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5. Hemodynamic Performances and Clinical Outcomes in Patients Undergoing Valve-in-Valve Versus Native Transcatheter Aortic Valve Implantation

Author

Akodad, Mariama, Meilhac, Alexandra, Lefèvre, Thierry, Cayla, Guillaume, Lattuca, Benoit, Autissier, Cécile, Duflos, Claire, Gandet, Thomas, Macia, Jean-Christophe, Delseny, Delphine, Roubille, Francois, Maupas, Eric, Schmutz, Laurent, Piot, Christophe, Targosz, Frédéric, Robert, Gabriel, Rivalland, François, Albat, Bernard, Chevalier, Bernard, and Leclercq, Florence

Published
2019
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6. C-reactive protein and prognosis after percutaneous coronary intervention and bypass graft surgery for left main coronary artery disease: Analysis from the EXCEL trial

Author

Kosmidou, Ioanna, Redfors, Björn, Chen, Shmuel, Crowley, Aaron, Lembo, Nicholas J., Karmpaliotis, Dimitri, Brown, W. Morris, III, Maupas, Eric, Durrleman, Nicolas, Shah, Alpesh, Reardon, Michael J., Dressler, Ovidiu, Ben-Yehuda, Ori, Kappetein, Arie Pieter, Sabik, Joseph F., III, Serruys, Patrick W., and Stone, Gregg W.

Published
2019
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17. Myocardial Injury After Balloon Predilatation Versus Direct Transcatheter Aortic Valve Replacement: Insights From the DIRECTAVI Trial

Author

Akodad, Mariama, primary, Roubille, François, additional, Marin, Gregory, additional, Lattuca, Benoit, additional, Macia, Jean‐Christophe, additional, Delseny, Delphine, additional, Gandet, Thomas, additional, Robert, Pierre, additional, Schmutz, Laurent, additional, Piot, Christophe, additional, Maupas, Eric, additional, Robert, Gabriel, additional, Targosz, Frederic, additional, Albat, Bernard, additional, Cayla, Guillaume, additional, and Leclercq, Florence, additional

Published
2020
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20. Abnormal coactivation of knee and ankle extensors is related to changes in heteronymous spinal pathways after stroke

Author

Bourbonnais Daniel, de Andrade Melo Sibele, Maupas Eric, Dyer Joseph-Omer, and Forget Robert

Subjects
Hemiparesis, Extension synergy, Sensory afferents, Isometric strength, Spinal Circuits, Propriospinal, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Abstract Background Abnormal coactivation of leg extensors is often observed on the paretic side of stroke patients while they attempt to move. The mechanisms underlying this coactivation are not well understood. This study (1) compares the coactivation of leg extensors during static contractions in stroke and healthy individuals, and (2) assesses whether this coactivation is related to changes in intersegmental pathways between quadriceps and soleus (Sol) muscles after stroke. Methods Thirteen stroke patients and ten healthy individuals participated in the study. Levels of coactivation of knee extensors and ankle extensors were measured in sitting position, during two tasks: maximal isometric voluntary contractions in knee extension and in plantarflexion. The early facilitation and later inhibition of soleus voluntary EMG evoked by femoral nerve stimulation were assessed in the paretic leg of stroke participants and in one leg of healthy participants. Results Coactivation levels of ankle extensors (mean ± SEM: 56 ± 7% of Sol EMG max) and of knee extensors (52 ± 10% of vastus lateralis (VL) EMG max) during the knee extension and the ankle extension tasks respectively were significantly higher in the paretic leg of stroke participants than in healthy participants (26 ± 5% of Sol EMG max and 10 ± 3% of VL EMG max, respectively). Early heteronymous facilitation of Sol voluntary EMG in stroke participants (340 ± 62% of Sol unconditioned EMG) was significantly higher than in healthy participants (98 ± 34%). The later inhibition observed in all control participants was decreased in the paretic leg. Levels of coactivation of ankle extensors during the knee extension task were significantly correlated with both the increased facilitation (Pearson r = 0.59) and the reduced inhibition (r = 0.56) in the paretic leg. Measures of motor impairment were more consistently correlated with the levels of coactivation of biarticular muscles than those of monoarticular muscles. Conclusion These results suggest that the heteronymous pathways linking quadriceps to soleus may participate in the abnormal coactivation of knee and ankle extensors on the paretic side of stroke patients. The motor impairment of the paretic leg is strongly associated with the abnormal coactivation of biarticular muscles.

Published
2011
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21. Temporal Trends in Transcatheter Aortic Valve Replacement in France: FRANCE 2 to FRANCE TAVI

