Search

Your search keyword '"Meucci, Gianmichele"' showing total 190 results
Start Over Author "Meucci, Gianmichele"
190 results on '"Meucci, Gianmichele"'

1. Use of biologics for the management of Crohn's disease: IG-IBD clinical guidelines based on the GRADE methodology

Author

Bertani, Lorenzo, Bezzio, Cristina, Bodini, Giorgia, Bossa, Fabrizio, Buda, Andrea, Calabrese, Emma, Furfaro, Federica, Leone, Salvatore, Mocciaro, Filippo, Onali, Sara, Pastorelli, Luca, Previtali, Enrica, Principi, Mariabeatrice, Renna, Sara, Ribaldone, Davide Giuseppe, Rispo, Antonio, Rizzello, Fernando, Saibeni, Simone, Sampietro, Gianluca Matteo, Savarino, Edoardo, Testa, Anna, Variola, Angela, Viscido, Angelo, Ardizzone, Sandro, Biancone, Livia, Cappello, Maria, Castiglione, Fabiana, Ciccocioppo, Rachele, Comberlato, Michele, Costa, Francesco, D'Incà, Renata, Danese, Silvio, Di Sabatino, Antonio, Fries, Walter, Gionchetti, Paolo, Latella, Giovanni, Manguso, Francesco, Mastronardi, Mauro, Meucci, Gianmichele, Milla, Monica, Scribano, Maria Lia, Vecchi, Maurizio, Macaluso, Fabio Salvatore, Papi, Claudio, Orlando, Ambrogio, Festa, Stefano, Pugliese, Daniela, Bonovas, Stefanos, Pansieri, Claudia, Piovani, Daniele, Fiorino, Gionata, Fantini, Massimo Claudio, Caprioli, Flavio, Daperno, Marco, and Armuzzi, Alessandro

Published
2023
Full Text
View/download PDF

2. Use of biologics and small molecule drugs for the management of moderate to severe ulcerative colitis: IG-IBD clinical guidelines based on the GRADE methodology

Author

Bertani, Lorenzo, Bezzio, Cristina, Bodini, Giorgia, Bossa, Fabrizio, Buda, Andrea, Calabrese, Emma, Furfaro, Federica, Leone, Salvatore, Mocciaro, Filippo, Onali, Sara, Pastorelli, Luca, Previtali, Enrica, Principi, Mariabeatrice, Renna, Sara, Ribaldone, Davide Giuseppe, Rispo, Antonio, Rizzello, Fernando, Saibeni, Simone, Sampietro, Gianluca Matteo, Savarino, Edoardo, Testa, Anna, Variola, Angela, Viscido, Angelo, Ardizzone, Sandro, Biancone, Livia, Cappello, Maria, Castiglione, Fabiana, Ciccocioppo, Rachele, Comberlato, Michele, Costa, Francesco, D'Incà, Renata, Danese, Silvio, Di Sabatino, Antonio, Fries, Walter, Gionchetti, Paolo, Latella, Giovanni, Manguso, Francesco, Mastronardi, Mauro, Meucci, Gianmichele, Milla, Monica, Scribano, Maria Lia, Vecchi, Maurizio, Macaluso, Fabio Salvatore, Orlando, Ambrogio, Papi, Claudio, Festa, Stefano, Pugliese, Daniela, Bonovas, Stefanos, Pansieri, Claudia, Piovani, Daniele, Fiorino, Gionata, Fantini, Massimo Claudio, Caprioli, Flavio, Daperno, Marco, and Armuzzi, Alessandro

Published
2022
Full Text
View/download PDF

3. Complications and early mortality in percutaneous endoscopic gastrostomy placement in lombardy: A multicenter prospective cohort study

Author

Anderloni, Andrea, Di Leo, Milena, Barzaghi, Franco, Semeraro, Rossella, Meucci, Gianmichele, Marino, Roberta, Amato, Loretta, Frigerio, Mauro, Saladino, Valeria, Toldi, Anna, Manfredi, Guido, Redaelli, Alessandro, Feliziani, Marcella, De Roberto, Giuseppe, Boni, Francesca, Scacchi, Gianlorenzo, Mosca, Davide, Devani, Massimo, Arena, Monica, Massidda, Marco, Zanoni, Paolo, Ciscato, Camilla, Casini, Valentina, Beretta, Paolo, Forti, Edoardo, Salerno, Raffaele, Caramia, Vitantonio, Bianchetti, Mario, Tomba, Carolina, Evangelista, Andrea, Repici, Alessandro, Soncini, Marco, Maconi, Giovanni, Manes, Gianpiero, and Gullotta, Renzo

Published
2019
Full Text
View/download PDF

4. Use of biosimilars in inflammatory bowel disease: a position update of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD)

