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1. Surgical site infections after kidney transplantation are independently associated with graft loss

Author

Amico, Patrizia, Aubert, John-David, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Cairoli, Anne, Chalandon, Yves, De Geest, Sabina, De Rougemont, Olivier, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Golshayan, Déla, Goossens, Nicolas, Haidar, Fadi, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Mueller, Nicolas J., Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Pazeller, Rosemarie, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schaub, Stefan, Scherrer, Alexandra, Schnyder, Aurelia, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Simonetta, Federico, Stampf, Susanne, Steiger, Jürg, Stirnimann, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhelm, Markus, Yerly, Patrick, Schreiber, Peter W., Hoessly, Linard D., Boggian, Katia, Neofytos, Dionysios, van Delden, Christian, Egli, Adrian, Hirzel, Cédric, Schmied, Bruno, Guerke, Lorenz, Matter, Maurice, de Rougemont, Olivier, Bonani, Marco, Sidler, Daniel, and Kuster, Stefan P.

Published
2024
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2. BK polyomavirus serotype-specific antibody responses in blood donors and kidney transplant recipients with and without new-onset BK polyomavirus-DNAemia: A Swiss Transplant Cohort Study

Author

Amico, Patrizia, Bachofner, Adrian, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Françoise-Isabelle, Bochud, Pierre-Yves, Borner, Petra, Branca, Sanda, Cairoli, Anne, Catana, Emmanuelle, Chalandon, Yves, Compagnon, Philippe, De Geest, Sabina, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Flammer, Andreas, Frossard, Jaromil, Golshayan, Dela, Goossens, Nicolas, Haidar, Fadi, Halter, Jürg, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Khanna, Nina, Koller, Michael, Kremer, Andreas, Krueger, Thorsten, Kuhn, Christian, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, L'Huillier, Arnaud, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Müller, Nicolas, Müller, Jelena, Müller-Arndt, Ulrike, Nägeli, Mirjam, Neofytos, Dionysios, Nilsson, Jakob, Pascual, Manuel, Pazeller, Rosmarie, Reineke, David, Rick, Juliane, Rössler, Fabian, Rothlin, Silvia, Schachtner, Thomas, Schaub, Stefan, Schneidawind, Dominik, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Sidler, Daniel, Simonetta, Federico, Steiger, Jürg, Stirnimann, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wehmeier, Caroline, Wilhelm, Markus, Yerly, Patrick, Hillenbrand, Caroline A., Bani, Dorssa Akbari, Follonier, Océane, Kaur, Amandeep, Weissbach, Fabian H., Wernli, Marion, Wilhelm, Maud, Leuzinger, Karoline, Binet, Isabelle, Hirzel, Cédric, and Mueller, Nicolas J.

Published
2024
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3. Reintegration Into the Workforce After Kidney Transplantation Based on Urbanization Status in Switzerland

Author

Amico, Patrizia, Bachofner, Adrian, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Cairoli, Anne, Catana, Emmanuelle, Chalandon, Yves, De Geest, Sabina, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Frossard, Jaromil, Garzoni, Christian, Golshayan, Déla, Goossens, Nicolas, Haidar, Fadi, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans, Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Kremer, Andreas, Krueger, Thorsten, Kuhn, Christian, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Müller, Nicolas, Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Pazeller, Rosemarie, Posfay-Barbe, Klara, Reineke, David, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rössler, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schaub, Stefan, Scherrer, Alexandra, Schneidawind, Dominik, Schnyder, Aurelia, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Simonetta, Federico, Steiger, Jürg, Stirniman, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhlem, Markus, Yerly, Patrick, Bocchi, Federica, Müller, Selina, Binet, Isabelle, Golshayan, Dela, Müller, Thomas, Sidler, Daniel, and Storni, Federico

Published
2024
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4. Outcome of Patients Transplanted for C3 Glomerulopathy and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis

Author

Amico, Patrizia, Aubert, John-David, Banz, Vanessa, Beckmann, Sonia, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Chalandon, Yves, De Geest, Sabina, De Seigneux Michael Dickenmann, Sophie, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Gaudet, Christophe, Golshayan, Déla, Goossens, Nicolas, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laager, Mirjam, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Mercay, Aurelia, Mettler, Karin, Mueller, Nicolas J., Müller, Antonia, Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schanz, Urs, Schaub, Stefan, Schwab, Simon, Schnyder, Aurelia, Schuurmans, Macé, Sengstag, Thierry, Simonetta, Federico, Steiger, Jürg, Stirniman, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhlem, Markus, Yerly, Patrick, Halfon, Matthieu, Taffé, Patrick, Bucher, Christian, Haidar, Fadi, Huynh-do, Uyen, Mani, Laila-Yasmin, Wehmeier, Caroline, Fakhouri, Fadi, and Golshayan, Dela

Published
2024
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5. The MELD upgrade exception: a successful strategy to optimize access to liver transplantation for patients with high waiting list mortality

Author

Amico, Patrizia, Axel, Andres, Aubert, John-David, Banz, Vanessa, Sonja, Beckmann, Beldi, Guido, Benden, Christian, Berger, Christoph, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Carrel, Thierry, Catana, Emmanuelle, Chalandon, Yves, de Geest, Sabina, de Rougemont, Olivier, Dickenmann, Michael, Dreifuss, Joëlle L., Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Soccal, Paola G., Gaudet, Christophe, Giostra, Emiliano, Golshayan, Déla, Hadaya, Karine, Halter, Jörg, Hauri, Dimitri, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans, Hirt, Patricia, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laesser, Bettina, Lang, Brian, Lehmann, Roger, Leichtle, Alexander, Lovis, Christian, Manuel, Oriol, Marti, Hans-Peter, Martin, Pierre Y., Martinelli, Michele, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Meylan, Pascal, Mueller, Nicolas, Müller, Antonia, Müller, Thomas, Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Pascual, Manuel, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schanz, Urs, Schaub, Stefan, Schnyder, Aurelia, Schuurmans, Macé, Simonetta, Federico, Staufer, Katharina, Stampf, Susanne, Steiger, Jürg, Stirniman, Guido, Stürzinger, Ueli, Toso, Christian, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhlem, Markus, Yerly, Patrick, Dirchwolf, Melisa, Becchetti, Chiara, Gschwend, Sarah G., Dutkowski, Philipp, Beyeler, Franziska, Schropp, Jonas, and Dufour, Jean-François

Published
2022
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6. The MELD upgrade exception: a successful strategy to optimize access to liver transplantation for patients with high waiting list mortality

Author

Dirchwolf, Melisa, primary, Becchetti, Chiara, additional, Gschwend, Sarah G., additional, Toso, Christian, additional, Dutkowski, Philipp, additional, Immer, Franz, additional, Beyeler, Franziska, additional, Rossi, Simona, additional, Schropp, Jonas, additional, Dufour, Jean-François, additional, Banz, Vanessa, additional, Amico, Patrizia, additional, Axel, Andres, additional, Aubert, John-David, additional, Sonja, Beckmann, additional, Beldi, Guido, additional, Benden, Christian, additional, Berger, Christoph, additional, Binet, Isabelle, additional, Bochud, Pierre-Yves, additional, Branca, Sanda, additional, Bucher, Heiner, additional, Carrel, Thierry, additional, Catana, Emmanuelle, additional, Chalandon, Yves, additional, de Geest, Sabina, additional, de Rougemont, Olivier, additional, Dickenmann, Michael, additional, Dreifuss, Joëlle L., additional, Duchosal, Michel, additional, Fehr, Thomas, additional, Ferrari-Lacraz, Sylvie, additional, Garzoni, Christian, additional, Soccal, Paola G., additional, Gaudet, Christophe, additional, Giostra, Emiliano, additional, Golshayan, Déla, additional, Hadaya, Karine, additional, Halter, Jörg, additional, Hauri, Dimitri, additional, Heim, Dominik, additional, Hess, Christoph, additional, Hillinger, Sven, additional, Hirsch, Hans, additional, Hirt, Patricia, additional, Hofbauer, Günther, additional, Huynh-Do, Uyen, additional, Koller, Michael, additional, Laesser, Bettina, additional, Lang, Brian, additional, Lehmann, Roger, additional, Leichtle, Alexander, additional, Lovis, Christian, additional, Manuel, Oriol, additional, Marti, Hans-Peter, additional, Martin, Pierre Y., additional, Martinelli, Michele, additional, Mellac, Katell, additional, Merçay, Aurélia, additional, Mettler, Karin, additional, Meylan, Pascal, additional, Mueller, Nicolas, additional, Müller, Antonia, additional, Müller, Thomas, additional, Müller-Arndt, Ulrike, additional, Müllhaupt, Beat, additional, Nägeli, Mirjam, additional, Pascual, Manuel, additional, Posfay-Barbe, Klara, additional, Rick, Juliane, additional, Rosselet, Anne, additional, Rothlin, Silvia, additional, Ruschitzka, Frank, additional, Schanz, Urs, additional, Schaub, Stefan, additional, Schnyder, Aurelia, additional, Schuurmans, Macé, additional, Simonetta, Federico, additional, Staufer, Katharina, additional, Stampf, Susanne, additional, Steiger, Jürg, additional, Stirniman, Guido, additional, Stürzinger, Ueli, additional, Van Delden, Christian, additional, Venetz, Jean-Pierre, additional, Villard, Jean, additional, Vionnet, Julien, additional, Wick, Madeleine, additional, Wilhlem, Markus, additional, and Yerly, Patrick, additional

