33,879 results on '"Matheson A."'
Search Results
2. Mixed-precision numerics in scientific applications: survey and perspectives
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Kashi, Aditya, Lu, Hao, Brewer, Wesley, Rogers, David, Matheson, Michael, Shankar, Mallikarjun, and Wang, Feiyi
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Computer Science - Computational Engineering, Finance, and Science ,Mathematics - Numerical Analysis ,65Y10 ,J.2 - Abstract
The explosive demand for artificial intelligence (AI) workloads has led to a significant increase in silicon area dedicated to lower-precision computations on recent high-performance computing hardware designs. However, mixed-precision capabilities, which can achieve performance improvements of 8x compared to double-precision in extreme compute-intensive workloads, remain largely untapped in most scientific applications. A growing number of efforts have shown that mixed-precision algorithmic innovations can deliver superior performance without sacrificing accuracy. These developments should prompt computational scientists to seriously consider whether their scientific modeling and simulation applications could benefit from the acceleration offered by new hardware and mixed-precision algorithms. In this article, we review the literature on relevant applications, existing mixed-precision algorithms, theories, and the available software infrastructure. We then offer our perspective and recommendations on the potential of mixed-precision algorithms to enhance the performance of scientific simulation applications. Broadly, we find that mixed-precision methods can have a large impact on computational science in terms of time-to-solution and energy consumption. This is true not only for a few arithmetic-dominated applications but also, to a more moderate extent, to the many memory bandwidth-bound applications. In many cases, though, the choice of algorithms and regions of applicability will be domain-specific, and thus require input from domain experts. It is helpful to identify cross-cutting computational motifs and their mixed-precision algorithms in this regard. Finally, there are new algorithms being developed to utilize AI hardware and and AI methods to accelerate first-principles computational science, and these should be closely watched as hardware platforms evolve., Comment: Submitted to IJHPCA
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- 2024
3. DAmodel: Hierarchical Bayesian Modelling of DA White Dwarfs for Spectrophotometric Calibration
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Boyd, Benjamin M., Narayan, Gautham, Mandel, Kaisey S., Grayling, Matthew, Berres, Aidan, Li, Mai, Do, Aaron, Saha, Abhijit, Axelrod, Tim, Matheson, Thomas, Olszewski, Edward W., Bohlin, Ralph C., Calamida, Annalisa, Holberg, Jay B., Hubeny, Ivan, Mackenty, John W., Rest, Armin, Sabbi, Elena, and Stubbs, Christopher W.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Solar and Stellar Astrophysics ,Statistics - Applications - Abstract
We use hierarchical Bayesian modelling to calibrate a network of 32 all-sky faint DA white dwarf (DA WD) spectrophotometric standards ($16.5 < V < 19.5$) alongside the three CALSPEC standards, from 912 \r{A} to 32 $\mu$m. The framework is the first of its kind to jointly infer photometric zeropoints and WD parameters ($\log g$, $T_{\text{eff}}$, $A_V$, $R_V$) by simultaneously modelling both photometric and spectroscopic data. We model panchromatic HST/WFC3 UVIS and IR fluxes, HST/STIS UV spectroscopy and ground-based optical spectroscopy to sub-percent precision. Photometric residuals for the sample are the lowest yet yielding $<0.004$ mag RMS on average from the UV to the NIR, achieved by jointly inferring time-dependent changes in system sensitivity and WFC3/IR count-rate nonlinearity. Our GPU-accelerated implementation enables efficient sampling via Hamiltonian Monte Carlo, critical for exploring the high-dimensional posterior space. The hierarchical nature of the model enables population analysis of intrinsic WD and dust parameters. Inferred SEDs from this model will be essential for calibrating the James Webb Space Telescope as well as next-generation surveys, including Vera Rubin Observatory's Legacy Survey of Space and Time, and the Nancy Grace Roman Space Telescope., Comment: 32 pages, 24 figures, 5 tables, submitted to MNRAS
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- 2024
4. Faint white dwarf flux standards: data and models
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Bohlin, Ralph C., Deustua, Susana, Narayan, Gautham, Saha, Abhijit, Calamida, Annalisa, Gordon, Karl D., Holberg, Jay B., Hubeny, Ivan, Matheson, Thomas, and Rest, Armin
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Fainter standard stars are essential for the calibration of larger telescopes. This work adds to the CALSPEC (calibration spectra) database 19 faint white dwarfs (WDs) with all-sky coverage and V magnitudes between 16.5 and 18.7. Included for these stars is new UV (ultraviolet) HST (Hubble Space Telescope) STIS (Space Telescope Imaging Spectrometer) spectrophotometry between 1150 and 3000~\AA\ with a resolution of $\sim$500. Pure hydrogen WD models are fit to these UV spectra and to six-band HST/WFC3 (Wide Field Camera 3) photometry at 0.28 to 1.6~\micron\ to construct predicted model SEDs (spectral energy distributions) covering wavelengths from 900~\AA\ to the JWST (James Webb Space Telescope) limit of 30~\micron\ using well-established CALSPEC procedures for producing flux standards with the goal of 1\% accuracy.
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- 2024
5. Lung cell toxicological effects of 3D printer aerosolized filament byproducts
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Beard, Jonathan M., Royer, Brooke M., Hesita, Jacob M., Byrley, Peter, Lewis, Ashley, Hadynski, John, Matheson, Joanna, Al-Abed, Souhail R., and Sayes, Christie M.
