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1. List of contributors

Author

Aizawa, Shin-Ichi, primary, Alberdi, Pilar, additional, Alexander, David C., additional, Alía, Alberto, additional, Allison, D.G., additional, Amyes, Sebastian G.B., additional, An, Haoran, additional, Andrade, María J., additional, Antelmann, Haike, additional, Arias, Cesar A., additional, Asensio, Miguel A., additional, Axell-House, Dierdre B., additional, Bae, Hee-Won, additional, Baena, Laura Muñoz, additional, Baig, Abdul Mannan, additional, Bailey, Spenser O., additional, Baize, Sylvain, additional, Baldi, Pablo C., additional, Barbosa, Angela Silva, additional, Barbuddhe, Sukhadeo B., additional, Bard, Emilie, additional, Barry, Eileen M., additional, Basarab, Gregory S., additional, Beloborodova, N.V, additional, Bermúdez, Elena, additional, Bidmos, Fadil A., additional, Bisgaard, Magne, additional, Blakely, Garry W., additional, Bloch, Evan, additional, Boesen, Thias Oberg, additional, Bose, Dipayan, additional, Botero, Javier Enrique, additional, Bouabe, Hicham, additional, Bouchard, Michael J., additional, Bozue, Joel A., additional, Bradbury, Richard S., additional, Brett Moreau, G., additional, Cabezas-Cruz, Alejandro, additional, Cai, Rong-Jun, additional, Calderón, Enrique J., additional, Cao, Boyang, additional, Carmena, David, additional, Carvalho, Eneas, additional, Caulfield, Amanda D., additional, Cen, Shan, additional, Chai, Jong-Yil, additional, Chamberland, Robin R., additional, Champredon, David, additional, Chan, Edward D., additional, Charbon, Godefroid, additional, Chato, Connor, additional, Chelomina, G.N., additional, Chen, Jingyu, additional, Chen, Min, additional, Chen, Shuyu, additional, Chen, Suilin, additional, Chen, Yanfei, additional, Chen, Zhaoyuan, additional, Cheng, Aimin, additional, Cheng, Keding, additional, Chiu, Charles Y., additional, Cho, You-Hee, additional, Christensen, Henrik, additional, Chrtdernevskaya, E.A., additional, Contreras, Adolfo, additional, Contreras, Marinela, additional, Córdoba, Juan J., additional, Córdoba, María G., additional, Costa, Rita, additional, Cote, Christopher K., additional, Cui, Xiangling, additional, Cui, Yujun, additional, Dacal, Elena, additional, Dammann, Allison N., additional, Das, Shubhagata, additional, Dashti, Alejandro, additional, de la Fuente, José, additional, de la Garza, Mireya, additional, Delgado, Josué, additional, Delgado-Cuesta, Juan, additional, Deng, Haiteng, additional, Deng, Li, additional, Dey, Debajit, additional, Dhama, Kuldeep, additional, Diego, Juan García-Bernalt, additional, Ding, Hao, additional, Doern, Christopher D., additional, Dorman, Charles J., additional, Du, Zongmin, additional, Dunbar, Sherry A., additional, Duthie, Malcolm, additional, Dybvig, Kevin F., additional, Eakin, Ann E., additional, Eallonardo, Samuel J., additional, Eberly, Allison R., additional, Echeverry, Adriana Jaramillo, additional, Egland, Paul G., additional, El Zowalaty, Mohamed E., additional, Endsley, Janice Jones, additional, Eom, Keeseon S., additional, Evans, Benjamin A., additional, Falkinham, Joseph O., additional, Feng, Siwei, additional, Feng, Yaoyu, additional, Feng, Zongdi, additional, Fernández-Soto, Pedro, additional, Ferreira, Roux-Cil, additional, Flores-Huerta, Nadia, additional, Foster, Timothy J., additional, Fox-Moon, Sandra M., additional, Fraga, Tatiana Rodrigues, additional, Fredricks, David N., additional, Freitag, Nancy E., additional, Frimodt-Møller, Jakob, additional, Fuller, Risa, additional, Ganesh, Balasubramanian, additional, Gao, Ning, additional, García-Carnero, Laura C., additional, Garzetti, Debora, additional, Geoghegan, Joan A., additional, Ghenim, Raed, additional, Giambartolomei, Guillermo H., additional, Gilbert, Nicole M., additional, Gillis, Thomas Phillip, additional, Gladstone, Camilla A., additional, Gómez-Gaviria, Manuela, additional, Gómez-Marín, Jorge E., additional, Gong, Tengfang, additional, González, Ramón A., additional, Gray-Owen, Scott D., additional, Gu, Bing, additional, Guzmán-Téllez, Paula, additional, Hajal, Caroline, additional, Han, Yanping, additional, Hao, Yi, additional, Harrington, Amanda