tahir W., Wilcox G., Ahmad A., Akram F., Baddams T.S., Boshier P.R., Fehervari M., Easdon S., Ilozue T., Adam M.E., Jokhan S., Foster A., Nambiar K., Bohra P., Janardanan S., Shanmuganathan V., Maqboul F., Ettles C., Wardle S.D., Martinou E., Khasria A., Bagga R., Motter D., Mundkur N., Pan Y., Akbari K., Farrell S.M., Rahim A., Gummaraju A., Mahmoud A., Akinsola O., Smallcombe N., Tarazi M., Hanley C., Campbell U.M., Franklin D., Davidson J.R., Raza S.S., Krishnamoorthy A., Rajjoub Y., Ali M., Seddon T.C., Payne R.E., Das A., Martin L.M., Naismith K.N., Venkata U.P., Manda V.M., Burns K.M., Huang J., Samuel M., Docherty J.A., Cheah W.L., Ooi R., Nyeko-Lacek M., Marsh L., Prideaux A., Li C.H., Poacher A., Lee M., Muzaffar M., Kara A., Walsh E., Sunter H., Roth N., Roy C., Mcmorran D., Turnbull A., Layton G.R., Archer J.E., Yang P., Douka E., Amin V., Borghol K., Blackford O.D., Bond S., Baker B., Mohamed W.O., Williams R., Garnham J., Robb H.D., Allington J., Cloney L., Tamborska A., Kalia K., Fung E., Johnston Z., Lynch L., Christides A., Tan H.L., Cynthia G., Tsang B., Rossi C., Kaubrys M., Al-Khafaji N., Jenkins M., Peiris G.B., Gunning S., Nimako E., Pandya D., Hever P., Amayo A., Bull C., Clements C., Al-Sheikh M., Savioli F., Long M., Horsfield E., Robertson C., Ogboru S., Mcilwrath A.C., Bell J., Limb C., Obeid N., Rich J.E., Balasubramaniam A., Mashar R., Taylor M., Bruce J.S., Dennison G., Curtis N.J., Ezerska E., Ellis B., Wiggill S., Tee A., Ng S., Carder C., Abdelwahed A., Chandler S.B., Tinsley B.J., Finotti E., Occhioni G., Cossu F., Vulcano I., Viscosi F., Michelini M., Compagnoni B., Sepe C., Isolani S.M., Regina G., Alagna V., Martorelli G., Gabbianelli C., Moroni P., Zuin M., Conci S., Lazzari G., Costamagna D., Zurleni T.Z., Altomare M.A., Desiderio J., Di Cintio A., Gemini A., Trastulli S., Viviani E., Tomasoni M., Montori G., Harder G., Argenti F., Malabarba S., Checcacci P., Montanelli P., Guerra F., Skalamera I., Staderini F., Grandi S., Nelli T., Coratti F., Sorrentino L., Maffioli A., Cavallo D., Bondurri A., Groppo G., Curti R., Solaini L., Xidas A., Manias T., Delogu D., Vacca A., Solinas L., Corbellini C., Fiore L., Nigro A., Santurro L., Angrisani M., Sparta C., Lorettu A., Mura F.A., Ruggiu G.V., Pirari P.F., Pau R., Melis M., Piu F., Patti S., Deserra A., Angelieri D., Del Basso C., Rossi D., Iannone I., De Padua C., Giubilo C., Falaschi F., Cirillo B., Gordini L., Podda F., Sanna S., Saba A., Poillucci G., Pinna E., Messina A., Sena G., Cardona R., De Luca E., Sacco R., Vescio G., Ammendola M., Romano R., Bianco A., Bonfante P., D'Ambra L., Feleppa C., Gennai A., Lizzi V., Moggia E., Imperatore M., Bolzon S., Belvedere A., Amaducci E., Ripoli M.C., Segalini E., Cervellera M., Vaccari S., Eretta C.O., O'Neill R., Llewelyn O., Jones N., Clerici F., Ballabio M., Andolfi E., Angelini M., Fontani A., Miranda E., Scricciolo M., Provenza G., Pellicano G.A., Pulighe F., Argenio G., Melis A., Balestra F., Anania M., Cruccu A., Massaiu C., Murru M.L., Martino A., Luzzi A.P., La Valle G., Chillitupa C.Z., Bartoli A., Conti D., Spaziani A., Bellochi R., Listorti C., Salandini M.C., Carlucci M., Tenconi S.M., Cannavo M., Marano A., Giuffrida M.C., Cannata G., Pellegrino L., Giraudo G., Baraghini M., Garzi A., Giudicissi R., Zalla T., Romoli L., Vannucchi A., Giani I., Feroci F., Calussi M., Ribaudo M., Fiorot A., Stecca T., Nistri C., Fornasier C., Valiani S.V., Brunelli D.B., Evoli L.E., Giuliani N.G., Contine A.C., Renzi C.R., Feo C.V., Anania G., Carcoforo P., Aisoni F., Licari L., Tutino R., Cocorullo G., Silvestri V., De Marco P., Fontana T., Orlando G., Falco N., Baseggio M., Napetti S., Mella A., Rossi G.M., Chimetto A., Cosci M., Bonomo M., Scialandrone G., Chetta N., Carvalho L.C., Magalhaes J.S., Pereira A.M., Fernandes C., Fareleira A., Goncalves D., Pais M., Pereira A., Resende F.M., Correia D., Cardoso D., Tojal A., Santos S.C., Barbosa L., Louro H.C., Bairos F., Martins F.M., Messias F.M., Ferreira M.S., Borges F.C., Botelho P., Lima M., Valente P.M., Joao A.A., Guimaraes J.M., Rocha R., Nogueira S.T., Kabir U., Wong C., Rahmani L.S., Tan S., Chng S., Jasinski B., Cheng S.A., Mardhiah S., McGlynn K., Hannan E., Burke J., Haveliwala Z., O'Neill M., Boland M., Hayes C., Fox A., Zaborowski A., Mitru R.M., Mc-Dermott A., Coyle D., Stoica I., McMahon S.V., Laughlin D.M., Kannegieser-Bailey M., Murphy R., Muntean A., Shet S., Thomas L., De Freitas S., Quill S., Aljorfi A., Soh B., Law J.J., Hartnett J., Jansen T., Gilgan J., Jung J., Scanlon K., Szucs A., Ahern D.P., Redmond A.E., Edwards S.E., Manoharan P., Brennan S., Abdelgadir A.M., Mckevitt K.L., Zarog M.A., Ahmed G., Bukhari W., Ahad A., Paniagua M., Samartin C., Primo J.C., Garrido L., Lopez M., Rufo E., Trostchansky I., Rodriguez L., Infante H., Acosta A., Cremades P., Cidoncha A., Olmos V., Oliva