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- 2025
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6. Evidence-based Gambling Interventions for People Experiencing Homelessness: A call to Action
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Matheson, Flora I., Hahmann, Tara, McLuhan, Arthur, Woodhall-Melnik, Julia, and Zafar, Shahroze
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- 2024
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7. Rare Earth Metal Production Through Metallothermic Reduction: Preparation of Anhydrous Salt and Reduction Using Sodium Metal
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Tanvar, Himanshu, Aksenova, Diana, Gordon, Jared, VanLieshout, Richard, Keller, Philip, O’Kelley, Brock, Matheson, Andrew, Siddall, Jon, Mishra, Brajendra, Lazou, Adamantia, editor, Meskers, Christina, editor, Olivetti, Elsa, editor, Diaz, Fabian, editor, and Gökelma, Mertol, editor
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- 2025
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8. DECam Multi-Messenger Astrophysics Pipeline. I. from Raw Data to Single-Exposure Candidates
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Fu, Shenming, Matheson, Thomas, Meisner, Aaron, Zhang, Yuanyuan, Vicencio, Sebastián, and Saul, Destry
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We introduce a pipeline that performs rapid image subtraction and source selection to detect transients, with a focus on identifying gravitational wave optical counterparts using the Dark Energy Camera (DECam). In this work, we present the pipeline steps from processing raw data to identification of astrophysical transients on individual exposures. We process DECam data and build difference images using the Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) Science Pipelines software, and we use flags and principal component analysis to select transients on a per-exposure basis, without associating the results from different exposures. Those candidates will be sent to brokers for further classification and alert distribution. We validate our pipeline using archival exposures that cover various types of objects, and the tested targets include a kilonova (GW170817), supernovae, stellar flares, variable stars (in a resolved galaxy or the Milky Way Bulge), and serendipitous objects. Overall, the data processing produces clean light curves that are comparable with published results, demonstrating the photometric quality of our pipeline. Real transients can be well selected by our pipeline when sufficiently bright (S/N $\gtrsim15$). This pipeline is intended to serve as a tool for the broader research community. Although this pipeline is designed for DECam, our method can be easily applied to other instruments and future LSST observations., Comment: 37 pages, 25 figures, 5 tables; revised and accepted for publication in AJ
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- 2024
9. Anomaly Detection and Approximate Similarity Searches of Transients in Real-time Data Streams
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Aleo, P. D., Engel, A. W., Narayan, G., Angus, C. R., Malanchev, K., Auchettl, K., Baldassare, V. F., Berres, A., de Boer, T. J. L., Boyd, B. M., Chambers, K. C., Davis, K. W., Esquivel, N., Farias, D., Foley, R. J., Gagliano, A., Gall, C., Gao, H., Gomez, S., Grayling, M., Jones, D. O., Lin, C. -C., Magnier, E. A., Mandel, K. S., Matheson, T., Raimundo, S. I., Shah, V. G., Soraisam, M. D., de Soto, K. M., Vicencio, S., Villar, V. A., and Wainscoat, R. J.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We present LAISS (Lightcurve Anomaly Identification and Similarity Search), an automated pipeline to detect anomalous astrophysical transients in real-time data streams. We deploy our anomaly detection model on the nightly ZTF Alert Stream via the ANTARES broker, identifying a manageable $\sim$1-5 candidates per night for expert vetting and coordinating follow-up observations. Our method leverages statistical light-curve and contextual host-galaxy features within a random forest classifier, tagging transients of rare classes (spectroscopic anomalies), of uncommon host-galaxy environments (contextual anomalies), and of peculiar or interaction-powered phenomena (behavioral anomalies). Moreover, we demonstrate the power of a low-latency ($\sim$ms) approximate similarity search method to find transient analogs with similar light-curve evolution and host-galaxy environments. We use analogs for data-driven discovery, characterization, (re-)classification, and imputation in retrospective and real-time searches. To date we have identified $\sim$50 previously known and previously missed rare transients from real-time and retrospective searches, including but not limited to: SLSNe, TDEs, SNe IIn, SNe IIb, SNe Ia-CSM, SNe Ia-91bg-like, SNe Ib, SNe Ic, SNe Ic-BL, and M31 novae. Lastly, we report the discovery of 325 total transients, all observed between 2018-2021 and absent from public catalogs ($\sim$1% of all ZTF Astronomical Transient reports to the Transient Name Server through 2021). These methods enable a systematic approach to finding the "needle in the haystack" in large-volume data streams. Because of its integration with the ANTARES broker, LAISS is built to detect exciting transients in Rubin data., Comment: 44 pages (68 pages with Appendix), 15 figures, accepted to ApJ
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- 2024
10. Beyond Point Masses. II. Non-Keplerian Shape Effects are Detectable in Several TNO Binaries
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Proudfoot, Benjamin C. N., Ragozzine, Darin A., Thatcher, Meagan L., Grundy, Will, Spencer, Dallin J., Alailima, Tahina M., Allen, Sawyer, Bowden, Penelope C., Byrd, Susanne, Camacho, Conner D., Campbell, Gibson H., Carlisle, Edison P., Christensen, Jacob A., Christensen, Noah K., Clement, Kaelyn, Derieg, Benjamin J., Dille, Mara K., Dorrett, Cristian, Ellefson, Abigail L., Fleming, Taylor S., Freeman, N. J., Gibson, Ethan J., Giforos, William G., Guerrette, Jacob A., Haddock, Olivia, Hammond, S. Ashton, Hampson, Zachary A., Hancock, Joshua D., Harmer, Madeline S., Henderson, Joseph R., Jensen, Chandler R., Jensen, David, Jensen, Ryleigh E., Jones, Joshua S., Kubal, Cameron C., Lunt, Jacob N., Martins, Stephanie, Matheson, McKenna, Maxwell, Dahlia, Morrell, Timothy D., Myckowiak, McKenna M., Nelsen, Maia A., Neu, Spencer T., Nuccitelli, Giovanna G., Reardon, Kayson M., Reid, Austin S., Richards, Kenneth G., Robertson, Megan R. W., Rydalch, Tanner D., Scoresby, Conner B., Scott, Ryan L., Shakespear, Zacory D., Silveira, Elliot A., Steed, Grace C., Suggs, Christiana Z., Suggs, Garrett D., Tobias, Derek M., Toole, Matthew L., Townsend, McKayla L., Vickers, Kade L., Wagner, Collin R., Wright, Madeline S., and Zappala, Emma M. A.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
About 40 transneptunian binaries (TNBs) have fully determined orbits with about 10 others being solved except for breaking the mirror ambiguity. Despite decades of study almost all TNBs have only ever been analyzed with a model that assumes perfect Keplerian motion (e.g., two point masses). In reality, all TNB systems are non-Keplerian due to non-spherical shapes, possible presence of undetected system components, and/or solar perturbations. In this work, we focus on identifying candidates for detectable non-Keplerian motion based on sample of 45 well-characterized binaries. We use MultiMoon, a non-Keplerian Bayesian inference tool, to analyze published relative astrometry allowing for non-spherical shapes of each TNB system's primary. We first reproduce the results of previous Keplerian fitting efforts with MultiMoon, which serves as a comparison for the non-Keplerian fits and confirms that these fits are not biased by the assumption of a Keplerian orbit. We unambiguously detect non-Keplerian motion in 8 TNB systems across a range of primary radii, mutual orbit separations, and system masses. As a proof of concept for non-Keplerian fitting, we perform detailed fits for (66652) Borasisi-Pabu, possibly revealing a $J_2 \approx 0.44$, implying Borasisi (and/or Pabu) may be a contact binary or an unresolved compact binary. However, full confirmation of this result will require new observations. This work begins the next generation of TNB analyses that go beyond the point mass assumption to provide unique and valuable information on the physical properties of TNBs with implications for their formation and evolution., Comment: Accepted to AJ
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- 2024
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11. Contrast-enhanced mammography for surveillance in women with a personal history of breast cancer
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Matheson, Julia, Elder, Kenneth, Nickson, Carolyn, Park, Allan, Mann, Gregory Bruce, and Rose, Allison
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- 2024
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12. Palliative Care Referral Patterns and Implications for Standardization in Cardiac ICU
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Madni, Arshia, Matheson, Jocelyn, Linz, Amanda, Dalgo, Austin, Siddique, Rumana, and Merlocco, Anthony
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- 2024
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13. Breaking up with belongings: a pilot randomized controlled trial of an unguided web-based program to reduce overconsumption
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Norberg, Melissa M., Matheson, Angelica C., Visvalingam, Shanara, King, Ronan D., Olivier, Jake, David, Jonathan, and McLellan, Lauren F.