Author

Leone, Salvatore, Previtali, Enrica, Aloi, Marina, Alvisi, Patrizia, Antonelli, Elisabetta, Ardizzone, Sandro, Astegiano, Marco, Baldoni, Monia, Beltrami, Marina, Biancone, Livia, Bodini, Giorgia, Buda, Andrea, Bossa, Fabrizio, Bracci, Fiammetta, Calabrese, Emma, Cappello, Maria, Castiglione, Fabiana, Ciacci, Carolina, Cicala, Michele, Ciccocioppo, Rachele, Comberlato, Michele, Cortelezzi, Claudio Camillo, Cosintino, Rocco, Costa, Francesco, Costantino, Giuseppe, Cucchiara, Salvatore, Cuomo, Antonio, D’Incà, Renata, Di Paolo, Maria Carla, Di Sabatino, Antonio, Di Sario, Antonio, Frieri, Giuseppe, Fries, Walter, Gasbarrini, Antonio, Geccherle, Andrea, Gionchetti, Paolo, Graziani, Maria Giovanna, Grossi, Laurino, Guidi, Luisa, Imperiali, Gianni, Latella, Giovanni, Lionetti, Paolo, Inserra, Gaetano, Maconi, Giovanni, Manguso, Francesco, Marino, Marco, Mastronardi, Mauro, Mazzuoli, Silvia, Meucci, Gianmichele, Mendolaro, Marco, Milla, Monica, Mocci, Giammarco, Monteleone, Giovanni, Bortoluzzi, Francesco Neri, Pagnini, Cristiano, Pastorelli, Luca, Pica, Roberta, Piergallini, Simona, Privitera, Antonello, Renna, Sara, Ribaldone, Davide Giuseppe, Ricci, Chiara, Rispo, Antonio, Rocca, Rodolfo, Romano, Claudio, Romano, Marco, Russo, Giovanni, Sablich, Renato, Saibeni, Simone, Savarino, Edoardo, Scribano, Maria Lia, Spagnuolo, Rocco, Stasi, Elisa, Terpin, Maria Maddalena, Testa, Anna, Valpiani, Daniela, Variola, Angela, Vernia, Piero, Vitale, Giovanna, Zoli, Giorgio, Fiorino, Gionata, Caprioli, Flavio, Daperno, Marco, Mocciaro, Filippo, Principi, Mariabeatrice, Viscido, Angelo, Fantini, Massimo Claudio, Orlando, Ambrogio, Papi, Claudio, Annese, Vito, Danese, Silvio, Vecchi, Maurizio, Rizzello, Fernando, and Armuzzi, Alessandro

Published
2019
Full Text
View/download PDF

5. Prevalence of Disease-Related Malnutrition and Micronutrients Deficit in Patients with Inflammatory Bowel Disease: A Multicentric Cross-Sectional Study by the GSMII (Inflammatory Bowel Disease Study Group).

Author

Viganò, Chiara, Palermo, Andrea, Mulinacci, Giacomo, Pirola, Lorena, Losco, Alessandra, Meucci, Gianmichele, Saibeni, Simone, Pastorelli, Luca, Amato, Arnaldo, Gatti, Mario, Cortelezzi, Claudio, Sabatino, Antonio Di, Morganti, Daniela, Boni, Francesca, Grasso, Gianalberto, Casella, Giovanni, Casini, Valentina, Caprioli, Flavio Andrea, Vecchi, Maurizio, and Bezzio, Cristina

Published
2024
Full Text
View/download PDF

6. Prevalence of Disease-Related Malnutrition and Micronutrients Deficit in Patients with Inflammatory Bowel Disease: A Multicentric Cross-Sectional Study by the GSMII (Inflammatory Bowel Disease Study Group)

Author

Viganò, Chiara, primary, Palermo, Andrea, additional, Mulinacci, Giacomo, additional, Pirola, Lorena, additional, Losco, Alessandra, additional, Meucci, Gianmichele, additional, Saibeni, Simone, additional, Pastorelli, Luca, additional, Amato, Arnaldo, additional, Gatti, Mario, additional, Cortelezzi, Claudio, additional, Di Sabatino, Antonio, additional, Morganti, Daniela, additional, Boni, Francesca, additional, Grasso, Gianalberto, additional, Casella, Giovanni, additional, Casini, Valentina, additional, Caprioli, Flavio Andrea, additional, Vecchi, Maurizio, additional, Bezzio, Cristina, additional, Bergna, Irene, additional, Radaelli, Franco, additional, Mengoli, Caterina, additional, and Massironi, Sara, additional

Published
2023
Full Text
View/download PDF

8. Safety of treatments for inflammatory bowel disease: Clinical practice guidelines of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD)

