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Hinoki cypress (Chamaecyparis obtusa) shows durability against termites and wood decay-causing fungi and is used as a construction material in Japan. However, the effects of the material are still not fully understood. The aim of this study was to evaluate whether Hinoki cypress has antimicrobial effects against airborne microorganisms. We examined the influence of Hinoki cypress on the growth of airborne bacteria and fungi using culture-based methods. The growth of bacterial colonies was observed after day 3 in the control group without Hinoki material. In contrast, the growth of bacterial colonies was observed after day 13 in the experimental group containing Hinoki material. In the experimental group, the number of fungal colonies was smaller than that in the control group, suggesting the antifungal effect of Hinoki cypress to some extent. In addition, we characterized the community structure of airborne bacteria in two rooms with and without cypress wood by the culture-independent method of PCR-denaturing gradient gel electrophoresis. This also suggested differences in the community structure of airborne bacteria depending on the presence or absence of Hinoki cypress wood. These results indicate that Hinoki cypress might be a useful functional material in building environments.

When antagonism is performed using sugammadex after continuous infusion of rocuronium, if the total amount of residual rocuronium can be esti- mated prior to performing antagonism, antagonism without excess or deficiency of sugammadex will be made possible. We therefore prepared a simple formula to predict residual amount of rocuronium in the body, which can be easily applied in clinical setting, and veri- fied it using Tivatrainer©.1. Pharmacokinetics of rocuronium was simulated, using a 3-compartment model. The following assumptions were made to derive the simple for- mula : when rocuronium is continuously infused to reach the steady state plasma concentration, an equal concentration in each compartment is reached. Only the amounts of rocuronium infused to the central com- partment and rocuronium excreted from there are thus considered, and these two amounts are in balance. For pharmacokinetic parameters, we referred to V. Saldien, Anesth Analg 2003 ; 97 : 44-9. 2. The prepared simple formula was verified using Tivatrainero. We considered a model in which initial boluses of 0.3, 0.6, 0.9, and 1.2 mg · kg(-1) were adminis- tered, and continuous infusion began at 30 minutes at the rate of 0.2, 0.3, 0.4, 0.5, 0.6, and 0.8 mg - kg-1 - hr-1. Patients with body weight of 50, 60, 70, and 80 kg were investigated.1. The derived simple formula was as fol- lows : Q=0.74 X R Q Total residual amount of rocuronium (mg) R Dose per hour (mg · hr(-1)) 2. The predicted value of the total residual amount obtained from the simple formula was consistent with the value predicted by Tivatrainer© with a high preci- sion within the error of 1.4%. Convergence time until the stable state was reached varied depending on the condition. However, it took approximately 150 minutes after the beginning of continuous infusion.for the error between values predicted by the simple formula and Tivatrainer© to stabilize within 5 mg.We prepared a simple formula to esti- mate the total residual amount of rocuronium at a steady state. The value predicted by the simple for- mula agreed with the value predicted by Tivatrainer) with a high precision.

The Japan Atomic Energy Agency (JAEA) has developed the prediction method for yield stress and ultimate tensile strength at liquid helium temperature (4 K) using the quadratic curve as a function of the content of carbon and nitrogen. Prediction method was formulated based on the tensile strength data of materials with shape of rectangle. In this study, tensile strength of the forged materials with round bar and complex shape were obtained so as to compare with the predicted value. The accuracy of the prediction method was 10.2% of Yield Strength (YS), 2.5% of Ultimate Tensile Strength (UTS) when the prediction method was applied to round bar forged materials. By contrast, the accuracy about prediction method was 1.8% of YS, -0.8% of UTS when prediction method was applied to complex shape forged materials. It can be presumed the tendency of tensile strength other than materials with shape of rectangle. However, it was found accuracy of round bar is larger than other materials because of difference in the forging method. “The views and opinions expressed herein do not necessarily reflect those of the ITER Organization”

This paper is proposing a new image investigating method. The word "image" is used in various meanings. It is the sensitivity-meaning referred to as dark or bright, and another means the digital picture which computer engineer is using. Semantic Differential method originated by C.E..Osgood is often used practically is the investigating method about a sensitivity image. The investigating method about a visual image has proposed here. The method is named Image Projective Method. This method expresses the brain picture that a man images to an object, on visual pictures concrete as a digital photograph. It expresses to a format as shown in Fig. 1. Structure analysis is performed for the picture taken up by the format. Covariance Structure Analysis and Factor Analysis are used as a technique. The analyzed example of the university introduction as an explannation example of this technique is given and explained.

