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3. A proposed mathematical model to help preoperative planning between RIRS and MiniPerc for renal stones between 10 and 20 mm using holmium:Yag laser (Cyber Ho): the stone management according to size-hardness (SMASH) score

Author

Perri, D., Mazzoleni, F., Besana, U., Pacchetti, A., Morini, E., Calandriello, M., Pastore, A. L., Romero-Otero, J., Bruyere, F., Sighinolfi, M. C., Rocco, B., Micali, S., Gozen, A. S., Liatsikos, E., Roche, J. B., and Bozzini, G.

Published
2024
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6. Integrative multi-omics analysis enables a comprehensive characterization of prostate cancer and unveils metastasis-associated candidate biomarkers

Author

Villa, M., primary, Cazzaniga, G., additional, Bolognesi, M., additional, Crippa, V., additional, Malighetti, F., additional, Aroldi, A., additional, Perri, D., additional, Mazzoleni, F., additional, Bozzini, G., additional, Pagni, F., additional, Piazza, R., additional, Mologni, L., additional, and Ramazzotti, D., additional

Published
2024
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9. European Guideline Robin Sequence An Initiative From the European Reference Network for Rare Craniofacial Anomalies and Ear, Nose and Throat Disorders (ERN-CRANIO)

Author

Abadie, V., Bohorquez, D., Bulstrode, N. W., Davies, Gareth, Hakelius, Malin, Ong, J., Mathijssen, I. M. J., Matos, E., Mazzoleni, F., van der Molen, A. Mink, Muradin, M., Neovius, E., Piacentile, K., Redondo, M., Vuola, P., Wolvius, E. B., Reinert, Siegmar, Murray, Dylan, Peterson, Petra, Hens, Greet, Schachner, P., Sivertsen, A., Irvine, W. F. E., Welling-van Overveld, L. F. J., van Breugel, M., van Schalkwijk, K., Verhey, E., Khan, A., Baillie, L., Bishop, N., Hillyar, C. R. T., Koudstaal, M. J., van de lande, L., Nibber, A., Panciewicz, N., Ramjeeawan, A., Bouter, A., El Ghoul, K., Logjes, B., van der Plas, P., Kats, J., Weissbach, E., van Veen-van der Hoek, M., Bittermann, A. J. N., van den Boogaard, M-JH., Coenraad, S., Dulfer, K., Joosten, K., Lachmeijer, A. M. A., Muradin, M. S. M., Peters, N. C. J., Pleumeekers, M., de Veye, H. Swanenburg, Abadie, V., Bohorquez, D., Bulstrode, N. W., Davies, Gareth, Hakelius, Malin, Ong, J., Mathijssen, I. M. J., Matos, E., Mazzoleni, F., van der Molen, A. Mink, Muradin, M., Neovius, E., Piacentile, K., Redondo, M., Vuola, P., Wolvius, E. B., Reinert, Siegmar, Murray, Dylan, Peterson, Petra, Hens, Greet, Schachner, P., Sivertsen, A., Irvine, W. F. E., Welling-van Overveld, L. F. J., van Breugel, M., van Schalkwijk, K., Verhey, E., Khan, A., Baillie, L., Bishop, N., Hillyar, C. R. T., Koudstaal, M. J., van de lande, L., Nibber, A., Panciewicz, N., Ramjeeawan, A., Bouter, A., El Ghoul, K., Logjes, B., van der Plas, P., Kats, J., Weissbach, E., van Veen-van der Hoek, M., Bittermann, A. J. N., van den Boogaard, M-JH., Coenraad, S., Dulfer, K., Joosten, K., Lachmeijer, A. M. A., Muradin, M. S. M., Peters, N. C. J., Pleumeekers, M., and de Veye, H. Swanenburg

Abstract

A European guideline on Robin Sequence was developed within the European Reference Network for rare and/ or complex craniofacial anomalies and ear, nose, and throat disorders. The guideline provides an overview of optimal care provisions for patients with Robin Sequence and recommendations for the improvement of care.

Published
2024
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10. Maxillary Hypoplasia and Non-Invasive Ventilation: Literature Review and Proposed New Treatment Protocol

Author

Meazzini, M, Moretti, M, Canzi, G, Sozzi, D, Novelli, G, Mazzoleni, F, Meazzini, Maria Costanza, Moretti, Mattia, Canzi, Gabriele, Sozzi, Davide, Novelli, Giorgio, Mazzoleni, Fabio, Meazzini, M, Moretti, M, Canzi, G, Sozzi, D, Novelli, G, Mazzoleni, F, Meazzini, Maria Costanza, Moretti, Mattia, Canzi, Gabriele, Sozzi, Davide, Novelli, Giorgio, and Mazzoleni, Fabio

Abstract

The impact of non-invasive ventilation (NIV) on pediatric maxillary growth is a subject of ongoing research considering its increased use in the pediatric population due to technological advancements and broader indications. This review examines the existing literature, encompassing original articles, case reports, and reviews, to evaluate the effects of NIV on maxillary development and explore potential treatment options. Although the majority of studies agree on the adverse effects of prolonged NIV on maxillary development, techniques for its correction remain understudied. Introducing a novel treatment protocol, we addressed the challenge of correcting severe midfacial hypoplasia in a child with congenital central hypoventilation syndrome (CCHS) undergoing NIV therapy, thus sidestepping the necessity for osteotomies. This proposed protocol holds promise in correcting the adverse impact of NIV on maxillary growth, emphasizing the need for further exploration into innovative treatment modalities.