Author

Auffret, Vincent, Lefevre, Thierry, Belle, Eric, Eltchaninoff, Hélène, Iung, Bernard, Koning, René, Motreff, Pascal, Leprince, Pascal, Philippe, Philippe, Manigold, Thibaut, Souteyrand, Geraud, Boulmier, Dominique, Joly, Patrick, Pinaud, Frédéric, Himbert, Dominique, Collet, Philippe, Rioufol, Gilles, Ghostine, Said, Bar, Olivier, Dibie, Alain, Champagnac, Didier, Leroux, Lionel, Collet, Frédéric, Teiger, Emmanuel, Darremont, Olivier, Folliguet, Thierry, Leclercq, Florence, Lhermusier, Thibault, Olhmann, Patrick, Huret, Bruno, Lorgis, Luc, Drogoul, Laurent, Bertrand, Bernard, Spaulding, Christian, Quilliet, Laurent, Cuisset, Thomas, Delomez, Max, Beygui, Farzin, Claudel, Philippe, Hepp, Alain, Jégou, Arnaud, Gommeaux, Antoine, Mirode, Anfani, Christiaens, Luc, Christophe, Christophe, Cassat, Claude, Metz, Damien, MANGIN, Lionel, Isaaz, Karl, Jacquemin, Laurent, Guyon, Philippe, Pouillot, Christophe, Makowski, Serge, Bataille, Vincent, Rodes-Cabau, Josep, Gilard, Martine, Laskar, Marc, Chevalier, Bernard, Hovasse, Thomas, Donzeau Gouge, Patrick, Farge, Arnaud, Romano, Mauro, Bertrand, Bertrand, Bouvier, Erik, Bauchart, Jean, Delhaye, Cédric, Houpe, David, Robert, Robert, Leroy, Fabrice, Sudre, Arnaud, Juthier, Francis, Koussa, Mohamed, Modine, Thomas, Rousse, Natacha, Auffray, Jean, Richard, Richard, Berland, Jacques, Godin, Mathieu, Bessou, Jean, Letocart, Vincent, Roussel, Jean, Combaret, Nicolas, d’Ostrevy, Nicolas, Innorta, Andrea, Clerfond, Guillaume, Vorilhon, Charles, Bedossa, Marc, Leurent, Guillaume, Anselmi, Amedeo, Harmouche, Majid, Donal, Erwan, Bille, Jacques, Houel, Rémi, Abi Khalil, Wissam, Delepine, Stéphane, Fouquet, Olivier, Roule, Frédéric, Abtan, Jérémie, Urena, Marina, Alkhoder, Soleiman, Ghodbane, Walid, Arangalage, Dimitri, Brochet, Eric, Goublaire, Coppelia, Choussat, Rémi, Lebreton, Guillaume, Mastrioanni, Chiro, Dauphin, Raphaël, Dubreuil, Olivier, Durand de Gevigney, Guy, Finet, Gérard, Harbaoui, Brahim, Ranc, Sylvain, Farhat, Fadi, Jegaden, Olivier, Obadia, Jean, Pozzi, Matteo, Ghostine, Saïd, Fradi, Sahbi, Azmoun, Alexandre, Kauffmann, Martin, Blanchard, Didier, Chassaing, Stephan, Chatel, Didier, Le Page, Olivier, Tauran, Arnaud, Bruere, Didier, Bodson, Laurent, Meurisse, Yvon, Seemann, Aurélie, AMABILE, NICOLAS, Simon, Simon, Drieu, Luc, Ohanessian, Alice, Veugeois, Aurélie, Debauchez, Matthieu, Zannis, Konstantinos, Czitrom, Daniel, Diakov, Chrystelle, Raoux, François, Lienhart, Yves, Staat, Patrick, Zouaghi, Oualid, Doisy, Vincent, Frieh, Philippe, Wautot, Fabrice, Dementhon, Julie, Garrier, Olivier, Jamal, Fadi, Leroux, Pierre, Casassus, Frédéric, Séguy, Benjamin, Barandon, Laurent, Labrousse, Louis, Peltan, Julien, Cornolle, Claire, Dijos, Marina, Lafitte, Stephane, Bayet, Gilles, Charmasson, Claude, Vaillant, Alain, Vicat, Jacques, Giacomoni, Marie Paule, Bergoend, Eric, Zerbib, Céline, Louis Leymarie, Jean, Clerc, Philippe, Choukroun, Emmanuel, Elia, Nicolas, Grimaud, Philippe, Guibaud, Philippe, Wroblewski, Stéphane, Abergel, Eric, Bogino, Emmanuel, Dehant, Patrick, Simon, Marc, Angioi, Michel, Lemoine, Julien, Lemoine, Simon, Popovic, Batric, Maureira, Pablo, Huttin, Olivier, Selton Suty, Christine, Cayla, Guillaume, Delseny, Delphine, Levy, Gilles, Maupas, Eric, Rivalland, François, Robert, Gabriel, Schmutz, Laurent, Targosz, Frédéric, Albat, Bernard, Dubar, Arnaud, Durrleman, Nicolas, Gandet, Thomas, Munos, Emmanuel, Cade, Stéphane, Cransac, Frédéric, Bouisset, Frédéric, Grunenwald, Etienne, Bertrand, Marc, Fournier, Pauline, Morel, Olivier, Ohlmann, Patrick, Kindo, Michel, Hoang, Minh Tam, Petit, Hélène, Samet, Hafida, Trinh, Anne, Lecoq, Guillaume, Morelle, Jean François, Richard, Pascal, Derieux, Thierry, Monier, Emmanuel, Joret, Cédric, Bouchot, Olivier, Meyer, Pierre, Lopez, Stéphane, Tapia, Michel, Teboul, Jacques, Elbeze, Pierre, Mihoubi, Alain, Vanzetto, Gérald, Wittenberg, Olivier, Bach, Vincent, Martin, Cécile, Sauier, Carole, Casset, Charlotte, Castellant, Philippe, Bezon, Eric, Choplain, Jean, Kallifa, Ahmed, Nasr, Bahaa, Jobic, Yannick, Lafont, Antoine, Pagny, Jean, Abi Akar, Ramzi, Fabiani, Jean, Zegdi, Rachid, Berrebi, Alain, Puscas, Tania, Desveaux, Bernard, Ivanes, Fabrice, Bourguignon, Thierry, Aupy, Blandine, Perault, Romain, Bonnet, Jean, Lambert, Marc, Grisoli, Dominique, Jaussaud, Nicolas, Salaün, Erwan, Laghzaoui, Amine, Savoye, Christine, Bignon, Mathieu, Roule, Vincent, Sabatier, Rémy, Ivascau, Calin, Saplacan, Vladimir, Saloux, Eric, Bouchayer, Damien, Tremeau, Guillaume, Diab, Camille, Lapeze, Joel, Pelissier, Franck, Sassard, Thomas, Matz, Catherine, Monsarrat, Nicolas, Carel, Ivan, Sibellas, Franck, Curtil, Alain, Dambrin, Grégoire, Favereau, Xavier, Ghorayeb, Gabriel, Guesnier, Laurent, Khoury, Wassim, Pouzet, Bruno, Vaislic, Claude, Cheikh-Khelifa, Riadh, Hilpert, Loïc, Maribas, Philippe, Hannebicque, Gery, Hochart, Philippe, Paris, Marc, Pecheux, Max, Fabre, Olivier, Leborgne, Laurent, Peltier, Marcel, Le Breton, Hervé, Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], Hôpital Privé Jacques Cartier [Massy], Pole Cardio-vasculaire et pulmonaire [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de cardiologie [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Service de cardiologie [CHU Bichat], AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot, Sorbonne Paris Cité, Clinique St Hilaire ( Service de Cardiologie, Rouen), CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand, Image Science for Interventional Techniques (ISIT), Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université-Centre National de la Recherche Scientifique (CNRS), Service de Chirurgie cardiaque et thoracique [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Cardiologie [Nantes], Centre hospitalier universitaire de Nantes (CHU Nantes), Hôpital Saint-Joseph [Marseille], Service de chirurgie cardio-vasculaire et thoracique, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Service de cardiologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Institut de cardiologie [CHU Pitié-Salpêtrière], Hôpital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon (HCL), Centre Chirurgical Marie Lannelongue (CCML), Clinique St Gatien et Groupe Athérome Cardiologie Interventionnelle/SF, Clinique St Gatien, Institut Mutualiste de Montsouris (IMM), Clinique du Tonkin, Hôpital Haut-Lévêque [CHU Bordeaux], CHU Bordeaux [Bordeaux], Hôpital Privé Clairval [Marseille], Centre d'Investigation Clinique Henri Mondor (CIC Henri Mondor), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Clinique Saint Augustin, Service de Cardiologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de cardiologie [Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de cardiologie [Toulouse], CHU Strasbourg, Hôpital Privé Saint Martin Caen, Service de Cardiologie [CHU de Dijon], Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Institut Arnaud Tzanck, Centre Hospitalier Universitaire [Grenoble] (CHU), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Cardiologie (CHU Trousseau, Tours), CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Nanomédecine Régénérative (NanoRegMed), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Polyclinic du Bois, Service de cardiologie et de pathologie vasculaire [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Infirmerie Protestante Lyon Caluire, parent, Clinique de la Sauvegarde [Lyon], Parly II Private Hospital, Le Chesnay, Hôpital privé Bois-Bernard, Service de Cardiologie [Amiens], CHU Amiens-Picardie, Hôpital de la Milétrie, Centre hospitalier universitaire de Poitiers (CHU Poitiers), Centre hospitalier régional Metz-Thionville (CHR Metz-Thionville), Hôpital Dupuytren [CHU Limoges], Hôpital universitaire Robert Debré [Reims], Centre Hospitalier Annecy-Genevois [Saint-Julien-en-Genevois], Hôpital Nord (Saint Etienne), Centre Hospitalier Emile Muller [Mulhouse] (CH E.Muller Mulhouse), Groupe Hospitalier de Territoire Haute Alsace (GHTHA), Centre cardiologique du Nord (CCN), Clinique Sainte Clotilde, Hôpital Ambroise Paré [AP-HP], Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval [Québec] (ULaval), Optimisation des régulations physiologiques (ORPHY (EA 4324)), Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO), Service de Chirurgie Thoracique et Vasculaire - Médecine vasculaire [CHU Limoges], CHU Limoges, Unité de Taphonomie médico-légale et Anatomie - ULR 7367 (UTML&A), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Hémostase et pathologie cardiovasculaire, EA2693-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, chirurgie thoracique et cardio-vasculaire, Service de chirurgie cardiaque, Service de chirurgie thoracique cardiaque et vasculaire [Rennes] = Thoracic and Cardiovascular Surgery [Rennes], Microbiology Institute of CHUV, Service de Cardiologie de l'hopital de la Croix Rousse, Department of Hemodynamics and Interventional Cardiology, Institut National de la Santé et de la Recherche Médicale (INSERM), Cardiology Department, European Society of Hypertension Excellence Center, Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Service de chirurgie cardiaque et transplantation, Hôpital Louis Pradel [CHU - HCL], Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pôle Cardiologie Interventionnelle / Coro-scanner / IRM Cardiaque, Clinique Saint Gatien, Hôpital nord, St Etienne, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Département de cardiologie, CHU Bordeaux [Bordeaux]-Hôpital Haut-Lévêque [CHU Bordeaux], Adaptation cardiovasculaire à l'ischemie, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Chirurgie cardio-vasculaire, Service de Cardiologie [CHU Saint-Antoine], CHU Saint-Antoine [AP-HP], École de chirurgie, faculté de médecine de Nancy, Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Service de chirurgie thoracique et cardio-vasculaire, Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Arnaud de Villeneuve-Université de Montpellier (UM), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), European Synchrotron Radiation Facility (ESRF), Service de Cardiologie (BREST - Cardio), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Service d'urologie, Clinique Cardiologie et Hypertension Artérielle, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Hôpital Michallon, Clinique de chirurgie cardiaque, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Service de Cardiologie, Brest, Hôpital de la Cavale Blanche - CHRU Brest (CHU - BREST ), Développement artériel, Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Gynécologie‑Obstétrique, Signalisation, électrophysiologie et imagerie des lésions d’ischémie-reperfusion myocardique (SEILIRM), Normandie Université (NU)-Normandie Université (NU), Service de cardiologie et maladies vasculaires [CHU de Rennes], Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Université Paris Diderot - Paris 7 (UPD7)-AP-HP - Hôpital Bichat - Claude Bernard [Paris]-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Gabriel Montpied (CHU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Henri Mondor-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Pathologie cardiaque, Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], CHU Dijon, Rayonnement Synchrotron et Recherche Medicale (RSRM), Université Joseph Fourier - Grenoble 1 (UJF)-European Synchrotron Radiation Facility (ESRF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Descartes - Paris 5 (UPD5)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Cardiologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université, Epidémiologie et Biostatistique, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre Hospitalier Universitaire de Clermont-Ferrand, Service de chirurgie thoracique cardiaque et vasculaire [Rennes], Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Service de Chirurgie Thoracique et Cardiovasculaire [CHU Pitié-Salpêtrière], Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université-Sorbonne Université, Hôpital Arnaud de Villeneuve-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Université de Montpellier (UM), Hôpital Paule de Viguier, Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre chirurgical Marie Lannelongue, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire Traitement du Signal et de l'Image ( LTSI ), Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Service de cardiologie [Rouen], CHU Rouen-Université de Rouen Normandie ( UNIROUEN ), Normandie Université ( NU ) -Normandie Université ( NU ), Assistance publique - Hôpitaux de Paris (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris]-Université Paris Diderot - Paris 7 ( UPD7 ), Clinique St Hilaire ( Service de Cardiologie, Rouen ), CHU Gabriel Montpied ( CHU ), Assistance publique - Hôpitaux de Paris - AP-HP (FRANCE), CHU Angers, Hospices Civils de Lyon ( HCL ), Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Centre d'Investigation Clinique Henri Mondor ( CIC Henri Mondor ), Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Henri Mondor-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris-Est Créteil Val-de-Marne - Paris 12 ( UPEC UP12 ), Institut Mutualiste de Montsouris ( IMM ), Centre Hospitalier Régional Universitaire [Montpellier] ( CHRU Montpellier ), Université Toulouse III - Paul Sabatier ( UPS ), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital de Rangueil, CHU Toulouse [Toulouse], Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon ), Rayonnement Synchrotron et Recherche Medicale ( RSRM ), Université Joseph Fourier - Grenoble 1 ( UJF ) -ESRF-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Paris-Centre de Recherche Cardiovasculaire ( PARCC - U970 ), Hôpital Européen Georges Pompidou [APHP] ( HEGP ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Nutrition, obésité et risque thrombotique ( NORT ), Aix Marseille Université ( AMU ) -Institut National de la Recherche Agronomique ( INRA ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Centre hospitalier universitaire de Poitiers ( CHU Poitiers ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Épidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Institut Universitaire de Cardiologie et de Pneumologie de Québec ( IUCPQ ), Université Laval, Optimisation des régulations physiologiques ( ORPHY (EA 4324) ), Université de Brest ( UBO ) -Centre Hospitalier Régional Universitaire de Brest ( CHRU Brest ) -Institut Brestois Santé Agro Matière ( IBSAM ), Université de Brest ( UBO ) -Université de Brest ( UBO ), Unité de Taphonomie médico-légale ( UTML ), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] ( CHRU Lille ), Centre Hospitalier Régional Universitaire [Lille] ( CHRU Lille ), EA2693-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université de Lille, Droit et Santé, Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Institut National de la Santé et de la Recherche Médicale ( INSERM ), Hospices Civils de Lyon ( HCL ) -Hospices Civils de Lyon ( HCL ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Hôpital Louis Pradel [CHU - HCL], Cardiovasculaire, métabolisme, diabétologie et nutrition ( CarMeN ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Hospices Civils de Lyon ( HCL ) -Institut National des Sciences Appliquées de Lyon ( INSA Lyon ), Université de Lyon-Institut National des Sciences Appliquées ( INSA ) -Université de Lyon-Institut National des Sciences Appliquées ( INSA ) -Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Institut National de la Recherche Agronomique ( INRA ), Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 ( UPEC UP12 ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Saint-Antoine [APHP], Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Imagerie Adaptative Diagnostique et Interventionnelle ( IADI ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université de Lorraine ( UL ), Centre Hospitalier Régional Universitaire de Nîmes ( CHRU Nîmes ), Université Montpellier 1 ( UM1 ) -Centre Hospitalier Régional Universitaire [Montpellier] ( CHRU Montpellier ) -Hôpital Arnaud de Villeneuve, Institut des Maladies Métaboliques et Cardiovasculaires ( I2MC ), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), European Synchrotron Radiation Facility ( ESRF ), Service de Cardiologie ( BREST - Cardio ), Centre Hospitalier Régional Universitaire de Brest ( CHRU Brest ), Centre hospitalier universitaire de Nantes ( CHU Nantes ), Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble-Hôpital Michallon, Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble, Université Grenoble Alpes - UFR Médecine ( UGA UFRM ), Université Grenoble Alpes ( UGA ), Hôpital de la Cavale Blanche - CHRU Brest ( CHU - BREST ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Signalisation, électrophysiologie et imagerie des lésions d’ischémie-reperfusion myocardique ( SEILIRM ), Université de Caen Normandie ( UNICAEN ), Départment de cardiologie [Caen], Normandie Université ( NU ) -Normandie Université ( NU ) -CHU Caen, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service Cardiologie [CHU Toulouse], Pôle Cardiovasculaire et Métabolique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] (CHU ST-E), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service Gynécologie [CHU Toulouse], Pôle Femme-Mère-Couple [CHU Toulouse], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris]-Université Paris Diderot - Paris 7 (UPD7), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Henri Mondor-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Unité de Taphonomie médico-légale (UTML), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Saint-Antoine [APHP], Centre Hospitalier Régional Universitaire de Nîmes (CHRU Nîmes), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Arnaud de Villeneuve, and Université Grenoble Alpes (UGA)

