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1. Relationship between clinical congestion and worsening renal function after intravenous initiation of furosemide in patients with acute heart failure

Author

Espinosa, Begoña, Llauger, Lluís, Gil, Víctor, Escoda, Rosa, Jacob, Javier, Aguirre, Alfons, Mojarro, Enrique Martín, Tost, Josep, Alquézar-Arbé, Aitor, López-Grima, María Luisa, Millán, Javier, Massó, Marta, Cuquerella, Guillem Suñén, Pagán, Francesc, Núñez, Julio, Dauw, Jeroen, Müllens, Wilfried, Llorens, Pere, and Miró, Òscar

Published
2024
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3. Digoxin initiation after an acute heart failure episode and its association with post-discharge outcomes: an international multicenter analysis

Author

Miró, Òscar, Mojarro, Enrique Martín, Huré, Gabrielle, Llorens, Pere, Gil, Víctor, Alquézar-Arbé, Aitor, Bibiano, Carlos, González, Nayra Cabrera, Massó, Marta, Strebel, Ivo, Espinosa, Begoña, Masó, Silvia Mínguez, Wussler, Desiree, Shrestha, Samyut, Lopez-Ayala, Pedro, Jacob, Javier, Millán, Javier, Andueza, Juan Antonio, Alonso, Héctor, Pàmies, Silvia Larrondo, Cerdà, Jaume Farré, Martínez, Celia Planco, Herrero, Pablo, Frank Peacock, W., and Mueller, Christian

Published
2024
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4. Impact of chronic renin-angiotensin-aldosterone inhibitors on short-term outcomes in patients with acute heart failure presenting to the emergency department. A propensity-matched analysis EAHFE cohort

Author

Fuentes, Marta, Davila, Aitor, del Amo, Sonia, Alonso, Héctor, Pérez-Llantada, Enrique, Martín-Sánchez, Francisco Javier, Miró, Òscar, Gil, Víctor, Escoda, Rosa, Sánchez, Carolina, Repullo, Daniel, Masso, Marta, Millán, Javier, Serrano, Leticia, Pavón, José, González, Nayra Cabrera, Rodríguez, Rafael Calvo, Reyes, Juan Antonio Vega, López-Grima, María Luisa, Valero, Amparo, Juan, María Ángeles, Aguirre, Alfons, Masó, Silvia Mínguez, Pérez, Virginia Fernández-Távora, Mecina, Ana Belén, Tost, Josep, Ramón, Susana Sánchez, Rodríguez, Virginia Carbajosa, Piñera, Pascual, Nicolás, José Andrés Sánchez, Aragüés, Paula Lázaro, Garate, Raquel Torres, Rodríguez, Esther Álvarez, Arias, Pilar Paz, Alquézar-Arbé, Aitor, Herrera, Sergio, Carrete, Carlos José Romero, Jacob, Javier, Roset, Alex, Cabello, Irene, Haro, Antonio, Fuentes, Lidia, Richard, Fernando, Fernández, Elisa, Diez, María Pilar López, Puente, Pablo Herrero, Álvarez, Joaquín Vázquez, García, Belén Prieto, Fernández, Alejandra Fernández, Ramos, Belén Álvarez, Miranda, Natalia Fernández, Llorens, Pere, Espinosa, Begoña, Guzmán, Sergio, Jara, Gema, Felipe, Alba, Gil, Adriana, Andueza, Juan Antonio, Romero, Rodolfo, López, Mariella Luengo, Domínguez, Gema, Ruíz, Martín, Arriaga, Beatriz Amores, Bergua, Beatriz Sierra, Mojarro, Enrique Martín, Jiménez, Lidia Cuevas, Bécquer, Lisette Travería, Burillo, Guillermo, García, Lluís Llauger, de la Torre, María De Los Ángeles González, Jiménez, Carmen Esmeralda Romero, Ferrer, Ester Soy, Múñoz, María Adroher, Lucas-Imbernón, Francisco Javier, Gaya, Rut, Bibiano, Carlos, Mir, María, Rodríguez, Beatriz, Martín, Monika Vicente, Adrada, Esther Rodríguez, Baldrich, Eva Domingo, Carvajal, Marianela Guzmán, Fortuny, María José, García, Yelenis Gómez, Coronill, Verónica de las Nieves Segura, Esquivias, Marco Antonio, del Carmen Martínez Picón, María, Callejas, Marina Borox, García, Rocío Moyano, Rodríguez, Pablo, Cuevas, María Martínez, Noceda, José, Blasco, Santiago Harris, Romero, Marta, Valladares, Jordi Estopá, González, Natalia Ramos, Lorenzo, Rocio, Valencia, Juan Bautista, Bembibre, Lorena, Guerrero, Inés Fernández, Garrido, José Manuel, Pedret, Oriol Aguiló, Haro, Antoni, Rosselló, Xavier, Herrero, Pablo, Llauger, Lluis, Burillo-Putze, Guillermo, López-Díez, María Pilar, Martín-Mojarro, Enrique, Garrido, Jose Manuel, Domingo, Eva, and Calvo-Rodríguez, Rafael

