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8 results on '"Medina-Bastidas, Diana"'

4. Gestational Weight Gain Influences the Adipokine-Oxidative Stress Association during Pregnancy

Author

Solis Paredes, Juan Mario, primary, Perichart Perera, Otilia, additional, Montoya Estrada, Araceli, additional, Reyes Muñoz, Enrique, additional, Espino y Sosa, Salvador, additional, Ortega Castillo, Veronica, additional, Medina Bastidas, Diana, additional, Tolentino Dolores, Maricruz, additional, Sanchez Martinez, Maribel, additional, Nava Salazar, Sonia, additional, and Estrada Gutierrez, Guadalupe, additional

Published
2021
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5. Placental Microarray Profiling Reveals Common mRNA and lncRNA Expression Patterns in Preeclampsia and Intrauterine Growth Restriction

Author

Medina-Bastidas, Diana, primary, Guzmán-Huerta, Mario, additional, Borboa-Olivares, Hector, additional, Ruiz-Cruz, César, additional, Parra-Hernández, Sandra, additional, Flores-Pliego, Arturo, additional, Salido-Guadarrama, Ivan, additional, Camargo-Marín, Lisbeth, additional, Arambula-Meraz, Eliakym, additional, and Estrada-Gutierrez, Guadalupe, additional

Published
2020
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6. Macrophage Populations in Visceral Adipose Tissue from Pregnant Women: Potential Role of Obesity in Maternal Inflammation

Author

Bravo-Flores, Eyerahi, primary, Mancilla-Herrera, Ismael, additional, Espino y Sosa, Salvador, additional, Ortiz-Ramirez, Marco, additional, Flores-Rueda, Verónica, additional, Ibargüengoitia-Ochoa, Francisco, additional, Ibañez, Carlos, additional, Zambrano, Elena, additional, Solis-Paredes, Mario, additional, Perichart-Perera, Otilia, additional, Sanchez-Martinez, Maribel, additional, Medina-Bastidas, Diana, additional, Reyes-Muñoz, Enrique, additional, and Estrada-Gutierrez, Guadalupe, additional

Published
2018
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8. New Insights into the Role of Matrix Metalloproteinases in Preeclampsia.

Author

Sosa, Salvador Espino Y., Flores-Pliego, Arturo, Espejel-Nuñez, Aurora, Medina-Bastidas, Diana, Vadillo-Ortega, Felipe, Zaga-Clavellina, Veronica, and Estrada-Gutierrez, Guadalupe

Subjects
MATRIX metalloproteinases, PREECLAMPSIA, TROPHOBLAST, PREGNANCY complications, PATHOLOGICAL physiology, HYPERTENSION
Abstract

Preeclampsia is a severe pregnancy complication globally, characterized by poor placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs) exhibit proteolytic activity implicated in the efficiency of trophoblast invasion to the uterine wall, and a dysregulation of these enzymes has been linked to preeclampsia. A decrease in MMP-2 and MMP-9 interferes with the normal remodeling of spiral arteries at early pregnancy stages, leading to the initial pathophysiological changes observed in preeclampsia. Later in pregnancy, an elevation in MMP-2 and MMP-9 induces abnormal release of vasoactive factors conditioning hypertension. Although these two enzymes lead the scene, other MMPs like MMP-1 and MMP-14 seem to have a role in this pathology. This review gathers published recent evidence about the implications of different MMPs in preeclampsia, and the potential use of these enzymes as emergent biomarkers and biological therapeutic targets, focusing on studies involving human subjects. [ABSTRACT FROM AUTHOR]

Published
2017
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