I., Santamaria C., Cavero A., Calvo H., Suero C.A., Maderuelo V.M., Galvez P., Hernando A., Eguaras I., Recreo A.C., Garcia-Carrero M., Moreda R., De Andres U., Del Pozo E., Calvo M., Moratalla C.N., Ronda R.N., Contreras R.G., De Burgos C.B., Cortes G.V., Martinez C.C., Agudo A.R., Soriano J.T., Ramos X.H., Echazarreta E., Elia M., Hernaez A., Sanchez L., Vallejo-Bernad C., Oliver J.R., Sanchez-Rubio M., Kalviainen H.K., Genzor S., Gonzalez-Nicolas T., Puerta E., Laviano E., Gimenez T., Ferminan A., Muriel-Alvarez P., Sierra-Granon J.E., Escoll-Rufino J., Cuello-Guzman E., Mestres-Petit N., Merichal-Resina M., Pinillos-Somalo A., Gomez-Carmona Z., Vazquez-Fernandez A.P., Trujillo-Diaz J.J., Couso J.R., Fernandez M.D., Riera E., Espinosa J., Carral-Freire M., Martinez-Almeida R., Santarrufina-Martinez S., Sebastian-Tomas J.C., Gonzalvez-Guardiola P., Fernandez E.C., Mozo A.S., Stoyanov T.I., Santamaria P.C., Grimaldo E.G., Fernandez-Candela A., Curtis-Martinez C., Del-Valle-Ruiz S.R., Sanchez-Cifuentes A., Ramirez-Faraco M., Lopez A.F., Leon C., Kumar S., Fornell-Ariza M., Ayllon-Gamez S., Pena-Barturen C., Ojea-Ruiz-Yherla L., Saavedra-Chacon M., Perez-Calvo J., Gomez-Facundo H., Riba-Combatti L., Manas O.C., De-Soto-Cardenal B., De-La-Herranz-Guerrero P., Dominguez-Sanchez C., Gamero-Huaman J.C., Suarez-Cabrera A., Ramirez-Redondo A.A., Lara-Fernandez Y., Bascuas-Rodrigo B., Lopez-Duran B.L., Pigem A., Gil J., Salvador H., Planellas P., Farres R., Caballero A., Arnau M., Tapiolas I., Ridaura N., Roncero L.S., Collado-Roura F., Fijo L.M., Cormenzana O.B., Vinas N.L., Grifell M.S., Prats M.A., Torrado A.A., Sanz-Navarro S., Contreras-Saiz E., Solar-Garcia L., Moreno-Gijon M., Suarez-Sanchez A., Diaz-Vico T., Rodicio-Miravalles J.L., Garcia-Gutierrez C., Pila U., Melone S., Martin-Prieto L., Rojo J.A., Gonzalez M., Zorrilla L., Garcia-Marin J.A., Baeza-Murcia M., Pellicer-Franco E., Jimenez-Ballester M.A., Asensio-Gomez L., Gortazar-De-Las-Casas S., Guevara-Martinez J., Ramirez L., Verea S., Anguita F., Navarro G., Criado ADC., Lara M.C., Martinez E.T., Sanchez-Martinez A., Hernandez-Gimenez L., Galofre-Recasens M., Ferrer-Vilela I., Perez-Sanchez L.E., Esteves M.B., Menendez-Moreno A., Baz-Figueroa C., Rosat A., Hontoria M.S., Garcia N.A., Gracia-Roman R., Pascua-Sole M., Pino-Perez O., Garcia-Perez J.M., Pineno-Flores C., Ambrona-Zafra D., Sancho-Muriel J., Alvarez E., Jimenez-Rosellon R., Daga O., Alberca-Paramo A., Sanchez-Garcia S., Garcia-Santos E., Pareja-Ciuro F., Olivares-Oliver C., Navarro-Morales L., Tamayo-Lopez M.J., Tinoco-Gonzalez J., Garcia-Rivera C.O., Agua I.A., Moreno-Suero F., Pereira-Mosquera E., Zerpa C., Llacer E., Diaz A., Caro A., Feliu F., Franco M., Escuder J., Abellan M., Padilla E., Mambrilla-Herrero S., Plua-Muniz K.T., Bailon-Cuadrado M., Tejero-Pintor F.J., Choolani-Bhojwani E., Vila-Zarate C., Delgado-Plasencia L.J., Ponchietti L., Cousins L., Busuttil A., Baird C., Drye N., Brown O.D., Mansour S., Anderson O., Mahapatra R., Clements J.A., D'Souza N., Littlehales D.J., Tang A.M., Byrne B.E., Cunha P., Ogbuokiri C., Eiben P., Gravante G., Kho H., Dobbs S., Doulias T., Ng J., Wilson M., Venugopal R., Wolff J., Akhtar K., Walji H.D., Tognarelli J.M., Knight K.A., Ansari A., Hussaini S.A., Wright E., Brewer H., Rinkoff S., Harries R.L., Fairfield C.J., Abbott T., Jackson A., Wright H.L., Walters U., Carney K., Logan P.C., Mughal Z., Strachan E., Chasty B., Ma J., Mazzeo C., Badii B., Armellini A., Grassia M., Perin A., Ruzzenente A., Magnoli M., Depalma N., Longheu A., Papandrea M., Dova L., De Prizio M., Gusai G.P., Di Zitti L., Geretto P., Azabdaftari A., Chianese G., Elbetti C., Ruffolo C., Giaccari S., Devezas V., Ferreira J.S., Peixoto R., Alshafei A., Simo V., Jose H.S., Ugarte-Sierra B., Salva A.B., Gomez N., Marinello F., Medina-Arana V., Vega L., Ballester M.M., Espina B., Prieto-Nieto M.I., Rodriguez E.C., Padilla-Valverde D., and Duran-Munoz-Cruzado V.M.
Subjects: Adult, humanos, Decision Making, Risk Assessment, NO, apendicectomía, apendicitis, evaluación de riesgos, Appendectomy, Humans, hospital, General, collaborative, LS7_4, right iliac fossa, appendicitis, emergency service, Original Articles, adulto, Appendicitis, adult, appendectomy, humans, risk assessment, decision making, Lower GI, Original Article, appendicitis, prediction models, right iliac fossa pain, Emergency Service, Hospital, toma de decisión
Abstract: Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P, Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making were identified by identifying UK adults at low risk of appendicitis. An online calculator is available (http://appy-risk.org). WCC, white cell count; CRP, C‐reactive protein; AIRS, Appendicitis Inflammatory Response Score; AAS, Adult Appendicitis Score. Important differences between men and women
Published: 2019

7. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author: Guerra, Francesco, primary, Petrelli, Filippo, additional, Greco, Paola Antonella, additional, Sisti, Valerio, additional, Catarci, Marco, additional, Montalti, Roberto, additional, Patriti, Alberto, additional, Alagna, V., additional, Amodio, P., additional, Anania, G., additional, Angeloni, R., additional, Arici, E., additional, Baiocchi, G., additional, Baraghini, M., additional, Benedetti, M., additional, Bertocchi, E., additional, Borghi, F., additional, Brisinda, G., additional, Campagnacci, R., additional, Capolupo, G.T., additional, Caricato, M., additional, Carrara, A., additional, Ceccaroni, M., additional, Chiarello, M.M., additional, Cianflocca, D., additional, Ciano, P., additional, Cicconi, S., additional, Clementi, M., additional, Delrio, P., additional, Di Cesare, T., additional, Di Marco, C., additional, Falsetto, A., additional, Garulli, G., additional, Guadagni, S., additional, Guercioni, G., additional, Lambertini, M., additional, Liverani, A., additional, Longo, G., additional, Lucchi, A., additional, Luzzi, A.P., additional, Macarone Palmieri, R., additional, Mancini, S., additional, Marini, P., additional, Marsanic, P., additional, Martino, A., additional, Martorelli, G., additional, Marziali, I., additional, Maurizi, A., additional, Migliore, M., additional, Molfino, S., additional, Motter, M., additional, Muratore, A., additional, Pace, U., additional, Pandolfini, L., additional, Pavanello, M., additional, Pirozzi, F., additional, Ruffo, G., additional, Ruggeri, B., additional, Sagnotta, A., additional, Santoni, S., additional, Scabini, S., additional, Scatizzi, M., additional, Sciuto, A., additional, Sica, G., additional, Tirone, G., additional, Tomassini, F., additional, Vettoretto, N., additional, and Zigiotto, D., additional
Published: 2021
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8. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author: Guerra, Paola Ofelia Francesca, Petrelli, F., Greco, P. A., Sisti, V., Catarci, Marco, Montalti, R., Patriti, A., Alagna, V., Amodio, P., Anania, G., Angeloni, Riccardo, Arici, E., Baiocchi, G., Baraghini, M., Benedetti, Marta, Bertocchi, E., Borghi, F., Brisinda, Giuseppe, Campagnacci, R., Capolupo, G. T., Caricato, M., Carrara, A., Ceccaroni, Marcello, Chiarello, M. M., Cianflocca, D., Ciano, P., Cicconi, S., Clementi, Maria Elisabetta, Delrio, P., Di Cesare, Tiziana, Di Marco, C., Falsetto, A., Garulli, G., Guadagni, S., Guercioni, G., Lambertini, M., Liverani, Antonio Maria Nicola, Longo, G., Lucchi, A., Luzzi, A. P., Macarone Palmieri, Raffaele, Mancini, S., Marini, P., Marsanic, P., Martino, A., Martorelli, G., Marziali, I., Maurizi, A., Migliore, M., Molfino, S., Motter, M., Muratore, A., Pace, U., Pandolfini, L., Pavanello, M., Pirozzi, F., Ruffo, G., Ruggeri, B., Sagnotta, A., Santoni, S., Scabini, S., Scatizzi, M., Sciuto, A., Sica, Gigliola, Tirone, G., Tomassini, F., Vettoretto, N., Zigiotto, D., Guerra F., Catarci M., Angeloni R., Benedetti M., Brisinda G. (ORCID:0000-0001-8820-9471), Ceccaroni M., Clementi M., Di Cesare T., Liverani A., Macarone Palmieri R., Sica G. (ORCID:0000-0002-7231-9139), Guerra, Paola Ofelia Francesca, Petrelli, F., Greco, P. A., Sisti, V., Catarci, Marco, Montalti, R., Patriti, A., Alagna, V., Amodio, P., Anania, G., Angeloni, Riccardo, Arici, E., Baiocchi, G., Baraghini, M., Benedetti, Marta, Bertocchi, E., Borghi, F., Brisinda, Giuseppe, Campagnacci, R., Capolupo, G. T., Caricato, M., Carrara, A., Ceccaroni, Marcello, Chiarello, M. M., Cianflocca, D., Ciano, P., Cicconi, S., Clementi, Maria Elisabetta, Delrio, P., Di Cesare, Tiziana, Di Marco, C., Falsetto, A., Garulli, G., Guadagni, S., Guercioni, G., Lambertini, M., Liverani, Antonio Maria Nicola, Longo, G., Lucchi, A., Luzzi, A. P., Macarone Palmieri, Raffaele, Mancini, S., Marini, P., Marsanic, P., Martino, A., Martorelli, G., Marziali, I., Maurizi, A., Migliore, M., Molfino, S., Motter, M., Muratore, A., Pace, U., Pandolfini, L., Pavanello, M., Pirozzi, F., Ruffo, G., Ruggeri, B., Sagnotta, A., Santoni, S., Scabini, S., Scatizzi, M., Sciuto, A., Sica, Gigliola, Tirone, G., Tomassini, F., Vettoretto, N., Zigiotto, D., Guerra F., Catarci M., Angeloni R., Benedetti M., Brisinda G. (ORCID:0000-0001-8820-9471), Ceccaroni M., Clementi M., Di Cesare T., Liverani A., Macarone Palmieri R., and Sica G. (ORCID:0000-0002-7231-9139)
Abstract: Introduction: how best to manage patients with colorectal cancer and synchronous liver metastasis is still controversial, with specific concerns of increased risk of postoperative complications following combined resection. We aimed at analyzing the influence of combined liver resection on the risk of anastomotic leak (AL) following colorectal resection. Methods: we reviewed the iCral prospectively maintained database to compare the relative risk of AL of patients undergoing colorectal resection for cancer to that of patients receiving simultaneous liver and colorectal resection for cancer with isolated hepatic metastases. The incidence of AL was the primary outcome of the analysis. Perioperative details and postoperative complications were also appraised. Results: out of a total of 996 patients who underwent colorectal resection for cancer, 206 receiving isolated colorectal resection were compared with a matched group of 53 patients undergoing simultaneous liver and colorectal resection. Combined surgery had greater operative time and resulted in longer postoperative hospitalization compared to colorectal resection alone. The proportion of overall morbidity following combined resection was significantly higher than after isolated colorectal resection (56.6% vs. 37.9%, p = 0.021). Overall, the two groups of patients did not differ neither on the rate of major postoperative complications, nor in terms of AL (9.4% vs. 6.3%, p = 0.381). At specific multivariate analysis, the duration of surgery was the only risk factor independently associated with the likelihood of AL. Conclusions: combining hepatic with colorectal resection for the treatment of synchronous liver metastasis from colorectal cancer does not increase significantly the incidence of AL.
Published: 2021

