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39 results on '"Melton, Sherry M"'

1. Abnormalities of laboratory coagulation tests versus clinically evident coagulopathic bleeding: results from the prehospital resuscitation on helicopters study (PROHS)

Author

Holcomb, John B., Wade, Charles E., Fox, Erin E., Chang, Ronald, Podbielski, Jeanette M., Tomasek, Jeffrey S., del Junco, Deborah J., Swartz, Michael D., DeSantis, Stacia M., Appana, Savitri N., Greene, Thomas J., Yi, Misung, Gonzalez, Michael O., Baraniuk, Sarah, van Belle, Gerald, Leroux, Brian G., Howard, Carrie L., Haymaker, Amanda, Stein, Deborah M., Scalea, Thomas M., Ayd, Benjamin, Das, Pratik, Herrera, Anthony V., Bulger, Eileen M., Robinson, Bryce R.H., Klotz, Patricia, Minhas, Aniqa, Kerby, Jeffrey D., Melton, Sherry M., Williams, Carolyn R., Stephens, Shannon W., Goodman, Michael, Johannigman, Jay A., McMullan, Jason, Branson, Richard D., Gomaa, Dina, Barczak, Christopher, Schreiber, Martin A., Underwood, Samantha J., Watson, Cheri, Zielinski, Martin D., Stubbs, James R., Headlee, Amy, O'Keeffe, Terence, Rhee, Peter, Rokowski, Laurel L., Santoro, John, Jr, Seach, Andrea, Bradford, David, Fealk, Michelle, Latifi, Fortesa, Inaba, Kenji, Kim, Henry, Chudnofsky, Carl, Wong, Monica D., Goodman, Michael D., Appana, Savitri, Johansson, Pär I., Henriksen, Hanne H., Stensballe, Jakob, and Steinmetz, Jacob

Published
2018
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10. Abnormalities of laboratory coagulation tests versus clinically evident coagulopathic bleeding: results from the prehospital resuscitation on helicopters study (PROHS)

Author

Chang, Ronald, primary, Fox, Erin E., additional, Greene, Thomas J., additional, Swartz, Michael D., additional, DeSantis, Stacia M., additional, Stein, Deborah M., additional, Bulger, Eileen M., additional, Melton, Sherry M., additional, Goodman, Michael D., additional, Schreiber, Martin A., additional, Zielinski, Martin D., additional, O'Keeffe, Terence, additional, Inaba, Kenji, additional, Tomasek, Jeffrey S., additional, Podbielski, Jeanette M., additional, Appana, Savitri, additional, Yi, Misung, additional, Johansson, Pär I., additional, Henriksen, Hanne H., additional, Stensballe, Jakob, additional, Steinmetz, Jacob, additional, Wade, Charles E., additional, Holcomb, John B., additional, Chang, Ronald, additional, del Junco, Deborah J., additional, Appana, Savitri N., additional, Gonzalez, Michael O., additional, Baraniuk, Sarah, additional, van Belle, Gerald, additional, Leroux, Brian G., additional, Howard, Carrie L., additional, Haymaker, Amanda, additional, Scalea, Thomas M., additional, Ayd, Benjamin, additional, Das, Pratik, additional, Herrera, Anthony V., additional, Robinson, Bryce R.H., additional, Klotz, Patricia, additional, Minhas, Aniqa, additional, Kerby, Jeffrey D., additional, Williams, Carolyn R., additional, Stephens, Shannon W., additional, Goodman, Michael, additional, Johannigman, Jay A., additional, McMullan, Jason, additional, Branson, Richard D., additional, Gomaa, Dina, additional, Barczak, Christopher, additional, Underwood, Samantha J., additional, Watson, Cheri, additional, Stubbs, James R., additional, Headlee, Amy, additional, Rhee, Peter, additional, Rokowski, Laurel L., additional, Santoro, John, additional, Seach, Andrea, additional, Bradford, David, additional, Fealk, Michelle, additional, Latifi, Fortesa, additional, Kim, Henry, additional, Chudnofsky, Carl, additional, and Wong, Monica D., additional

Published
2018
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11. Abnormalities of laboratory coagulation tests versus clinically evident coagulopathic bleeding:results from the prehospital resuscitation on helicopters study (PROHS)

Author

Chang, Ronald, Fox, Erin E, Greene, Thomas J, Swartz, Michael D, DeSantis, Stacia M, Stein, Deborah M, Bulger, Eileen M, Melton, Sherry M, Goodman, Michael D, Schreiber, Martin A, Zielinski, Martin D, O'Keeffe, Terence, Inaba, Kenji, Tomasek, Jeffrey S, Podbielski, Jeanette M, Appana, Savitri, Yi, Misung, Johansson, Pär I, Henriksen, Hanne H, Stensballe, Jakob, Steinmetz, Jacob, Wade, Charles E, Holcomb, John B, Chang, Ronald, Fox, Erin E, Greene, Thomas J, Swartz, Michael D, DeSantis, Stacia M, Stein, Deborah M, Bulger, Eileen M, Melton, Sherry M, Goodman, Michael D, Schreiber, Martin A, Zielinski, Martin D, O'Keeffe, Terence, Inaba, Kenji, Tomasek, Jeffrey S, Podbielski, Jeanette M, Appana, Savitri, Yi, Misung, Johansson, Pär I, Henriksen, Hanne H, Stensballe, Jakob, Steinmetz, Jacob, Wade, Charles E, and Holcomb, John B

