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3. Accuracy of diagnostic tests for perilymphatic fistula: protocol for a systematic review.

Author

Situkho, Maksym, Ikezono, Tetsuo, Myhrum, Marte, Rødvik, Arne Kirkhorn, Maeda, Yukihide, Matsuda, Han, Sawada, Masafumi, and Jablonski, Greg Eigner

Subjects
INNER ear diseases, MIDDLE ear, INNER ear, DIAGNOSIS methods, DATA extraction
Abstract

Perilymphatic fistula (PLF) is a challenging inner ear condition, characterized by the abnormal connection between inner and middle ear and subsequent leakage of inner ear liquid (perilymph) into the middle ear. Early surgical intervention for PLF might lead to favorable audiological and vestibular outcomes. The conventional reference standard of PLF detection is the intraoperative visualization of perilymph leakage during explorative tympanotomy or endoscopic inspection; the specificity and sensitivity of this method is unknown. Systematic reviews assessing the accuracy of diagnostic tests for PLF are not available. Objective: To systematically review the literature for qualitative evidence exploring the diagnostic tests for the PLF diagnosis. The proposed systematic review will answer the following question: What is the accuracy of diagnostic tests in detecting perilymphatic fistula in humans? Methods: Eligibility criteria: original peer-reviewed articles regarding studies on humans of any age containing data with diagnostic test accuracy estimation (sensitivity and specificity) for PLF diagnosis or in which diagnostic test accuracy could be calculated based on data provided, without language, study design or study date limits. MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, Scopus, and Web of Science will be searched for eligible articles. Additional manual searches will be performed. Covidence software will be used for title and abstract screening, full text review and data extraction. The risk of bias assessment will be conducted using the Quality Assessment of Diagnostic Test Accuracy 2 (QUADAS-2) tool. If two or more high-quality articles evaluating the same diagnostic test will be identified, their findings will be quantitatively synthesized; if a quantitative synthesis is not feasible, the results will be described in a narrative summary. Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) framework will be used to evaluate evidence strength. Study funded by Oslo University Hospital. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Detailed clinical features and genotype–phenotype correlation in an OTOF-related hearing loss cohort in Japan

Author

Iwasa, Yoh-ichiro, Nishio, Shin-ya, Yoshimura, Hidekane, Sugaya, Akiko, Kataoka, Yuko, Maeda, Yukihide, Kanda, Yukihiko, Nagai, Kyoko, Naito, Yasushi, Yamazaki, Hiroshi, Ikezono, Tetsuo, Matsuda, Han, Nakai, Masako, Tona, Risa, Sakurai, Yuika, Motegi, Remi, Takeda, Hidehiko, Kobayashi, Marina, Kihara, Chiharu, Ishino, Takashi, Morita, Shin-ya, Iwasaki, Satoshi, Takahashi, Masahiro, Furutate, Sakiko, Oka, Shin-ichiro, Kubota, Toshinori, Arai, Yasuhiro, Kobayashi, Yumiko, Kikuchi, Daisuke, Shintani, Tomoko, Ogasawara, Noriko, Honkura, Yohei, Izumi, Shuji, Hyogo, Misako, Ninoyu, Yuzuru, Suematsu, Mayumi, Nakayama, Jun, Tsuchihashi, Nana, Okami, Mayuri, Sakata, Hideaki, Yoshihashi, Hiroshi, Kobayashi, Taisuke, Kumakawa, Kozo, Yoshida, Tadao, Esaki, Tomoko, and Usami, Shin-ichi

Published
2022
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5. Correction to: Detailed clinical features and genotype–phenotype correlation in an OTOF-related hearing loss cohort in Japan

