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The purpose of this study was to evaluate changes in pain intensity among Veterans transitioning from long-term opioid therapy (LTOT) to either intermittent therapy or discontinuation compared to continued LTOT. Pain intensity was assessed using the Numeric Rating Scale in 90-day increments starting in the 90-day period prior to potential opioid transitions and the two ensuing 90-day periods after transition. Primary analyses used a 1:1 greedy propensity matched sample. A total of 29,293 Veterans switching to intermittent opioids and 5,972 discontinuing opioids were matched to Veterans continuing LTOT. Covariates were well balanced after matching except minor differences in baseline mean pain scores. Pain scores were lower in the follow up periods for those switching to intermittent opioids and discontinuing opioids compared to those continuing LTOT (0-90 days: Intermittent: 3.79, 95%CI: 3.76, 3.82; LTOT: 4.09, 95%CI: 4.06, 4.12, P < .0001; Discontinuation: 3.06, 95%CI: 2.99, 3.13; LTOT: 3.86, 95%CI: 3.79, 3.94, P =

We use a large administrative tax-returns panel dataset merged with a tax audit database to estimate the effect of real-world operational tax audits on subsequent tax behavior of a large sample of Italian self-employed taxpayers. Results from operational audits do not suffer from the fact that taxpayers are aware that they have been randomly selected for research purposes and, then, such audits are viewed as more of a signal about true audit rates by the taxpayer. Our empirical approach relies on fixed-effects difference-in-difference comparisons with an ex-ante matched sample of non-audited taxpayers. To address concerns about the endogenous selection into audit, we provide evidence for the common trends assumption. We find a positive and lasting effect of audits on subsequent reported income. However, in line with theoretical predictions, taxpayers do not increase tax compliance when the tax authority does not assess a positive additional income. Our results are robust to a variety of specifications and samples.

Objective To assess the rate of immediate postpartum long-acting reversible contraceptive (LARC) use in a multihospital health care system 2 years before and after the policy was implemented, and to assess factors associated with LARC use and repeat pregnancy rates within 12 months after delivery. Methods We conducted a retrospective chart review of all patients giving birth at three Cleveland Clinic Ohio hospitals from July 1, 2015, to June 30, 2019. We reviewed the inpatient medication reconciliation to identify the LARC initiation rate. We compared all patients who received inpatient postpartum LARC to a 1:3 matched sample of patients who did not receive LARC, matched by delivery date and location, to identify patient characteristics associated with LARC use. The electronic medical record (Epic) was reviewed to identify new pregnancies occurring within 12 months postdelivery. Results We identified 17,848 deliveries prepolicy and 18,555 deliveries postpolicy. Immediate postpartum LARC was used by 0.5% (monthly range 0-2.1%) of patients prepolicy and 11.6% (monthly range 8.3-15.4%) of patients postpolicy. Levonorgestrel intrauterine devices (IUDs) were used by 56.5%, implants by 29.1%, and copper IUDs by 14.5% of LARC users. Characteristics associated with LARC use included younger age, public insurance, non-White race, Hispanic or Latina ethnicity, higher body mass index, sexually transmitted infection in pregnancy, and tobacco use. Long-acting reversible contraceptive users had a lower rate of repeat pregnancy at 12 months postpartum compared with the non-LARC group (1.9% vs 3.6%, P Conclusion Immediate postpartum LARC use increased after a state policy change mandated universal access and was associated with decreased pregnancy rates in the first year postdelivery.

Newsmedia have regularly reported about acts of terrorism that involved members of the same family, but also about instances where one sibling becomes a terrorist, whereas the other becomes a successful, law-abiding citizen. The question is, then, to what extent family circumstances and individual risk factors impact on pathways towards these shared or divergent outcomes. To date, studies on the family characteristics of terrorist suspects have been hampered by a lack of empirical data, small sample sizes and non-representative samples. Using register data on individuals suspected of a terrorist offense in the Netherlands and their family members, the present study examines the demographic and socio-economic characteristics of the families, as well as criminal, employment and education careers of individual family members (parents and brothers/sisters). We compare these characteristics with those of two control groups: suspects of non-terrorist offenses and a matched sample from the population. We also compared the terrorist suspects with matched siblings who were not suspected of a terrorist offence. We will end with a discussion of both risk and protective factors that are present within these families and that can put members of the same family on different pathways.

Protean career orientation (PCO) has been regarded as an emergent career attitude that challenges contemporary labor markets. This study integrates job and leisure crafting literature with PCO to explore its relationship with work/non-work outcomes (i.e., thriving at work, self-development behavior, and work–life balance). We examine whether job crafting toward strengths and interests (JC-SI) and leisure crafting mediate the link between PCO and work/non-work outcomes. We also investigate how overqualification might moderate this mediated relationship. Using a matched sample of 235 subordinates and their supervisors from travel agencies in Taipei, we used SEM and PROCESS to test our hypotheses. The results indicated that JC-SI mediated the relationships between PCO and two dependent variables (i.e., thriving at work and self-development behavior). Similarly, leisure crafting mediated the relationship between PCO and personal life enhancement of work. In addition, overqualification enhanced the effects of JC-SI on thriving at work and self-development behavior. This study takes the first step to draw on whole-life perspective to explain how and why PCO leads to work/nonwork outcomes through the dual paths of JC-SI and leisure crafting. Our findings also provide evidence that overqualification magnifies the beneficial effects of JC-SI.

