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258 results on '"Massa, Elena"'

1. Atezolizumab and chemotherapy for advanced or recurrent endometrial cancer (AtTEnd): a randomised, double-blind, placebo-controlled, phase 3 trial

Author

Zola, Paolo, Casanova, Claudia, Arcangeli, Valentina, Antonuzzo, Lorenzo, Gadducci, Angiolo, Cosio, Stefania, Clamp, Andrew, Persic, Mojca, McNeish, Ian, Tookman, Laura, Redondo Sanchez, Andrés, Choi, Chel Hun, Baldini, Editta, Palaia, Innocenza, Benedetti Panici, Pierluigi, Takahashi, Nobutaka, Lombard, Janine, Ardizzoia, Antonio, Bologna, Alessandra, Herrero Ibáñez, Ana Maria, Musolino, Antonino, Márquez Vázquez, Raúl, Pietzner, Klaus, Braicu, Elena, Heinzelmann-Schwarz, Viola A., Powell, Melanie, Yokoyama, Yoshihito, Baron-Hay, Sally, Abeni, Chiara, Martin Lorente, Cristina, Cueva, Juan Fernando, Trillsch, Fabian, Heitz, Florian, Ataseven, Beyhan, Petru, Edgar, Heubner, MartinLeonhard, Sadozye, Azmat Hassanq, Dubey, Sidharth, Tazbirkova, Andrea, Tiley, Susan, Chrystal, Kathryn, Kim, Sang Wun, Fehr, Mathias, Scatchard, Kate, Anand, Anjana, Taylor, Alexandra, Watary, Hidemichi, Enomoto, Takayuki, Yoshihara, Kosuke, Selva-Nayagam, Sudarsha, Karki, Bhaskar, Harrison, Michelle, Wilkinson, Kate, Goh, Jeffrey, Glasgow, Amanda, Chantrill, Lorraine, Lee, Chulmin, Bertolini, Alessandro, Narducci, Filomena, Bellotti, Giovanna, Fusco, Vittorio, Aebi, Stefan, Del Grande, Maria, Colombo, Ilaria, Tokunaga, Hideki, Shigeta, Shogo, Goss, Geraldine, Siow, Zhen Rong, Steer, Christopher, Lin, Hao, Lee, Kwang-Beom, Di Meglio, Giovanni, Massa, Elena, De Marino, Elvira, Tortora, Vincenzo, Palacio Vazquez, Isabel, Tsuji, Kosuke, Tominaga, Eiichiro, Black, Allison, So, Kyeong A, Suh, Dong Hoon, Lee, Keun Ho, Kim, Yong Man, Fossati, Roldano, Carlucci, Luciano, Barberis, Massimo, Torri, Valter, Santoni, Anna, Colombo, Nicoletta, Biagioli, Elena, Harano, Kenichi, Galli, Francesca, Hudson, Emma, Antill, Yoland, Rabaglio, Manuela, Marmé, Frederic, Marth, Christian, Parma, Gabriella, Fariñas-Madrid, Lorena, Nishio, Shin, Allan, Karen, Lee, Yeh Chen, Piovano, Elisa, Pardo, Beatriz, Nakagawa, Satoshi, McQueen, John, Zamagni, Claudio, Manso, Luis, Takehara, Kazuhiro, Tasca, Giulia, Ferrero, Annamaria, Tognon, Germana, Lissoni, Andrea Alberto, Petrella, Mariacristina, Laudani, Maria Elena, Rulli, Eliana, Uggeri, Sara, and Barretina Ginesta, M Pilar

Published
2024
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2. Prediction of Response to Anti-Angiogenic Treatment for Advanced Colorectal Cancer Patients: From Biological Factors to Functional Imaging

