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3. COVID-19 Lockdown Effects on Sleep, Immune Fitness, Mood, Quality of Life, and Academic Functioning: Survey Data from Turkish University Students

Author

Afd Pharmacology, Pharmacology, Hendriksen, Pauline A., Tan, Sema, van Oostrom, Evi C., Merlo, Agnese, Bardakçi, Hilal, Aksoy, Nilay, Garssen, Johan, Bruce, Gillian, Verster, Joris C., Afd Pharmacology, Pharmacology, Hendriksen, Pauline A., Tan, Sema, van Oostrom, Evi C., Merlo, Agnese, Bardakçi, Hilal, Aksoy, Nilay, Garssen, Johan, Bruce, Gillian, and Verster, Joris C.

Published
2024

4. Proceedings of the 12th Alcohol Hangover Research Group Meeting, in Buenos Aires, Argentina

Author

Tellez-Monnery, Kristin, primary, Balikji, Jessica, additional, Carrere, Lautaro, additional, Czerniczyniec, Analia, additional, Devenney, Lydia E., additional, Guerra, Juan I., additional, Kiani, Pantea, additional, Lores-Arnaiz, Silvia, additional, Merlo, Agnese, additional, Stock, Ann-Kathrin, additional, Verster, Joris C., additional, and Karadayian, Analia, additional

Published
2024
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5. COVID-19 Lockdown Effects on Sleep, Immune Fitness, Mood, Quality of Life, and Academic Functioning: Survey Data from Turkish University Students.

Author

Hendriksen, Pauline A., Tan, Sema, van Oostrom, Evi C., Merlo, Agnese, Bardakçi, Hilal, Aksoy, Nilay, Garssen, Johan, Bruce, Gillian, and Verster, Joris C.

Subjects
TURKS, QUALITY of life, COVID-19, STAY-at-home orders, COLLEGE students
Abstract

Previous studies from the Netherlands, Germany, and Argentina revealed that the 2019 coronavirus disease (COVID-19) pandemic and associated lockdown periods had a significant negative impact on the wellbeing and quality of life of students. The negative impact of lockdown periods on health correlates such as immune fitness, alcohol consumption, and mood were reflected in their academic functioning. As both the duration and intensity of lockdown measures differed between countries, it is important to replicate these findings in different countries and cultures. Therefore, the purpose of the current study was to examine the impact of the COVID-19 pandemic on immune fitness, mood, academic functioning, sleep, smoking, alcohol consumption, healthy diet, and quality of life among Turkish students. Turkish students in the age range of 18 to 30 years old were invited to complete an online survey. Data were collected from n = 307 participants and included retrospective assessments for six time periods: (1) BP (before the COVID-19 pandemic, 1 January 2020–10 March 2020), (2) NL1 (the first no lockdown period, 11 March 2020–28 April 2021), (3) the lockdown period (29 April 2021–17 May 2021), (4) NL2 (the second no lockdown period, 18 May 2021–31 December 2021), (5) NL3 (the third no lockdown period, 1 January 2022–December 2022), and (6) for the past month. In this data descriptor article, the content of the survey and the dataset are described. Dataset: The dataset is submitted as a Supplementary File. Dataset License: CC0 [ABSTRACT FROM AUTHOR]

Published
2024
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6. Absenteeism, Presenteeism, and the Economic Costs of Alcohol Hangover in The Netherlands.

Author

Severeijns, Noortje R., Sips, Annabel S. M., Merlo, Agnese, Bruce, Gillian, and Verster, Joris C.