Published
2025
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5. Genetics of randomly bred cats support the cradle of cat domestication being in the Near East

Author

Nilson, Sara M, Gandolfi, Barbara, Grahn, Robert A, Kurushima, Jennifer D, Lipinski, Monika J, Randi, Ettore, Waly, Nashwa E, Driscoll, Carlos, Murua Escobar, Hugo, Schuster, Rolf K, Maruyama, Soichi, Labarthe, Norma, Chomel, Bruno B, Ghosh, Sankar Kumar, Ozpinar, Haydar, Rah, Hyung-Chul, Millán, Javier, Mendes-de-Almeida, Flavya, Levy, Julie K, Heitz, Elke, Scherk, Margie A, Alves, Paulo C, Decker, Jared E, and Lyons, Leslie A

Subjects
Biological Sciences, Genetics, Animals, Cats, Domestication, Genotype, Microsatellite Repeats, Middle East, Evolutionary Biology, Evolutionary biology
Abstract

Cat domestication likely initiated as a symbiotic relationship between wildcats (Felis silvestris subspecies) and the peoples of developing agrarian societies in the Fertile Crescent. As humans transitioned from hunter-gatherers to farmers ~12,000 years ago, bold wildcats likely capitalized on increased prey density (i.e., rodents). Humans benefited from the cats' predation on these vermin. To refine the site(s) of cat domestication, over 1000 random-bred cats of primarily Eurasian descent were genotyped for single-nucleotide variants and short tandem repeats. The overall cat population structure suggested a single worldwide population with significant isolation by the distance of peripheral subpopulations. The cat population heterozygosity decreased as genetic distance from the proposed cat progenitor's (F.s. lybica) natural habitat increased. Domestic cat origins are focused in the eastern Mediterranean Basin, spreading to nearby islands, and southernly via the Levantine coast into the Nile Valley. Cat population diversity supports the migration patterns of humans and other symbiotic species.

Published
2022

6. Características clínicas, manejo en urgencias y mortalidad de los episodios de insuficiencia cardiaca aguda en pacientes con enfermedad pulmonar obstructiva crónica

Author

Fuentes, Marta, Dávila, Aitor, del Amo, Sonia, Alonso, Héctor, Pérez-Llantada, Enrique, Martín-Sánchez, Francisco Javier, Miró, Òscar, Gil, Víctor, Escoda, Rosa, Sánchez, Carolina, Repullo, Daniel, Massó, Marta, Millán, Javier, Serrano, Leticia, Pavón, José, González, Nayra Cabrera, Rodríguez, Rafael Calvo, Reyes, Juan Antonio Vega, López-Grima, María Luisa, Valero, Amparo, Juan, María Ángeles, Aguirre, Alfons, Masó, Silvia Mínguez, Pérez, Virginia Fernández-Távora, Mecina, Ana Belén, Tost, Josep, Ramón, Susana Sánchez, Rodríguez, Virginia Carbajosa, Piñera, Pascual, Nicolás, José Andrés Sánchez, Aragüés, Paula Lázaro, Garate, Raquel Torres, Rodríguez, Esther Álvarez, Arias, Pilar Paz, Alquézar-Arbé, Aitor, Herrera, Sergio, Carrete, Carlos José Romero, Jacob, Javier, Roset, Alex, Cabello, Irene, Haro, Antonio, Fuentes, Lidia, Richard, Fernando, Fernández, Elisa, Diez, María Pilar López, Puente, Pablo Herrero, Álvarez, Joaquín Vázquez, García, Belén Prieto, Fernández, Alejandra Fernández, Ramos, Belén Álvarez, Miranda, Natalia Fernández, Llorens, Pere, Espinosa, Begoña, Guzmán, Sergio, Jara, Gema, Felipe, Alba, Gil, Adriana, Andueza, Juan Antonio, Romero, Rodolfo, López, Mariella Luengo, Domínguez, Gema, Ruíz, Martín, Arriaga, Beatriz Amores, Bergua, Beatriz Sierra, Mojarro, Enrique Martín, Jiménez, Lidia Cuevas, Bécquer, Lisette Travería, Burillo, Guillermo, García, Lluís Llauger, Torre, María de los Ángeles González de la, Jiménez, Carmen Esmeralda Romero, Ferrer, Ester Soy, Múñoz, María Adroher, Garrido, José Manuel, Lucas-Imbernón, Francisco Javier, Gaya, Rut, Bibiano, Carlos, Mir, María, Rodríguez, Beatriz, Martín, Monika Vicente, Adrada, Esther Rodríguez, Baldrich, Eva Domingo, Carvajal, Marianela Guzmán, Fortuny, María José, García, Yelenis Gómez, Coronill, Verónica de las Nieves Segura, Esquivias, Marco Antonio, Picón, María del Carmen Martínez, Callejas, Marina Borox, García, Rocío Moyano, Rodríguez, Pablo, Cuevas, María Martínez, Noceda, José, Blasco, Santiago Harris, Romero, Marta, Pedret, Oriol Aguiló, Valladares, Jordi Estopá, González, Natalia Ramos, Lorenzo, Rocio, Valencia, Juan Bautista, Bembibre, Lorena, Guerrero, Inés Fernández, Ivars, N., Llorens, P., Alquézar, A., Jacob, J., Rodríguez, B., Guzmán, M., Serrano Lázaro, L., Martínez Picón, M.C., Cuevas Jiménez, L., and Miró, Ò.

