19 results on '"Mengnan Huang"'
Search Results
2. Triglyceride glucose index for the detection of the severity of coronary artery disease in different glucose metabolic states in patients with coronary heart disease: a RCSCD-TCM study in China
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Jinyu Su, Zhu Li, Mengnan Huang, Yang Wang, Tong Yang, Mei Ma, Tongyao Ni, Guangwei Pan, Ziqin Lai, Chunjie Li, Lin Li, and Chunquan Yu
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Coronary heart disease ,Coronary artery disease severity ,Triglyceride glucose index ,Glucose metabolic states ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Triglyceride glucose (TyG) index is a new marker associated with atherosclerosis. This study aimed to assess the association between TyG index and the severity of coronary artery disease (CAD) in patients with coronary heart disease (CHD) and further explore the association between TyG index and CAD severity in different glucose metabolic states. Methods This multi-centre retrospective study included 731 patients with CHD between January 1, 2014 and September 30, 2020 in China. All patients were stratified into groups based on the tertiles of TyG index (T1: 5.48 ≤ TyG index ≤ 7.17; T2: 7.18 ≤ TyG index ≤ 7.76; T3: 7.77 ≤ TyG index ≤ 10.82). The number of diseased vessels [single-vessel and multi-vessel CAD (≥ 50% stenosis in ≥ 2 large vessels)] represented the severity of CAD, which was measured using coronary angiography (CAG). Glucose metabolic states were defined by the American Diabetes Association as normal glucose regulation (NGR), prediabetes mellitus (Pre-DM), and diabetes mellitus (DM). Results The baseline analysis results showed significant differences in the clinical and biological characteristics of CHD patients according to TyG index tertiles (P more...
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- 2022
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3. Low−/high-density lipoprotein cholesterol ratio and carotid plaques in patients with coronary heart disease: a Chinese cohort study
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Zhu Li, Qi Cheng, Yijia Liu, Xufeng Cheng, Shuo Wang, Yuanyuan He, Xu Wang, Mengnan Huang, Yue Li, Xiaoxue Xue, Yilan Xu, Lin Li, Yanchao Zheng, Rongrong Yang, Shan Gao, and Chunquan Yu
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Coronary heart disease ,Carotid plaques ,LDL-C/HDL-C ,Healthy lifestyle ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Background Evidence on the relationship between the low−/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) and carotid plaques remains limited. This study aimed to examine the association between LDL-C/HDL-C and carotid plaques in participants with coronary heart disease (CHD) and to further explore the extent to which a healthy lifestyle reduces the risk of LDL-C/HDL-C-related carotid plaques. Methods This large-scale and multi-centre retrospective study included 9426 CHD patients (aged 35–75 years) between January 1, 2014 and September 30, 2020. The LDL-C/HDL-C values were converted to the following tertiles: lowest ( 3). Healthy lifestyle-related factors referred to whether or not the participant was a non-smoker and non-drinker. Participants were divided into an unfavourable group (those who did not adhere to healthy lifestyle factors), intermediate (only one unhealthy factor), and favourable (neither of the two unhealthy factors). Logistic regression was used for statistical analyses. Results Of the 9426 participants, 6989 (74.15%) CHD patients had carotid plaques. After adjustment for confounders, each unit increase in the LDL-C/HDL-C was significantly associated with carotid plaques (OR: 1.61; 95%CI: 1.43–1.84; P 3) was 1.18 times that of the lowest quartile ( more...