Subjects
PRESENTEEISM (Labor), LABOR productivity, JOB absenteeism, ALCOHOLIC intoxication, MEMORY bias, EMPLOYEES, ALCOHOL drinking, STATISTICAL sampling, JOB performance
Abstract

The alcohol hangover is defined as the combination of negative mental and physical symptoms that can be experienced after a single episode of alcohol consumption, starting when the blood alcohol concentration (BAC) approaches zero. Alcohol hangover symptoms such as fatigue, nausea, and headache can negatively affect daily activities, including work performance. The alcohol hangover can therefore be a cause of both absenteeism (not going to work) and presenteeism (going to work while hungover). An online survey among a convenience sample of n = 347 Dutch adults examined the number of days of absenteeism and presenteeism associated with having a hangover as well as the loss of productivity when going to work when hungover during the year 2019. In the Dutch sample, 8.1% of employees reported one or more days of absenteeism due to hangover in 2019, and 33.4% reported one or more days of presenteeism. The analyses revealed that alcohol hangover was associated with 0.2 days of absenteeism and 8.3 days of presenteeism and a productivity loss of 24.9% on days worked with a hangover. The estimated associated costs for the Dutch economy in 2019 of absenteeism (EUR 234,538,460) and presenteeism (EUR 2,423,603,184) total EUR 2,658,141,644. In conclusion, the alcohol hangover is associated with absenteeism, presenteeism, and reduced performance at work while hungover. As such, the annual costs of the alcohol hangover have a significant impact on the Dutch economy. However, these first findings on the economic costs of the alcohol hangover should be considered a rough estimate. They should be verified in a longitudinal study to minimize recall bias, including a nationally representative sample of sufficient sample size. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Proceedings of the 12th Alcohol Hangover Research Group Meeting, in Buenos Aires, Argentina †.

Author

Tellez-Monnery, Kristin, Balikji, Jessica, Carrere, Lautaro, Czerniczyniec, Analia, Devenney, Lydia E., Guerra, Juan I., Kiani, Pantea, Lores-Arnaiz, Silvia, Merlo, Agnese, Stock, Ann-Kathrin, Verster, Joris C., and Karadayian, Analia

Subjects
HANGOVERS, RESEARCH teams, ANNUAL meetings
Abstract

The current proceedings summarize the presentations held during the 12th meeting of the Alcohol Hangover Research Group (AHRG) in 2022, in Buenos Aires, Argentina. The aim of the annual AHRG meeting was to discuss advances in research on the causes, consequences, and possible treatment of the alcohol hangover, including methodological issues and the possibilities for future research collaboration. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Alcohol Consumption, Hangovers, and Smoking among Buenos Aires University Students during the COVID-19 Pandemic

Author

Afd Pharmacology, Pharmacology, Karadayian, Analia, Merlo, Agnese, Czerniczyniec, Analia, Lores-Arnaiz, Silvia, Hendriksen, Pauline A., Kiani, Pantea, Bruce, Gillian, Verster, Joris C., Afd Pharmacology, Pharmacology, Karadayian, Analia, Merlo, Agnese, Czerniczyniec, Analia, Lores-Arnaiz, Silvia, Hendriksen, Pauline A., Kiani, Pantea, Bruce, Gillian, and Verster, Joris C.

Published
2023

11. An evening of alcohol consumption negatively impacts next-day immune fitness in both hangover-sensitive drinkers and hangover-resistant drinkers

Author

Afd Pharmacology, Pharmacology, Merlo, Agnese, Mackus, Marlou, van de Loo, Aurora J.A.E., van Neer, Renier H.P., Vermeulen, Sterre A., Thijssen, Suzan S., Knipping, Karen, Bruce, Gillian, Garssen, Johan, Verster, Joris C., Afd Pharmacology, Pharmacology, Merlo, Agnese, Mackus, Marlou, van de Loo, Aurora J.A.E., van Neer, Renier H.P., Vermeulen, Sterre A., Thijssen, Suzan S., Knipping, Karen, Bruce, Gillian, Garssen, Johan, and Verster, Joris C.