Published
2024

11. Long-term mandibular growth in patients with airway obstruction treated with mandibular distraction

Author

Meazzini, M, Piza, A, Novelli, G, Sozzi, D, de Ponti, E, Mazzoleni, F, Meazzini, Maria Costanza, Piza, Alejandro, Giorgio, Novelli, Sozzi, Davide, de Ponti, Elena, Mazzoleni, Fabio, Meazzini, M, Piza, A, Novelli, G, Sozzi, D, de Ponti, E, Mazzoleni, F, Meazzini, Maria Costanza, Piza, Alejandro, Giorgio, Novelli, Sozzi, Davide, de Ponti, Elena, and Mazzoleni, Fabio

Abstract

Congenital craniofacial malformations play an important role in upper airway obstruction. One of the main causes is mandibular hypoplasia which is present in the pierre robin sequence. Mandibular distraction osteogenesis (MDO) is one of the most commonly used treatments for the resolution of upper airway obstruction in patients that do not respond to a conservative treatment. We performed a long term follow up of syndromic and non-syndromic patients with pierre robin sequence where the lateral xrays were studied before surgery (T1), after MDO (T2) and long-term follow-up (T3, at least 5 years). Possible complications of the surgery were also studied through panoramic x-rays and clinical controls. The results evidenced an increase of mandibular length comparing T1-T2 and a good stability during the long-term follow-up. The Sd patients presented smaller mandible dimensions. We had not found any complications during the follow-up. The scars outcomes are modest, but none of the patients requested a surgical correction. Mandibular distraction osteogenesis is a treatment to be considered in patients with upper airway obstruction that do not respond to conservative treatments. The results of the surgery are stable and the complications in experienced hands are low.

Published
2024

12. Complications according to intrathoracic versus extrathoracic venous access for cardiac device implantation: results from the PLACE (Planning Lead Access for Cardiac Electrostimulation) study

Author

Dell'era, G, primary, Ghiglieno, C, additional, Palmisano, P, additional, Floris, R, additional, Pimpini, L, additional, Coluccia, G, additional, Fais, L M, additional, Colombo, C, additional, Malacrida, M, additional, D'amico, A, additional, Mazzoleni, F, additional, Antonicelli, R, additional, Delogu, G, additional, Accogli, M, additional, and Patti, G, additional

Published
2023
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14. Final performances of the X-ray Mirrors of the JET-X telescope

Author

Poretti, E., Campana, S., Citterio, O., Conconi, P., Ghigo, M., Mazzoleni, F., Tagliaferri, G., Cusumano, G., La Rosa, G., Brauninger, W., Burkert, W., Castelli, C. M., and Willingale, R.

Subjects
Astrophysics
Abstract

The Joint European Telesscope (JET-X) is one of the core scientific instruments of the SPECTRUM-X-Gamma mission. JET-X was designed to study X-ray emissions in the band 0.3-10 KeV. Its angular resolution is better than 20 arcsec; the values of the effective areas are 161 cm2 at 1.5 KeV and 69 cm2 at 8 Kev (for one telescope). The value of the HEW circle in function of the off-axis angle is presented; it is found to be below 20 arcsec at 1.5 Kev and around 23 arcsec at 8 KeV up to an off-axis angle of 12 arcmin., Comment: 2 pages, 1 ps figure. To be published in the Proceedings of the IAU Symposium 188 THE HOT UNIVERSE, held in Kyoto (August 26-30, 1997) in occasion of the XXIII IAU General Assembly

Published
1997

16. Effectiveness of Le Fort III osteotomy on obstructive sleep apnea syndrome in craniofacial synostosis

Author

Sergio, M, Mazzoleni, F, Meazzini, M, Mattia, M, Canzi, G, Sozzi, D, Novelli, G, Mirabella Sergio, Mazzoleni Fabio, Meazzini Maria Costanza, Moretti mattia, Canzi Gabriele, Davide Sozzi, Novelli Giorgio, Sergio, M, Mazzoleni, F, Meazzini, M, Mattia, M, Canzi, G, Sozzi, D, Novelli, G, Mirabella Sergio, Mazzoleni Fabio, Meazzini Maria Costanza, Moretti mattia, Canzi Gabriele, Davide Sozzi, and Novelli Giorgio