Author

Corrias, Giuseppe, primary, Lai, Eleonora, additional, Ziranu, Pina, additional, Mariani, Stefano, additional, Donisi, Clelia, additional, Liscia, Nicole, additional, Saba, Giorgio, additional, Pretta, Andrea, additional, Persano, Mara, additional, Fanni, Daniela, additional, Spanu, Dario, additional, Balconi, Francesca, additional, Loi, Francesco, additional, Deidda, Simona, additional, Restivo, Angelo, additional, Pusceddu, Valeria, additional, Puzzoni, Marco, additional, Solinas, Cinzia, additional, Massa, Elena, additional, Madeddu, Clelia, additional, Gerosa, Clara, additional, Zorcolo, Luigi, additional, Faa, Gavino, additional, Saba, Luca, additional, and Scartozzi, Mario, additional

Published
2024
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3. Innate lymphoid cell recovery and occurrence of GvHD after hematopoietic stem cell transplantation

Author

Piperoglou, Christelle, Gomez Massa, Elena, Cruz Adalia, Aranzazu, Vély, Frédéric, Piperoglou, Christelle, Gomez Massa, Elena, Cruz Adalia, Aranzazu, and Vély, Frédéric

Abstract

Lymphocytes are essential for microbial immunity, tumor surveillance, and tissue homeostasis. However, the in vivo development and function of helper-like innate lymphoid cells (ILCs) in humans remain much less well understood than those of T, B, and NK cells. We monitored hematopoietic stem cell transplantation (HSCT) to determine the kinetics of ILC development in both children and adults. It was found that, unlike NK cells, helper-like ILCs recovered slowly, mirroring the pattern observed for T cells, with normalization achieved at 1 year. The type of graft and the proportion of CD34+ cells in the graft did not significantly affect ILC reconstitution. As HSCT is often complicated by acute or chronic graft-versus-host disease (GVHD), the potential role of ILC subsets in maintaining tissue integrity in these conditions was also analyzed. It was found that GVHD was associated with lower levels of activated and gut-homing NKp44+ ILCP, consistent with a non-redundant role of this ILC subset in preventing this life-threatening disorder in lymphopenic conditions., Depto. de Inmunología, Oftalmología y ORL, Fac. de Medicina, TRUE, pub

Published
2024

5. Active elderly and health—can moderate exercise improve health and wellbeing in older adults? Protocol for a randomized controlled trial

Author

Carta, Mauro Giovanni, Cossu, Giulia, Pintus, Elisa, Zoccheddu, Rosanna, Callia, Omar, Conti, Giuliana, Pintus, Mirra, Gonzalez, Cesar Ivan Aviles, Massidda, Maria Valeria, Mura, Gioia, Sardu, Claudia, Contu, Paolo, Minerba, Luigi, Demontis, Roberto, Pau, Massimiliano, Finco, Gabriele, Cocco, Eleonora, Penna, Maria Petronilla, Orrù, Germano, Kalcev, Goce, Cabras, Federico, Lorrai, Stefano, Loviselli, Andrea, Velluzzi, Fernanda, Monticone, Marco, Cacace, Enrico, Musu, Mario, Rongioletti, Franco, Cauli, Alberto, Ruggiero, Valeria, Scano, Alessandra, Crisafulli, Antonio, Cosentino, Sofia, Atzori, Laura, Massa, Elena, Mela, Quirico, Fortin, Dario, Migliaccio, Gianmario, Nardi, Antonio Egidio, Angermeyer, Matthias, and Preti, Antonio

Published
2021
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7. Immunotherapy and Cancer: The Multi-Omics Perspective.

Author

Donisi, Clelia, Pretta, Andrea, Pusceddu, Valeria, Ziranu, Pina, Lai, Eleonora, Puzzoni, Marco, Mariani, Stefano, Massa, Elena, Madeddu, Clelia, and Scartozzi, Mario

Subjects
MULTIOMICS, IMMUNOTHERAPY, CANCER treatment, TUMOR microenvironment, IMMUNE response
Abstract

Immunotherapies have revolutionized cancer treatment approaches. Because not all patients respond positively to immune therapeutic agents, it represents a challenge for scientists who strive to understand the mechanisms behind such resistance. In-depth exploration of tumor biology, using novel technologies such as omics science, can help decode the role of the tumor immune microenvironment (TIME) in producing a response to the immune blockade strategies. It can also help to identify biomarkers for patient stratification and personalized treatment. This review aims to explore these new models and highlight their possible pivotal role in changing clinical practice. [ABSTRACT FROM AUTHOR]

