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43 results on '"Medina-Pestana, Jose Osmar"'

2. Nephrology in Brazil

Author

Moura-Neto, José A., Silva, Cassiano Augusto Braga, Ponce, Daniela, Mastroianni Kirsztajn, Gianna, Medina Pestana, José Osmar, Foresto, Renato Demarchi, Moura, Ana Flavia, Martins, Carmen Tzanno Branco, Souza, Edison, do Nascimento, Marcelo Mazza, Suassuna, José Hermógenes Rocco, Moura-Neto, José A., editor, Divino-Filho, José Carolino, editor, and Ronco, Claudio, editor

Published
2021
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3. Observational Study Evaluating the Outcome of Cirrhotic Hepatitis C Patients Submitted to Renal Transplantation

Author

Emori, Christini Takemi, Uehara, Sílvia Naomi Oliveira, Amaral, Ana Cristina, Carvalho-Filho, Roberto José, Moreira, Sílvia Regina, Sandra de Souza e Silva, Ivonete, Lanzoni, Valéria Pereira, Silva-Souza, Ana Lucia, Gama, Raimundo Araújo, Soares Nunes, Eunice Jadriana, Serra Leopércio, Ana Paula, Appel, Flávia, Regina de Almeida Carvalho, Sandra, Benedito Silva, Antônio Eduardo, Medina-Pestana, José Osmar, and Gomes Ferraz, Maria Lucia

Published
2020
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4. Distinct Outcomes of Kidney Transplant Recipients With Recent COVID-19 According to the Timing of Infection

Author

Manfro, Arthur Gus, de Sandes-Freitas, Tainá Veras, Garcia, Valter Duro, Keitel, Elizete, Cristelli, Marina Pontello, Viana, Laila Almeida, Ferreira, Gustavo Fernandes, Campos, Juliana Bastos, Simão, Denise Rodrigues, Coelho, Maria Eduarda Heinzen de Almeida, Costa, Kellen Micheline Alves Henrique, Pereira Júnior, Tomás, Moschetta, Marina Oliboni, Baptista, Maria Alice Sperto Ferreira, Simões, Marcela Giraldes, Kroth, Leonardo Viliano, Deboni, Luciane Monica, Esmeraldo, Ronaldo de Matos, Medina-Pestana, Jose Osmar, Manfro, Roberto Ceratti, Fernandes Charpiot, Ida Maria Maximina, Aparecida Zanocco, Juliana, Sartori Giaretta, Débora, Alexandre Vieira, Marcos, de Mattos Brito Oliveira Sales, Maria Luiza, Alves Ferreira, Teresa Cristina, Cronenberge Sousa, Katia, Azevedo Matuck, Tereza, De Boni Monteiro de Carvalho, Deise, da Silveira Rioja, Suzimar, Hermógenes Rocco Suassuna, José, Lage Madeira, Rafael, Simone Vilaça, Sandra, de Lourdes Noronha, Irene, da Rocha Martinez, Tania Leme, Modelli de Andrade, Luís Gustavo, and de Barros Almeida, Ricardo Augusto Monteiro

Published
2022
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6. Renal function at 12 months of kidney transplantation comparing tacrolimus and mycophenolate with tacrolimus and mTORi in donors with different KDPI ranges. A multicenter cohort study using propensity scoring

Author

Rodrigues, Arlisson Macedo, primary, Tanno, Mariana Tavares, additional, Contti, Mariana Moraes, additional, Nga, Hong Si, additional, Valiatti, Mariana Farina, additional, Costa, Silvana Daher, additional, Sandes-Freitas, Tainá Veras de, additional, Esmeraldo, Ronaldo de Matos, additional, Assunção, Camila Marinho, additional, Tassi, Juliana Bastos Campos, additional, Ferreira, Gustavo Fernandes, additional, Felipe, Claudia Rosso, additional, Medina Pestana, Jose Osmar, additional, Silva, Helio Tedesco, additional, and Andrade, Luis Gustavo Modelli de, additional

Published
2023
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7. Hepatitis B Reactivation in HBsAg Negative Renal Transplant Patients with Evidence of Previous HBV Infection: A Not Neglectable Occurrence