Published
2023

17. Towards a common language in neurosurgical outcome evaluation: the NEON (NEurosurgical Outcome Network) proposal

Author

Ferroli, P, Schiavolin, S, Mariniello, A, Acerbi, F, Restelli, F, Schiariti, M, LA Corte, E, Falco, J, Levi, V, Dimeco, F, Assietti, R, Bongetta, D, Colombo, E, Bellocchi, S, Sangiorgi, S, Bistazzoni, S, Polosa, M, Orru, M, Spena, G, Bernucci, C, Sicignano, A, Fanti, A, Brembilla, C, Resmini, B, Costi, E, Cenzato, M, Talamonti, G, Bottini, G, Scarpa, P, Bollani, A, Querzola, M, Palmas, G, DE Gonda, F, Bosio, L, Egidi, M, Tardivo, V, Fioravanti, A, Subacchi, S, Fontanella, M, Biroli, A, Cereda, C, Panciani, P, Bergomi, R, Pertichetti, M, Tancioni, F, Bona, A, Tartara, F, Fornari, M, Pessina, F, Lasio, G, Cardia, A, Servadei, F, Riva, M, Casarotti, A, Giussani, C, Fiori, L, Mazzoleni, F, Vaiani, S, Carrabba, G, DI Cristofori, A, Sganzerla, E, Vimercati, A, Isella, V, Mauri, I, Incerti, M, Sicuri, G, Miramonti, V, Stefini, R, Spagnoli, D, Piparo, M, Grimod, G, Regazzoni, R, Vismara, D, Mazzeo, L, Monti, E, Franzin, A, Vivaldi, O, Maietti, A, Pini, E, Servello, D, Zekaj, E, DE Michele, S, Locatelli, M, Borsa, S, Grimoldi, N, Caroli, M, Tariciotti, L, Abete-Fornara, G, Vitale, M, Leonardi, M, Broggi, M, Ferroli, Paolo, Schiavolin, Silvia, Mariniello, Arianna, Acerbi, Francesco, Restelli, Francesco, Schiariti, Marco, LA Corte, Emanuele, Falco, Jacopo, Levi, Vincenzo, Dimeco, Francesco, Assietti, Roberto, Bongetta, Daniele, Colombo, Elena V, Bellocchi, Silvio, Sangiorgi, Simone, Bistazzoni, Simona, Polosa, Maria, Orru, Maria I, Spena, Giannantonio, Bernucci, Claudio, Sicignano, Angelo M, Fanti, Andrea, Brembilla, Carlo, Resmini, Bruno, Costi, Emanuele, Cenzato, Marco, Talamonti, Giuseppe, Bottini, Gabriella, Scarpa, Pina, Bollani, Alessandra, Querzola, Matteo, Palmas, Giulio, DE Gonda, Federico, Bosio, Lorenzo, Egidi, Marcello, Tardivo, Valentina, Fioravanti, Antonio, Subacchi, Sara, Fontanella, Marco, Biroli, Antonio, Cereda, Claudio, Panciani, Pier Paolo, Bergomi, Riccardo, Pertichetti, Marta, Tancioni, Flavio, Bona, Alberto, Tartara, Fulvio A, Fornari, Maurizio, Pessina, Federico, Lasio, Giovanni, Cardia, Andrea, Servadei, Franco, Riva, Marco, Casarotti, Alessandra, Giussani, Carlo, Fiori, Leonardo, Mazzoleni, Fabio, Vaiani, Simona, Carrabba, Giorgio, DI Cristofori, Andrea, Sganzerla, Erik P, Vimercati, Alberto, Isella, Valeria, Mauri, Ilaria, Incerti, Michele, Sicuri, Giovanni, Miramonti, Valentina, Stefini, Roberto, Spagnoli, Diego, Piparo, Maurizio, Grimod, Gianluca, Regazzoni, Rossana, Vismara, Daniela, Mazzeo, Lucio, Monti, Emanuele, Franzin, Alberto, Vivaldi, Oscar, Maietti, Alessandra, Pini, Elisa, Servello, Domenico, Zekaj, Edvin, DE Michele, Sara, Locatelli, Marco, Borsa, Stefano, Grimoldi, Nadia, Caroli, Manuela, Tariciotti, Leonardo, Abete-Fornara, Giorgia, Vitale, Mario, Leonardi, Matilde, Broggi, Morgan, Ferroli, P, Schiavolin, S, Mariniello, A, Acerbi, F, Restelli, F, Schiariti, M, LA Corte, E, Falco, J, Levi, V, Dimeco, F, Assietti, R, Bongetta, D, Colombo, E, Bellocchi, S, Sangiorgi, S, Bistazzoni, S, Polosa, M, Orru, M, Spena, G, Bernucci, C, Sicignano, A, Fanti, A, Brembilla, C, Resmini, B, Costi, E, Cenzato, M, Talamonti, G, Bottini, G, Scarpa, P, Bollani, A, Querzola, M, Palmas, G, DE Gonda, F, Bosio, L, Egidi, M, Tardivo, V, Fioravanti, A, Subacchi, S, Fontanella, M, Biroli, A, Cereda, C, Panciani, P, Bergomi, R, Pertichetti, M, Tancioni, F, Bona, A, Tartara, F, Fornari, M, Pessina, F, Lasio, G, Cardia, A, Servadei, F, Riva, M, Casarotti, A, Giussani, C, Fiori, L, Mazzoleni, F, Vaiani, S, Carrabba, G, DI Cristofori, A, Sganzerla, E, Vimercati, A, Isella, V, Mauri, I, Incerti, M, Sicuri, G, Miramonti, V, Stefini, R, Spagnoli, D, Piparo, M, Grimod, G, Regazzoni, R, Vismara, D, Mazzeo, L, Monti, E, Franzin, A, Vivaldi, O, Maietti, A, Pini, E, Servello, D, Zekaj, E, DE Michele, S, Locatelli, M, Borsa, S, Grimoldi, N, Caroli, M, Tariciotti, L, Abete-Fornara, G, Vitale, M, Leonardi, M, Broggi, M, Ferroli, Paolo, Schiavolin, Silvia, Mariniello, Arianna, Acerbi, Francesco, Restelli, Francesco, Schiariti, Marco, LA Corte, Emanuele, Falco, Jacopo, Levi, Vincenzo, Dimeco, Francesco, Assietti, Roberto, Bongetta, Daniele, Colombo, Elena V, Bellocchi, Silvio, Sangiorgi, Simone, Bistazzoni, Simona, Polosa, Maria, Orru, Maria I, Spena, Giannantonio, Bernucci, Claudio, Sicignano, Angelo M, Fanti, Andrea, Brembilla, Carlo, Resmini, Bruno, Costi, Emanuele, Cenzato, Marco, Talamonti, Giuseppe, Bottini, Gabriella, Scarpa, Pina, Bollani, Alessandra, Querzola, Matteo, Palmas, Giulio, DE Gonda, Federico, Bosio, Lorenzo, Egidi, Marcello, Tardivo, Valentina, Fioravanti, Antonio, Subacchi, Sara, Fontanella, Marco, Biroli, Antonio, Cereda, Claudio, Panciani, Pier Paolo, Bergomi, Riccardo, Pertichetti, Marta, Tancioni, Flavio, Bona, Alberto, Tartara, Fulvio A, Fornari, Maurizio, Pessina, Federico, Lasio, Giovanni, Cardia, Andrea, Servadei, Franco, Riva, Marco, Casarotti, Alessandra, Giussani, Carlo, Fiori, Leonardo, Mazzoleni, Fabio, Vaiani, Simona, Carrabba, Giorgio, DI Cristofori, Andrea, Sganzerla, Erik P, Vimercati, Alberto, Isella, Valeria, Mauri, Ilaria, Incerti, Michele, Sicuri, Giovanni, Miramonti, Valentina, Stefini, Roberto, Spagnoli, Diego, Piparo, Maurizio, Grimod, Gianluca, Regazzoni, Rossana, Vismara, Daniela, Mazzeo, Lucio, Monti, Emanuele, Franzin, Alberto, Vivaldi, Oscar, Maietti, Alessandra, Pini, Elisa, Servello, Domenico, Zekaj, Edvin, DE Michele, Sara, Locatelli, Marco, Borsa, Stefano, Grimoldi, Nadia, Caroli, Manuela, Tariciotti, Leonardo, Abete-Fornara, Giorgia, Vitale, Mario, Leonardi, Matilde, and Broggi, Morgan

