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2. IRIDE White Book, An Interdisciplinary Research Infrastructure based on Dual Electron linacs&lasers

Author

Alesini, D., Alessandroni, M., Anania, M. P., Andreas, S., Angelone, M., Arcovito, A., Arnesano, F., Artioli, M., Avaldi, L., Babusci, D., Bacci, A., Balerna, A., Bartalucci, S., Bedogni, R., Bellaveglia, M., Bencivenga, F., Benfatto, M., Biedron, S., Bocci, V., Bolognesi, M., Bolognesi, P., Boni, R., Bonifacio, R., Boscolo, M., Boscherini, F., Bossi, F., Broggi, F., Buonomo, B., Calo', V., Catone, D., Capogni, M., Capone, M., Castellano, M., Castoldi, A., Catani, L., Cavoto, G., Cherubini, N., Chirico, G., Cestelli-Guidi, M., Chiadroni, E., Chiarella, V., Cianchi, A., Cianci, M., Cimino, R., Ciocci, F., Clozza, A., Collini, M., Colo', G., Compagno, A., Contini, G., Coreno, M., Cucini, R., Curceanu, C., Dabagov, S., Dainese, E., Davoli, I., Dattoli, G., De Caro, L., De Felice, P., Della Longa, S., Monache, G. Delle, De Spirito, M., Di Cicco, A., Di Donato, C., Di Gioacchino, D., Di Giovenale, D., Di Palma, E., Di Pirro, G., Dodaro, A., Doria, A., Dosselli, U., Drago, A., Escribano, R., Esposito, A., Faccini, R., Ferrari, A., Ferrario, M., Filabozzi, A., Filippetto, D., Fiori, F., Frasciello, O., Fulgentini, L., Gallerano, G. P., Gallo, A., Gambaccini, M., Gatti, C., Gatti, G., Gauzzi, P., Ghigo, A., Ghiringhelli, G., Giannessi, L., Giardina, G., Giannini, C., Giorgianni, F., Giovenale, E., Gizzi, L., Guaraldo, C., Guazzoni, C., Gunnella, R., Hatada, K., Ivashyn, S., Jegerlehner, F., Keeffe, P. O., Kluge, W., Kupsc, A., Iannone, M., Labate, L., Sandri, P. Levi, Lombardi, V., Londrillo, P., Loreti, S., Losacco, M., Lupi, S., Macchi, A., Magazu', S., Mandaglio, G., Marcelli, A., Margutti, G., Mariani, C., Mariani, P., Marzo, G., Masciovecchio, C., Masjuan, P., Mattioli, M., Mazzitelli, G., Merenkov, N. P., Michelato, P., Migliardo, F., Migliorati, M., Milardi, C., Milotti, E., Milton, S., Minicozzi, V., Mobilio, S., Morante, S., Moricciani, D., Mostacci, A., Muccifora, V., Murtas, F., Musumeci, P., Nguyen, F., Orecchini, A., Organtini, G., Ottaviani, P. L., Pace, E., Paci, M., Pagani, C., Pagnutti, S., Palmieri, V., Palumbo, L., Panaccione, G. C., Papadopoulos, C. F., Papi, M., Passera, M., Pasquini, L., Pedio, M., Perrone, A., Petralia, A., Petrillo, C., Petrillo, V., Pillon, M., Pierini, P., Pietropaolo, A., Polosa, A. D., Pompili, R., Portoles, J., Prosperi, T., Quaresima, C., Quintieri, L., Rau, J. V., Reconditi, M., Ricci, A., Ricci, R., Ricciardi, G., Ripiccini, E., Romeo, S., Ronsivalle, C., Rosato, N., Rosenzweig, J. B., Rossi, G., Rossi, A. A., Rossi, A. R., Rossi, F., Russo, D., Sabatucci, A., Sabia, E., Sacchetti, F., Salducco, S., Sannibale, F., Sarri, G., Scopigno, T., Serafini, L., Sertore, D., Shekhovtsova, O., Spassovsky, I., Spadaro, T., Spataro, B., Spinozzi, F., Stecchi, A., Stellato, F., Surrenti, V., Tenore, A., Torre, A., Trentadue, L., Turchini, S., Vaccarezza, C., Vacchi, A., Valente, P., Venanzoni, G., Vescovi, S., Villa, F., Zanotti, G., Zema, N., and Zobov, M.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Physics - Accelerator Physics
Abstract

