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Your search keyword '"Milhim, Bruno H. G. A."' showing total 11 results
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11 results on '"Milhim, Bruno H. G. A."'

1. Impact of SARS-CoV-2 Gamma lineage introduction and COVID-19 vaccination on the epidemiological landscape of a Brazilian city

Author

Banho, Cecília Artico, Sacchetto, Lívia, Campos, Guilherme Rodrigues Fernandes, Bittar, Cíntia, Possebon, Fábio Sossai, Ullmann, Leila Sabrina, Marques, Beatriz de Carvalho, da Silva, Gislaine Ceslestino Dutra, Moraes, Marília Mazzi, Parra, Maisa Carla Pereira, Negri, Andreia Francesli, Boldrin, Ana Carolina, Barcelos, Michela Dias, dos Santos, Thayza M. I. L., Milhim, Bruno H. G. A., Rocha, Leonardo Cecílio, Dourado, Fernanda Simões, dos Santos, Andresa Lopes, Ciconi, Victoria Bernardi, Patuto, Caio, Versiani, Alice Freitas, da Silva, Rafael Alves, de Oliveira Lobl, Edoardo Estevam, Hernandes, Victor Miranda, Zini, Nathalia, Pacca, Carolina Colombelli, Estofolete, Cássia Fernanda, Ferreira, Helena Lage, Rahal, Paula, Araújo, Jr, João Pessoa, Cohen, Jamie A., Kerr, Cliff C., Althouse, Benjamin M., Vasilakis, Nikos, and Nogueira, Mauricio Lacerda

Published
2022
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2. Influence of previous Zika virus infection on acute dengue episode

Author

Estofolete, Cassia F., primary, Versiani, Alice F., additional, Dourado, Fernanda S., additional, Milhim, Bruno H. G. A., additional, Pacca, Carolina C., additional, Silva, Gislaine C. D., additional, Zini, Nathalia, additional, Santos, Barbara F. dos, additional, Gandolfi, Flora A., additional, Mistrão, Natalia F. B., additional, Garcia, Pedro H. C., additional, Rocha, Rodrigo S., additional, Gehrke, Lee, additional, Bosch, Irene, additional, Marques, Rafael E., additional, Teixeira, Mauro M., additional, da Fonseca, Flavio G., additional, Vasilakis, Nikos, additional, and Nogueira, Maurício L., additional

Published
2023
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3. Performance of VIDAS® Diagnostic Tests for the Automated Detection of Dengue Virus NS1 Antigen and of Anti-Dengue Virus IgM and IgG Antibodies: A Multicentre, International Study

Author

Versiani, Alice F., primary, Kaboré, Antoinette, additional, Brossault, Ludovic, additional, Dromenq, Loïc, additional, dos Santos, Thayza M. I. L., additional, Milhim, Bruno H. G. A., additional, Estofolete, Cássia F., additional, Cissé, Assana, additional, Sorgho, Pegdwendé Abel, additional, Senot, Florence, additional, Tessonneau, Marie, additional, Diagbouga, Serge, additional, and Nogueira, Mauricio L., additional

Published
2023
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4. Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil

Author

Milhim, Bruno H. G. A., primary, da Rocha, Leonardo C., additional, Terzian, Ana C. B., additional, Mazaro, Carolina C. P., additional, Augusto, Marcos T., additional, Luchs, Adriana, additional, Zini, Nathalia, additional, Sacchetto, Livia, additional, dos Santos, Barbara F., additional, Garcia, Pedro H. C., additional, Rocha, Rodrigo S., additional, Liso, Elisabete, additional, Brienze, Vânia M. S., additional, da Silva, Gislaine C. D., additional, Vasilakis, Nikos, additional, Estofolete, Cássia F., additional, and Nogueira, Maurício L., additional

Published
2022
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5. Performance of VIDAS ® Diagnostic Tests for the Automated Detection of Dengue Virus NS1 Antigen and of Anti-Dengue Virus IgM and IgG Antibodies: A Multicentre, International Study.

Author

Versiani, Alice F., Kaboré, Antoinette, Brossault, Ludovic, Dromenq, Loïc, dos Santos, Thayza M. I. L., Milhim, Bruno H. G. A., Estofolete, Cássia F., Cissé, Assana, Sorgho, Pegdwendé Abel, Senot, Florence, Tessonneau, Marie, Diagbouga, Serge, and Nogueira, Mauricio L.

Subjects
DENGUE hemorrhagic fever, DENGUE viruses, IMMUNOGLOBULIN G, DIAGNOSIS methods, IMMUNOGLOBULINS, ANTIGENS
Abstract

Dengue is a serious mosquito-transmitted disease caused by the dengue virus (DENV). Rapid and reliable diagnosis of DENV infection is urgently needed in dengue-endemic regions. We describe here the performance evaluation of the CE-marked VIDAS® dengue immunoassays developed for the automated detection of DENV NS1 antigen and anti-DENV IgM and IgG antibodies. A multicenter concordance study was conducted in 1296 patients from dengue-endemic regions in Asia, Latin America, and Africa. VIDAS® dengue results were compared to those of competitor enzyme-linked immunosorbent assays (ELISA). The VIDAS® dengue assays showed high precision (CV ≤ 10.7%) and limited cross-reactivity (≤15.4%) with other infections. VIDAS® DENGUE NS1 Ag showed high positive and negative percent agreement (92.8% PPA and 91.7% NPA) in acute patients within 0–5 days of symptom onset. VIDAS® Anti-DENGUE IgM and IgG showed a moderate-to-high concordance with ELISA (74.8% to 90.6%) in post-acute and recovery patients. PPA was further improved in combined VIDAS® NS1/IgM (96.4% in 0–5 days acute patients) and IgM/IgG (91.9% in post-acute patients) tests. Altogether, the VIDAS® dengue NS1, IgM, and IgG assays performed well, either alone or in combination, and should be suitable for the accurate diagnosis of DENV infection in dengue-endemic regions. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Effects of SARS-CoV-2 P.1 introduction and the impact of COVID-19 vaccination on the epidemiological landscape of São José Do Rio Preto, Brazil