Author

Iwasa, Yoh-ichiro, Nishio, Shin-ya, Yoshimura, Hidekane, Sugaya, Akiko, Kataoka, Yuko, Maeda, Yukihide, Kanda, Yukihiko, Nagai, Kyoko, Naito, Yasushi, Yamazaki, Hiroshi, Ikezono, Tetsuo, Matsuda, Han, Nakai, Masako, Tona, Risa, Sakurai, Yuika, Motegi, Remi, Takeda, Hidehiko, Kobayashi, Marina, Kihara, Chiharu, Ishino, Takashi, Morita, Shin-ya, Iwasaki, Satoshi, Takahashi, Masahiro, Furutate, Sakiko, Oka, Shin-ichiro, Kubota, Toshinori, Arai, Yasuhiro, Kobayashi, Yumiko, Kikuchi, Daisuke, Shintani, Tomoko, Ogasawara, Noriko, Honkura, Yohei, Izumi, Shuji, Hyogo, Misako, Ninoyu, Yuzuru, Suematsu, Mayumi, Nakayama, Jun, Tsuchihashi, Nana, Okami, Mayuri, Sakata, Hideaki, Yoshihashi, Hiroshi, Kobayashi, Taisuke, Kumakawa, Kozo, Yoshida, Tadao, Esaki, Tomoko, and Usami, Shin-ichi

Published
2022
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7. Prevalence of perilymphatic fistula in patients with sudden-onset sensorineural hearing loss as diagnosed by Cochlin-tomoprotein (CTP) biomarker detection: its association with age, hearing severity, and treatment outcomes

Author

Sasaki, Akira, primary, Ikezono, Tetsuo, additional, Matsuda, Han, additional, Araki, Ryuichiro, additional, Matsumura, Tomohiro, additional, Saitoh, Shiho, additional, Wasano, Koichiro, additional, and Matsubara, Atsushi, additional

Published
2023
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11. Correction to: Detailed clinical features and genotype–phenotype correlation in an OTOF-related hearing loss cohort in Japan

Author

Iwasa, Yoh-ichiro, primary, Nishio, Shin-ya, additional, Yoshimura, Hidekane, additional, Sugaya, Akiko, additional, Kataoka, Yuko, additional, Maeda, Yukihide, additional, Kanda, Yukihiko, additional, Nagai, Kyoko, additional, Naito, Yasushi, additional, Yamazaki, Hiroshi, additional, Ikezono, Tetsuo, additional, Matsuda, Han, additional, Nakai, Masako, additional, Tona, Risa, additional, Sakurai, Yuika, additional, Motegi, Remi, additional, Takeda, Hidehiko, additional, Kobayashi, Marina, additional, Kihara, Chiharu, additional, Ishino, Takashi, additional, Morita, Shin-ya, additional, Iwasaki, Satoshi, additional, Takahashi, Masahiro, additional, Furutate, Sakiko, additional, Oka, Shin-ichiro, additional, Kubota, Toshinori, additional, Arai, Yasuhiro, additional, Kobayashi, Yumiko, additional, Kikuchi, Daisuke, additional, Shintani, Tomoko, additional, Ogasawara, Noriko, additional, Honkura, Yohei, additional, Izumi, Shuji, additional, Hyogo, Misako, additional, Ninoyu, Yuzuru, additional, Suematsu, Mayumi, additional, Nakayama, Jun, additional, Tsuchihashi, Nana, additional, Okami, Mayuri, additional, Sakata, Hideaki, additional, Yoshihashi, Hiroshi, additional, Kobayashi, Taisuke, additional, Kumakawa, Kozo, additional, Yoshida, Tadao, additional, Esaki, Tomoko, additional, and Usami, Shin-ichi, additional

Published
2021
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12. Detailed clinical features and genotype–phenotype correlation in an OTOF-related hearing loss cohort in Japan

Author

Iwasa, Yoh-ichiro, primary, Nishio, Shin-ya, additional, Yoishimura, Hidekane, additional, Sugaya, Akiko, additional, Kataoka, Yuko, additional, Maeda, Yukihide, additional, Kanda, Yukihiko, additional, Nagai, Kyoko, additional, Naito, Yasushi, additional, Yamazaki, Hiroshi, additional, Ikezono, Tetsuo, additional, Matsuda, Han, additional, Nakai, Masako, additional, Tona, Risa, additional, Sakurai, Yuika, additional, Motegi, Remi, additional, Takeda, Hidehiko, additional, Kobayashi, Marina, additional, Kihara, Chiharu, additional, Ishino, Takashi, additional, Morita, Shin-ya, additional, Iwasaki, Satoshi, additional, Takahashi, Masahiro, additional, Furutate, Sakiko, additional, Oka, Shin-ichiro, additional, Kubota, Toshinori, additional, Arai, Yasuhiro, additional, Kobayashi, Yumiko, additional, Kikuchi, Daisuke, additional, Shintani, Tomoko, additional, Ogasawara, Noriko, additional, Honkura, Yohei, additional, Izumi, Shuji, additional, Hyogo, Misako, additional, Ninoyu, Yuzuru, additional, Suematsu, Mayumi, additional, Nakayama, Jun, additional, Tsuchihashi, Nana, additional, Okami, Mayuri, additional, Sakata, Hideaki, additional, Yoshihashi, Hiroshi, additional, Kobayashi, Taisuke, additional, Kumakawa, Kozo, additional, Yoshida, Tadao, additional, Esaki, Tomoko, additional, and Usami, Shin-ichi, additional