Author

Aratari, Annalisa, Bossa, Fabrizio, Cappello, Maria, Cassinotti, Andrea, Chiriatti, Alberto, Fiorino, Gionata, Formica, Vincenzo, Guidi, Luisa, Losco, Alessandra, Mocciaro, Filippo, Onali, Sara, Pastorelli, Luca, Pica, Roberta, Principi, Mariabeatrice, Renna, Sara, Ricci, Chiara, Rispo, Antonio, Rogai, Francesca, Sarmati, Loredana, Scaldaferri, Franco, Spina, Luisa, Tambasco, Rosy, Testa, Anna, Viscido, Angelo, Biancone, Livia, Annese, Vito, Ardizzone, Sandro, Armuzzi, Alessandro, Calabrese, Emma, Caprioli, Flavio, Castiglione, Fabiana, Comberlato, Michele, Cottone, Mario, Danese, Silvio, Daperno, Marco, D’Incà, Renata, Frieri, Giuseppe, Fries, Walter, Gionchetti, Paolo, Kohn, Anna, Latella, Giovanni, Milla, Monica, Orlando, Ambrogio, Papi, Claudio, Petruzziello, Carmelina, Riegler, Gabriele, Rizzello, Fernando, Saibeni, Simone, Scribano, Maria Lia, Vecchi, Maurizio, Vernia, Piero, and Meucci, Gianmichele

Published
2017
Full Text
View/download PDF

9. The PROSIT Cohort of Infliximab Biosimilar in IBD: A Prolonged Follow-up on the Effectiveness and Safety Across Italy

Author

Armuzzi, Alessandro, Fiorino, Gionata, Variola, Angela, Manetti, Natalia, Fries, Walter, Orlando, Ambrogio, Maconi, Giovanni, Bossa, Fabrizio, Cappello, Maria, Biancone, Livia, Cantoro, Laura, Costa, Francesco, D’Incà, Renata, Lionetti, Paolo, Principi, Mariabeatrice, Castiglione, Fabiana, Annunziata, Maria L, Di Sabatino, Antonio, Di Girolamo, Maria, Terpin, Maria M, Cortelezzi, Claudio C, Saibeni, Simone, Amato, Arnaldo, Ardizzone, Sandro, Guidi, Luisa, Danese, Silvio, Massella, Arianna, Ventra, Agostino, Rizzuto, Giulia, Massari, Alessandro, Perri, Francesco, Annese, Vito, Saettone, Silvia, Tari, Roberto, Petruzzellis, Carlo, Meucci, Gianmichele, Imperiali, Gianni, Guglielmi, Francesco W, Mazzuoli, Silvia, Caserta, Luigi, Caterina Parodi, Maria, Colli, Agostino, Ronchetti, Anna, Pugliese, Daniela, Geccherle, Andrea, Rogai, Francesca, Milani, Stefano, Renna, Sara, Cassinotti, Andrea, Andriulli, Angelo, Martino, Giuseppina, Scrivo, Barbara, Troncone, Edoardo, Kohn, Anna, Bertani, Lorenzo, Lorenzon, Greta, Ghione, Silvia, Nardone, Olga, Vecchi, Maurizio, Bertani, Angela, Bosani, Matteo A, Bezzio, Cristina, and Salerno, Raffaele

Published
2019
Full Text
View/download PDF

10. Use of biologics for the management of Crohn's disease: IG-IBD clinical guidelines based on the GRADE methodology

Author

Macaluso, Fabio Salvatore, primary, Papi, Claudio, additional, Orlando, Ambrogio, additional, Festa, Stefano, additional, Pugliese, Daniela, additional, Bonovas, Stefanos, additional, Pansieri, Claudia, additional, Piovani, Daniele, additional, Fiorino, Gionata, additional, Fantini, Massimo Claudio, additional, Caprioli, Flavio, additional, Daperno, Marco, additional, Armuzzi, Alessandro, additional, Bertani, Lorenzo, additional, Bezzio, Cristina, additional, Bodini, Giorgia, additional, Bossa, Fabrizio, additional, Buda, Andrea, additional, Calabrese, Emma, additional, Furfaro, Federica, additional, Leone, Salvatore, additional, Mocciaro, Filippo, additional, Onali, Sara, additional, Pastorelli, Luca, additional, Previtali, Enrica, additional, Principi, Mariabeatrice, additional, Renna, Sara, additional, Ribaldone, Davide Giuseppe, additional, Rispo, Antonio, additional, Rizzello, Fernando, additional, Saibeni, Simone, additional, Sampietro, Gianluca Matteo, additional, Savarino, Edoardo, additional, Testa, Anna, additional, Variola, Angela, additional, Viscido, Angelo, additional, Ardizzone, Sandro, additional, Biancone, Livia, additional, Cappello, Maria, additional, Castiglione, Fabiana, additional, Ciccocioppo, Rachele, additional, Comberlato, Michele, additional, Costa, Francesco, additional, D'Incà, Renata, additional, Danese, Silvio, additional, Di Sabatino, Antonio, additional, Fries, Walter, additional, Gionchetti, Paolo, additional, Latella, Giovanni, additional, Manguso, Francesco, additional, Mastronardi, Mauro, additional, Meucci, Gianmichele, additional, Milla, Monica, additional, Scribano, Maria Lia, additional, and Vecchi, Maurizio, additional

Published
2023
Full Text
View/download PDF

11. Infliximab three-dose induction regimen in severe corticosteroid-refractory ulcerative colitis: Early and late outcome and predictors of colectomy