Published
2023

12. Depression, Anxiety, and Stress among Hangover-Sensitive and Hangover-Resistant Drinkers

Author

Pharmacology, Afd Pharmacology, Kim, Andy J, Merlo, Agnese, Mackus, Marlou, Bruce, Gillian, Johnson, Sean J, Alford, Chris, Sherry, Simon B, Stewart, Sherry H, Verster, Joris C, Pharmacology, Afd Pharmacology, Kim, Andy J, Merlo, Agnese, Mackus, Marlou, Bruce, Gillian, Johnson, Sean J, Alford, Chris, Sherry, Simon B, Stewart, Sherry H, and Verster, Joris C

Published
2023

13. Emotion Regulation and Mood during the COVID-19 Pandemic

Author

Pharmacology, Afd Pharmacology, Verster, Joris C, Hendriksen, Pauline A, Kiani, Pantea, Merlo, Agnese, Balikji, Jessica, Garssen, Johan, Bruce, Gillian, Pharmacology, Afd Pharmacology, Verster, Joris C, Hendriksen, Pauline A, Kiani, Pantea, Merlo, Agnese, Balikji, Jessica, Garssen, Johan, and Bruce, Gillian

Published
2023

18. Immune Fitness and the Psychosocial and Health Consequences of the COVID-19 Pandemic Lockdown in The Netherlands: Methodology and Design of the CLOFIT Study

Author

Kiani, Pantea, Merlo, Agnese, Saeed, Hama M., Benson, Sarah, Bruce, Gillian, Hoorn, Rosalie, Kraneveld, Aletta D., van de Loo, Aurora J.A.E., Severeijns, Noortje R., Sips, Annabel S.M., Scholey, Andrew, Garssen, Johan, Verster, Joris C., Afd Pharmacology, dIRAS RA-1, Pharmacology, Afd Pharmacology, dIRAS RA-1, and Pharmacology

Subjects
Gerontology, Immune fitness, Coronavirus disease 2019 (COVID-19), mood, alcohol consumption, Population, lcsh:BF1-990, Ethnic group, Pain, Disease, lockdown, 03 medical and health sciences, Study Protocol, 0302 clinical medicine, Pandemic, Lockdown, Mood, Developmental and Educational Psychology, Alcohol consumption, pain, 030212 general & internal medicine, education, Applied Psychology, education.field_of_study, lcsh:Public aspects of medicine, COVID-19, lcsh:RA1-1270, Clinical Psychology, lcsh:Psychology, Cohort, immune fitness, Psychology, Psychosocial, 030217 neurology & neurosurgery
Abstract

This article provides an overview of the design and methodology of the “Corona lockdown: how fit are you?” (CLOFIT) study, including the questionnaires and scales that were included in the online survey. The aim of the CLOFIT study was to investigate the psychosocial and health consequences of the coronavirus disease 2019 (COVID-19) pandemic in the Netherlands. The survey was conducted among the Dutch population to collect data on immune fitness and the psychological and health consequences of the 2019 coronavirus disease (COVID-19) pandemic lockdown in the Netherlands. The CLOFIT dataset contains measures from N = 1910 participants and is broadly representative of the Dutch general population. The dataset represents both sexes, a range of ages including the elderly, different education levels, and ethnic backgrounds. The cohort also includes people with a diverse health status and range of medication use.

Published
2021

21. COVID-19 Lockdown Effects on Academic Functioning, Mood, and Health Correlates: Data from Dutch Pharmacy Students, PhD Candidates and Postdocs

Author

Hendriksen, Pauline A., Merlo, Agnese, Bijlsma, Elisabeth Y., Engels, Ferdi, Garssen, Johan, Bruce, Gillian, Verster, Joris C., Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology

Subjects
Quality of life, Gerontology, Information Systems and Management, Coronavirus disease 2019 (COVID-19), mood, Pharmacy, Academic performance, Social interactions, Bibliography. Library science. Information resources, lockdown, Quality of life (healthcare), Lockdown, Mood, Pandemic, Alcohol consumption, Online education, Response rate (survey), Sleep quality, business.industry, academic performance, COVID-19, Computer Science Applications, online education, social interactions, Hangover, Sleep, business, Psychology, Information Systems
Abstract