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- 2021
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4. Association of Serum γ-Glutamyltransferase With C-Reactive Protein Levels in Patients With Coronary Heart Disease
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Yuanyuan He, Mengnan Huang, Zhu Li, Qi Cheng, Yijia Liu, Xiaoxue Xue, Yilan Xu, Yanchao Zheng, Lin Li, Shan Gao, and Chunquan Yu
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Cardiology and Cardiovascular Medicine - Abstract
Serum γ-glutamyltransferase (GGT) levels have been shown to be associated with C-reactive protein (CRP) levels. Nevertheless, studies on this relationship in coronary heart disease (CHD) populations are limited. This study retrospectively assessed 17 523 patients with CHD undergoing GGT and CRP testing. They were divided into 3 groups according to GGT tertiles. The critical points for high CRP levels was 10.0 mg/L, which corresponded to the 75th percentile. Logistic regression analysis was used to analyze the association between GGT and CRP levels in CHD patients. The baseline analysis showed significant differences in related parameters among patients with CHD. Compared with GGT tertile 1 (T1), the odds ratio (OR) of T3 for GGT in CHD patients was 2.15 (95% confidence interval [CI]: 1.96–2.36). The association between GGT and CRP was higher in males (OR: 2.23; 95% CI: 1.98–2.52) than in females (OR: 2.18; 95% CI: 1.89–2.51). This study showed an association between serum GGT and CRP levels in patients with CHD. GGT may be an inflammatory marker and an additional measure for assessing cardiovascular risk. more...
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- 2022
5. CTAB assisted evaporation-induced self-assembly to construct imidazolium-based hierarchical porous covalent organic polymers for ReO4-/TcO4- removal
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Yuejiao Wang, Mengnan Huang, Haibiao Yu, Junshuo Cui, Jing Gao, Zhenning Lou, Xiaogeng Feng, Weijun Shan, and Ying Xiong
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Environmental Engineering ,Health, Toxicology and Mutagenesis ,Environmental Chemistry ,Pollution ,Waste Management and Disposal - Published
- 2023
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6. Efficient and selective capture of uranium by polyethyleneimine-modified chitosan composite microspheres from radioactive nuclear waste
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Mengnan Huang, Lisha Xie, Yuejiao Wang, Xiaogeng Feng, Jing Gao, Zhenning Lou, and Ying Xiong
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Chitosan ,Kinetics ,Health, Toxicology and Mutagenesis ,Radioactive Waste ,Uranium ,Polyethyleneimine ,General Medicine ,Adsorption ,Wastewater ,Hydrogen-Ion Concentration ,Toxicology ,Pollution ,Microspheres - Abstract
Uranium extraction from radioactive nuclear waste is vital for sustainable energy supply and ecological security. Herein, a polyethyleneimine-chitosan composite microspheres n-PEI/ECH-CTS (n = 0.1, 0.2, 0.3, 0.4, 0.5) were synthetized for efficient and selective uranium adsorption. The prepared chitosan microspheres with uniform size, uniform dispersion and good mechanical strength combine cost-effectiveness and environmental benefits. The 0.4-PEI/ECH-CTS exhibits the highest adsorption capacity of 380.65 mg g more...
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- 2022
7. One-step cross-linking of amino-rich chitosan aerogels for efficient and selective adsorption of uranium from radioactive nuclear wastewater
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Mengnan Huang, Shiying Fan, Lisha Xie, Junshuo Cui, Weijun Shan, Zhenning Lou, and Ying Xiong
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Filtration and Separation ,Analytical Chemistry - Published
- 2023
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8. Association Between Anemia Status and the Risk of Different Types of Heart Failure: A RCSCD-TCM Study in China
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Tongyao Ni, Yijia Liu, Mengnan Huang, Mei Ma, Lin Li, Chunjie Li, Rongrong Yang, and Chunquan Yu
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Cardiology and Cardiovascular Medicine - Abstract
We investigated the association between anemia status and the risk of heart failure (HF) in patients with coronary heart disease (CHD) based on a multi-center, large-sample and retrospective cross-sectional study including 89,207 patients. Heart failure was categorized as HF with reduced ejection fraction (HFrEF), HF with preserved ejection fraction (HFpEF), and HF with mid-range ejection fraction (HFmrEF). In multi-adjusted models, compared with patients without anemia, mild anemia (odds ratio [OR] 1.71; 95% confidence interval [CI] 1.53–1.91; P < .001), moderate anemia (OR 3.68; 95% CI, 3.25–4.17; P < .001), and severe anemia (OR 8.02; 95% CI, 6.50–9.88; P < .001) were associated with the risk of HF among CHD patients. Men aged more...