Published
2024
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10. Combining loop with thiazide diuretics in patients discharged home after a heart failure decompensation: Association with 30-day outcomes

Author

Fuentes, Marta, Davila, Aitor, del Amo, Sonia, Alonso, Héctor, Pérez-Llantada, Enrique, Martín-Sánchez, Francisco Javier, Miró, Òscar, Gil, Víctor, Escoda, Rosa, Sánchez, Carolina, Repullo, Daniel, Masso, Marta, Millán, Javier, Serrano, Leticia, Pavón, José, González, Nayra Cabrera, Rodríguez, Rafael Calvo, Reyes, Juan Antonio Vega, López-Grima, María Luisa, Valero, Amparo, Juan, María Ángeles, Aguirre, Alfons, Masó, Silvia Mínguez, Alonso, María Isabel, Mecina, Ana Belén, Tost, Josep, Ramón, Susana Sánchez, Rodríguez, Virginia Carbajosa, Piñera, Pascual, Nicolás, José Andrés Sánchez, Aragüés, Paula Lázaro, Garate, Raquel Torres, Rodríguez, Esther Álvarez, Arias, Pilar Paz, Alquézar-Arbé, Aitor, Herrera, Sergio, Carrete, Carlos José Romero, Jacob, Javier, Roset, Alex, Cabello, Irene, Haro, Antonio, Richard, Fernando, Fernández, Elisa, Diez, María Pilar López, Puente, Pablo Herrero, Álvarez, Joaquín Vázquez, García, Belén Prieto, Fernández, Alejandra Fernández, Ramos, Belén Álvarez, Miranda, Natalia Fernández, Llorens, Pere, Espinosa, Begoña, Jara, Gema, Felipe, Alba, Andueza, Juan Antonio, Romero, Rodolfo, López, Mariella Luengo, Domínguez, Gema, Ruíz, Martín, Arriaga, Beatriz Amores, Bergua, Beatriz Sierra, Mojarro, Enrique Martín, Jiménez, Lidia Cuevas, Bécquer, Lisette Travería, Burillo, Guillermo, García, Lluís Llauger, Urbano, Carmen Agüera, de los Ángeles, María, de la Torre, González, Jiménez, Carmen Esmeralda Romero, Ferrer, Ester Soy, Múñoz, María Adroher, Garrido, José Manuel, Lucas-Imbernón, Francisco Javier, Gaya, Rut, Bibiano, Carlos, Mir, María, Rodríguez, Beatriz, Martín, Monika Vicente, Adrada, Esther Rodríguez, Domingo, Eva, Carvajal, Marianela Guzmán, Fortuny, María José, García, Yelenis Gómez, de las Nieves Segura Coronill, Verónica, Esquivias, Marco Antonio, García, Rocío Moyano, Rodríguez, Pablo, Noceda, José, Blasco, Santiago Harris, Romero, Marta, Lorenzo, Miguel, Núñez, Gonzalo, de la Espriella, Rafael, Villar, Sandra, Santas, Enrique, Miñana, Gema, Bodí, Vicent, Sanchis, Juan, Núñez, Julio, Bautista, Prado Salamanca, Hueso, Rocío Ruiz, Domingo, Soraya, Núñez, Mª Victoria, Olmedo, Jesús, Vázquez, Carmen, López, Juan Bosco, Peinado, Alejandro, Montes, Juan Antonio, Díez-Manglano, Jesús, Rodés, Pablo Martínez, Garcés, Vanesa, Rubio, Jorge, Rodríguez, José M Fernández, Curto, Adrián Argüelles, Murphy, Orla Torrallardona, Manso, Meritxell Gavà, Martel, Alicia Conde, García, José Mª, González, Sonia, Dávila, Melitón F, Hernández, Rubén, Gudiño, Diego José, Mendoza, Humberto, Carrera, Margarita, Trullàs, Joan Carles, Epelde, Francisco, Biosca, Anna Sánchez, Becerra, Raquel, Gil, Mercè, Massi, Paulina Ivanova, Chivite, David, Formiga, Francesc, Núñez, Raquel, Pacho, Cristina, Contra, Anna, Ceresuela, Luis, Morales, José Luís, Pla, Xavi, López, Gabriel, Blázquez, Julio, Reboiro, Manuel Lorenzo López, Castro, José López, Asenjo, María, de Peralta, Paula, Llàcer, Pau, Manzano, Luis, Ortega, Raúl Antonio Ruiz, Vázquez, Miguel Ángel, Soler, Llanos, Mesado, Daniel, Casado, Jesús, Abad, Daniel, Ballesta, Ana Isabel Peláez, Rodríguez, Elena Morcillo, Lopez-Ayala, Pedro, Llauger, Lluís, Mollar, Anna, Garcés-Horna, Vanesa, Martínez-Nadal, Gemma, and Mueller, Christian