Mixed results have been published on the impact of the 2019 coronavirus (COVID-19) pandemic and its associated lockdown periods on academic functioning, mood, and health correlates such as alcohol consumption. Whereas a number of students report an impaired academic performance and increased alcohol intake during lockdown periods, other students report no change or an improvement in academic functioning and a reduced alcohol consumption. This data descriptor article describes the dataset of a study investigating the impact of the COVID-19 pandemic on academic functioning. To investigate this, an online survey was conducted among Dutch pharmacy students, PhD candidates and postdoctoral researchers (postdocs) of Utrecht University, the Netherlands. Compared to before the COVID-19 pandemic, the survey assessed possible changes in self-reported academic functioning, mood and health correlates such as alcohol consumption, perceived immune functioning and sleep quality. Retrospective assessments were made for four periods, including (1) the year 2019 (the period before COVID-19), (2) the first lockdown period (15 March–11 May 2020), (3) summer 2020 (no lockdown) and (4) the second lockdown (November 2020–April 2021). This article describes the content of the survey and corresponding dataset. The survey had a response rate of 24.3% and was completed by 345 participants.

Published
2021

22. Mood and Changes in Alcohol Consumption in Young Adults during COVID-19 Lockdown: A Model Explaining Associations with Perceived Immune Fitness and Experiencing COVID-19 Symptoms

Author

Merlo, Agnese, Severeijns, Noortje R, Benson, Sarah, Scholey, Andrew, Garssen, Johan, Bruce, Gillian, Verster, Joris C, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology

Subjects
Adult, Adolescent, Alcohol Drinking, Coronavirus disease 2019 (COVID-19), social isolation, Health, Toxicology and Mutagenesis, alcohol consumption, mood, Anxiety, Article, Young Adult, stress, Immune system, medicine, Humans, Young adult, Depression (differential diagnoses), Aged, SARS-CoV-2, business.industry, Public Health, Environmental and Occupational Health, COVID-19, Loneliness, Mood, Communicable Disease Control, Cohort, Medicine, medicine.symptom, immune fitness, business, Demography
Abstract

The aim of this study was to explore the effects of the 2019 Coronavirus (COVID-19) lockdown on mood states, stress, alcohol consumption and perceived immune fitness in a Dutch sample. Analysis included a subsample from the “Corona Lockdown: how fit are you?” (CLOFIT) study, comprising N = 761 participants who reported consuming alcohol in 2020. Results show that, compared to pre-lockdown, the first COVID-19 lockdown (March 2020) was associated with experiencing poorer mood (e.g., anxiety, depression, loneliness, fatigue) and increased stress levels. Among younger participants (18 to 35 years old), a significant decrease in weekly alcohol consumption was found during COVID-19 lockdown, which was not significant in older individuals. For the younger age cohort (18 to 35 years old), increased stress significantly correlated to increased weekly alcohol consumption (r = 0.163, p = 0.003), which in turn, correlated significantly to reporting a poorer perceived immune fitness (r = −0.165, p = 0.002). Poorer perceived immune fitness correlated significantly with increases in the presence and severity of COVID-19 symptoms (r = −0.313, p &lt, 0.001, and r = −0.325, p &lt, 0.001, respectively). The data provides evidence for significant relationships between changes in mood, stress and alcohol consumption during COVID-19 lockdown, and supports a model that links these changes to perceived immune fitness and susceptibility to experiencing COVID-19 symptoms.

Published
2021

23. Alcohol Consumption Patterns during COVID-19 Lockdown and Their Relationship with Perceived Immune Fitness and Reported COVID-19 Symptoms

Author

Merlo, Agnese, Hendriksen, Pauline A, Severeijns, Noortje R, Garssen, Johan, Bruce, Gillian, Verster, Joris C, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology

Subjects
Coronavirus disease 2019 (COVID-19), Leadership and Management, mood, Health Informatics, Alcohol, Article, Stress level, chemistry.chemical_compound, stress, Immune system, Health Information Management, Environmental health, Medicine, Social isolation, Drinking behaviour, business.industry, alcohol, Health Policy, COVID-19, Mood, perceived immune fitness, chemistry, medicine.symptom, business, Alcohol consumption
Abstract