Subjects
[ SDV ] Life Sciences [q-bio], [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV]Life Sciences [q-bio], transfemoral, national registry, [ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, outcomes, pacemaker
Abstract

International audience; Background - Transcatheter aortic valve replacement (TAVR) is standard therapy for patients with severe aortic stenosis who are at high surgical risk. However, national data regarding procedural characteristics and clinical outcomes over time are limited. Objectives - The aim of this study was to assess nationwide performance trends and clinical outcomes of TAVR during a 6-year period. Methods - TAVRs performed in 48 centers across France between January 2013 and December 2015 were prospectively included in the FRANCE TAVI (French Transcatheter Aortic Valve Implantation) registry. Findings were further compared with those reported from the FRANCE 2 (French Aortic National CoreValve and Edwards 2) registry, which captured all TAVRs performed from January 2010 to January 2012 across 34 centers. Results - A total of 12,804 patients from FRANCE TAVI and 4,165 patients from FRANCE 2 were included in this analysis. The median age of patients was 84.6 years, and 49.7% were men. FRANCE TAVI participants were older but at lower surgical risk (median logistic European System for Cardiac Operative Risk Evaluation [EuroSCORE]: 15.0% vs. 18.4%; p < 0.001). More than 80% of patients in FRANCE TAVI underwent transfemoral TAVR. Transesophageal echocardiography guidance decreased from 60.7% to 32.3% of cases, whereas more recent procedures were increasingly performed in hybrid operating rooms (15.8% vs. 35.7%). Rates of Valve Academic Research Consortium-defined device success increased from 95.3% in FRANCE 2 to 96.8% in FRANCE TAVI (p < 0.001). In-hospital and 30-day mortality rates were 4.4% and 5.4%, respectively, in FRANCE TAVI compared with 8.2% and 10.1%, respectively, in FRANCE 2 (p

Published
2017
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23. Left atrial appendage occlusion simulation based on three-dimensional printing: new insights into outcome and technique

Author

Ciobotaru, Vlad, primary, Combes, Nicolas, additional, Martin, Claire A., additional, Marijon, Eloi, additional, Maupas, Eric, additional, Bortone, Augustin, additional, Bruguière, Eric, additional, Thambo, Jean-Benoit, additional, Teiger, Emmanuel, additional, Pujadas-Berthault, Pénélope, additional, Ternacle, Julien, additional, and Iriart, Xavier, additional

Published
2018
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24. PRIOR BALLOON VALVULOPLASTY VERSUS DIRECT TRANSCATHETER AORTIC VALVE IMPLANTATION (DIRECTAVI): PRELIMINARY FINDINGS ON THE FIRST 128 RANDOMIZED PATIENTS

Author

Robert, Pierre, primary, Macia, Jean-Christophe, additional, Albat, Bernard, additional, Lattuca, Benoit, additional, Labour, Jessica, additional, Akodad, Mariama, additional, Gandet, Thomas, additional, Schmutz, Laurent, additional, Delseny, Delphine, additional, Maupas, Eric, additional, Piot, Christophe, additional, Targosz, Frédéric, additional, Robert, Gabriel, additional, Cayla, Guillaume, additional, and Leclercq, Florence, additional

Published
2018
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25. Late Outcomes of Transcatheter Aortic Valve Replacement in High-Risk Patients: The FRANCE-2 Registry