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- 2023
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9. Efficient uranium electrochemical deposition with a functional phytic Acid-Doped Polyaniline/Graphite sheet electrode by Adsorption-electrodeposition strategy
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Mengnan Huang, Lisha Xie, Yuejiao Wang, Hongjiang He, Haibiao Yu, Junshuo Cui, Xiaogeng Feng, Zhenning Lou, and Ying Xiong
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General Chemical Engineering ,Environmental Chemistry ,General Chemistry ,Industrial and Manufacturing Engineering - Published
- 2023
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10. Acrylic Acid-Functionalized Metal–Organic Frameworks for Sc(III) Selective Adsorption
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Zhenning Lou, Mengnan Huang, Xin Xiao, Zhiqiang Xing, Ying Xiong, and Yuejiao Wang
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Langmuir ,Materials science ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry.chemical_compound ,Adsorption ,X-ray photoelectron spectroscopy ,chemistry ,Selective adsorption ,General Materials Science ,Metal-organic framework ,Titration ,Fourier transform infrared spectroscopy ,0210 nano-technology ,Acrylic acid ,Nuclear chemistry - Abstract
The increasing demand for rare-earth elements (REEs) due to their extensive high-tech applications has encouraged the development of new sustainable approaches for REE recovery and separation. In this work, a series of acrylic acid-functionalized metal–organic framework materials (named as y-AA-x@MIL-101s) were prepared and used for selective adsorption of Sc(III). The adsorbent was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, nitrogen adsorption, X-ray photoelectron spectroscopy, and zeta potential and surface functional-group titration. The adsorption isotherm and kinetics data were accurately described by the Langmuir and pseudo-second-order models. The adsorption capacity of the material for Sc(III), Nd(III), Gd(III), and Er(III) was 90.21, 104.59, 58.29, and 74.94 mg g–1, respectively. Importantly, the adsorbent was better for selective recovery of Sc(III) not only from the 16 REE mixed system but also the Cu(II), Zn(II), Mn(II), Co(II), a... more...
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- 2019
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11. LDL-C/HDL-C and carotid plaques in patients with coronary heart disease: A Chinese cohort study
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Yilan Xu, Rongrong Yang, Lin Li, Xu Wang, Yanchao Zheng, Xufeng Cheng, Mengnan Huang, Yuanyuan He, Qi Cheng, Yijia Liu, Yue Li, Xiaoxue Xue, Zhu Li, Shuo Wang, Shan Gao, and Chunquan Yu
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medicine.medical_specialty ,Text mining ,business.industry ,Internal medicine ,Cardiology ,Medicine ,lipids (amino acids, peptides, and proteins) ,In patient ,business ,Coronary heart disease ,Cohort study - Abstract
Background: Evidence of the association the low-/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) with the carotid plaques remains limited. The purpose of this study is to examine the association between LDL-C/HDL-C and carotid plaques of coronary heart disease (CHD), and to study what extent a healthy lifestyle reduces the risk of carotid plaques.Methods: In this large-scale and multi-center retrospective study, a total of 9,426 participants to explore the association between LDL-C/HDL-C and carotid plaques. No smoking and no drinking were considered healthy lifestyle. Generalised estimating equation models and conditional logistic regressions were used in statistical analyses.Results: In all the 9,426 participants, there were 6,989 (74.15%) patients having identified carotid plaques. High levels of LDL-C/HDL-C had a higher risk of carotid plaques than other lipid variables (OR:1.63; 95%CI:1.43-1.86). In stratified analyses by LDL-C/HDL-C triplet, participants in the LDL-C/HDL-C (>3mmol/L) group had a higher risk of carotid plaques compared to other two groups. Compared with the unfavourable lifestyle, intermediate lifestyle or favourable lifestyle was associated with a significant 30% or 67% decrease in carotid plaques risk among patients with the LDL-C/HDL-C(>3mmol/L) respectively. There were significantly additive and multiplicative interactions between lifestyle and LDL-C/HDL-C on carotid plaques.Conclusion: Our findings provide evidence that a high level of LDL-C/HDL-C can increase the risk of carotid plaques in patients with CHD. And adhering to a healthy lifestyle has additive beneficial effects on reducing the risk of carotid plaques. more...