Abstract

Background: The aim of this study was to achieve a consensus on the minimum set of outcome measures and predictors to be used in the neurosurgical practice and on the timing of outcome assessment. Methods: A consensus building approach was employed. All neurosurgical departments in Lombardy (Italy) were invited to participate by the Carlo Besta Neurologic Institute IRCCS Foundation. Three workshops were organized during which a multidisciplinary group called Neurosurgical Outcome Network (NEON) was created and the methodology to select outcome measures, predictors, and timing of outcome assessment was established. Eight working groups were created for the different neurosurgical diseases (neuro-oncological, skull base, vascular, traumatic, spinal, peripheral nervous system, malformation, functional) and 8 workshops were organized to identify the outcome measures and predictors specific for each of the neurosurgical diseases based on the experts' clinical practice and the existing literature. Results: A total of 20 neurosurgical departments participated in this study. Specific outcome measures, predictors and the timing of outcome assessment were identified for each of the 8 neurosurgical diseases. Moreover, a list of variables common to all pathologies were identified by the NEON group as further data to be collected. Conclusions: A consensus on the minimum set of outcome measures and predictors and the timing of outcome assessments for 8 neurosurgical diseases was achieved by a group of neurosurgeons of the Lombardy region, called NEON. These sets could be used in future studies for a more homogeneous data collection and as a starting point to reach further agreement also at national and international level.