Author

Monterubbianesi, Rita, Aratari, Annalisa, Armuzzi, Alessandro, Daperno, Marco, Biancone, Livia, Cappello, Maria, Annese, Vito, Riegler, Gabriele, Orlando, Ambrogio, Viscido, Angelo, Meucci, Gianmichele, Gasbarrini, Antonio, Guidi, Luisa, Lavagna, Alessandro, Sostegni, Raffaello, Onali, Sara, Papi, Claudio, and Kohn, Anna

Published
2014
Full Text
View/download PDF

15. Use of biologics and small molecule drugs for the management of moderate to severe ulcerative colitis: IG-IBD clinical guidelines based on the GRADE methodology

Author

Macaluso, Fabio Salvatore, primary, Orlando, Ambrogio, additional, Papi, Claudio, additional, Festa, Stefano, additional, Pugliese, Daniela, additional, Bonovas, Stefanos, additional, Pansieri, Claudia, additional, Piovani, Daniele, additional, Fiorino, Gionata, additional, Fantini, Massimo Claudio, additional, Caprioli, Flavio, additional, Daperno, Marco, additional, Armuzzi, Alessandro, additional, Bertani, Lorenzo, additional, Bezzio, Cristina, additional, Bodini, Giorgia, additional, Bossa, Fabrizio, additional, Buda, Andrea, additional, Calabrese, Emma, additional, Furfaro, Federica, additional, Leone, Salvatore, additional, Mocciaro, Filippo, additional, Onali, Sara, additional, Pastorelli, Luca, additional, Previtali, Enrica, additional, Principi, Mariabeatrice, additional, Renna, Sara, additional, Ribaldone, Davide Giuseppe, additional, Rispo, Antonio, additional, Rizzello, Fernando, additional, Saibeni, Simone, additional, Sampietro, Gianluca Matteo, additional, Savarino, Edoardo, additional, Testa, Anna, additional, Variola, Angela, additional, Viscido, Angelo, additional, Ardizzone, Sandro, additional, Biancone, Livia, additional, Cappello, Maria, additional, Castiglione, Fabiana, additional, Ciccocioppo, Rachele, additional, Comberlato, Michele, additional, Costa, Francesco, additional, D'Incà, Renata, additional, Danese, Silvio, additional, Di Sabatino, Antonio, additional, Fries, Walter, additional, Gionchetti, Paolo, additional, Latella, Giovanni, additional, Manguso, Francesco, additional, Mastronardi, Mauro, additional, Meucci, Gianmichele, additional, Milla, Monica, additional, Scribano, Maria Lia, additional, and Vecchi, Maurizio, additional

Published
2022
Full Text
View/download PDF

26. Use of biosimilars in inflammatory bowel disease: a position update of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD)

Author

Fiorino, Gionata, primary, Caprioli, Flavio, additional, Daperno, Marco, additional, Mocciaro, Filippo, additional, Principi, Mariabeatrice, additional, Viscido, Angelo, additional, Fantini, Massimo Claudio, additional, Orlando, Ambrogio, additional, Papi, Claudio, additional, Annese, Vito, additional, Danese, Silvio, additional, Vecchi, Maurizio, additional, Rizzello, Fernando, additional, Armuzzi, Alessandro, additional, Leone, Salvatore, additional, Previtali, Enrica, additional, Aloi, Marina, additional, Alvisi, Patrizia, additional, Antonelli, Elisabetta, additional, Ardizzone, Sandro, additional, Astegiano, Marco, additional, Baldoni, Monia, additional, Beltrami, Marina, additional, Biancone, Livia, additional, Bodini, Giorgia, additional, Buda, Andrea, additional, Bossa, Fabrizio, additional, Bracci, Fiammetta, additional, Calabrese, Emma, additional, Cappello, Maria, additional, Castiglione, Fabiana, additional, Ciacci, Carolina, additional, Cicala, Michele, additional, Ciccocioppo, Rachele, additional, Comberlato, Michele, additional, Cortelezzi, Claudio Camillo, additional, Cosintino, Rocco, additional, Costa, Francesco, additional, Costantino, Giuseppe, additional, Cucchiara, Salvatore, additional, Cuomo, Antonio, additional, D’Incà, Renata, additional, Di Paolo, Maria Carla, additional, Di Sabatino, Antonio, additional, Di Sario, Antonio, additional, Frieri, Giuseppe, additional, Fries, Walter, additional, Gasbarrini, Antonio, additional, Geccherle, Andrea, additional, Gionchetti, Paolo, additional, Graziani, Maria Giovanna, additional, Grossi, Laurino, additional, Guidi, Luisa, additional, Imperiali, Gianni, additional, Latella, Giovanni, additional, Lionetti, Paolo, additional, Inserra, Gaetano, additional, Maconi, Giovanni, additional, Manguso, Francesco, additional, Marino, Marco, additional, Mastronardi, Mauro, additional, Mazzuoli, Silvia, additional, Meucci, Gianmichele, additional, Mendolaro, Marco, additional, Milla, Monica, additional, Mocci, Giammarco, additional, Monteleone, Giovanni, additional, Bortoluzzi, Francesco Neri, additional, Pagnini, Cristiano, additional, Pastorelli, Luca, additional, Pica, Roberta, additional, Piergallini, Simona, additional, Privitera, Antonello, additional, Renna, Sara, additional, Ribaldone, Davide Giuseppe, additional, Ricci, Chiara, additional, Rispo, Antonio, additional, Rocca, Rodolfo, additional, Romano, Claudio, additional, Romano, Marco, additional, Russo, Giovanni, additional, Sablich, Renato, additional, Saibeni, Simone, additional, Savarino, Edoardo, additional, Scribano, Maria Lia, additional, Spagnuolo, Rocco, additional, Stasi, Elisa, additional, Terpin, Maria Maddalena, additional, Testa, Anna, additional, Valpiani, Daniela, additional, Variola, Angela, additional, Vernia, Piero, additional, Vitale, Giovanna, additional, and Zoli, Giorgio, additional