Since the outbreak of the 2019 coronavirus (COVID-19) pandemic, lockdown periods have been installed to counteract the spread of the virus. These lockdowns, characterized by social isolation, have been associated with mood changes and increased stress. Individuals have used various strategies to cope with the negative effects of being in lockdown, including increasing the frequency and quantity of alcohol consumption. The aim of this study was to investigate mood before and during lockdown of individuals who reported consuming more, less, or the same amount of alcohol during lockdown, and examine how this impacts and perceived immune fitness and the presence and severity of COVID-19 symptoms. Analysis included a sub-sample from the ‘Corona Lockdown: how fit are you?’ (CLOFIT) study, comprising N = 761 participants who reported consuming alcohol in 2020. The results of the online survey showed that half of the participants did not alter their weekly alcohol consumption during lockdown (50.4%), whereas 25.9% of drinkers reported a reduction and 23.8% reported an increase in weekly alcohol consumption. Compared to individuals that did not alter their drinking behaviour, both increased and reduced alcohol consumption during lockdown was associated with poorer mood and higher stress levels. Increased alcohol consumption was associated with significantly reduced perceived immune fitness and a high presence and severity of COVID-19 symptoms. This effect was not significant among individuals with reduced or unaltered alcohol consumption.

Published
2021

26. Immune fitness and the psychosocial and health consequences of the covid-19 pandemic lockdown in the netherlands: Methodology and design of the clofit study

Author

Afd Pharmacology, dIRAS RA-1, Pharmacology, Kiani, Pantea, Merlo, Agnese, Saeed, Hama M., Benson, Sarah, Bruce, Gillian, Hoorn, Rosalie, Kraneveld, Aletta D., van de Loo, Aurora J.A.E., Severeijns, Noortje R., Sips, Annabel S.M., Scholey, Andrew, Garssen, Johan, Verster, Joris C., Afd Pharmacology, dIRAS RA-1, Pharmacology, Kiani, Pantea, Merlo, Agnese, Saeed, Hama M., Benson, Sarah, Bruce, Gillian, Hoorn, Rosalie, Kraneveld, Aletta D., van de Loo, Aurora J.A.E., Severeijns, Noortje R., Sips, Annabel S.M., Scholey, Andrew, Garssen, Johan, and Verster, Joris C.

Published
2021

29. Mood and Changes in Alcohol Consumption in Young Adults during COVID-19 Lockdown: A Model Explaining Associations with Perceived Immune Fitness and Experiencing COVID-19 Symptoms

Author

Afd Pharmacology, Pharmacology, Merlo, Agnese, Severeijns, Noortje R, Benson, Sarah, Scholey, Andrew, Garssen, Johan, Bruce, Gillian, Verster, Joris C, Afd Pharmacology, Pharmacology, Merlo, Agnese, Severeijns, Noortje R, Benson, Sarah, Scholey, Andrew, Garssen, Johan, Bruce, Gillian, and Verster, Joris C

Published
2021

31. Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover

Author

Verster, Joris C, Kruisselbrink, L Darren, Slot, Karin A, Anogeianaki, Aikaterini, Adams, Sally, Alford, Chris, Arnoldy, Lizanne, Ayre, Elisabeth, Balikji, Stephanie, Benson, Sarah, Bruce, Gillian, Devenney, Lydia E, Frone, Michael R, Gunn, Craig, Heffernan, Thomas, Hensel, Kai O, Hogewoning, Anna, Johnson, Sean J, van Lawick van Pabst, Albertine E, van de Loo, Aurora J A E, Mackus, Marlou, Merlo, Agnese, Murphy, René J L, Owen, Lauren, Palmer, Emily O C, van Rossum, Charmaine J I, Scholey, Andrew, Terpstra, Chantal, Vatsalya, Vatsalya, Vermeulen, Sterre A, van Wijk, Michelle, Stock, Ann-Kathrin, Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Afd Pharmacology, Afd Pharmacoepi & Clinical Pharmacology, dIRAS RA-1, and IRAS OH Toxicology

Subjects
hangover, subjective intoxication, alcohol, sensitivity, blood alcohol concentration
Abstract

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their "normal" drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their "regular" drinking level, considerably higher alcohol intake-irrespective of the absolute amount-may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.