9. Technical Solutions for Venous Outflow Reconstruction in Damaged Liver Grafts During Procurement: Case Reports

Author: Nicolini, D., di Francesco, F., Cautero, N., De Luca, S., Vecchi, A., Garelli, P., Martorelli, G., Vincenzi, P., Gentili, M., Baccarani, U., Adani, G.L., and Risaliti, A.
Published: 2008
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10. Le variazioni della Merula torquata (Naum.)

Author: Martorelli, G and BioStor
Published: 1910

11. Peritoneal Leiomyosarcoma in a Kidney Transplant Patient: A Case Report

Author: Cautero, N., De Luca, S., Vecchi, A., Garelli, P., Nicolini, D., Martorelli, G., Frascà, G.M., Gaffi, G., Taruscia, D., Bearzi, I., Adani, G., and Risaliti, A.
Published: 2007
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12. F-29 Transarterial chemoembolization (TACE) with doxorubicin-eluting-bead versus conventional TACE in patients listed for liver transplantation: impact on tumor necrosis and post transplant disease-free survival

Author: Nicolini, D., primary, Baroni, G. Svegliati, additional, Candelari, R., additional, Faraci, M.G., additional, Gentili, M., additional, Vincenzi, P., additional, Martorelli, G., additional, Coletta, M., additional, Federici, A., additional, Mincarelli, C., additional, Mandolesi, A., additional, Mocchegiani, F., additional, Vecchi, A., additional, Vivarelli, M., additional, and Risaliti, A., additional
Published: 2012
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13. Early diagnosis of anastomotic leakage after colorectal surgery by the dutch leakage score, serum procalcitonin and serum c-reactive protein: Study protocol of a prospective multicentre observational study by the Italian ColoRectal anastomotic leakage (iCral) study group