Published
2019
Full Text
View/download PDF

34. Cancer Risk in Inflammatory Bowel Disease: A 6-Year Prospective Multicenter Nested Case–Control IG-IBD Study.

Author

Biancone, Livia, Armuzzi, Alessandro, Scribano, Maria Lia, Castiglione, Fabiana, D'Incà, Renata, Orlando, Ambrogio, Papi, Claudio, Daperno, Marco, Vecchi, Maurizio, Riegler, Gabriele, Fries, Walter, Alvisi, Patrizia, Meucci, Gianmichele, Mocciaro, Filippo, Rogai, Francesca, Festa, Stefano, Guidi, Luisa, Testa, Anna, Spina, Luisa, and Renna, Sara

Published
2020
Full Text
View/download PDF

35. The PROSIT-BIO Cohort: A Prospective Observational Study of Patients with Inflammatory Bowel Disease Treated with Infliximab Biosimilar

Author

Fiorino, Gionata, Manetti, Natalia, Armuzzi, Alessandro, Orlando, Ambrogio, Variola, Angela, Bonovas, Stefanos, Bossa, Fabrizio, Maconi, Giovanni, D'Incà, Renata, Lionetti, Paolo, Cantoro, Laura, Fries, Walter, Annunziata, Maria L., Costa, Francesco, Terpin, Maria M., Biancone, Livia, Cortelezzi, Claudio C., Amato, Arnaldo, Ardizzone, Sandro, Danese, Silvio, Guidi, Luisa, Rizzuto, Giulia, Massella, Arianna, Andriulli, Angelo, Massari, Alessandro, Lorenzon, Greta, Ghione, Silvia, Kohn, Anna, Ventra, Agostino, Annese, Vito, Principi, Mariabeatrice, Di Girolamo, Maria, Bertani, Angela, Saettone, Silvia, Tari, Roberto, Petruzzellis, Carlo, Guglielmi, Francesco W., Mazzuoli, Silvia, Cappello, Maria, Viola, Anna, Castiglione, Fabiana, Nardone, Olga, Di Sabatino, Antonio, Saibeni, Simone, Bezzio, Cristina, Caserta, Luigi, Parodi, Maria Caterina, Meucci, Gianmichele, Colli, Agostino, Ronchetti, Anna, Vecchi, Maurizio, Bertani, Lorenzo, Bosani, Matteo A., Tronconi, Edoardo, Imperiali, Gianni, Salerno, Raffaele, Rogai, Francesca, Milani, Stefano, Pugliese, Daniela, Renna, Sara, Geccherle, Andrea, Martino, Giuseppina, Cassinotti, Andrea, Fiorino, G, Manetti, N, Armuzzi, A, Orlando, A, Variola, A, Bonovas, S, Bossa, F, Maconi, G, D'Inca, R, Lionetti, P, Cantoro, L, Fries, W, Annunziata, Ml, Costa, F, Terpin, Mm, Biancone, L, Cortelezzi, Cc, Amato, A, Ardizzone, S, Danese, S, Guidi, L, Rizzuto, G, Massella, A, Andriulli, A, Massari, A, Lorenzon, G, Ghione, S, Kohn, A, Ventra, A, and Annese, V

Subjects
Male, Databases, Factual, Ulcerative, Rate ratio, Inflammatory bowel disease, 0302 clinical medicine, Crohn Disease, Monoclonal, Immunology and Allergy, Prospective Studies, Remsima, Prospective cohort study, Infusions, Intravenous, biosimilar, Crohn's disease, CT-P13, inflammatory bowel disease, Inflectra, Infliximab, ulcerative colitis, Gastroenterology, Adolescent, Adult, Antibodies, Monoclonal, Biosimilar Pharmaceuticals, Colitis, Ulcerative, Female, Gastrointestinal Agents, Humans, Treatment Outcome, Young Adult, Colitis, Ulcerative colitis, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Intravenous, Cohort study, medicine.drug, medicine.medical_specialty, Infusions, Crohn's disease, ulcerative colitis, inflammatory bowel disease, Infliximab, Remsima, Inflectra, biosimilar, CT-P13, Antibodies, 03 medical and health sciences, Databases, Internal medicine, medicine, Adverse effect, Factual, business.industry, Settore MED/09 - MEDICINA INTERNA, medicine.disease, business
Abstract