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- 2024
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14. Primary Non-Inversion Shallow Tillage Versus Moldboard Plowing Prior to Growing Potatoes: Short-Term Impacts on Potato Yield and Soil Properties in Eastern Canada
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Nyiraneza, Judith, Fraser, Tandra D., Murnaghan, Danielle, Matheson, Jessica, Arnold, Stephanie, Stiles, Kyra, Chen, Dahu, Peters, Rick, Khakbazan, Mohammad, and Barrett, Ryan
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- 2024
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15. Windows on the Universe: Establishing the Infrastructure for a Collaborative Multi-messenger Ecosystem
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The 2023 Windows on the Universe Workshop White Paper Working Group, Ahumada, T., Andrews, J. E., Antier, S., Blaufuss, E., Brady, P. R., Brazier, A. M., Burns, E., Cenko, S. B., Chandra, P., Chatterjee, D., Corsi, A., Coughlin, M. W., Coulter, D. A., Fu, S., Goldstein, A., Guy, L. P., Hooper, E. J., Howell, S. B., Humensky, T. B., Kennea, J. A., Jarrett, S. M., Lau, R. M., Lewis, T. R., Lu, L., Matheson, T., Miller, B. W., Narayan, G., Nikutta, R., Rajagopal, J. K., Rest, A., Ruiz-Rocha, K. M., Runnoe, J., Sand, D. J., Santander, M., Solares, H. A. A., Soraisam, M. D., Street, R. A., Tohuvavohu, A., Vieira, J., Vieregg, A., Vigeland, S. J., Vitale, S., White, N. E., Wyatt, S. D., and Yuan, T.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
In this White Paper, we present recommendations for the scientific community and funding agencies to foster the infrastructure for a collaborative multi-messenger and time-domain astronomy (MMA/TDA) ecosystem. MMA/TDA is poised for breakthrough discoveries in the coming decade. In much the same way that expanding beyond the optical bandpass revealed entirely new and unexpected discoveries, cosmic messengers beyond light (i.e., gravitational waves, neutrinos, and cosmic rays) open entirely new windows to answer some of the most fundamental questions in (astro)physics: heavy element synthesis, equation of state of dense matter, particle acceleration, etc. This field was prioritized as a frontier scientific pursuit in the 2020 Decadal Survey on Astronomy and Astrophysics via its "New Windows on the Dynamic Universe" theme. MMA/TDA science presents technical challenges distinct from those experienced in other disciplines. Successful observations require coordination across myriad boundaries -- different cosmic messengers, ground vs. space, international borders, etc. -- all for sources that may not be well localized, and whose brightness may be changing rapidly with time. Add that all of this work is undertaken by real human beings, with distinct backgrounds, experiences, cultures, and expectations, that often conflict. To address these challenges and help MMA/TDA realize its full scientific potential in the coming decade (and beyond), the second in a series of community workshops sponsored by the U.S. National Science Foundation (NSF) and NASA titled "Windows on the Universe: Establishing the Infrastructure for a Collaborative Multi-Messenger Ecosystem" was held on October 16-18, 2023 in Tucson, AZ. Here we present the primary recommendations from this workshop focused on three key topics -- hardware, software, and people and policy. [abridged], Comment: Workshop white paper
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- 2024
16. Global changes in extreme tropical cyclone wave heights under projected future climate conditions
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Grossmann-Matheson, Guisela, Young, Ian R., Meucci, Alberto, and Alves, Jose-Henrique
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- 2024
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17. Barriers and facilitators to medication-assisted treatment for cocaine use disorder among men who have sex with men: a qualitative study
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Hsiang, Elaine, Patel, Kishan, Wilson, Erin C., Dunham, Alexandrea, Ikeda, Janet, Matheson, Tim, and Santos, Glenn-Milo
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- 2024
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18. Correction: Using digital technology to reduce drug-related harms: a targeted service users’ perspective of the Digital Lifelines Scotland programme
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Strachan, Graeme, Daneshvar, Hadi, Carver, Hannah, Greenhalgh, Jessica, and Matheson, Catriona
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- 2024
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19. Using digital technology to reduce drug-related harms: a targeted service users’ perspective of the Digital Lifelines Scotland programme
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Strachan, Graeme, Daneshvar, Hadi, Carver, Hannah, Greenhalgh, Jessica, and Matheson, Catriona
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- 2024
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20. Fluorescence lifetime imaging with distance and ranging using a miniaturised SPAD system
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Matheson, Andrew B., Hopkinson, Charlotte, Tanner, Michael G., and Henderson, Robert K.
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- 2024
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21. Characterization of peer support services for substance use disorders in 11 US emergency departments in 2020: findings from a NIDA clinical trials network site selection process
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Jennings, Lindsey K, Lander, Laura, Lawdahl, Tricia, McClure, Erin A., Moreland, Angela, McCauley, Jenna L., Haynes, Louise, Matheson, Timothy, Jones, Richard, Robey, Thomas E., Kawasaki, Sarah, Moschella, Phillip, Raheemullah, Amer, Miller, Suzette, Gregovich, Gina, Waltman, Deborah, Brady, Kathleen T., and Barth, Kelly S.
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- 2024
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22. Addendum: A neural circuit for wind-guided olfactory navigation
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Matheson, Andrew M. M., Lanz, Aaron J., Medina, Ashley M., Licata, Al M., Currier, Timothy A., Syed, Mubarak H., and Nagel, Katherine I.
