Search

Your search keyword '"Miao, Fenglin"' showing total 28 results
Start Over Author "Miao, Fenglin"
28 results on '"Miao, Fenglin"'

3. An Improved Distributed Wind Farm MPPT Control Based on Wake Propagation Prediction

Author

Miao, Fenglin, Fan, Yi, Li, Zhen, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Tan, Kay Chen, Series Editor, Hu, Cungang, editor, and Cao, Wenping, editor

Published
2023
Full Text
View/download PDF

9. The RING-Type E3 Ubiquitin Ligase Gene GhDIRP1 Negatively Regulates Verticillium dahliae Resistance in Cotton (Gossypium hirsutum).

Author

Miao, Fenglin, Chen, Wei, Zhao, Yunlei, Zhao, Pei, Sang, Xiaohui, Lu, Jianhua, and Wang, Hongmei

Subjects
UBIQUITIN ligases, REPORTER genes, GENE expression, PROTEOLYSIS, VERTICILLIUM dahliae
Abstract

Cotton is one of the world's most important economic crops. Verticillium wilt is a devastating cotton disease caused by Verticillium dahliae, significantly impacting cotton yield and quality. E3 ubiquitin ligases are essential components of the ubiquitin-mediated 26S proteasome system, responsible for recognizing ubiquitinated target proteins and promoting their degradation, which play a crucial regulatory role in plant immune responses. In this study, on the basis of the confirmation of differential expression of GhDIRP1, a RING-type E3 ubiquitin ligase encoding gene, in two cotton varieties resistant (Zhongzhimian 2) or susceptible (Jimian 11) to V. dahliae, we demonstrated that GhDIRP1 is a negative regulator of V. dahliae resistance because silencing GhDIRP1 in cotton and heterogeneously overexpressing the gene in Arabidopsis enhanced and compromised resistance to V. dahliae, respectively. The GhDIRP1-mediated immune response seemed to be realized through multiple physiological pathways, including hormone signaling, reactive oxygen species, and lignin biosynthesis. Based on the sequences of GhDIRP1 isolated from Zhongzhimian 2 and Jimian 11, we found that GhDIRP1 had identical coding but different promoter sequences in the two varieties, with the promoter of Zhongzhimian 2 being more active than that of Jimian 11 because the former drove a stronger expression of GUS and LUC reporter genes. The results link the ubiquitination pathway to multiple physiological pathways acting in the cotton immune response and provide a candidate gene for breeding cotton varieties resistant to V. dahliae. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. Stimulator of Interferon Genes-Activated Biomimetic Dendritic Cell Nanovaccine as a Chemotherapeutic Booster to Enhance Systemic Fibrosarcoma Treatment

Author

Wang, Zhao, Miao, Fenglin, Gu, Lingwei, Zhang, Ruyi, Ma, Yuan, Li, Ying, Zheng, Jialiang, Lin, Zhenhang, Gao, Yilai, Huang, Liyong, Shen, Ye, Wu, Ting, Luo, Fanghong, and Li, Wengang

Abstract

Fibrosarcoma, a malignant mesenchymal tumor, is characterized by aggressive invasiveness and a high recurrence rate, leading to poor prognosis. Anthracycline drugs, such as doxorubicin (DOX), represent the frontline chemotherapy for fibrosarcoma, but often exhibit suboptimal efficacy. Recently, exploiting the stimulator of interferon genes (STING)-mediated innate immunity has emerged as a hopeful strategy for cancer treatment. Integrating chemotherapy with immunomodulators in chemo-immunotherapy has shown potential for enhancing treatment outcomes. Herein, we introduce an advanced dendritic cell (DC) nanovaccine, cGAMP@PLGA@CRTM (GP@CRTM), combined with low-dose DOX to enhance fibrosarcoma chemo-immunotherapy. The nanovaccine consists of poly(lactic-co-glycolic acid) (PLGA) nanoparticles encapsulating the STING agonist 2,3-cGAMP (cGAMP@PLGA, GP) as its core, and a calreticulin (CRT) high-expressing fibrosarcoma cell membrane (CRTM) as the shell. Exposing CRT on the vaccine surface aids in recruiting DCs and stimulating uptake, facilitating efficient simultaneous delivery of STING agonists and tumor antigens to DCs. This dual delivery method effectively activates the STING pathway in DCs, triggering sustained immune stimulation. Simultaneously, low-dose DOX reduces chemotherapy-related side effects, directly kills a subset of tumor cells, and increases tumor immunogenicity, thus further amplifying immune therapeutic performance. Hence, these findings demonstrate the potential of DC nanovaccine GP@CRTM as a booster for chemotherapy. Synergistically combining low-dose DOX with the DC nanovaccine emerges as a powerful chemo-immunotherapy strategy, optimizing systemic fibrosarcoma therapy.

Published
2024
Full Text
View/download PDF

15. Dynamic Ginsenoside-Sheltered Nanocatalysts for Safe Ferroptosis-Apoptosis Combined Therapy

Author

Zhao, Xiaoxiong, primary, Wu, Jicheng, additional, Guo, Danjing, additional, Hu, Shen, additional, Chen, Xiang, additional, Hong, Liangjie, additional, Wang, Junmei, additional, Ma, Jugang, additional, Jiang, Yangkang, additional, Niu, Tianye, additional, Miao, Fenglin, additional, Li, Wen-Gang, additional, Wang, Ben, additional, Chen, Xinhua, additional, and Song, Yujun, additional

Published
2022
Full Text
View/download PDF

23. Impact of Structural Flexibility on Flicker of DFIG Wind Turbine

Author

Li Qing, Miao Fenglin, He Jing, Zhang Jinping, and Qin Shiyao

Subjects
Flexibility (engineering), Wind power, Computer science, business.industry, 020209 energy, Flicker, 02 engineering and technology, Turbine, Automotive engineering, Coupling (computer programming), 0202 electrical engineering, electronic engineering, information engineering, Torque, business, Short circuit, Tower
Abstract

With the increasing unit capacity of large-scale wind turbine, blade and tower as the flexible components could have a significant influence on integration performance. Impact on the voltage fluctuation due to the structural flexibility is analyzed theoretically. And then a co-simulation platform is built based on an interface between different software, considering coupling of mechanical and electrical models. The electromechanical model with and without the consideration of bending modes of blade and tower can be obtained on this platform. By this way, the impact comparisons on flicker in different wind cases and short circuit capacities are performed. The co-simulation results show that structural flexibility could increase the flicker and the impact depends on the wind case and short circuit capacity. And the structural flexibility should be taken into account for integration performance study.

Published
2018

Catalog

Books, media, physical & digital resources
See catalog results