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8 results on '"Matzaras, Rafail"'

1. Antimicrobial Use during the SARS-CoV-2 Pandemic in a Greek Tertiary University Hospital

Author

Biros, Dimitrios, primary, Filippas-Ntekouan, Sempastian, additional, Limperatou, Diamantina, additional, Liontos, Angelos, additional, Matzaras, Rafail, additional, Tsarapatsani, Konstantina-Helen, additional, Kolios, Nikolaos-Gavriel, additional, Pappa, Christiana, additional, Nasiou, Maria, additional, Pargana, Eleni, additional, Tsiakas, Ilias, additional, Samanidou, Valentini, additional, Athanasiou, Lazaros, additional, Konstantopoulou, Revekka, additional, Milionis, Haralampos, additional, and Christaki, Eirini, additional

Published
2024
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2. Inflammation and Venous Thromboembolism in Hospitalized Patients with COVID-19

Author

Liontos, Angelos, primary, Biros, Dimitrios, additional, Matzaras, Rafail, additional, Tsarapatsani, Konstantina-Helen, additional, Kolios, Nikolaos-Gavriel, additional, Zarachi, Athina, additional, Tatsis, Konstantinos, additional, Pappa, Christiana, additional, Nasiou, Maria, additional, Pargana, Eleni, additional, Tsiakas, Ilias, additional, Lymperatou, Diamantina, additional, Filippas-Ntekouan, Sempastien, additional, Athanasiou, Lazaros, additional, Samanidou, Valentini, additional, Konstantopoulou, Revekka, additional, Vagias, Ioannis, additional, Panteli, Aikaterini, additional, Milionis, Haralampos, additional, and Christaki, Eirini, additional

Published
2023
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4. Glycemic Dysregulation, Inflammation and Disease Outcomes in Patients Hospitalized with COVID-19: Beyond Diabetes and Obesity

Author

Liontos, Angelos, primary, Biros, Dimitrios, additional, Kavakli, Aikaterini, additional, Matzaras, Rafail, additional, Tsiakas, Ilias, additional, Athanasiou, Lazaros, additional, Samanidou, Valentini, additional, Konstantopoulou, Revekka, additional, Vagias, Ioannis, additional, Panteli, Aikaterini, additional, Pappa, Christiana, additional, Kolios, Nikolaos-Gavriel, additional, Nasiou, Maria, additional, Pargana, Eleni, additional, Milionis, Haralampos, additional, and Christaki, Eirini, additional

Published
2023
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6. Multicentre Surveillance of Candida Species from Blood Cultures during the SARS-CoV-2 Pandemic in Southern Europe (CANCoVEU Project)

Author

Boattini, Matteo, primary, Pinto, Margarida Feijó, additional, Christaki, Eirini, additional, Fasciana, Teresa, additional, Falces-Romero, Iker, additional, Tofarides, Andreas, additional, Bianco, Gabriele, additional, Cendejas-Bueno, Emilio, additional, Tricoli, Maria Rita, additional, Tsiolakkis, Giorgos, additional, García-Rodríguez, Julio, additional, Matzaras, Rafail, additional, Comini, Sara, additional, Giammanco, Anna, additional, Kasapi, Diamanto, additional, Almeida, André, additional, Gartzonika, Konstantina, additional, Cavallo, Rossana, additional, and Costa, Cristina, additional

Published
2023
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8. Gut Microbiota Modulation and Prevention of Dysbiosis as an Alternative Approach to Antimicrobial Resistance: A Narrative Review.

Author

Matzaras R, Nikopoulou A, Protonotariou E, and Christaki E

Subjects
Humans, Anti-Bacterial Agents pharmacology, Dysbiosis drug therapy, Dysbiosis microbiology, Drug Resistance, Bacterial, Fecal Microbiota Transplantation, Gastrointestinal Microbiome, Probiotics pharmacology, Probiotics therapeutic use
Abstract

Background : The importance of gut microbiota in human health is being increasingly studied. Imbalances in gut microbiota have been associated with infection, inflammation, and obesity. Antibiotic use is the most common and significant cause of major alterations in the composition and function of the gut microbiota and can result in colonization with multidrug-resistant bacteria. Methods : The purpose of this review is to present existing evidence on how microbiota modulation and prevention of gut dysbiosis can serve as tools to combat antimicrobial resistance. Results : While the spread of antibiotic-resistant pathogens requires antibiotics with novel mechanisms of action, the number of newly discovered antimicrobial classes remains very low. For this reason, the application of alternative modalities to combat antimicrobial resistance is necessary. Diet, probiotics/prebiotics, selective oropharyngeal or digestive decontamination, and especially fecal microbiota transplantation (FMT) are under investigation with FMT being the most studied. But, as prevention is better than cure, the implementation of antimicrobial stewardship programs and strict infection control measures along with newly developed chelating agents could also play a crucial role in decreasing colonization with multidrug resistant organisms. Conclusion : New alternative tools to fight antimicrobial resistance via gut microbiota modulation, seem to be effective and should remain the focus of further research and development., (Copyright ©2022, Yale Journal of Biology and Medicine.)

Published
2022

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