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1. Interim report for the International Muon Collider Collaboration (IMCC)

Author

Accettura, C., Adrian, S., Agarwal, R., Ahdida, C., Aimé, C., Aksoy, A., Alberghi, G. L., Alden, S., Amapane, N., Amorim, D., Andreetto, P., Anulli, F., Appleby, R., Apresyan, A., Asadi, P., Mahmoud, M. Attia, Auchmann, B., Back, J., Badea, A., Bae, K. J., Bahng, E. J., Balconi, L., Balli, F., Bandiera, L., Barbagallo, C., Barlow, R., Bartoli, C., Bartosik, N., Barzi, E., Batsch, F., Bauce, M., Begel, M., Berg, J. S., Bersani, A., Bertarelli, A., Bertinelli, F., Bertolin, A., Bhat, P., Bianchi, C., Bianco, M., Bishop, W., Black, K., Boattini, F., Bogacz, A., Bonesini, M., Bordini, B., de Sousa, P. Borges, Bottaro, S., Bottura, L., Boyd, S., Breschi, M., Broggi, F., Brunoldi, M., Buffat, X., Buonincontri, L., Burrows, P. N., Burt, G. C., Buttazzo, D., Caiffi, B., Calatroni, S., Calviani, M., Calzaferri, S., Calzolari, D., Cantone, C., Capdevilla, R., Carli, C., Carrelli, C., Casaburo, F., Casarsa, M., Castelli, L., Catanesi, M. G., Cavallucci, L., Cavoto, G., Celiberto, F. G., Celona, L., Cemmi, A., Ceravolo, S., Cerri, A., Cerutti, F., Cesarini, G., Cesarotti, C., Chancé, A., Charitonidis, N., Chiesa, M., Chiggiato, P., Ciccarella, V. L., Puviani, P. Cioli, Colaleo, A., Colao, F., Collamati, F., Costa, M., Craig, N., Curtin, D., D'Angelo, L., Da Molin, G., Damerau, H., Dasu, S., de Blas, J., De Curtis, S., De Gersem, H., Del Moro, T., Delahaye, J. -P., Denisov, D., Denizli, H., Dermisek, R., Valdor, P. Desiré, Desponds, C., Di Luzio, L., Di Meco, E., Di Petrillo, K. F., Di Sarcina, I., Diociaiuti, E., Dorigo, T., Dreimanis, K., Pree, T. du, Edgecock, T., Fabbri, S., Fabbrichesi, M., Farinon, S., Ferrand, G., Somoza, J. A. Ferreira, Fieg, M., Filthaut, F., Fox, P., Franceschini, R., Ximenes, R. Franqueira, Gallinaro, M., Garcia-Sciveres, M., Garcia-Tabares, L., Gargiulo, R., Garion, C., Garzelli, M. V., Gast, M., Gerber, C. E., Giambastiani, L., Gianelle, A., Gianfelice-Wendt, E., Gibson, S., Gilardoni, S., Giove, D. A., Giovinco, V., Giraldin, C., Glioti, A., Gorzawski, A., Greco, M., Grojean, C., Grudiev, A., Gschwendtner, E., Gueli, E., Guilhaudin, N., Han, C., Han, T., Hauptman, J. M., Herndon, M., Hillier, A. D., Hillman, M., Holmes, T. R., Homiller, S., Jana, S., Jindariani, S., Johannesson, S., Johnson, B., Jones, O. R., Jurj, P. -B., Kahn, Y., Kamath, R., Kario, A., Karpov, I., Kelliher, D., Kilian, W., Kitano, R., Kling, F., Kolehmainen, A., Kong, K. C., Kosse, J., Krintiras, G., Krizka, K., Kumar, N., Kvikne, E., Kyle, R., Laface, E., Lane, K., Latina, A., Lechner, A., Lee, J., Lee, L., Lee, S. W., Lefevre, T., Leonardi, E., Lerner, G., Li, P., Li, Q., Li, T., Li, W., Voti, R. Li, Lindroos, M., Lipton, R., Liu, D., Liu, M., Liu, Z., Lombardi, A., Lomte, S., Long, K., Longo, L., Lorenzo, J., Losito, R., Low, I., Lu, X., Lucchesi, D., Luo, T., Lupato, A., Métral, E., Mękała, K., Ma, Y., Mańczak, J. M., Machida, S., Madlener, T., Magaletti, L., Maggi, M., Durand, H. Mainaud, Maltoni, F., Mandurrino, M., Marchand, C., Mariani, F., Marin, S., Mariotto, S., Martin-Haugh, S., Masullo, M. R., Mauro, G. S., Mazzolari, A., Mele, B., Meloni, F., Meng, X., Mentink, M., Miceli, R., Milas, N., Mohammadi, A., Moll, D., Montella, A., Morandin, M., Morrone, M., Mulder, T., Musenich, R., Nardecchia, M., Nardi, F., Neuffer, D., Newbold, D., Novelli, D., Olvegård, M., Onel, Y., Orestano, D., Osborne, J., Otten, S., Torres, Y. M. Oviedo, Paesani, D., Griso, S. Pagan, Pagani, D., Pal, K., Palmer, M., Pampaloni, A., Panci, P., Pani, P., Papaphilippou, Y., Paparella, R., Paradisi, P., Passeri, A., Pastrone, N., Pellecchia, A., Piccinini, F., Piekarz, H., Pieloni, T., Plouin, J., Portone, A., Potamianos, K., Potdevin, J., Prestemon, S., Puig, T., Qiang, J., Quettier, L., Rabemananjara, T. R., Radicioni, E., Radogna, R., Rago, I. C., Ratkus, A., Resseguie, E., Reuter, J., Ribani, P. L., Riccardi, C., Ricciardi, S., Robens, T., Robert, Y., Roger, C., Rojo, J., Romagnoni, M., Ronald, K., Rosser, B., Rossi, C., Rossi, L., Rozanov, L., Ruhdorfer, M., Ruiz, R., Queiroz, F. S., Saini, S., Sala, F., Salierno, C., Salmi, T., Salvini, P., Salvioni, E., Sammut, N., Santini, C., Saputi, A., Sarra, I., Scarantino, G., Schneider-Muntau, H., Schulte, D., Scifo, J., Sen, T., Senatore, C., Senol, A., Sertore, D., Sestini, L., Rêgo, R. C. Silva, Simone, F. M., Skoufaris, K., Sorbello, G., Sorbi, M., Sorti, S., Soubirou, L., Spataro, D., Stamerra, A., Stapnes, S., Stark, G., Statera, M., Stechauner, B. M., Su, S., Su, W., Sun, X., Sytov, A., Tang, J., Taylor, R., Kate, H. Ten, Testoni, P., Thiele, L. S., Garcia, R. Tomas, Mugglestone, M. Topp, Torims, T., Torre, R., Tortora, L. T., Trifinopoulos, S., Udongwo, S. -A., Vai, I., Valente, R. U., van Rienen, U., van Weelderen, R., Vanwelde, M., Velev, G., Venditti, R., Vendrasco, A., Verna, A., Verweij, A., Verwilligen, P., Villamzar, Y., Vittorio, L., Vitulo, P., Vojskovic, I., Wang, D., Wang, L. -T., Wang, X., Wendt, M., Widorski, M., Wozniak, M., Wu, Y., Wulzer, A., Xie, K., Yang, Y., Yap, Y. C., Yonehara, K., Yoo, H. D., You, Z., Zanetti, M., Zaza, A., Zhang, L., Zhu, R., Zlobin, A., Zuliani, D., and Zurita, J. F.