A compact, semi-closed W-shaped divertor system has been designed, fabricated and installed in the JT-60U to replace the open divertor system. The new system consists of inclined divertors, a dome and baffles. To meet the structural requirements, a segmented structure with an electrically insulated flexible gas seal was applied. Using FEM codes, the system’s structural integrity was confirmed for the plasma disruptions by electromagnetic and structural analyses, which take into account the effect of halo currents. Substantial reduction of induced electromagnetic forces is attained in the divertor system due to the electrical insulation used for the gas seal structure. In addition, because of its segmented structure, the induced electromagnetic forces on each component unit are found to be limited. The maximum stress intensities and their ranges are obtained within allowable values. Thermal stress arising from the temperature difference between the divertor system and the vacuum vessel during the baking operation is also satisfactory. Furthermore, thermal and thermal stress analyses showed that the plasma facing components have sufficient structural integrity.

The purpose of this research is to clarify the future image of the network society which the young men imagine and to apply Quantification Analysis type 3, Fuzzy Quantification Analysis type 3 to obtained data. In these analysis, the model which took into consideration the membership value of a Fuzzy set F to the sample is assumed. Such high membership value is given that a knowledge level of the object is high. An investigation result is as an attached table 1. There, it has put together to 38 items by summarizing items which are similar each other. Moreover, five axes were obtained by the Quantification Analysis. They are the factors on Social-Individual Characteristic, Inside Nature-External-Surface Nature of Network Troubles, Informational Truth Nature, Decision Making, and Spread Problems. Also, Fuzzy Quantification Analysis type 3 is also helpful as for a few to extract above factors.

The cell cycle dependency of rice alpha-amylase production in Saccharomyces cerevisiae was investigated using synchronous and arrested cultures. The results of two separate synchronous cultures, using alpha-mating factor and a cdc28 mutant, indicated that the rice alpha-amylase-specific production rate is not constant during the cell cycle. The specific production rates during G1, S, and M phases were then ascertained by inhibiting the progression of the cell cycle using alpha-mating factor, hydroxyurea, and nocodazole, respectively. The specific production rate was found to be maximal during the M phase. The increase in the specific production rate during the M phase was confirmed from the accumulation of M-phase cells using a cdc15 mutant. The intracellular content of rice alpha-amylase was also measured during the cell cycle. Like the specific production rate, the intracellular content was found to fluctuate throughout the cell cycle, and to reach a maximum during M phase.

A typical example of rational system synthesis for bioproduction by the cultivation of microorganisms harboring a recombinant plasmid was studied. First, two temperature-controllable expression systems for a foreign gene in Saccharomyces cerevisiae were constructed. The promoter of the PHO84 gene, which encodes an inorganic phosphate (Pi) transporter of S. cerevisiae and is controlled by Pi concentration through the PHO regulatory system, was used. And two temperature-sensitive mutants of S. cerevisiae for the PHO regulatory system were used as the host with rice alpha-amylase expression vector. One was temperature-sensitive pho81 mutant, SH3337, and the other was temperature-sensitive pho80 mutant, YKU107. When the strain SH3337 is cultivated at a lower temperature, the rice alpha-amylase gene connected downstream of the PHO84 promoter is expressed, but at a higher temperature, it is not. Conversely, with the strain YKU107, the transcription of the rice alpha-amylase gene is induced at a higher temperature and repressed at a lower one. The optimal cultivation temperature strategies for maximum production of rice alpha-amylase in batch cultures of these two recombinant strains were then determined by the Maximum Principle using the relationships of the specific growth and specific production rates to the cultivation temperature. The optimal strategies were easy to realize and were shown to be effective for maximum product. Finally, under these maximum alpha-amylase production strategies, the alpha-amylase activities and alpha-amylase yields in terms of glucose consumption for these recombinant strains were calculated on the basis of experimental data and compared for various operation times. The study demonstrates how a foreign gene expression system can be synthesized using a temperature-sensitive mutant with a given objective and under given constraints.