T., additional, Harris, Jason B., additional, Harvill, Eric T., additional, Hasan, S. Saif, additional, He, Guang-Jun, additional, He, Yongqun, additional, Heffron, Jared D., additional, Hidalgo, Paloma, additional, Hindiyeh, Musa Y., additional, Hreha, Teri N., additional, Hu, Xiaoyu, additional, Huang, Guanghua, additional, Huang, Jiangqing, additional, Huang, Liang, additional, Huang, Shifeng, additional, Huang, Xingxu, additional, Huang, Xueting, additional, Huang, Yilun, additional, Huffman, Anthony, additional, Humphreys, Tricia L., additional, Hunstad, David A., additional, Inglis, Timothy J.J., additional, Isaac, Lourdes, additional, Jacobs, Samantha E., additional, Janowicz, Diane M., additional, Jeon, Hyeong-Kyu, additional, Ji, Quanjiang, additional, Jia, Qi, additional, Jia, Wei, additional, Jin, Shouguang, additional, Jneidi, Lama, additional, Jose, Shinsmon, additional, Jung, Bong-Kwang, additional, Kattan, Randa, additional, Kaushik, Rahul, additional, Khare, Reeti, additional, Kim, Eun Sook, additional, Kirn, Thomas J., additional, Koo, Hyun, additional, Köster, Pamela C., additional, Krause, Peter J., additional, Kumar, Sanjai, additional, Kupz, Andreas, additional, Lambert, P.A., additional, Lamont, Richard J., additional, Langford, Paul R., additional, Lebeaux, David, additional, Legname, Giuseppe, additional, Li, Bin, additional, Li, Chunhao, additional, Li, Fen, additional, Li, Jun, additional, Li, Lanjuan, additional, Li, Ruofan, additional, Li, Ruoyu, additional, Li, Ting, additional, Li, Yang-Yang, additional, Li, Yanhua, additional, Li, Zhuorong, additional, Liang, Xiaomeng, additional, Liao, Guojian, additional, Lin, Ping, additional, Ling, Yun, additional, Liu, Bo, additional, Liu, Dongyou, additional, Liu, Guohua, additional, Liu, Huidi, additional, Liu, Jiafeng, additional, Liu, Jintao, additional, Liu, Qi, additional, Liu, Shu-Lin, additional, Liu, Taiping, additional, Liu, Tongbao, additional, Liu, Wei, additional, Liu, Yan, additional, Liu, Yanni, additional, Liu, Yisong, additional, Liu, Yuan, additional, Løbner-Olesen, Anders, additional, Loeffelholz, Michael, additional, Lu, Hongzhou, additional, Luna, Brian, additional, Ma, Bingting, additional, Ma, Chengying, additional, Ma, Shuang, additional, Ma, TianLi, additional, Madan, Rajat, additional, Mahle, Rachael E., additional, Mahlen, Steven D., additional, Malik, Satya Veer Singh, additional, Malik, Yashpal Singh, additional, Malvy, Denis, additional, Mann, Barbara J., additional, Marasini, Daya, additional, Maris, Alexander S., additional, Marjomäki, Varpu, additional, Marjuki, Henju, additional, Martín, Alberto, additional, Martín, Irene, additional, Martínez-Castillo, Moisés, additional, Martínez-Pabón, María Cecilia, additional, Mathison, Blaine A., additional, Ma’ayeh, Showgy, additional, McDowell, Andrew, additional, McLaughlin, Stephanie E., additional, McSheffrey, Gordon G., additional, Medrano, Francisco J., additional, Meehan, Conor J., additional, Mehta, Dhwani, additional, Mejía-Oquendo, Manuela, additional, Melo-Cristino, José, additional, Mendoza-Barberá, Elena, additional, Meng, Xinan, additional, Merino, Susana, additional, Merritt, Adam J., additional, Miller, Steve, additional, Miller, William R., additional, Minamino, Tohru, additional, Mirzaei, Mohammadali Khan, additional, Mora-Montes, Héctor M., additional, Mortensen, Joel, additional, Mostafa, Heba H., additional, Muhsen, Khitam, additional, Mujahed, Ahlam, additional, Muro, Antonio, additional, Murphy, Olwen C., additional, Newton, Hayley J., additional, Nguyen, April H., additional, Nichols, Wright W., additional, Niu, Siqiang, additional, Núñez, Félix, additional, Obregon, Dasiel, additional, Okamoto, Akira, additional, Okutani, Akiko, additional, Olabode, Abayomi, additional, Omar, Muna, additional, Ong, Edison, additional, Ouyang, Zhiming, additional, Pacak, Christina A., additional, Pacheco-Yépez, Judith, additional, Palmer, John, additional, Pang, Xiaoli, additional, Paredes-Sabja, Daniel, additional, Peng, Zhong, additional, Peng, Zonggen, additional, Pérez-Nevado, Francisco, additional, Poon, Art, additional, Pospíšilová, Petra, additional, Potts, Caelin