Purpose In value-based health care delivery, radiation oncologists need to compare empiric costs of care delivery with advanced technologies, such as intensity-modulated proton therapy (IMPT) and intensity-modulated radiation therapy (IMRT). We used time-driven activity-based costing (TDABC) to compare the costs of delivering IMPT and IMRT in a case-matched pilot study of patients with newly diagnosed oropharyngeal (OPC) cancer. Materials and Methods We used clinicopathologic factors to match 25 patients with OPC who received IMPT in 2011-12 with 25 patients with OPC treated with IMRT in 2000-09. Process maps were created for each multidisciplinary clinical activity (including chemotherapy and ancillary services) from initial consultation through 1 month of follow-up. Resource costs and times were determined for each activity. Each patient-specific activity was linked with a process map and TDABC over the full cycle of care. All calculated costs were normalized to the lowest-cost IMRT patient. Results TDABC costs for IMRT were 1.00 to 3.33 times that of the lowest-cost IMRT patient (mean ± SD: 1.65 ± 0.56), while costs for IMPT were 1.88 to 4.32 times that of the lowest-cost IMRT patient (2.58 ± 0.39) (P Conclusions In this matched sample, although IMPT was on average more costly than IMRT primarily owing to higher equipment costs, a subset of IMRT patients had similar costs to IMPT patients, owing to greater use of supportive care resources. Multidimensional patient outcomes and TDABC provide vital methodology for defining the value of radiation therapy modalities.

Purpose The purpose of this paper is to examine how the concentration of a specific customer type – governmental customer, affects the pricing of audit services in the USA. Design/methodology/approach This paper applies a standard audit pricing model by regressing audit fees on governmental customer concentration and other common determinants of audit fees. This paper also adopts an instrumental variable approach and performs propensity-score matched sample analyzes to mitigate the potential endogeneity problem. Findings Using data from major customer disclosures of US publicly listed firms from 2000 to 2014, this paper finds that governmental customer concentration is positively associated with audit fees, suggesting that a higher level of governmental customer concentration increases a firm’s audit risks and audit effort. In addition, this paper performs cross-sectional analyzes and show that the association between governmental customer concentration and audit fees is more pronounced for firms with weak internal governance, weak external monitoring and high financial risks. Originality/value This paper furthers the understanding of the interactive relationships in supply chain systems and adds new evidence to the literature on customer concentration. Prior studies on customer concentration typically treat all customer types in a uniform manner. To the knowledge, this is the first study that separates governmental customers from other types of customers in an audit pricing setting. The findings highlight the importance of examining governmental customer concentration when assessing a firm’s audit risks and audit fees.

This study aimed to compare spleen sizes in a hospital and a population sample using ultrasound and define normal values and factors influencing spleen size. Both samples' spleen sizes (n = 1520) were measured using ultrasound under the same conditions. Blood counts and other laboratory parameters were determined under the same conditions in both samples. In the hospital sample (n = 760), the mean spleen size was 114.7 mm, and in the population sample (n = 760), it was 99.1 mm. In both, spleen size in men was significantly higher than in women (p 0.0001) and influenced by body height, weight, and BMI (body mass index) (p 0.0001). In the hospital sample, there was a correlation with higher values for ALT (p = 0.0160), AST (p = 0.0394), AP (p = 0.0482), and ferritin (p = 0.0008) and lower values for HDL (p = 0.0091) and thrombocytes (p 0.0001). In the multivariate analysis, higher values for AP (p = 0.0059) and lower values for hemoglobin (p = 0.0014) and thrombocytes (p = 0.0001) were found. Stratified for sex (men, women), spleen size increased with higher values for ALT (p = 0.0116, p = 0.0113), AST (p = 0.0014, p = 0.0113), and AP (p = 0.0001, p = 0.0012), and with lower values of hemoglobin (p = 0.0057, p = 0.0016), thrombocytes (p 0.0001, p = 0.0003), and albumin (p = 0.0029, p = 0.0432). In women, there was a discordant correlation with red blood cells (p = 0.0005) and a concordant correlation with GGT (p = 0.0241), and in men discordant correlations with cholesterol (p = 0.0010) and HDL (p = 0.0404). The already proven impact of anthropometric data on spleen size was confirmed. The role of laboratory values should be further analyzed.ZIEL: Vergleich der Milzgröße in einem Krankenhaus und einer Bevölkerungsstichprobe unter Verwendung von Ultraschall und Definition von Normalwerten und Faktoren, die die Milzgröße beeinflussen. Die Milzgröße beider Stichproben (n = 1520) wurden unter denselben Bedingungen mittels Ultraschall gemessen. Blutbild und andere Laborparameter wurden in beiden Proben unter den gleichen Bedingungen bestimmt. In der Krankenhaus-Stichprobe (n = 760) lag die mittlere Milzgröße bei 114,7 mm, in der Bevölkerungsstichprobe (n = 760) bei 99,1 mm. In beiden Gruppen war die Milzgröße bei Männern signifikant höher als bei Frauen (p 0,0001) und wurde durch Körpergröße, Gewicht und BMI (Body-Mass-Index) beeinflusst (p 0,0001). In der Krankenhaus-Stichprobe gab es eine Korrelation mit höheren Werten für ALT (p = 0,0160), AST (p = 0,0394), AP (p = 0,0482) und Ferritin (p = 0,0008) und niedrigeren Werten für HDL (p = 0,0091) und Thrombozyten (p 0,0001). In der multivariaten Analyse wurden höhere Werte für AP (p = 0,0059) und niedrigere Werte für Hämoglobin (p = 0,0014) und Thrombozyten (p = 0,0001) gefunden. Stratifiziert nach Geschlecht (Männer, Frauen) stieg die Milzgröße mit höheren Werten für ALT (p = 0,0116, p = 0,0113), AST (p = 0,0014, p = 0,0113) und AP (p = 0,0001, P = 0,0012), und mit niedrigeren Werten für Hämoglobin (p = 0,0057, p = 0,0016), Thrombozyten (p 0,0001, p = 0,0003) und Albumin (p = 0,0029, p = 0,0432). Bei Frauen bestand eine diskordante Korrelation mit den roten Blutkörperchen (p = 0,0005) und eine konkordante Korrelation mit GGT (p = 0,0241), und bei Männern eine diskordante Korrelation mit Cholesterin (p = 0,0010) und HDL (p = 0,0404). Die bereits nachgewiesene Wirkung anthropometrischer Daten auf die Milzgröße wurde bestätigt. Die Rolle der Laborwerte sollte weiter analysiert werden.