Subjects
Physics - Accelerator Physics, High Energy Physics - Experiment
Abstract

The International Muon Collider Collaboration (IMCC) [1] was established in 2020 following the recommendations of the European Strategy for Particle Physics (ESPP) and the implementation of the European Strategy for Particle Physics-Accelerator R&D Roadmap by the Laboratory Directors Group [2], hereinafter referred to as the the European LDG roadmap. The Muon Collider Study (MuC) covers the accelerator complex, detectors and physics for a future muon collider. In 2023, European Commission support was obtained for a design study of a muon collider (MuCol) [3]. This project started on 1st March 2023, with work-packages aligned with the overall muon collider studies. In preparation of and during the 2021-22 U.S. Snowmass process, the muon collider project parameters, technical studies and physics performance studies were performed and presented in great detail. Recently, the P5 panel [4] in the U.S. recommended a muon collider R&D, proposed to join the IMCC and envisages that the U.S. should prepare to host a muon collider, calling this their "muon shot". In the past, the U.S. Muon Accelerator Programme (MAP) [5] has been instrumental in studies of concepts and technologies for a muon collider., Comment: This document summarises the International Muon Collider Collaboration (IMCC) progress and status of the Muon Collider R&D programme

Published
2024

2. Identification of hemodynamically stable patients with acute pulmonary embolism at high risk for death: external validation of different models

