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Objective: The aim of this study was to describe the inflammatory markers studied in umbilical cord blood and to analyze the performance of the three markers most frequently studied for the prediction of early-onset neonatal sepsis., Data Sources: An integrative review from 1995 to 2021 was performed, with a search in the MEDLINE, Embase, Cochrane Library, SciELO, and gray literature databases, using the terms "neonates," "newborns," "neonatal sepsis," "early-onset neonatal sepsis," "neonatal infection," "inflammatory markers," "biomarkers," "cord blood," "fetal blood.", Study Selection and Data Extractions: Study evaluation was limited to primary studies, prospective, observational or intervention, descriptive or analytical, that assessed the diagnosis of early-onset neonatal sepsis using inflammatory markers in umbilical cord blood, in Portuguese, English, or Spanish. Qualitative studies, reports, review studies, and case series were excluded. Only studies with a punctuation ≥ 6 in the Newcastle-Ottawa scale were included., Relevance to Patient Care and Clinical Practice: Sixteen studies were included in the qualitative synthesis. Procalcitonin, C-reactive protein, and interleukin-6 were the most frequently studied markers. The best performance for C-reactive protein was observed at a 0.2 mg/L cutoff, with a sensitivity of 82% and a negative predictive value of 99%. Procalcitonin presented the best performance at a 0.5 ng/mL cutoff with 87.5% sensitivity and 98.7% negative predictive value. Interleukin-6 presented the best performance at a 108.5 ng/mL cutoff, with 95% sensitivity and 97.4% negative predictive value., Conclusion: The evaluation of markers in the umbilical cord for the diagnosis of early-onset neonatal sepsis, could contribute to a more assertive therapy for the neonate and anticipate sepsis screening. Since the cost is less and technically easier, C-reactive protein is recommended for routine use.

Objective: To evaluate inadequacies in Certificates of Live Birth in a city in Southern Brazil between 2011 and 2015., Methods: This is a retrospective quantitative study based on Certificates of Live Birth of mothers living in Itapema, Santa Catarina, issued from 2011 to 2015, using data from the Live Birth Information System., Results: Among 3,537 certificates, we found no mistakes in the variables newborn's sex, birth weight, maternal age, type of pregnancy, and type of delivery. Concerning incompleteness, the variable "cesarean section was performed before the start of labor" had a mean rate considered poor, while occupation was classified as good (above 6%), neighborhood as excellent (between 0.8 and 4.5%), and induction also as excellent (0.7 to 2.9%). Inaccuracies were greater in the ethnicity (up to 0.7%) and neighborhood (up to 1.3%) variables, both considered excellent. In the comparison between sections, the pregnancy and childbirth section was the most incomplete., Conclusion: Data completeness in Certificates of Live Birth was considered excellent for most variables, and the classification of inaccuracies was excellent for all variables, evidencing the quality of the information found in these certificates.

Purpose: The objective of this research was to explore the experiences of 11 hemiplegic users with their manual wheelchairs. Method: The phenomenological approach explored the subjective experiences of Brazilian hemiplegic manual wheelchair users in order to identify and describe the factors that affected their relationship with their wheelchair. Using in depth semistructured interviews. The data were analysed using thematic analysis. The health records from the physiotherapy service of the Health Department of Itajaí were reviewed to identify hemiplegic wheelchair users. Results: The results identified 4 key themes: heteronomy, inadequate/inappropriateness of wheelchair design, poor state of the pavements and roads prohibiting wheelchair use and lack of suitable wheelchair provision. Conclusion: The findings confirm that current manual wheelchair provision, both new and secondhand, for this group of users is inadequate and they highlighted the issues and problems arising from the current provision. A novel finding was the identification of heteronomy that resulted from the provision of unsuitable equipment.Implication for rehabilitationAdding into physiotherapy and occupational therapy education, the importance of matching technology to the user in their environment.The importance of involving the user in decisions made about wheelchair provision.Sharing findings with wheelchair manufacturers to improve manual wheelchair design for hemiplegic users.