Published
2023

18. Introduction to Surgical Navigation in Oral Surgery: A Case-Series

Author

Novelli, G, Moretti, M, Meazzini, M, Cassé, C, Mazzoleni, F, Sozzi, D, Novelli, G, Moretti, M, Meazzini, M, Cassé, C, Mazzoleni, F, and Sozzi, D

Abstract

The application of surgical navigation in oral and maxillo-facial surgery has been increasing over time. In fact, computer-assisted surgery provides real-time, precise, and accurate position and guidance during surgery. The purpose of our work is to introduce the evolution of surgical navigation in recent decades, describe some technical aspects of this technology, explore new possibilities of application of surgical navigation in oral surgery, and validate the accuracy of computer-assisted surgery. We included four patients in our sample who underwent virtual planning on the cone beam CT data set and surgical navigation using non-invasive fiducial markers. The first patient presented a dislocated orthodontic arch in the soft tissues of the cheek, while the other patients presented supernumerary and impacted dental elements. Among them, two patients were affected by craniofacial synostosis. We evaluated the accuracy of computer-assisted surgery, calculating the discrepancy between the real and virtual target. In all cases, the target registration error was less than or equal to 1 mm. We can affirm that surgical navigation is a valid tool to enhance oral surgery, guaranteeing an undoubted advantage in terms of the reliability and predictability of the results, especially in complex cases.

Published
2023

23. Circummaxillary Sutures in Patients With Apert, Crouzon, and Pfeiffer Syndromes Compared to Nonsyndromic Children: Growth, Orthodontic, and Surgical Implications

Author

Meazzini, M, Corradi, F, Mazzoleni, F, De Ponti, E, Maccagni, M, Novelli, G, Bozzetti, A, Meazzini M. C., Corradi F., Mazzoleni F., De Ponti E., Maccagni M., Novelli G., Bozzetti A., Meazzini, M, Corradi, F, Mazzoleni, F, De Ponti, E, Maccagni, M, Novelli, G, Bozzetti, A, Meazzini M. C., Corradi F., Mazzoleni F., De Ponti E., Maccagni M., Novelli G., and Bozzetti A.

Abstract

Objective: To evaluate patency of circummaxillary sutures in children with Apert, Crouzon, and Pfeiffer Syndromes and to compare it to a nonsyndromic matched control group. Design: Case–control study. Setting: Tertiary care public hospital. Materials and Methods: Thirty-eight computed tomography (CT) scans of patients affected by syndromic craniofacial synostosis (13 patients with Apert syndrome, 20 patients with Crouzon syndrome, and 5 patients with Pfeiffer syndrome), average age 5 ± 2.8 years, range 1.9 to 12 years, were compared to age- and sex-matched control CTs of 38 nonsyndromic children. Computed tomography scans of the study group had to be performed prior to any midfacial surgery. Main Outcome Measures: Midpalatal suture, zygomaticomaxillary sutures, and pterigomaxillary sutures were evaluated and scored. Results: The syndromic group showed a significant earlier ossification of all sutures compared to the nonsyndromic group. Significant differences were already present in early childhood and continued through adolescence. Conclusions: Based on the differences in terms of maxillary sutural ossification identified, midfacial hypoplasia does not seem to be only secondary to premature cranial base ossification, but also to primary synostosis of facial sutures, thus providing new insights into the pathogenesis of midface deficiency in children with craniofacial-synostosis. Care should be taken when planning any maxillary orthopedics, such as expansion or maxillary protraction, given the high frequency of early fusion of circummaxillary sutures.

Published
2021

24. Long-term incidence of cardiac device complications with intrathoracic versus extrathoracic venous access: results from the PLACE (Planning Lead Access for Cardiac Electrostimulation) study

Author

Ghiglieno, C, primary, Dell’ Era, G, additional, Palmisano, P, additional, Floris, R, additional, Pimpini, L, additional, Coluccia, G, additional, Delogu, G, additional, Colombo, C, additional, Marconetto, C, additional, De Zan, G, additional, D’amico, A, additional, Mazzoleni, F, additional, and Patti, G, additional

Published
2022
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26. The Italian fund for Alzheimer's and other dementias: strategies and objectives to face the dementia challenge

Author

Ancidoni, A., Sciancalepore, F., Bacigalupo, I., Bellomo, G., Canevelli, M., Lacorte, E., Lombardo, F. L., Lorenzini, P., Palazzesi, I., Piscopo, P., Salvi, E., Bianchi, C. B. N. A., Landoni, F., La Sala, L., Di Fiandra, T., Vanacore, N., Basso, C., Bonino, P., Bruni, A. C., Caci, A., Fabbo, A., Giordano, M., Greco, A., Lidonnici, E., Lombardi, A., Lovaldi, F., March, A., Madrigali, S., Palummeri, E., Perratone, P., Scalmana, S., Caffarra, P., Mazzoleni, F., Pirani, A., Trabucchi, M., Belardinelli, M., Possenti, M., Spadin, P., Bargagli, A. M., Bartorelli, L., Biagini, C., Capasso, A., Cozzari, M. P., Gainotti, S., Di Palma, A., Gabelli, C., Gambina, G., Gasparini, M. M., Guaita, A., Izzicupo, F., Notarelli, A., Petrini, C., Riva, L., Secreto, P., Stracciari, A., Losito, G., Ciampa, A., Camilli, F. -M., Carnevale, G., Coclite, D., Crestini, A., Della Gatta, F., Distaso, E., Druda, Y., Esposito, S., Fabrizi, E., Fauci, A., Fumagalli, G., Gasparini, M., Giaquinto, F., Locuratolo, N., Lombardo, F., Martelli, G., Matascioli, F., Mennini, S., Milanese, A., Morelli, S., Napoletano, A., Porrello, M. C., Remoli, G., Rivabene, R., Sagliocca, L., Sciattella, P., Vaccaro, R., Valletta, M., Veronese, N., Vignatelli, L., and Zaccaria, V.