Author

Becattini, Cecilia, Gulizia, Michele M., Agnelli, Giancarlo, Dentali, Francesco, Di Lenarda, Andrea, Enea, Iolanda, Fabbri, Andrea, Maggioni, Aldo P., Pomero, Fulvio, Ruggeri, Maria Pia, Lucci, Donata, Vedovati, Maria Cristina, Duranti, Michele, Guercini, Francesco, Groff, Paolo, Verso, Melina, Fabbri, Gianna, Savoia, Martina, Baldini, Ester, Mecatti, Barbara Bartolomei, Bianchini, Francesca, Ceseri, Martina, Gonzini, Lucio, Gorini, Marco, Lorimer, Andrea, Orsini, Giampietro, Tricoli, Martina, Cimini, L.A., Becattini, C., Agnelli, G., Cesarini, V., Sanna, M., Pepe, G., Marchetti, C., Roldan, M. Olivan, Lenzi, L., Cozzio, S., Tomio, P., Diamanti, M., Beltrame, A., Glinski, L., Treleani, M., Coppa, A., Vanni, S., Bartalucci, P., Taccone, A., Costacurta, C., Bortolotti, P., Bortolussi, M., De Vecchi, M., Zanardi, F., Greco, I., Cosentini, R., Gerloni, R., Artusi, N., Cominotto, F., Sisto, U.G., Picariello, C., Roncon, L., Maddalozzo, A., Nitti, C., Riccomi, F., Buzzo, M., Bassanelli, G., Savonitto, S., Bianchi, A., Bilato, C., Lobascio, I., Dalla Valle, C., Pomata, D.P., Giostra, F., Tinuper, A.L., Zalunardo, B., Visonà, A., Panzavolta, C., Novelli, A., Bertini, A., Granai, C., Colombo, S., Periti, E., Bonacchini, L., Abrignani, M.G., Casciolo, M.F., D'Amato, A., Scardovi, A.B., Ricci, R., Iosi, S., Fontana, M.C., Marrazzo, A., Borselli, M., Di Fusco, S.A., Colivicchi, F., Enea, I., Triggiani, M., Papa, I., Pasini, G.F., Fioravanti, C., Panarello, S., Raggi, F., Marzolo, M., Cuppini, S., Milan, M., Barchetti, M., De Laura, D., Caldarola, P., Fiorini, R., Rastelli, G., Ameri, P., La Malfa, G., Cinelli, F., Sganzerla, P.C., Ubaldi, S., Sanchez, F.A., Forgione, C., Cuccia, C., Predieri, S., Fusco, S., Mumoli, N., Porta, C., Romei, M., Lucidi, M., Romaniello, A., Volpe, M., Mogni, P., Pizzolato, E., Martino, G.P., Bitti, G., Righini, G., Bandiera, G., Pennacchio, E., Limauro, S., Dachille, A., Ignone, G., Fuscaldo, G.F., De Rosa, F.M., Vazzana, N., Chesi, G., Di Filippo, F., Pierpaoli, L., Corapi, A., Vatrano, M., Angotti, C., Baccetti, F., Harari, S.A., Luisi, F., Daghini, E., De Curtis, E., Lucà, F., Ciancia, F., Blandizzi, S., Lettica, G.V., D'Orazio, S., Cosmi, F., Zaccaroni, S., Silingardi, M., Valeriano, V., Pugliese, F.R., Murgia, A.P., Parpaglia, P. Pinna, Martinelli, L., Caponi, C., Clemente, M.A., Ciccarone, A., Bongarzoni, A., Garagiola, M., Leone, M.C., Veropalumbo, M.R., Sacco, M., Morella, P., Dorigoni, S., Peterlana, D., Di Paola, R., Felis, S., Correale, M., Brunetti, N.D., Petrelli, G., Feliziani, F.T., Mastroiacovo, D., Romualdi, R., Pasin, F., Bonardi, S., Delfino, P., Scifo, C., Savioli, G., Ceresa, I.F., Galeotalanza, M., Benazzi, B., Porzio, M., Rosini, F., Ancona, C., Verrelli, C., Pasini, A. Fratta, Dalle Carbonare, L., Bozza, N., Nacci, F., Scarabelli, M.A., Amico, F., Marchesi, C., Mazzone, A., Di Tommaso, R., Cocco, F., Pezzuto, G., Luciani, A., Zamboni, P., Muriago, M., Del Pesce, L., Lucarini, A.R., Guglielmelli, E., Vannucchi, V., Moroni, F., Fichera, D., Malatino, L., Sgroi, C., Morana, I.M., Cicero, S., La Rosa, D., Mete, F., Gino, M., De Palma, A., Alessandri, M., Maestripieri, V., Battocchio, M., De Santis, M.T., Saladini, F., Corsi, D.C., Macarone Palmieri, N., Pierfranceschi, M. Giorgi, Palmonari, V., Fontanella, L., Airoldi, L., Bonocore, M., Paliani, U., Prat, L. Iogna, Chiecchi, L., Cuonzo, M., Paludo, A., Padula, D., Antonelli, A., Bicchi, M., Tota, G., Ariello, M., Sai, R., Civita, M., Tucci, M., Barbati, G., Conti, M., Cettina, R., Magnani, O., Levato, M., Gessi, V., De Rui, M., Bellizzi, A., Farneti, L., Salomone, P., Mannarini, A., Grifoni, E., Del Ghianda, S., Campodonico, J., De Cesare, N., Mutone, D., Pasoli, P., Meloni, S., Frenda, A., Viola, G., Torromeo, C., Campana, C., Pistone, M.C., Caravita, S., La Creta, C.P., Miscio, F., Loreno, M., Fenu, P., Mazzetti, M., Rossini, D., Brunacci, M., Capuano, A., Tagliamonte, G., Pinelli, M., Ballocca, F., Parca, G., Pasini, S.M., Maragno, M.G., Vecchi, F., Mancinelli, L., Cavalli, A., Di Mare, F., Conficoni, E., Miceli, R., Pecoraro, R., Fonti, C., Pegoraro, S., Piccinni, G.C., Caruso, G., Boriani, G., Lanzillotta, P., Piccolo, P., Calò, L., Stolfo, D., Mangiacapra, S., Marziali, A., Volponi, M.C., Querci, G., Terribile, R., Menabue, M., Fiorentini, A., Musci, R.L., Uras, S., Cicini, M.P., Manetti, S., Francese, G.M., Melchio, R., Scorpiglione, N., Carrara, D., Pani, A., Morisco, C., Rodolico, M., Colombo, Silvia, Vanni, Simone, Abrignani, Maurizio Giuseppe, Scardovi, Angela Beatrice, Marrazzo, Alessandra, Borselli, Matteo, Barchetti, Marco, and Maggioni, Aldo Pietro