Author: Benedetti, M., Ciano, P., Pergolini, I., Ciotti, S., Guercioni, G., Ruffo, G., Borghi, F., Patriti, A., Delrio, P., Scatizzi, M., Mancini, S., Garulli, G., Carrara, A., Pirozzi, F., Scabini, S., Liverani, A., Baiocchi, G., Campagnacci, R., Muratore, A., Longo, G., Caricato, M., Palmieri, R. M., Vettoretto, N., Marcello Ceccaroni, Guadagni, S., Bertocchi, E., Cianflocca, D., Lambertini, M., Pace, U., Baraghinl, M., Pandolfini, L., Angeloni, R., Lucchi, A., Martorelli, G., Tirone, G., Motter, M., Sciuto, A., Martino, A., Luzzi, A. P., Cesare, T. D., Molfino, S., Maurizi, A., Marsanic, P., Tomassini, F., Santoni, S., Capolupo, G. T., Amodio, P., Arici, E., Clementi, M., Ruggeri, B., and Catarci, M.
Subjects: Colon, Rectum, Anastomotic leakage, Colorectal surgery, Multicenter study, Prospective observational study, Study protocol, Anastomotic Leak, Leukocyte Count, C-Reactive Protein, Early Diagnosis, Elective Surgical Procedures, Risk Factors, Sample Size, Outcome Assessment, Health Care, Surgical Wound Dehiscence, Humans, Prospective Studies, Procalcitonin, Biomarkers
Abstract: Anastomotic leakage (AL) is a dreaded major complication after colorectal surgery. There is no uniform definition of anastomotic dehiscence and leak. Over the years many risk factors have been identified (distance of anastomosis from anal verge, gender, BMI, ASA score) but none of these allows an early diagnosis of AL. The DUtch LeaKage (DULK) score, C reactive protein (CRP) and procalcitonin (PCT) have been identified as early predictors for anastomotic leakage starting from postoperative day (POD) 2-3. The study was designed to prospectively evaluate AL rates after colorectal resections, in order to give a definite answer to the need for clear risk factors, and testing the diagnostic yeld of DULK score and of laboratory markers. Methods and analysis. A prospective enrollment for all patients undergoing elective colorectal surgery with anastomosis carried out from September 2017 to September 2018 in 19 Italian surgical centers.preoperative risk factors of anastomotic leakage; operative parameters; leukocyte count, serum CRP, serum PCT and DULK score assessment on POD 2 and 3. Primary endpoint is AL; secondary endpoints are minor and major complications according to Clavien-Dindo classification; morbidity and mortality rates; readmission and reoperation rates, length of postoperative hospital stay (Retrospectively registered at ClinicalTrials.gov Identifier: NCT03560180, on June 18, 2018). Ethics. The ethics committee of the "Comitato Etico Regionale delle Marche - C.E.R.M." reviewed and approved this study protocol on September 7, 2017 (protocol no. 2017-0244-AS). All the participating centers submitted the protocol and obtained authorization from the local Institutional Review Board.

14. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author: C. Di Marco, Gianluca Guercioni, G. Anania, Antonio Sciuto, Felice Pirozzi, P. Marini, Stefano Scabini, Marcello Ceccaroni, Ugo Pace, M. Pavanello, Alessandro Carrara, Elisa Arici, Federico Tomassini, Antonio Martino, Riccardo Angeloni, Alberto Patriti, B. Ruggeri, Lorenzo Pandolfini, A. Sagnotta, Marco Scatizzi, Elisa Bertocchi, R. Macarone Palmieri, Simone Cicconi, Angela Maurizi, D. Zigiotto, Marco Catarci, Gian Luca Baiocchi, G. Tirone, Paolo Delrio, Felice Borghi, Sarah Molfino, Marco Migliore, G. Brisinda, T. di Cesare, Stefano Mancini, M. Clementi, Paolo Ciano, G. Sica, Michele Motter, Vincenzo Alagna, Roberto Campagnacci, Simone Santoni, Andrea Pierre Luzzi, Giacomo Martorelli, Nereo Vettoretto, Andrea Muratore, Desiree Cianflocca, Maddalena Baraghini, S. Guadagni, M.M. Chiarello, Andrea Lucchi, Andrea Liverani, Valerio Sisti, Graziano Longo, Filippo Petrelli, Gianluca Garulli, Michele Benedetti, M. Lambertini, Pietro Maria Amodio, A. Falsetto, Francesco Guerra, Gabriella Teresa Capolupo, Paola Antonella Greco, Roberto Montalti, P. Marsanic, Marco Caricato, Giacomo Ruffo, Irene Marziali, Guerra, F., Petrelli, F., Greco, P. A., Sisti, V., Catarci, M., Montalti, R., Patriti, A., Alagna, V., Amodio, P., Anania, G., Angeloni, R., Arici, E., Baiocchi, G., Baraghini, M., Benedetti, M., Bertocchi, E., Borghi, F., Brisinda, G., Campagnacci, R., Capolupo, G. T., Caricato, M., Carrara, A., Ceccaroni, M., Chiarello, M. M., Cianflocca, D., Ciano, P., Cicconi, S., Clementi, M., Delrio, P., Di Cesare, T., Di Marco, C., Falsetto, A., Garulli, G., Guadagni, S., Guercioni, G., Lambertini, M., Liverani, A., Longo, G., Lucchi, A., Luzzi, A. P., Macarone Palmieri, R., Mancini, S., Marini, P., Marsanic, P., Martino, A., Martorelli, G., Marziali, I., Maurizi, A., Migliore, M., Molfino, S., Motter, M., Muratore, A., Pace, U., Pandolfini, L., Pavanello, M., Pirozzi, F., Ruffo, G., Ruggeri, B., Sagnotta, A., Santoni, S., Scabini, S., Scatizzi, M., Sciuto, A., Sica, G., Tirone, G., Tomassini, F., Vettoretto, N., and Zigiotto, D.
Subjects: Male, medicine.medical_specialty, Colorectal cancer, Settore MED/18 - CHIRURGIA GENERALE, Anastomotic Leak, 030230 surgery, Anastomosis, NO, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Medicine, Hepatectomy, Humans, Risk factor, Propensity Score, Colectomy, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Incidence, Liver Neoplasms, Simultaneous resection, Cancer, General Medicine, Perioperative, Middle Aged, medicine.disease, Surgery, Settore MED/18, Oncology, Elective Surgical Procedures, 030220 oncology & carcinogenesis, Relative risk, Propensity score matching, Female, Synchronous colorectal liver metastasis, business, Colorectal Neoplasms
Abstract: Introduction how best to manage patients with colorectal cancer and synchronous liver metastasis is still controversial, with specific concerns of increased risk of postoperative complications following combined resection. We aimed at analyzing the influence of combined liver resection on the risk of anastomotic leak (AL) following colorectal resection. Methods we reviewed the iCral prospectively maintained database to compare the relative risk of AL of patients undergoing colorectal resection for cancer to that of patients receiving simultaneous liver and colorectal resection for cancer with isolated hepatic metastases. The incidence of AL was the primary outcome of the analysis. Perioperative details and postoperative complications were also appraised. Results out of a total of 996 patients who underwent colorectal resection for cancer, 206 receiving isolated colorectal resection were compared with a matched group of 53 patients undergoing simultaneous liver and colorectal resection. Combined surgery had greater operative time and resulted in longer postoperative hospitalization compared to colorectal resection alone. The proportion of overall morbidity following combined resection was significantly higher than after isolated colorectal resection (56.6% vs. 37.9%, p = 0.021). Overall, the two groups of patients did not differ neither on the rate of major postoperative complications, nor in terms of AL (9.4% vs. 6.3%, p = 0.381). At specific multivariate analysis, the duration of surgery was the only risk factor independently associated with the likelihood of AL. Conclusions combining hepatic with colorectal resection for the treatment of synchronous liver metastasis from colorectal cancer does not increase significantly the incidence of AL.
Published: 2021