Objective To document symptoms and risk factors of obstructive sleep apnea (OSA) in children who have a parent diagnosed with OSA and compare them to an age and sex matched sample where parents are low risk for OSA. Methods We recruited 25 children with a parent diagnosed with OSA (P-OSA) and 29 age and gender matched children from the community whose parents scored low risk for OSA (P-NOSA). Comparisons were made using the OSA-18 questionnaire, anthropometric measurements, and mallampati score. Statistical analysis included t-tests for OSA-18 score and BMI measures and non parametric analysis for mallampati score. OSA-18 domain scores were analysed using T-test and Bonferroni correction for multiple comparisons. Results Fifty-six percent of the P-OSA group had a mallampati score of III/IV compared to 11% in the P-NOSA sample (p = 0.005). There was a significant difference in BMI between the P-OSA sample (mean ± SD 19.5 ± 5.7 kg/m2) and the P-NOSA sample (16.95 ± 2.08 kg/m2, p = 0.002). Forty-four percent of P-OSA children were found to be either overweight or obese (BMI z-score). None of the P-NOSA children fell into this category. No significant difference was found between the P-OSA and P-NOSA samples on the OSA-18 score (P-OSA 36.5 ± 8.1, P-NOSA 29.2 ± 9.1, p = 0.07). Five children in the P-OSA sample scored >60 but no P-NOSA children scored >60. Conclusions This study suggests that children with a parent diagnosed with OSA are more likely to have risk factors of pediatric OSA compared to age and sex matched children of parents without OSA but do not have more symptoms.

Premature discontinuation presents challenges to couple clients and therapists alike. Although couple therapy has demonstrated efficacy and effectiveness, little is known about the mechanisms that contribute to couple therapy completion. This study presents the results of an observational inquiry into the psychotherapeutic processes associated with treatment discontinuance using clinical data. Using observational coding of the Rapid Marital Interaction Coding System (RMICS) researchers sought to examine differences in in-session interactions between couple members in a matched sample of therapy continuers and discontinuers. Results indicate that specifically for female partners, the absence of positive interactions is linked to therapy discontinuation. Clinical implications of these findings are presented and discussed.

PurposeThe authors examine a boundary management tactic for managing the work–family interface: putting family first (PFF). PFF is a boundary management tactic defined as the voluntary behavior of intentionally putting family obligations ahead of work obligations in a way that violates organizational normsDesign/methodology/approachIn Study 1, The authors develop a theoretically derived measure of PFF and distinguish it theoretically and empirically from similar existing constructs, examining convergent and discriminate validity to demonstrate its uniqueness. In Study 2, the authors demonstrate PFF's predictive validity beyond the job incumbent using a three-way matched sample of 226 individuals, including the job incumbent's coworker and spouse.FindingsThe authors established and validated a measure of PFF, developing and replicating the nomological network. PFF crossed over to positively relate to coworker role overload, job frustration and work–family conflict and to spousal stress transmission and relationship tension. Similarly, PFF related negatively to spousal family satisfaction and organizational commitment.Originality/valueThe authors extend the work–family and boundary management literatures by proposing a new form of boundary management, PFF, which is a tactic for managing the work–family interface, and explore how its use influences not only the job incumbent but also the coworker and the spouse.

Introduction Repository corticotropin injection (RCI; Acthar® Gel) is indicated for the treatment of acute exacerbations of multiple sclerosis (MS) in adults. Despite the well-documented clinical and economic benefits of RCI, many patients are denied use of the therapy by third-party payers. This study aims to understand the demographic and clinical characteristics of MS relapse patients who received a prescription for RCI from their physicians and then were either approved or denied treatment by their insurers. The study compares measurable clinical outcomes and healthcare resource utilization (HCRU) between approved and denied cohorts. Methods A retrospective analysis of adults experiencing MS relapse from January 2015 to December 2018 was conducted using a de-identified open-source claims database [Symphony Health Integrated Dataverse® (IDV)]. Patients were identified using ICD codes for MS and considered to have relapsing/remitting type according to established claims-based methodology. Clinical characteristics and HCRU were analyzed during the year preceding (“baseline”) and the year following (“follow-up”) each patient’s index date, defined as the date of a patient’s first approved RCI claim (for patients with ≥ 1 approved claim) or first denied RCI claim (for patients with only denied claims). Baseline characteristics were reported with unadjusted differences and p values indicating the significance of characteristics between the two cohorts. For outcomes, match-adjusted results were reported using propensity matching to account for underlying differences between cohorts. Results The study sample included 1902 MS relapse patients with at least one claim for RCI. At baseline, approved patients were slightly older compared to denied patients (mean age 48.0 vs. 47.2), had higher rates of hemiplegia/paraplegia (6.7% vs. 3.3%), greater mobility impairment (17% vs. 11.5%), more exacerbation episodes (66.2% vs. 59.9%), and a higher number of physical therapy/rehab claims (23.5 vs. 14.0), respectively. Outcomes among the matched sample show an increased use of corticosteroids for patients denied access to RCI compared to approved patients (51.1% vs. 42.4%), more exacerbation episodes (36.6% vs. 28.2%), and an increased number of physical therapy/rehab claims (11.5% vs. 9.9%), respectively. Conclusion The results of this study may aid providers and payers in evaluating scenarios where RCI may be beneficial and improve quality of care for patients experiencing MS relapse.

