Search

Your search keyword '"Mike Mohutsky"' showing total 2 results
Start Over Author "Mike Mohutsky"
2 results on '"Mike Mohutsky"'

1. Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug–Drug Interaction Risk Profile

Author

Junliang Hao, James Beck, Xin Zhou, Gregory L. Lackner, Richard Johnston, Matt Reinhard, Paul Goldsmith, Sean Hollinshead, Veronique Dehlinger, Sandra A. Filla, Xu-shan Wang, Jeffery Richardson, Maria Posada, Mike Mohutsky, Doug Schober, Jason S. Katner, Qi Chen, Bingjie Hu, David M. Remick, David A. Coates, Brian M. Mathes, Mai K. Hawk, Kjell A. Svensson, and Erik Hembre

Subjects
Neuroprotective Agents, Allosteric Regulation, Receptors, Dopamine D1, Drug Discovery, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Humans, Molecular Medicine, Drug Interactions
Abstract

Results from recently completed clinical studies suggest the dopamine D1 receptor positive allosteric modulator (PAM) mevidalen (

Published
2022

2. Evaluation of the time-course of CYP Induction and impact on drug interaction risk assessment from the IQ Induction working group

Author

Kelly Nulick, Niresh Hariparsad, Jane R. Kenny, Barry Jones, Donald J. Tweedie, Theunis C. Goosen, Heidi J. Einolf, Shannon Dallas, David B. Buckley, Diane Ramsden, Josh Dekeyser, George Zhang, Jairam Palamanda, Phillip D. Yates, Mike Mohutsky, Amy Siu, and Simon Wong

Subjects
Pharmacology, medicine.medical_specialty, business.industry, Group (mathematics), Internal medicine, Time course, Pharmaceutical Science, Medicine, Pharmacology (medical), Drug interaction, business, Risk assessment
Published
2019

Catalog

Books, media, physical & digital resources
See catalog results