Published
2021
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16. The diagnostic performance of a novel ELISA for human CTP (Cochlin-tomoprotein) to detect perilymph leakage

Author

Ikezono, Tetsuo, primary, Matsumura, Tomohiro, additional, Matsuda, Han, additional, Shikaze, Satomi, additional, Saitoh, Shiho, additional, Shindo, Susumu, additional, Hasegawa, Setsuo, additional, Oh, Seung Ha, additional, Hagiwara, Yoshiaki, additional, Ogawa, Yasuo, additional, Ogawa, Hiroshi, additional, Sato, Hiroaki, additional, Tono, Tetsuya, additional, Araki, Ryuichiro, additional, Maeda, Yukihide, additional, Usami, Shin-ichi, additional, and Kase, Yasuhiro, additional

Published
2018
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17. Dural Arteriovenous Fistula Presenting with Pulsatile Tinnitus

Author

Numakura, Akane, primary, Kikkawa, Sayaka, additional, Kamijo, Atsushi, additional, Matsuda, Han, additional, Shindo, Susumu, additional, Ikezono, Tetsuo, additional, Kase, Yasuhiro, additional, Kohyama, Shinya, additional, Itoh, Akinori, additional, and Oosawa, Iichiro, additional

Published
2018
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18. A nationwide multicenter study of the Cochlin tomo-protein detection test: clinical characteristics of perilymphatic fistula cases

Author

Matsuda, Han, primary, Sakamoto, Kei, additional, Matsumura, Tomohiro, additional, Saito, Shiho, additional, Shindo, Susumu, additional, Fukushima, Kunihiro, additional, Nishio, Shin-ya, additional, Kitoh, Ryosuke, additional, Shibasaki, Osamu, additional, Ito, Akinori, additional, Araki, Ryuichiro, additional, Usami, Shin-ichi, additional, Suzuki, Mamoru, additional, Ogawa, Kaoru, additional, Hasegawa, Tomonori, additional, Hagiwara, Yoshiaki, additional, Kase, Yasuhiro, additional, and Ikezono, Tetsuo, additional

Published
2017
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27. Mutual evaluation of Caloric Test and video Head Impulse Test

Author

Shindo, Susumu, primary, Sugizaki, Kazuki, additional, Itoh, Akinori, additional, Shibasaki, Osamu, additional, Mizuno, Masahiro, additional, Matsuda, Han, additional, Inoue, Tomoe, additional, Numakura, Akane, additional, Kase, Yasuhiro, additional, and Ikezono, Tetsuo, additional

Published
2015
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32. Cochlin-tomoprotein (CTP) detection test identifies traumatic perilymphatic fistula due to penetrating middle ear injury

Author

Ikezono, Tetsuo, primary, Shindo, Susumu, additional, Sekine, Kuwon, additional, Shiiba, Kyoko, additional, Matsuda, Han, additional, Kusama, Kaoru, additional, Koizumi, Yasuo, additional, Sugizaki, Kazuki, additional, Sekiguchi, Satomi, additional, Kataoka, Ryohei, additional, Pawankar, Ruby, additional, Baba, Shunkichi, additional, Yagi, Toshiaki, additional, and Okubo, Kimihiro, additional

Published
2011
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34. Practicality of multilayer round window reinforcement in the surgical management of superior semicircular canal dehiscence syndrome: a case report of long-term follow-up.