Published
2020

32. Proceedings of the 10th Alcohol Hangover Research Group Meeting in Utrecht, The Netherlands

Author

Afd Pharmacology, dIRAS RA-1, Pharmacology, Merlo, Agnese, Abbott, Zack, Alford, Chris, Balikji, Stephanie, Bruce, Gillian, Gunn, Craig, Iversen, Jacqueline, Iversen, Jim, Johnson, Sean J, Kruisselbrink, D., van de Loo, A.J.A.E., Mackus, M., Terpstra, C.G., Stock, Ann-Katrin, Verster, J.C., Afd Pharmacology, dIRAS RA-1, Pharmacology, Merlo, Agnese, Abbott, Zack, Alford, Chris, Balikji, Stephanie, Bruce, Gillian, Gunn, Craig, Iversen, Jacqueline, Iversen, Jim, Johnson, Sean J, Kruisselbrink, D., van de Loo, A.J.A.E., Mackus, M., Terpstra, C.G., Stock, Ann-Katrin, and Verster, J.C.

Published
2020

33. Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover

Author

Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Afd Pharmacology, Afd Pharmacoepi & Clinical Pharmacology, dIRAS RA-1, IRAS OH Toxicology, Verster, Joris C, Kruisselbrink, L Darren, Slot, Karin A, Anogeianaki, Aikaterini, Adams, Sally, Alford, Chris, Arnoldy, Lizanne, Ayre, Elisabeth, Balikji, Stephanie, Benson, Sarah, Bruce, Gillian, Devenney, Lydia E, Frone, Michael R, Gunn, Craig, Heffernan, Thomas, Hensel, Kai O, Hogewoning, Anna, Johnson, Sean J, van Lawick van Pabst, Albertine E, van de Loo, Aurora J A E, Mackus, Marlou, Merlo, Agnese, Murphy, René J L, Owen, Lauren, Palmer, Emily O C, van Rossum, Charmaine J I, Scholey, Andrew, Terpstra, Chantal, Vatsalya, Vatsalya, Vermeulen, Sterre A, van Wijk, Michelle, Stock, Ann-Kathrin, Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Afd Pharmacology, Afd Pharmacoepi & Clinical Pharmacology, dIRAS RA-1, IRAS OH Toxicology, Verster, Joris C, Kruisselbrink, L Darren, Slot, Karin A, Anogeianaki, Aikaterini, Adams, Sally, Alford, Chris, Arnoldy, Lizanne, Ayre, Elisabeth, Balikji, Stephanie, Benson, Sarah, Bruce, Gillian, Devenney, Lydia E, Frone, Michael R, Gunn, Craig, Heffernan, Thomas, Hensel, Kai O, Hogewoning, Anna, Johnson, Sean J, van Lawick van Pabst, Albertine E, van de Loo, Aurora J A E, Mackus, Marlou, Merlo, Agnese, Murphy, René J L, Owen, Lauren, Palmer, Emily O C, van Rossum, Charmaine J I, Scholey, Andrew, Terpstra, Chantal, Vatsalya, Vatsalya, Vermeulen, Sterre A, van Wijk, Michelle, and Stock, Ann-Kathrin

Published
2020

34. Proceedings of the 10th Alcohol Hangover Research Group Meeting in Utrecht, The Netherlands

Author

Merlo, Agnese, primary, Abbott, Zack, additional, Alford, Chris, additional, Balikji, Stephanie, additional, Bruce, Gillian, additional, Gunn, Craig, additional, Iversen, Jacqueline, additional, Iversen, Jim, additional, Johnson, Sean J., additional, Kruisselbrink, L. Darren, additional, Loo, Aurora J. A. E. van de, additional, Mackus, Marlou, additional, Terpstra, Chantal, additional, Stock, Ann-Kathrin, additional, and Verster, Joris C., additional