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- 2021
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12. Immersion grinding and in-situ polymerization synthesis of poly(ionic liquid)s incorporation into MOF composites as radioactive TcO
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Mengnan, Huang, Zhenning, Lou, Wenyan, Zhao, Anping, Lu, Xiaomai, Hao, Yuejiao, Wang, Xiaogeng, Feng, Weijun, Shan, and Ying, Xiong
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Imidazolium-based ionic liquids (ILs) are a promising candidate for efficient separation of radioactive pertechnetate (TcO
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- 2021
13. Immersion grinding and in-situ polymerization synthesis of poly(ionic liquid)s incorporation into MOF composites as radioactive TcO4- scavenger
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Mengnan Huang, Yuejiao Wang, Wenyan Zhao, Xiaogeng Feng, Weijun Shan, Anping Lu, Ying Xiong, Zhenning Lou, and Xiaomai Hao
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Environmental Engineering ,Materials science ,Health, Toxicology and Mutagenesis ,Environmental pollution ,Pollution ,Gibbs free energy ,symbols.namesake ,chemistry.chemical_compound ,Adsorption ,Chemical engineering ,chemistry ,Polymerization ,Selective adsorption ,Ionic liquid ,symbols ,Environmental Chemistry ,Metal-organic framework ,In situ polymerization ,Waste Management and Disposal - Abstract
Imidazolium-based ionic liquids (ILs) are a promising candidate for efficient separation of radioactive pertechnetate (TcO4-) from nuclear waste. However, their effective fixation, availability of active sites and slow adsorption kinetics remain challenges. Here, we incorporated the bisimidazolium-based ILs into porous metal-organic frameworks (MOFs) via a combination of immersion grinding and in-situ polymerization. 3,3′-divinyl-1,1′(1,4-butanediyl) diimidazolium dichloride is tightly bound inside and outside the porous MOFs matrix by uniform immersion grinding, which facilitates the exposure of more adsorption sites and provides channels for the anions to travel through quickly. Solvent-free polymerization reduces environmental pollution and energy consumption. Notably, the composite P[C4(VIM)2]Cl2@MIL-101 possesses an admirable removal efficiency (673 mg g−1) compared with the pristine poly(ionic liquid)s (215 mg g−1). Meanwhile, it exhibits fast sorption kinetics (92% in 2 min), good β and γ radiation-resistance, excellent regeneration and eminent removal efficiency in high alkaline conditions (83%). These superior traits endow that P[C4(VIM)2]Cl2@MIL-101 effectively separated TcO4- from simulated Hanford Low-activity Waste (LAW) Melter off-gas scrubber solution tested in this work. DFT density functional theory confirms that the strong electrostatic attraction and minimum Gibbs free energy (−6.2 kcal mol−1) achieve high selective adsorption for TcO4-. P[C4(VIM)2]Cl2@MIL-101 demonstrates the considerable potential to remove TcO4- from radioactive contaminants. more...