Background Though cannabis is gaining broader acceptance among society and a noted increase in legalization, little is known regarding its impact on post-operative outcomes. We conducted this study to quantify the relationship between cannabis abuse or dependence (CbAD) on post-operative outcomes after cholecystectomy and appendectomy. Methods Using the 2013-2015 Nationwide Readmissions Database, we identified discharges associated with cholecystectomy or appendectomy from January 2013-August 2015. Patients were grouped by CbAD history. The primary outcomes were length of stay, serious adverse events, home discharge, and 30-day readmission. Propensity-score matching was used to account for differences between groups and all statistics accounted for the matched sample. Results The final sample included 3288 patients with a CbAD history matched 1:1 to patients without a CbAD history (total sample = 6576). After matching, acceptable balance was achieved in clinical characteristics between groups. In the cholecystectomy cohort (n = 1707 pairs), CbAD patients had longer hospitalizations (3.5 versus 3.2 d, P 0.003) and similar rates of serious adverse events (6.1 versus 4.8, P 0.092), home discharge (96.1 vs 96.2, P 0.855), and readmission (8.3 versus 6.9, P 0.137). In the appendectomy cohort (n = 1581 pairs), CbAD patients had longer hospital stays (2.7 versus 2.5 d, P 0.024); more frequent serious adverse events (5.0 versus 3.5, P 0.041); and similar home discharge (96.8 vs 97.3, P 0.404) and readmission (5.4 versus 5.1, P 0.639) rates. Conclusions Patients with a history of CbAD in the cholecystectomy and appendectomy cohorts had slightly longer hospital stays, and patients with a history of CbAD in the appendectomy group displayed a slight increase in adverse events, but otherwise similar clinical outcomes without clinically significant increases in complications compared to patients without this history.

Purpose This paper aims to investigate the attributes and information content of risk reporting in two different institutional and regulatory, namely, Canadian and German, settings during the period surrounding the financial crisis of 2008. Design/methodology/approach For a matched sample of manufacturing firms in the period 2006–2010, this study conducts a detailed content analysis of annual reports to assess and compare the volume and patterns of risk disclosures. Panel regressions are used to explore how risk disclosures related to corporate risk proxies and performance indicators. Findings Over the sample period, Canadian and German firms increase the volume but largely maintain the patterns of risk disclosures. Risk disclosures relate to corporate risk proxies but are not incrementally informative to assess firm performance. Originality/value The paper contributes to research on risk reporting by providing detailed cross-country evidence for a period particularly shaped by significant risk. The findings have implications for the regulation and usefulness of risk reporting.

Background and aims In June 2012, Washington state (USA) implemented Initiative 1183, privatizing liquor sales. As a result, off-premises outlets increased from 330 to over 1400 and trading hours lengthened. Increased availability of liquor may lead to increased consumption. This study examines the impact of Initiative 1183 on alcohol-related adverse health outcomes, measured by inpatient hospitalizations for alcohol-related disorders and accidental injuries. It further assesses heterogeneity by urbanicity, because outlets increased most in metropolitan-urban areas. Design County-by-quarter difference-in-difference linear regression models, estimated statewide and within metropolitan/rural strata. Setting and participants Data are from AHRQ Healthcare Cost and Utilization State Inpatient Database 2010-2014 and HHS Area Health Resource File 2010-2014. Changes in the rates of hospitalizations in the 2.5 years following Initiative 1183 in Washington (n = 39 counties) are compared with changes in Oregon (n = 36 counties). Measurements County rates of hospitalizations per 1000 residents, including all records with any-listed ICD-9 Clinical Classification Software code denoting an alcohol-related disorder, and all records with any-listed external cause of injury code denoting an accidental injury. Findings The increase in the rate of accidental injury hospitalizations in Washington's metropolitan-urban counties was on average 0.289 hospitalizations per 1000 county residents per quarter greater than the simultaneous increase observed in Oregon (P = 0.017). This result was robust to alternative specifications using a propensity score matched sample and synthetic control methods with data from other comparison states. The evidence did not suggest that Initiative 1183 was associated with differential changes in the rate of hospitalizations for alcohol-related disorders in metropolitan-urban (P = 0.941), non-metropolitan-urban (P = 0.162), or rural counties (P = 0.876). Conclusions Implementing Washington's Initiative 1183 (privatizing liquor sales) appears to have been associated with a significant increase in the rate of accidental injury hospitalizations in urban counties in that state but does not appear to be significantly associated with changes in the rate of hospitalizations specifically for alcohol-related disorders within 2.5 years.

Matching is a common approach to covariate adjustment in estimating causal effects in observational studies. It is important to assess covariate balance of the matched samples. This is usually done informally, in ways that have a number of limitations. First, there are many diagnostics, even if covariates are assessed one at a time, which raises multiplicity issues. In addition, joint distributions of covariates, even bivariate distributions, are often ignored. Further, it is an open question whether diagnostics identify the major problems. To address these issues, a formal assessment of covariate balance is developed in the current paper. Unlike the common informal diagnostics, the proposed method compares both marginal distributions and joint distributions of the matched sample with those of the benchmark, complete randomizations. The method controls the probability of falsely identifying a covariate imbalance among many comparisons, yet it has a high probability of correctly detecting and identifying a major problem. An R package met implementing the proposed method is available on CRAN.