This report describes the scientific aims and potentials as well as the preliminary technical design of IRIDE, an innovative tool for multi-disciplinary investigations in a wide field of scientific, technological and industrial applications. IRIDE will be a high intensity 'particle factory', based on a combination of a high duty cycle radio-frequency superconducting electron linac and of high energy lasers. Conceived to provide unique research possibilities for particle physics, for condensed matter physics, chemistry and material science, for structural biology and industrial applications, IRIDE will open completely new research possibilities and advance our knowledge in many branches of science and technology. IRIDE will contribute to open new avenues of discoveries and to address most important riddles: What does matter consist of? What is the structure of proteins that have a fundamental role in life processes? What can we learn from protein structure to improve the treatment of diseases and to design more efficient drugs? But also how does an electronic chip behave under the effect of radiations? How can the heat flow in a large heat exchanger be optimized? The scientific potential of IRIDE is far reaching and justifies the construction of such a large facility in Italy in synergy with the national research institutes and companies and in the framework of the European and international research. It will impact also on R&D work for ILC, FEL, and will be complementarity to other large scale accelerator projects. IRIDE is also intended to be realized in subsequent stages of development depending on the assigned priorities., Comment: 270 pages

Published
2013

4. Analysis of maxillary arch expansion in growing patients treated with early Class III protocol versus RME

Author

d'Apuzzo, F, Nucci, L, Correra, A, Minervini, G, Quinzi, V, Marzo, G, Franchi, L, Grassia, V, D'Apuzzo, F, Nucci, L, Correra, A, Minervini, G, Quinzi, V, Marzo, G, Franchi, L, and Grassia, V

Subjects
Hyrax expander, bonded expander, rapid maxillaryexpansion, modified SEC III protocol, Maxillary expansion
Abstract

Aim: To evaluate and compare the maxillary arch expansion obtained in growing patients treated with Class III early treatment protocol (the modified SEC III protocol), or rapid maxillary expansion (RME). Methods: This retrospective observational study included patients in the mixed dentition with maxillary constriction and/ or dental crowding. The first group consisted of 30 patients (11 males and 19 females, mean age 9.4 ±1.7 years) with dentoskeletal Class III malocclusion treated with the modified SEC III protocol. The second group of 30 patients (14 males and 16 females, mean age 9.3 ±1.5 years) with Class I or II malocclusion was treated with a Hyrax-type expander applied to bands on the first upper molars. For each subject, initial (T0) and post expansion (T1) digital dental casts were collected. The intermolar and intercanine widths, the arch lengths at both cusp and gingival levels, the anteroposterior length and the palatal depth were measured at T0 and T1. Results: At T1 there were statistically significant differences for 3-3 occlusal (OC) (P < 0.009), arch-length OC (P

Published
2023

10. Digital analysis of the occlusal changes and palatal morphology using elastodontic devices. A prospective clinical study including Class II subjects in mixed dentition

Author

Lo Giudice, A, Ronsivalle, V, Santonocito, S, Lucchese, A, Venezia, P, Marzo, G, Leonardi, R, and Quinzi, V

Subjects
3-d technology, Dental class ii malocclusion, Surface-to-surface superimposition, Digital workflow, Elastodontic appliances
Abstract

The aim of the present prospective study was to evaluate the effectiveness of elastodontic appliance (EAs) in the treatment of subjects presenting Class II sagittal discrepancy in mixed dentition, and to evaluate palatal morphological development during treatment.The study group, composed of 19 subjects, received treatment with EA for 1 year. The control group consisted of 17 untreated subjects.age between 6 and 11 years, mixed deciduous dentition and skeletal and/or dental Class II malocclusion.previous orthodontic therapy, systemic diseases and signs of temporal dysfunction. Skeletal and dentoalveolar parameters were compared between T0 and T1. A 3D imaging technology was used to compare palatal morphology obtained from intra-oral digital scans between T0 (pre-treatment) and T1 (post-treatment).EAs can successfully mitigate early signs of malocclusion in Class II subjects as well as contribute to the harmonious development of the palate.

Published
2022

34. Myofunctional therapy Part 2: Prevention of dentofacial disorders

Author

Gelb, M, Montrose, J, Paglia, L, Saccomanno, S, Quinzi, V, and Marzo, G

Subjects
Breathing, Occlusion, Prevention, Humans, Development, Sleep, Child, Airway Centric, Myofunctional Therapy
Abstract

AirwayCentric approach to prevention of dentofacial disorders. The correct development of functions is important for the prevention of dentofacial disorders from the first days of life. The first and foremost function, to which all others are adapting, is nasal breathing. The AirwayCentric® method focuses on nasal breathing during early development and throughout childhood to promote: Neurobehavioural development and the brain, development of the craniofacial and respiratory complex, correct dental occlusion, proper and restful sleep and to improve performance and life overall. By working at the same time on orofacial functions and structures, many dentofacial disorders can be prevented.