Background: Few data are available on the safety and efficacy of infliximab biosimilar CT-P13 in patients with ulcerative colitis and Crohn's disease. Methods: A prospective, multicenter, cohort study using a structured database. Results: Consecutive patients (313 Crohn's disease and 234 ulcerative colitis) were enrolled from 31 referral centers 311 patients were naive to anti-tumor necrosis factor alpha, 139 had a previous exposure to biologics, and the remaining 97 were switched to CT-P13 after a mean of 18 6 14 infusions of infliximab. The mean follow-up was 4.3 6 +/- 2.8 months, and the total follow-up time was 195 patient-years. After 2061 infusions, 66 serious adverse events were reported (12.1%), 38 (6.9%) of them were infusion-related reactions. The biosimilar had to be stopped in 29 (5.3%) cases for severe infusion reactions (8 naive, 19 previous exposed, and 2 switch), and in further 16 patients (2.9%) for other serious adverse events. Infusion reactions were significantly more frequent in patients pre-exposed to infliximab than to other anti-tumor necrosis factor alpha (incidence rate ratio = 2.82, 95% CI: 1.05-7.9). The efficacy of the biosimilar was evaluated in 434 patients who received treatment for at least 8 weeks, using time-to-event methods for censored observations: 35 patients were primary failures (8.1%). After further 8, 16, and 24 weeks, the efficacy estimations were 95.7%, 86.4%, and 73.7% for naive, 97.2%, 85.2%, and 62.2% for pre-exposed, and 94.5%, 90.8%, and 78.9% for switch, respectively (log-rank P = 0.64). Conclusions: Although no direct comparison was performed, preliminary data on efficacy and safety of CT-P13 were in line with those of infliximab.

Published
2017

37. Safety of treatments for inflammatory bowel disease: Clinical practice guidelines of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD)

Author

Biancone, Livia, primary, Annese, Vito, additional, Ardizzone, Sandro, additional, Armuzzi, Alessandro, additional, Calabrese, Emma, additional, Caprioli, Flavio, additional, Castiglione, Fabiana, additional, Comberlato, Michele, additional, Cottone, Mario, additional, Danese, Silvio, additional, Daperno, Marco, additional, D’Incà, Renata, additional, Frieri, Giuseppe, additional, Fries, Walter, additional, Gionchetti, Paolo, additional, Kohn, Anna, additional, Latella, Giovanni, additional, Milla, Monica, additional, Orlando, Ambrogio, additional, Papi, Claudio, additional, Petruzziello, Carmelina, additional, Riegler, Gabriele, additional, Rizzello, Fernando, additional, Saibeni, Simone, additional, Scribano, Maria Lia, additional, Vecchi, Maurizio, additional, Vernia, Piero, additional, Meucci, Gianmichele, additional, Aratari, Annalisa, additional, Bossa, Fabrizio, additional, Cappello, Maria, additional, Cassinotti, Andrea, additional, Chiriatti, Alberto, additional, Fiorino, Gionata, additional, Formica, Vincenzo, additional, Guidi, Luisa, additional, Losco, Alessandra, additional, Mocciaro, Filippo, additional, Onali, Sara, additional, Pastorelli, Luca, additional, Pica, Roberta, additional, Principi, Mariabeatrice, additional, Renna, Sara, additional, Ricci, Chiara, additional, Rispo, Antonio, additional, Rogai, Francesca, additional, Sarmati, Loredana, additional, Scaldaferri, Franco, additional, Spina, Luisa, additional, Tambasco, Rosy, additional, Testa, Anna, additional, and Viscido, Angelo, additional

Published
2017
Full Text
View/download PDF

40. 439 The PROSIT-BIO Cohort of the IG-IBD: A Prospective Observational Study of Patients With Inflammatory Bowel Disease Treated With Infliximab BioSimilars

Author

Fiorino, Gionata, primary, Manetti, Natalia, additional, Variola, Angela, additional, Bossa, Fabrizio, additional, Rizzuto, Giulia, additional, Armuzzi, Alessandro, additional, Massari, Alessandro, additional, Ghione, Silvia, additional, Cantoro, Laura, additional, Lorenzon, Greta, additional, Fries, Walter, additional, Annunziata, Maria Laura, additional, Costa, Francesco, additional, Terpin, Maria M., additional, Principi, Mariabeatrice, additional, Cortelezzi, Claudio C., additional, Biancone, Livia, additional, Amato, Arnaldo, additional, Occhipinti, Pietro, additional, Mazzuoli, Silvia, additional, Ardizzone, Sandro, additional, Girolamo, Maria Di, additional, Alvisi, Patrizia, additional, Meucci, Gianmichele, additional, Caserta, Luigi, additional, Saibeni, Simone, additional, Petruzzzellis, Carlo, additional, Ronchetti, Anna, additional, Cappello, Maria, additional, Castiglione, Fabiana, additional, Danese, Silvio, additional, Massella, Arianna, additional, Varvara, Doriana, additional, Orlando, Ambrogio, additional, and Annese, Vito, additional