This study examined whether a particular type of childhood trauma (CT) is more prevalent in people diagnosed with bipolar disorder than in a matched sample of people diagnosed with schizophrenia an...

In this study, we develop and test the hypothesis that because of opacity, the stock prices of financial firms will cluster on round fractions more than the stock prices of non-financial firms. Indeed, we find that the stock prices of opaque financial firms round on nickels and quarters more than the stock prices of less opaque non-financial firms. These results are robust to a battery of robustness tests that include measuring clustering at different frequencies, different econometric specifications, and different matched sample techniques. To draw stronger causal inferences, we use the passing of the Sarbanes-Oxley (SOX) Act as an exogenous shock to the level of transparency in the financial services sector. We find that price clustering decreases more for financial firms than for non-financial firms during the post-SOX regulation period. We also show that, relative to less opaque financial firms, those financial firms that are more opaque experienced the greatest decline in price clustering during the post-SOX period.

Dairy cows are often diagnosed with fever without showing clinical symptoms of disease. The aim of this study was to investigate changes in feeding, social, and lying behaviors of cows with fever but without clinical disease, as compared with healthy cows. After parturition, dairy cows of mixed parities were housed in a dynamic group of 20. In the freestall pen, cows had access to 12 electronic feed bins, 2 electronic water bins, and 24 lying stalls. Feeding and social behaviors were recorded using the electronic feed bins, and lying behaviors were measured using electronic data loggers attached to the cow. Rectal body temperature was assessed on a daily basis, and fever defined as a body temperature >39.5°C. All cows were examined for metritis every third day after calving, and all other diseases (e.g., mastitis, ketosis) were diagnosed as per farm protocol. Cows with multiple days of fever (n = 8) and cows with 1 d of fever (n = 18) that were not diagnosed with a clinical disease were compared with a matched sample of healthy cows (i.e., cows that were not clinically ill and never had a fever recorded) of the same parity (categorized as primiparous vs. multiparous). Feeding, social, and lying behaviors were compared for the first 2 d of fever in cows with multiple days of fever, and the day of fever in cows with 1 d of fever. Cows of both fever groups spent less time feeding compared with controls (135 vs. 181 ± 7.6 min/d for multiple fever days, and 158 vs. 185 ± 9.7 min/d for 1 d of fever). Cows with 1 d of fever ate at a faster rate (109 vs. 91 ± 5 g/min) and had a lower number of replacements at the feed bunk (actor replacements: 9.7 vs. 14.6 ± 1.7 no./d; reactor replacements: 11.1 vs. 15.9 ± 1.6 no./d) compared with healthy controls. Overall, cows with fever showed behavioral changes such as decreased feeding time that are consistent with sickness responses described in other species.

Cryptococcus neoformans (C. neoformans) is an opportunistic fungal pathogen to humans, which can be acquired from environmental sources. Its most important virulence factor is its polysaccharide capsule, which can be used for diagnostic tests that identify the cryptococcal antigen (CrAg). The CrAg lateral flow assay (LFA) is a dipstick immunochromatographic assay with high sensitivity and specificity; however, several false-negative cases have been reported. Here, we present a case of a false-negative serum CrAg LFA, in which the blood culture from a matched sample was positive for C. neoformans, thus demonstrating the postzone phenomenon.

We explore the impact of supervision on the riskiness, profitability, and growth of U.S. banks. Using data on supervisors' time use, we demonstrate that the top‐ranked banks by size within a supervisory district receive more attention from supervisors, even after controlling for size, complexity, risk, and other characteristics. Using a matched sample approach, we find that these top‐ranked banks that receive more supervisory attention hold less risky loan portfolios, are less volatile, and are less sensitive to industry downturns, but do not have lower growth or profitability. Our results underscore the distinct role of supervision in mitigating banking sector risk.

In this article, we investigate whether academic technology-based knowledge crosses university boundaries or remains trapped inside the ivory tower. To do so, we rely on a matched sample approach to compare the spillovers generated by academic and firm patents using measures that take into account knowledge spilling-in and knowledge spilling-out of academia. Although it is true that knowledge exchanges among universities may inflate the overall spillovers of university patents vis-à-vis firm patents, our results indicate that university patents generate more spillovers than a comparable sample of matched corporate patents, even when knowledge flows among universities are not regarded as spillovers. This suggests that, in our sample, firm technologies more frequently rely on academic patents than on technologies from other corporations. In addition, we find that the gap between university and industry spillovers differs across industries, with industries where patents are important for appropriating returns from R&D (i.e. more economically valuable), such as drugs, presenting a smaller gap than in industries with complex technologies (where firms have strong incentives to patent aggressively), such as computers. Finally, we show that industry patents generate more spillovers locally and that academic knowledge spillovers are less geographically localized than those of corporate research.