15. Management and 1-year outcomes of anastomotic leakage after elective colorectal surgery.

Author: Borghi F, Migliore M, Cianflocca D, Ruffo G, Patriti A, Delrio P, Scatizzi M, Mancini S, Garulli G, Lucchi A, Carrara A, Pirozzi F, Scabini S, Liverani A, Baiocchi G, Campagnacci R, Muratore A, Longo G, Caricato M, Macarone Palmieri R, Vettoretto N, Ciano P, Benedetti M, Bertocchi E, Ceccaroni M, Pace U, Pandolfini L, Sagnotta A, Pirrera B, Alagna V, Martorelli G, Tirone G, Motter M, Sciuto A, Martino A, Scarinci A, Molfino S, Maurizi A, Marsanic P, Tomassini F, Santoni S, Capolupo GT, Amodio P, Arici E, Cicconi S, Marziali I, Guercioni G, and Catarci M
Subjects: Anastomosis, Surgical adverse effects, Anastomotic Leak etiology, Anastomotic Leak surgery, Humans, Reoperation, Colorectal Surgery adverse effects, Digestive System Surgical Procedures
Abstract: Purpose: To analyze different types of management and one-year outcomes of anastomotic leakage (AL) after elective colorectal resection., Methods: All patients with anastomotic leakage after elective colorectal surgery with anastomosis (76/1,546; 4.9%), with the exclusion of cases with proximal diverting stoma, were followed-up for at least one year. Primary endpoints were as follows: composite outcome of one-year mortality and/or unplanned intensive care unit (ICU) admission and additional morbidity rates. Secondary endpoints were as follows: length of stay (LOS), one-year persistent stoma rate, and rate of return to intended oncologic therapy (RIOT)., Results: One-year mortality rate was 10.5% and unplanned ICU admission rate was 30.3%. Risk factors of the composite outcome included age (aOR = 1.08 per 1-year increase, p = 0.002) and anastomotic breakdown with end stoma at reoperation (aOR = 2.77, p = 0.007). Additional morbidity rate was 52.6%: risk factors included open versus laparoscopic reoperation (aOR = 4.38, p = 0.03) and ICU admission (aOR = 3.63, p = 0.05). Median (IQR) overall LOS was 20 days (14-26), higher in the subgroup of patients reoperated without stoma. At 1 year, a stoma persisted in 32.0% of patients, higher in the open (41.2%) versus laparoscopic (12.5%) reoperation group (p = 0.04). Only 4 out of 18 patients (22.2%) were able to RIOT., Conclusion: Mortality and/or unplanned ICU admission rates after AL are influenced by increasing age and by anastomotic breakdown at reoperation; additional morbidity rates are influenced by unplanned ICU admission and by laparoscopic approach to reoperation, the latter also reducing permanent stoma and failure to RIOT rates., Trial Registration: ClinicalTrials.gov # NCT03560180.
Published: 2021
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16. Early diagnosis of anastomotic leakage after colorectal surgery by the Dutch leakage score, serum procalcitonin and serum C-reactive protein: study protocol of a prospective multicentre observational study by the Italian ColoRectal Anastomotic Leakage (iC.

