1. A case of central odontogenic fibroma of the mandible in a nevoid basal cell carcinoma syndrome patient
- Author
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Yohei Kawasaki, Yutaka Maruoka, Junko Kindaichi, Yasuyuki Shimada, and Michita Tayama
- Subjects
Pathology ,medicine.medical_specialty ,business.industry ,Mandible ,Nevoid basal-cell carcinoma syndrome ,030206 dentistry ,medicine.disease ,Odontogenic ,Surgical methods ,stomatognathic diseases ,03 medical and health sciences ,0302 clinical medicine ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Central odontogenic fibroma ,medicine ,Keratocyst ,medicine.symptom ,business - Abstract
Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by tumorigenesis and physical deformities. Although more than 50 clinical manifestations have been described, only two major criteria or one major and two minor criteria are necessary for diagnosis. The most frequently observed manifestation in the oral and the maxillofacial region is an odontogenic keratocyst. In this study, we describe a 14-year-old boy with a diagnosis of NBCCS who presented with a central odontogenic fibroma (COF) in the mandible. This report highlights the importance of precise diagnosis and the choice of surgical method for COF.
- Published
- 2018