Search

Recently, frequent water shortages and reductions in water flow have been observed in the northern segment of the Yellow River within the Beijing–Hangzhou Grand Canal. In response, a water replenishment program has been initiated. This study is focused on the section of the Grand Canal north of the Yellow River and uses the GSFLOW model to examine interaction between surface water and groundwater, as well as the effect of water replenishment. The results indicate that, after the water replenishment, the efficiency of water replenishment was highest in the Xiao Canal (64.30%), followed by the Wei Canal (39.09%), the South Canal (12.11%), and the North Canal, which exhibited the lowest efficiency (5.75%). This variation can be attributed to greater water loss with increasing distance from the replenishment source, leading to lower replenishment efficiency. Surface water recharge to groundwater was extended by 32 days, with replenishment effects persisting even after the water supply ceased. The maximum influence distance on either side of the canal reached 5.73 km, with an average impact distance of 1.48 km, resulting in a total affected area of 974.7 km2, accounting for 2.2% of the study area. Water replenishment positively influenced the recovery of groundwater levels along the Grand Canal. [ABSTRACT FROM AUTHOR]

Peng Shuzhi is a famous historian of Asian and African studies in China. His research methods are embodied in his book Thought of the Oriental Nationalism, in which he lays emphasis on two approaches: scientific taste and matter-of-fact attitude. The former helps him choose the Oriental Nationalism as his research subject, and the latter helps him make some well-founded new findings. The combination of the two approaches drives the research into a new level of broadening our minds and showing great foresight. [ABSTRACT FROM AUTHOR]

We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms (SNPs). This map is based on a comparison of the sequences of three domestic chicken breeds (a broiler, a layer and a Chinese silkie) with that of their wild ancestor, red jungle fowl. Subsequent experiments indicate that at least 90% of the variant sites are true SNPs, and at least 70% are common SNPs that segregate in many domestic breeds. Mean nucleotide diversity is about five SNPs per kilobase for almost every possible comparison between red jungle fowl and domestic lines, between two different domestic lines, and within domestic lines-in contrast to the notion that domestic animals are highly inbred relative to their wild ancestors. In fact, most of the SNPs originated before domestication, and there is little evidence of selective sweeps for adaptive alleles on length scales greater than 100?kilobases. [ABSTRACT FROM AUTHOR]

Sorafenib is a new multi-target oral drug that inhibits many kinds of protein kinase small molecules to treat tumors. Currently, sorafenib is one of the drugs that permit systemic treatment of liver cancer in the middle stage. Although sorafenib has good therapeutic effect on liver cancer, the clinical effect of sorafenib alone in the treatment of liver cancer is limited. This study compared the efficacy of sorafenib, TACE (transcatheter arterial chemoembolization), and sorafenib combined with TACE in the treatment of liver cancer patients. The results showed that the curative effect of sorafenib combined with transcatheter arterial chemoembolization is better than that of hepatic artery chemoembolization or sorafenib orally. The total effective rate of combined treatment is 93.8%, while the effective rate of arterial chemoembolization and sorafenib is 64.1% and 72.2% respectively. Combined treatment can significantly prolong the total survival of the patients with liver cancer, which is significantly different from that of arterial chemoembolization or sorafenib alone.