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211 results on '"Mazzariol S"'

4. Nothing is as it seems: genetic analyses on stranded fin whales unveil the presence of a fin-blue whale hybrid in the Mediterranean Sea (Balaenopteridae)

Author

Fioravanti, T., primary, Maio, N., additional, Latini, L., additional, Splendiani, A., additional, Guarino, F. M., additional, Mezzasalma, M., additional, Petraccioli, A., additional, Cozzi, B., additional, Mazzariol, S., additional, Centelleghe, C., additional, Sciancalepore, G., additional, Pietroluongo, G., additional, Podestà, M., additional, and Caputo Barucchi, V., additional

Published
2022
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7. WILDLIFE POISONING IN EMILIA ROMAGNA REGION (ITALY): A 10-YEARS-SURVEY

Author

Rubini Silva, Faggionato E., Biancardi A., Merialdi G., Merenda M., Massi P., Frasnelli M., Garbarino C. A., Gelmini L., Luppi A., Cotti C., Musto C., Delogu M., Talarico A., Gaudio R. M., Frisoni P., Strano Rossi S., Locatelli C. A., Mazzariol S., and Rubini Silva, Faggionato E., Biancardi A., Merialdi G., Merenda M., Massi P., Frasnelli M., Garbarino C.A., Gelmini L., Luppi A., Cotti C., Musto C., Delogu M., Talarico A., Gaudio R.M., Frisoni P., Strano Rossi S., Locatelli C.A., Mazzariol S.

Subjects
Wildlife, poisoning, Emilia Romagna
Published
2019

9. Measles, immune amnesia, and cetaceans

Author

Di Guardo, G and Mazzariol, S

Subjects
Measles virus, Viral immunopathogenesis, Measles, Measles virus, Cetacean morbillivirus, Comparative immunopathology, Viral immunopathogenesis, Animal models of human disease, Comparative immunopathology, Animal models of human disease, Cetacean morbillivirus, Measles
Published
2019

12. Guest Editorial: Comparative Immunology of Marine Mammals

Author

Di Guardo, G, Criscitiello, Mf, Sierra, E, and Mazzariol, S

Subjects
Immunotoxic contaminants, Cetaceans, Comparative immunology, innate immunity, acquired Immunity, host-pathogen interaction, Immunotoxic contaminants, marine mammals, Cetaceans, Pinnipeds, Comparative immunology, acquired Immunity, host-pathogen interaction, Pinnipeds, marine mammals, innate immunity
Published
2019

14. Evolutionary evidence for multi-host transmission of cetacean morbillivirus

Author

Jo, WK, Kruppa, J, Habierski, A, van de Bildt, Marco, Mazzariol, S, Di Guardo, G, Siebert, U, Kuiken, Thijs, Jung, K, Osterhaus, A, Ludlow, M, and Virology

Subjects
Seals, Earless, Dolphins, lcsh:QR1-502, High-Throughput Nucleotide Sequencing, Bayes Theorem, Genome, Viral, lcsh:Microbiology, Article, lcsh:Infectious and parasitic diseases, Evolution, Molecular, Phylogeography, Morbillivirus, Signaling Lymphocytic Activation Molecule Family Member 1, Mediterranean Sea, Animals, Receptors, Virus, lcsh:RC109-216, Cetacea, North Sea, Morbillivirus Infections
Abstract

Cetacean morbillivirus (CeMV) has emerged as the pathogen that poses the greatest risk of triggering epizootics in cetacean populations worldwide, and has a high propensity for interspecies transmission, including sporadic infection of seals. In this study, we investigated the evolutionary history of CeMV by deep sequencing wild-type viruses from tissue samples representing cetacean species with different spatiotemporal origins. Bayesian phylogeographic analysis generated an estimated evolutionary rate of 2.34 × 10−4 nucleotide substitutions/site/year and showed that CeMV evolutionary dynamics are neither host-restricted nor location-restricted. Moreover, the dolphin morbillivirus strain of CeMV has undergone purifying selection without evidence of species-specific mutations. Cell-to-cell fusion and growth kinetics assays demonstrated that CeMV can use both dolphin and seal CD150 as a cellular receptor. Thus, it appears that CeMV can readily spread among multiple cetacean populations and may pose an additional spillover risk to seals.