Published
2024
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11. Coxiella burnetii Infection in Livestock, Pets, Wildlife, and Ticks in Latin America and the Caribbean: a Comprehensive Review of the Literature

Author

Epelboin, Loïc, De Souza Ribeiro Mioni, Mateus, Couesnon, Aurelie, Saout, Mona, Guilloton, Edith, Omar, Salma, De Santi, Vincent Pommier, Davoust, Bernard, Marié, Jean Lou, Lavergne, Anne, Donato, Damien, Guterres, Alexandro, Rabier, Sebastien, Destoop, Justin, Djossou, Felix, Baudrimont, Xavier, Roch, Antoine, Cicuttin, Gabriel Leonardo, Rozental, Tatiana, Nacher, Mathieu, Millán, Javier, De Lemos, Elba R. Sampaio, Fernandes, Jorlan, Duron, Olivier, De Thoisy, Benoit, and Rousset, Elodie

Published
2023
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14. Emergency department direct discharge compared to short-stay unit admission for selected patients with acute heart failure: analysis of short-term outcomes

Author

Sánchez-Marcos, Carolina, Jacob, Javier, Llorens, Pere, López-Díez, María Pilar, Millán, Javier, Martín-Sánchez, Francisco Javier, Tost, Josep, Aguirre, Alfons, Juan, María Ángeles, Garrido, José Manuel, Rodríguez, Rafael Calvo, Pérez-Llantada, Enrique, Díaz, Elena, Sánchez-Nicolás, José Andrés, Mir, María, Rodríguez-Adrada, Esther, Herrero, Pablo, Gil, Víctor, Roset, Alex, Peacock, Frank, and Miró, Òscar

Published
2023
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18. Frequency, Risk Factors, Clinical Characteristics, and Outcomes of Spontaneous Pneumothorax in Patients With Coronavirus Disease 2019: A Case-Control, Emergency Medicine-Based Multicenter Study

Author

Miró, Òscar, Jiménez, Sònia, González del Castillo, Juan, Martín-Sánchez, Francisco Javier, Llorens, Pere, Burillo-Putze, Guillermo, Martín, Alfonso, Salmerón, Pascual Piñera, García Lamberechts, E. Jorge, Jacob, Javier, Alquézar-Arbé, Aitor, López Grima, María Luisa, Juan Gómez, María Ángeles, Millán, Javier, Lázaro, Leticia Serrano, Peña, Bárbara, Román, Francisco, Noceda, José, Cano Cano, María José, Serra, Rosa Sorando, José Fortuny Bayarri, María, José Salvador Suárez, Francisco, Tejera, Matilde González, Herrera, Liced Aguilar, Caballero Mateos, Ana María, Meléndez, Napoleón, Albero, Patricia Borrás, Jiménez, Blas, Río, Rigoberto del, García, Carles Pérez, Amador, Pilar Sánchez, Brasó Aznar, José Vicente, Ruiz López, José Luis, Ponce, María Carmen, Fernández, Elena Díaz, Martínez, Laura Ejarque, de Reynoso Rodríguez, Marisa, Gómez, Ana Peiró, Bellver, Elena Gonzalo, Rizzi, Miguel, Suarez, Carla Cabrera, Argilag, Laura Balcells, Cardozo, Carlos, Roset-Rigat, Alejandro, Haro-Bosch, Antonio, Rovira, Marta Alujas, Arbaizar, Pepe Ferrer, Tost, Josep, Lorenzo, Isabel Cirera, Masó, Silvia Mínguez, Palau, Anna, Tur, Ruth Gaya, Muñoz, Maria Adroher, Ferrer, Ester Soy, García, Lluís Llauger, Alarcón Jiménez, Brigitte Silvana, Quesada, Silvia Flores, Huerta, Arturo, Fragiel, Marcos, Álvarez, Susana Martínez, Martínez Virto, Ana María, Galán, Carmen del Arco, Jiménez, Guillermo Fernández, Rodríguez, Esther Álvarez, Villa, Teresa Agudo, Venegas de L’Hotellerie, María José, Cabezas, Verónica Prieto, Mocanu, Catalina, Nieto, Patricia Gantes, Alonso, Marta Álvarez, Marco, Cristina Latorre, Gaforio, Alicia Fuente, Galán, Beatriz Honrado, Martín, Sara Gayoso, Somohano, Frida Vallejo, Laguna, Nieves López, Panadero, Raquel Piñero, Fuentes de Frutos, Marta, Castillo, Cristina Gil, Castañeda, Ana Barrientos, Escudero, Susana Garcia, López Díez, María Pilar, Oliva Ramos, Jose Ramón, Herrero, Daniel Serrano, Flórez, Rosa Castellanos, Chaib, Fadh Beddar, Mohamedi Abdelkader, Ikram Samira, Tornero, Ana Pérez, Chia, Alberto Núñez, Pérez, Esther Maldonado, Martín, Verónica Rodríguez, García Soto, Ana Belen, Padial, Elisa Delgado, García, Jorge Pedraza, Fernández de Simón Almela, Amparo, López, Ricardo Calvo, José López Díaz, Juan, Maza Vera, María Teresa, Calveiro, Raquel Rodríguez, Lucas-Galán, Francisco Javier, Moreno, María Ruipérez, Martínez, Félix González, Olmeda, Diana Moya, Juárez, Ricardo, Rodríguez, Marcos Expósito, Fernández Rodríguez, José Francisco, Monzo, José Pavón, González, Nayra Cabrera, Velarde Herrera, Desiré María, Martínez Bautista, Beatriz María, Niembro Valdés, Ana Patricia, Álvarez, Lorena Arboleya, Motto, Eva Quero, García, Nuria Tomas, Sánchez Nicolás, José Andrés, Aragües, Paula Lázaro, Ruiz de Lobera, Noemí, Ferreras Amez, José María, Piñera, Pascual, García-Lamberetchs, Eric Jorge, Mòdol, Josep Maria, López-Díez, María Pilar, Guardiola, Josep Maria, Lucas Imbernón, Francisco Javier, Aguirre Tejedo, Alfons, García García, Ángel, Ruiz Grinspan, Martín, and Llopis Roca, Ferran