Published
2024
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7. Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts

Author

Stacchiotti, S., Miah, A.B., Frezza, A.M., Messiou, C., Morosi, C., Caraceni, A., Antonescu, C.R., Bajpai, J., Baldini, E., Bauer, S., Biagini, R., Bielack, S., Blay, J.Y., Bonvalot, S., Boukovinas, I., Bovee, J.V.M.G., Boye, K., Brodowicz, T., Callegaro, D., De Alava, E., Deoras-Sutliff, M., Dufresne, A., Eriksson, M., Errani, C., Fedenko, A., Ferraresi, V., Ferrari, A., Fletcher, C.D.M., Garcia del Muro, X., Gelderblom, H., Gladdy, R.A., Gouin, F., Grignani, G., Gutkovich, J., Haas, R., Hindi, N., Hohenberger, P., Huang, P., Joensuu, H., Jones, R.L., Jungels, C., Kasper, B., Kawai, A., Le Cesne, A., Le Grange, F., Leithner, A., Leonard, H., Lopez Pousa, A., Martin Broto, J., Merimsky, O., Merriam, P., Miceli, R., Mir, O., Molinari, M., Montemurro, M., Oldani, G., Palmerini, E., Pantaleo, M.A., Patel, S., Piperno-Neumann, S., Raut, C.P., Ravi, V., Razak, A.R.A., Reichardt, P., Rubin, B.P., Rutkowski, P., Safwat, A.A., Sangalli, C., Sapisochin, G., Sbaraglia, M., Scheipl, S., Schöffski, P., Strauss, D., Strauss, S.J., Sundby Hall, K., Tap, W.D., Trama, A., Tweddle, A., van der Graaf, W.T.A., Van De Sande, M.A.J., Van Houdt, W., van Oortmerssen, G., Wagner, A.J., Wartenberg, M., Wood, J., Zaffaroni, N., Zimmermann, C., Casali, P.G., Dei Tos, A.P., and Gronchi, A.

Published
2021
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10. Axicabtagene ciloleucel treatment is more effective in primary mediastinal large B-cell lymphomas than in diffuse large B-cell lymphomas: the Italian CART-SIE study

Author

Chiappella, A., Casadei, B., Chiusolo, Patrizia, Di Rocco, A., Ljevar, S., Magni, M., Angelillo, P., Barbui, A. M., Cutini, I., Dodero, A., Bonifazi, F., Tisi, M. C., Bramanti, S., Musso, M., Farina, M., Martino, M., Novo, M., Grillo, G., Patriarca, F., Zacchi, G., Krampera, M., Pennisi, M., Galli, Eugenio, Martelli, M., Ferreri, A. J. M., Ferrari, S., Saccardi, R., Bermema, A., Guidetti, A., Miceli, R., Zinzani, P. L., Corradini, P., Chiusolo P. (ORCID:0000-0002-1355-1587), Galli E., Chiappella, A., Casadei, B., Chiusolo, Patrizia, Di Rocco, A., Ljevar, S., Magni, M., Angelillo, P., Barbui, A. M., Cutini, I., Dodero, A., Bonifazi, F., Tisi, M. C., Bramanti, S., Musso, M., Farina, M., Martino, M., Novo, M., Grillo, G., Patriarca, F., Zacchi, G., Krampera, M., Pennisi, M., Galli, Eugenio, Martelli, M., Ferreri, A. J. M., Ferrari, S., Saccardi, R., Bermema, A., Guidetti, A., Miceli, R., Zinzani, P. L., Corradini, P., Chiusolo P. (ORCID:0000-0002-1355-1587), and Galli E.