Author

Leopercio, Ana Paula, primary, Emori, Christini, additional, Neiva, Elisabete Calore, additional, Silva Souza, Ana Lucia, additional, Amaral, Ana Cristina, additional, Vieira, Gustavo Almeida, additional, Gama, Raimundo Araujo, additional, Medina-Pestana, Jose Osmar, additional, and Ferraz, Maria Lúcia, additional

Published
2022
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11. Temporal Reduction in COVID-19-Associated Fatality Among Kidney Transplant Recipients: The Brazilian COVID-19 Registry Cohort Study

Author

Sandes-Freitas, Tainá Veras de, Cristelli, Marina Pontello, Requião-Moura, Lucio Roberto, Modelli de Andrade, Luís Gustavo [UNESP], Viana, Laila Almeida, Garcia, Valter Duro, de Oliveira, Claudia Maria Costa, Esmeraldo, Ronaldo de Matos, de Lima, Paula Roberta, Charpiot, Ida Maria Maximina Fernandes, Ferreira, Teresa Cristina Alves, Franco, Rodrigo Fontanive, Costa, Kellen Micheline Alves Henrique, Simão, Denise Rodrigues, Ferreira, Gustavo Fernandes, Santana, Viviane Brandão Bandeira de Mello, Almeida, Ricardo Augusto Monteiro de Barros [UNESP], Deboni, Luciane Monica, Saldanha, Anita Leme da Rocha, Noronha, Irene de Lourdes, Oliveira, Lívia Cláudio de, Carvalho, Deise De Boni Monteiro de, Oriá, Reinaldo Barreto, Medina-Pestana, Jose Osmar, Tedesco-Silva Junior, Helio, Universidade Federal do Ceará, Hospital Universitário Walter Cantídio, Hospital Geral de Fortaleza, Hospital do Rim, Universidade Federal de São Paulo (UNIFESP), Hospital Israelita Albert Einstein, Universidade Estadual Paulista (UNESP), Santa Casa de Misericórdia de Porto Alegre, Faculdade de Medicina de São José do Rio Preto (FAMERP), Universidade Federal do Maranhão, Universidade Federal do Rio Grande do Sul, Hospital Universitário Onofre Lopes (HOUL), Hospital Santa Isabel, Santa Casa de Misericórdia de Juiz de Fora, Hospital de Base do Distrito Federal, Hospital Municipal São José (HMSJ), Hospital Beneficência Portuguesa de São Paulo (BP), Universidade de São Paulo (USP), Universidade de Brasília (UnB), and Hospital São Francisco na Providência de Deus

Subjects
kidney transplant, Cohort Studies, Transplantation, Sars-CoV-2, SARS-CoV-2, coronavirus, COVID-19, Humans, Registries, renal transplantation, Covid-19, Kidney Transplantation, Transplant Recipients
Abstract