Published
2021
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19. Association of intravenous digoxin use in acute heart failure with rapid atrial fibrillation and short-term mortality according to patient age, renal function, and serum potassium.

Author

Miró, Òscar, Mojarro, Enrique Martín, Lopez-Ayala, Pedro, Llorens, Pere, Gil, Víctor, Alquézar-Arbé, Aitor, Bibiano, Carlos, Pavón, José, Massó, Marta, Strebel, Ivo, Espinosa, Begoña, Masó, Silvia Mínguez, Jacob, Javier, Millán, Javier, Andueza, Juan Antonio, Alonso, Héctor, Herrero-Puente, Pablo, and Mueller, Christian

Published
2024
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25. High diversity, novel genotypes, and vertical transmission of hemotropic Mycoplasma in micromammals

Author

Ministerio de Ciencia e Innovación (España), Gobierno de Aragón, Martínez-Padilla, Jesús [0000-0003-2956-5163], Millán, Javier, Martín-Maldonado, Bárbara, Rodríguez-Pastor, Ruth, Martínez-Padilla, Jesús, Esperón, Fernando, Ministerio de Ciencia e Innovación (España), Gobierno de Aragón, Martínez-Padilla, Jesús [0000-0003-2956-5163], Millán, Javier, Martín-Maldonado, Bárbara, Rodríguez-Pastor, Ruth, Martínez-Padilla, Jesús, and Esperón, Fernando

Abstract

Hemotropic mycoplasmas (hemoplasmas) are emerging zoonotic pathogens. Micromammals have received little attention as hosts for hemoplasmas despite their ubiquitous presence, high population abundances, and close association with humans. A PCR protocol targeting a fragment of the 16 S rRNA gene and direct sequencing in blood samples of 189 adult specimens and 35 fetuses belonging to three species of Eulipotyphla (shrews) and seven species of Rodentia, captured in three ecologically diverse habitats in North-Eastern Spain (Steppe, High Mountain, Mediterranean) yielded and occurrence of 26%, including 36% of 39 shrews and 23% of 150 rodents. Sequencing revealed the presence of 14 nucleotide sequence types (ntST) among the 56 readable sequences. In general, each ntST was associated with a given host species, although in some cases, the same ntST was sequenced in different species (chiefly rodents). Most ntST were closely related to rodent and/or bat hemoplasmas, but one was identical with Mycoplasma haemocanis/haemofelis, and others can be considered novel genotypes. High sequence diversity was detected in rodents, whereas in the white-toothed shrew (Crocidura russula), 9/11 sequences from two distant areas were identical. Phylogenetic and network analyses classified our sequences in different clades including hemoplasmas of rodents, carnivores, bats, and humans. Twelve of the fetuses (34.2%) of 9/12 litters (75.0%) of shrews and rodents were hemoplasma-positive, indicating frequent vertical transmission. Our study contributes to expanding our knowledge about the distribution, diversity, and transmission of hemoplasmas.