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- 2022
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14. Highly efficient and selective capture of TcO4− or ReO4− by imidazolium-based ionic liquid polymers
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Zhenning Lou, Ying Xiong, Wenyan Zhao, Yuejiao Wang, Weijun Shan, Mengnan Huang, and Kan Lixin
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chemistry.chemical_classification ,General Chemical Engineering ,Inorganic chemistry ,chemistry.chemical_element ,02 engineering and technology ,General Chemistry ,Polymer ,Rhenium ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Alkali metal ,01 natural sciences ,Industrial and Manufacturing Engineering ,0104 chemical sciences ,chemistry.chemical_compound ,Adsorption ,chemistry ,Molybdenum ,Selective adsorption ,Ionic liquid ,Environmental Chemistry ,0210 nano-technology ,Selectivity - Abstract
99Technetium (99Tc) is one of the most dangerous radioactive isotopes in the legacy nuclear waste, and harmful to the environment and human health. Effectively removing it remains a long-term challenge. Herein a resin-like imidazolium-based ionic liquid polymer (DVB-2C8VEIMBr) was prepared for selective adsorption of TcO4− (ReO4− as an alternative for laboratory operation). It is manifested that DVB-2C8VEIMBr integrates high adsorption capacity (313.28 mg·g−1) and selectivity (90.68% in 6000 times excess of SO42− ions). A real-scenario experiment exhibits DVB-2C8VEIMBr can remove up to 93% of TcO4− from the simulated Hanford LAW scrubber solution. More importantly, DVB-2C8VEIMBr displays super acid and alkaline resistance and stability after immersing for 8 months under extreme conditions of 3 M HCl and 2 M NaOH. It can also effectively separate rhenium from molybdenum solution in the range of 3 M HCl - pH 2. Additionally, it still showed perfect regeneration performance after 10 cycles. In particular, this work demonstrates the feasibility of imidazolium-based ionic liquid adsorbents in the TcO4− or ReO4− immobilization process, which can be applied to capture these radioactive oxygen anions under high acid and high alkali conditions. more...
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- 2021
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15. Identification of coronary heart disease biomarkers with different severities of coronary stenosis in human urine using non-targeted metabolomics based on UPLC-Q-TOF/MS
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Chunquan Yu, Mengnan Huang, Zhu Li, Yubo Li, Huan Zhao, Xuemeng Cai, Shan Gao, Yuechen Liu, Lin Li, Yijia Liu, and Tianpu Zhang
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0301 basic medicine ,Adult ,Male ,medicine.medical_specialty ,Time Factors ,Clinical Biochemistry ,Coronary Disease ,Coronary stenosis ,Urine ,Biochemistry ,Severity of Illness Index ,Mass Spectrometry ,Pathogenesis ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Metabolomics ,Internal medicine ,medicine ,Humans ,Chromatography, High Pressure Liquid ,Cause of death ,Aged ,Aged, 80 and over ,Fatty acid metabolism ,business.industry ,Biochemistry (medical) ,Coronary Stenosis ,General Medicine ,Middle Aged ,medicine.disease ,Coronary heart disease ,Stenosis ,030104 developmental biology ,chemistry ,030220 oncology & carcinogenesis ,Cardiology ,Female ,business ,Biomarkers - Abstract
Background Coronary heart disease (CHD) is the leading cause of death worldwide, and its pathogenesis has attracted much attention. Metabolomics serves as an important tool for diagnosing diseases and exploring their pathogenesis in recent years. In this study, CHD patients were studied by comparing them with normal subjects to elucidate biomarkers that are linearly correlated with the severity of coronary stenosis. Methods An ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was used to analyze the urine metabolites of CHD patients and normal subjects. A total of 131 subjects included 27 patients who presented with 50–69% coronary stenosis, 22 with 70–89% stenosis, 29 with 90–99% stenosis, 24 with 100% stenosis, and 29 normal subjects. Results A total of 14 potential biomarkers associated with CHD were identified, and among them 4 biomarkers were linearly correlated with the severity of coronary stenosis in CHD patients. The metabolic pathways involved were amino acid metabolism, fatty acid metabolism, energy metabolism, and other pathways. Conclusion This study identified the biomarkers and metabolic pathways that may be involved in the occurrence and development of CHD, laying a theoretical foundation for better diagnosis and treatment of CHD in the future. more...
