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3. Mental health and quality of life during weight loss in females with clinically severe obesity: a randomized clinical trial

Author

van den Hoek, Daniel J., Miller, Clint T., Fraser, Steve F., Selig, Steve E., Rice, Toni, Grima, Mariee, and Sari, Carolina Ika

Subjects
Women -- Health aspects, Obesity -- Psychological aspects -- Patient outcomes -- Demographic aspects, Quality of life -- Demographic aspects -- Health aspects, Weight loss -- Demographic aspects -- Psychological aspects, Psychology and mental health
Abstract

The purpose of this investigation was to explore the effects of dietary weight loss intervention, with and without the addition of exercise on health-related quality of life, depressive symptoms, and anxiety. As part of the EMPOWER study for women, sixty premenopausal women (BMI of 40.4 ± 6.7) were randomized to energy restriction only (ER) or to exercise plus energy restriction (EXER) for 12 months. Health-related quality of life was assessed using the SF-36, depressive symptoms were assessed using the Beck Depression Inventory II (BDI), and anxiety symptoms using the Spielberger state and trait anxiety questionnaire. All measures were completed at baseline, 3, 6 and 12 months. At 12 months, there were significant (p < 0.05) group-by-time interactions favouring the EXER group for five of the eight domains and the mental component summary score. At 12 months, a significant group-by-time interaction favouring the EXER group is reported for both state and trait anxiety (p = .005 and p = .001, respectively). At 12 months, there was a significant group-by-time interaction for depressive symptoms favouring EXER (p < 0.05). Within-group changes for BDI scores were improved at all follow-up time points in the EXER group. Exercise training confers an additional benefit to energy restriction in the absence of additional weight loss at 12 months for health-related quality of life, depressive symptoms, and state and trait anxiety scores when compared to energy restriction only. Exercise and an energy-restricted diet improve health-related quality of life and mental health. Exercise may protect mental health without further weight loss for women with severe obesity., Author(s): Daniel J. van den Hoek [sup.1] [sup.2] , Clint T. Miller [sup.1] , Steve F. Fraser [sup.1] , Steve E. Selig [sup.1] , Toni Rice [sup.3] , Mariee Grima [...]

Published
2023
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12. Boosting treatment outcomes via the patient-practitioner relationship, treatment-beliefs or therapeutic setting. A systematic review with meta-analysis of contextual effects in chronic musculoskeletal pain

Author

Saueressig, Tobias, primary, Owen, Patrick J, additional, Pedder, Hugo, additional, Arora, Nitin Kumar, additional, Simons, Marieke, additional, Kaczorowski, Svenja, additional, Miller, Clint T, additional, Donath, Lars, additional, and Belavy, Daniel L, additional

Published
2024
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15. DOSage of Exercise for chronic low back pain disorders (DOSE): protocol for a systematic review with dose-response network meta-analysis.

Author

Arora, Nitin Kumar, Donath, Lars, Owen, Patrick J., Miller, Clint T., Kaczorowski, Svenja, Saueressig, Tobias, Pedder, Hugo, Mundell, Niamh L., Tagliaferri, Scott D., Diwan, Ashish, Xiaolong Chen, Xiaohui Zhao, Huessler, Eva-Maria, Ehrenbrusthoff, Katja, Ford, Jon J., Hahne, Andrew J., Hammel, Ludwig, Norda, Heike, and Belavy, Daniel L.

Published
2024
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21. The importance of context (placebo effects) in conservative interventions for musculoskeletal pain: A systematic review and meta‐analysis of randomized controlled trials.

Author

Saueressig, Tobias, Owen, Patrick J., Pedder, Hugo, Tagliaferri, Scott, Kaczorowski, Svenja, Altrichter, Adina, Richard, Antonia, Miller, Clint T., Donath, Lars, and Belavy, Daniel L.