Published
2024

26. Leptospirosis in Wild and Domestic Carnivores in Natural Areas in Andalusia, Spain

Author

Millán, Javier, Candela, Mónica G., López-Bao, José Vicente, Pereira, Marian, Jiménez Martínez, María De Los Ángeles, León-Vizcaíno, Luis, Millán, Javier, Candela, Mónica G., López-Bao, José Vicente, Pereira, Marian, Jiménez Martínez, María De Los Ángeles, and León-Vizcaíno, Luis

Abstract

Leptospirosis is a zoonosis that affects humans, domestic animals, and wildlife. Carnivores are at the top of the feeding chain, thus being exposed to pathogens through their preys. From June 2004 to April 2007, we analyzed for evidences of contact with 14 serovars of Leptospira interrogans Sensu Lato serum (analyzed by indirect Microscopic Agglutination Test) and urine or kidney samples (analyzed by microscopic observation, immunostaining and culture) collected from 201 wild and domestic carnivores, including 26 free-living Iberian lynx (Lynx pardinus), 33 red foxes (Vulpes vulpes), 33 Egyptian mongooses (Herpestes ichneumon), 25 common genets (Genetta genetta), two Eurasian badgers (Meles meles) and one Eurasian otter (Lutra lutra), and 53 free-roaming cats and 28 rural dogs in protected areas in Andalusia (southern Spain). Twenty-three percent of the animals presented evidences of contact, being the prevalence similar among wild (23.5%) and domestic species (22.2%). Contact with Lesptospira was detected in all the species but the otter. Prevalence was: lynx (11% by bacteriological detection, 32% by serology), fox (0%, 47%), mongoose (5%, 20%), genet (0%, 12%), badger (0%, 50%), cat (20%, 14%), dog (only serology: 36%). Serovar Icterohemorragiae accounted for 2/3 of the cases. Serovar Canicola was detected in half of the positive dogs and one lynx. Other serovars detected were Ballum, Sejroë, and Australis. No macroscopic lesions were observed in necropsied animals that showed evidence of contact with the agent, although histopathologic lesions (chiefly chronic interstitial nephritis) were observed in 7 out of the 11 microscopically analyzed individuals. Thus, L. interrogans may cause previously unrecorded disease in wild carnivores in Spain. Wild and free-roaming carnivores may not act as reservoir of L. interrogans but as a dead-end hosts, though the dog may act as reservoir of serovar Canicola. Carnivores are apparently good sentinels for the epidemiological mo, Depto. de Medicina y Cirugía Animal, Fac. de Veterinaria, TRUE, pub

Published
2024

35. Radiographic Study of Transcrestal Sinus Floor Elevation Using Osseodensification Technique with Graft Material: A Pilot Study.

Author

Sulyhan-Sulyhan, Khrystyna, Barberá-Millán, Javier, Larrazábal-Morón, Carolina, Espinosa-Giménez, Julián, and Gómez-Adrián, María Dolores

Subjects
*CONE beam computed tomography, *SINUS augmentation, *MAXILLARY sinus, *PILOT projects, *ENDOSSEOUS dental implants, *BONE grafting, *OSSEOINTEGRATED dental implants
Abstract

This pilot study aimed to evaluate the level of implant success after transcrestal sinus floor elevation (tSFE) using the osseodensification technique (OD) combined with beta-tricalcium phosphate (β-TCP) by analyzing clinical and radiographic results. Moreover, the increase in bone height was analyzed immediately after surgery, 3 months after, and before loading by taking standardized radiographic measurements. Thirteen patients, four males and nine females, with a mean age of 54.69 ± 5.86 years, requiring the placement of one implant in the upper posterior maxilla, with a residual bone height of <8 mm and a minimum bone width of 5 mm, participated in the study. The bone gain data was obtained using cone-beam computed tomography (CBCT) immediately after surgery and twelve months after the placement. The correlation between initial and final bone height with implant stability was also assessed. The results were analyzed using SPSS 23 software (p < 0.05). The results of the study indicated a 100% implant success rate after a follow-up period of twelve months. Preoperative main bone height was 5.70 ± 0.95 mm. The osseodensification technique allowed a significant increase of 6.65 ± 1.06 mm immediately after surgery. After a twelve-month follow-up, a graft material contraction of 0.90 ± 0.49 mm was observed. No correlation was observed between the bone height at the different times of the study and the primary stability of the implant. Considering the limitations of the size sample of this study, the osseodensification technique used for transcrestal sinus lift with the additional bone graft material (β-TCP) may provide a predictable elevation of the maxillary sinus floor, allowing simultaneous implant insertion with adequate stability irrespective of bone height limitations. [ABSTRACT FROM AUTHOR]

Published
2024
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36. EPIZOOTIOLOGY AND PATHOLOGY OF SARCOPTIC MANGE IN TWO SPECIES OF FOX (LYCALOPEX SPP.) IN HUMAN-DOMINATED LANDSCAPES OF CENTRAL CHILE.