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- 2024
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23. Global tropical cyclone extreme wave height climatology
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Grossmann-Matheson, Guisela, Young, Ian R., Meucci, Alberto, and Alves, Jose-Henrique
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- 2024
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24. Processes of development related with the implementation of the Icelandic prevention model in a rural Canadian community
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Tanya Halsall, Kianna Mahmoud, Matt Drabenstott, Heather Orpana, Srividya N. Iyer, Alfgeir Kristjansson, and Kimberly Matheson
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Substance use prevention ,Youth ,Process evaluation ,COVID ,Health equity ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract The Icelandic Prevention Model (IPM) is a sequential 10-step community-driven collaborative intervention that is designed to support the prevention of substance use in youth by establishing healthy developmental contexts. The IPM has been implemented across Iceland for over 20 years and is now being implemented in other countries. Recognizing the need to explore how to adapt the IPM to new contexts and document the implementation of the model, this paper describes a process evaluation of the first three steps of the IPM within a Canadian rural community to capture experiences during the early development. Specifically, this study addresses the following research questions: (1) What are the processes of development and contextual features that influence the implementation of the IPM within Lanark County, Ontario? and (2) What adaptations are needed to successfully implement the IPM in Canada? Semi-structured interviews were conducted to examine experiences and lessons learned through the implementation of the model. Thematic analyses were completed using QSR NVivo. A deductive and inductive approach was applied, whereby some interview guide questions were derived from the IPM implementation steps and others were more exploratory, examining context and processes of development. Nine interviews were conducted with key partners who were leading the implementation of the IPM. Themes highlighting cultural factors that influence implementation, processes of development related to community engagement, and themes relating to youth participation, fidelity issues, fundraising, health equity and challenges related to the COVID-19 pandemic were identified. This paper contributes new scientific knowledge related to implementation processes within upstream prevention of substance use and practical information that is useful for communities interested in implementing the IPM.
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- 2025
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25. Establishing the effect of computed tomography reconstruction kernels on the measure of bone mineral density in opportunistic osteoporosis screening
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Bryn E. Matheson and Steven K. Boyd
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Bone mineral density ,Opportunistic computed tomography ,Reconstruction kernels ,Medicine ,Science - Abstract
Abstract Opportunistic computed tomography (CT) scans, which can assess relevant bones of interest, offer a potential solution for identifying osteoporotic individuals. However, it has been well documented that image protocol parameters, such as reconstruction kernel, impact the quantitative analysis of volumetric bone mineral density (vBMD) from CT scans. The purpose of this study was to investigate the impact that CT reconstruction kernels have on quantitative results for vBMD from clinical CT scans using phantom and internal calibration. 45 clinical CT scans were reconstructed using the standard kernel and seven alternative kernels: soft, chest, detail, edge, bone, bone plus and lung [GE HealthCare]. Two methods of image calibration, internal and phantom, were used to calibrate the scans. The total hip and fourth lumbar vertebra (L4) were extracted from the scans via deep learning segmentation. Integral vBMD was calculated based on both calibration techniques from CT scans reconstructed with the eight kernels. Linear regression and Bland-Altman analyses were used to determine the coefficient of determination $${R}^2$$ and to quantify the agreement between the different kernels. Differences between the reconstruction kernels were determined using paired t tests, and mean differences from the standard were computed. Using internal calibration, the smoothest kernel (soft) yielded a mean difference of −0.95 mg/cc (−0.33%) compared to the reference standard at the L4 vertebra and 2.07 mg/cc (0.51%) at the left femur. The sharpest kernel (lung) yielded a mean difference of 25.36 mg/cc (9.63%) at the L4 vertebra and −25.10 mg/cc (−5.98%) at the left femur. Alternatively, using phantom calibration soft yielded higher mean differences than internal calibration at both locations, with mean differences of 1.21 mg/cc (0.42%) at the L4 vertebra and 2.53 mg/cc (0.65%) at the left femur. The most error-prone results stemmed from the use of the lung kernel, as this kernel displayed a mean difference of −21.90 mg/cc (−7.38%) and −17.24 mg/cc (−4.34%) at the L4 vertebra and femur, respectively. These results indicate when performing opportunistic CT analysis, errors due to interchanging smoothing kernels soft, chest and detail are negligible, but that interchanging between sharpening kernels (lung, bone, bone plus, edge) results in large errors that can significantly impact vBMD measures for osteoporosis screening and diagnosis.
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- 2025
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26. Applying Normalisation Process Theory to a peer-delivered complex health intervention for people experiencing homelessness and problem substance use
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Rebecca Foster, Hannah Carver, Catriona Matheson, Bernie Pauly, Jason Wallace, Graeme MacLennan, John Budd, and Tessa Parkes
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Medicine - Abstract
Abstract Background The Supporting Harm Reduction through Peer Support (SHARPS) study involved designing and implementing a peer-delivered, harm reduction intervention for people experiencing homelessness and problem substance use. Normalisation Process Theory (NPT) provided a framework for the study. Methods Four Peer Navigators (individuals with personal experience of problem substance use and/or homelessness) were recruited and hosted in six third sector (not-for-profit) homelessness services in Scotland and England (United Kingdom). Each worked with participants to provide practical and emotional support, with the aim of reducing harms, and improving well-being, social functioning and quality of life. NPT guided the development of the intervention and, the process evaluation, which assessed the acceptability and feasibility of the intervention for this cohort who experience distinct, and often unmet, health challenges. While mixed-methods data collection was undertaken, this paper draws only on the qualitative data. Results The study found that, overall, the intervention is feasible, and acceptable to, the intervention participants, the Peer Navigators and staff in host settings. Some challenges were encountered but these were outweighed by benefits. NPT is particularly useful in encouraging our team to focus on the relationship between different aspects of the intervention and context(s) and identify ways of maximising ‘fit’. Conclusions To our knowledge, this is the first application of NPT to this cohort, and specifically by non-clinicians (peers) in non-healthcare settings (homelessness services). Our application of NPT helped us to identify ways in which the intervention could be enhanced, with the key aim of improving the health/well-being of this underserved group.
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- 2025
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27. Norm-Referenced Effects of a Campus-Based Therapeutic Mentoring Program
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Gary Rempe, Michelle N. Saltis, David W. Matheson, and Sydney Cople
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The purpose of this study was to explore potential effects of a 12-week therapeutic mentoring program targeting social, emotional, and behavioral concerns in 52 children and adolescents between 11 and 17 years of age. Self-reported scores on a norm-referenced behavioral questionnaire were tracked across the span of a mentoring program, and then analyzed using multilevel modeling. Results showed that participant scores changed in a healthy direction across all domains measured (i.e., conduct, negative affect, cognitive/attention, and academic functioning). Predictors in the multilevel model included caregiver-reported sex assigned at birth, the semester that the intervention took place, and whether a participant had repeated the program. Findings lend further support to research-based mentoring programs as effective community interventions to address behavioral, emotional, social, and academic concerns in youth.
