Author: "Meaudre, Céline" - Searchworks@Jio Institute Digital Library Search Results

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Author: Iglesias, Maria Candela, Briceno, Olivia, Gostick, Emma, Moris, Arnaud, Meaudre, Céline, Price, David A., Ungeheuer, Marie-Noëlle, Saez-Cirion, Asier, Mallone, Roberto, and Appay, Victor
Published: 2013
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Author: Antoni, Guillemette, Guergnon, Julien, Meaudre, Céline, Samri, Assia, Boufassa, Faroudy, Goujard, Cécile, Lambotte, Olivier, Autran, Brigitte, Rouzioux, Christine, Costagliola, Dominique, Meyer, Laurence, and Theodorou, Ioannis
Published: 2013
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Author: Iglesias, Maria Candela, Briceno, Olivia, Gostick, Emma, Moris, Arnaud, Meaudre, Céline, Price, David A., Ungeheuer, Marie-Noëlle, Saez-Cirion, Asier, Mallone, Roberto, and Appay, Victor
Subjects: *HLA histocompatibility antigens, *HIV, *CD8 antigen, *T cells, *EPITOPES, *IMMUNE response
Abstract: Abstract: The factors that determine the immunodominance, efficacy and almost ubiquitous presence of CD8+ T-cell responses to the HLA-B27-restricted HIV-1 p24 Gag-derived KK10 epitope remain to be fully elucidated. Here, we show that neither the precursor frequency nor the priming capacity of KK10-reactive CD8+ T-cells within the naïve pool differ substantially in comparison to other specificities. These data implicate alternative mechanisms in the relative protection conferred by CD8+ T-cell responses to this epitope. [Copyright &y& Elsevier]
Published: 2013
Full Text: View/download PDF

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