803 results on '"Meibohm, Bernd"'
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2. Contributors
3. Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer
4. Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates
5. Clinical and Translational Pharmacology Considerations for Anti-infectives Approved Under the FDA Animal Rule
6. TNX-1500, a crystallizable fragment–modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival
7. TNX-1500, a crystallizable fragment–modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival
8. Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes
9. Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections
10. SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis
11. Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer
12. Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis
13. A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides.
14. Translational modelling to predict human pharmacokinetics and pharmacodynamics of a Bruton's tyrosine kinase‐targeted protein degrader BGB‐16673.
15. Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction
16. Pharmacokinetics and Pharmacodynamics of Therapeutic Peptides and Proteins
17. A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides
18. The atypical antipsychotic aripiprazole alters the outcome of disseminatedCandida albicansinfections.
19. Time to ‘Mind the Gap’ in novel small molecule drug discovery for direct-acting antivirals for SARS-CoV-2
20. Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus
21. A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides
22. Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS
23. Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis
24. Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function
25. Enhancing the therapeutic window for Spectinamide anti-tuberculosis Agents: Synthesis, Evaluation, and activation of phosphate prodrug 3408
26. Disposable Dosators Intended for Dry Powder Delivery to Mice
27. Chapter 7: Pharmacology
28. Free Energy of Activation for the Comorosan Effect
29. Genetic variation in antioxidant enzymes, cigarette smoking, and longitudinal change in lung function
30. The influence of abdominal visceral fat on inflammatory pathways and mortality risk in obstructive lung disease
31. Cognitive Impairment and Medication Complexity in Community-Living Older Adults: The Health, Aging and Body Composition Study
32. Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study
33. Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics
34. The inducible prostaglandin E synthase (mPGES-1) in neuroinflammatory disorders
35. Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology?
36. Chapter 7: Pharmacology
37. The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360
38. Pharmacokinetics and Pharmacodynamics of Peptide and Protein Therapeutics
39. Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models
40. Supplementary Data from Colchicine-Binding Site Agent CH-2-77 as a Potent Tubulin Inhibitor Suppressing Triple-Negative Breast Cancer
41. Data from Colchicine-Binding Site Agent CH-2-77 as a Potent Tubulin Inhibitor Suppressing Triple-Negative Breast Cancer
42. Barriers to global pharmacometrics: educational challenges and opportunities across the globe
43. Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo
44. Novel, Brain-Permeable, Cross-Species Benzothiazole Inhibitors of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Dampen Neuroinflammation In Vitro and In Vivo
45. Translational PK/PD of anti-infective therapeutics
46. The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360
47. Chapter 7: Pharmacokinetics
48. Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis
49. Influence of Ethanol on Darunavir Hepatic Clearance and Intracellular PK/PD in HIV-Infected Monocytes, and CYP3A4-Darunavir Interactions Using Inhibition and in Silico Binding Studies
50. Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure
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