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- 2023
28. Psychoanalysis and the New Rhetoric by Daniel Adleman and Chris Vanderwees (review)
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Matheson, Calum
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- 2024
29. Multi-view Hybrid Graph Convolutional Network for Volume-to-mesh Reconstruction in Cardiovascular MRI
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Gaggion, Nicolás, Matheson, Benjamin A., Xia, Yan, Bonazzola, Rodrigo, Ravikumar, Nishant, Taylor, Zeike A., Milone, Diego H., Frangi, Alejandro F., and Ferrante, Enzo
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Cardiovascular magnetic resonance imaging is emerging as a crucial tool to examine cardiac morphology and function. Essential to this endeavour are anatomical 3D surface and volumetric meshes derived from CMR images, which facilitate computational anatomy studies, biomarker discovery, and in-silico simulations. However, conventional surface mesh generation methods, such as active shape models and multi-atlas segmentation, are highly time-consuming and require complex processing pipelines to generate simulation-ready 3D meshes. In response, we introduce HybridVNet, a novel architecture for direct image-to-mesh extraction seamlessly integrating standard convolutional neural networks with graph convolutions, which we prove can efficiently handle surface and volumetric meshes by encoding them as graph structures. To further enhance accuracy, we propose a multiview HybridVNet architecture which processes both long axis and short axis CMR, showing that it can increase the performance of cardiac MR mesh generation. Our model combines traditional convolutional networks with variational graph generative models, deep supervision and mesh-specific regularisation. Experiments on a comprehensive dataset from the UK Biobank confirm the potential of HybridVNet to significantly advance cardiac imaging and computational cardiology by efficiently generating high-fidelity and simulation ready meshes from CMR images.
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- 2023
30. SpectAcLE: An Improved Method for Modeling Light Echo Spectra
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Partoush, Roee, Rest, Armin, Jencson, Jacob E., Poznanski, Dovi, Foley, Ryan J., Kilpatrick, Charles D., Andrews, Jennifer E., Angulo, Rodrigo, Badenes, Carles, Bianco, Federica B., Filippenko, Alexei V., Ridden-Harper, Ryan, Li, Xiaolong, Margheim, Steve, Matheson, Thomas, Olsen, Knut A. G., Siebert, Matthew R., Smith, Nathan, Welch, Douglas L., and Zenteno, A.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Light echoes give us a unique perspective on the nature of supernovae and non-terminal stellar explosions. Spectroscopy of light echoes can reveal details on the kinematics of the ejecta, probe asymmetry, and reveal details on its interaction with circumstellar matter, thus expanding our understanding of these transient events. However, the spectral features arise from a complex interplay between the source photons, the reflecting dust geometry, and the instrumental setup and observing conditions. In this work we present an improved method for modeling these effects in light echo spectra, one that relaxes the simplifying assumption of a light curve weighted sum, and instead estimates the true relative contribution of each phase. We discuss our logic, the gains we obtain over light echo analysis method(s) used in the past, and prospects for further improvements. Lastly, we show how the new method improves our analysis of echoes from Tycho's supernova (SN 1572) as an example.
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- 2023
31. Family-based treatment (FBT) for loss of control (LOC) eating in youth: Current knowledge and future directions.
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Matheson, Brittany, Bohon, Cara, Le Grange, Daniel, and Lock, James
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Adolescent ,Child ,Female ,Humans ,Male ,Anorexia Nervosa ,Bulimia Nervosa ,Hispanic or Latino ,Treatment Outcome ,White ,Family Therapy - Abstract
Loss of control (LOC) eating in youth is a common disordered eating behavior and associated with negative health and psychological sequalae. Family-based treatment (FBT) is an efficacious treatment for adolescent anorexia nervosa and bulimia nervosa (BN) but has not been formally evaluated for adolescents with LOC eating. This study is a secondary data analysis from a randomized controlled clinical trial (NCT00879151) testing FBT for 12-18-year-olds with BN. Data were reanalyzed to examine outcomes for LOC eating episodes, regardless of episode size. Abstinence rates, defined as zero LOC eating episodes (objective or subjective binge episodes) in the previous month, were calculated at the end-of-treatment (EOT), 6-month, and 12-month follow-up time points. Among 51 adolescent participants (M + SD: 15.94 + 1.53 y; 92% female; 23.5% Hispanic; 76.5% Caucasian), FBT significantly reduced LOC eating episodes, with 49% achieving LOC eating abstinence at EOT. At 6-month follow-up, 41% achieved LOC eating abstinence. Of those providing 12-month follow-up data, 73% achieved abstinence. This preliminary exploration suggests that FBT may be effective for youth with LOC eating, regardless of episode size. Additional research is needed to replicate these findings and extend treatments with developmental adaptations for younger children with LOC eating.
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- 2024
32. The Pink Wave: Women Running for Office After Trump
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Parsons, William W., author, Matheson, Regina M., author, Parsons, William W., and Matheson, Regina M.
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- 2023
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33. The Tihei Rangatahi Research Programme: Tailoring a community-based youth empowerment programme for Rangatahi Maori
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Tupai-Firestone, Ridvan, Davies, Cheryl, Davies, Renee, Fleming, Terry, Te Morenga, Lisa, Kingi, Te Kani, O’Connell, Angelique, Matheson, Anna, Brown, Blakely, and Ellision-Loschmann, Lis
- Published
- 2024
34. Archaeological evidence of an ethnographically documented Australian Aboriginal ritual dated to the last ice age
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David, Bruno, Mullett, Russell, Wright, Nathan, Stephenson, Birgitta, Ash, Jeremy, Fresløv, Joanna, Delannoy, Jean-Jacques, McDowell, Matthew C., Mialanes, Jerome, Petchey, Fiona, Arnold, Lee J., Rogers, Ashleigh J., Crouch, Joe, Green, Helen, Urwin, Chris, and Matheson, Carney D.
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- 2024
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35. Intentional Imperfection Program: A pilot randomised controlled trial to help university students manage perfectionism
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Visvalingam, Shanara, Matheson, Angelica C., Magson, Natasha R., and Norberg, Melissa M.
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- 2024
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36. Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism
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Jekhmane, Shehrazade, Derks, Maik G. N., Maity, Sourav, Slingerland, Cornelis J., Tehrani, Kamaleddin H. M. E., Medeiros-Silva, João, Charitou, Vicky, Ammerlaan, Danique, Fetz, Céline, Consoli, Naomi A., Cochrane, Rachel V. K., Matheson, Eilidh J., van der Weijde, Mick, Elenbaas, Barend O. W., Lavore, Francesca, Cox, Ruud, Lorent, Joseph H., Baldus, Marc, Künzler, Markus, Lelli, Moreno, Cochrane, Stephen A., Martin, Nathaniel I., Roos, Wouter H., Breukink, Eefjan, and Weingarth, Markus
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- 2024
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37. A “food insecurity poverty line” to replace the official threshold in Canadian rural and urban settings? A single-person household perspective
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Ross, Kent, Liu, Tong, Guo, Xiaolin, Matheson, Jesse, and Dutton, Daniel J.
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- 2024
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38. Brief Report: The Rise of Online Betting in Ontario
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Turner, Nigel E., Sinclair, Lindsay, and Matheson, Flora I.