Abstract

Axicabtagene ciloleucel showed efficacy for relapsed/refractory large B-cell lymphomas (LBCL), including primary mediastinal B-cell lymphomas (PMBCL); however, only few PMBCLs were reported. Aim was to evaluate efficacy and safety of axicabtagene ciloleucel in patients with PMBCL compared to those with other LBCL, enrolled in the Italian prospective observational CART-SIE study. PMBCLs (n = 70) were younger, with higher percentage of bulky and refractory disease, compared to other LBCLs (n = 190). Median follow-up time for infused patients was 12.17 months (IQR 5.53,22.73). The overall (complete + partial) response rate (ORR,CR + PR) after bridging was 41% for PMBCL and 28% for other LBCL, p = 0.0102. Thirty days ORR was 78% (53/68) with 50% (34) CR in PMBCL, and 75% (141/187) with 53% (100) CR in other LBCL, p = 0.5457. Ninety days ORR was 69% (45/65) with 65% (42) CR in PMBCL, and 54% (87/162) with 47% (76) CR in other LBCL; progressive disease was 21% in PMBCL and 45% in other LBCL, p = 0.0336. Twelve months progression-free survival was 62% (95% CI: 51–75) in PMBCL versus 48% (95% CI: 41–57) in other LBCL, p = 0.0386. Twelve months overall survival was 86% (95% CI: 78–95) in PMBCL versus 71% (95% CI: 64–79) in other LBCL, p = 0.0034. All grade cytokine release syndrome was 88% (228/260); all grade neurotoxicity was 34% (88/260), with 6% of fatal events in PMBCL. Non-relapse mortality was 3%. In conclusion, PMBCLs achieved significantly better response and survival rates than other LBCLs.

Published
2024

11. Low-grade fibromyxoid sarcoma and sclerosing epithelioid fibrosarcoma, outcome of advanced disease: retrospective study from the Ultra-Rare Sarcoma Working Group

Author

Giani, C., Denu, R.A., Ljevar, S., Gronchi, A., Napolitano, A., Rosenbaum, E., Salawu, A., Bajpai, J., Connolly, E.A., Lee, A.T.J., Trent, J.C., Koseła-Paterczyk, H., Chia-Chen Li, Z., Ogura, K., Palmerini, E., Baldi, G.G., Brunello, A., Campos, F., Cicala, C.M., Maki, R.G., Wagner, A.J., Andelkovic, V., Loong, H.H., Wong, D.D., Jones, R.L., Tap, W.D., Taverna, S.M., Lazar, A.J., Demicco, E.G., Hong, A., Bovee, J.V.M.G., Dei Tos, A.P., Fletcher, C.D.M., Baumhoer, D., Sbaraglia, M., Schaefer, I.M., Miceli, R., and Stacchiotti, S.

Published
2024
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14. Efficacy and safety of single-agent pan-human epidermal growth factor receptor (HER) inhibitor dacomitinib in locally advanced unresectable or metastatic skin squamous cell cancer

Author

Cavalieri, S., Perrone, F., Miceli, R., Ascierto, P.A., Locati, L.D., Bergamini, C., Granata, R., Alfieri, S., Resteghini, C., Galbiati, D., Busico, A., Paielli, N., Patuzzo, R., Maurichi, A., Gallino, G., Ruggeri, R., Mariani, L., Palla, M., Licitra, L., and Bossi, P.

Published
2018
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18. The Italian CART‐SIE real life multicenter observational study on Chimeric Antigen Receptor T‐cell (CAR‐T) therapy for large B‐cell (LBCL) and mantle cell (MCL) lymphomas

Author

Chiappella, A., primary, Dodero, A., additional, Ljevar, S., additional, Pennisi, M., additional, Bonifazi, F., additional, De Philippis, C., additional, Galli, E., additional, Di Rocco, A., additional, Tisi, M. C., additional, Cutini, I., additional, Carrabba, M. G., additional, Musso, M., additional, Martino, M., additional, Barbui, A. M., additional, Botto, B., additional, Farina, M., additional, Grillo, G., additional, Patriarca, F., additional, Ladetto, M., additional, Arcaini, L., additional, Bermema, A., additional, Miceli, R., additional, Magni, M., additional, Zinzani, P. L., additional, Bramanti, S., additional, Chiusolo, P., additional, Martelli, M., additional, Carniti, C., additional, and Corradini, P., additional

Published
2023
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19. A randomized, phase 2 study of cetuximab plus cisplatin with or without paclitaxel for the first-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck

Author

Bossi, P., Miceli, R., Locati, L.D., Ferrari, D., Vecchio, S., Moretti, G., Denaro, N., Caponigro, F., Airoldi, M., Moro, C., Vaccher, E., Sponghini, A., Caldara, A., Rinaldi, G., Ferrau, F., Nolè, F., Lo Vullo, S., Tettamanzi, F., Hollander, L., and Licitra, L.

Published
2017
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22. Estimating 12-week death probability in patients with refractory metastatic colorectal cancer: the Colon Life nomogram

Author

Pietrantonio, F., Miceli, R., Rimassa, L., Lonardi, S., Aprile, G., Mennitto, A., Marmorino, F., Bozzarelli, S., Antonuzzo, L., Tamburini, E., Morano, F., Rossini, D., Battaglin, F., Baretti, M., Berenato, R., Formica, V., Mosconi, S., Petrelli, F., Ghidini, M., Loupakis, F., Spada, D., Cinieri, S., Beretta, G., Falcone, A., de Braud, F., and Cremolini, C.