The research objective was to evaluate the association between socioeconomic and demographic variables of health-related behaviors and characteristics of the home environment and the prevalence of overweight among students from 1st to 5th grade in the city of Itajaí in the State of Santa Catarina, brazil. Socioeconomic and demographic variables were identified through a questionnaire administered to parents/guardians. Nutritional status was determined by body mass index and waist circumference. The association between excess weight and other variables was investigated using Pearson's Chi-Square and the Linear Trend test. The population consisted of 417 children, which represented 95.2% of the sample. The data suggest that 44% of children were overweight, which was associated with: a better quality diet (49.4%, p = 0.051), lower frequency of consumption of snack foods, habit of eating meals while watching the television, overweight parents (51%, p = 0,002), the score of family nutrition (51.9%, p = 0.029**) and physical activity in children. It is suggested that health actions must consider the family environment and the social context of children to promote healthier lifestyles.

The forced swim test (FST) is a pre-clinical test to short and long term treatment with antidepressant drugs (ADT), which requires between-subject designs. Herein a modified protocol of the FST using within-subject design (repeated rat-FST) was evaluated. Male Wistar rats were submitted to 15 min of swimming (Day 1: pretest) followed by three subsequent 5 min-swimming tests one week apart (Day 2: test, Day 7: retest 1, Day 14: retest 2). To determine the temporal and factorial characteristics of the variables scored in the repeated rat-FST, the protocol was carried out in untreated animals (E1). To validate the method, daily injections of Fluoxetine (FLX, 2.5mg/kg, i.p.) or saline were given over a 2-week period (E2). Tests and retests have been videotaped for further register of the latency, frequency and duration of behaviors. Over retesting the latency to immobility decreased whereas duration of immobility tended to increase. Factorial analysis revealed that the test, the retest 1 as well as the retest 2 have variables suitable to detection of antidepressant-like effects of ADT. Compared to saline, FLX chronically administrated reduced duration of immobility whereas increased duration of swimming in retest 2. The data suggest that repeated rat-FST detected the gradual increase in the efficacy of low doses of FLX over time. Therefore, repeated rat-FST seemed suitable to detect short and long term effects of selective serotonin reuptake inhibitors, or other ADT, thus reducing the number of animals used in the screenings of this type of compounds., (© 2010 Elsevier B.V. All rights reserved.)

The acerola (Malpighia emarginata Sessé y Mociño ex DC) is a wild plant grown in zones of tropical and subtropical climate. Acerola is origin from South of Mexico, Central America and Septentrional area of South America. Its scientific name was adopted in 1986 by the International Council of Vegetable Genetic Resources. Malpighia emarginata has a subglobulose drupa fruit with three seeds which account between the 19 - 25% of the total weight. The diameter and weight of the fruit varies between 1 - 4 cm and 2 - 15 g, respectively. The fruit shows green color when it is developing, which changes to yellow and red tones when it is mature. Each plant produces annually 20 - 30 kg of fruits. This fruit contents macro and micronutrients: proteins (0.21-0.80 g/100 g), fats (0.23-0.80 g/100 g), carbohydrates (3.6-7.80 g/100 g), mineral salts (iron 0.24, calcium 11.7, phosphorus 17.1 mg/100 g) and vitamins (thiamine 0.02, riboflavine 0.07, piridoxine 8.7 mg/100 g). Its high content in vitamin C (695 a 4827 mg/100 g) is remarkable, therefore acerola has an increasing economic value by its great consume during last years. Acerola also presents carotenoids and bioflavonoids which provide important nutritive value and its potential use as antioxidant. Brazil has a climate and soil appropriate for the culture of acerola, thus this country is the main mundial productor. Acerola is commercialised as juices, jams, ices, gelatins, sweets or liquors. Bibliographical data have been mainly supplied by Electronic Resources of the University of Seville and the University do Vale do Itajaí (Santa Catarina, Brazil).