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- 2024
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39. The SN 2023ixf Progenitor in M101: II. Properties
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Van Dyk, Schuyler D., Srinivasan, Sundar, Andrews, Jennifer E., Soraisam, Monika, Szalai, Tamas, Howell, Steve B., Isaacson, Howard, Matheson, Thomas, Petigura, Erik, Scicluna, Peter, Stephens, Andrew W., Van Zandt, Judah, Zheng, WeiKang, Chun, Sang-Hyun, and Filippenko, Alexei V.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
We follow our first paper with an analysis of the ensemble of the extensive pre-explosion ground- and space-based infrared observations of the red supergiant (RSG) progenitor candidate for the nearby core-collapse supernova SN 2023ixf in Messier 101, together with optical data prior to explosion obtained with the Hubble Space Telescope (HST). We have confirmed the association of the progenitor candidate with the SN, as well as constrained the metallicity at the SN site, based on SN observations with instruments at Gemini-North. The internal host extinction to the SN has also been confirmed from a high-resolution Keck spectrum. We fit the observed spectral energy distribution (SED) for the star, accounting for its intrinsic variability, with dust radiative-transfer modeling, which assume a silicate-rich dust shell ahead of the underlying stellar photosphere. The star is heavily dust-obscured, likely the dustiest progenitor candidate yet encountered. We found median estimates of the star's effective temperature and luminosity of 2770 K and 9.0e4 L_Sun, with 68% credible intervals of 2340--3150 K and (7.5--10.9)e4 L_sun. The candidate may have a Galactic RSG analog, IRC -10414, with a strikingly similar SED and luminosity. Via comparison with single-star evolutionary models we have constrained the initial mass of the progenitor candidate from 12 M_sun to as high as 14 M_sun. We have had available to us an extraordinary view of the SN 2023ixf progenitor candidate, which should be further followed up in future years with HST and the James Webb Space Telescope., Comment: 40 pages, substantive modifications relative to the previous, although the overall conclusions remain the same; to appear in AAS Journals
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- 2023
40. The SN 2023ixf Progenitor in M101: I. Infrared Variability
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Soraisam, Monika D., Szalai, Tamás, Van Dyk, Schuyler D., Andrews, Jennifer E., Srinivasan, Sundar, Chun, Sang-Hyun, Matheson, Thomas, Scicluna, Peter, and Vasquez-Torres, Diego A.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Observational evidence points to a red supergiant (RSG) progenitor for SN 2023ixf. The progenitor candidate has been detected in archival images at wavelengths (>0.6 micron) where RSGs typically emit profusely. This object is distinctly variable in the infrared (IR). We characterize the variability using pre-explosion mid-IR (3.6 and 4.5 micron) Spitzer and ground-based near-IR (JHKs) archival data jointly covering 19 yr. The IR light curves exhibit significant variability with RMS amplitudes in the range of 0.2-0.4 mag, increasing with decreasing wavelength. From a robust period analysis of the more densely sampled Spitzer data, we measure a period of 1091+/-71 days. We demonstrate using Gaussian Process modeling that this periodicity is also present in the near-IR light curves, thus indicating a common physical origin, which is likely pulsational instability. We use a period-luminosity relation for RSGs to derive a value of M_K=-11.58+/-0.31 mag. Assuming a late M spectral type, this corresponds to log(L/L_sun)=5.27+/-0.12 at T_eff=3200 K and to log(L/L_sun)=5.37+/-0.12 at T_eff=3500 K. This gives an independent estimate of the progenitor's luminosity, unaffected by uncertainties in extinction and distance. Assuming the progenitor candidate underwent enhanced dust-driven mass-loss during the time of these archival observations, and using an empirical period-luminosity-based mass-loss prescription, we obtain a mass-loss rate of around (2-4)x10^-4 M_sun/yr. Comparing the above luminosity with stellar evolution models, we infer an initial mass for the progenitor candidate of 20+/-4 M_sun, making this one of the most massive progenitors for a Type II SN detected to-date., Comment: 20 pages, 2 tables, accepted to ApJ
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- 2023
41. Emotional Imperialism
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Archer, Alfred and Matheson, Benjamin
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- 2024
42. All-Sky Faint DA White Dwarf Spectrophotometric Standards for Astrophysical Observatories: The Complete Sample
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Axelrod, Tim, Saha, Abhijit, Matheson, Thomas, Olszewski, Edward W., Bohlin, Ralph C., Calamida, Annalisa, Claver, Jenna, Deustua, Susana, Holberg, Jay B., Hubeny, Ivan, Mackenty, John W., Malanchev, Konstantin, Narayan, Gautham, Points, Sean, Rest, Armin, Sabbi, Elena, and Stubbs, Christopher W.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Hot DA white dwarfs have fully radiative pure hydrogen atmospheres that are the least complicated to model. Pulsationally stable, they are fully characterized by their effective temperature Teff, and surface gravity log g, which can be deduced from their optical spectra and used in model atmospheres to predict their spectral energy distribution (SED). Based on this, three bright DAWDs have defined the spectrophotometric flux scale of the CALSPEC system of HST. In this paper we add 32 new fainter (16.5 < V < 19.5) DAWDs spread over the whole sky and within the dynamic range of large telescopes. Using ground based spectra and panchromatic photometry with HST/WFC3, a new hierarchical analysis process demonstrates consistency between model and observed fluxes above the terrestrial atmosphere to < 0.004 mag rms from 2700 {\AA} to 7750 {\AA} and to 0.008 mag rms at 1.6{\mu}m for the total set of 35 DAWDs. These DAWDs are thus established as spectrophotometric standards with unprecedented accuracy from the near ultraviolet to the near-infrared, suitable for both ground and space based observatories. They are embedded in existing surveys like SDSS, PanSTARRS and GAIA, and will be naturally included in the LSST survey by Rubin Observatory. With additional data and analysis to extend the validity of their SEDs further into the IR, these spectrophotometric standard stars could be used for JWST, as well as for the Roman and Euclid observatories., Comment: Accepted for publication in Astrophysical Journal. Corrected error in Table 10 and associated Fig 7 in which RP and BP values for the 3 CALSPEC standards had been transposed
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- 2023
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43. A von Mises-Fisher Distribution for the Orbital Poles of the Plutinos
