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29 results on '"Mazzoni, Carlotta"'

1. Differential Diagnoses in Clinical Mimics

Author

Del Franco, Annamaria, Merlo, Marco, Biagioni, Giulia, Mazzoni, Carlotta, Pagura, Linda, Allegro, Valentina, Cappelli, Francesco, Pieroni, Maurizio, Olivotto, Iacopo, Emdin, Michele, editor, Vergaro, Giuseppe, editor, Aimo, Alberto, editor, and Fontana, Marianna, editor

Published
2024
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2. Impact of the Noninvasive Diagnostic Algorithm on Clinical Presentation and Prognosis in Cardiac Amyloidosis

Author

Tini, Giacomo, Cristiano, Ernesto, Zampieri, Mattia, Ponziani, Alberto, Porcari, Aldostefano, Zanoletti, Margherita, Mazzoni, Carlotta, Sclafani, Matteo, Saturi, Giulia, Lalario, Andrea, Labate, Marianna Eleonora, Autore, Camillo, Barbato, Emanuele, Perfetto, Federico, Biagini, Elena, Sinagra, Gianfranco, Canepa, Marco, Merlo, Marco, Longhi, Simone, Cappelli, Francesco, and Musumeci, Beatrice

Published
2024
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4. Atrial electrofunctional predictors of incident atrial fibrillation in cardiac amyloidosis

Author

Sinigiani, Giulio, De Michieli, Laura, Porcari, Aldostefano, Zocchi, Chiara, Sorella, Anna, Mazzoni, Carlotta, Bisaccia, Giandomenico, De Luca, Antonio, Di Bella, Gianluca, Gregori, Dario, Perfetto, Federico, Merlo, Marco, Sinagra, Gianfranco, Iliceto, Sabino, Perazzolo Marra, Martina, Corrado, Domenico, Ricci, Fabrizio, Cappelli, Francesco, and Cipriani, Alberto

Published
2024
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8. Atrial electro-functional predictors of incident atrial fibrillation in cardiac amyloidosis

Author

Sinigiani, Giulio, primary, De Michieli, Laura, additional, Porcari, Aldostefano, additional, Zocchi, Chiara, additional, Sorella, Anna, additional, Mazzoni, Carlotta, additional, Bisaccia, Giandomenico, additional, De Luca, Antonio, additional, Di Bella, Gianluca, additional, Gregori, Dario, additional, Perfetto, Federico, additional, Merlo, Marco, additional, Sinagra, Gianfranco, additional, Iliceto, Sabino, additional, Perazzolo Marra, Martina, additional, Corrado, Domenico, additional, Ricci, Fabrizio, additional, Cappelli, Francesco, additional, and Cipriani, Alberto, additional

Published
2024
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10. Serial changes in CPET parameters in untreated patients with transthyretin cardiac amyloidosis

Author

Argirò, Alessia, primary, Silverii, Maria Vittoria, additional, Burgisser, Costanza, additional, Fattirolli, Francesco, additional, Baldasseroni, Samuele, additional, Di Mario, Carlo, additional, Zampieri, Mattia, additional, Biagioni, Giulia, additional, Mazzoni, Carlotta, additional, Chiti, Chiara, additional, Allinovi, Marco, additional, Ungar, Andrea, additional, Perfetto, Federico, additional, and Cappelli, Francesco, additional

Published
2023
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14. Prevalence of transthyretin-related amyloidosis in Tuscany: Data from the regional population-based registry

Author

Cappelli, Francesco, primary, Del Franco, Annamaria, additional, Vergaro, Giuseppe, additional, Mazzoni, Carlotta, additional, Argirò, Alessia, additional, Pieroni, Maurizio, additional, Giacomin, Elisa, additional, Poli, Serena, additional, Allinovi, Marco, additional, Olivotto, Iacopo, additional, Pieroni, Federica, additional, Scaletti, Cristina, additional, Emdin, Michele, additional, and Perfetto, Federico, additional

Published
2023
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16. Stage-specific therapy for hypertrophic cardiomyopathy

Author

Argirò, Alessia, primary, Zampieri, Mattia, additional, Marchi, Alberto, additional, Cappelli, Francesco, additional, Del Franco, Annamaria, additional, Mazzoni, Carlotta, additional, Cecchi, Franco, additional, and Olivotto, Iacopo, additional

Published
2023
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17. Diagnostic pathways to wild‐type transthyretin amyloid cardiomyopathy: a multicentre network study