C., additional, Pu, Qinqin, additional, Pujic, Petar, additional, Qi, Rui, additional, Qian, Chenyun, additional, Qian, Liu, additional, Qin, Aiping, additional, Qu, Fen, additional, Rakin, Alexander, additional, Ramesh, Ashwin, additional, Ramirez, Mario, additional, Rao, Yu, additional, Ratner, Adam J., additional, Rawool, Deepak B., additional, Rehman, Asma, additional, Ren, Jie, additional, Ren, Ping, additional, Retchless, Adam C., additional, Robertson, Erle S., additional, Rodríguez, Alicia, additional, Rodriguez, Azucena, additional, Rodríguez-Medina, Carolina, additional, Rodriguez-Nava, Veronica, additional, Rohde, Manfred, additional, Romero-Rodríguez, Alba, additional, Rosales-Morgan, Gabriela, additional, Rosenkranz, Andrea L., additional, Ruiz-Moyano, Santiago, additional, Ruokolainen, Visa, additional, Sabateen, Ali, additional, Sahu, Radhakrishna, additional, Sails, Andrew, additional, Sang, Yu, additional, Santana, Clarissa H., additional, Santos, Jesus A., additional, Santos, Renato L., additional, Schmitz, Jonathan E., additional, Serrano-Luna, Jesús, additional, Shen, Jianzhong, additional, Shen, Zhangqi, additional, Shibayama, Mineko, additional, Shirtliff, Mark E., additional, Silva-Costa, Catarina, additional, Silva-Olivares, Angélica, additional, Singh, Niraj Kumar, additional, Šmajs, David, additional, Smith, Robert P., additional, Smith, Sophie, additional, Snyder, Lori A.S., additional, Song, Yinggai, additional, Soro, Aurea Simon, additional, Spearman, Paul, additional, Spellberg, Brad, additional, Sprague, Lisa D., additional, Stratton, Charles W., additional, Strenk, Susan M., additional, Strugnell, Richard A., additional, Sun, Keer, additional, Suo, Xun, additional, Suzuki-Hatano, Silveli, additional, Svärd, Staffan, additional, Talbot, Elizabeth A., additional, Tamez-Castrellón, Alma K., additional, Tan, Nie, additional, Tang, Cynthia Y., additional, Tang, Yi-Wei, additional, Tao, Jia, additional, Tao, Lili, additional, Terrero-Salcedo, David, additional, Tharmalingam, Jayaraman, additional, Thwe, Phyu M., additional, Tiamani, Kawtar, additional, Tomás, Juan M., additional, Topaz, Nadav, additional, Tsai, Ang-Chen, additional, Tsalik, Ephraim L., additional, Tuomanen, Elaine I., additional, Turenne, Christine Y., additional, Tyagi, Anuj, additional, Uprety, Priyanka, additional, Valour, Florent, additional, van Hensbergen, Vincent P., additional, Venkatesan, Arun, additional, Vergis, Jess, additional, Villar, Margarita, additional, Vollmer, Waldemar, additional, Waites, Ken B., additional, Wan, Xiu-Feng, additional, Wang, Guiqing, additional, Wang, Lijun, additional, Wang, Lin, additional, Wang, Linqi, additional, Wang, Xiangru, additional, Wang, Xin, additional, Wang, Xinjie, additional, Wang, Ya-Ting, additional, Wang, Yang, additional, Wang, Yating, additional, Weil, Ana A., additional, Welkos, Susan L., additional, Wengenack, Nancy L., additional, Westblade, Lars F., additional, Whitfield, Chris, additional, Wu, Hui, additional, Wu, Lijuan, additional, Wu, Min, additional, Wu, Yarong, additional, Wu, Zhaowei, additional, Xiang, Ye, additional, Xiao, Di, additional, Xiao, Li, additional, Xiao, Lihua, additional, Xu, Tao, additional, Xu, Wenyue, additional, Xu, Xinping, additional, Xue, Jinling, additional, Yadav, Jay Prakash, additional, Yan, Junxiang, additional, Yan, Yixin, additional, Yang, Changmei, additional, Yang, Ruifu, additional, Yang, Ying, additional, Yao, Kaihu, additional, Yao, Yu-Feng, additional, Yeakle, Kyle C., additional, Yu, Demin, additional, Yu, Hao, additional, Yu, Xue-Jie, additional, Yuan, Zhenghong, additional, Zai, Wenjing, additional, Zhang, Jianzhong, additional, Zhang, Jing-Ren, additional, Zhang, Lanyue, additional, Zhang, Lijie, additional, Zhang, Qiwei, additional, Zhang, Wenbao, additional, Zhang, Wenhong, additional, Zhang, Xinxin, additional, Zhao, Youbao, additional, Zhou, Chuanmin, additional, Zhu, Feng, additional, Zhu, Jingting, additional, and Zhu, Yongqun, additional