Author

Sawada M, Matsuda H, Tanzawa Y, Sakamoto K, Kudo H, Nakashima M, and Ikezono T

Abstract

Several surgical techniques have been documented for approaching and repairing superior semicircular canal dehiscence syndrome (SCDS). These techniques encompass the trans-middle cranial fossa, transmastoid, endoscopic approaches, and round window reinforcement (RWR). RWR entails the placement of connective tissue with or without cartilage and around the round window niche, restricting the round window's movement to minimize the 3rd window effect and restore the bony labyrinth closer to its normal state. We employed the multilayer RWR technique, resulting in significant postoperative improvement and long-lasting effects for 3.7 years in 2 cases. Here, we present the clinical findings, surgical procedures, and the effectiveness of multilayer RWR. This technique can be the initial choice for surgical treatments of SCDS due to its high effectiveness, longer-lasting effect, and minimal risk of surgical complications., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Sawada, Matsuda, Tanzawa, Sakamoto, Kudo, Nakashima and Ikezono.)

Published
2024
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35. Diagnosis and Treatment of Perilymphatic Fistula.

Author

Deveze A, Matsuda H, Elziere M, and Ikezono T

Subjects
Fistula etiology, Humans, Labyrinth Diseases etiology, Fistula diagnosis, Fistula therapy, Labyrinth Diseases diagnosis, Labyrinth Diseases therapy, Perilymph
Abstract

Perilymphatic fistula (PLF) is defined as an abnormal communication between the fluid (perilymph)-filled space of the inner ear and the air-filled space of the middle ear and mastoid, or cranial spaces. PLF is located in the round or oval window, fractured bony labyrinth, microfissures, anomalous footplate, and can occur after head trauma or barotrauma, chronic inflammation, or in otic capsule dehiscence. This clinical entity was initially proposed more than a century ago, yet it has remained a topic of controversy for more than 50 years. The difficulty of making a definitive diagnosis of PLF has caused a long-standing debate regarding its prevalence, natural history, management and even its very existence. In this present study, we will discuss the symptoms, physiological tests (focusing on vestibular assessment) and imaging studies. Referring to a previous criticism, we will share our classification of PLF into 4 categories. Furthermore, we will summarize a nationwide survey using a novel and widely used biomarker (Cochlin-tomoprotein [CTP]) for PLF diagnosis in Japan and present the results of the new diagnostic criteria. PLF is surgically correctable by sealing the fistula, and appropriate recognition and treatment of PLF can improve hearing and balance, and in turn, improve the quality of life of afflicted patients. Therefore, PLF is an especially important treatable disease for otologists., (© 2018 S. Karger AG, Basel.)

Published
2018
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36. [Two cases of allergic fungal rhinosinusitis with bone destruction].

Author

Inoue T, Kamijo A, Nakajima M, Matsuda H, Inoue H, Sugasawa M, and Kase H

Subjects
Adult, Biomarkers blood, Diagnosis, Differential, Humans, Immunoglobulin E blood, Magnetic Resonance Imaging, Male, Orbit microbiology, Orbit pathology, Paranasal Sinuses diagnostic imaging, Rhinitis, Allergic, Rhinitis, Allergic, Perennial diagnosis, Rhinitis, Allergic, Perennial therapy, Sinusitis diagnosis, Sinusitis therapy, Skull Base microbiology, Skull Base pathology, Tomography, X-Ray Computed, Young Adult, Mycoses, Paranasal Sinuses microbiology, Paranasal Sinuses pathology, Rhinitis, Allergic, Perennial microbiology, Rhinitis, Allergic, Perennial pathology, Sinusitis microbiology, Sinusitis pathology
Abstract

We report herein two cases of allergic fungal rhinosinusitis accompanied by bone destruction of the adjacent nasal sinuses. The first case involved a 21-year-old man who presented with left exophthalmos. Computed tomography (CT) showed soft tissue lesions in the left paranasal sinuses and destruction of the left lamina papyraceae, as well as infiltration of the lesion into the orbit. In the second case, a 39-year-old man, CT showed bone destruction of the skull base and medial wall of the left orbit. In both cases, total serum immunoglobulin (Ig)E level was >1000 IU/mL and fungus-specific IgEs were increased. Fungal hyphae were identified within the mucus on histopathological examination in both cases; however, no fungal invasion of the mucosa was apparent. Final diagnosis was allergic fungal rhinosinusitis (AFRS) in both cases. AFRS is a relatively new disease concept that was proposed in the early 1980s, with disease characteristics very similar to eosinophilic rhinosinusitis. Occasionally, AFRS must be differentiated from malignant disease or invasive fungal rhinosinusitis, so an understanding of the clinical features is important.

Published
2014

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