Abstract

Background and Objective: Contextual effects (e.g. patient expectations) may play a role in treatment effectiveness. This study aimed to estimate the magnitude of contextual effects for conservative, non‐pharmacological interventions for musculoskeletal pain conditions. A systematic review and meta‐analysis of randomized controlled trials (RCTs) that compared placebo conservative non‐pharmacological interventions to no treatment for musculoskeletal pain. The outcomes assessed included pain intensity, physical functioning, health‐related quality of life, global rating of change, depression, anxiety and sleep at immediate, short‐, medium‐ and/or long‐term follow‐up. Databases and Data Treatment: MEDLINE, EMBASE, CINAHL, Web of Science Core Collection, CENTRAL and SPORTDiscus were searched from inception to September 2021. Trial registry searches, backward and forward citation tracking and searches for prior systematic reviews were completed. The Cochrane risk of bias 2 tool was implemented. Results: The study included 64 RCTs (N = 4314) out of 8898 records. For pain intensity, a mean difference of (MD: −5.32, 95% confidence interval (CI): −7.20, −3.44, N = 57 studies with 74 outcomes, GRADE: very low) was estimated for placebo interventions. A small effect in favour of the placebo interventions for physical function was estimated (SMD: −0.22, 95% CI: −0.35, −0.09; N = 37 with 48 outcomes, GRADE: very low). Similar results were found for a broad range of patient‐reported outcomes. Meta‐regression analyses did not explain heterogeneity among analyses. Conclusion: The study found that the contextual effect of non‐pharmacological conservative interventions for musculoskeletal conditions is likely to be small. However, given the known effect sizes of recommended evidence‐based treatments for musculoskeletal conditions, it may still contribute an important component. Significance: Contextual effects of non‐pharmacological conservative interventions for musculoskeletal conditions are likely to be small for a broad range of patient‐reported outcomes (pain intensity, physical function, quality of life, global rating of change and depression). Contextual effects are unlikely, in isolation, to offer much clinical care. But these factors do have relevance in an overall treatment context as they provide almost 30% of the minimally clinically important difference. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Evidence- and data-driven classification of low back pain via artificial intelligence: Protocol of the PREDICT-LBP study

Author

Belavy, Daniel L., primary, Tagliaferri, Scott D., additional, Tegenthoff, Martin, additional, Enax-Krumova, Elena, additional, Schlaffke, Lara, additional, Bühring, Björn, additional, Schulte, Tobias L., additional, Schmidt, Sein, additional, Wilke, Hans-Joachim, additional, Angelova, Maia, additional, Trudel, Guy, additional, Ehrenbrusthoff, Katja, additional, Fitzgibbon, Bernadette, additional, Van Oosterwijck, Jessica, additional, Miller, Clint T., additional, Owen, Patrick J., additional, Bowe, Steven, additional, Döding, Rebekka, additional, and Kaczorowski, Svenja, additional

Published
2023
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28. The Interaction Between Psychosocial Factors and Exercise-Induced Hypoalgesia in Pain-Free Nurses

Author

Johnsen,Kristian, Owen,Patrick J, Tagliaferri,Scott D, Van Oosterwijck,Jessica, Fitzgibbon,Bernadette M, Ford,Jon J, Belavy,Daniel L, Miller,Clint T, Johnsen,Kristian, Owen,Patrick J, Tagliaferri,Scott D, Van Oosterwijck,Jessica, Fitzgibbon,Bernadette M, Ford,Jon J, Belavy,Daniel L, and Miller,Clint T

Abstract

Kristian Johnsen,1 Patrick J Owen,1 Scott D Tagliaferri,1 Jessica Van Oosterwijck,2– 4 Bernadette M Fitzgibbon,5 Jon J Ford,6,7 Daniel L Belavy,1,8 Clint T Miller1 1Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia; 2Spine, Head and Pain Research Unit Ghent, Department of Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium; 3Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium; 4Research Foundation – Flanders (FWO), Brussels, Belgium; 5School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia; 6Advance HealthCare, Boronia, VIC, Australia; 7Low Back Research Team, College of Science, Health and Engineering, La Trobe University, Bundoora, VIC, Australia; 8Department of Applied Health Sciences, Division of Physiotherapy, Hochschule für Gesundheit, Bochum, GermanyCorrespondence: Clint T Miller, Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Highway, Burwood, VIC, 3125, Australia, Tel +61 3 9244 6605, Email c.miller@deakin.edu.auPurpose: This cross-sectional study aimed to investigate whether psychosocial factors were predictive for exercise-induced hypoalgesia (EIH) in pain-free adults.Methods: A sample of 38 pain-free nurses with a mean (SD) age of 26 (6) years were included in this study. Participants completed psychosocial questionnaires prior to physical tests. Pressure pain threshold (PPT) was assessed bilaterally at the calves (local), lower back (semi-local) and forearm (remote) before and immediately after a maximal graded cycling exercise test. Separate linear mixed effects models were used to determine change in PPT before and after cycling exercise (EIH). Multiple linear r

Published
2023

30. Assessing safety and treatment efficacy of running on intervertebral discs (ASTEROID) in adults with chronic low back pain: protocol for a randomised controlled trial

Author

Tagliaferri, Scott D, primary, Belavy, Daniel L, additional, Bowe, Steven J, additional, Clarkson, Matthew J, additional, Connell, David, additional, Craige, Emma A, additional, Gollan, Romina, additional, Main, Luana C, additional, Miller, Clint T, additional, Mitchell, Ulrike H, additional, Mundell, Niamh L, additional, Neason, Christopher, additional, Samanna, Claire L, additional, Scott, David, additional, Tait, Jamie L, additional, Vincent, Grace E, additional, and Owen, Patrick J, additional

Published
2023
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32. Classifying Nonspecific Low Back Pain for Better Clinical Outcomes: Current Challenges and Paths Forward.