Published
2024
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13. 2022-RA-1526-ESGO Risk factors for sentinel lymph node involvement in patients with apparent early-stage endometrial cancer: a retrospective single-center study

Author

Deo, Giuseppe, primary, Fais, Maria Luisa, additional, Altieri, Alfonso, additional, Carboni, Giulia, additional, Fais, Giuseppina, additional, Ungredda, Andrea, additional, Fanni, Daniela, additional, Massa, Elena, additional, Mais, Valerio, additional, Angioni, Stefano, additional, and Peiretti, Michele, additional

Published
2022
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17. A Phase II Study with Antioxidants, both in the Diet and Supplemented, Pharmaco-Nutritional Support, Progestagen and Anti-COX-2 Showing Efficacy and Safety in Patients with Cancer-Related Anorexia-Cachexia and Oxidative Stress

Author

Mantovani, Giovanni, Madeddu, Clelia, Macciò, Antonio, Gramignano, Giulia, Lusso, Maria Rita, Massa, Elena, Astara, Giorgio, Serpe, Roberto, Mantovani, Giovanni, editor, Anker, Stefan D., editor, Inui, Akio, editor, Morley, John E., editor, Fanelli, Filippo Rossi, editor, Scevola, Daniele, editor, Schuster, Michael W., editor, and Yeh, Shing-Shing, editor

Published
2006
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18. Position paper of the Italian Association of Medical Oncology on early palliative care in oncology practice (Simultaneous Care)

Author

Zagonel, Vittorina, Franciosi, Vittorio, Brunello, Antonella, Biasco, Guido, Broglia, Chiara, Cattaneo, Daniela, Cavanna, Luigi, Corsi, Domenico, Farina, Gabriella, Fioretto, Luisa, Gamucci, Teresa, Lanzetta, Gaetano, Magarotto, Roberto, Maltoni, Marco, Marchetti, Paolo, Massa, Elena, Mastromauro, Cataldo, Melotti, Barbara, Meriggi, Fausto, Nacci, Angelo, Pavese, Ida, Piva, Erico, Quirino, Michela, Roselli, Mario, Sacco, Cosimo, Tonini, Giuseppe, Trentin, Leonardo, Ucci, Giovanni, Labianca, Roberto, Gori, Stefania, Pinto, Carmine, and Cascinu, Stefano

Published
2017
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21. The Quality of Life of People with Solid Cancer is Less Worse than Other Diseases with better Prognosis, Except in the Presence of Depression

Author

Aviles Gonzalez, Cesar Ivan, primary, Angermeyer, Matthias, additional, Deiana, Laura, additional, Loi, Caterina, additional, Murgia, Elisabetta, additional, Holzinger, Anita, additional, Cossu, Giulia, additional, Massa, Elena, additional, Romano, Ferdinando, additional, Scartozzi, Mario, additional, and Carta, Mauro Giovanni, additional

Published
2021
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24. Moderate Exercise Improves Cognitive Function in Healthy Elderly People: Results of a Randomized Controlled Trial

Author

Carta, Mauro Giovanni, primary, Cossu, Giulia, additional, Pintus, Elisa, additional, Zaccheddu, Rosanna, additional, Callia, Omar, additional, Conti, Giuliana, additional, Pintus, Mirra, additional, Aviles Gonzalez, Cesar Ivan, additional, Massidda, Maria Valeria, additional, Mura, Gioia, additional, Sardu, Claudia, additional, Contu, Paolo, additional, Minerba, Luigi, additional, Demontis, Roberto, additional, Pau, Massimiliano, additional, Finco, Gabriele, additional, Cocco, Eleonora, additional, Penna, Maria Pietronilla, additional, Orr, Germano, additional, Kalcev, Goce, additional, Cabras, Federico, additional, Lorrai, Stefano, additional, Loviselli, Andrea, additional, Velluzzi, Fernanda, additional, Monticone, Marco, additional, Cacace, Enrico, additional, Musu, Mario, additional, Rongioletti, Franco, additional, Cauli, Alberto, additional, Ruggiero, Valeria, additional, Scano, Alessandra, additional, Crisafulli, Antonio, additional, Cosentino, Sofia, additional, Atzori, Laura, additional, Massa, Elena, additional, Mela, Quirico, additional, Fortin, Dario, additional, Migliaccio, Gianmario, additional, Machado, Sergio, additional, Romano, Ferdinando, additional, and Preti, Antonio, additional