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- 2019
16. Effect of hypercholesterolemia alone or combined with hypertension on the degree of coronary artery stenosis in patients with coronary heart disease angina pectoris
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Xiaoxue Xue, Mengnan Huang, Yilan Xu, Shuming Gao, Mingjie Yang, Yijia Liu, Shan Gao, Lin Li, Shuo Wang, and Chunquan Yu
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medicine.medical_specialty ,retrospective study ,Hypercholesterolemia ,Gensini score ,Coronary stenosis ,Angina Pectoris ,Angina ,03 medical and health sciences ,0302 clinical medicine ,Study Protocol Clinical Trial ,Internal medicine ,medicine ,Humans ,Multicenter Studies as Topic ,cardiovascular diseases ,030212 general & internal medicine ,Retrospective Studies ,Cause of death ,business.industry ,coronary heart disease angina pectoris ,Medical record ,Clinical Studies as Topic ,Coronary Stenosis ,Retrospective cohort study ,General Medicine ,medicine.disease ,Coronary heart disease ,Coronary arteries ,Clinical research ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Hypertension ,Cardiology ,business ,Research Article - Abstract
Background: Coronary heart disease (CHD) is the leading cause of death globally. Angina pectoris is closely associated with coronary artery insufficiency, which seriously affects the quality of life and work of patients. Hypercholesterolemia and hypertension (HTN) are risk factors for CHD angina pectoris. The correlation between hypercholesterolemia with or without HTN and the severity of coronary arteries has not been clarified. Objective: To explore the correlation between hypercholesterolemia and the degree of coronary artery stenosis (CAS) of CHD angina pectoris, and to further research the influence of HTN on total cholesterol level and CAS, so as to provide guidance for clinical prevention and treatment. Methods: A multicenter, retrospective clinical study was conducted in the medical records management system of 6 hospitals in Tianjin. Patients who were suffered from CHD angina pectoris and aged from 35 to 75 years old are involved. They hospitalized in the Department of Cardiology between September 1, 2014, and September 1, 2019, and underwent coronary angiography. We divide patients into 3 groups based on the total cholesterol level, the degree of CAS is evaluated by Gensini score, and further divide them into 6 subgroups based on with or without HTN. Collect and analyze the demographics, laboratory information, clinical outcome data, and coronary angiographic data of patients. Conclusion: Through clinical research data, the study will help to provide guidance for the prevention and treatment of CHD angina pectoris complicated with diseases and promote further research. more...
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- 2020
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17. Copolymers of vinylimidazolium-based ionic liquids and divinylbenzene for adsorption of TcO4− or ReO4−
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Shuyao Wu, Peng Zhou, Ying Xiong, Shanshan Xing, Mengnan Huang, Weijun Shan, Zhenning Lou, and Cui Junshuo
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Perrhenate ,Elution ,Inorganic chemistry ,0211 other engineering and technologies ,Metals and Alloys ,chemistry.chemical_element ,02 engineering and technology ,Rhenium ,Divinylbenzene ,Industrial and Manufacturing Engineering ,chemistry.chemical_compound ,Adsorption ,020401 chemical engineering ,chemistry ,Molybdenum ,Ionic liquid ,Materials Chemistry ,Copolymer ,0204 chemical engineering ,021102 mining & metallurgy - Abstract
Technetium (99Tc), a radionuclide generated from uranium fission in nuclear reactors, has posed a major threat to humans due to its long half-life and radioactivity. Therefore, it is urgent to develop a strategy of selectively and efficiently capturing of 99Tc. In this work, a series of solid copolymers (denoted as DVB-[CxClVim][Cl]) were synthesized for efficient adsorption of perrhenate (ReO4−, a surrogate for TcO4−) from mixed ions solution. The adsorbents with vinylimidazolium-based ionic liquid as functional group and divinylbenzene (DVB) as the basic framework exhibited stable structure and good ReO4−adsorption performance. The influences of the linear n-alkyl chain length on the morphology and adsorption property of the copolymers were discussed in detail. The maximum uptake of Re(VII) on DVB-[C4ClVim][Cl] was 517.61 mg·g−1. Rhenium could be separated from molybdenum in the presence of co-anions and co-cations by DVB-[C6ClVim][Cl], which demonstrated its good adsorption selectivity. The kinetic studies showed that pseudo-second-order model was more suitable for describing the behavior of Re(VII) adsorption. The adsorption mechanism was ion-exchange between Cl− and ReO4− confirmed by FI-IR, IC and XPS analysis. Additionally, DVB-[CxClVim][Cl] remained effective Re(VII) capture ability after eight adsorption/elution cycles, demonstrating their good reusability. more...
