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Objective: Recent evidence reported that some dietary compounds like quercetin and apigenin as the most well-known flavonoids with anti-inflammatory effects may inhibit SARS-CoV-2 main protease. The hypothesis of the promising effects and possible mechanisms of action of quercetin against COVID-19 were assessed in this article.Materials and Methods: Related papers on the inhibitory effects of quercetin against COVID-19 were collected using the following search strategy: “corona or coronavirus or COVID or COVID-19 or viral or virus” AND “nutrient or flavonoid or Quercetin”.Results: The findings indicated that quercetin can be considered an effective agent against COVID-19 because of its SARS-CoV-2 main protease and RNA-dependent RNA polymerase inhibitory effects. In addition, quercetin may attenuate angiotensin-converting enzyme-2 (ACE-2) receptors leading to a reduction of SARS-CoV-2 ability to enter host cells. Moreover, the antiviral, anti-inflammatory, and immunomodulatory activities of quercetin have been frequently reported.Conclusion: Quercetin may be an effective agent for managing the complications of COVID-19. Further longitudinal human studies are warranted.

The aim of this study was to investigate the effect of three components of transaction costs including uncertainty, specific assets and frequency on outsourcing and also to investigate the specific assets and uncertainty on open innovation abroad among banking financial technology companies based in Tehran. The research method was descriptive-correlational, based on which the required information was collected randomly among 123 managers of technology companies by compiling and distributing a researcher-made questionnaire. The results of the analysis of research data with the help of structural equation modeling technique and partial least squares approach show that the increase of specific assets reduces outsourcing and increases the export of open innovation. Rising uncertainty reduces outsourcing and increases open export exports. Increasing the frequency of exchanges also reduces outsourcing.