Published
2021
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25. Alcohol Consumption Is a Modifiable Risk Factor for Breast Cancer: Are Women Aware of This Relationship?

Author

Agabio, Roberta, Madeddu, Clelia, Contu, Paolo, Cosentino, Sofia, Deiana, Monica, Massa, Elena, Mereu, Alessandra, Politi, Carola, Sardu, Claudia, and Sinclair, Julia M A

Subjects
BREAST tumor risk factors, HEALTH literacy, ALCOHOL drinking, QUESTIONNAIRES, DESCRIPTIVE statistics, WOMEN'S health, HEALTH promotion
Abstract

Aims Despite alcohol consumption being a dose-dependent risk factor for breast cancer, a recent study conducted in the UK found <20% of women attending breast screening programmes were aware of this relationship and proposed proper information campaigns need to be conducted. We aimed to investigate the awareness of this relationship among a related sample of Italian women to evaluate whether similar information campaigns should also be conducted in Italy. Methods The questionnaire used by the UK study was translated into Italian, slightly modified for the Italian context, validated and submitted to a sample of Italian women. Results Overall 507 women were interviewed. Among them, 160 were classified as breast cancer screening attenders (SG), 44 as symptomatic breast clinic attenders (CAG) and 303 as non-screening group (NSG). Alcohol was correctly identified as a risk factor for breast cancer by 16.9, 11.4 and 14.9% of participants of SG, CAG and NSG, respectively without differences between the three groups. Despite the methodological differences, the rates of participants who correctly identified alcohol as a risk factor among women attending breast screening programmes were surprisingly similar between the study conducted in UK (15.7%) and the present study (16.9%). Conclusion The results of the present study confirm the limited awareness of the relationship between alcohol consumption and risk of developing breast cancer among women and suggest the urgent need to conduct proper awareness-raising campaigns to counter this in the Italian female population. [ABSTRACT FROM AUTHOR]

Published
2022
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28. Additional file 1 of Active elderly and health—can moderate exercise improve health and wellbeing in older adults? Protocol for a randomized controlled trial

Author

Carta, Mauro Giovanni, Cossu, Giulia, Pintus, Elisa, Zoccheddu, Rosanna, Callia, Omar, Conti, Giuliana, Mirra Pintus, Gonzalez, Cesar Ivan Aviles, Massidda, Maria Valeria, Mura, Gioia, Sardu, Claudia, Contu, Paolo, Minerba, Luigi, Demontis, Roberto, Pau, Massimiliano, Finco, Gabriele, Cocco, Eleonora, Penna, Maria Petronilla, Orrù, Germano, Kalcev, Goce, Cabras, Federico, Lorrai, Stefano, Loviselli, Andrea, Velluzzi, Fernanda, Monticone, Marco, Cacace, Enrico, Musu, Mario, Rongioletti, Franco, Cauli, Alberto, Ruggiero, Valeria, Scano, Alessandra, Crisafulli, Antonio, Cosentino, Sofia, Atzori, Laura, Massa, Elena, Mela, Quirico, Fortin, Dario, Migliaccio, Gianmario, Nardi, Antonio Egidio, Angermeyer, Matthias, and Preti, Antonio

Abstract

Additional file 1. See the SPIRIT 2013 checklist.

Published
2021
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33. Letter to the Editor.