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- 2019
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18. Adjuvant treatment of coronary heart disease angina pectoris with Chinese patent medicine
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Jing Xie, Kaijun Niu, Mengnan Huang, Xianliang Wang, Qiang Xu, Ziyi Jiao, Yilan Xu, Yanqi Song, Shuming Gao, Xiaoxue Xue, Yijia Liu, Shan Gao, Chunquan Yu, Sheng Gao, Zhu Li, Dandan Shen, Lin Li, and Chunjie Li more...
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Male ,medicine.medical_specialty ,Chinese patent medicine ,medicine.medical_treatment ,Traditional Chinese medicine ,Sudden death ,Angina Pectoris ,Angina ,03 medical and health sciences ,0302 clinical medicine ,Study Protocol Clinical Trial ,Internal medicine ,medicine ,Humans ,Prospective Studies ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Medicine, Chinese Traditional ,Prospective cohort study ,Adverse effect ,business.industry ,coronary heart disease angina pectoris ,General Medicine ,Middle Aged ,medicine.disease ,Treatment Outcome ,prospective clinical study ,Research Design ,030220 oncology & carcinogenesis ,Practice Guidelines as Topic ,Female ,business ,Adjuvant ,Drugs, Chinese Herbal ,Research Article - Abstract
Background: Patients with coronary heart disease (CHD) angina pectoris are in critical condition, which can cause sudden death, myocardial infarction, and other adverse events, and bring serious burden to families and society. Timely treatment should be given to improve the condition. Western medicine treatment of angina pectoris failed to meet the demand of angina symptom control. Objective: It is hoped that the research method with higher evidential value will be adopted to compare the short-term, medium-term, and long-term effects of Chinese patent medicine combined with conventional western medicine and conventional western medicine alone in the treatment of CHD angina pectoris, so as to tap the clinical efficacy advantages of traditional Chinese medicine (TCM) and provide reliable data support for its clinical application. Methods: A prospective cohort study was conducted among patients with CHD angina pectoris who were treated with oral Chinese patent medicine and conventional western medicine. The patients were divided into exposed group and nonexposed group according to whether or not the patients with CHD angina pectoris were treated with Chinese patent medicine. The exposed group was treated with TCM combined with conventional western medicine, while the nonexposed group was treated with conventional western medicine alone. Patients need to be hospitalized for 2 weeks as the introduction period and whether to enter the group is determined according to the treatment and medication conditions of the patients. The follow-up time points were 0th, 4th, 12th, 24th, and 48th weeks. The main events and secondary events were used as the evaluation criteria for clinical efficacy of CHD angina pectoris. In the experimental study, we will use strict indicators to detect standard operation procedure for multinomics and bacterial flora detection. Conclusion: This study will provide evidence for the clinical efficacy advantages of Chinese patent medicine and reliable support for its clinical application through test data. more...
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- 2019
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19. SHALLOW GROUNDWATER UTILIZATION ROLE OF WHEAT BASED ON DIFFERENT SOIL AND DIFFERENT GROUNDWATER DEPTH.
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Mei Zhu, Ahmed, Bazai Nazir, Xueling Li, Mengnan Huang, Muhammad, Tahir, and Lei Ming
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In order to make full use of Shallow groundwater, reduce the amount of water used for irrigation, and improve the efficiency of agricultural water resources utilization in the water shortage area of Huaibei Plain, this paper carried out experiments on wheat groundwater use based on different soils and different groundwater depths. The typical shajiang black soil and yellow fluvo-aquic soil in Huaibei Plain were selected for the experiments. The groundwater control depth was 10 levels within the range of 0-4 m, and the experiment was carried out to measure the evapotranspiration of the crops. The variation of phreatic water evaporation with soil depth and groundwater depth at six different growth stages was summarized. The results showed that the phreatic water evaporation of wheat decreased with the increase in groundwater depth. Under the same burial depth, the evapotranspiration of yellow fluvo-aquic soil was greater than that of shajiang black soil. The above results showed that the groundwater use efficiency was the highest in the case of yellow fluvo-aquic soil and 1.0 m of groundwater depth. [ABSTRACT FROM AUTHOR] more...
- Published
- 2018
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