Published
2021

35. Myofunctional therapy. Part 1: Culture, industrialisation and the shrinking human face

Author

Boyd, K, Saccomanno, S, Lewis, C J, Coceani Paskay, L, Quinzi, V, and Marzo, G

Subjects
Prevention, Darwinian dentistry, Weaning, Diet, Orofacial myofunctional disorders, Craniofacial complex, Breathing, Child, Preschool, Humans, Child, Malocclusion, Early orthodontic treatment, Myofunctional Therapy
Abstract

Culture, industrialisation and the shrinking human face: Why is it important? Over the past 300,000 years, not only has the way we consume food from birth through our lifetime changed, there have also been changes related to the methods of food preparation, availability, processing, and storage. These diet-related factors, along with other epigenetic factors, have led to a widespread increase in orofacial myofunctional disorders (OMDs) and resultant human malocclusion phenotypes (HMPs) worldwide. Currently there is an increasing need for resolution of HMPs in early childhood and associated OMDs. This review will include reports of cases and describe the nature of the problem and strategies for effective solutions.

Published
2021

39. Oral and craniofacial manifestations of Ellis-Van Creveld syndrome: a systematic review

Author

Lauritano, D., Attuati, S., Besana, M., Rodilosso, G., Quinzi, V., Marzo, G., Carinci, F., Lauritano, D, Attuati, S, Besana, M, Rodilosso, G, Quinzi, V, Marzo, G, and Carinci, F

Subjects
Ellis-Van Creveld syndrome, chondroectodermal dysplasia, dental anomalies, malocclusion, rare diseases, Chondroectodermal dysplasia, Dental anomalies, Ellis-van creveld syndrome, Malocclusion, Rare diseases, Face, Humans, Ellis-Van Creveld Syndrome, NO, Human
Abstract

Aim A systematic literature review on oral and craniofacial manifestations of Ellis-Van Creveld syndrome was performed. Methods From 2 databases were selected 74 articles using as key words "Ellis-Van Creveld" AND "Oral" OR "Craniofacial" OR "Dental" OR "Malocclusion". Prisma protocol was used to create an eligible list for the screening. Data were collected in a table to compare the clinical aspects found. Results From the first research emerged 350 articles, and only 72 of them were selected. Conclusion Through this analysis oral and cranio-facial manifestations of Ellis-Van Creveld syndrome were pointed out. Management of Ellis-Van Creveld syndrome requires a multidisciplinary approach involving different clinicians; dentists play an important role in early diagnosis and treatment of the patients.

Published
2019

40. Paediatric orthodontics Part 4: SEC III protocol in class III malocclusion

Author

D'Apuzzo, F., Grassia, V., Quinzi, V., Vitale, M., Marzo, G., Perillo, L., D'Apuzzo, F., Grassia, V., Quinzi, V., Vitale, M., Marzo, G., and Perillo, L.

Subjects
Angle Class III, Cephalometry, Orthodontics, Interceptive, Orthodontics, Extraoral Traction Appliance, Mandible, Orthodontics, Corrective, Interceptive, Malocclusion, Angle Class III, Class III malocclusion, Early treatment, Corrective, Extraoral Traction Appliances, Humans, SEC III protocol, Child, Malocclusion, Human
Abstract

SEC III protocol: Early treatment of dentoskeletal Class III malocclusions. The early treatment of dentoskeletal Class III malocclusion is one of the more challenging situations for orthodontists, mainly for the uncertainty of stable long-term results due to the interaction of both environmental and genetic aetiological factors. Several interceptive protocols have been proposed during the past decades. The SEC III protocol includes two occlusal acrylic Splints combined with Class III elastics and chin cup. The protocol was proposed to facilitate Class III dentoskeletal correction by eliminating the intercuspation and the tongue thrust with clockwise mandibular rotation and minimal dentoalveolar compensation. The main difference with all the other appliances is the vertical control, which is crucial in difficult cases such as hyperdivergent Class III malocclusions.

Published
2019

42. Conclusioni

Author

Cordazzo, M. and Marzo, G.

Subjects
NO
Published
2020

43. The dentist's role in diagnosis and treatment of obstructive sleep apnea syndrome: a literature review

Author

Marchetti, E., Petro, E., Gaggioli, F., Lardani, L., Mancini, L., and Marzo, G.

Subjects
Sleep Apnea, Obstructive, Sleep Apnea, MAD, Obstructive, Dentists, OSAS, mandibular advancement devices, obstructive sleep apnea syndrome, snoring, Humans, Quality of Life, Cardiovascular Diseases, Hypertension, Mandibular advancement devices, Obstructive sleep apnea syndrome, Snoring
Abstract

The purpose of this work was to present a review of the literature concerning obstructive sleep apnea syndrome, and the role of the dentist in this pathology, both to identify elements useful for a good diagnosis and to apply the available therapeutic strategies. In literature there is no unanimous opinion on the treatment of OSAS. The multidisciplinary approach is necessary, creating teams made up of dentists, otolaryngologists and medical experts in sleep disorders, in order to develop a cooperation-based treatment plan for the disease. In this review, the importance of early diagnosis, orthodontic therapy in order to restore normal function is underlined, since OSAS is linked to a high risk of hypertension, cardiovascular diseases, daytime sleepiness, domestic and work accidents, with consequent deterioration of the quality of life.

