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23 results on '"Minor, Jacob"'

3. Prevalence and Spatial Distribution of Gastroschisis in an Industrial Watershed.

Author

Minor, Jacob, Wells, Amy, Orminski, Krysta, Thompson, Stephanie N., Annie, Frank, Robinson, Lindsey, Calhoun, Byron C., and Haricharan, Ramanathapura N.

Subjects
*GASTROSCHISIS, *HAZARDOUS waste sites, *POLLUTION, *WATERSHEDS, *MATERNAL age, *TOBACCO use
Abstract

The relationship between the congenital defect of gastroschisis and environmental toxins is poorly understood. We examined gastroschisis incidence, risk factors, and spatial association in a geographic region with known environmental pollution and hazardous waste sites. An observational study of fetal and neonatal gastroschisis diagnosed from 1/1/2006 to 12/31/2020 was conducted in a southern West Virginia (WV) tertiary care hospital. Emerging hot spot analysis and Ripley's K-Function examined the spatial relationship between gastroschisis cases and Environmental Protection Agency (EPA) Federal Registry Sites (FRS). A total of 63 gastroschisis cases provided a prevalence rate of 14.6 per 10000 live births. Gastroschisis was associated with younger maternal age, decreased pre-pregnancy BMI, and increased maternal tobacco use. Relative to FRS sites, spatial clusters were identified with emerging hot spot analysis. Observed Ripley K was higher at all measured bands. Results suggest a potential geographic association between gastroschisis cases and EPA-designated hazardous waste sites. [ABSTRACT FROM AUTHOR]

Published
2023
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4. Recurrent Volvulus After Ladd Procedure

Author

Momoh, Salamatu, primary, Okakpu, Uchenna, additional, Minor, Jacob, additional, Walker, Andrew P., additional, Richmond, Bryan K., additional, and Haricharan, Ramanathapura N., additional

Published
2022
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9. Clinical and Socioeconomic Factors that Predict Non-completion of Adjuvant Chemotherapy for Colorectal Cancer in a Rural Cancer Center

Author

Knotts, Chelsea, Van Horn, Alexandra, Orminski, Krysta, Thompson, Stephanie, Minor, Jacob, Elmore, Michael, and Richmond, Bryan K.

Abstract

Background Previous literature demonstrates correlations between comorbidities and failure to complete adjuvant chemotherapy. Frailty and socioeconomic disparities have also been implicated in affecting cancer treatment outcomes. This study examines the effect of demographics, comorbidities, frailty, and socioeconomic status on chemotherapy completion rates in colorectal cancer patients.Methods This was an observational case-control study using retrospective data from Stage II and III colorectal cancer patients offered chemotherapy between January 01, 2013 and January 01, 2018. Data was obtained using the cancer registry, supplemented with chart review. Patients were divided based on treatment completion and compared with respect to comorbidities, age, Eastern Cooperative Oncology Group (ECOG) score, and insurance status using univariate and multivariate analyses.Results 228 patients were identified: 53 Stage II and 175 Stage III. Of these, 24.5% of Stage II and 30.3% of Stage III patients did not complete chemotherapy. Neither ECOG status nor any comorbidity predicted failure to complete treatment. Those failing to complete chemotherapy were older (64.4 vs 60.8 years, P= .043). Additionally, those with public assistance or self-pay were less likely to complete chemotherapy than those with private insurance (P= .049). Both factors (older age/insurance status) remained significant on multivariate analysis (increasing age at diagnosis: OR 1.03, P=.034; public insurance: OR 1.84, P= .07; and self-pay status: OR 4.49, P= .03).Conclusions No comorbidity was associated with failure to complete therapy, nor was frailty, as assessed by ECOG score. Though frailty was not significant, increasing age was, possibly reflecting negative attitudes toward chemotherapy in older populations. Insurance status also predicted failure to complete treatment, suggesting disparities in access to treatment, affected by socioeconomic factors.

Published
2023
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22. Esterification of Methylolated Rosin

Author

Minor Jacob C and Ray V. Lawrence

Subjects
Materials science, General Engineering, Rosin, medicine, Organic chemistry, medicine.drug
Published
1958

23. LETTERS.

Author

Alford, Mac H., Johnson, Phillip E., Minor, Jacob S., Schansberg, Eric, Mills, David, Kelley, Steven, Meldrim, James, Marshall, Ronald F., and Sherwood, John

Subjects
*LETTERS to the editor, *CONSENSUS (Social sciences), *SOCIAL reality, *CONDUCT of life, *SALVATION
Abstract

Several letters to the editor are presented in response to articles in previous issues including "Science by Consensus," by Phillip Johnson in the March 2008 issue, "That All May Be Saved," by David Mills in the April 2008 issue, and "Eaten Alive," by Ronald F. Marshall in the April 2008 issue.

Published
2008

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