Published
2022
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7. Use of induction therapy in pediatric heart transplant recipients in Switzerland – Analysis of the Swiss national database

Author

Schweiger, M., primary, Erdil, T., additional, Di Bernardo, S., additional, Balmer, C., additional, Yildiz, M., additional, Kadner, A., additional, Amico, Patrizia, additional, Axel, Andres, additional, Aubert, John-David, additional, Banz, Vanessa, additional, Sonja, Beckmann, additional, Beldi, Guido, additional, Berger, Christoph, additional, Berishvili, Ekaterine, additional, Binet, Isabelle, additional, Bochud, Pierre-Yves, additional, Branca, Sanda, additional, Bucher, Heiner, additional, Carrel, Thierry, additional, Catana, Emmanuelle, additional, Chalandon, Yves, additional, De Geest, Sabina, additional, De Rougemont, Olivier, additional, Dickenmann, Michael, additional, Dreifuss, Joëlle Lynn, additional, Duchosal, Michel, additional, Fehr, Thomas, additional, Ferrari-Lacraz, Sylvie, additional, Garzoni, Christian, additional, Soccal, Paola Gasche, additional, Gaudet, Christophe, additional, Golshayan, Déla, additional, Goossens, Nicolas, additional, Hadaya, Karine, additional, Halter, Jörg, additional, Heim, Dominik, additional, Hess, Christoph, additional, Hillinger, Sven, additional, Hirsch, Hans, additional, Hirt, Patricia, additional, Hofbauer, Günther, additional, Huynh-Do, Uyen, additional, Immer, Franz, additional, Koller, Michael, additional, Laager, Mirjam, additional, Laesser, Bettina, additional, Lehmann, Roger, additional, Leichtle, Alexander, additional, Lovis, Christian, additional, Manuel, Oriol, additional, Marti, Hans-Peter, additional, Martin, Pierre Yves, additional, Martinelli, Michele, additional, McLin, Valérie, additional, Mellac, Katell, additional, Merçay, Aurélia, additional, Mettler, Karin, additional, Mueller, Nicolas, additional, Müller, Antonia, additional, Müller, Thomas, additional, Müller-Arndt, Ulrike, additional, Müllhaupt, Beat, additional, Nägeli, Mirjam, additional, Oldani, Graziano, additional, Pascual, Manuel, additional, Posfay-Barbe, Klara, additional, Rick, Juliane, additional, Rosselet, Anne, additional, Rossi, Simona, additional, Rothlin, Silvia, additional, Ruschitzka, Frank, additional, Schanz, Urs, additional, Schaub, Stefan, additional, Schnyder, Aurelia, additional, Schuurmans, Macé, additional, Sengstag, Thierry, additional, Simonetta, Federico, additional, Staufer, Katharina, additional, Stampf, Susanne, additional, Steiger, Jürg, additional, Stirniman, Guido, additional, Stürzinger, Ueli, additional, Van Delden, Christian, additional, Venetz, Jean-Pierre, additional, Villard, Jean, additional, Vionnet, Julien, additional, Wick, Madeleine, additional, Wilhlem, Markus, additional, and Yerly, Patrick, additional

