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583 results on '"Meng Guangyao"'

1. Dynamics Analysis of a Special Differential Gear Transmission System

Author

Kong Guang, Meng Guangyao, Wang Zuojuan, Huang Juxin, and Li Zhongzheng

Subjects
Special differential, Incentive factor, Phase path, Mechanical engineering and machinery, TJ1-1570
Abstract

The dynamics analysis of a special rotating differential which situating to the variable tread vehicle steering function is carried out. Firstly,treating this differential gear transmission system as spring-mass of the nonlinear time-varying system with coulomb damping,a bend-torsion coupled vibration model with 12 DOFs is established. Then,considering the road to the wheel load torque in the process of the corners to be external incentive conditions of system,the affect of internal incentive factors on vibration characteristics of this differential gear transmission system is analyzed and the dynamics mathematical model is built. At last,by calculating this mathematical model and natural frequency,the phase path analysis is carried out and the characteristic parameters of this gear transmission system are optimized. The purpose of weakening the oscillation of the system performance and improving the response speed of system,making the system with satisfactory dynamic performance indicators are achieved.

Published
2017
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7. Transcriptome-Wide Study of mRNAs and lncRNAs Modified by m6A RNA Methylation in the Longissimus Dorsi Muscle Development of Cattle-Yak

Author

Huang, Chun, primary, Dai, Rongfeng, additional, Meng, Guangyao, additional, Dingkao, Renqing, additional, Wang, Xingdong, additional, Ren, Wenwen, additional, Ma, Xiaoming, additional, Wu, Xiaoyun, additional, Chu, Min, additional, La, Yongfu, additional, Bao, Pengjia, additional, Guo, Xian, additional, Pei, Jie, additional, Yan, Ping, additional, and Liang, Chunnian, additional

Published
2022
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46. Transcriptome-Wide Study of mRNAs and lncRNAs Modified by m 6 A RNA Methylation in the Longissimus Dorsi Muscle Development of Cattle-Yak.

Author

Huang, Chun, Dai, Rongfeng, Meng, Guangyao, Dingkao, Renqing, Wang, Xingdong, Ren, Wenwen, Ma, Xiaoming, Wu, Xiaoyun, Chu, Min, La, Yongfu, Bao, Pengjia, Guo, Xian, Pei, Jie, Yan, Ping, and Liang, Chunnian

Subjects
MUSCLE growth, RNA methylation, LINCRNA, ERECTOR spinae muscles, GENE expression
Abstract

Cattle-yak is a hybrid F1 generation of cattle and yak, which has a history of more than 3000 years and has shown better production performance and higher economic benefits than those of yaks. However, up to now, there has been no study on the transcriptome-wide m6A methylation profile of bovine skeletal muscle and its potential biological function during muscle development. Here, we observed significant changes in the expression levels of muscle-related marker genes and methylation-related enzymes during the development of cattle-yak, and the overall m6A content in the Longissimus dorsi muscle of 18-month-old cattle-yak decreased significantly. A total of 36,602 peaks, 11,223 genes and 8388 lncRNAs were identified in the two groups, including 2989 differential peaks (427 up-regulated peaks and 2562 down-regulated peaks), 1457 differentially expressed genes (833 up-regulated genes and 624 down-regulated genes) and 857 differentially expressed lncRNAs (293 up-regulated lncRNAs and 564 down-regulated lncRNAs). GO and KEGG analysis revealed that they were significantly enriched in some muscle-related pathways (Wnt signaling pathway and MAPK signaling pathway) and high-altitude adaptation-related pathway (HIF-1 signaling pathway). Moreover, m6A abundance was positively correlated with gene expression levels, while it was negatively correlated with lncRNA expression levels. This indicates that m6A modification played an important role in the Longissimus dorsi muscle development of cattle-yak; however, the regulation mechanism of m6A-modified mRNA and lncRNA may be different. This study was the first report of transcriptome-wide m6A-modified mRNAs and lncRNAs atlas in the Longissimus dorsi muscle development of cattle-yak, one which will provide new perspectives for genetic improvement in bovines. [ABSTRACT FROM AUTHOR]

Published
2022
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