Made available in DSpace on 2022-04-29T08:46:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Novartis Pharma Data from the general population suggest that fatality rates declined during the course of the pandemic. This analysis, using data extracted from the Brazilian Kidney Transplant COVID-19 Registry, seeks to determine fatality rates over time since the index case on March 3rd, 2020. Data from hospitalized patients with RT-PCR positive SARS-CoV-2 infection from March to August 2020 (35 sites, 878 patients) were compared using trend tests according to quartiles (Q1: 140 days after the index case). The 28-day fatality decreased from 29.5% (Q1) to 18.8% (Q4) (pfor-trend = 0.004). In multivariable analysis, patients diagnosed in Q4 showed a 35% reduced risk of death. The trend of reducing fatality was associated with a lower number of comorbidities (20.7–10.6%, pfor-trend = 0.002), younger age (55–53 years, pfor-trend = 0.062), and better baseline renal function (43.6–47.7 ml/min/1.73 m2, pfor-trend = 0.060), and were confirmed by multivariable analysis. The proportion of patients presenting dyspnea (pfor-trend = 0.001) and hypoxemia (pfor-trend < 0.001) at diagnosis, and requiring intensive care was also found reduced (pfor-trend = 0.038). Despite possible confounding variables and time-dependent sampling differences, we conclude that COVID-19-associated fatality decreased over time. Differences in demographics, clinical presentation, and treatment options might be involved. Programa de Pós-Graduação em Ciências Médicas Departamento de Medicina Clínica Faculdade de Medicina Universidade Federal do Ceará Hospital Universitário Walter Cantídio Hospital Geral de Fortaleza Hospital do Rim Departamento de Medicina Divisão de Nefrologia Universidade Federal de São Paulo Unidade de Transplante Renal Hospital Israelita Albert Einstein Departamento de Medicina Interna Universidade Estadual Paulista-UNESP Santa Casa de Misericórdia de Porto Alegre Hospital de Base Faculdade de Medicina de São José do Rio Preto (FAMERP) Universidade Federal do Maranhão Hospital de Clínicas de Porto Alegre Universidade Federal do Rio Grande do Sul Divisão de Nefrologia e Transplante Renal Hospital Universitário Onofre Lopes (HOUL) Hospital Santa Isabel Santa Casa de Misericórdia de Juiz de Fora Hospital de Base do Distrito Federal Hospital Municipal São José (HMSJ) Hospital Beneficência Portuguesa de São Paulo (BP) Divisão de Nefrologia Hospital das Clínicas Faculdade de Medicina Universidade de São Paulo Unidade de Transplantes Hospital Universitário de Brasília Universidade de Brasília (UnB) Hospital São Francisco na Providência de Deus Departamento de Medicina Interna Universidade Estadual Paulista-UNESP

Published
2022
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17. Use of mTOR inhibitor as prophylaxis for cytomegalovirus disease after kidney transplantation: A natural experiment

Author

Cristelli, Marina Pontelo, primary, Felipe, Claudia Rosso, additional, Prizmic, Paulo Sergio de Souza, additional, Azevedo, Vega Figueiredo Dourado, additional, Viana, Laila Almeida, additional, Tavares, Melissa Gaspar, additional, Wagner de Castro Lima Santos, Daniel, additional, Paula, Mayara Ivani, additional, Medina‐Pestana, Jose Osmar, additional, and Tedesco‐Silva Junior, Helio, additional

Published
2019
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21. PERFIL DOS TRANSPLANTADOS RENAIS COM INFECÇÃO OU DOENÇA POR CITOMEGALOVÍRUS TRATADOS COM FOSCARNET E ANÁLISE DOS DESFECHOS APÓS A CONVERSÃO DE IMUNOSSUPRESSÃO PARA INIBIDOR DE MTOR

Author

Foresto, Renato Demarchi, primary, Santos, Daniel Wagner Castro Lima, additional, Leytón, Alejandro Tulio Zapata, additional, Hazin, Maria Amélia Aguiar, additional, Viana, Laila Almeida, additional, Silva‐Junior, Helio Tedesco, additional, and Medina‐Pestana, Jose Osmar, additional

Published
2018
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25. The effect of anti-thymocyte globulin and everolimus on the kinetics of cytomegalovirus viral load in seropositive kidney transplant recipients without prophylaxis

Author

Basso, Geovana, primary, Felipe, Claudia Rosso, additional, Cristelli, Marina Pontello, additional, Mansur Siliano, Juliana, additional, Viana, Laila, additional, Ferreira Brigido, Alexandra Nicolau, additional, Stopa Martins, Suelen Bianca, additional, de Castro Lima Santos, Daniel Wagner, additional, Aguiar, Wilson Ferreira, additional, Tedesco-Silva Junior, Helio, additional, and Medina-Pestana, Jose Osmar, additional

Published
2018
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26. Kidney Allograft Cyst Infection

Author

Ramos de Freitas, Geraldo Rubens, Benjamens, Stan, Gonçalves, Priscila Dias, Cascelli de Azevedo, Maria Leticia, Reis da Silva Filho, Evandro, Medina-Pestana, José Osmar, Pol, Robert A., and Reis, Thiago

Published
2020
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37. Renal transplantation with and without bladder augmentation in children posterior urethral valve is there a difference in the long term?