Published
2024
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3. Why Am I Learning English? Spanish EFL Sports Science University Students' Motivational Orientations through the Prism of the L2 Motivational Self System

Author

Bobkina, Jelena, Gómez-Ortiz, María-José, Núñez del Río, María Cristina, and Sastre-Merino, Susana

Abstract

The study explores the motivational profiles of Spanish EFL sports science university students from the second language (L2) motivation self system (L2MSS) perspective to ultimately support Spanish higher institutions' plans committed to improving employability and competitiveness. The study analyzes the relationships between L2 motivation, L2 proficiency, gender, and L2 contextual variables using data from 196 English as a foreign language (EFL) sports science university students. The data reveal that the ideal L2 self construct stands out as the most salient and powerful factor, while the ought-to and rebellious L2 selves are less significant and there are items loading on both of them at the same time. Thus, higher means for the ideal L2 self motivation correspond to higher levels of L2 proficiency and are supported by L2 learning contextual variables. The strongest ought-to L2 self was registered in students with mid-low L2 proficiency and a lack of L2 learning experiences. Meanwhile, the rebellious L2 self is clearly distinguishable only for students with high L2 proficiency. Pedagogical and curricular implications of these findings are that the ideal and the rebellious L2 selves could positively predict students' L2 proficiency. Thus, new dynamics of education should explore language teaching methodologies that are more likely to enhance students' ideal and rebellious L2 selves.

Published
2021

8. Literature and Language Education: Exploring Teachers' Views on Teaching Foreign Language through Literature in Bilingual Secondary Schools in Madrid (Spain)

Author

Bobkina, Jelena, Romero, Elena Domínguez, and Sastre-Merino, Susana

Abstract

This study explores the perceptions of English language teachers of the use of literature in the context of bilingual secondary education in the region of Madrid (Spain). An approach was adopted under which eighty-one English teacher participants completed a questionnaire so that a quantitative methodological approach of a descriptive-correlational nature could be adopted for this study. Results unveiled teacher perceptions of the benefits and drawbacks of using literary texts as a teaching and learning tool, their selection of literary texts and their actual implementation of these texts in their English classes, as well as the training needs for the effective use of literary texts as a language teaching and learning tool in the bilingual EFL secondary classroom. The pedagogical implications of the study emphasize the need to redesign and consolidate teacher training programmes containing literature and innovative teaching aspects both in initial teacher training programmes and for continued training.

Published
2021
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15. Incidence of myeloid neoplasms in Spain (2002–2013): a population-based study of the Spanish network of cancer registries

Author

Solans, Marta, Sanvisens, Arantza, Ameijide, Alberto, Merino, Susana, Rojas, Dolores, Alemán, Araceli, Banqueri, Emilia, Chico, Matilde, Marcos, Ana Isabel, de Castro, Visitación, Gil, Leire, de Munain, Arantza López, Puigdemont, Montse, Sánchez, Maria-José, Perucha, Josefina, Ruiz-Armengol, Patricia, Chirlaque, Mª Dolores, Guevara, Marcela, Carulla, Marià, and Marcos-Gragera, Rafael

Published
2022
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17. Proposals for Improving Assessment Systems in Higher Education: An Approach from the Model 'Working with People'

Author

de los Ríos-Carmenado, I., Sastre-Merino, Susana, Fernández Jiménez, Consuelo, Núñez del Río, Mª Cristina, Reyes Pozo, Encarnación, and García Arjona, Noemi