Author

Gilard, Martine, Eltchaninoff, Hélène, Donzeau Gouge, Patrick, Chevreul, Karine, Fajadet, Jean, Leprince, Pascal, Leguerrier, Alain, Lievre, Michel, Prat, Alain, Teiger, Emmanuel, Lefevre, Thierry, Tchetche, Didier, Didier, Didier, Himbert, Dominique, Albat, Bernard, Cribier, Alain, Sudre, Arnaud, Blanchard, Didier, Rioufol, Gilles, Collet, Frederic, Houel, Remi, Dos Santos, Pierre, Meneveau, Nicolas, Ghostine, Said, Manigold, Thibaut, Guyon, Philippe, Grisoli, Dominique, Le Breton, Herve, Delpine, Stephane, Favereau, Xavier, Souteyrand, Geraud, Ohlmann, Patrick, Doisy, Vincent, Grollier, Gilles, Gommeaux, Antoine, Claudel, Claude, Bourlon, Francois, Bertrand, Bernard, Laskar, Marc, Iung, Bernard, Bertrand, Michel, Cassagne, Jean, Boschat, Jacques, Lusson, Jean, Mathieu, Pierre, Logeais, Yves, Bessou, Jean-Paul, Chevalier, Bernard, Farge, Arnaud, Garot, Philippe, Hovasse, Thomas, Morice, Claude, Romano, Mauro, Vahdat, Olivier, Farah, Bruno, Carrie, Didier, Dumonteil, Nicolas, Fournial, Gérard, Bertrand, Marc, Nataf, Patrick, Vahanian, Alec, Leclercq, Florence, Piot, Christophe, Schmutz, Laurent, Aubas, Pierre, du Cailar, A., Dubar, A., Durrleman, N., Fargosz, F., Levy, Gilles, Maupas, Eric, Rivalland, François, Robert, G., Tron, Christophe, Juthier, Francis, Modine, Thomas, Van Belle, Eric, Banfi, Carlo, Sallerin, Thierry, Bar, Olivier, Barbey, Christophe, Chassaing, Stephan, Chatel, Didier, Le Page, Olivier, Tauran, Arnaud, Cao, Daniele, Dauphin, Raphael, Durand de Gevigney, Guy, Finet, Gérard, Jegaden, Olivier, Obadia, François, Beygui, Farzin, Collet, Jean-Philippe, Pavie, Alain, Vaillant, Alain, Vicat, Jacques, Wittenberg, Olivier, Joly, Patrick, Rosario, Roger, Bergeron, Patrice, Bille, Jacques, Gelisse, Richard, Couetil, Jean-Paul, Dubois Rande, Jean-Luc, Hayat, Delphine, Fougeres, Emilie, Monin, Jean-Luc, Mouillet, Gauthier, Arsac, Florence, Choukroun, Emmanuel, Dijos, Marina, Guibaud, Jean-Philippe, Leroux, Lionel, Elia, Nicolas, Chocron, Sidney, Schiele, François, Caussin, Christophe, Azmoun, Alexandre, Nottin, Rémi, Tirouvanziam, Ashok, Crochet, Dominique, Gaudin, Régis, Roussel, Jean-Christian, Bonnet, Nicolas, Digne, Franck, Mesnidrey, Patrick, Royer, Thierry, Stratiev, Victor, Bonnet, Jean-Louis, Cuisset, Thomas, Abouliatim, Issal, Bedossa, Marc, Boulmier, Dominique, Verhoye, Philippe, Delepine, Stéphane, Debrux, Jean-Louis, Furber, Alain, Pinaud, Frédéric, Bezon, Eric, Choplain, Jean-Noel, Bical, Oliver, Dambrin, Grégoire, Deleuze, Philippe, Jegou, Arnaud, Lusson, Jean-René, Azarnouch, Kasra, Durel, Nicolas, Innorta, Andrea, Lienhart, Yves, Roriz, Ricardo, Staat, Patrick, Fabiani, Jean-Noël, Lafont, Antoine, Zegdi, Rachid, Heudes, Didier, Kindo, Michel, Mazzucotelli, Jean-Philippe, Zupan, Michel, Ivascau, Calin, Lognone, Thérèse, Massetti, Massimo, Sabatier, Rémy, Huret, Bruno, Hochart, Philippe, Bouchayer, Damien, Gabrielle, François, Pelissier, Franck, Tremeau, Guillaume, Dreyfus, Gilles, Eker, Armand, Habib, Yakoub, Hugues, Nicolas, Mialhe, Claude, Chavanon, Olivier, Porcu, Paolo, Vanzetto, Gérald, Donzeau-Gouge, Patrick, Didier, Romain, Gommeaux, Bernard, Claudel, Jean-Philippe, Nutrition, obésité et risque thrombotique ( NORT ), Institut National de la Recherche Agronomique ( INRA ) -Aix Marseille Université ( AMU ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Nutrition, obésité et risque thrombotique (NORT), Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, predictive analysis, aortic stenosis, risk score, [ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Abstract

International audience; Transcatheter aortic valve replacement (TAVR) has revolutionized management of high-risk patients with severe aortic stenosis. However, survival and the incidence of severe complications have been assessed in relatively small populations and/or with limited follow-up.; This report details late clinical outcome and its determinants in the FRANCE-2 (FRench Aortic National CoreValve and Edwards) registry.; The FRANCE-2 registry prospectively included all TAVRs performed in France. Follow-up was scheduled at 30 days, at 6 months, and annually from 1 to 5 years. Standardized VARC (Valve Academic Research Consortium) outcome definitions were used.; A total of 4,201 patients were enrolled between January 2010 and January 2012 in 34 centers. Approaches were transarterial (transfemoral 73%, transapical 18%, subclavian 6%, and transaortic or transcarotid 3%) or, in 18% of patients, transapical. Median follow-up was 3.8 years. Vital status was available for 97.2% of patients at 3 years. The 3-year all-cause mortality was 42.0% and cardiovascular mortality was 17.5%. In a multivariate model, predictors of 3-year all-cause mortality were male sex (p < 0.001), low body mass index, (p < 0.001), atrial fibrillation (p < 0.001), dialysis (p < 0.001), New York Heart Association functional class III or IV (p < 0.001), higher logistic EuroSCORE (p

Published
2016

28. Twelve month clinical and angiographic outcome after stenting of unprotected left main coronary artery stenosis with paclitaxel-eluting stents--results of the multicentre FRIEND registry