Author: Benedetti M, Ciano P, Pergolini I, Ciotti S, Guercioni G, Ruffo G, Borghi F, Patriti A, Del Rio P, Scatizzi M, Mancini S, Garulli G, Carrara A, Pirozzi F, Scabini S, Liverani A, Baiocchi G, Campagnacci R, Muratore A, Longo G, Caricato M, Macarone Palmieri R, Vettoretto N, Ceccaroni M, Guadagni S, Bertocchi E, Cianflocca D, Lambertini M, Pace U, Baraghini M, Pandolfini L, Angeloni R, Lucchi A, Martorelli G, Tirone G, Motter M, Sciuto A, Martino A, Luzzi AP, Di Cesare T, Molfino S, Maurizi A, Marsanic P, Tomassini F, Santoni S, Capolupo GT, Amodio P, Arici E, Clementi M, Ruggeri B, and Catarci M
Subjects: Anastomotic Leak blood, Biomarkers blood, Early Diagnosis, Elective Surgical Procedures adverse effects, Humans, Leukocyte Count, Outcome Assessment, Health Care, Prospective Studies, Risk Factors, Sample Size, Surgical Wound Dehiscence complications, Anastomotic Leak diagnosis, C-Reactive Protein analysis, Colon surgery, Procalcitonin blood, Rectum surgery
Abstract: Background: Anastomotic leakage (AL) is a dreaded major complication after colorectal surgery. There is no uniform definition of anastomotic dehiscence and leak. Over the years many risk factors have been identified (distance of anastomosis from anal verge, gender, BMI, ASA score) but none of these allows an early diagnosis of AL. The DUtch LeaKage (DULK) score, C reactive protein (CRP) and procalcitonin (PCT) have been identified as early predictors for anastomotic leakage starting from postoperative day (POD) 2-3. The study was designed to prospectively evaluate AL rates after colorectal resections, in order to give a definite answer to the need for clear risk factors, and testing the diagnostic yeld of DULK score and of laboratory markers. Methods and analysis. A prospective enrollment for all patients undergoing elective colorectal surgery with anastomosis carried out from September 2017 to September 2018 in 19 Italian surgical centers., Outcome Measures: preoperative risk factors of anastomotic leakage; operative parameters; leukocyte count, serum CRP, serum PCT and DULK score assessment on POD 2 and 3. Primary endpoint is AL; secondary endpoints are minor and major complications according to Clavien-Dindo classification; morbidity and mortality rates; readmission and reoperation rates, length of postoperative hospital stay (Retrospectively registered at ClinicalTrials.gov Identifier: NCT03560180, on June 18, 2018). Ethics. The ethics committee of the "Comitato Etico Regionale delle Marche - C.E.R.M." reviewed and approved this study protocol on September 7, 2017 (protocol no. 2017-0244-AS). All the participating centers submitted the protocol and obtained authorization from the local Institutional Review Board.
Published: 2019

17. Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program.

Author: Pirrera B, Alagna V, Lucchi A, Berti P, Gabbianelli C, Martorelli G, Mozzoni L, Ruggeri F, Ingardia A, Nardi G, and Garulli G
Subjects: Abdominal Muscles drug effects, Abdominal Muscles innervation, Abdominal Muscles surgery, Adult, Aged, Aged, 80 and over, Analgesia, Epidural adverse effects, Analgesics, Opioid, Anti-Inflammatory Agents, Non-Steroidal administration & dosage, Case-Control Studies, Colectomy methods, Colon surgery, Colonic Diseases surgery, Female, Humans, Laparoscopy methods, Length of Stay statistics & numerical data, Male, Middle Aged, Nerve Block adverse effects, Pain Measurement, Patient Readmission statistics & numerical data, Retrospective Studies, Survival Rate, Analgesia, Epidural methods, Colectomy adverse effects, Laparoscopy adverse effects, Nerve Block methods, Pain, Postoperative therapy
Abstract: Aim: The enhanced recovery after surgery (ERAS) pathway and laparoscopic approach had been proven beneficial for patients and should now be considered as a standard of care in colorectal surgery. Multimodal analgesia is the gold standard in the ERAS program with the use of thoracic epidural analgesia (TEA). Few data are available on Transversus abdominis plane (TAP) blocks in laparoscopic colorectal surgery and ERAS pathway. The aim of this study is to evaluate the efficacy of TAP block compared to TEA in the management of postoperative pain and the impact on the recurrence of postoperative nausea, vomiting and ileus in laparoscopic colorectal surgery in the ERAS program., Method: From October 2014 to October 2016, 182 patients underwent elective colon surgical interventions in enhanced recovery after surgery pathway. The patients were divided into two groups: Group 1 (n = 92) and Group 2 (n = 91) who received TEA and TAP block, respectively, with a standardized postoperative analgesic regimen consisting of regular 1 g of paracetamol every 8 h and a rescue dose with intravenous non-steroidal anti-inflammatory drugs infusion for both groups., Results: No differences were observed in baseline patient characteristics, clinical variables and surgical procedures between the two groups, as well as in the postoperative complications rate (p = 0.515) in accordance with Clavien-Dindo classification, 90-day mortality (p = 0.319), hospital stay (p = 0.469) and 30-day readmission rate (p = 0.711). Patients in the TAP block group showed lower postoperative nausea and vomiting rates (p = 0.025), as well as lower ileus (p = 0.031) and paraesthesia rates (p = 0.024). No differences were found in urinary retention (p = 0.157). Despite the "opioid-free" analgesia protocol in the TAP block group, pain intensity was comparable between the two groups (p = 0.651)., Conclusion: TAP block combined with an opioid-sparing analgesia in the setting of the laparoscopic colorectal surgery and ERAS program is feasible and effective in postoperative pain control.
Published: 2018
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18. E.R.A.S. pathway in colorectal surgery in elderly: Our experience: A retrospective cohort study.

