908 results on '"Mattevi, Andrea"'
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2. Targeting ROS production through inhibition of NADPH oxidases
3. Evolution of enzyme functionality in the flavin-containing monooxygenases
4. Structure, Function and Mechanism of Six-Transmembrane Epithelial Antigen of the Prostate (STEAP) Enzymes : Insights into a Transmembrane Oxidoreductase Family Related to NADPH Oxidases
5. Structure, mechanism, and evolution of the last step in vitamin C biosynthesis
6. Discovery and biochemical characterization of thermostable glycerol oxidases
7. Impact of ancestral sequence reconstruction on mechanistic and structural enzymology
8. A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center
9. The NPAC-LSD2 complex in nucleosome demethylation
10. Crystallization of Human Monoamine Oxidase B
11. Asymmetric Engagement of Dimeric CRL3KBTBD4by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes
12. Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound
13. Evolutionary and structural analyses of the NADPH oxidase family in eukaryotes reveal an initial calcium dependency
14. Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism
15. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
16. Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
17. LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer
18. In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis
19. Efficient Oxidation of 5‐Hydroxymethylfurfural Using a Flavoprotein Oxidase from the Honeybee Apis mellifera
20. Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs
21. Deciphering the enzymatic mechanism of sugar ring contraction in UDP-apiose biosynthesis
22. Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer
23. Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
24. Structure elucidation and characterization of patulin synthase, insights into the formation of a fungal mycotoxin
25. The multipurpose family of flavoprotein oxidases
26. Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO)
27. Three-Dimensional Structure of Human Monoamine Oxidase A (MAO A): Relation to the Structures of Rat MAO A and Human MAO B
28. Crystal Structure of a Baeyer-Villiger Monooxygenase
29. Crystal structures and atomic model of NADPH oxidase
30. Expanding the structural biology toolbox with single-molecule holography
31. Endogenous human NADPH oxidase 2: revealing the insights for a structure-driven drug discovery
32. In-silico and in-vitro compound screening presents promise in NADPH oxidases drug development
33. Insights into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
34. Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
35. One-Pot Biocatalytic Synthesis of rac-Syringaresinol from a Lignin-Derived Phenol.
36. Inversion of Stereospecificity of Vanillyl-Alcohol Oxidase
37. Crystal Structure of D-Amino Acid Oxidase: A Case of Active Site Mirror-Image Convergent Evolution with Flavocytochrome b2
38. At Long Last Potent and Selective KDM5 Inhibitors
39. Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction
40. Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts
41. Architecture of the NADPH oxidase family of enzymes
42. Discovery and characterization of an F420-dependent glucose-6-phosphate dehydrogenase (Rh-FGD1) from Rhodococcus jostii RHA1
43. Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation
44. Monoamine Oxidase Inhibitors: Diverse and Surprising Chemistry with Expanding Pharmacological Potential
45. Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: A novel class of irreversible inhibitors of histone demethylase KDM1A
46. Publisher Correction: Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs
47. Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase
48. Rationally Guided Improvement of NOV1 Dioxygenase for the Conversion of Lignin-Derived Isoeugenol to Vanillin
49. Architecture of the NADPH oxidase family of enzymes
50. Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease
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