Abstract

The European Higher Education Area (EHEA) represents a challenge to university teachers to adapt their assessment systems, directing them towards continuous assessment. The integration of competence-based learning as an educational benchmark has also led to a perspective more focused on student and with complex learning situations closer to reality. However, its assessment entails an increase in lecturers' workload and a continuous demand for students due to the diversity of assessment tests required to assess each aspect of competences. After a period in which those changes have been introduced, the Technical University of Madrid (UPM) considered to analyse the assessment systems and the ways to improve them, at both bachelor's and master's degree programmes. The methodology used is based on the model "Working with People", which for the first time at the UPM, creates a participatory process with students and lecturers aimed at knowing their opinion and their feelings about the assessment process and the potential for improvement. Eight WWW-workshops were developed, with 32 students and 39 university teachers in total. The results indicate that the perception of students and lecturers regarding the assessment systems have many common points, as well as the need to undertake an improvement strategy for integrating actions from all three model dimensions, seeking a balance in joint work among lecturers, university administrators and students. This work has been performed within the framework of educational innovations cross-cutting project named "Analysis of the UPM Degree Programmes Evaluation Procedures and Proposal for Improvements" (EVALÚA), supported by the Educational Innovation Department.

Published
2016

20. Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistance

Author

Prieto, Alejandro, primary, Miró, Lluïsa, additional, Margolles, Yago, additional, Bernabeu, Manuel, additional, Salguero, David, additional, Merino, Susana, additional, Tomás, Joan, additional, Corbera, Juan Alberto, additional, Pérez-Bosque, Anna, additional, Hüttener, Mário, additional, Fernández, Luis Ángel, additional, and Juárez, Antonio, additional

Published
2023
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21. Nanoindentation applied to ion-irradiated and neutron-irradiated Fe-9Cr and Fe-9Cr-NiSiP model alloys.

Author

Bergner, Frank, Kaden, Cornelia, Das, Aniruddh, Merino, Susana, Diego, Gonzalo, and Hähner, Peter

Subjects
NANOINDENTATION, ALLOYS, VICKERS hardness, NEUTRON irradiation, INDENTATION (Materials science), HARDNESS, NUMBER theory
Abstract

Nanoindentation of ion-irradiated materials has attracted much interest as a tool envisaged to derive the dose dependence of bulk-equivalent hardness from small samples. A major challenge arises from the steep damage gradient in the thin ion-irradiated layer and its unavoidable interplay with the indentation size effect. The present study relies on a number of choices aimed at simplifying the interpretation of the results and strengthening the conclusions. The studied alloys are two ferritic Fe-9Cr model alloys differing in controlled amounts of Ni, Si, and P known to enhance irradiation hardening. Both ion-irradiated (5 MeV Fe2+ ions) and neutron-irradiated samples along with the unirradiated references were investigated using Berkovich tips. According to the collaborative nature of the study, tests were conducted in two different laboratories using different equipment. A generalized Nix–Gao approach was applied to derive the bulk-equivalent hardness and characteristic length scale parameters for the homogeneous unirradiated and neutron-irradiated samples. Comparison with Vickers hardness indicates a 6% overestimation of the bulk-equivalent hardness as compared to the ideal correlation. For the case of ion irradiation, a first model assumes a homogeneous irradiated layer on a homogeneous substrate, while a second model explicitly takes into account the damage gradient. The first model was combined with both the original and the generalized Nix–Gao relation. We have found that the results revealed for Fe-9Cr vs Fe-9Cr-NiSiP are compatible with expectations based upon known irradiation-induced microstructures. The bulk-equivalent hardness derived for ion-irradiated samples reasonably agrees with the observation for neutron-irradiated samples. [ABSTRACT FROM AUTHOR]

Published
2022
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24. Consumption of Fish Is Not Associated with Risk of Differentiated Thyroid Carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study

Author

Zamora-Ros, Raul, Castañeda, Jazmín, Rinaldi, Sabina, Cayssials, Valerie, Slimani, Nadia, Weiderpass, Elisabete, Tsilidis, Konstantinos K, Boutron-Ruault, Marie-Christine, Overvad, Kim, Eriksen, Anne K, Tjønneland, Anne, Kühn, Tilman, Katzke, Verena, Boeing, Heiner, Trichopoulou, Antonia, La Vecchia, Carlo, Kotanidou, Anastasia, Palli, Domenico, Grioni, Sara, Mattiello, Amalia, Tumino, Rosario, Sciannameo, Veronica, Lund, Eiliv, Merino, Susana, Salamanca-Fernández, Elena, Amiano, Pilar, Huerta, José María, Barricarte, Aurelio, Ericson, Ulrika, Almquist, Martin, Hennings, Joakim, Sandström, Maria, Bueno-de-Mesquita, H Bas, Peeters, Petra H, Khaw, Kay-Tee, Wareham, Nicholas J, Schmidt, Julie A, Cross, Amanda J, Riboli, Elio, Scalbert, Augustin, Romieu, Isabelle, Agudo, Antonio, and Franceschi, Silvia

