1. Renal Cell Cancer Syndromes: Identification and Management of Patients and Families at Increased Risk
- Author
-
Tracy Fasolino and Melissa Paquin
- Subjects
business.industry ,Syndrome ,Bioinformatics ,Kidney Neoplasms ,Increased risk ,Neoplastic Syndromes, Hereditary ,Mutation ,Mutation (genetic algorithm) ,Humans ,General Earth and Planetary Sciences ,Medicine ,Genetic Predisposition to Disease ,Cell cancer ,Identification (biology) ,Genetic Testing ,Age of onset ,business ,Carcinoma, Renal Cell ,Relevant information ,Aged ,General Environmental Science - Abstract
There are many inherited renal cell cancer syndromes that increase an individual's risk of developing renal cell cancer. The age of onset for these renal cell cancer syndromes ranges from infancy to age 65 years. Clinical manifestations vary widely, and multiple body systems can be involved and present unique challenges to the healthcare team. With the advancement of genetic panels, clinicians can screen individuals with known hereditary syndromes for genetic mutations. This article offers clinically relevant information specific to various major renal cell cancer syndromes.
- Published
- 2020
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