Published
2018

18. Novel dolphin morbillivirus (DMV) outbreak among Mediterranean striped dolphins Stenella coeruleoalba in Italian waters

Author

Pautasso, A, primary, Iulini, B, additional, Grattarola, C, additional, Giorda, F, additional, Goria, M, additional, Peletto, S, additional, Masoero, L, additional, Mignone, W, additional, Varello, K, additional, Petrella, A, additional, Carbone, A, additional, Pintore, A, additional, Denurra, D, additional, Scholl, F, additional, Cersini, A, additional, Puleio, R, additional, Purpari, G, additional, Lucifora, G, additional, Fusco, G, additional, Di Guardo, G, additional, Mazzariol, S, additional, and Casalone, C, additional

Published
2019
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19. Evolutionary evidence for multi-host transmission of cetacean morbillivirus

Author

Jo, W.K. (Wendy K.), Kruppa, J. (Jochen), Habierski, A. (André), Bildt, M.W.G. (Marco) van de, Mazzariol, S. (Sandro), di Guardo, G. (Giovanni), Siebert, U. (Ursula), Kuiken, T. (Thijs), Jung, K. (Klaus), Osterhaus, A. (Albert), Ludlow, M. (Martin), Jo, W.K. (Wendy K.), Kruppa, J. (Jochen), Habierski, A. (André), Bildt, M.W.G. (Marco) van de, Mazzariol, S. (Sandro), di Guardo, G. (Giovanni), Siebert, U. (Ursula), Kuiken, T. (Thijs), Jung, K. (Klaus), Osterhaus, A. (Albert), and Ludlow, M. (Martin)

Abstract

Cetacean morbillivirus (CeMV) has emerged as the pathogen that poses the greatest risk of triggering epizootics in cetacean populations worldwide, and has a high propensity for interspecies transmission, including sporadic infection of seals. In this study, we investigated the evolutionary history of CeMV by deep sequencing wild-type viruses from tissue samples representing cetacean species with different spatiotemporal origins. Bayesian phylogeographic analysis generated an estimated evolutionary rate of 2.34 × 10−4 nucleotide substitutions/site/year and showed that CeMV evolutionary dynamics are neither host-restricted nor location-restricted. Moreover, the dolphin morbillivirus strain of CeMV has undergone purifying selection without evidence of species-specific mutations. Cell-to-cell fusion and growth kinetics assays demonstrated that CeMV can use both dolphin and seal CD150 as a cellular receptor. Thus, it appears that CeMV can readily spread among multiple cetacean populations and may pose an additional spillover risk to seals.

Published
2018
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20. Postmortem Findings in Cetaceans Found Stranded in the Pelagos Sanctuary, Italy, 2007-2014

Author

Giorda F, Ballardini M, DI GUARDO, Giovanni, Pintore, Md, Grattarola, C, Iulini, B, Mignone, W, Goria, M, Serracca, L, Varello, K, Dondo, A, Acutis, Pl, Garibaldi, F, Scaglione, Fe, Gustinelli, A, Mazzariol, S, DI FRANCESCO, Cristina Esmeralda, Tittarelli, C, Casalone, C, and Pautasso, A.

Subjects
disease, Cetaceans, Italy, necropsy, strandings, Mediterranean Sea
Published
2017

22. Clinico-pathological findings in a striped dolphin (Stenella coeruleoalba) affected by rhabdomyolysis and myoglobinuric nephrosis (capture myopathy)

Author

Bonsembiante, F., Centelleghe, C., Rossi, G., Giglio, S., Madeo, E., Gelain, M.E., Mazzariol, S., Bonsembiante, F., Centelleghe, C., Rossi, G., Giglio, S., Madeo, E., Gelain, M.E., and Mazzariol, S.

Abstract

A striped dolphin (Stenella coeruleoalba) calf stranded alive because of a Salter-Harris fracture type 1 of a caudal vertebra and remained in a provisional rehabilitation facility for 3 days where the fracture stabilization was attempted, but he died the day after bandaging. Serum and urine samples were collected during hospitalization (days 1, 2 and 3 serum and day 2 urine). Serum analysis showed increased urea, alanine transaminase, aspartate transaminase, and serum amyloid A values, while creatinine was below the lower limit. Urine analysis showed urinary protein-to-creatinine ratio of 5.3 with glomerular proteinuria. Postmortem analyses demonstrated a severe rhabdomyolysis and myoglobinuric nephrosis, suggestive of capture myopathy syndrome. We report, for the first time, the clinico-pathological changes during this condition in a striped dolphin.