Author

Millán, Javier, Cevidanes, Aitor, Cataldo, Sophia Di, Hernández, Claudia, Peñaloza-Madrid, Diego, Sallabery-Pincheira, Nicole, Terio, Karen, and Casais, Rosa

Abstract

Sarcoptic mange caused by Sarcoptes scabiei can have catastrophic consequences for wildlife. We inspected 122 Andean foxes (Lycalopex culpaeus), collected by active (n=66) or passive (n=56) surveillance, and 28 South American gray foxes (Lycalopex griseus; all from passive surveillance) for mange in Chile (2015–19). In Andean foxes, gross lesions of mange were diagnosed in 24% of passively and 9% of actively collected foxes, although observed prevalences might be underestimated. Seroprevalence was 37 and 18%, respectively, indicating that some individuals recovered from infection or were developing the disease. No differences were found between age and sex groups. Comparing data from passive surveillance, occurrence of gross lesions was lower in gray foxes (5%). Body condition was significantly better in Andean foxes without lesions than in diseased foxes, which had significantly lower albumin concentrations than healthy individuals. Among the 12 foxes with gross lesions, four, six and two individuals were categorized as having type I, type II, and type III lesions, respectively, based on clinical severity. Histologic severity correlated with gross lesions and included irregular epidermal hyperplasia with hyperkeratosis, which was marked in type II and III infections. Conventional PCR targeting of the cox1 gene fragment revealed four nucleotide sequence types, showing 99–100% identity among them and between 99% and 100% identity with previously published sequences of S. scabiei. A significant association between the occurrence of mange in foxes and distance to the nearest house was found. We speculate that diseased foxes tended to approach human settlements, perhaps in search of food. Visual inspection of 211 rural dogs from the study area did not reveal gross mange lesions in any animal. Sarcoptic mange is enzootic in the Andean fox in the study area and should be considered in the management of the species. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Stroke Prophylaxis in Atrial Fibrillation: Searching for Management Improvement Opportunities in the Emergency Department: The HERMES-AF Study

Author

Suero, Coral, Román, Emilio, Heredia, Francisca, Sagarra, Ana M<ce:sup loc='post">a</ce:sup>, Estella, Ángel, Brun, Francisco Manuel, Simón, Elías, Torres, José Manuel, Lopera, Elisa, Soriano, Fuensanta, Santamarina, Fernando, Sánchez, Juan, Feixas, Matilde F., Hierro, F. Javier, Santos, José M<ce:sup loc='post">a</ce:sup>, Perea, Álvaro F., Tembury, Francisco, Rizo, Macarena, Ramirez, Adolfo, Sindiones, Rafael, Moya, Francisco, Fernández, Amparo, Ruiz, Francisco, Garrido, José Manuel, Almagro, Enrique, Povar, Javier, Aldea, Elisa, Rivas, Miguel, Galve, Fernando, Muñoz, Manuel, García, Juan Alberto, Cals, Pedro, Gutierrez, Ana, García-Castrillo, Luis, Rodriguez, María José, Richard, Fernando, López, Beatriz, Lapuerta, Luis, Toranzo, Tomás, Zapico, Nicanor, Sánchez, Susana, Melendre, Ana, Aguilar, José, del Mar Sousa, M<ce:sup loc='post">a</ce:sup>, Lopez, Alberto, Montero, Luis, Rodriguez-Bobada, Raimundo, Perales, Ramón, Roldán, Rosa, Fuenzalida, Carolina, Trejo, Olga M<ce:sup loc='post">a</ce:sup>, Aguirre, Alfons, Soriano, Teresa, Vila, Mireia, Fornet, Lluis, Casarramona, Francisco, Sánchez, M<ce:sup loc='post">a</ce:sup> Isabel, Font, Julio, Espinach, Joan, Almirall, Mercè, Danés, Joaquin, Herrera, Alvaro, Flores, Silvia, Jammoul, Ali, Vicente, José, Campos, M<ce:sup loc='post">a</ce:sup> Isabel, Colomina, Rafael, Escámez, Joaquin, Arcos, Begoña, Navarro, M<ce:sup loc='post">a</ce:sup> Carmen, Millán, Javier, Noceda, Jose Javier, Rubini, Salvador, Rubini, Ricardo, Carbajosa, José, Díaz, M<ce:sup loc='post">a</ce:sup> Elena, Navarro, Francisco J., González, Matilde, Mateo, Adelaida, Gisbert, Cristina, Navarro, Francisco, Varona, Mercedes, Cancio, Manuel, López, Ignacio, Muñoz, Francisco David, García, M<ce:sup loc='post">a</ce:sup> Teresa, Lamas, Pablo, Amador, Luis, Calvo, Ricardo, Seijas, Carmen, Selloso, M<ce:sup loc='post">a</ce:sup> C., García, Manuel, Aramburu, Francisco José, Leciñena, M<ce:sup loc='post">a</ce:sup> A., Planas, Alex, Ayala, Ignacio, Alonso, Jose Emilio, Gutiérrez, Benito, Marco, Pedro, Rodríguez, Belén, del Arco, Carmen, Parra, Juan Manuel, González, Juan, Diaz, Luis, Álvarez, Oscar, Andueza, Juan, García, Joaquin, Jiménez, Gregorio, Martín, Alfonso, Malagón, Francisco, Ruizy, Manuel, Mora, Esther, Torres, Juan, Canora, Jesús, Bibiano, Carlos, Piñera, Pascual, Retuerto, Enrique, Melgares, Jose M<ce:sup loc='post">a</ce:sup>, Cruzado, Jesús, Escudero, Carmen, Hernández, Ángel, Jiménez, Eduardo, López, Jose, Coll-Vinent, Blanca, and Montull, Eugeni