Author

Pires, Jesus, primary, Rosito, Tiago, additional, Pereira, Daniel, additional, Hasegawa, Endric, additional, Liguori, Riberto, additional, Garrone, Gilmar, additional, Ottoni, Sergio, additional, Almeida, Claudio, additional, Medina Pestana, Jose Osmar, additional, Ortiz, Valdemar, additional, and Macedo Junior, Antonio, additional

Published
2008
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42. A randomized clinical trial comparing Nitrofurazone‐coated and uncoated urinary catheters in kidney transplant recipients: Results from a pilot study.

Author

Menezes, Fernando Gatti, Corrêa, Luci, Camargo, Luis Fernando Aranha, Medina‐Pestana, Jose Osmar, and Aguiar, Wilson Ferreira

Subjects
URINARY catheters, BACTERIURIA, CATHETER-associated urinary tract infections, KIDNEY transplantation, CLINICAL trials, URINARY tract infections, PILOT projects
Abstract

Background: Urinary tract infections are frequent complications early after kidney transplantation, and the use of antimicrobial coated catheters in settings other than transplantation has shown promising results for infection prevention. The purpose of this study was to compare the efficacy of Nitrofurazone‐coated silicone urinary catheters with non‐impregnated silicone urinary catheters in reducing bacteriuria and urinary tract infections in kidney transplant recipients. Methods: This single‐center study, randomized controlled trial at the Hospital do Rim, a tertiary referral center in kidney transplantation, located in São Paulo, Brazil. Subjects involved living donor kidney transplant recipients, and were randomized 1:1 ratio with a computer‐generated system to a Nitrofurazone‐coated silicone urinary catheter and non‐impregnated silicone urinary catheter from March 2013 to December 2014. Patients with asymptomatic bacteriuria or urinary tract infection at baseline, deceased kidney transplant donors, patients with known hypersensitivity to nitrofurantoin, pregnancy, and those refusing to sign the informed consent form were excluded from the study. Results: Two hundred fourteen subjects were randomized and one hundred seventy‐six completed the study. There were no differences in the rates of asymptomatic bacteriuria (12.5% in the Nitrofurazone group and 11.4% in the control group, P = 0.99) and urinary tract infection (8% and 6.8%, P = 0.99) and the incidence of side effects was more frequent in the Nitrofurazone‐impregnated silicone urinary catheter group (46.6% and 26.1%, P = 0.007). Conclusion: The study suggests that there is no beneficial effect of the employment of Nitrofurazone‐coated urinary catheter. Trial registration number: ISRCTN57888785. [ABSTRACT FROM AUTHOR]

Published
2019
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43. Complement activation in chronic kidney disease and dialysis

Author

Gaya da Costa, Mariana, Son ,van, Willem, Medina Pestana, Jose Osmar, Seelen, Marcus, and Poppelaars, Felix

Abstract

Chronic kidney disease (CKD) is a growing health problem with a prevalence of approximately 10-15% worldwide. Progression of CKD leading to end-stage renal disease requires renal replacement therapy. In the Netherlands, approximately 6500 patients receive dialysis. Although dialysis is a life-saving treatment, the life expectancy and the quality of life of these patients is inferior to the general population. The complement system, the major part of the innate immune system, has been proposed to play a vital role in the inflammatory response induced by dialysis and could be the missing link between high morbidity and mortality and dialysis. In this thesis, we investigated the role of the complement system in different contexts: in healthy, CKD patients and during dialysis. We found that both types of dialysis, hemodialysis and peritoneal dialysis lead to complement activation. In hemodialysis patients, complement activation during the initial minutes of the hemodialysis session was related to the development of future cardiovascular event. Furthermore, in peritoneal dialysis complement activation occurred not only locally, in the peritoneal cavity, but also systemically. We also explored the complement activating ability of intravenous iron formulations, since CKD patients, dialysis dependents or not, commonly receive intravenous iron to control anemia. Finally, we unraveled the influence of age and sex on the complement system in healthy individuals. In conclusion, considering the link between complement activation and cardiovascular disease, targeting the complement system in CKD and dialysis is a potential strategy to improve outcome in these patients.

Published
2019

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