Author

Carrié, Didier, Eltchaninoff, Hélène, Lefèvre, Thierry, Silvestri, Marc, Levy, Gilles, Maupas, Eric, Brunel, Philippe, Fajadet, Jean, Le Breton, Hervé, Gilard, Martine, Blanchard, Didier, Glatt, Bernard, Renseigné, Non, Department of Cardiology, University Hospital of Rangueil, Faculté de médecine, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Département Electronique et Physique (EPH), Institut Mines-Télécom [Paris] (IMT)-Télécom SudParis (TSP), Services répartis, Architectures, MOdélisation, Validation, Administration des Réseaux (SAMOVAR), Centre National de la Recherche Scientifique (CNRS), Optimisation des régulations physiologiques (ORPHY (EA 4324)), Institut Brestois Santé Agro Matière (IBSAM), and Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)

Subjects
Target lesion, Male, Time Factors, MESH: Registries, medicine.medical_treatment, Coronary Angiography, Severity of Illness Index, chemistry.chemical_compound, MESH: Aged, 80 and over, Prospective Studies, Registries, Angioplasty, Balloon, Coronary, MESH: Treatment Outcome, MESH: Aged, Aged, 80 and over, education.field_of_study, MESH: Middle Aged, Drug-Eluting Stents, Middle Aged, MESH: Angioplasty, Balloon, Coronary, medicine.anatomical_structure, Treatment Outcome, Paclitaxel, Cardiovascular Diseases, Female, Radiology, France, MESH: Cardiovascular Agents, Cardiology and Cardiovascular Medicine, Artery, MESH: Drug-Eluting Stents, Adult, medicine.medical_specialty, Population, Left Main Coronary Artery Stenosis, MESH: Coronary Stenosis, MESH: Severity of Illness Index, medicine, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Humans, cardiovascular diseases, MESH: Paclitaxel, education, Aged, MESH: Humans, business.industry, MESH: Time Factors, Coronary Stenosis, Stent, MESH: Cardiovascular Diseases, MESH: Adult, Cardiovascular Agents, medicine.disease, MESH: Coronary Angiography, MESH: Male, MESH: Prospective Studies, Surgery, MESH: France, Stenosis, chemistry, Conventional PCI, business, MESH: Female
Abstract

International audience; AIMS: To evaluate the angiographic and clinical outcome of patients undergoing paclitaxel-eluting stent (PES) implantation for unprotected left main coronary artery (ULMCA) stenosis in a multicentre, prospective registry. The overall event rate for PCI of ULMCA disease remains higher than in on-label use making additional outcome data and risk-stratification tools for the ULMCA population desirable. METHODS AND RESULTS: A prospective registry included all patients with a significant (> 50%) stenosis in ULMCA disease. In 151 of these patients the target lesion involved the distal bifurcation in 100 patients (66%), which was treated by predominantly using a "provisional T stenting" strategy. In distal ULMCA disease group, 72% had only one stent implantation while 28% had multiple (either 2 or 3) stents implanted. At a median follow-up of 472 +/- 75 days, cardiac death occurred in 3 patients (2%) and major adverse cardiac and cerebrovascular events (MACCE) in 16 patients (10.6%). CONCLUSIONS: In the drug-eluting stent era, paclitaxel eluting stent implantation of ULMCA stenosis provided excellent immediate and mid-term results in this selected population, suggesting that it may be considered as a safe and effective alternative to CABG for selected patients with ULMCA who are treated in institutions performing large numbers of PCI procedures.

Published
2009

32. A Multicenter Randomized Trial Comparing Amphilimus- With Paclitaxel-Eluting Stents in De Novo Native Coronary Artery Lesions

Author

Carrié, Didier, primary, Berland, Jacques, additional, Verheye, Stefan, additional, Hauptmann, Karl Eugen, additional, Vrolix, Mathias, additional, Violini, Roberto, additional, Dibie, Alain, additional, Berti, Sergio, additional, Maupas, Eric, additional, Antoniucci, David, additional, and Schofer, Joachim, additional

Published
2012
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35. Abstract 3346: Percutaneous Treatment Of Unprotected Left Main Coronary Stenoses With Paclitaxel-eluting Stents. Mid-term Results Of A French Prospective Multicenter Study (friend Register)

Author

Carrié, Didier, primary, Eltchaninoff, Hélène, additional, Lefèvre, Thierry, additional, Silvestri, Marc, additional, Levy, Gérard, additional, Maupas, Eric, additional, Brunel, P, additional, Glatt, B, additional, and Blanchard, Didier, additional

Published
2007
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38. Clinical and angiographic outcome of stenting of unprotected left main coronary artery bifurcation narrowing

Author

Carrié, Didier, Maupas, Eric, Hmem, Mohamed, Lhermusier, Thibaut, Elbaz, Meyer, and Puel, Jacques

Abstract

PURPOSE: Improvements in techniques and equipments may result in the wider applicability of percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) stenosis. This report is a prospective study focused on the feasibility, effectiveness and long-term results of stenting for treatment of ULMCA bifurcation lesions. METHODS: From November 2002 to October 2003, 57 consecutive patients were stented with bare metal stents and the technique of kissing balloon followed by T-provisional stenting was applied for ostial left anterior descending, left circumflex or distal left main coronary lesion. RESULTS: Mean age was 69.5±10.7 years. Acute coronary syndrome occurred in 68.4% of patients with a majority of two or three vessel disease (45.10% and 35.30% respectively). GpIIbIIIa inhibitors were used in only 5.8% of cases. Angiographic success was obtained in 100% of patients. Hospital stay was 7.03±2.26 days without major adverse cardiac events. At eight months follow-up, cardiac death was 1.7%, non-fatal myocardial infarction 5.1% and target vessel revascularisation 22.8% including CABG 15.7% and repeated PCI 10.5% with an angiographic restenosis rate of 29.8%. CONCLUSION: In the setting of coronary stenting of the ULMCA stenosis, the use of bare metal stents can no longer be considered contemporary technique and another strategy such as coated stent may be needed.