Abstract

BACKGROUND: Laboratory-based evidence of coagulopathy (LC) is observed in 25-35% of trauma patients, but clinically-evident coagulopathy (CC) is not well described.METHODS: Prospective observational study of adult trauma patients transported by helicopter from the scene to nine Level 1 trauma centers in 2015. Patients meeting predefined highest-risk criteria were divided into CC+ (predefined as surgeon-confirmed bleeding from uninjured sites or injured sites not controllable by sutures) or CC-. We used a mixed-effects, Poisson regression with robust error variance to test the hypothesis that abnormalities on rapid thrombelastography (r-TEG) and international normalized ratio (INR) were independently associated with CC+.RESULTS: Of 1,019 highest-risk patients, CC+ (n=41, 4%) were more severely injured (median ISS 32 vs 17), had evidence of LC on r-TEG and INR, received more transfused blood products at 4 hours (37 vs 0 units), and had greater 30-day mortality (59% vs 12%) than CC- (n=978, 96%). The overall incidence of LC was 39%. 30-day mortality was 22% vs 9% in those with and without LC. In two separate models, r-TEG K-time >2.5 min (RR 1.3, 95% CI 1.1-1.7), r-TEG mA <55 mm (RR 2.5, 95% CI 2.0-3.2), platelet count <150 x 109/L (RR 1.2, 95% CI 1.1-1.3), and INR >1.5 (RR 5.4, 95% CI 1.8-16.3) were independently associated with CC+. A combined regression model was not generated because too few patients underwent both r-TEG and INR.CONCLUSION: CC was rare compared to LC. CC was associated with poor outcomes and impairment of both clotting factor and platelet-mediated coagulation components.

Published
2018

22. The Evolution of Chest Computed Tomography for the Definitive Diagnosis of Blunt Aortic Injury: A Single-Center Experience

Author

Melton, Sherry M., primary, Kerby, Jeffrey D., additional, McGiffin, David, additional, McGwin, Gerald, additional, Smith, J. Kevin, additional, Oser, Rachel F., additional, Cross, James M., additional, Windham, Samuel T., additional, Moran, Stephan G., additional, Hsia, Jennifer, additional, and Rue, Loring W., additional

Published
2004
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33. Prospective Study of Blunt Aortic Injury

Author

Fabian, Timothy C., primary, Davis, Kimberly A., additional, Gavant, Morris L., additional, Croce, Martin A., additional, Melton, Sherry M., additional, Patton, Joe H., additional, Haan, Constance K., additional, Weiman, Darryl S., additional, and Pate, James W., additional

Published
1998
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35. Popliteal Artery Trauma

Author

Melton, Sherry M., primary, Croce, Martin A., additional, Patton, Joe H., additional, Pritchard, F. Elizabeth, additional, Minard, Gayle, additional, Kudsk, Kenneth A., additional, and Fabian, Timothy C., additional

Published
1997
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36. Endovascular Repair of a Traumatic Infrarenal Aortic Transection.

Author

Voellinger, David C., Saddakni, Souheil, Melton, Sherry M., Wirthlin, Douglas J., Jordan, William D., and Whitley, David

Abstract

Blunt abdominal aortic trauma occurs in up to 0.04% of all nonpenetrating traumas. Although uncommon, mortality from this injury ranges from 18% to 37%. Seat belt injury is associated with almost 50% of reported blunt abdominal aortic traumas. The authors present the case of a 21-year-old man, a restrained passenger who was involved in a high-speed motor vehicle accident. In the emergency room, he had obvious evidence of lap-belt injury. His peripheral pulses were normal and there was no pulsatile abdominal mass. Computer tomography (CT) revealed a large amount of free intraperitoneal fluid throughout with signs of mesenteric avulsion and fracture/dislocation of T11-T12. The patient underwent an exploratory laparotomy. Right hemicolectomy and resection of small bowel was performed. CT angiography revealed an aortic transection and surrounding pseudoaneurysm 2 cm above the aortic bifurcation. The patient returned to the operating room for endovascular repair. Via a right femoral cutdown, a 14 mm x 5.5 cm stent-graft was placed across the distal abdominal aorta. Followup arteriogram revealed complete obliteration of the pseudoaneurysm without evidence of leak. There were no complications related to the aortic stent-graft in the postoperative period. The patient was discharged in good condition. As this case demonstrates, endovascular repair of traumatic aortic injury is feasible and may represent an improved treatment in certain settings. [ABSTRACT FROM PUBLISHER]

Published
2001
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37. REDUCTION OF VANCOMYCINRESISTANT ENTEROCOCCAL INFECTIONS BY LIMITATION OF BROADSPECTRUM CEPHALOSPORIN USE IN A TRAUMA AND BURN INTENSIVE CARE UNIT

Author

May, Addison K., Melton, Sherry M., McGwin, Gerald, Cross, James M., Moser, Stephen A., and Rue, Loring W.