Published
2017
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25. Design and Validation of a Dynamic Inductive Power Transfer System for EV Battery Charging

Author

Busacca A., Di Tommaso A. O., Campagna N., Miceli R., Castiglia V., Valtchev S., Busacca A., Di Tommaso A.O., Campagna N., Miceli R., Castiglia V., and Valtchev S.

Subjects
Vehicle Charging, Wireless Power Transfer, Settore ING-IND/32 - Convertitori, Macchine E Azionamenti Elettrici, Inductive Power Transfer, Energy Conversion
Abstract

In this paper, a Dynamic Resonant Inductive Power Transfer (DRIPT) System for the Electric Vehicle (EV) battery charging is proposed. In particular, the aim of the work is the general design of the whole system and its validation, with particular attention to the power electronic converters and their control. For the transmitter side, a DC/AC converter is used. It is controlled through the phase-shift technique and supervised by a Zero Phase Angle detection algorithm to ensure the maximum power transfer. For the receiver side, a double conversion stage, consisting of a diode rectifier and a controlled buck converter, is provided. The system is then simulated to verify its proper design.

Published
2022

26. A Simple Software-based Resolver To Digital Conversion System

Author

Di Tommaso A. O., Miceli R., Nevoloso C., Scaglione G., Schettino G., Buccella C., Cecati C., Di Tommaso A.O., Miceli R., Nevoloso C., Scaglione G., Schettino G., Buccella C., and Cecati C.

Subjects
Resolver to Digital Converter, Settore ING-IND/32 - Convertitori, Macchine E Azionamenti Elettrici, Resolver, speed measurement, Electric Drives
Abstract

In this paper, a software-based resolver to digital converter (RDC) is proposed. The hardware signal conditioning circuit is realized using common electronic components, while the algorithm can be implemented either using a microcontroller or an FPGA. Its validation and performance analysis has been carried out using an interior permanent magnet synchronous machine drive and, with comparative purposes, an LTN Servotechnik 1024 ppr incremental encoder. Tests show that the proposed RDC is characterized by a good dynamic response and precision, moreover, due to low computational demand, it can be successfully adopted without significant extra cost.

Published
2022

27. Virtual Synchronous Generator: An application to Microgrid Stability

Author

Ala G., Di Tommaso A. O., Miceli R., Nevoloso C., Scaglione G., Schettino G., Viola F., Ala G., Di Tommaso A.O., Miceli R., Nevoloso C., Scaglione G., Schettino G., and Viola F.

Subjects
Park transformation, Virtual synchronous generator, Settore ING-IND/32 - Convertitori, Macchine E Azionamenti Elettrici, synchronverter
Abstract

The objective of this paper is to illustrate an alternative control algorithm for power converters which have the task of introducing the energy generated by systems based on the use of renewable sources such as photovoltaic or wind power, into small-sized networks, microgrids. Virtual Synchronous Generator can operate both in parallel to the main network as well as in isolated and autonomous conditions (islanding-mode). The contribute of this work is to drive a consolidated approach, made in the time domain, in a more flexible and less time-consuming approach based on Park transformation

Published
2022

28. Cascaded H-Bridges Multilevel Inverter Drive: Active Power Analysis in Frequency Domain

Author

Di Tommaso A. O., Miceli R., Nevoloso C., Scaglione G., Schettino G., Spataro C., Di Tommaso A.O., Miceli R., Nevoloso C., Scaglione G., Schettino G., and Spataro C.

Subjects
CHBMI, Power drive systems, Power quality, Efficiency, Settore ING-IND/32 - Convertitori, Macchine E Azionamenti Elettrici, Power Loss
Abstract

The international standard IEC 61800-9-2 introduces energy efficiency classification for frequency converters or complete drive module (CDM) and provides instrumentation minimum requirements for accurate measurement of CDM input and output power valid for conventional pulse-width-modulated (PWM) voltage source inverter (VSI). This paper highlights the necessary improvements to update the standard with more detailed prescriptions according to the converter topologies and the modulation techniques adopted. In this framework, this paper address the power analysis in the frequency domain of a cascaded H-bridges-multilevel inverter (CHBMI) in an interior permanent magnet synchronous motor (IPMSM) drive for the identification of the minimum measurement bandwidth. The power spectrums are analyzed for different modulation strategies, different switching frequency values and IPMSM working conditions.

Published
2022

29. Challenges for the Goal of 100% Renewable Energy Sources to Fit the Green Transition

Author

Campagna N., Caruso M., Castiglia V., Di Tommaso A. O., Miceli R., Nevoloso C., Pellitteri F., Scaglione G., Schettino G., Viola F., Campagna N., Caruso M., Castiglia V., Di Tommaso A.O., Miceli R., Nevoloso C., Pellitteri F., Scaglione G., Schettino G., and Viola F.

