215 results on '"Minton S"'
Search Results
2. Retraction Note: Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer
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Zheng, X. Q., Guo, J. P., Yang, H., Kanai, M., He, L. L., Li, Y. Y., Koomen, J. M., Minton, S., Gao, M., Ren, X. B., Coppola, D., and Cheng, J. Q.
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- 2024
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3. High vs low CPAP strategy with aerosolized calfactant in preterm infants with respiratory distress syndrome
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Kaluarachchi, D. C., primary, Gerday, E., additional, Bahr, T., additional, Zapata, H. A., additional, Lasarev, M. R., additional, Guthrie, S. O., additional, and Minton, S., additional
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- 2024
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4. Active Learning with Multiple Views
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Knoblock, C. A., Minton, S., and Muslea, I.
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Computer Science - Learning - Abstract
Active learners alleviate the burden of labeling large amounts of data by detecting and asking the user to label only the most informative examples in the domain. We focus here on active learning for multi-view domains, in which there are several disjoint subsets of features (views), each of which is sufficient to learn the target concept. In this paper we make several contributions. First, we introduce Co-Testing, which is the first approach to multi-view active learning. Second, we extend the multi-view learning framework by also exploiting weak views, which are adequate only for learning a concept that is more general/specific than the target concept. Finally, we empirically show that Co-Testing outperforms existing active learners on a variety of real world domains such as wrapper induction, Web page classification, advertisement removal, and discourse tree parsing.
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- 2011
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5. Wrapper Maintenance: A Machine Learning Approach
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Knoblock, C. A., Lerman, K., and Minton, S. N.
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Computer Science - Artificial Intelligence - Abstract
The proliferation of online information sources has led to an increased use of wrappers for extracting data from Web sources. While most of the previous research has focused on quick and efficient generation of wrappers, the development of tools for wrapper maintenance has received less attention. This is an important research problem because Web sources often change in ways that prevent the wrappers from extracting data correctly. We present an efficient algorithm that learns structural information about data from positive examples alone. We describe how this information can be used for two wrapper maintenance applications: wrapper verification and reinduction. The wrapper verification system detects when a wrapper is not extracting correct data, usually because the Web source has changed its format. The reinduction algorithm automatically recovers from changes in the Web source by identifying data on Web pages so that a new wrapper may be generated for this source. To validate our approach, we monitored 27 wrappers over a period of a year. The verification algorithm correctly discovered 35 of the 37 wrapper changes, and made 16 mistakes, resulting in precision of 0.73 and recall of 0.95. We validated the reinduction algorithm on ten Web sources. We were able to successfully reinduce the wrappers, obtaining precision and recall values of 0.90 and 0.80 on the data extraction task.
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- 2011