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Matheson, Ian C., Malhotra, Renu, and Keane, James T.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Small solar system bodies have widely dispersed orbital poles, posing challenges to dynamical models of solar system origin and evolution. To characterize the orbit pole distribution of dynamical groups of small bodies it helps to have a functional form for a model of the distribution function. Previous studies have used the small-inclination approximation and adopted variations of the normal distribution to model orbital inclination dispersions. Because the orbital pole is a directional variable, its distribution can be more appropriately modeled with directional statistics. We describe the von Mises-Fisher (vMF) distribution on the surface of the unit sphere for application to small bodies' orbital poles. We apply it to the orbit pole distribution of the observed Plutinos. We find a mean pole located at inclination of 3.57 degrees and a longitude of ascending node of 124.38 degrees (in the J2000 reference frame), with a 99.7 per cent confidence cone of half-angle 1.68 degrees. We also estimate a debiased mean pole located 4.6 degrees away, at an inclination of 2.26 degrees and a longitude of ascending node of 292.69 degrees, of similar-size confidence cone. The vMF concentration parameter of Plutino inclinations (relative to either mean pole estimate) is 31.6. This resembles a Rayleigh distribution function with a width parameter of 10.2 degrees. Unlike previous models, the vMF model naturally accommodates all physical inclinations (and no others), whereas Rayleigh or Gaussian models must be truncated to the physical inclination range 0-180 degrees. Further work is needed to produce a theory for the mean pole of the Plutinos against which to compare the observational results., Comment: 10 pages, 7 figures. Accepted for Monthly Notices of the Royal Astronomical Society (MNRAS) in April 2023
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- 2023
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44. A Measurement of the Kuiper Belt's Mean Plane From Objects Classified By Machine Learning
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Matheson, Ian C. and Malhotra, Renu
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Astrophysics - Earth and Planetary Astrophysics ,Computer Science - Machine Learning - Abstract
Mean plane measurements of the Kuiper Belt from observational data are of interest for their potential to test dynamical models of the solar system. Recent measurements have yielded inconsistent results. Here we report a measurement of the Kuiper Belt's mean plane with a sample size more than twice as large as in previous measurements. The sample of interest is the non-resonant Kuiper belt objects, which we identify by using machine learning on the observed Kuiper Belt population whose orbits are well-determined. We estimate the measurement error with a Monte Carlo procedure. We find that the overall mean plane of the non-resonant Kuiper Belt (semimajor axis range 35-150 au) and also that of the classical Kuiper Belt (semimajor axis range 42-48 au) are both close to (within about 0.7 degrees) but distinguishable from the invariable plane of the solar system to greater than 99.7% confidence. When binning the sample into smaller semimajor axis bins, we find the measured mean plane mostly consistent with both the invariable plane and the theoretically expected Laplace surface forced by the known planets. Statistically significant discrepancies are found only in the semimajor axis ranges 40.3-42 au and 45-50 au; these ranges are in proximity to a secular resonance and Neptune's 2:1 mean motion resonance where the theory for the Laplace surface is likely to be inaccurate. These results do not support a previously reported anomalous warp at semimajor axes above 50 au., Comment: 15 pages, 4 figures. Accepted for The Astronomical Journal
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- 2023
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45. Early-Time Ultraviolet and Optical Hubble Space Telescope Spectroscopy of the Type II Supernova 2022wsp
- Author
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Vasylyev, Sergiy S., Vogl, Christian, Yang, Yi, Filippenko, Alexei V., Brink, Thomas G., Brown, Peter J., Matheson, Thomas, Gal-Yam, Avishay, Mazzali, Paolo A., de Jaeger, Thomas, Patra, Kishore C., and Stewart, Gabrielle E.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report early-time ultraviolet (UV) and optical spectroscopy of the young, nearby Type II supernova (SN) 2022wsp obtained by the Hubble Space Telescope (HST)/STIS at about 10 and 20 days after the explosion. The SN 2022wsp UV spectra are compared to those of other well-observed Type II/IIP SNe, including the recently studied Type IIP SN 2021yja. Both SNe exhibit rapid cooling and similar evolution during early phases, indicating a common behavior among SNe II. Radiative-transfer modeling of the spectra of SN 2022wsp with the TARDIS code indicates a steep radial density profile in the outer layer of the ejecta, a supersolar metallicity, and a relatively high total extinction of E(B-V) = 0.35 mag. The early-time evolution of the photospheric velocity and temperature derived from the modeling agree with the behavior observed from other previously studied cases. The strong suppression of hydrogen Balmer lines in the spectra suggests interaction with a pre-existing circumstellar environment could be occurring at early times. In the SN 2022wsp spectra, the absorption component of the Mg II P Cygni profile displays a double-trough feature on day +10 that disappears by day +20. The shape is well reproduced by the model without fine-tuning the parameters, suggesting that the secondary blueward dip is a metal transition that originates in the SN ejecta., Comment: Submitted to ApJ Letters on 4/11/2023
- Published
- 2023
46. Police Funding and Crime Rates in 20 of Canada’s Largest Municipalities : A Longitudinal Study
- Author
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SEABROOK, MÉLANIE S.S., LUSCOMBE, ALEX, BALIAN, NICOLE, LOFTERS, AISHA, MATHESON, FLORA I., O’NEILL, BRADEN G., OWUSU-BEMPAH, AKWASI, PERSAUD, NAVINDRA, and PINTO, ANDREW D.
- Published
- 2023
47. Protocol and Statistical Analysis Plan for a Comparative Interrupted Time Series Evaluation of the Impact of Deemed Consent for Organ Donation Legislative Reform in Nova Scotia, Canada
- Author
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Matthew J. Weiss, MD, Kristina Krmpotic, MD, Stephen Beed, MD, Sonny Dhanani, MD, Jade Dirk, BSc, David Hartell, MA, Cynthia Isenor, RN, MScN, Nick Lahaie, Scott T. Leatherdale, PhD, Kara Matheson, MSc, Karthik Tennankore, MD, SM, Gail Tomblin-Murphy, PhD, BN, MN, Amanda Vinson, MD, Hans Vorster, BASc, and Caroline King, PhD
- Subjects
Surgery ,RD1-811 - Abstract
The Canadian province of Nova Scotia recently became the first North American jurisdiction to implement deemed consent for deceased organ donation as part of a comprehensive legislative reform of their donation and transplantation system. This study will examine the performance metrics and effectiveness of this policy in comparison with other Canadian provinces via a natural experiment evaluation. We will use a cross-sectional controlled interrupted time series quasi-experimental design. Our primary outcome will be consent for deceased donation as confirmed at the time of eligibility (prior registered intent to donate will be noted but not be considered positive unless affirmed at the time of eligibility). Secondary outcomes will include identification and referral of patients who are potential donors, rates of family override of previously registered intent to donate, and donation and transplantation rates per million population. Data will be collected from potential donor audits in Nova Scotia and 3 control provinces (provinces in Canada without deemed consent policies). Study outcomes will be compared in Nova Scotia relative to control provinces in the 3 y before and 3 y after the implementation of legislative reform. These provinces were selected as having systems resembling those of Nova Scotia but without deemed consent.Using controlled interrupted time series methodology compared with other Canadian provinces with otherwise similar systems, we aim to isolate the impact of the deemed consent aspect of legislative reform in Nova Scotia using a robust natural experiment evaluation design as much as possible. Careful selection of outcome measures will allow donation and transplantation stakeholders to properly evaluate if similar reforms should be considered in their jurisdictions.
