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Your search keyword '"Mi, Qiwu"' showing total 13 results
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13 results on '"Mi, Qiwu"'

10. Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

Author

Ye, Zhangqun, primary, Zeng, Guohua, additional, Yang, Huan, additional, Tang, Kun, additional, Zhang, Xiaochun, additional, Li, Hong, additional, Li, Weibing, additional, Wu, Zhong, additional, Chen, Lingwu, additional, Chen, Xingfa, additional, Liu, Xiankui, additional, Deng, Yaoliang, additional, Pan, Tiejun, additional, Xing, Jinchun, additional, Wang, Shusheng, additional, Cheng, Yue, additional, Gu, Xiaojian, additional, Gao, Wenxi, additional, Yang, Jianggen, additional, Zhang, Yonghai, additional, Mi, Qiwu, additional, Qi, Lin, additional, Li, Jiongming, additional, Hu, Weilie, additional, Liang, Peiyu, additional, Sun, Zhaolin, additional, Xu, Changbao, additional, Long, Yongfu, additional, Liao, Yongbin, additional, Liu, Siping, additional, Liu, Guoqing, additional, Xu, Xun, additional, He, Wei, additional, Chen, Zhiqiang, additional, and Xu, Hua, additional

Published
2018
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11. Suprapubic-assisted umbilical laparoendoscopic mini-dual-site surgery in the treatment of simple kidney cyst: Report of 26 cases

Author

Luo, Daosheng, primary, Liu, Guihua, additional, Mo, Junhua, additional, Xiao, Lihua, additional, Xie, Qiang, additional, Li, Mu, additional, Zhang, Zengqiang, additional, Lu, Jianjun, additional, Liang, Zhenfeng, additional, Meng, Xiangjun, additional, Zhang, Yuanyuan, additional, Deng, Chunhua, additional, and Mi, Qiwu, additional

Published
2013
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12. A multicentre, prospective, randomized trial: comparative efficacy of tamsulosin and nifedipine in medical expulsive therapy for distal ureteric stones with renal colic

Author

Ye, Zhangqun, primary, Yang, Huan, additional, Li, Hong, additional, Zhang, Xiaochun, additional, Deng, Yaoliang, additional, Zeng, Guohua, additional, Chen, Lingwu, additional, Cheng, Yue, additional, Yang, Jianggen, additional, Mi, Qiwu, additional, Zhang, Yonghai, additional, Chen, Zhong, additional, Guo, Hui, additional, He, Wei, additional, and Chen, Zhiqiang, additional

Published
2010
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13. Limonene terpenoid obstructs human bladder cancer cell (T24 cell line) growth by inducing cellular apoptosis, caspase activation, G2/M phase cell cycle arrest and stops cancer metastasis.

Author

Ye Z, Liang Z, Mi Q, and Guo Y

Subjects
Cell Line, Tumor, G2 Phase Cell Cycle Checkpoints, Humans, Limonene pharmacology, M Phase Cell Cycle Checkpoints, Signal Transduction, Terpenes pharmacology, Urinary Bladder Neoplasms pathology, Apoptosis drug effects, Limonene therapeutic use, Neoplasm Metastasis drug therapy, Terpenes therapeutic use, Urinary Bladder Neoplasms drug therapy
Abstract

Purpose: The primary purpose of the current study was to investigate the antitumor activity of limonene which is a plant monoterpene along with evaluating its effects on cell apoptosis, cell cycle phase distribution, cell migration and invasion., Methods: The cell proliferation of T24 bladder cancer cells was examined by WTS-1 assay. The apoptotic effects induced by limonene were investigated by a combination of fluorescence microscopy and flow cytometry and then confirmed by western blot assay. The effects of limonene on cell cycle in T24 bladder cancer cells were studied by flow cytometry. The effects on cell migration and invasion were examined by wound healing assay and transwell assay using Matrigel., Results: The results showed that limonene induced cytotoxic effects and reduced cell viability of T24 human bladder cancer cells showing an IC50 value of 9 μM. Limonene also induced significant apoptosis in bladder cancer cells since it induced significant nuclear fragmentation, chromatin condensation, and splitting of the nucleus, representative of the apoptotic cascade. The apoptotic cell percentage was 1.95, 5.35, 15.61 and 34.71% at limonene concentrations of 0, 9, 18 and 36 µM. Further, the apoptotic effects of limonene were also confirmed by Western blot analysis and the results showed increase in the expression of Bax and caspase-3 and decrease of Bcl-2 expression. Limonene also caused G2/M phase cell cycle arrest as well as suppression of cell migration and invasion., Conclusions: These results indicate that limonene might be used as a potent anticancer agent against human bladder cancer for which further in depth studies are needed, especially over its toxicological studies.

Published
2020

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