Published
2017
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26. Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses

Author

Seyed Khoei, Nazlisadat, Jenab, Mazda, Murphy, Neil, Banbury, Barbara L., Carreras-Torres, Robert, Viallon, Vivian, Kühn, Tilman, Bueno-de-Mesquita, Bas, Aleksandrova, Krasimira, Cross, Amanda J., Weiderpass, Elisabete, Stepien, Magdalena, Bulmer, Andrew, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Severi, Gianluca, Carbonnel, Franck, Katzke, Verena, Boeing, Heiner, Bergmann, Manuela M., Trichopoulou, Antonia, Karakatsani, Anna, Martimianaki, Georgia, Palli, Domenico, Tagliabue, Giovanna, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, Skeie, Guri, Merino, Susana, Bonet, Catalina, Rodríguez-Barranco, Miguel, Gil, Leire, Chirlaque, Maria-Dolores, Ardanaz, Eva, Myte, Robin, Hultdin, Johan, Perez-Cornago, Aurora, Aune, Dagfinn, Tsilidis, Konstantinos K., Albanes, Demetrius, Baron, John A., Berndt, Sonja I., Bézieau, Stéphane, Brenner, Hermann, Campbell, Peter T., Casey, Graham, Chan, Andrew T., Chang-Claude, Jenny, Chanock, Stephen J., Cotterchio, Michelle, Gallinger, Steven, Gruber, Stephen B., Haile, Robert W., Hampe, Jochen, Hoffmeister, Michael, Hopper, John L., Hsu, Li, Huyghe, Jeroen R., Jenkins, Mark A., Joshi, Amit D., Kampman, Ellen, Larsson, Susanna C., Le Marchand, Loic, Li, Christopher I., Li, Li, Lindblom, Annika, Lindor, Noralane M., Martín, Vicente, Moreno, Victor, Newcomb, Polly A., Offit, Kenneth, Ogino, Shuji, Parfrey, Patrick S., Pharoah, Paul D. P., Rennert, Gad, Sakoda, Lori C., Schafmayer, Clemens, Schmit, Stephanie L., Schoen, Robert E., Slattery, Martha L., Thibodeau, Stephen N., Ulrich, Cornelia M., van Duijnhoven, Franzel J. B., Weigl, Korbinian, Weinstein, Stephanie J., White, Emily, Wolk, Alicja, Woods, Michael O., Wu, Anna H., Zhang, Xuehong, Ferrari, Pietro, Anton, Gabriele, Peters, Annette, Peters, Ulrike, Gunter, Marc J., Wagner, Karl-Heinz, and Freisling, Heinz

Published
2020
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32. Incidence and survival of lymphoid neoplasms in Spain, 2002-2013: A population-based study from the Spanish Network of Cancer Registries (REDECAN)

Author

Pla, Clàudia, Solans, Marta, Ameijide, Alberto, Sanvisens, Arantza, Carulla, Marià, Rojas, María Dolores, Alemán, María Araceli, Sáez-Lloret, Isabel, Díaz-Del-Campo, Cristina, Marcos-Navarro, Ana Isabel, Sainz-de-Aja, Leire, Aizpurua-Atxega, Amaia, Lopez-de-Munain, Arantza, Sánchez, Maria-José, Perucha, Josefina, Franch, Paula, Chirlaque, María-Dolores, Guevara, Marcela, Galceran, Jaume, Merino, Susana, Marcos-Gragera, Rafael, and REDECAN working group

Subjects
Cancer Research, Oncology, Survival, Spain, Incidence, Trends, Population-based, Lymphoid neoplasms
Abstract