Author: Pirrera B, Lucchi A, Gabbianelli C, Alagna V, Martorelli G, Berti P, Panzini I, Fabbri E, and Garulli G
Subjects: Age Factors, Aged, Aged, 80 and over, Elective Surgical Procedures adverse effects, Female, Humans, Length of Stay, Logistic Models, Male, Postoperative Complications prevention & control, Recovery of Function, Retrospective Studies, Colorectal Surgery mortality
Abstract: Aim: Numerous geriatric patients develop colorectal disease. Elderly patients are often considered high-risk surgical candidates. Enhanced recovery after surgery (E.R.A.S.) has been proven to be beneficial for patients. The aim of the study was to evaluate the results of an ERAS protocol in older patients that underwent colorectal surgery compared to younger patients., Method: In the period between January 2010 to December 2015 a total of 589 patients underwent elective colorectal surgical interventions treated within the E.R.A.S pathway: 211 patients younger than 65 years, 175 patients aged from 66 years to 75 years, and 203 patients older than 75 years. End point of interest were postoperative complications, 90-day mortality, length of hospital stay and readmission within 30 days., Results: Significant differences between the three groups were observed for comorbidities (p:0.001); in particular older patients had significantly more diabetes, renal, cardiac, and respiratory diseases, ASA (p < 0.001), presence of malignancy (p < 0.001). However there were not differences between the groups in surgical procedures (p = 0.095), operative time (p = 0.823), anastomotic leakage (p = 0.960), hospital stay (p = 0.081), readmission rate (p = 0.904), 90-days mortality (p = 0.183) and morbidity (p = 0.973) in accordance with Clavien-Dindo classification. Multivariate logistic regression analysis showed that advanced age in E.R.A.S. pathway is not a predictive factor of morbidity, readmission within 30 days and 90-day mortality., Conclusion: There was no significant difference in morbidity, 90-day mortality, length of stay or readmission rate in patients aged over 75 years compared with younger patients. Old age does not represent a contraindication to the implementation of the E.R.A.S protocol in patients that underwent colorectal surgery. WHAT DOES THIS PAPER ADD TO THE EXISTING LITERATURE?: In the literature there are not many studies that address the impact of older age in the treatment of colorectal disease in an ERAS program. The aging of the population raises new questions in the management of the colorectal surgery in the elderly. ERAS pathway has been proven to be beneficial for patients, which results in a reduction of postoperative morbidity. Compared to what is reported in the literature this study confirms that ERAS program in colorectal surgery can be applied in older patients with no significant difference in morbidity, 90-day mortality, length of stay or readmission rate compared with younger., (Copyright © 2017. Published by Elsevier Ltd.)
Published: 2017
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19. One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation.

Author: di Francesco F, Cautero N, Vincenzi P, Nicolini D, De Luca S, Vecchi A, Garelli P, Martorelli G, Gentili M, Risaliti A, and Boemi M
Subjects: Adult, Drug Administration Schedule, Drug Therapy, Combination, Everolimus, Female, Humans, Mycophenolic Acid administration & dosage, Mycophenolic Acid analogs & derivatives, Sirolimus administration & dosage, Tacrolimus administration & dosage, Time Factors, Treatment Outcome, Diabetes Mellitus, Type 1 surgery, Immunosuppressive Agents administration & dosage, Pancreas Transplantation, Sirolimus analogs & derivatives
Published: 2008
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19 results on '"Martorelli, G."'

1. Abdominal drainage after elective colorectal surgery: propensity score-matched retrospective analysis of an Italian cohort

2. Mechanical bowel preparation in elective colorectal surgery: a propensity score-matched analysis of the Italian colorectal anastomotic leakage (iCral) study group prospective cohorts

3. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

4. Three-row versus two-row circular staplers for left-sided colorectal anastomosis: a propensity score-matched analysis of the iCral 2 and 3 prospective cohorts

5. ERAS program adherence-institutionalization, major morbidity and anastomotic leakage after elective colorectal surgery: the iCral2 multicenter prospective study

6. Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

7. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

8. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

9. Technical Solutions for Venous Outflow Reconstruction in Damaged Liver Grafts During Procurement: Case Reports

10. Le variazioni della Merula torquata (Naum.)

11. Peritoneal Leiomyosarcoma in a Kidney Transplant Patient: A Case Report

12. F-29 Transarterial chemoembolization (TACE) with doxorubicin-eluting-bead versus conventional TACE in patients listed for liver transplantation: impact on tumor necrosis and post transplant disease-free survival

13. Early diagnosis of anastomotic leakage after colorectal surgery by the dutch leakage score, serum procalcitonin and serum c-reactive protein: Study protocol of a prospective multicentre observational study by the Italian ColoRectal anastomotic leakage (iCral) study group

14. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

15. Management and 1-year outcomes of anastomotic leakage after elective colorectal surgery.

16. Early diagnosis of anastomotic leakage after colorectal surgery by the Dutch leakage score, serum procalcitonin and serum C-reactive protein: study protocol of a prospective multicentre observational study by the Italian ColoRectal Anastomotic Leakage (iC.

17. Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program.

18. E.R.A.S. pathway in colorectal surgery in elderly: Our experience: A retrospective cohort study.

19. One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation.

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