Author

Tini, Giacomo, primary, Milani, Paolo, additional, Zampieri, Mattia, additional, Caponetti, Angelo G., additional, Fabris, Francesca, additional, Foli, Andrea, additional, Argirò, Alessia, additional, Mazzoni, Carlotta, additional, Gagliardi, Christian, additional, Longhi, Simone, additional, Saturi, Giulia, additional, Vergaro, Giuseppe, additional, Aimo, Alberto, additional, Russo, Domitilla, additional, Varrà, Guerino G., additional, Serenelli, Matteo, additional, Fabbri, Gioele, additional, De Michieli, Laura, additional, Palmiero, Giuseppe, additional, Ciliberti, Giuseppe, additional, Carigi, Samuela, additional, Sessarego, Eugenio, additional, Mandoli, Giulia E., additional, Ricci Lucchi, Giulia, additional, Rella, Valeria, additional, Monti, Enrico, additional, Gardini, Elisa, additional, Bartolotti, Michela, additional, Crotti, Lia, additional, Merli, Elisa, additional, Mussinelli, Roberta, additional, Vianello, Pier Filippo, additional, Cameli, Matteo, additional, Marzo, Francesca, additional, Guerra, Federico, additional, Limongelli, Giuseppe, additional, Cipriani, Alberto, additional, Perlini, Stefano, additional, Obici, Laura, additional, Perfetto, Federico, additional, Autore, Camillo, additional, Porto, Italo, additional, Rapezzi, Claudio, additional, Sinagra, Gianfranco, additional, Merlo, Marco, additional, Musumeci, Beatrice, additional, Emdin, Michele, additional, Biagini, Elena, additional, Cappelli, Francesco, additional, Palladini, Giovanni, additional, and Canepa, Marco, additional

Published
2023
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18. Prevalence of anxiety and depression symptoms in a sample of outpatients with ATTR cardiac amyloidosis

Author

Smorti, Martina, primary, Ponti, Lucia, additional, Soffio, Francesco, additional, Argirò, Alessia, additional, Perfetto, Federico, additional, Zampieri, Mattia, additional, Mazzoni, Carlotta, additional, Tomberli, Alessia, additional, Allinovi, Marco, additional, Di Mario, Carlo, additional, Olivotto, Iacopo, additional, and Cappelli, Francesco, additional

Published
2023
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19. 965 PROGNOSTIC VALUE OF CARDIOPULMONARY EXERCISE TESTING IN PATIENTS WITH TRANSTHYRETIN CARDIAC AMYLOIDOSIS

Author

Silverii, Maria Vittoria, primary, Argiro, Alessia, additional, Baldasseroni, Samuele, additional, Zampieri, Mattia, additional, Fumagalli, Carlo, additional, Mazzoni, Carlotta, additional, Di Mario, Carlo, additional, Perfetto, Federico, additional, Fattirolli, Francesco, additional, Olivotto, Iacopo, additional, and Cappelli, Francesco, additional

Published
2022
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20. Prognostic value of cardiopulmonary exercise testing in patients with transthyretin cardiac amyloidosis

Author

Silverii, Maria Vittoria, primary, Argirò, Alessia, additional, Baldasseroni, Samuele, additional, Fumagalli, Carlo, additional, Zampieri, Mattia, additional, Guerrieri, Ludovica, additional, Bartolini, Simone, additional, Mazzoni, Carlotta, additional, Burgisser, Costanza, additional, Tomberli, Alessia, additional, Di Mario, Carlo, additional, Marchionni, Niccolò, additional, Olivotto, Iacopo, additional, Perfetto, Federico, additional, Fattirolli, Francesco, additional, and Cappelli, Francesco, additional

Published
2022
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27. Early diagnosis, disease stage and prognosis in wild-type transthyretin amyloid cardiomyopathy: The DIAMOND study.

Author

Tini G, Musumeci B, Milani P, Zampieri M, Caponetti AG, Fabris F, Foli A, Argirò A, Mazzoni C, Gagliardi C, Longhi S, Saturi G, Vergaro G, Aimo A, De Fazio L, Varrà GG, Serenelli M, Fabbri G, De Michieli L, Palmiero G, Ciliberti G, Carigi S, Zanoletti M, Mandoli GE, Lucchi GR, Rella V, Monti E, Gardini E, Bartolotti M, Crotti L, Merli E, Mussinelli R, Vianello PF, Cameli M, Marzo F, Guerra F, Limongelli G, Cipriani A, Perlini S, Obici L, Perfetto F, Barbato E, Porto I, Sinagra G, Merlo M, Emdin M, Biagini E, Cappelli F, Palladini G, and Canepa M