Subjects
Renewable Sources, Green Transition, Settore ING-IND/32 - Convertitori, Macchine E Azionamenti Elettrici, Smart Inverters
Abstract

The increasing penetration of Renewable Energy (RE) into the electrical market is desirable in terms of sustainability. Nevertheless, it is a challenge that all the interested actors shall address from both the technical and economical points of view. This paper provides an overview of the main challenges and solutions towards the technological transition to an electrical system with 100% renewable energy sources in terms of innovations and operative limits of the traditional systems. These innovative paradigms will also address the social impact and government policies.

Published
2022

30. A Configuration of 3-phase Traction Inverter Employing {SiC} Devices

Author

Pellitteri F., Di Tommaso A. O., Miceli R., Rizzo R., Vassallo G., Pellitteri F., Di Tommaso A.O., Miceli R., Rizzo R., and Vassallo G.

Subjects
SiC devices, Cascode connection, traction inverter
Abstract

In the scenario of a more and more sustainable society, an increasing electrification in different fields, such as mobility and industrial applications, is foreseen in the next decades. As far as power electronics is concerned, a challenging perspective is represented by achieving higher and higher switching frequencies while maintaining high voltage and low power losses. To do that, emerging semiconductor technologies are supposed to be increasingly employed, as well as innovative topologies of connections among switching devices. Among them, the cascode configuration can notably contribute to achieve high levels of dV/dt without losing efficiency. In this paper, a 3-phase Pulse Width Modulated (PWM) inverter based on a cascode connection for each of its six switches is proposed and some promising experimental results are provided. SiC technology has been used for each power device, while a normally-off/normally-on combination of switching devices has been selected to implement the cascode-based switch.

Published
2022

31. Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab

Author

Falvella, F S, Cremolini, C, Miceli, R, Nichetti, F, Cheli, S, Antoniotti, C, Infante, G, Martinetti, A, Marmorino, F, Sottotetti, E, Berenato, R, Caporale, M, Colombo, A, de Braud, F, Di Bartolomeo, M, Clementi, E, Loupakis, F, and Pietrantonio, F

Published
2017
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37. 2014P Overall survival (OS) results in phase II trial of cabozantinib (CABO) plus durvalumab (DURVA) in patients with urothelial carcinoma (UC) or non-UC variant histologies (VH) after platinum chemotherapy (ARCADIA)

Author

Giannatempo, P., Polymeropoulos, A., Stellato, M., Ambrosini, P., Gusmaroli, E., Cavalli, C., Guadalupi, V., Claps, M., Raggi, D., Rametta, A., Ortega, C., Tucci, M., Buti, S., Pipitone, S., Iacovelli, R., Calareso, G., Alessi, A., Procopio, G., Miceli, R., and Necchi, A.

Published
2024
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38. 1981P Cabozantinib plus durvalumab in patients with advanced and chemotherapy-treated urothelial carcinoma (UC) and variant histology (VH): An open-label, phase II, single-arm proof-of-concept trial: ARCADIA study. Subgroup analysis for bone metastasis

Author

Stellato, M., Giannatempo, P., Polymeropoulos, A., Guadalupi, V., Claps, M., Ambrosini, P., Raggi, D., Rametta, A., Cavalli, C., Gusmaroli, E., Ortega, C., Tucci, M., Buti, S., Pipitone, S., Iacovelli, R., Calareso, G., Alessi, A., Procopio, G., Miceli, R., and Necchi, A.

Published
2024
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42. Enhanced modulation strategy for 7-level voltage waveform in asymmetrical 5-level Cascaded H-Bridge Inverters

Author

Di Tommaso A. O., Miceli R., Nevoloso C., Scaglione G., Schettino G., Viola F., Buccella C., Cecati C., Cimoroni G., Di Tommaso A.O., Miceli R., Nevoloso C., Scaglione G., Schettino G., Viola F., Buccella C., Cecati C., and Cimoroni G.

Subjects
SHE or SHM algorithms, Dead time, THD, Settore ING-IND/32 - Convertitori, Macchine E Azionamenti Elettrici, Asymmetrical Cascaded H-Bridge Inverter, Modulation techniques
Abstract

The CHBMI performance optimization can be reached both with hardware and software solutions. Generally, asymmetrical configurations allow the extension of the voltage levels number and the implementation of an innovative modulation strategy allows for improving the performance in terms of harmonic distortion and conversion efficiency. This work is devoted to the development of a modulation strategy that allows improving the performance of an asymmetrical single-phase five-level Cascaded H-Bridge Inverter generating a 7-level voltage waveform. Thus, a digital approach and corresponding digital functions are presented. Subsequently, the impact of the dead time and the influence on the voltage harmonic distortion have been discussed. Through simulation analysis, in the Matlab environment, the main benefits and drawbacks of the proposed approach have been discussed.