Author

Fanni, Daniela, Gerosa, Clara, Peiretti, Michele, Mais, Valerio, Massa, Elena, Angioni, Stefano, and Faa, Gavino

Published
2024
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35. The association between Major Depressive Disorder and premature death risk in hematologic and solid cancer: a longitudinal cohort study

Author

Sancassiani, Federica, primary, Massa, Elena, additional, Pibia, Carla, additional, Perda, Giulia, additional, Boe, Laura, additional, Fantozzi, Elena, additional, Cossu, Giulia, additional, Caocci, Giovanni, additional, Mulas, Olga, additional, Morelli, Emanuela, additional, Lindert, Jutta, additional, Lai, Eleonora, additional, Nardi, Antonio Egidio, additional, Scartozzi, Mario, additional, La Nasa, Giorgio, additional, and Carta, Mauro Giovanni, additional

Published
2021
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37. Células linfoides innatas en el contexto de la alorrespuesta inmune en trasplante de órgano sólido

Author

Gómez Massa, Elena, Paz Artal, Estela, and Talayero Giménez de Azcarate, Paloma

Subjects
Cirugía
Abstract

El trasplante de órgano sólido (TOS) es el mejor tratamiento para los pacientes con disfunción terminal de un órgano. Los protocolos actuales de inmunosupresión están focalizados en el control de los linfocitos T (LT) para evitar el rechazo celular y de los linfocitos B (LB) para evitar el rechazo humoral. Sin embargo, la supervivencia del injerto a largo plazo sigue estando limitada por la respuesta inmunológica que puede promover un estado pro-inflamatorio (rechazo), antiinflamatorio(homeostasis-tolerancia) o fibrosis (deterioro del injerto). Por lo tanto, otros compartimentos distintos de la respuesta inmune adaptativa podrían estar contribuyendo en la alorrespuesta del injerto...

Published
2020

39. Células linfoides innatas en el contexto de la alorrespuesta inmune en trasplante de órgano sólido

Author

Paz Artal, Estela, Talayero Giménez de Azcarate, Paloma, Gómez Massa, Elena, Paz Artal, Estela, Talayero Giménez de Azcarate, Paloma, and Gómez Massa, Elena

Abstract

El trasplante de órgano sólido (TOS) es el mejor tratamiento para los pacientes con disfunción terminal de un órgano. Los protocolos actuales de inmunosupresión están focalizados en el control de los linfocitos T (LT) para evitar el rechazo celular y de los linfocitos B (LB) para evitar el rechazo humoral. Sin embargo, la supervivencia del injerto a largo plazo sigue estando limitada por la respuesta inmunológica que puede promover un estado pro-inflamatorio (rechazo), antiinflamatorio(homeostasis-tolerancia) o fibrosis (deterioro del injerto). Por lo tanto, otros compartimentos distintos de la respuesta inmune adaptativa podrían estar contribuyendo en la alorrespuesta del injerto..., Solid organ transplantation (SOT) represents the preferred treatment option for patients with terminal organ failure. Current immunosuppressive protocols are mostly focused to constrain the T cell response to avoid cellular rejection and B cell response to avoid humoral rejection. However, long-term graft survival is still limited by the immune response that is able to promote a pro-inflammatory state (rejection), an anti-inflammatory state (tolerance) or fibrosis (graft deterioration). Thus, other immune response compartments apart from the adaptive counterpart may contribute to alloresponse...

Published
2020

46. Molecular-Biology-Driven Treatment for Metastatic Colorectal Cancer

Author

Lai, Eleonora, primary, Liscia, Nicole, additional, Donisi, Clelia, additional, Mariani, Stefano, additional, Tolu, Simona, additional, Pretta, Andrea, additional, Persano, Mara, additional, Pinna, Giovanna, additional, Balconi, Francesca, additional, Pireddu, Annagrazia, additional, Impera, Valentino, additional, Dubois, Marco, additional, Migliari, Marco, additional, Spanu, Dario, additional, Saba, Giorgio, additional, Camera, Silvia, additional, Musio, Francesca, additional, Ziranu, Pina, additional, Puzzoni, Marco, additional, Demurtas, Laura, additional, Pusceddu, Valeria, additional, Dettori, Manuela, additional, Massa, Elena, additional, Atzori, Francesco, additional, Dessì, Mariele, additional, Astara, Giorgio, additional, Madeddu, Clelia, additional, and Scartozzi, Mario, additional