ObjectiveHospitals participating in the Medicare Shared Savings Program (MSSP) share with the Centers for Medicare and Medicaid Services (CMS) the savings generated by reduced cost of care. Our aim was to determine whether MSSP is associated with changes in readmissions and mortality for Medicare patients hospitalized with ischemic stroke, and whether MSSP has a different impact on safety net hospitals (SNHs) compared to non-SNHs.MethodsThis study was based on the CMS Hospital Compare data for risk-standardized 30-day readmission and mortality rates for Medicare patients hospitalized with ischemic strokes between 2010 and 2017. With a propensity score–matched sample, hospital-level difference-in-difference analysis was used to determine whether MSSP was associated with changes in hospital readmission and mortality as well as to examine the impact of MSSP on SNHs compared to non-SNHs.ResultsMSSP-participating hospitals had slightly greater reductions in readmission rates compared to matched nonparticipating hospitals (difference, 0.25 percentage points; 95% confidence interval [CI], −0.42 to −0.08). Mortality rates decreased among all hospitals, but mortality reduction was not significantly different between MSSP-participating hospitals and matched hospitals (difference, 0.06 percentage points; 95% CI, −0.28 to 0.17). Prior to MSSP, readmission rates in SNHs were higher compared to non-SNHs, but MSSP did not have significantly different impact on hospital readmission and mortality rates for SNHs and non-SNHs.ConclusionMSSP led to slightly fewer readmissions without increases in mortality for Medicare patients hospitalized with ischemic stroke. Similar reductions in readmission rates were observed in SNHs and non-SNHs participating in MSSP, indicating persistent gaps between SNHs and non-SNHs.

This study investigates the extent to which migrants’ embeddedness in two formal social protection systems (country of origin and host country) influences the resources they exchange in their informal supportive relationships. I analyze the support networks of a matched sample of Turkish migrants in Germany and their significant others in Turkey to illuminate the conditions and meaning of reciprocal resource exchanges, finding that both migrants and nonmigrants perceive formal social protection offered by Germany as superior to that of Turkey. I show that those perceptions have implications for how financial support is exchanged with the family but have less impact on friendships. These implications for family included unequal power relationships, changes in equity among siblings and family, different valuation processes of resources, and thus, (reciprocal) exchanges.

The hedonic imputation method allows characteristic shadow prices to evolve over time. These shadow prices are used to construct matched samples of predicted prices, which are inserted into standard price index formulas. We use a spatio-temporal model to improve the method’s effectiveness on housing data at higher frequencies. The problem is that at higher frequencies, there may not be enough observations per period to reliably estimate the characteristic shadow prices. In such cases, the reliability of the hedonic imputation method is improved by using a state-space formulation which yields estimates of the shadow prices that are weighted sums of previous periods’ information. In addition, the state-space representation of the model includes a geospatial spline surface which significantly reduces the number of parameters to be estimated when compared to the standard practice of including postcode dummies in the model. Empirically, using a novel criterion, we show that in higher frequency comparisons, our hedonic method outperforms competing alternatives.

In recent years, community school (CS) reform efforts have been established and implemented as a method of realizing comprehensive school reform in under-performing school districts. This study inv...

Cet article étudie l’impact du microcrédit au Brésil. Nous utilisons la méthode d’appariemment sur score de propension sur des données primaires originales issues de résultats commerciaux et personnels pour comparer les clients de longue date de la BNDES - la plus grande banque de développement appartenant au gouvernement du Brésil - à un échantillon apparié de clients plus récents. Sur la base de données administratives ainsi que de données d’une enquête auprès de 2 107 clients des régions Sud et Nord-Est du Brésil, les résultats ne montrent aucun impact significatif sur les revenus, la création d’emplois, l’accès au crédit et la structuration des entreprises, avec une exception au sein des municipalités les plus pauvres du Nord-Est, où le microcrédit a montré des effets positifs. This paper studies the impact of microcredit in Brazil. We use a propensity score matching on original primary data on business and personal outcomes to compare veteran clients of BNDES - Brazil’s largest government-owned development bank - to a matched sample of more recent clients. Based on administrative data as well as data from a survey of 2107 clients from the South and Northeast regions of Brazil, the findings show no significant impacts on income, employment generation, access to credit, and business formalization, except for the poorest Municipalities of the Northeast, where microcredit presented positive effects.

We examine the personal investment decisions of 60,000 households following a cancer diagnosis. To create a control group that minimizes the likelihood that the results are confounded by lifestyle factors, we rely on households diagnosed with the same diagnosis but a few years later. Our estimates show that a cancer diagnosis reduces households’ willingness to take risks with their financial wealth. We use the vast heterogeneity among cancers regarding its impact on life expectancy (LE) and income to analyze through which channels cancer impact risk-taking. We find that cancers that have a greater impact on LE and income cause a larger reduction in risk-taking. These two channels account for about 40–90% of the estimated effects of cancer on personal investment decisions. We do not find any association between having dealt with cancer many years ago and current portfolio choices.

Although several studies have attempted to capture civic learning, philanthropic attitudes, career outcomes, and behavioral intentions immediately following the completion of an undergraduate student philanthropy service-learning course, there is a lack of research on the sustained effects of this high-impact practice. This study assessed the long-term effects of a philanthropy-based service-learning program compared with a matched sample of alumni who did not participate in a philanthropy-based course. Alumni completed surveys assessing demographics, current rates of volunteerism, charitable giving, and engagement within the nonprofit sector. They also completed the Civic Engagement Scale and the Civic Minded Graduate Scale. Philanthropy program alumni focus groups were conducted. The two groups did not differ on behavioral outcomes such as volunteerism and philanthropic giving; however, significant differences were found for civic attitudes and dispositions. Recommendations for best practices for philanthropy-based course design and implications for nonprofit education and leadership programs are discussed.Subscribe to JNEL

This study examines the timeliness of XBRL data filings. To be timely, the XBRL data must be filed concurrently with the 10-K filing. Using a matched sample of non-timely (NT) and timely XBRL filers over the period 2009–2016, we investigate factors associated with the timeliness of XBRL. We find that NT XBRL filings are more likely when the filing is more complex and when the filer changes auditors. In contrast, using a service provider with more experience and a Big 4 auditor are positively associated with XBRL filing timeliness. NT XBRL filers also experience more negative market-adjusted stock returns compared to the timely XBRL filers. These findings may inform regulators about the implementation of XBRL. Regulators may want to consider these factors in future efforts to use technological advances to improve accessibility to information. JEL Classifications: M15; M48.