Published
2022

43. Prognostic impact of progression to induction chemotherapy and prior paclitaxel therapy in patients with germ cell tumors receiving salvage high-dose chemotherapy in the last 10 years: a study of the European Society for Blood and Marrow Transplantation Solid Tumors Working Party

Author

Necchi, A, Miceli, R, Bregni, M, Bokemeyer, C, Berger, L A, Oechsle, K, Schumacher, K, Kanfer, E, Bourhis, J H, Massard, C, Laszlo, D, Montoro, J, Flechon, A, Arpaci, F, Secondino, S, Wuchter, P, Dreger, P, Crysandt, M, Worel, N, Kruger, W, Ringhoffer, M, Unal, A, Nagler, A, Campos, A, Wahlin, A, Michieli, M, Sucak, G, Donnini, I, Schots, R, Ifrah, N, Badoglio, M, Martino, M, Raggi, D, Giannatempo, P, Rosti, G, Pedrazzoli, P, and Lanza, F

Published
2016
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45. P.020 Long-term safety and tolerability of atogepant 60mg once daily for preventive treatment of migraine: a phase 3, 40-week, multicenter extension to the advance trial

Author

Klein, B, primary, Miceli, R, additional, Severt, L, additional, McAllister, P, additional, Mechtler, L, additional, McVige, J, additional, Diamond, M, additional, Marmura, MJ, additional, Leroux, E, additional, Guo, H, additional, Finnegan, M, additional, and Trugman, J, additional

Published
2022
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47. Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab

Author

Falvella, F S, Cremolini, C, Miceli, R, Nichetti, F, Cheli, S, Antoniotti, C, Infante, G, Martinetti, A, Marmorino, F, Sottotetti, E, Berenato, R, Caporale, M, Colombo, A, de Braud, F, Di Bartolomeo, M, Clementi, E, Loupakis, F, and Pietrantonio, F

Published
2016
Full Text
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48. COVID-19 outbreak in Lombardy: Impact on reducing solid cancer diagnoses in 2020

Author

Trama, A, Bernasconi, A, Botta, L, Di Cosimo, S, Miceli, R, Claps, M, Badenchini, F, Lillini, R, Rubino, M, Lasalvia, P, Trama, Annalisa, Bernasconi, Alice, Botta, Laura, Di Cosimo, Serena, Miceli, Rosalba, Claps, Melanie, Badenchini, Fabio, Lillini, Roberto, Rubino, Massimiliano, Lasalvia, Paolo, Trama, A, Bernasconi, A, Botta, L, Di Cosimo, S, Miceli, R, Claps, M, Badenchini, F, Lillini, R, Rubino, M, Lasalvia, P, Trama, Annalisa, Bernasconi, Alice, Botta, Laura, Di Cosimo, Serena, Miceli, Rosalba, Claps, Melanie, Badenchini, Fabio, Lillini, Roberto, Rubino, Massimiliano, and Lasalvia, Paolo

Abstract

Our aim was to analyse, on a population level, the year-long decline in cancer diagnoses in the region of Lombardy (Italy), and to characterise the tumours with the greatest reduction in diagnosis by patient age, sex and tumour stage at diagnosis. We used the health care utilisation databases of the Lombardy region to identify cancer patients' characteristics (eg, sex, age) and cancer-related information (eg, cancer site, stage at diagnosis). The frequency of new cancer diagnoses in 2019 and 2020 were compared in terms of percentage differences in undiagnosed cases. We observed two peaks in the decline in cancer diagnoses: March to May 2020 (−37%) and October to December 2020 (−19%). The decline persisted over the course of 2020 and was higher in males and patients aged 74+. Diagnoses of all four common cancers analysed (female breast, lung, colorectal and prostate) remained below pre-pandemic levels. For breast and colorectal cancers, the decline in diagnoses was high in the age groups targeted by population-based screening programmes. We observed a reduction in localised stage cancer diagnoses for all four cancers. Our data confirm that timely monitoring of cancer diagnoses and interventions to prevent disruption of routine diagnostic services are needed to mitigate the impact of emergencies on cancer patients.

Published
2022

49. La fase istruttoria e le c.d. prove atipiche o illecite

Author

Consolo, C, Basilavecchia, M, Fichera, G, Castaldi, L, Miceli, R, Guida, R, Rasi, F, Fasano, A, Balsamo, M, Schiavolin, R, Sartori, N, Pistolesi, F, Marini, G, Corrado Oliva, C, Tedoldi, A, Perrino, AM, Saija, S, Zuffi, B, De Bellis, G, Trivellin, M, Melis, G, Golisano, M, Piccininni, L, Manzon, E, Vincenti, E, Consolo, G, Natalini, A, Perrino, A.M., Sartori N, Consolo, C, Basilavecchia, M, Fichera, G, Castaldi, L, Miceli, R, Guida, R, Rasi, F, Fasano, A, Balsamo, M, Schiavolin, R, Sartori, N, Pistolesi, F, Marini, G, Corrado Oliva, C, Tedoldi, A, Perrino, AM, Saija, S, Zuffi, B, De Bellis, G, Trivellin, M, Melis, G, Golisano, M, Piccininni, L, Manzon, E, Vincenti, E, Consolo, G, Natalini, A, Perrino, A.M., and Sartori N

Published
2022

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