Published
2016
Full Text
View/download PDF

41. Su1266 Characterization of Incident Cases of Cancer in Inflammatory Bowel Disease: A Prospective Multicenter Nested Case-Control IG-IBD Study

Author

Biancone, Livia, primary, Armuzzi, Alessandro, additional, Lia, Scribano Maria, additional, D'Inca, Renata, additional, Papi, Claudio, additional, Spina, Luisa, additional, Ruffa, Alessandra, additional, Petruzziello, Carmelina, additional, Guidi, Luisa, additional, Kohn, Anna, additional, Calabrese, Emma, additional, Mocciaro, Filippo, additional, Alvisi, Patrizia, additional, Angelucci, Erika, additional, Monterubbianesi, Rita, additional, Fries, Walter, additional, Riegler, Gabriele, additional, Castiglione, Fabiana, additional, Margagnoni, Giovanna, additional, Renna, Sara, additional, Di Mitri, Roberto, additional, Meucci, Gianmichele, additional, Rogai, Francesca, additional, Ardizzone, Sandro, additional, Rossi, Alessandra, additional, Orlando, Ambrogio, additional, and Pallone, Francesco, additional

Published
2015
Full Text
View/download PDF

42. Newly diagnosed neoplasia in a cohort of Crohn’s Disease patients treated with Infliximab: a 3 years longer follow up from a multicenter matched-pair study

Author

Biancone, Livia, Orlando, Ambrogio, Kohn, Anna, Ardizzone, Sandro, Daperno, Marco, Angelucci, Erika, Castiglione, Fabiana, Renata D'Incà, Papi, Claudio, Rizzello, Fernando, Meucci, Gianmichele, Riegler, Gabriele, Petruzziello, Carmelina, Mocciaro, Filippo, Onali, Sara, Calabrese, Emma, Cottone, Mario, and Pallone, Francesco

Subjects
Settore MED/12 - Gastroenterologia
Published
2009

43. Su1366 Characterization of Incident Cases of Cancer in Inflammatory Bowel Disease: A Prospective Multicenter Matched-Pair IG-IBD Study

Author

Biancone, Livia, primary, Petruzziello, Carmelina, additional, Armuzzi, Alessandro, additional, Scribano, Maria Lia, additional, Orlando, Ambrogio, additional, Castiglione, Fabiana, additional, Papi, Claudio, additional, D'Inca, Renata, additional, Calabrese, Emma, additional, Condino, Giovanna, additional, Onali, Sara, additional, Kohn, Anna, additional, Mocciaro, Filippo, additional, Frankovic, Iris, additional, Monterubbianesi, Rita, additional, Alvisi, Patrizia, additional, Fries, Walter, additional, Riegler, Gabriele, additional, Guidi, Luisa, additional, Margagnoni, Giovanna, additional, Meucci, Gianmichele, additional, Rogai, Francesca, additional, Spina, Luisa, additional, Ardizzone, Sandro, additional, and Pallone, Francesco, additional

Published
2014
Full Text
View/download PDF

44. Sa1232 Infliximab Three-Dose Induction Regimen in Severe Corticosteroid-Refractory Ulcerative Colitis: Early and Late Outcome and Predictors of Colectomy

Author

Monterubbianesi, Rita, primary, Aratari, Annalisa, additional, Armuzzi, Alessandro, additional, Daperno, Marco, additional, Biancone, Livia, additional, Cappello, Maria, additional, Annese, Vito, additional, Riegler, Gabriele, additional, Orlando, Ambrogio, additional, Viscido, Angelo, additional, Meucci, Gianmichele, additional, Gasbarrini, Antonio, additional, Guidi, Luisa, additional, Lavagna, Alessandro, additional, Sostegni, Raffaello, additional, Papi, Claudio, additional, and Kohn, Anna, additional

Published
2014
Full Text
View/download PDF

45. Tu1144 Could Infliximab Avoid Colectomy in Patients With Severe Ulcerative Colitis? A Multicentre Italian Experience

Author

Monterubbianesi, Rita, primary, Aratari, Annalisa, additional, Armuzzi, Alessandro, additional, Biancone, Livia, additional, Cappello, Maria, additional, Lavagna, Alessandro, additional, Annese, Vito, additional, Viscido, Angelo, additional, Riegler, Gabriele, additional, Meucci, Gianmichele, additional, Daperno, Marco, additional, Orlando, Ambrogio, additional, Guidi, Luisa, additional, Onali, Sara, additional, Gasbarrini, Antonio, additional, Sostegni, Raffaello, additional, Papi, Claudio, additional, and Kohn, Anna, additional

Published
2013
Full Text
View/download PDF

46. Mo1264 Clinical Characteristics of Inflammatory Bowel Disease May Influence the Cancer Risk When Using Immunomodulators: Incident Cases of Cancer in a Multicenter Case-Control Study