Subjects
Caregivers, Financial Management, Alzheimer Disease, public health, Humans, Dementia, dementia national plan, Public Health, dementia, caregivers, humans, alzheimer disease, financial management
Abstract

The Italian Fund for Alzheimer's and other dementias was approved and signed in December 2021. The Fund is financed with 15 million euros in three years. The main goal is to provide new strategies in the field of dementia with a Public Health perspective. The Fund includes eight main activities that will be monitored and supervised by the Italian National Institute of Health: 1) development of a guideline for the assessment, management and support for people with dementia and their families/carers; 2) updating of the Dementia National Plan (DNP); 3) implementation of the documents of the DNP; 4) conducting surveys dedicated to the Italian Dementia Services; 5) promotion of dementia prevention strategies; 6) training strategies for healthcare professionals, families and caregivers; 7) creation of a National Electronic Record for Dementia; 8) evaluation and monitoring of activities promoted by Regions and Autonomous Provinces in the field of dementia, together with the dementia National Permanent Table. These activities are outlined in detail in the present paper.

Published
2022

27. Prioritizing cleft/craniofacial surgical care after the COVID-19 pandemic

Author

Breugem, C, Smit, H, Mark, H, Davies, G, Schachner, P, Collard, M, Sell, D, Autelitano, L, Rezzonico, A, Mazzoleni, F, Novelli, G, Mossey, P, Persson, M, Mehendale, F, Gaggl, A, Van Gogh, C, Zuurbier, P, Reinart, S, De Graaff, F, Meazzini, C, Breugem C., Smit H., Mark H., Davies G., Schachner P., Collard M., Sell D., Autelitano L., Rezzonico A., Mazzoleni F., Novelli G., Mossey P., Persson M., Mehendale F., Gaggl A., Van Gogh C., Zuurbier P., Reinart S., De Graaff F., Meazzini C., Breugem, C, Smit, H, Mark, H, Davies, G, Schachner, P, Collard, M, Sell, D, Autelitano, L, Rezzonico, A, Mazzoleni, F, Novelli, G, Mossey, P, Persson, M, Mehendale, F, Gaggl, A, Van Gogh, C, Zuurbier, P, Reinart, S, De Graaff, F, Meazzini, C, Breugem C., Smit H., Mark H., Davies G., Schachner P., Collard M., Sell D., Autelitano L., Rezzonico A., Mazzoleni F., Novelli G., Mossey P., Persson M., Mehendale F., Gaggl A., Van Gogh C., Zuurbier P., Reinart S., De Graaff F., and Meazzini C.

Abstract

Background: It is anticipated that in due course the burden of emergency care due to COVID-19 infected patients will reduce sufficiently to permit elective surgical procedures to recommence. Prioritizing cleft/craniofacial surgery in the already overloaded medical system will then become an issue. The European Cleft Palate Craniofacial Association, together with the European Cleft and Craniofacial Initiative for Equality in Care, performed a brief survey to capture a current snapshot during a rapidly evolving pandemic. Methods: A questionnaire was sent to the 2242 participants who attended 1 of 3 recent international cleft/craniofacial meetings. Results: The respondents indicated that children with Robin sequence who were not responding to nonsurgical options should be treated as emergency cases. Over 70% of the respondents indicated that palate repair should be performed before the age of 15 months, an additional 22% stating the same be performed by 18 months. Placement of middle ear tubes, primary cleft lip surgery, alveolar bone grafting, and velopharyngeal insufficiency surgery also need prioritization. Children with craniofacial conditions such as craniosynostosis and increased intracranial pressure need immediate care, whilst children with craniosynostosis and associated obstructive sleep apnea syndrome or proptosis need surgical care within 3 months of the typical timing. Craniosynostosis without signs of increased intracranial pressure needs correction before the age of 18 months. Conclusions: This survey indicates several areas of cleft and craniofacial conditions that need prioritization, but also certain areas where intervention is less urgent. We acknowledge that there will be differences in the post COVID-19 response according to circumstances and policies in individual countries.

