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1. Uracil-5-yl O-Sulfamate: An Illusive Radiosensitizer. Pitfalls in Modeling the Radiosensitizing Derivatives of Nucleobases

Author

Stephan Denifl, Janusz Rak, Mateus Salomão Rodrigues Costa, Paulina Spisz, Dariusz Wyrzykowski, Artur Sikorski, Karina Falkiewicz, Eugene Arthur-Baidoo, Witold Kozak, Samanta Makurat, Magdalena Zdrowowicz, Lidia Chomicz-Mańka, and Patrick Ziegler

Subjects
Radiosensitizer, 010304 chemical physics, Chemistry, medicine.medical_treatment, Uracil, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Surfaces, Coatings and Films, Nucleobase, Gas phase, Ionizing radiation, Radiation therapy, chemistry.chemical_compound, 0103 physical sciences, Materials Chemistry, medicine, Electron attachment, Physical and Theoretical Chemistry
Abstract

Efficient radiotherapy requires the concomitant use of ionizing radiation (IR) and a radiosensitizer. In the present work uracil-5-yl O-sulfamate (SU) is tested against its radiosensitizing potenti...

Published
2020

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