Published
2017

25. Candidate gene molecular markers as tools for analyzing genetic susceptibility to morbillivirus infection in stranded Cetaceans

Author

Stejskalova, K., primary, Bayerova, Z., additional, Futas, J., additional, Hrazdilova, K., additional, Klumplerova, M., additional, Oppelt, J., additional, Splichalova, P., additional, Di Guardo, G., additional, Mazzariol, S., additional, Di Francesco, C. E., additional, Di Francesco, G., additional, Terracciano, G., additional, Paiu, R.-M., additional, Ursache, T. D., additional, Modry, D., additional, and Horin, P., additional

Published
2017
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26. Localization of Viral Antigens and Brain Ultrastructural Findings in Striped Dolphins (Stenella coeruleoalba) with ‘Brain-Only’ Dolphin morbillivirus Infection

Author

Di Guardo, G., primary, Giacominelli-Stuffler, R., additional, Baffoni, M., additional, Pietroluongo, G., additional, Di Francesco, C.E., additional, Dufrusine, B., additional, Dainese, E., additional, Cocumelli, C., additional, Eleni, C., additional, Lucà, R., additional, Roperto, F.P., additional, Roperto, S., additional, Casalone, C., additional, Di Francesco, G., additional, Leonardi, L., additional, Centelleghe, C., additional, and Mazzariol, S., additional

Published
2017
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28. Di Guardo G., Pennelli M., Marcer F., Mazzariol S. (2015). Contributo in volume (Capitolo). Principali patologie dei Cetacei. In: Mazzariol S., Cozzi B., Centelleghe C. Spiaggiamento dei Cetacei. Manuale di gestione, pp. 99-131. Massimo Valdina Editore, the CoffeeHouse art&media, Milano, ISBN 979-888817613-0 978888176130. Di Guardo G., Pennelli M., Marcer F., Mazzariol S. (2015). Contributo in volume (Capitolo). Principali patologie dei Cetacei. In: Mazzariol S., Cozzi B., Centelleghe C. Spiaggiamento dei Cetacei. Manuale di gestione, pp. 99-131. Massimo Valdina Editore, the CoffeeHouse art&media, Milano, ISBN 979-888817613-0 978888176130. Principali patologie dei Cetacei

Author

DI GUARDO, Giovanni, Pennelli, M, Marcer, F, and Mazzariol, S.

Subjects
Cetaceans, Pathology, Cetacean strandings
Published
2015

30. Cetacean morbillivirus: current knowledge and future directions (Review)

Author

Van Bressem, Mf, Duignan, Pj, Banyard, A, Barbieri, M, Colegrove, Km, De Guise, S, DI GUARDO, Giovanni, Dobson, A, Domingo, M, Fauquier, D, Fernandez, A, Goldstein, T, Grenfell, B, Groch, Kr, Gulland, F, Jensen, Ba, Jepson, Pd, Hall, A, Kuiken, T, Mazzariol, S, Morris, Se, Nielsen, O, Raga, Ja, Rowles, Tk, Saliki, J, Sierra, E, Stephens, N, Stone, B, Tomo, I, Wang, J, Waltzek, T, and Wellehan, Jf

Subjects
Cetacean Morbillivirus, Morbillivirus, Aquatic mammals, Cetaceans, Pinnipeds, Review, Cetaceans, Morbillivirus, Aquatic mammals, Cetacean Morbillivirus, Review, Pinnipeds
Published
2014

32. Post-mortem findings in cetaceans stranded on the Italian coastline

Author

Mazzariol S., Di Guardo G., Marruchella G., Butti C., Cozzi B., Kennedy S., Fichtel L., Furlati S., Zucca P., Iorio R., Castagnaro M., BENAZZI, CINZIA, Mazzariol S., Di Guardo G., Marruchella G., Butti C., Cozzi B., Kennedy S., BENAZZI C., Fichtel L., Furlati S., Zucca P., Iorio R., and Castagnaro M.

Subjects
DOLPHINS, human activities
Abstract

Stranded cetaceans offer a unique opportunity for collecting data on the health status of dolphins and whale free-living populations. We report the post-mortem findings observed in18 odontocetes found stranded between 2000 and 2005 on the Italian coastline. Pneumonia was one of the most encountered lesion. additional findings were nephritis, epatitis and Pholeter gastrophilus-associasted gastritis. In a few cases, putative zoonotic agents, such as Vibrio alginolyticus, were isolated from these stranded dolphins.