Published
2020

37. Platform session

Author

Feigl, G., Rosmarin, W., Weninger, B., Likar, R., Hoogland, P. V., Groen, R. J. M., Vorster, W., Grobbelaar, M., Muller, C. J. F., du Toit, D. F., Moriggl, B., Greher, M., Klauser, A., Eichenberger, U., Prades, J. M., Timoshenko, A., Faye, M., Martin, C. H., Baroncini, M., Baiz, H., Ben Henda, A., Fontaine, C., Baksa, G., Toth, M., Patonay, L., Gonçalves-Ferreira, A., Gonçalves, C., Neto, L., Fonseca, T., Gaspar, H., Rino, J., Fernandes, M., Fernandes, P., Cardoso, H., Miranda, B., Rego, J., Hamel, A., Guillouche, P., Hamel, O., Garçon, M., Lager, S., Blin, Y., Armstrong, O., Robert, R., Rogez, J. M., Le Borgne, J., Kahilogulları, G., Comert, A., Esmer, A. F., Tuccar, E., Tekdemir, I., Ozdemir, M., Odabasi, A. B., Elhan, A., Anand, M. K., Singh, P. R., Verma, M., Raibagkar, C. J., Kim, H. J., Kwak, H. H., Hu, K. S., Francke, J. P., Macchi, V., Porzionato, A., Parenti, A., Metalli, P., Zanon, G. F., De Caro, R., Bernardes, A., Dionísio, J., Messias, P., Patrício, J., Apaydin, N., Uz, A., Evirgen, O., Shim, K. S., Park, H. D., Youn, K. H., Cajozzo, M., Bartolotta, T., Cappello, F., Sunseri, A., Romeo, M., Altieri, G., Modica, G., La Barbera, G., La Marca, G., Valentino, F., Valentino, B., Martino, A., Dees, G., Kleintjes, W. A., Williams, R., Herpe, B., Leborgne, J., Lagier, S., Cordova, A., Pirrello, R., Moschella, F., Mahajan, M. V., Bhat, U. B., Abhayankar, S. V., Ambiye, M. V., Kachlík, D. K., Stingl, J. S., Sosna, B. S., Fára, P. F., Lametschwandtner, A. L., Minnich, B. M., Straka, Z. S., Ifrim, M., Ifrim, C. Feng, Botea, M., Latorre, R., Sun, F., Henry, R., Crisóstomo, V., Cano, F. Gil, Usón, J., Mtez-Gomaríz, F., Climent, S., Hurmusiadis, V., Barrick, S., Barrow, J., Clifford, N., Morgan, F., Wilson, R., Wiseman, L., Fogg, O. A., Loukas, M., Tedman, R. A., Capaccioli, N., Capaccioli, L., Mannini, A., Guazzi, G., Mangoni, M., Paternostro, F., Vagnoli, P. Terrosi, Gulisano, M., Pacini, S., Grignon, B., Jankowski, R., Hennion, D., Zhu, X., Roland, J., Mutiu, G., Tessitore, V., Uzzo, M. L., Bonaventura, G., Milio, G., Spatola, G. F., Ilkan, T., Selcuk, T., Mustafa, A. M., Hamdi, C. H., Emel, T. C., Faruk, U., Hamdi, C. H., Bulent, G., Báča, V., Doubková, A., Kachlík, D., Stingl, J., Saylam, C., Kitiş, Ö., Üçerler, H., Manisahı, E., Gönül, A. S., Dashti, G. H. R., Nematbaksh, M., Mardani, M., Hami, J., Rezaian, M., Radmehr, B., Akbari, M., Paryani, M. R., Gilanpour, H., Zamfir, C., Zamfir, M., Lupusoru, C., Raileanu, C., Lupusoru, R., Bordei, P., Iliescu, D., Şapte, E., Adam, S., Baker, C., Sergi, C., Barberini, F., Ripani, M., Di Nitto, V., Zani, A., Magnosi, F., Heyn, R., Familiari, G., Elgin, U., Demiryurek, D., Berker, N., Ilhan, B., Simsek, T., Batman, A., Bayramoglu, A., Fogg, Q. A., Bartczak, A., Kamionek, M., Kiedrowski, M., Fudalej, M., Wagner, T., Artibani, W., Tiengo, C., Taglialavoro, G., Mazzoleni, F., Scapinelli, R., Ardizzone, E., Cannella, V., Peri, D., Pirrone, R., and Peri, G.

Published
2005
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45. Final report of EURAMET.M.G-K3: regional comparison of absolute gravimeters

Author

Coskun, I., Falk, R., Palinkas, V., Wziontek, H., Rulke, A., Val'Ko, M., Ullrich, C., Butta, H., Kostelecky, J., Bilker-Koivula, M., Naranen, J., Prato, A., Mazzoleni, F., Kirbas, C., Coskun, Van Camp, M., Castelein, S., Bernard, J. D., Lothhammer, A., Schilling, M., Timmen, L., Iacovone, D., Nettis, G., Greco, F., Messina, A. A., Reudink, R., Petrini, M., Dykowski, P., Sekowski, M., Janak, J., Papco, J., Engfeldt, A., and Steffen, H.