Published
2020

47. Orthodontic treatment need and timing: Assessment of evolutive malocclusion conditions and associated risk factors

Author

Grippaudo, Cristina, Quinzi, V., Manai, Alice, Paolantonio, Ester Giulia, Valente, F., La Torre, G., Marzo, G., C. Grippaudo (ORCID:0000-0002-9499-0556), A. Manai, E. G. Paolantonio, Grippaudo, Cristina, Quinzi, V., Manai, Alice, Paolantonio, Ester Giulia, Valente, F., La Torre, G., Marzo, G., C. Grippaudo (ORCID:0000-0002-9499-0556), A. Manai, and E. G. Paolantonio

Abstract

Aim Orthodontic treatment need indexes are indispensable tools for collecting aepidemiological information, to define the need for clinical intervention on a graduated risk scale and to monitor the evolution of clinical conditions over time. The purpose of this research is to evaluate the prevalence of malocclusion and associated risk factors, and to compare the prevalence of malocclusion related to children’s growth. Investigating the correlation between malocclusion and dental occlusion development is crucial to define orthodontic timing and the most suitable treatment modalities. Materials and methods A cross-sectional, multi-center, observational study was carried out throughout Italy: 4,422 patients aged between 2 and 13 years were visited. The patients were divided into two age groups: one composed of patients aged 2 -7 years, and one of children between 8 and 13 years of age. The prevalence data were classified according to the items of the Baby ROMA (first group, deciduous/early mixed dentition) and ROMA Index (second group, late mixed/permanent dentition). Pearson’s Chi-square test was applied for the calculation of statistical significance in the comparison of prevalence data between the two age groups (P <0.05). Results The need for orthodontic treatment among Italian children is high. In the sample aged between 2 and 7 years, the most frequent malocclusions are the moderate and severe open bite (23%), moderate and severe Class II (21.2%), deep bite (18.8%), cross bite (16.5%), Class III (7.7%), and crowding (5.1%). In the sample aged between 8 and 13 years the most frequent malocclusions are crowding (50.8 %), Class II (33.1%), deep bite (19.2%) crossbite (18.1%), Class III (9.1%), open bite (6.6%), facial or mandibular asymmetries (3.3%), and functional asymmetries (3.2%). It was found a statistically significant variation of the different malocclusion conditions according to age. Conclusions The study confirms that some risk factors occur during gro

Published
2020

50. Pain and anxiety associated with Computer-Controlled Local Anaesthesia: Systematic review and meta-analysis of cross-over studies

Author

Libonati A., Nardi R., Gallusi G., Angotti V., Caruso S., Coniglione F., Marzo G., Mattei A., Tecco S., Paglia L., Campanella V., Libonati, A., Nardi, R., Gallusi, G., Angotti, V., Caruso, S., Coniglione, F., Marzo, G., Mattei, A., Tecco, S., Paglia, L., and Campanella, V.

Subjects
Injection, Cross-Over Studies, Anesthesia, Dental, CCLAD Dental anaesthesia, Pain, Cross-Over Studie, Perinatology and Child Health, Anxiety, Pediatrics, Settore MED/28, Injections, Therapy, Computer-Assisted, Dental Anxiety, Dentistry (all), Humans, Pain Management, Anesthetics, Local, Child, Pediatrics, Perinatology and Child Health, Dental Care for Children, Human, Pain Measurement
Abstract

This review focuses on Computer-Controlled Local Anaesthesia Delivery systems (CCLAD), in comparison with conventional carpule anaesthesia in means of pain and anxiety.Medline, Embase, Web of Science and Cochrane Database for Systematic Reviews were searched up to August 2018. Only cross-over split-mouth design studies aimed to clinically compare CCLAD with a conventional carpule anaesthesia are included. Data about pain and anxiety associated with anaesthesia were sought. The authors performed meta-analysis where appropriate.A total of 20 studies are included in the systematic review (n = 973 subjects). Quantitative synthesis (conducted on VAS scores from 8 studies) shows that pain intensity is over 9 points lower in CCLAD than in conventional anaesthesia on a scale from 0 to 100 (95% confidence interval, ?12.90 to ?5,53; P.001). The systematic review showed no differences between the two techniques according to the physiological parameters of pain (heart rate or blood pressure), and the data about anxiety are inconsistent.CCLAD results in significantly slightly less pain perception with respect to conventional injection and is a promising device to help patients. The literature needs to be expanded, mostly regarding anxiety.

Published
2018

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