Published
2006

39. Italy. Progress report on cetacean research, January to December 2010, with statistical data for the calendar year 2010

Author

Filidei, E., Alessi, J., Azzolin, M., Bacchetta, M., Bedocchi, D., Bellingeri, M., Bittau, L., Castelli, A., Clò, S., Cozzi, B., DI GUARDO, G., Fiori, C., Fossa, F., Fossi, MARIA CRISTINA, Marsili, Letizia, Fozzi, A., Gattoni, A. M., Giurisato, M., Lauriano, G., Magnone, F., Marsili, L., Mazzariol, S., Mignone, W., Moulins, A., Nuti, S., ORSI RELINI, L., Papale, E., Pavan, G., Podestà, M., Pulcini, M., Rosso, M., Rutigliano, R., Tempesta, M., P. TEPSICH, C. TITTARELLI, Tringali, M., Wurtz, M., Zardin, F., and Fortuna, C. M.

Published
2011

41. Italy. Progress report on cetacean research, January 2009 to December 2009, with statistical data for the calendar year 2008

Author

Fortuna, C. M., Filidei, E., Aissi, M., Arcangeli, A., Bedocchi, D., Bellingeri, M., Bortolotto, A., Celona, A., Cozzi, B., DI GUARDO, G., DIAZ LOPEZ, B., Fossa, F., Fossi, M. C., Marsili, L., Mazzariol, S., Mazzola, A., Moulins, A., Nuti, S., Pace, D. S., Pavan, G., Pennelli, M., Podestà, M., Politi, E., Serena, F., Rosso, M., Sala, A., Tepsich, P., Wurtz, M., and Tunesi, L.

Published
2010

43. Progress report on cetacean research, January to December 2010, with statistical data for the calendar year 2010

Author

Filidei, E. Jr., Alessi, J., Arcangeli, A., Azzolin, M., Bacchetta, M., Bedocchi, D., Bellingeri, M., Bittau, L., Castelli, A., Clò, S., Cozzi, B., Diaz Lopez, B., Di Guardo, G., Fiori, C., Fossa, F., Fossi, M. C., Fozzi, A., Gattoni, A. M., Giurisato, M., Gnone, G., La Manna, G., Lauriano, G., Magnone, F., Marini, L., Marsili, L., Mazzariol, S., Mignone, W., Moulins, A., Nuti, S., Orsi Relini, L., Papale, E., Pavan, G., Podestà, M., Pulcini, M., Rosso, M., Rutigliano, R., Tempesta, M., Tepsich, P., Tittarelli, C., Tringali, M., Wurtz, M., Zardin, F., and Fortuna, C. M.

Published
2010

45. Phocine distemper Virus: Current knowledge and future directions

Author

Duignan, P., Van Bressem, M.-F. (Marie-Françoise), Baker, J.D. (Jason), Barbieri, M. (Michelle), Colegrove, K.M. (Kathleen M), De Guise, S. (Sylvain), Swart, R.L. (Rik) de, di Guardo, G. (Giovanni), Dobson, A.P. (Andrew), Duprex, W.P. (Paul), Early, G. (Greg), Fauquier, D. (Deborah), Goldstein, T. (Tracey), Goodman, S.J. (Simon J.), Grenfell, B.T. (Bryan), Groch, K.R. (Kátia R.), Gulland, F. (Frances), Hall, A. (Ailsa), Jensen, B.A. (Brenda A.), Lamy, K. (Karina), Matassa, K. (Keith), Mazzariol, S. (Sandro), Morris, S.E. (Sinead E.), Nielsen, O. (Ole), Rotstein, D. (David), Rowles, T.K. (Teresa K), Saliki, J. (Jeremy), Siebert, U. (Ursula), Waltzek, T. (Thomas), Wellehan, J.F.X. (James F. X.), Duignan, P., Van Bressem, M.-F. (Marie-Françoise), Baker, J.D. (Jason), Barbieri, M. (Michelle), Colegrove, K.M. (Kathleen M), De Guise, S. (Sylvain), Swart, R.L. (Rik) de, di Guardo, G. (Giovanni), Dobson, A.P. (Andrew), Duprex, W.P. (Paul), Early, G. (Greg), Fauquier, D. (Deborah), Goldstein, T. (Tracey), Goodman, S.J. (Simon J.), Grenfell, B.T. (Bryan), Groch, K.R. (Kátia R.), Gulland, F. (Frances), Hall, A. (Ailsa), Jensen, B.A. (Brenda A.), Lamy, K. (Karina), Matassa, K. (Keith), Mazzariol, S. (Sandro), Morris, S.E. (Sinead E.), Nielsen, O. (Ole), Rotstein, D. (David), Rowles, T.K. (Teresa K), Saliki, J. (Jeremy), Siebert, U. (Ursula), Waltzek, T. (Thomas), and Wellehan, J.F.X. (James F. X.)

