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105 results on '"Meier, PN"'

1. Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer

Author

Plentz, RR, Wiemann, SU, Flemming, P, Meier, PN, Kubicka, S, Kreipe, H, Manns, MP, and Rudolph, KL

Subjects
Epithelium -- Genetic aspects -- Physiological aspects -- Research -- Health aspects, Genetic markers -- Physiological aspects -- Research -- Genetic aspects -- Health aspects, Colorectal diseases -- Research -- Causes of -- Health aspects -- Care and treatment -- Genetic aspects, Colorectal cancer -- Health aspects -- Genetic aspects -- Care and treatment -- Causes of -- Research, Chromosomes -- Genetic aspects -- Physiological aspects -- Health aspects -- Research, Gastrointestinal diseases -- Research -- Causes of -- Health aspects -- Care and treatment -- Genetic aspects, Health, Care and treatment, Physiological aspects, Research, Genetic aspects, Causes of, Health aspects
Abstract

Background and aims: Chromosomal instability is one of the most consistent markers of sporadic colorectal cancer in humans. There is growing evidence that telomere shortening is one of the mechanisms [...]

Published
2003

17. ERCP Topics

Author

Meier Pn

Subjects
medicine.medical_specialty, Endoscopic retrograde cholangiopancreatography, medicine.diagnostic_test, business.industry, General surgery, Gastroenterology, Medicine, business
Published
2000

18. Aktuelle Therapie der primären sklerosierenden Cholangitis*

Author

M.P. Manns, Meier Pn, Wanger S, Nashan B, and Maschek H

Subjects
medicine.medical_specialty, business.industry, General surgery, Art therapy, medicine, General Medicine, medicine.disease, business, Primary sclerosing cholangitis
Published
2008

25. Das große Krabbeln!

Author

Wedemeyer, J, primary, Freise, J, additional, Hülsemann, JL, additional, Zeidler, H, additional, Manns, MP, additional, Krüger, M, additional, and Meier, PN, additional

Published
2006
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49. IgG4-related sclerosing cholangitis mimicking hilar cholangiocarcinoma (Klatskin tumor): a case report of a challenging disease and review of the literature.

Author

Mittelstaedt A, Meier PN, Dankoweit-Timpe E, Christ B, and Jaehne J

Abstract

Background: Even though IgG4-related disease has gained increased attention worldwide, the diagnosis remains challenging. IgG4-related sclerosing cholangitis (IgG4-SC) is not well described in the western hemisphere and may mimic cholangiocarcinoma (CC), especially when occurring without other symptoms such as, e.g. concurrent pancreatitis or retroperitoneal fibrosis. We present a case to add further information to the diagnosis and treatment of this challenging disease., Case Report: A 60-year-old male patient presented with painless jaundice. Prior medical history showed diabetes mellitus type I, high blood pressure, and deep vein thrombosis. Diagnostic investigations were strongly suspicious of a Klatskin tumor, although biopsies were inconclusive. The tumor marker Carbohydrate Antigen 19-9 (CA 19-9) was elevated. Prior to the recommended surgery, the patient had two second opinions in two different university hospitals, both arguing for surgery as well. The patient received hilar resection with right hemihepatectomy. During the postoperative course, some major complications occurred, i.e. recurrent pleural effusion, abscess in the liver resection area, sepsis, ileus, and restricted liver metabolism. Treatment with prednisolone did not show any improvement. Approximately 3 months after surgery, the patient died in consequence of acute respiratory failure. Histology showed no signs of CC, but IgG4-SC could be diagnosed., Conclusion: In the case of preoperative signs of CC, differential diagnosis of IgG4-SC needs to be considered, in particular, in cases with missing histologic proof of malignant disease., (©2018 Mittelstaedt A., et al., published by De Gruyter, Berlin/Boston.)

Published
2018
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50. Update in Natural Orifice Translumenal Endoscopic Surgery (NOTES).

Author

Bernhardt J, Sasse S, Ludwig K, and Meier PN

Subjects
Cholecystectomy instrumentation, Cholecystectomy trends, Humans, Operative Time, Patient Selection, Thyroidectomy instrumentation, Thyroidectomy trends, Cholecystectomy methods, Laparoscopy trends, Natural Orifice Endoscopic Surgery trends, Thyroidectomy methods
Abstract

Purpose of Review: The recent developments and clinical applications of natural orifice translumenal endoscopic surgery (NOTES)-procedures and technologies are going to be presented., Recent Findings: In experimental as well as clinical settings, NOTES-procedures are predominantly performed in hybrid technique. Current experimental studies focus on the implementation of new surgical approaches as well as on the training of procedures. One emphasis in the clinical application is transrectal and transanal interventions. Transanal total mesorectal excision is equivalent to laparoscopic procedures but with the benefit of an even less invasive access. Transvaginal cholecystectomy can achieve results that are comparable to surgeries that are performed with laparoscopic techniques alone. An analysis of the German NOTES-Register concerning appendectomies as well as the national performance of NOTES-interventions in Switzerland is presented. Apart from intraabdominal approaches, several centers proclaim transoral thyroidectomies and transoral mediastinoscopies., Summary: NOTES-procedures are performed in animal experiments as well as in clinical setting although with less frequency. At this time, hybrid techniques using rigid instruments are mainly applied.

Published
2017
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