Published
2015
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46. Epidemiology and molecular characterization of Carnivore protoparvovirus-1 infection in the wild felid Leopardus guigna in Chile

Author

Comisión Nacional de Investigación Científica y Tecnológica (Chile), Fondo Nacional de Desarrollo Científico y Tecnológico (Chile), National Geographic Society, Morris Animal Foundation, Sacristán, Irene [0000-0002-4169-4884], Esperón, Fernando [0000-0002-8810-5071], Pérez, Rubén [0000-0003-4961-4743], García, Sebastián [0000-0001-6048-1545], López, María José [0000-0002-9646-6483], Hidalgo-Hermoso, Ezequiel [0000-0002-1291-514X], Terio, Karen A [0000-0003-4924-5503], Millán, Javier [0000-0001-5608-781X], Poulin, Elie [0000-0001-7736-0969], Napolitano, Constanza [0000-0002-7081-6975], Sacristán, Irene, Esperón, Fernando, Pérez, Rubén, Acuña, Francisca, Aguilar, Emilio, García, Sebastián, López, María José, Neves, Elena, Cabello-Stom, Javier, Hidalgo-Hermoso, Ezequiel, Terio, Karen A, Millán, Javier, Poulin, Elie, Napolitano, Constanza, Comisión Nacional de Investigación Científica y Tecnológica (Chile), Fondo Nacional de Desarrollo Científico y Tecnológico (Chile), National Geographic Society, Morris Animal Foundation, Sacristán, Irene [0000-0002-4169-4884], Esperón, Fernando [0000-0002-8810-5071], Pérez, Rubén [0000-0003-4961-4743], García, Sebastián [0000-0001-6048-1545], López, María José [0000-0002-9646-6483], Hidalgo-Hermoso, Ezequiel [0000-0002-1291-514X], Terio, Karen A [0000-0003-4924-5503], Millán, Javier [0000-0001-5608-781X], Poulin, Elie [0000-0001-7736-0969], Napolitano, Constanza [0000-0002-7081-6975], Sacristán, Irene, Esperón, Fernando, Pérez, Rubén, Acuña, Francisca, Aguilar, Emilio, García, Sebastián, López, María José, Neves, Elena, Cabello-Stom, Javier, Hidalgo-Hermoso, Ezequiel, Terio, Karen A, Millán, Javier, Poulin, Elie, and Napolitano, Constanza

Abstract

Landscape anthropization has been identified as one of the main drivers of pathogen emergence worldwide, facilitating pathogen spillover between domestic species and wildlife. The present study investigated Carnivore protoparvovirus-1 infection using molecular methods in 98 free-ranging wild guignas (Leopardus guigna) and 262 co-occurring owned, free-roaming rural domestic cats. We also assessed landscape anthropization variables as potential drivers of infection. Protoparvovirus DNA was detected in guignas across their entire distribution range, with observed prevalence of 13.3% (real-time PCR) and 9% (conventional PCR) in guignas, and 6.1% (conventional PCR) in cats. Prevalence in guigna did not vary depending on age, sex, study area or landscape variables. Prevalence was higher in juvenile cats (16.7%) than in adults (4.4%). Molecular characterization of the virus by amplification and sequencing of almost the entire vp2 gene (1,746 bp) from one guigna and five domestic cats was achieved, showing genetic similarities to canine parvovirus 2c (CPV-2c) (one guigna and one cat), feline panleukopenia virus (FPV) (one cat), CPV-2 (no subtype identified) (two cats), CPV-2a (one cat). The CVP-2c-like sequence found in a guigna clustered together with domestic cat and dog CPV-2c sequences from South America, suggesting possible spillover from a domestic to a wild species as the origin of infection in guigna. No clinical signs of disease were found in PCR-positive animals except for a CPV-2c-infected guigna, which had haemorrhagic diarrhoea and died a few days after arrival at a wildlife rescue centre. Our findings reveal widespread presence of Carnivore protoparvovirus-1 across the guigna distribution in Chile and suggest that virus transmission potentially occurs from domestic to wild carnivores, causing severe disease and death in susceptible wild guignas.

Published
2021

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