Author

Banho, Cecília Artico, primary, Sacchetto, Lívia, additional, Campos, Guilherme Rodrigues Fernandes, additional, Bittar, Cíntia, additional, Possebon, Fábio Sossai, additional, Ullmann, Leila Sabrina, additional, Marques, Beatriz de Carvalho, additional, da Silva, Gislaine Ceslestino Dutra, additional, Moraes, Marília Mazzi, additional, Parra, Maisa Carla Pereira, additional, Negri, Andreia Francesli, additional, Boldrin, Ana Carolina, additional, Barcelos, Michela Dias, additional, dos Santos, Thayza M. I. L., additional, Milhim, Bruno H. G. A., additional, da Rocha, Leonardo Cecílio, additional, Dourado, Fernanda Simões, additional, dos Santos, Andresa Lopes, additional, Ciconi, Victoria Bernardi, additional, Patuto, Caio, additional, Versiani, Alice Freitas, additional, da Silva, Rafael Alves, additional, Lobl, Edoardo Estevam de Oliveira, additional, Hernandes, Victor Miranda, additional, Zini, Nathalia, additional, Pacca, Carolina Colombelli, additional, Estofolete, Cássia Fernanda, additional, Ferreira, Helena Lage, additional, Rahal, Paula, additional, Araújo, João Pessoa, additional, Cohen, Jamie A., additional, Kerr, Cliff C., additional, Althouse, Benjamin M., additional, Vasilakis, Nikos, additional, and Nogueira, Mauricio Lacerda, additional

Published
2021
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7. Follow-up of a hospital cohort during the first 3,530 suspected cases of COVID-19 in Sao Jose do Rio Preto, Sao Paulo, Brazil

Author

Pacca, Carolina Colombelli, primary, Zini, Nathalia, additional, Versiani, Alice F., additional, de O. Lobl, Edoardo E., additional, Milhim, Bruno H. G. A., additional, Campos, Guilherme R. F., additional, Moraes, Marília M., additional, dos Santos, Thayza M.I.L, additional, Dourado, Fernanda S., additional, Marques, Beatriz C., additional, da Rocha, Leonardo C., additional, dos Santos, Andresa L, additional, da Silva, Gislaine C.D., additional, Ruiz, Leonardo G. P., additional, Nicesio, Raphael, additional, Queiroz, Flávia, additional, Reis, Andreia F. N., additional, da Silva, Natal S., additional, Nogueira, Maurício L., additional, and Estofolete, Cássia F., additional

Published
2021
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8. Validating and modeling the impact of high-frequency rapid antigen screening on COVID-19 spread and outcomes

Author

Nash, Beatrice, primary, Badea, Anthony, additional, Reddy, Ankita, additional, Bosch, Miguel, additional, Salcedo, Nol, additional, Gomez, Adam R., additional, Versiani, Alice, additional, Silva, Gislaine Celestino Dutra, additional, dos Santos, Thayza Maria Izabel Lopes, additional, Milhim, Bruno H. G. A., additional, Moraes, Marilia M, additional, Campos, Guilherme Rodrigues Fernandes, additional, Quieroz, Flávia, additional, Reis, Andreia Francesli Negri, additional, Nogueira, Mauricio L., additional, Naumova, Elena N., additional, Bosch, Irene, additional, and Herrera, Bobby Brooke, additional

Published
2020
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11. Diabetes as risk factor to severity of dengue in naïve patients.

Author

Dos Santos BF, Gandolfi FA, Milhim BHGA, Dourado FS, Silva GCD, Zini N, Gratão VHR, Mariani MP, Abbas TN, Garcia PHC, Rocha RS, Vasilakis N, Nogueira ML, and Estofolete CF

Abstract

Background: Dengue cases can progress to severe ant life-threating forms particularly in subsequent heterologous infections. However, recent studies had explored additional risk factors, including underlying health conditions, even in individuals without prior exposure to dengue, notably, in patients with endothelial dysfunction and chronic inflammation. This study examines the link between diabetes and the development of severe dengue disease in dengue-naive patients during the 2019 dengue outbreak in São Jose do Rio Preto, Brazil., Methodology: We enrolled 529 laboratory-confirmed dengue cases, identified through DENV RT-PCR or NS1 antigen assays in a hospital cohort of acute febrile illness. Subsequently, we investigated the presence of anti-dengue and anti-Zika IgG antibodies. Samples testing positive for Zika were excluded from the analyses. Two groups were analyzed: naïve (DV-), and dengue history (DV+)., Results: Initially, presence of diabetes and kidney disease, as well as being dengue-naive, were associated with a higher frequency of severe and potentially severe clinical outcomes. Multivariate analysis identified diabetes as a risk factor, while the presence of anti-dengue antibodies was considered protective. Analysis of dengue naïve samples, highlighted diabetes as an independent risk factor to severe forms of dengue disease. In DV+ patients, no condition was highlighted as a risk factor by univariate analysis or multivariate analysis., Conclusions: We investigated and confirmed diabetes as a risk factor for severe dengue disease in individuals without prior dengue or Zika exposure. Our conclusions raise significant concerns given diabetes' ever increasing global prevalence and its potential impact on patients with or previous dengue exposure., Competing Interests: Competing interests The authors declare no competing interests.

Published
2024
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