Abstract

Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years.

Published
2014
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46. Cetacean morbillivirus: Current knowledge and future directions

Author

Van Bressem, M-F, Duignan, P., Banyard, A., Barbieri, M., Colegrove, K., De Guise, S., Di Guardo, G., Dobson, A., Domingo, M., Fauquier, D., Fernandez, A., Goldstein, T., Grenfell, B., Groch, K., Gulland, F., Jensen, B., Jepson, P., Hall, A., Kuiken, T., Mazzariol, S., Morris, S., Nielsen, O., Raga, J., Rowles, T., Saliki, J., Sierra, E., Stephens, N., Stone, B., Tomo, I., Wang, J., Waltzek, T., Wellehan, J., Van Bressem, M-F, Duignan, P., Banyard, A., Barbieri, M., Colegrove, K., De Guise, S., Di Guardo, G., Dobson, A., Domingo, M., Fauquier, D., Fernandez, A., Goldstein, T., Grenfell, B., Groch, K., Gulland, F., Jensen, B., Jepson, P., Hall, A., Kuiken, T., Mazzariol, S., Morris, S., Nielsen, O., Raga, J., Rowles, T., Saliki, J., Sierra, E., Stephens, N., Stone, B., Tomo, I., Wang, J., Waltzek, T., and Wellehan, J.

Abstract

We review the molecular and epidemiological characteristics of cetacean morbillivirus (CeMV) and the diagnosis and pathogenesis of associated disease, with six different strains detected in cetaceans worldwide. CeMV has caused epidemics with high mortality in odontocetes in Europe, the USAand Australia. It represents a distinct species within the Morbillivirusgenus. Although most CeMV strains are phylogenetically closely related, recent data indicate that morbilliviruses recovered from Indo-Pacific bottlenose dolphins (Tursiops aduncus), from Western Australia, and a Guiana dolphin (Sotalia guianensis), from Brazil, are divergent. The signaling lymphocyte activation molecule (SLAM) cell receptor for CeMV has been characterized in cetaceans. It shares higher amino acid identity with the ruminant SLAM than with the receptors of carnivores or humans, reflecting the evolutionary history of these mammalian taxa. In Delphinidae, three amino acid substitutions may result in a higher affinity for the virus. Infection is diagnosed by histology, immunohistochemistry, virus isolation, RT-PCR, and serology. Classical CeMV-associated lesions include bronchointerstitial pneumonia, encephalitis, syncytia, and lymphoid depletion associated with immunosuppression. Cetaceans that survive the acute disease may develop fatal secondary infections and chronic encephalitis. Endemicallyinfected, gregarious odontocetes probably serve as reservoirs and vectors. Transmission likely occurs through the inhalation of aerosolized virus but mother to fetus transmission was also reported.

Published
2014

47. Italy. Progress report on cetacean research, January 2008 to December 2008, with statistical data for the calendar year 2007

Author

Fortuna, C., Agazzi, S., Arcangeli, A., Bedocchi, D., Borsani, J., Bortolotto, A., Clò, S., Cozzi, B., DI GUARDO, G., DIAZ LOPEZ, B., Fossi, MARIA CRISTINA, Galante, I., Gattoni, A. M., Giurisato, M., Marsili, Letizia, Mazzariol, S., Mazzola, A., Moulins, A., Natoli, A., Nuti, S., Pavan, G., Podestà, M., Proietto, U., Pulcini, M., Puppini, A., Rosso, M., Tepsich, P., Würtz, M., and Canese, S.

Published
2009

49. Italy. Progress report on cetacean research, January 2007 to December 2007, with statistical data for the calendar year 2006

Author

Fortuna, C. M., Agazzi, S., Arcangeli, A., Bedocchi, D., Blasi, M. F., Borsani, F., Bortolotto, A., Buffa, G., Cozzi, B., DI GUARDO, G., DÍAZ LÓPEZ, B., Fattorosi, L., Fossi, MARIA CRISTINA, Gnone, G., Marsili, Letizia, Mazzariol, S., Moulins, A., Natoli, A., Nuti, S., Pavan, G., Pelusi, P., Podestà, M., Rosso, M., Serena, F., Tepsich, P., and Tunesi, L.

Published
2008

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