Abstract

Aims: Disease staging and prognostic scoring in wild-type transthyretin-related cardiac amyloidosis (ATTRwt-CA) can be captured by two systems (NAC and Columbia scores). However, uncertainty remains as epidemiology of the disease is evolving rapidly. We evaluated features associated with staging systems across ATTRwt-CA patients from different diagnostic pathways, and their association with prognosis., Methods: We performed an analysis on DIAMOND patients with available data to evaluate NAC and Columbia score. DIAMOND was a retrospective study from 17 Italian referral centres for CA, enrolling 1281 patients diagnosed between 2016 and 2021, and aimed at describing characteristics of pathways leading to ATTRwt-CA diagnosis. Of the original cohort, 811 patients were included in this analysis. Each patient had NAC and Columbia score calculated. Patients were grouped according to NAC and Columbia scoring classes. We described characteristics of patients according to staging classes and diagnostic pathways at diagnosis. Prevalence of early diagnoses, defined as NAC Ia, NYHA class I, no use of diuretics, no history of heart failure (HF) hospitalizations nor of atrial fibrillation prior to diagnosis, was investigated. Finally, prognostic variables were tested alone and grouped as NAC or Columbia scores in Cox univariate and multivariate regression analyses. Prognosis was investigated as all-cause mortality, in the whole population and dividing patients in HF versus other diagnostic pathways., Results: Only 1% of the study population had an early ATTRwt-CA diagnosis. Distribution of prognostic variables and of NAC and Columbia classes was heterogeneous across diagnostic pathways. The prevalence of NAC III and Columbia III was higher in the HF diagnostic pathway, but all NAC and Columbia classes were present in all pathways. Both NAC and Columbia scores were associated with all-cause mortality at univariate Cox regression analysis in the whole population, in patients from the HF diagnostic pathway and in those from other pathways. At multivariate analysis, Columbia score remained significantly associated with the outcome, together with age at diagnosis, left ventricular ejection fraction and maximal wall thickness., Conclusions: In this contemporary nationwide cohort, an ATTRwt-CA early diagnosis was very rare. Disease staging with NAC and Columbia scoring systems determined classes of patients with heterogeneous features. Both scores were significantly associated with mortality, but other variables also had prognostic significance., (© 2024 The Author(s). ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.)

Published
2024
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28. [Therapeutic approaches in hypertrophic cardiomyopathy: from symptom relief to precision therapy].

Author

Argirò A, Zampieri M, Marchi A, Del Franco A, Pàlinkàs ED, Biagioni G, Chiti C, Mazzoni C, Fornaro A, Targetti M, Cappelli F, and Olivotto I

Subjects
Humans, Quality of Life, Cardiomyopathy, Hypertrophic drug therapy, Heart Failure, Ventricular Outflow Obstruction, Left
Abstract

Hypertrophic cardiomyopathy is the most common genetic cardiomyopathy. Main complications include the development of arrhythmias and heart failure, and the latter may be triggered by left ventricular outflow tract obstruction. The treatment of left ventricular outflow tract obstruction includes pharmacological therapies (beta-blockers, calcium channel blockers, disopyramide) and septal reduction therapies (alcohol septal ablation, surgical myectomy). Myosin inhibitors represent a new therapeutic opportunity and in recent clinical trials proved effective in symptom relief, improvement of functional capacity and quality of life in patients with obstructive hypertrophic cardiomyopathy. In this narrative review we will summarize the available and under development therapeutic approaches for hypertrophic cardiomyopathy.

Published
2023
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29. ST-segment elevation myocardial infarction due to septic coronary embolism: a case report.

Author

Mazzoni C, Scheggi V, Marchionni N, and Stefano P

Abstract

Background: Coronary artery embolism is an infrequent cause of type 2 myocardial infarction which can be due to arterial thromboembolism or septic embolism. While systemic embolization is one of the most acknowledged and threatened complications of infective endocarditis, coronary localization of the emboli causing acute myocardial infarction is exceedingly rare occurring in <1% of cases., Case Summary: A 52-year-old man with a history of Bentall procedure and redo aortic valve replacement due to prosthetic degeneration (11 years prior to the current presentation) presented to the emergency department with high-grade fever and myalgias. Shortly after his arrival, he experienced typical chest pain and an electrocardiogram demonstrated signs of inferior ST-elevation myocardial infarction: coronary angiography showed a lesion of presumed embolic origin at the level of the mid-distal circumflex coronary artery which was treated with embolectomy. Transthoracic and transoesophageal echocardiography highlighted the presence of a periaortic abscess. The final diagnosis of infective endocarditis as the cause of septic coronary artery embolization was confirmed with a Positron Emission Tomography-Computed Tomography (PET-CT) exam and by the growth of Staphylococcus lugdunensis on repeated blood cultures. The patient underwent successful redo Bentall surgery the good outcome was confirmed at 1-month follow-up., Discussion: Type 2 myocardial infarction caused by coronary embolism is a rare presentation of infective endocarditis and requires a high level of suspicion for its diagnosis. Prosthetic heart valves are a predisposing factor for infective endocarditis: aortic root abscess requires surgery as it rarely regresses with antibiotic therapy., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.)

Published
2021
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