Published
2020
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47. Donor helper innate lymphoid cells are replaced earlier than lineage positive cells and persist long‐term in human intestinal grafts – a descriptive study

Author

Gómez‐Massa, Elena, primary, Lasa‐Lázaro, María, additional, Gil‐Etayo, Francisco Javier, additional, Ulloa‐Márquez, Esperanza, additional, Justo, Iago, additional, Loinaz, Carmelo, additional, Calvo‐Pulido, Jorge, additional, Paz‐Artal, Estela, additional, and Talayero, Paloma, additional

Published
2020
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48. Number and function of circulatory helper innate lymphoid cells are unaffected by immunosuppressive drugs used in solid organ recipients – a single centre cohort study

Author

Gómez‐Massa, Elena, primary, Talayero, Paloma, additional, Utrero‐Rico, Alberto, additional, Laguna‐Goya, Rocío, additional, Andrés, Amado, additional, Mancebo, Esther, additional, Leivas, Alejandra, additional, Polanco‐Fernández, Natalia, additional, Justo, Iago, additional, Jimenez‐Romero, Carlos, additional, Pleguezuelo, Daniel, additional, and Paz‐Artal, Estela, additional

Published
2020
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49. Neo-adjuvant chemo-(immuno-)therapy of advanced squamous-cell head and neck carcinoma: a multicenter, phase III, randomized study comparing cisplatin + 5-fluorouracil (5-FU) with cisplatin + 5-FU + recombinant interleukin 2

Author

Mantovani, Giovanni, Gebbia, Vittorio, Airoldi, Mario, Bumma, Cesare, Contu, Paolo, Bianchi, Alessandro, Ghiani, Massimo, Dessì, Daniela, Massa, Elena, Curreli, Luigi, Lampis, Biancarosa, Lai, Paola, Mulas, Carlo, Testa, Antonio, Proto, Ernesto, Cadeddu, Gabrio, and Tore, Giorgio

Published
1998
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50. Innate lymphoid cell recovery and occurrence of GvHD after hematopoietic stem cell transplantation.

Author

Piperoglou, Christelle, Larid, Guillaume, Vallentin, Blandine, Balligand, Laura, Crinier, Adeline, Banzet, Nathalie, Farnarier, Catherine, Gomez‐Massa, Elena, Adalia, Aranzazu Cruz, Michel, Gérard, Galambrun, Claire, Barlogis, Vincent, Vivier, Eric, and Vély, Frédéric

Subjects
HEMATOPOIETIC stem cell transplantation, INNATE lymphoid cells, KILLER cells, T cells, ACUTE diseases, GRAFT versus host disease
Abstract

Lymphocytes are essential for microbial immunity, tumor surveillance, and tissue homeostasis. However, the in vivo development and function of helper‐like innate lymphoid cells (ILCs) in humans remain much less well understood than those of T, B, and NK cells. We monitored hematopoietic stem cell transplantation (HSCT) to determine the kinetics of ILC development in both children and adults. It was found that, unlike NK cells, helper‐like ILCs recovered slowly, mirroring the pattern observed for T cells, with normalization achieved at 1 year. The type of graft and the proportion of CD34+ cells in the graft did not significantly affect ILC reconstitution. As HSCT is often complicated by acute or chronic graft‐versus‐host disease (GVHD), the potential role of ILC subsets in maintaining tissue integrity in these conditions was also analyzed. It was found that GVHD was associated with lower levels of activated and gut‐homing NKp44+ ILCP, consistent with a non‐redundant role of this ILC subset in preventing this life‐threatening disorder in lymphopenic conditions. [ABSTRACT FROM AUTHOR]

Published
2022
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