Introduction: The aim of this study was to describe incidence, incidence trends and survival patterns of lymphoid neoplasms (LNs) and its subtypes in Spain in the period 2002-2013 using data from the Spanish Network of Cancer Registries (REDECAN). Materials and Methods: Data were extracted from 13 Spanish populationbased cancer registries. LNs incident cases were codified using the International Classification of Diseases for Oncology, third edition (ICD-O-3) and grouped according to the WHO 2008 classification. Age-standardized incidence rates to the 2013 European standard population (ASIRe) were obtained. Poisson regression models were used to analyze trends in incidence rates and estimate the annual percentage change (APC) for each subtype. The number of cases in Spain for 2023 was estimated by applying the estimated age-specific rates for the year 2023 to the 2023 Spanish population. Observed survival (OS) was estimated by the Kaplan-Meier method and net survival (NS) by the Pohar-Perme method. Sex- and age-specific estimates of 5-year NS were calculated, as well as its changes according to two periods of diagnosis (2002-2007 and 2008-2013). Results: LNs accounted for 69% (n=39,156) of all hematological malignancies (n=56,751) diagnosed during the period of study. Median age at diagnosis was 67 years (interquartile range (IQR) = 52-77). The overall ASIRe was 34.23 (95% confidence interval (CI): 33.89, 34.57) and showed a marked male predominance in almost all subtypes (global sex ratio = 1.45). During the study period, incidence trends of LNs remained stable (APC: 0.3; 95% CI: -0.1, 0.6), nevertheless some subtypes showed statistically significant variations, such as LNs NOS category (APC: -5.6; 95% CI: -6.8, -4.3). Around 17,926 new cases of LNs will be diagnosed in 2023 in Spain. Survival rates differed considerably across age-groups, while they were similar between men and women. Five- year NS was 62.81% (95% CI: 62.1, 63.52) for all LNs, and varied widely across LNs subtypes, ranging from 39.21% to 90.25%. NS for all LNs improved from the first period of diagnosis to the second one, being 61.57% (95% CI: 60.56, 62.61) in 2002-2007 and 64.17% (95% CI: 63.29, 65.07) in 2008-2013. Conclusions: This study presents the first complete and extensive populationbased analysis of LNs incidence and survival in Spain. These population-based data provide relevant information to better understand the epidemiology of LNs in Southern Europe and it features some useful points for public health authorities and clinicians. However, additional improvements regarding the registration of these hematological neoplasms can be implemented., Josep Carreras Leukaemia Research Institute FIJC1100

Published
2022

33. Consumption of fruits, vegetables and fruit juices and differentiated thyroid carcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Author

Zamora‐Ros, Raul, Béraud, Virginie, Franceschi, Silvia, Cayssials, Valerie, Tsilidis, Konstantinos K., Boutron‐Ruault, Marie‐Christine, Weiderpass, Elisabete, Overvad, Kim, Tjønneland, Anne, Eriksen, Anne K., Bonnet, Fabrice, Affret, Aurélie, Katzke, Verena, Kühn, Tilman, Boeing, Heiner, Trichopoulou, Antonia, Valanou, Elisavet, Karakatsani, Anna, Masala, Giovanna, Grioni, Sara, Santucci de Magistris, Maria, Tumino, Rosario, Ricceri, Fulvio, Skeie, Guri, Parr, Christine L, Merino, Susana, Salamanca‐Fernández, Elena, Chirlaque, Maria‐Dolores, Ardanaz, Eva, Amiano, Pilar, Almquist, Martin, Drake, Isabel, Hennings, Joakim, Sandström, Maria, Bueno‐de‐Mesquita, H. B(as), Peeters, Petra H., Khaw, Kay‐Thee, Wareham, Nicholas J., Schmidt, Julie A., Perez‐Cornago, Aurora, Aune, Dagfinn, Riboli, Elio, Slimani, Nadia, Scalbert, Augustin, Romieu, Isabelle, Agudo, Antonio, and Rinaldi, Sabina

Published
2018
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34. Racionalismo constructivista: fundamento filosófico del secreto bancario

Author

Merino, Susana Fabiola García and Cairo, Vladimir Rodríguez

Subjects
built order, constructivist rationalism, financial system, bank secrecy, orden construido, racionalismo constructivista, sistema financiero, secreto bancario
Abstract

La investigación analizó desde la perspectiva filosófica del racionalismo constructivista de Hayek, los fundamentos constructivistas del secreto bancario, enmarcándolo como un mecanismo de protección del sistema financiero, sistema que, si bien aparece como un orden espontáneo por la necesidad de diversos individuos de contar con un mecanismo de ahorro y financiamiento, actualmente al encontrarse sujeto a determinadas reglas de juego y a una supervisión específica por parte de las autoridades gubernamentales, es considerado un orden construido que busca con relación al secreto bancario, salvaguardar la información sobre el ahorro de los individuos a fin de que éstos puedan contar con un respaldo patrimonial.

