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21 results on '"Matsuyama, Hiromi"'

2. Group III secreted phospholipase A2‐driven lysophospholipid pathway protects against allergic asthma

Author

Hamu‐Tanoue, Asako, primary, Takagi, Koichi, additional, Taketomi, Yoshitaka, additional, Miki, Yoshimi, additional, Nishito, Yasumasa, additional, Kano, Kuniyuki, additional, Aoki, Junken, additional, Matsuyama, Takahiro, additional, Kondo, Kiyotaka, additional, Dotake, Yoichi, additional, Matsuyama, Hiromi, additional, Machida, Kentaro, additional, Murakami, Makoto, additional, and Inoue, Hiromasa, additional

Published
2024
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7. The Therapeutic Potential for Targeting Group 2 Innate Lymphoid Cells in Asthma

Author

Matsuyama, Takahiro, Matsuyama, Hiromi, Dotake, Yoichi, Takagi, Koichi, Machida, Kentaro, and Inoue, Hiromasa

Subjects
Inflammation, Mice, Immunology, Quality of Life, Animals, Cytokines, Humans, Immunology and Allergy, Lymphocytes, Asthma, Immunity, Innate
Abstract

T helper type 2 cells (Th2 cells) and group 2 innate lymphoid cells (ILC2s) play an important role in the pathophysiology of asthma, including airway eosinophilic inflammation. ILC2s are activated by epithelial-derived cytokines [interleukin-25 (IL-25), IL-33, and thymic stromal lymphopoietin (TSLP)] from airway epithelial cells, leading to the release of high amounts of type 2 cytokines, such as IL-5 and IL-13. ILC2s induce airway inflammation in an antigen-independent manner, and ILC2s are considered to be involved in the pathogenesis of asthma exacerbation. Furthermore, ILC2 activation might also confer steroid resistance. Many recent studies in humans and mice are increasingly demonstrating that the function of ILC2s is regulated not just by epithelial-derived cytokines but by a variety of cytokines and mediators derived from innate immune cells. Furthermore, the biologics targeting these cytokines and/or their receptors have been shown to reduce asthma exacerbations and improve lung function and quality of life in asthmatics. This article reviews the current treatment landscape for type 2 airway inflammation in asthma and discusses the therapeutic potential for targeting ILC2s.

Published
2022
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13. Evaluation of dry matter production and yield in early-sown wheat using near-isogenic lines for the vernalization locus Vrn-D1

Author

Sawada, Hiroko, primary, Matsuyama, Hiromi, additional, Matsunaka, Hitoshi, additional, Fujita, Masaya, additional, Okamura, Natsumi, additional, Seki, Masako, additional, Kojima, Hisayo, additional, Kiribuchi-Otobe, Chikako, additional, Takayama, Toshiyuki, additional, Oda, Shunsuke, additional, Nakamura, Kazuhiro, additional, Sakai, Tetsufumi, additional, Matsuzaki, Morio, additional, and Kato, Kenji, additional

Published
2019
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14. The effects of seeding rate on yield, lodging resistance and culm strength in wheat.

Author

Matsuyama, Hiromi and Ookawa, Taiichiro

Subjects
SEED yield, DATA acquisition systems, BENDING moment, BENDING stresses, YOUNG'S modulus
Abstract

We compared the effects of four seeding rates, 60, 100, 140, and 180 seeds m−2, on yield, lodging resistance and culm strength using two Japanese wheat cultivars Ayahikari and Iwainodaichi. With the decreasing seeding rate, maximum tiller number decreased, percentage of productive culms increased and spike number m−2 decreased, and the spikelet number per spike, percentage of fertile spikelets, grain number per spikelet and grain number per spike increased. Consequently, grain yield was not significantly affected. Lodging was not observed, but the lodging index was significantly affected by the seeding rate and was the highest in the plots sown at 180 seeds m−2. The bending moment at the breaking point and flexural rigidity of the basal internode with leaf sheaths were highest in the plots sown at 60 seeds m−2. In conclusion, the culm strength and stem lodging resistance increased with decreasing seeding rate. Section modulus and bending stress, which constitute the bending moment at the breaking point, and the moment of inertia area and Young's modulus, which represent the flexural rigidity, were highest in plots sown at 60 seeds m−2. Therefore, the seeding rate was considered to influence the culm morphology and functions of the cell wall components. The effects of the seeding rate on culm characteristics and lodging resistance did not differ between the two cultivars, and 'Ayahikari' had consistently stronger culms than 'Iwainodaichi'. We suggest that low seeding rates method would be suitable for heavily fertilized cultivation for both cultivar with high and low culm strength. AMeDAS: the automated meteorological data acquisition system; HSD: honestly significant difference [ABSTRACT FROM AUTHOR]

Published
2020
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15. Differences in Growth Properties between Near-isogenic Wheat Lines Carrying Different Types of Vrn-D1 in the Genetic Background of Two Early Cultivars.

Author

Matsuyama, Hiromi, primary, Seki, Masako, additional, Shimazaki, Yumi, additional, Kojima, Hisayo, additional, Kiribuchi-Otobe, Chikako, additional, Takayama, Toshiyuki, additional, Ohshita, Yasuo, additional, Fujita, Masaya, additional, Watanabe, Yoshiaki, additional, Oda, Shunsuke, additional, and Kato, Kenji, additional

Published
2017
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17. Growth and Yield Properties of Near-Isogenic Wheat Lines Carrying Different Photoperiodic Response Genes

Author

Matsuyama, Hiromi, primary, Fujita, Masaya, additional, Seki, Masako, additional, Kojima, Hisayo, additional, Shimazaki, Yumi, additional, Matsunaka, Hitoshi, additional, Chono, Makiko, additional, Hatta, Kouichi, additional, Kubo, Katashi, additional, Takayama, Toshiyuki, additional, Kiribuchi-Otobe, Chikako, additional, Oda, Shunsuke, additional, Watanabe, Yoshiaki, additional, and Kato, Kenji, additional

Published
2015
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21. A Case of Interstitial Pneumonia Leading to Respiratory Failure Several Months After COVID-19 Infection.

Author

Kashima K, Matsuyama H, Yoshishige Y, and Nakazono S

Abstract

While acute pneumonia is commonly observed in the early stages of coronavirus disease 2019 (COVID-19) infection, isolated cases of interstitial pneumonia have been reported several months later. In this case, interstitial lung disease was identified on a routine follow-up examination five months after infection. Eight months after infection, the patient developed worsening interstitial lung disease, pulmonary hypertension, and worsening symptoms, leading to respiratory failure. Careful follow-up is necessary for patients with COVID-19 who experience progressive pulmonary lesions., Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2025, Kashima et al.)

Published
2025
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