Abstract

Both vancomycin and thirdgeneration cephalosporin use are believed to contribute to a rise in vancomycinresistant enterococci VRE infections. In 1998, the largest number of VRE infections in our hospital occurred in the traumaburn intensive care unit TBICU, accounting for nearly 20 of hospital infections. In an attempt to control the VRE infection rate, antibiotic protocols for prophylaxis, empiric, and definitive therapy were initiated during the final quarter of 1998 to minimize cephalosporin use by the introduction of piperacillintazobactam. Therefore, we undertook a study of the VRE infection rate for the TBICU in relation to vancomycin, piperacillintazobactam, piperacillin, thirdgeneration cephalosporin, and total cephalosporin use before and after efforts to limit cephalosporins. These data were compared to those in the medical and surgical intensive care units. During 1998, seven VRE infections occurred in the TBICU. Following initiation of antibiotic protocols, one case of VRE infection occurred in the subsequent month and no cases in the 17 months since. The decrease in the VRE infection rate corresponded with a significant increase in the use of piperacillintazobactam and a reduction in thirdgeneration and total cephalosporin use. In contrast, cephalosporin use in the medical and surgical intensive care units remains significantly higher than in the TBICU, and neither unit has had a reduction in their VRE infection rates.

Published
2000

38. Some Biomechanical Considerations of Polytetrafluoroethylene Sutures

Author

Dang, Minh-Chau, Thacker, John G., Hwang, Jim C-S, Rodeheaver, George T., Melton, Sherry M., and Edlich, Richard F.

Abstract

• The biomechanical performance of polytetrafluoroethylene (PTFE) sutures has been compared with that of polypropylene sutures, the standard to which other sutures used in vascular and cardiac surgery are compared. The PTFE is supple and has no plastic memory, while the polypropylene suture is stiff and retains its plastic memory. In addition, the rate of creep encountered in the PTFE suture was significantly less than that of the polypropylene suture. The knotting profiles for knot security for either a square, granny, or surgeon's knot for polypropylene sutures were three throws each. In contrast, knot security with either a square or granny PTFE knot was accomplished with seven throws; six throws were needed for a secure surgeon's knot. The breaking strength of the unknotted and knotted PTFE sutures was approximately one half as great as that for the unknotted and knotted polypropylene sutures. Knot construction significantly reduced the breaking strength of polypropylene sutures but did not alter the breaking strength of PTFE sutures. The percent elongation experienced by both sutures before breakage did not differ significantly. The elasticity, as measured by work recovery, for the polypropylene suture was greater than that for the PTFE suture. On the basis of its unique biomechanical performance characteristics, the PTFE suture should have an important place in vascular and cardiac surgery.(Arch Surg. 1990;125:647-650)

Published
1990
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39. Motor vehicle crash-related mortality is associated with prehospital and hospital-based resource availability.

Author

Melton SM, McGwin G Jr, Abernathy JH 3rd, MacLennan P, Cross JM, and Rue LW 3rd

Subjects
Accidents, Traffic statistics & numerical data, Alabama, Humans, Income, Rural Population, Urban Population, Accidents, Traffic mortality, Emergency Medical Services statistics & numerical data, Emergency Service, Hospital statistics & numerical data, Population Surveillance
Abstract

Background: To date, attempts to assess the relationship between motor vehicle collision (MVC)-related mortality and medical resources availability have largely been unsuccessful., Methods: Information regarding sociodemographic characteristics, prehospital resources, and hospital-based resources for each county (n = 67) in the state of Alabama was obtained. MVC-related mortality rates (deaths per 1,000 collisions) by county were calculated and compared according to prehospital and hospital-based resource availability within each county after correcting for sociodemographic factors., Results: Counties with 24-hour availability of a general surgeon, orthopedic surgeon, neurosurgeon, computed tomographic scanner, and operating room were shown to have decreased MVC-related mortality (relative risk [RR], 0.88). The same was true for those counties with hospitals classified as Level I-II (RR, 0.71) and Level III-IV (RR, 0.83) trauma centers compared with counties with no trauma centers., Conclusion: Appropriate, readily available hospital-based resources are associated with lower MVC-related mortality rates. This information may be useful in trauma system planning and development.

Published
2003
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