Published
2022
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36. Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma

Author

Stepien, Magdalena Lopez-Nogueroles, Marina Lahoz, Agustin and Kuehn, Tilman Perlemuter, Gabriel Voican, Cosmin Ciocan, Dragos Boutron-Ruault, Marie-Christine Jansen, Eugene and Viallon, Vivian Leitzmann, Michael Tjonneland, Anne Severi, Gianluca Mancini, Francesca Romana Dong, Catherine Kaaks, Rudolf Fortner, Renee Turzanski Bergmann, Manuela M. Boeing, Heiner Trichopoulou, Antonia Karakatsani, Anna Peppa, Eleni and Palli, Domenico Krogh, Vittorio Tumino, Rosario and Sacerdote, Carlotta Panico, Salvatore Bueno-de-Mesquita, H. Bas and Skeie, Guri Merino, Susana Ros, Raul Zamora Sanchez, Maria Jose Amiano, Pilar Huerta, Jose Ma Barricarte, Aurelio and Sjoeberg, Klas Ohlsson, Bodil Nystroem, Hanna Werner, Marten Perez-Cornago, Aurora Schmidt, Julie A. Freisling, Heinz Scalbert, Augustin Weiderpass, Elisabete Christakoudi, Sofia Gunter, Marc J. Jenab, Mazda

Subjects
education
Abstract

Bile acids (BAs) play different roles in cancer development. Some are carcinogenic and BA signaling is also involved in various metabolic, inflammatory and immune-related processes. The liver is the primary site of BA synthesis. Liver dysfunction and microbiome compositional changes, such as during hepatocellular carcinoma (HCC) development, may modulate BA metabolism increasing concentration of carcinogenic BAs. Observations from prospective cohorts are sparse. We conducted a study (233 HCC case-control pairs) nested within a large observational prospective cohort with blood samples taken at recruitment when healthy with follow-up over time for later cancer development. A targeted metabolomics method was used to quantify 17 BAs (primary/secondary/tertiary; conjugated/unconjugated) in prediagnostic plasma. Odd ratios (OR) for HCC risk associations were calculated by multivariable conditional logistic regression models. Positive HCC risk associations were observed for the molar sum of all BAs (ORdoubling = 2.30, 95% confidence intervals [CI]: 1.76-3.00), and choline- and taurine-conjugated BAs. Relative concentrations of BAs showed positive HCC risk associations for glycoholic acid and most taurine-conjugated BAs. We observe an association between increased HCC risk and higher levels of major circulating BAs, from several years prior to tumor diagnosis and after multivariable adjustment for confounders and liver functionality. Increase in BA concentration is accompanied by a shift in BA profile toward higher proportions of taurine-conjugated BAs, indicating early alterations of BA metabolism with HCC development. Future studies are needed to assess BA profiles for improved stratification of patients at high HCC risk and to determine whether supplementation with certain BAs may ameliorate liver dysfunction.

Published
2022

42. Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma

Author

Stepien, Magdalena, primary, Lopez‐Nogueroles, Marina, additional, Lahoz, Agustin, additional, Kühn, Tilman, additional, Perlemuter, Gabriel, additional, Voican, Cosmin, additional, Ciocan, Dragos, additional, Boutron‐Ruault, Marie‐Christine, additional, Jansen, Eugene, additional, Viallon, Vivian, additional, Leitzmann, Michael, additional, Tjønneland, Anne, additional, Severi, Gianluca, additional, Mancini, Francesca Romana, additional, Dong, Catherine, additional, Kaaks, Rudolf, additional, Fortner, Renee Turzanski, additional, Bergmann, Manuela M., additional, Boeing, Heiner, additional, Trichopoulou, Antonia, additional, Karakatsani, Anna, additional, Peppa, Eleni, additional, Palli, Domenico, additional, Krogh, Vittorio, additional, Tumino, Rosario, additional, Sacerdote, Carlotta, additional, Panico, Salvatore, additional, Bueno‐de‐Mesquita, H. Bas, additional, Skeie, Guri, additional, Merino, Susana, additional, Ros, Raul Zamora, additional, Sánchez, Maria Jose, additional, Amiano, Pilar, additional, Huerta, Jose Mª, additional, Barricarte, Aurelio, additional, Sjöberg, Klas, additional, Ohlsson, Bodil, additional, Nyström, Hanna, additional, Werner, Marten, additional, Perez‐Cornago, Aurora, additional, Schmidt, Julie A., additional, Freisling, Heinz, additional, Scalbert, Augustin, additional, Weiderpass, Elisabete, additional, Christakoudi, Sofia, additional, Gunter, Marc J., additional, and Jenab, Mazda, additional

Published
2022
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