Published
2021
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8. Epidemiology and outcomes of bone and joint infections in solid organ transplant recipients

Author

Pham, Truong‐Thanh, Andrey, Diego O., Stampf, Susanne, Burkhard, Sara H., Hirzel, Cédric, Tschopp, Johnathan, Ullrich, Kathrin, Strahm, Carol, Schreiber, Peter W., Boillat‐Blanco, Noémie, Garzoni, Christian, Khanna, Nina, Manuel, Oriol, Mueller, Nicolas J., Suva, Domizio, Delden, Christian, Uçkay, Ilker, Neofytos, Dionysios, Amico, Patrizia, Axel, Andres, Aubert, John‐David, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Isabelle, Bochud, Pierre‐Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Cairoli, Anne, Chalandon, Yves, De Geest, Sabina, De Rougemont, Olivier, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari‐Lacraz, Sylvie, Golshayan, Déla, Goossens, Nicolas, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hofbauer, Günther, Huynh‐Do, Uyen, Immer, Franz, Koller, Michael, Laager, Mirjam, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Marti, Hans‐Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Müller, Antonia, Müller‐Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Pazeller, Rosemarie, Posfay‐Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schanz, Urs, Schaub, Stefan, Scherrer, Alexandra, Schnyder, Aurelia, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Simonetta, Federico, Steiger, Jürg, Stirnimann, Guido, Stürzinger, Ueli, Venetz, Jean‐Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhelm, Markus, and Yerly, Patrick

Abstract

Bone and joint infection (BJI) epidemiology and outcomes in solid organ transplant recipients (SOTr) remain largely unknown. We aim to describe BJI in a multi‐center cohort of SOTr (Swiss Transplant Cohort Study). All consecutive SOTr with BJI (01.05.2008–31.12.2019) were included. A nested case–control study to identify risk factors for BJI was performed. Among 4482 patients, 61 SOTr with 82 BJI were included, at an incidence of 1.4% (95% CI 1.1–1.7), higher in heart and kidney‐pancreas SOTr (Gray's test p< .01). Although BJI were predominately late events (median of 18.5 months post‐SOT), most infections occurred during the first year post‐transplant in thoracic SOTr. Diabetic foot osteomyelitis was the most frequent infection (38/82, 46.3%), followed by non‐vertebral osteomyelitis (26/82, 31.7%). Pathogens included Gram‐positive cocci (70/131, 53.4%), Gram‐negative bacilli (34/131, 26.0%), and fungi (9/131, 6.9%). BJI predictors included male gender (OR 2.94, 95% CI 1.26–6.89) and diabetes (OR 2.97, 95% CI 1.34–6.56). Treatment failure was observed in 25.9% (21/81) patients and 1‐year mortality post‐BJI diagnosis was 14.8% (9/61). BJI remain a rare event in SOTr, associated with subtle clinical presentations, high morbidity and relapses, requiring additional studies in the future. In solid organ transplant recipients, bone and joint infections, rare complications with subtle clinical presentation, high morbidity and frequent relapse, require special attention from treating physicians.

Published
2022
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9. Pre‐transplant Social Adaptability Index and clinical outcomes in renal transplantation: The Swiss Transplant Cohort study.