Author

Petrruzziello, Carmelina, primary, Armuzzi, Alessandro, additional, Kohn, Anna, additional, D'Incà, Renata, additional, Papi, Claudio, additional, Spina, Luisa, additional, Guidi, Luisa, additional, Scribano, Maria Lia, additional, Onali, Sara, additional, Condino, Giovanna, additional, Calabrese, Emma, additional, Monterubbianesi, Rita, additional, Alvisi, Patrizia, additional, Fries, Walter, additional, Riegler, Gabriele, additional, Castiglione, Fabiana, additional, Margagnoni, Giovanna, additional, Meucci, Gianmichele, additional, Rogai, Francesca, additional, Pallone, Francesco, additional, and Biancone, Livia, additional

Published
2013
Full Text
View/download PDF

47. The problem of adherence to therapy in ulcerative colitis and the potential utility of multi-matrix system (MMX) technology.

Author

Bezzio, Cristina, Fascì-Spurio, Federica, Viganò, Chiara, Meucci, Gianmichele, Papi, Claudio, and Saibeni, Simone

Subjects
COLITIS treatment, ULCERATIVE colitis, MESALAMINE, BUDESONIDE, DISEASE remission
Abstract

Introduction:Ulcerative colitis (uc) is a chronic condition and for the vast majority of patients, life-long treatment is required. low adherence to therapy is an emerging issue. since low adherence is associated with poor clinical outcomes and increased costs, it is becoming crucial to identify strategies in order to improve it. Areas covered:We performed literature searches in PubMed using the terms ‘adherence’, ‘mesalamine’, ‘budesonide MMX’, ‘MMX technology’ in combination with ‘ulcerative colitis’. Firstly, we present the key-concepts of therapy for UC and discuss the problem of the adherence and how to measure it. Then, we provide data on the extent of the problem and the causes and consequences from clinical and economic point of views. Finally, we focus on treatment-related variables associated with non-adherence and treatment-related strategies to improve adherence, paying particular attention to Multi Matrix system (MMX) technology applied to mesalazine and budesonide. Expert commentary:The pharmaceutical industry and scientific community are making efforts to simplify treatments for UC. MMX technology, which allows a reduction in the number of pills to be taken and daily administrations, may facilitate adherence to treatment and carry further clinical benefits. [ABSTRACT FROM PUBLISHER]

Published
2017
Full Text
View/download PDF

48. Inflammatory Bowel Disease Phenotype as Risk Factor for Cancer in a Prospective Multicentre Nested Case-Control IG-IBD Study.

Author

Biancone, Livia, Armuzzi, Alessandro, Scribano, Maria Lia, D'Inca, Renata, Castiglione, Fabiana, Papi, Claudio, Angelucci, Erika, Daperno, Marco, Mocciaro, Filippo, Riegler, Gabriele, Fries, Walter, Meucci, Gianmichele, Alvisi, Patrizia, Spina, Luisa, Ardizzone, Sandro, Petruzziello, Carmelina, Ruffa, Alessandra, Kohn, Anna, Vecchi, Maurizio, and Guidi, Luisa

Abstract

Background and Aims: Cancer risk in inflammatory bowel disease [IBD] is still debated. In a prospective, multicentre, nested case-control study, we aimed to characterise incident cases of cancer in IBD. The role of immunomodulators vs clinical characteristics of IBD as risk factors for cancer was also investigated. Materials and Methods: From January 2012 to December 2014, each IBD patient with incident cancer was matched with two IBD patients without cancer for: IBD type, gender, and age. Risk factors were assessed by multivariate regression analysis. Results: IBD patients considered numbered 44 619: 21 953 Crohn's disease [CD], 22 666 ulcerative colitis [UC]. Cancer occurred in 174 patients: 99 CD [CD-K], 75 UC [UC-K]. Controls included 198 CD [CD-C], 150 UC [UC-C]. Cancer incidence in IBD was 3.9/1000, higher in CD (4.5/1000 [99/21,953]) than in UC (3.3/1000 [75/22,666]; p = 0.042). Cancers involved: digestive system [36.8%], skin [13.2%], urinary tract [12.1%], lung [8.6%], breast [8%], genital tract [6.9%], thyroid [4.6%], lymphoma [3.5%], others [6.3%]. In CD, penetrating behaviour and combined thiopurines and tumour necrosis factor alpha [TNFα] antagonists were risk factors for cancer overall: odds ratio [OR] (95% confidence interval [CI] 2.33 [1.01-5.47]); 1.97 [1.1-3.5]; and for extracolonic cancers 3.9 [1.56-10.1]; 2.15 [1.17- 4.1], respectively. In UC, risk factors were pancolitis and disease-related surgery for cancer overall (OR: 2.52 [1.26-5.1]; 5.09 [1.73-17.1]); disease-related surgery for colorectal cancer [CRC] (OR 3.6 [1.0-12]); and extensive and left-sided vs distal UC for extracolonic cancers (OR: 2.55 [1.15-5.9]; 2.6 [1.04-6.6]), respectively. Conclusions: In a multicentre study, penetrating CD and extensive UC were risk factors for cancer overall. Cancer incidence was higher in CD than in UC. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results