Author

TAGLIAFERRI, SCOTT D., OWEN, PATRICK J., MILLER, CLINT T., MITCHELL, ULRIKE H., EHRENBRUSTHOFF, KATJA, and BELAVY, DANIEL L.

Abstract

SYNOPSIS: Low back pain classification systems are structured assessments used to guide choices of more specific treatments. Classification systems examined in randomized controlled trials have limited effects on pain intensity and disability compared to nonclassified interventions. Potential reasons for the lack of efficacy include (1) failing to assess multidimensional factors that contribute to pain, (2) relying on clinician judgement, (3) low accessibility, and (4) poor classification reliability. Overcoming these limitations is critical to deciding whether classification systems can improve clinical practice. Only once these limitations are addressed, can we feel certain about the efficacy, or lack thereof, of classification systems. This Viewpoint guides the reader through some limitations of common classification approaches and presents a path forward to open-access, reliable, and multidimensional precision medicine for managing low back pain. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Network meta-analysis for comparative effectiveness of treatments for chronic low back pain disorders: systematic review protocol

Author

Belavy, Daniel L, primary, Diwan, Ashish D, additional, Ford, Jon, additional, Miller, Clint T, additional, Hahne, Andrew J, additional, Mundell, Niamh, additional, Tagliaferri, Scott, additional, Bowe, Steven, additional, Pedder, Hugo, additional, Saueressig, Tobias, additional, Zhao, Xiaohui, additional, Chen, Xiaolong, additional, Balasundaram, Arun Prasad, additional, Arora, Nitin Kumar, additional, and Owen, Patrick J, additional

Published
2021
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45. Randomised trial of general strength and conditioning versus motor control and manual therapy for chronic low back pain on physical and self-report outcomes

Author

Tagliaferri, Scott D., Miller, Clint T., Ford, Jon J., Hanhe, Andrew J., Main, Luana C., Rantalainen, Timo, Connell, David A., Simson, Katherine J., Owen, Patrick J., Belavy, Daniel L., Tagliaferri, Scott D., Miller, Clint T., Ford, Jon J., Hanhe, Andrew J., Main, Luana C., Rantalainen, Timo, Connell, David A., Simson, Katherine J., Owen, Patrick J., and Belavy, Daniel L.

Published
2020

46. Fitness, strength and body composition during weight loss in women with clinically severe obesity: a randomised clinical trial

Author

Miller, Clint T, Fraser, Steve F, Selig, Steven, Rice, Toni, Grima, Mariee, van den Hoek, Daniel J, Ika Sari, Carolina, Lambert, Gavin W, Dixon, John B, Miller, Clint T, Fraser, Steve F, Selig, Steven, Rice, Toni, Grima, Mariee, van den Hoek, Daniel J, Ika Sari, Carolina, Lambert, Gavin W, and Dixon, John B

Abstract

Introduction: To determine whether combined exercise training with an energy-restricted diet leads to improved physical fitness and body composition when compared to energy restriction alone in free-living premenopausal women with clinically severe obesity. Methods: Sixty premenopausal women (BMI of 40.4 ± 6.7) were randomised to energy restriction only (ER) or to exercise plus energy restriction (EXER) for 12 months. Body composition and fitness were measured at baseline, 3, 6 and 12 months. VO2 peak improved more for EXER compared to ER at 3 (mean difference ± SEM 2.5 ± 0.9 mL ∙ kg–1 ∙ min–1, p = 0.006) and 6 (3.1 ± 1.2 mL ∙ kg–1 ∙ min–1, p = 0.007) but not 12 months (2.3 ± 1.6 mL ∙ kg–1 ∙ min–1, p = 0.15). Muscle strength improved more for EXER compared to ER at all time points. No differences between groups for lean mass were observed at 12 months. Conclusion: Combining exercise training with an energy-restricted diet did not lead to greater aerobic power, total body mass, fat mass or limit lean body mass loss at 12 months when compared to energy restriction alone for premenopausal women with clinically severe obesity in free-living situations. Future research should aim to determine an effective lifestyle approach which can be applied in the community setting for this high-risk group.

Published
2020

49. Randomized Trial of General Strength and Conditioning versus Motor Control and Manual Therapy for Chronic Low Back Pain on Physical and Self-Report Outcomes

Author

Tagliaferri, Scott D., primary, Miller, Clint T., additional, Ford, Jon J., additional, Hahne, Andrew J., additional, Main, Luana C., additional, Rantalainen, Timo, additional, Connell, David A., additional, Simson, Katherine J., additional, Owen, Patrick J., additional, and Belavy, Daniel L., additional

Published
2020
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