PurposeThe purpose of this paper is to comprehensively explore the association between low self-control and college student retention.Design/methodology/approachCross-sectional survey data were obtained from 369 undergraduate students in the USA and combined with follow-up data on retention. Factor analysis was used to develop and validate the abbreviated eight-item low self-control instrument. Propensity score matching, an analytic technique that permits the assertion of causality without the need for experimental design, was used to examine the relationship between low self-control and second-semester college retention. Use of propensity score matching permitted the pairing of survey respondents under the defined circumstance of low self-control with those respondents not having low self-control under multiple relevant covariates.FindingsThe results showed a relationship between low self-control and college retention. Specifically, in the matched sample, those students with low self-control were 8 percent less likely to be retained at the institution at the onset of the second year than their counterparts with higher self-control.Practical implicationsThe results of the study prompt the important question of how colleges and universities can alter their structures and processes to better support students with low self-control. Key managerial and administrative implications from the findings of this study revolve around the recognition, motivation, and subsequent performance appraisals of those students with low self-control.Originality/valueThis study extends the quite limited research on how low self-control correlates with retention and subsequently offers insights on how to further support students with low self-control as a way to improve retention outcomes. Additionally, the validated eight-item survey provides a quick, low-cost assessment tool for interested researchers and managers.

Parenthood remains one of the most gender-typed social roles in adulthood. Given gender inequality in parenting, it has been very surprising to find that parental burnout affects both mothers and fathers in equal proportion. The aim of the present study was to properly test gender effects in the nature, average level, antecedents, and consequences of parental burnout. Data were collected from a strictly matched sample of about 900 French- and English-speaking mothers and fathers. We found measurement invariance across genders and a higher average level of parental burnout among mothers than fathers. We also found the same antecedent mechanism at work in both mothers and fathers (i.e., an imbalance of risks over resources in the specific context of parenting), but fathers were seen to be more vulnerable to such imbalance in this specific area. Burnout ultimately was seen to have more detrimental consequences for fathers than for mothers. In particular, escape and suicidal ideations as well as neglectful behaviors toward children were more common in burned-out fathers than in mothers. Our findings are discussed together with considerations of the gender-role socialization process, social roles as shared norms, and the salience of parental identity in women and men.

Home Instruction for Parents of Preschool Youngsters (HIPPY) is a home-based intervention for parent engagement and kindergarten readiness. Using a quasi-experimental design, this research sought to determine whether the HIPPY intervention increased children's likelihood of passing the Florida Kindergarten Readiness Screener and being promoted to the first grade. The sample included 730 children, of whom 379 participated in the intervention group (i.e., HIPPY) and 351 were identified for the comparison group using propensity score matching techniques. Among families at risk due to poverty and limited English language proficiency, the odds of passing the Florida Kindergarten Readiness Screener were almost two times greater for children whose parents participated in the HIPPY program and their odds of being promoted to the first grade were five times greater than a matched sample of non-participants. This research provides evidence of a successful HIPPY scale-up in real-world contexts and among a diverse sample. The discussion includes implications for policy and directions for future research.

Transitioning to university can be anxiety-provoking for all students. The relationship between social anxiety, autistic traits and students’ social network structure, and perceived support is poorly understood. This study used a group-matched design where autistic students (n = 28) and typically developing students (n = 28) were matched on sex, age (17–19 years), ethnicity, pre-university academic performance and degree subject at university. Autistic students reported greater transition to university worries, and a smaller social network size compared to typically developing students, though perceived similar levels of support from their social networks. Autistic and typically developing students showed differential patterns of association with both autistic traits and social anxiety. Broader clinical and practical implications of findings are discussed., Lay Abstract Transitioning to university can be anxiety-provoking for all students. The academic, daily living and social difficulties can become magnified for autistic students when considered alongside the social difficulties associated with autism, as well as higher levels of co-occurring social anxiety. Although previous studies report poor transition outcomes and retention rates for autistic students, it is unclear whether: (1) the academic, daily living and socialisation difficulties reported are unique to autistic students; (2) whether there are differences in students’ social networks at university, as well as their perceived level of support provided by network members; and (3) to what extent these difficulties may be accounted for by social anxiety found in both autistic and typically developing (TD) students when transitioning to university. This study compared a group of autistic students transitioning to university against a group of TD students who are similar in age, sex, academic performance prior to starting university and subject of study at university. Autistic students were found to be more socially anxious, more worried about different aspects of university life. Autistic students had a smaller social network compared to TD students, though both groups perceived similar levels of support from their social networks. Higher levels of social anxiety common to both groups, not autistic traits, was associated with greater distress in daily living and socialisation at university. University stakeholders may consider providing more psychoeducation and support around social anxiety for both autistic and TD students transitioning to university, to improve transition outcomes for all students.

