257 results on '"Milelli, Andrea"'
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2. First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease
3. Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer.
4. Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer
5. Pollutants and Drugs: Interactions and Human Health
6. Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives
7. From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs
8. Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease
9. Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors
10. Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains
11. Transglutaminases, neuronal cell death and neural repair: implications for traumatic brain injury and therapeutics
12. PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease
13. Hetero-bifunctional molecules as possible therapeutics for the treatment of Alzheimer’s disease.
14. Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate
15. Direct determination of GSK-3β activity and inhibition by UHPLC-UV–vis diode arrays detector (DAD)
16. Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancerElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d4md00175c
17. Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma
18. Macrocyclic naphthalene diimides as G-quadruplex binders
19. Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists
20. Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery
21. Pollutants and Drugs: Interactions and Human Health
22. Novel polyamine analogues: From substrates towards potential inhibitors of monoamine oxidases
23. Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies
24. Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
25. Synthetic polyamines activating autophagy: Effects on cancer cell death
26. Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists
27. Structure–activity relationships of novel substituted naphthalene diimides as anticancer agents
28. Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality
29. Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer’s disease
30. Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists †.
31. Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study
32. Synthetic polyamines: an overview of their multiple biological activities
33. Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder
34. Structure–activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties
35. Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer’s Disease Multitarget Drug Discovery?
36. Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors
37. Overview of the Anticancer Profile of Avenanthramides from Oat
38. Correction to “Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer’s Disease”
39. Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach
40. Deuterium Incorporation Protects Cells from Oxidative Damage
41. Investigating in Vitro Amyloid Peptide 1–42 Aggregation: Impact of Higher Molecular Weight Stable Adducts
42. Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery?
43. Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer’s Disease
44. Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase
45. Perspectives in Designing Multifunctional Molecules in Antipsychotic Drug Discovery
46. Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?
47. Farmaci Tiroidei
48. Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death
49. Application of ESI-MS method for detailed characterization of GSK-3β inhibitors by monitoring GSM peptide phosphorylation.Angelini Farmaceutici
50. Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors
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