Subjects
010309 optics, Gravimeter, Data harmonization, 0103 physical sciences, General Engineering, Constrained least squares, Geodetic datum, 010306 general physics, Geodesy, Mutual recognition, 01 natural sciences, Equivalence (measure theory), Mathematics
Abstract

The regional key comparison of absolute gravimeters, EURAMET.M.G-K3 and the simultaneously organized additional comparison, was held in Germany at the Geodetic Observatory Wettzell of the German Federal Agency for Cartography and Geodesy in the spring of 2018. Here we present the list of the participants who actually performed measurements during the comparison, the data submitted by the operators as well as the results of the determination of the gravity as a function of height at the comparison sites. The measurement strategy is briefly discussed and the results of the data harmonization is documented. Finally, the results of the constrained least squares adjustment are presented including the degrees of equivalence of each gravimeter and the key comparison reference values. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Published
2020

48. Infant ossified cephalohematoma: a review of the surgical management and technical update

Author

Calloni, T, Trezza, A, Mazzoleni, F, Cavaliere, M, Canonico, F, Sganzerla, E, Giussani, C, Calloni, Tommaso, Trezza, Andrea, Mazzoleni, Fabio, Cavaliere, Marilou, Canonico, Francesco, Sganzerla, Erik, Giussani, Carlo, Calloni, T, Trezza, A, Mazzoleni, F, Cavaliere, M, Canonico, F, Sganzerla, E, Giussani, C, Calloni, Tommaso, Trezza, Andrea, Mazzoleni, Fabio, Cavaliere, Marilou, Canonico, Francesco, Sganzerla, Erik, and Giussani, Carlo

Abstract

Cephalohematoma is a subperiosteal collection of blood above the skull. It is associated with operative and prolonged deliveries. In most cases the hematoma spontaneously resolves in a short span of time, usually within one month. In a few cases cephalohematoma can become ossified and require surgical treatment. Traditional belief that ossified cephalohematomas are an exclusively cosmetic issue has been called into question by recent description of EEG anomalies associated to a calcified cephalohematoma. We review relevant surgical literature, and we describe a novel variant of Wong's Radial Cap technique by foregoing healthy bone margin removal, removing the cephalohematoma lamellae in a stepwise fashion and using resorbable plaques for fixation. We furthermore review the rationale, timing and step-by-step execution of the procedure. An exemplary case description is discussed.

Published
2020

50. Negative pressure wound therapy in complex cranio‐maxillofacial and cervical wounds

Author

Novelli, G, DALEFFE, FRANCESCO, BIRRA, GISELLA, Canzi, G, Mazzoleni, F, Boni, P, Maino, C, Giussani, C, Sozzi, D, Bozzetti, A, Novelli, G, Daleffe, F, Birra, G, Canzi, G, Mazzoleni, F, Boni, P, Maino, C, Giussani, C, Sozzi, D, and Bozzetti, A

Subjects
Adult, Male, Wound Healing, Adolescent, Vacuum-assisted closure, Infant, Negative pressure wound therapy, Original Articles, Middle Aged, Plastic Surgery Procedures, Maxillofacial Abnormalities, Young Adult, Treatment Outcome, Child, Preschool, Cervical Vertebrae, Humans, Wounds and Injuries, Surgery, Female, Cranio-maxillofacial wound, Child, VAC Therapy cervical wound, Negative-Pressure Wound Therapy, Aged
Abstract

The care and the management of the healing of difficult wounds at the level of the skull-facial face many problems related to patient compliance and the need to perform multiple dressings, with long periods of healing and, occasionally, a very long hospitalisation period. The introduction and evolution of negative pressure wound therapy (NPWT) in the treatment of difficult wounds has resulted in better healing, with a drastic reduction in terms of time and biological costs to the patient and cost to the health care system. The main aim of this study is to describe and discuss, using out our experience, the usefulness of NPWT in the cranial-facial-cervical region. We studied 16 patients with complex wounds of the cranial-facial-cervical region treated with NPWT. We divided clinical cases in four groups: cervicofacial infectious disease, healing complications in oncological-reconstructive surgery, healing complications of injury with exposure of bone and/or internal fixations and healing complications in traumatic injury with loss of substance. We evaluated complete or incomplete wound healing; application time, related also to hospitalisation time; days of intensive care unit (ICU) stay; management of the upper airways; timing of medication renewal; and patient comfort and compliance (on a scale of 1-5). Depression values were always between -75 and -125 mmHg in a continuous aspiration pattern. For every patient, we used the ActiVAC Therapy Unit, derived from the vacuum-assisted closure system (Kinetic Concepts Inc., San Antonio, TX). Medication renewals were performed every 48-72 hours. The NPWT application time ranged from 4 to 22 days (mean of 11·57 day). Therapy was effective to gain a complete restitutio ad integrum in every patient included in the group of cervicofacial infectious disease. Therapy has, however, been well tolerated in our series; this is probably due to the decreased number of applications, the ease of use and the comfort of the system relative to traditional dressing. Results were satisfactory for most of cases treated; faster and more effective wound healing was achieved. The lower number of NPWT applications, relating to standard dressings, led to an increase in patient comfort and compliance and a decrease in the use of medical, and in some cases economic, resources according to international literature.

Published
2017

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