Published
2020
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36. Proceeding of the 9th Alcohol Hangover Research Group Meeting

Author

Merlo, Agnese, primary, Adams, Sally, additional, Benson, Sarah, additional, Devenney, Lydia, additional, Gunn, Craig, additional, Iversen, Jacqueline, additional, Johnson, Sean J., additional, Mackus, Marlou, additional, Scholey, Andrew, additional, Stock, Ann-Katrin, additional, van de Loo, Aurora J.A.E., additional, van Schrojenstein Lantman, Marith, additional, Wilod Versprille, Livia J.F., additional, and Verster, Joris C., additional

Published
2018
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37. Proceeding of the 9th alcohol hangover research group meeting

Author

Afd Pharmacology, LS IRAS Tox Algemeen, Pharmacology, Merlo, Agnese, Adams, Sally, Benson, Sarah, Devenney, Lydia, Gunn, Craig, Iversen, Jacqueline, Johnson, Sean J., Mackus, Marlou, Scholey, Andrew, Stock, Ann Katrin, van de Loo, Aurora J.A.E., Lantman, Marith van Schrojenstein, Versprille, Livia J.F.Wilod, Verster, Joris C., Afd Pharmacology, LS IRAS Tox Algemeen, Pharmacology, Merlo, Agnese, Adams, Sally, Benson, Sarah, Devenney, Lydia, Gunn, Craig, Iversen, Jacqueline, Johnson, Sean J., Mackus, Marlou, Scholey, Andrew, Stock, Ann Katrin, van de Loo, Aurora J.A.E., Lantman, Marith van Schrojenstein, Versprille, Livia J.F.Wilod, and Verster, Joris C.

Published
2017

38. Proceeding of the 9th Alcohol Hangover Research Group Meeting

Author

Merlo, Agnese, Adams, Sally, Benson, Sarah, Devenney, Lydia, Gunn, Craig, Iversen, Jacqueline, Johnson, Sean J., Mackus, Marlou, Scholey, Andrew, Stock, Ann-Katrin, van de Loo, Aurora J.A.E., van Schrojenstein Lantman, Marith, Wilod Versprille, Livia J.F., and Verster, Joris C.

Abstract

Background: Alcohol hangover is a common occurrence among individuals who have experienced an episode of heavy alcohol consumption the previous night. Until now defined as the general feeling of misery that develops once the Blood Alcohol Concentration approaches zero. Despite its prevalence and several related adverse consequences, insufficient research has been conducted with regards to this matter and further understanding of the pathology of alcohol hangover is necessary. During the 9th Alcohol Hangover Research Group meeting, held on April 29th 2017, Utrecht, The Netherlands, numerous aspects of alcohol hangover were presented and many advances with regards to determinants, biological and cognitive consequences and potential treatment have been presented. Conclusion: Precisely, a definition of alcohol hangover has been established and wider understandings of biological and cognitive effects, alcohol metabolism, immune functioning and potential treatment of alcohol hangover were presented and discussed. Further research and development are necessary to attain a wider understanding of the pathology of alcohol hangover.

Published
2017

39. Proceedings of the First Irish Alcohol Hangover Research Seminar

Author

Devenney, Lydia E., Stock, Ann-Kathrin, Merlo, Agnese, Hendriksen, Pauline A., Gunn, Craig A., Opitz, Antje, Bruce, Gillian, Verster, Joris C., Devenney, Lydia E., Stock, Ann-Kathrin, Merlo, Agnese, Hendriksen, Pauline A., Gunn, Craig A., Opitz, Antje, Bruce, Gillian, and Verster, Joris C.

40. Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover

Author

Verster, Joris C., Kruisselbrink, L. Darren, Slot, Karin A., Anogeianaki, Aikaterini, Adams, Sally, Alford, Chris, Arnoldy, Lizanne, Ayre, Elisabeth, Balikji, Stephanie, Benson, Sarah, Bruce, Gillian, Devenney, Lydia E., Frone, Michael R., Gunn, Craig, Heffernan, Thomas, Hensel, Kai O., Hogewoning, Anna, Johnson, Sean J., van Lawick van Pabst, Albertine E., van de Loo, Aurora J.A.E., Mackus, Marlou, Merlo, Agnese, Murphy, René J.L., Owen, Lauren, Palmer, Emily O.C., van Rossum, Charmaine J.I., Scholey, Andrew, Terpstra, Chantal, Vatsalya, Vatsalya, Vermeulen, Sterre A., van Wijk, Michelle, Stock, Ann-Kathrin, Verster, Joris C., Kruisselbrink, L. Darren, Slot, Karin A., Anogeianaki, Aikaterini, Adams, Sally, Alford, Chris, Arnoldy, Lizanne, Ayre, Elisabeth, Balikji, Stephanie, Benson, Sarah, Bruce, Gillian, Devenney, Lydia E., Frone, Michael R., Gunn, Craig, Heffernan, Thomas, Hensel, Kai O., Hogewoning, Anna, Johnson, Sean J., van Lawick van Pabst, Albertine E., van de Loo, Aurora J.A.E., Mackus, Marlou, Merlo, Agnese, Murphy, René J.L., Owen, Lauren, Palmer, Emily O.C., van Rossum, Charmaine J.I., Scholey, Andrew, Terpstra, Chantal, Vatsalya, Vatsalya, Vermeulen, Sterre A., van Wijk, Michelle, and Stock, Ann-Kathrin

Abstract

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their “normal” drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their “regular” drinking level, considerably higher alcohol intake—irrespective of the absolute amount—may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.

41. Alcohol Consumption Patterns during COVID-19 Lockdown and Their Relationship with Perceived Immune Fitness and Reported COVID-19 Symptoms.

Author

Merlo A, Hendriksen PA, Severeijns NR, Garssen J, Bruce G, and Verster JC

Abstract

Since the outbreak of the 2019 coronavirus (COVID-19) pandemic, lockdown periods have been installed to counteract the spread of the virus. These lockdowns, characterized by social isolation, have been associated with mood changes and increased stress. Individuals have used various strategies to cope with the negative effects of being in lockdown, including increasing the frequency and quantity of alcohol consumption. The aim of this study was to investigate mood before and during lockdown of individuals who reported consuming more, less, or the same amount of alcohol during lockdown, and examine how this impacts and perceived immune fitness and the presence and severity of COVID-19 symptoms. Analysis included a sub-sample from the 'Corona Lockdown: how fit are you?' (CLOFIT) study, comprising N = 761 participants who reported consuming alcohol in 2020. The results of the online survey showed that half of the participants did not alter their weekly alcohol consumption during lockdown (50.4%), whereas 25.9% of drinkers reported a reduction and 23.8% reported an increase in weekly alcohol consumption. Compared to individuals that did not alter their drinking behaviour, both increased and reduced alcohol consumption during lockdown was associated with poorer mood and higher stress levels. Increased alcohol consumption was associated with significantly reduced perceived immune fitness and a high presence and severity of COVID-19 symptoms. This effect was not significant among individuals with reduced or unaltered alcohol consumption.

Published
2021
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42. Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover.

Author

Verster JC, Kruisselbrink LD, Slot KA, Anogeianaki A, Adams S, Alford C, Arnoldy L, Ayre E, Balikji S, Benson S, Bruce G, Devenney LE, Frone MR, Gunn C, Heffernan T, Hensel KO, Hogewoning A, Johnson SJ, van Lawick van Pabst AE, van de Loo AJAE, Mackus M, Merlo A, Murphy RJL, Owen L, Palmer EOC, van Rossum CJI, Scholey A, Terpstra C, Vatsalya V, Vermeulen SA, van Wijk M, and Stock AK

Abstract

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their "normal" drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their "regular" drinking level, considerably higher alcohol intake-irrespective of the absolute amount-may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.

Published
2020
Full Text
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