I apply context-emergent turnover (CET) theory to investigate how different organizational characteristics moderate the effect of executive turnover on firm performance. I suggest and investigate different organizational characteristics as contextual factors. I find that executive turnover reduces future sales and employment growth, and show that three organizational characteristics (the firm's age, top management tenure, and employee tenure) moderate this effect. These results contribute to our understanding of the role of context in moderating executive turnover. Previous studies that examined the performance effects of executive turnover have often struggled to prove the causality between this event and a firms' post-turnover performance conclusively. The problem is that executive turnover is often correlated with a firm's current performance and expected future challenges. I address this endogeneity problem by exploiting the exogenous variation in firms' performances following 516 top managers' unexpected deaths. I use a matched sample to investigate which organizational characteristics that mitigate the negative effect on the firms' subsequent performances resulting from these executive turnovers. I obtained this sample randomly from a comprehensive dataset containing yearly observations of all Danish firms from 1995 to 2007.

This paper examines the impact of economic and development zones (EDZs) on the productivity of incumbent firms in China. To deal with the selection issue, I first take into account potentially different selection mechanisms across two popular types of EDZs—economic and technological development zones (ETDZs) and high‐tech development zones (HTDZs)—by relying on multiple treatment propensity scores matching techniques. Next, I apply the difference‐in‐differences estimator to the matched sample and conduct an event study analysis. The results show that the respective effects of ETDZs and HTDZs on firm productivity are positive, but subject to a nonlinear trend over time. The size of the productivity gains depends critically on the type of EDZ, however. A new HTDZ (ETDZ) leads to an average productivity gain of up to 30.2% (18.4%) for incumbent firms in the 5 years after the zone was created. These findings suggest that the size of productivity spillovers for spatially targeted firms differ quite significantly depending on the strategic development and policy goals of the EDZ: HTDZs that focus on promoting indigenous‐based factors of learning lead to higher productivity spillovers compared with ETDZs that focus on promoting extra‐local linkages.

This paper analyzes the relationship between pre-IPO growth and the post-IPO long-run performance for venture capital (VC)-backed firms. Our results show that the effect of pre-IPO growth on post-IPO long-run performance is positive, but is attenuated by venture capital in a matched sample. Focusing on VC-backed IPO firms, we find an inverted-U relationship between pre-IPO growth and post-IPO long-run performance. In addition, our baseline results continue to hold in a variety of settings, including post-IPO profitability performance and ownership divisions of venture capital. We explore one underlying interpretation through which post-IPO long-run performance exhibits a reversal when pre-IPO growth increases to a saturation point: VC-backed firms tend to engage in accounting fraud due to the incentives from some opportunistic VCs to take firms public earlier.

I investigate the impact of the voluntary adoption of clawback provisions on managerial ability and predict that clawback provisions will motivate managers to exert more efforts following the adoption of clawback and these efforts will be in the form of an increased managerial efficiency. Using a propensity score matched sample of firms, I find a significant positive association between voluntary clawback adoption and the change in both rank and score of managerial ability. My study highlights the unintended consequences of clawback provisions on CEO's behavior and contributes to the on‐going debate on the importance of proactively and carefully drafting clawback policies, further signifying the importance of the SEC's efforts (Rule 10D‐1) to enforce clawback policies.

Objectives To evaluate postural regulation and stability among patients who underwent anterior cruciate ligament reconstruction (ACLR) and rehabilitation over a two-year follow-up period. Design Longitudinal; Setting Biomechanics laboratory; Participants 30 ACLR patients (32.0 ± 12.2 years, 14 males) with isolated ACL rupture. Main outcome measures Postural regulation was tested before ACLR, as well as at six-weeks, twelve-weeks, six-months, one-year and two-years post-ACLR and standardized rehabilitation. Postural regulation was measured for stability indicator (ST), weight distribution index (WDI), synchronization (foot coordination) and sway intensities (postural subsystems). Results Significant time effects (pre-vs. two-years postoperative) were found for WDI (ηp2 = 0.466), synchronization (ηp2 = 0.368), mediolateral weight distribution (ηp2 = 0.349), ST (ηp2 = 0.205), visual/nigrostriatal systems (ηp2 = 0.179) and peripheral-vestibular system (ηp2 = 0.102). The largest difference (preoperative: ηp2 = 0.180) to the matched sample was calculated for WDI. The most significant differences to the matched sample were observed for ST (preoperative: ηp2 = 0.126; six-weeks postoperative: ηp2 = 0.103) and WDI (preoperative: ηp2 = 0.180; six-weeks postoperative: ηp2 = 0.174). Conclusion ACLR and rehabilitation influence postural subsystems, postural stability, weight distribution and foot synchronization. Normalization of mediolateral weight distribution requires one year following ACLR. The ACLR leads to a suppression of the somatosensory and cerebellar system which was compensated by a higher activity of the visual and nigrostriatal systems.

Much has been written about intimate partner homicide (IPH), but empirical examinations have been less rigorous and mostly descriptive in nature. The purpose of this paper is to provide an exploration of the characteristics of fatal intimate partner violence (IPV) cases.,A direct comparison of fatal IPHs with both a matched sample of non-fatal IPV cases and a random selection of non-fatal IPV cases is made on a number of offence, offender, victim characteristics and risk-relevant variables.,Despite assertions that domestic homicide is different than domestic violence, in general, few notable differences emerged among the groups. Prior domestic incidents differed between the matched fatal and non-fatal cases, where a greater proportion of the homicide perpetrators had a prior domestic incident. Other differences that were found revealed that more non-fatal perpetrators had substance abuse problems, younger victims and been unemployed at the time of the offence. However, differences were minimal when fatal and non-fatal IPV perpetrators were matched on demographic features and criminal history.,This study highlights that there may be few features that distinguish IPH and non-fatal violence. Rather than be distracted with searching for risk factors predictive of fatality, we should evaluate IPV risk using broad-based approaches to determine risk for reoffending and overall severity of reoffending.