290 results on '"McKee, Krisha"'
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2. Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
3. Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains
4. Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases
5. Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design
6. Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life
7. Ultrapotent Broadly Neutralizing Human‐llama Bispecific Antibodies against HIV‐1.
8. Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody
9. Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.
10. Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain
11. Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
12. Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen
13. Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization
14. Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry
15. Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
16. Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency
17. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
18. Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies
19. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma
20. De novo identification of VRC01 class HIV-1–neutralizing antibodies by next-generation sequencing of B-cell transcripts
21. Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life
22. Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization
23. Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains
24. Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys
25. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
26. Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
27. An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
28. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor
29. Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography
30. Eliminating antibody polyreactivity through addition of N-linked glycosylation
31. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
32. A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention
33. Potent Anti-Viral Activity of a Trispecific HIV Antibody in SHIV-Infected Monkeys
34. Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
35. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
36. Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition
37. A Structure-Based Matrix Approach Yields Improved VRC01-Class Antibodies for HIV-1 Therapy and Prevention
38. Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies
39. Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability
40. Passive infusion of Fc-modified neutralizing antibodies does not affect the dynamics of plasma virus decay in SHIV-infected macaques
41. Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual
42. Structure of Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition
43. Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
44. Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs
45. Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer
46. Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates
47. Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
48. Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors
49. A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope
50. Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity
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