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- 2024
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48. Interlaboratory comparison of a multiplex immunoassay that measures human serum IgG antibodies against six-group B streptococcus polysaccharides
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Kirsty Le Doare, Michelle A. Gaylord, Annaliesa S. Anderson, Nick Andrews, Carol J. Baker, Shanna Bolcen, Arif Felek, Peter C. Giardina, Christopher D. Grube, Tom Hall, Bassam Hallis, Alane Izu, Shabir A. Madhi, Pete Maniatis, Mary Matheson, Fatme Mawas, Andrew McKeen, Julia Rhodes, Bailey Alston, Palak Patel, Stephanie Schrag, Raphael Simon, Charles Y. Tan, Stephen Taylor, Gaurav Kwatra, and Andrew Gorringe
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Group B streptococcus ,maternal ,neonatal ,correlate of protection ,vaccines ,Immunologic diseases. Allergy ,RC581-607 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
ABSTRACTMeasurement of IgG antibodies against group B streptococcus (GBS) capsular polysaccharide (CPS) by use of a standardized and internationally accepted multiplex immunoassay is important for the evaluation of candidate maternal GBS vaccines in order to compare results across studies. A standardized assay is also required if serocorrelates of protection against invasive GBS disease are to be established in infant sera for the six predominant GBS serotypes since it would permit the comparison of results across the six serotypes. We undertook an interlaboratory study across five laboratories that used standardized assay reagents and protocols with a panel of 44 human sera to measure IgG antibodies against GBS CPS serotypes Ia, Ib, II, III, IV, and V. The within-laboratory intermediate precision, which included factors like the lot of coated beads, laboratory analyst, and day, was generally below 20% relative standard deviation (RSD) for all six serotypes, across all five laboratories. The cross-laboratory reproducibility was
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- 2024
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49. Chest CT Airway and Vascular Measurements in Females with COPD or Long-COVID
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Harkiran K. Kooner, Paulina V. Wyszkiewicz, Alexander M. Matheson, Marrissa J. McIntosh, Mohamed Abdelrazek, Inderdeep Dhaliwal, J. Michael Nicholson, Miranda Kirby, Sarah Svenningsen, and Grace Parraga
- Subjects
CT ,COVID-19 ,long-COVID ,coronavirus disease ,COPD ,pulmonary airways ,Diseases of the respiratory system ,RC705-779 - Abstract
Chest CT provides a way to quantify pulmonary airway and vascular tree measurements. In patients with COPD, CT airway measurement differences in females are concomitant with worse quality-of-life and other outcomes. CT total airway count (TAC), airway lumen area (LA), and wall thickness (WT) also differ in females with long-COVID. Our objective was to evaluate CT airway and pulmonary vascular and quality-of-life measurements in females with COPD as compared to ex-smokers and patients with long-COVID. Chest CT was acquired 3-months post-COVID-19 infection in females with long-COVID for comparison with the same inspiratory CT in female ex-smokers and COPD patients. TAC, LA, WT, and pulmonary vascular measurements were quantified. Linear regression models were adjusted for confounders including age, height, body-mass-index, lung volume, pack-years and asthma diagnosis. Twenty-one females (53 ± 14 years) with long-COVID, 17 female ex-smokers (69 ± 9 years) and 13 female COPD (67 ± 6 years) patients were evaluated. In the absence of differences in quality-of-life scores, females with long-COVID reported significantly different LA (p = 0.006) compared to ex-smokers but not COPD (p = 0.7); WT% was also different compared to COPD (p = 0.009) but not ex-smokers (p = 0.5). In addition, there was significantly greater pulmonary small vessel volume (BV5) in long-COVID as compared to female ex-smokers (p = 0.045) and COPD (p = 0.003) patients and different large (BV10) vessel volume as compared to COPD (p = 0.03). In females with long-COVID and highly abnormal quality-of-life scores, there was CT evidence of airway remodelling, similar to ex-smokers and patients with COPD, but there was no evidence of pulmonary vascular remodelling.Clinical Trial Registration: www.clinicaltrials.gov NCT05014516 and NCT02279329
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- 2024
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50. Quick, Effective Screening Tasks Identify Children With Medical Conditions or Disabilities Needing Physical Literacy Support.
- Author
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Longmuir, Patricia E., Chubbs Payne, Adam, Beshara, Natalie, Brandão, Leonardo R., Wright, F. Virginia, Pohl, Daniela, Katz, Sherri Lynne, McCormick, Anna, De Laat, Denise, Klaassen, Robert J., Johnston, Donna L., Lougheed, Jane, Roth, Johannes, McMillan, Hugh J., Venkateswaran, Sunita, Sell, Erick, Doja, Asif, Boafo, Addo, Macartney, Gail, and Matheson, Katherine
- Subjects
HEALTH literacy ,CROSS-sectional method ,INTELLECT ,CHILDREN with disabilities ,EXERCISE ,RESEARCH funding ,QUESTIONNAIRES ,SCIENTIFIC observation ,SCREEN time ,CONFIDENCE ,DESCRIPTIVE statistics ,MOTIVATION (Psychology) ,STATISTICAL reliability ,MEDICAL screening ,HEALTH promotion ,DELPHI method ,SENSITIVITY & specificity (Statistics) ,PHYSICAL activity - Abstract
Purpose: This study evaluated screening tasks able to identify children with medical conditions or disabilities who may benefit from physical literacy. Method: Children completed ≤20 screening tasks during their clinic visit and then the Canadian Assessment of Physical Literacy (2nd edition) at a separate visit. Total Canadian Assessment of Physical Literacy scores <30th percentile were categorized as potentially needing physical literacy support. Receiver operator characteristic curves identified assessment cut points with 80% sensitivity and 40% specificity relative to total physical literacy scores. Results: 223 children (97 girls; 10.1 [2.6] y) participated. Physical activity adequacy, predilection, and physical competence achieved ≥80% sensitivity and ≥40% specificity in both data sets. Adequacy ≤ 6.5 had 86% to 100% sensitivity and 48% to 49% specificity. Daily screen time >4.9 hours combined with Adequacy ≤6.15 had 88% to 10% sensitivity and 53% to 56% specificity. Conclusions: Activity adequacy, alone or with screen time, most effectively identified children likely to benefit from physical literacy support. Adequacy and screen time questionnaires are suitable for clinical use. Similar results regardless of diagnosis suggest physical competence deficits are not primary determinants of active lifestyles. Research to enhance screening specificity is required. [ABSTRACT FROM AUTHOR]
- Published
- 2025
- Full Text
- View/download PDF
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