Author

Denhaerynck, Kris, Goldfarb‐Rumyantzev, Alexander S., Sandhu, Gurprataap, Beckmann, Sonja, Huynh‐Do, Uyen, Binet, Isabelle, De Geest, Sabina, Brack, Gaëlle, Büttiker, Anita, Künzler, Petra, Leppla, Lynn, Ribaut, Janette, Boehler, Annette, Koller, Michael, Beerli, Nadine, Mauthner, Oliver, Berben, Lut, Merçay, Aurélia, Hadaya, Karine, and Seiler, Annina

Subjects
TREATMENT effectiveness, COHORT analysis, SOCIAL sciences education, SUBSTANCE abuse, KIDNEY transplantation
Abstract

Background: The impact of pre‐transplant social determinants of health on post‐transplant outcomes remains understudied. In the United States, poor clinical outcomes are associated with underprivileged status, as assessed by the Social Adaptability Index (SAI), a composite score of education, employment status, marital status, household income, and substance abuse. Using data from the Swiss Transplant Cohort Study (STCS), we determined the SAI's predictive value regarding two post‐transplant outcomes: all‐cause mortality and return to dialysis. Methods: Between 2012 and 2018, we included adult renal transplant patients (aged ≥ 18 years) with pre‐transplant assessment SAI scores, calculated from a STCS Psychosocial Questionnaire. Time to all‐cause mortality and return to dialysis were predicted using Cox regression. Results: Of 1238 included patients (mean age: 53.8 ± 13.2 years; 37.9% female; median follow‐up time: 4.4 years [IQR: 2.7]), 93 (7.5%) died and 57 (4.6%) returned to dialysis. The SAI's hazard ratio was 0.94 (95%CI: 0.88–1.01; p =.09) for mortality and 0.93 (95%CI: 0.85–1.02; p =.15) for return to dialysis. Conclusions: In contrast to most published studies on social deprivation, analysis of this Swiss sample detected no significant association between SAI score and mortality or return to dialysis. [ABSTRACT FROM AUTHOR]

Published
2021
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11. Surgical site infections after kidney transplantation are independently associated with graft loss

Author

Schreiber, Peter W., Hoessly, Linard D., Boggian, Katia, Neofytos, Dionysios, van Delden, Christian, Egli, Adrian, Dickenmann, Michael, Hirzel, Cédric, Manuel, Oriol, Koller, Michael, Rossi, Simona, Banz, Vanessa, Schmied, Bruno, Guerke, Lorenz, Matter, Maurice, de Rougemont, Olivier, Bonani, Marco, Golshayan, Déla, Schnyder, Aurelia, Sidler, Daniel, Haidar, Fadi, Kuster, Stefan P., Stampf, Susanne, Mueller, Nicolas J., Amico, Patrizia, Aubert, John-David, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Cairoli, Anne, Chalandon, Yves, De Geest, Sabina, De Rougemont, Olivier, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Golshayan, Déla, Goossens, Nicolas, Haidar, Fadi, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Mueller, Nicolas J., Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Pazeller, Rosemarie, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schaub, Stefan, Scherrer, Alexandra, Schnyder, Aurelia, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Simonetta, Federico, Stampf, Susanne, Steiger, Jürg, Stirnimann, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhelm, Markus, and Yerly, Patrick

Abstract

Surgical site infections (SSI) are common healthcare-associated infections. SSIs after kidney transplantation (K-Tx) can endanger patient and allograft survival. Multicenter studies on this early post-transplant complication are scarce. We analyzed consecutive adult K-Tx recipients enrolled in the Swiss Transplant Cohort Study (STCS) that received a K-tx between May 2008 and September 2020. All data were prospectively collected with the exception of the categorization of SSI that was performed retrospectively according to the Centers for Disease Control and Prevention criteria. A total of 58 out of 3059 (1.9%) K-Tx recipients were affected by SSIs. Deep incisional (15, 25.9%) and organ/space infections (34, 58.6%) predominated. In the majority of SSIs (52, 89.6%) bacteria were detected, most frequently Escherichia coli(15, 28.9%), Enterococcusspp. (14, 26.9%), and coagulase-negative staphylococci (13, 25.0%). A BMI ≥25kg/m2(multivariable OR 2.16, 95% CI 1.07-4.34, P=0.023) and delayed graft function (multivariable OR 2.88, 95% CI 1.56-5.34, P=0.001) were independent risk factors for SSI. In Cox proportional hazard models, SSI was independently associated with graft loss (multivariable HR 3.75, 95% CI 1.35-10.38, P=0.011). In conclusion, SSI was a rare complication after K-Tx. BMI ≥25kg/m2and delayed graft function were independent risk factors. SSI were independently associated with graft loss.

Published
2023
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