Published
2005
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39. Predictive value for paravalvular regurgitation of 3-dimensional anatomic aortic annulus shape assessed by multidetector computed tomography post-transcatheter aortic valve replacement.

Author

Ciobotaru V, Maupas E, Dürrleman N, Boulenc JM, Borton A, Pujadas-Berthault P, Rioux P, and Maubon A

Subjects
Aged, Aged, 80 and over, Female, Humans, Imaging, Three-Dimensional, Male, Predictive Value of Tests, Prosthesis Design, Prosthesis Fitting, Sensitivity and Specificity, Severity of Illness Index, Treatment Outcome, Aortic Valve Insufficiency diagnosis, Aortic Valve Insufficiency etiology, Aortic Valve Stenosis surgery, Multidetector Computed Tomography methods, Transcatheter Aortic Valve Replacement adverse effects
Abstract

Aims: Paravalvular regurgitation (PAR) remains a serious complication after trans-catheter aortic valve replacement (TAVR). Multidetector computed tomography (MDCT)-based measurements of the aortic basal virtual ring (BVR) are considered the gold standard for trans-catheter heart valve (THV) sizing. However, the real anatomic aortic annulus is a 3-dimensional structure. To compare measurement of 3D-anatomic annulus with BVR and secondly to assess independent predictive parameters that may impact on PAR > mild post-TAVR (PAR+)., Methods and Results: MDCT was performed in 92 patients before and after balloon or self-expandable TAVR. 3D-AA shape was obtained point by point following the semilunar attachment of aortic cusps (Osirix-MD 2.8.2). 3D-oversizing index (nominal THV area/3D-AA area - 1) × 100 was calculated as well as 2D-oversizing index using BVR area instead of 3D-AA area. PAR was quantified by planimetry of vena-contracta in transthoracic echocardiography short-axis view. Valvular calcium volume and annulus calcium area were measured using Hounsfield-intensity detection. ROC curves and logistic regression for PAR(+) were performed. BVR area overall underestimated 3D-AA area by 19 ± 9% (P< 0.001), significantly more in PAR(+) (26 ± 7%) vs. PAR(-) (17 ± 9%, P< 0.001). 3D-oversizing index had greater predictive value for PAR > mild (area under the curve, AUC = 0.88) with 88% sensibility (Se) and 82% specificity (Sp) than 2D-oversizing index (AUC = 0.68) with 84% Se, but only 41% Sp (P< 0.0001). Also, valvular calcium volume and annulus calcium area were less predictors for PAR > mild (AUC = 0.68, respectively, AUC = 0.75, P = 0.002). In a multivariate analysis, only 3D-oversizing index showed an independent value for PAR > mild (OR = 18.6, P< 0.001)., Conclusion: Basal ring CT measurement significantly underestimated the real 3D-anatomic aortic annulus area. This may impact on THV sizing and PAR incidence. 3D-oversizing index is the most predictive factor for PAR > mild., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.)

Published
2016
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40. Radiofrequency ablation of an atrial tachycardia emanating from the non-coronary aortic Cusp guided by an electroanatomic navigation system.

Author

Bortone A and Maupas E

Abstract

We report on an atrial tachycardia (AT), emanating from the non-coronary (NC) aortic cusp, ablated with the aid of an electro-anatomical navigation system. In this setting, the electrocardiographic, electrophysiologic (EP), anatomical, and ablative considerations are discussed.Although NC aortic cusp focal ATs are an uncommon EP finding, their ablation is effective and safe, especially from an atrio-ventricular (AV) conductive point of view. This origin of AT must be invoked and systematically disclosed when a peri-AV nodal AT origin is suspected, in order to avoid a potentially harmful energy application at the vicinity of the AV conductive tissue.

Published
2010

41. Clinical and angiographic outcome of paclitaxel-eluting stent implantation for unprotected left main coronary artery bifurcation narrowing.

Author

Carrié D, Lhermusier T, Hmem M, Maupas E, Elbaz M, and Puel J

Abstract

Aims: This study was designed to compare the clinical and angiographic outcomes of paclitaxel-eluting stent (PES) and bare metal stent (BMS) implantation for unprotected left main coronary artery (LMCA) bifurcation narrowing., Methods and Results: From November 2003 to December 2004, the technique of kissing balloon followed by T provisional stenting was applied for distal left main coronary lesion in 49 consecutive patients with PES stents. Data from this group were compared to those from 57 patients treated with BMS during the previous year. The procedural success rate was 100% for both groups. There were no incidents of death, stent thrombosis, Q-wave myocardial infarction (MI), or emergent bypass surgery during hospitalization in either group. Despite less acute gain (2.18+/-0.53 mm vs. 2.45+/-0.47 mm p= 0.078) in the PES group, PES patients showed a lower late lumen loss and a lower 8-month angiographic restenosis rate (6.1% vs. 35.1% p<0.0001) versus the BMS group. At 10 months, the rate of freedom from death,MI, and target lesion revascularization was 95.9+/-2.8% in the PES group and 66.1+/-6.3% in the BMS group (p<0.0001)., Conclusion: Paclitaxel-eluting stent implantation for unprotected LMCA bifurcation narrowing appears safe with regard to acute and midterm complications and is more effective in preventing restenosis compared to BMS implantation.

Published
2006

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