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6. Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial
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Sabatine, Marc S, Wiviott, Stephen D, Scirica, Benjamin M, Inzucchi, Silvio, Keech, Anthony, McGuire, Darren K, Smith, Steven R, Satlin, Andrew, Brown, Conville, Budaj, Andrzej, Corbalan, Ramon, Dwyer, Jamie, Garcia-Castillo, Armando, Gupta, Milan, Hamm, Christian, Kaplan, Lee, Leiter, Lawrence A, Nicolau, Jose Carlos, Oude Ophuis, Ton, Ray, Kauski, Ruda, Mikhail, Spinar, Jindrich, Weissman, Neil, White, Harvey D, Amerena, J, Arstall, M, Colquhoun, D, Jayasinghe, R, Lee, A, Lehman, R, Moses, R, Proietto, J, Purnell, P, Waites, J, Blombery, P, Cross, D, Worthley, M, d'Emden, M, Selvanayagam, J, Oqueli, RE, Whelan, A, Garrahy, P, de Looze, F, Ninio, D, Horowitz, J, William, M, Suranyi, M, Wittert, G, Le May, M, Pandey, AS, Vizel, S, Labonte, R, Beaudry, Y, Fortin, C, Bell, A, Kouz, S, St-Amour, É, Bata, I, St Maurice, F, Chehayeb, R, Constance, C, Wong, G, Hess, A, Liutkus, J, Poirier, P, Teitelbaum, I, Berlingieri, J, Cha, J, Hartleib, M, Heffernan, M, Twum-Barima, D, Pandith, V, Aronson, R, Goldenberg, R, Ajala, B, Jain, A, Ross, S, Bajaj, H, Khandwala, H, Yared, Z, Gupta, N, Bédard, J, Wharton, S, Blouin, F, Savard, D, Shukla, D, Cobos, J, Godoy, G, Perez, L, Pincetti, C, Saavedra Guajardo, V, Varleta, P, Conejeros, C, Lanas, F, Bayram Llamas, E, Cardona Muñoz, E, Garcia, R, Garza Ruiz, J, Llamas Esperon, G, Lopez Rosas, E, Melendez Mier, G, Ramos, G, Hart, H, Scott, D, Ternouth, I, Benatar, J, Elliott, J, Cutfield, R, Manning, P, Williams, M, Ferrier, K, Scott, R, Wilson, S, Leikis, R, Nirmalaraj, BK, Krzyżagórska, E, Miękus, P, Bronisz, M, Mirek-Bryniarska, E, Łanda, K, Stasiewski, A, Żechowicz, T, Zytkiewicz-Jaruga, D, Korecki, J, Ogórek, M, Pawłowicz, L, Piepiorka, M, Skierkowska, J, Stankiewicz, A, Szyprowska, E, Witek, R, Bochenek, A, Kończakowski, P, Wojnowski, Ł, Wujkowski, M, Cymerman, K, Korzeniak, R, Mąder, P, Mikłaszewicz, B, Stachlewski, P, Goch, A, Pomiećko, W, Skórski, M, Romanowski, L, Jusiak, K, Laskowska-Derlaga, E, Bijata-Bronisz, R, Kaźmierczak, J, Goldberg, R, Henderson, D, Korban, E, Rohr, K, Claxton, E, Weiss, R, Angiolillo, D, Boccalandro, F, Chu, K, Thorn, E, Randhawa, P, Singh, N, Bittar, G, Guarnieri, T, Saeed, S, Sharma, S, Shepard, M, French, W, Desai, P, Bernstein, R, Rogers, W, Singal, R, Schneider, R, Shanes, J, Ong, S, Condit, J, Donahoe, S, Brill, D, Einhorn, D, Ebrahimi, R, Labroo, A, Graf, R, Scott, J, Hoekstra, J, Jetty, P, Luckasen, G, O'Donnell, P, Gonte, W, Pomposini, D, Quadrel, M, Koren, M, Schlager, D, Schramm, E, Singal, D, Lupovitch, S, Soni, A, Seigel, P, Roberts, J, Soufer, J, Reza, S, Quinlan, E, Moretto, T, First, B, Khan, M, Chilka, S, Colfer, H, Teklinski, A, Wallace-Wilding, K, Ellison, H, Muse, D, Aronoff, S, Higgins, A, Patel, S, Elinoff, V, Karim, A, Awasty, V, Chuang, R, Roseman, H, Dugano-Daphnis, P, Albert, M, Sheikh, K, Bays, H, Kaster, S, Goldstein, M, Rubino, D, Calatayud, G, Snyder, H, Williams, T, Hershon, K, Hagan, M, Isserman, S, Kahn, B, Anderson, J, Gimness, MP, Raisinghani, A, Christina, M, Raikhel, M, Gillespie, E, Portnay, E, Heiman, M, Qureshi, M, Lee, J, Blonder, R, Cucher, F, Miller, G, Kotlaba, D, Cornett, G, Beavins, J, Augenbraun, C, Reinhardt, S, Bartkowiak, A, Jr, Salacata, A, Blevins, T, Benjamin, S, Diener, J, George, W, Barker, B, Richwine, R, Baldari, D, Alfieri, A, Barreto, A, Zhang, L, Shah, R, Hendrix, E, Subramaniyam, V, Hurley, S, Lillestol, M, O'Donoghue, M, Shayani, S, Ryan, E, Call, R, Zemel, L, Chang, A, Kivitz, A, Freyne, B, Bland, V, Shore, K, Mostel, E, Uzoaga, E, Andrawis, N, Gabra, N, Ghitis, A, Sabatino, K, Browder, D, Varma, S, Smith, S, Fink, R, Aycock, GR, Jr, Doty, WD, Alfonso, T, Eshaghian, S, Karlsberg, R, Zarich, S, Landau, C, McKenzie, M, Krause, R, Davis, W, Haddad, T, Voyce, S, Alford, C, LeDoux, J, O'Dea, D, Park, J, Aroda, V, Getaneh, A, Graham, B, Bhagwat, R, Korn, D, Ruoff, G, Wiseman, A, Lieber, I, Fialkow, J, Gonzalez-Campoy, JM, Bayron, C, Bertolet, B, Lash, J, Gerrish, C, Robertson, D, Rosenfeld, J, Seidner, M, Agaiby, J, Silverfield, J, Sugimoto, D, Lubin, B, Alhaddad, M, Lui, H, Lakin, G, Chokshi, S, Donovan, D, Felten, W, Minton, S, Kimmelstiel, C, Kuvin, J, Still, C, Byars, W, Talano, J, Desai, V, Bradley, AJ, III, Baker, S, Chane, M, Mercado, A, Baron, S, Harris, B, Mayer, N, Concha, M, Carr, K, Chaykin, L, Willis, J, Clay, A, Fenstad, E, Furda, J, Peterson, P, Chang, M, Aronne, L, Jones, D, Prashad, R, Benson, M, Stegemoller, R, Longshaw, K, Saleh, J, Jennings, W, Detweiler, R, Viswanath, D, Patel, R, Lederman, S, Weinstein, D, Korabathina, R, Singh, V, Rosen, J, Estevez, R, Levin, P, McNeill, R, Kalen, V, Reed, J, Ashley, R, Herman, L, Tsai, Y, Kayne, D, White, A, Hussain, I, Tami, L, Cohen, K, Robinson, J, Fuchs-Ertman, D, Platt, G, Belardo, L, Reddy, R, Rosendorff, C, Saba, F, Powell, S, Anderson, K, Abidi, M, Rezkalla, S, Paraschos, A, Wilson, J, Moursi, M, Shah, A, Nadar, V, Stonesifer, L, Bialow, M, Cannon, K, Ellison, W, Stedman, M, Brown, J, Harper, W, Lucas, KJ, DiGiovanna, M, Rodbard, H, Biscoveanu, M, Davis, C, Hall, J, Littlefield, R, Gorman, T, Kereiakes, D, Chang, FM, Tatu, H, Cheung, D, Kaine, J, Knutson, T, Logemann, T, Pueblitz, G, Bianco, J, Henson, B, Neustel, M, Gelernt, M, Nelson, W, Moriarty, K, Lefebvre, G, Maw, K, Rink, L, Behn, P, Studdard, H, Argoud, G, O'Connor, T, Krichmar, P, Raad, G, Pereles-Ortiz, J, Sorli, C, Cohen, A, Pettis, K, Cavanaugh, B, Phillips, C, Wahlen, J, Radin, D, Rider, J, Kosinski, E, Leimbach, W, Odhav, A, Hakas, J, Tan, A, Howell, M, Wombolt, D, Fishman, N, Shah, P, Wylie, P, Arauz-Pacheco, C, Cavale, A, George, A, Kroll, R, Krantzler, J, Tahirkheli, N, Jabro, M, Newell, M, Mullen, P, Gencheff, N, Meli, J, Vora, K, Kotek, L, Pyzdrowski, K, Paez, H, Moran, J, Tannenbaum, A, Deck, K, Busch, R, Levinson, L, Azizad, M, Whitaker, J, Fox, B, Huffman, C, Ashraf, M, Diogo, J, Kushner, R, Tallet, J, Channamsetty, V, Suh, D, Atieh, M, Navas, J, Young, V, Shaw, S, Dor, I, Duffy, B, Rubin, P, Lewis, D, Kaye, W, Benton, R, Burbano, J, Hotchkiss, D, Magno, A, Alberton, A, Collins, J, Alvarado, O, Stich, M, Mahal, S, Liu, J, Hong, M, Dy, J, Block, B, Lamantia, J, Pritchard, J, Davis, M, Srivastava, S, Bilazarian, S, Rosario, R, McCartney, M, Blumberg, V, Rajan, R, Martin, E, Wright, S, Brinson, C, Johnston, J, Graves, M, Dominguez, M, McKenzie, W, Abadier, R, Tran, C, Castello, R, Morawski, E, White, J, Morris, F, Perez, A, Trueba, P, Sanchez, M, Andersen, J, Kastelic, R, Khan, J, Rodriguez, H, Izquierdo, W, Matias, A, Essandoh, L, Ince, C, Bohula, Erin A, Inzucchi, Silvio E, Keech, Anthony C, Kanevsky, Estella, Murphy, Sabina A, Dwyer, Jamie P, Ophuis, Ton Oude, Ray, Kausik K, Patel, Tushar, Miao, Wenfeng, Perdomo, Carlos, Francis, Bruce, Dhadda, Shobha, Bonaca, Marc P, and Ruff, Christian T
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- 2018
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7. Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker
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Munster, PN, Marchion, D, Thomas, S, Egorin, M, Minton, S, Springett, G, Lee, J-H, Simon, G, Chiappori, A, Sullivan, D, and Daud, A
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Biomedical and Clinical Sciences ,Clinical Sciences ,Oncology and Carcinogenesis ,Immunology ,Breast Cancer ,Cancer ,Clinical Trials and Supportive Activities ,Prostate Cancer ,Clinical Research ,Evaluation of treatments and therapeutic interventions ,6.1 Pharmaceuticals ,Acetylation ,Adult ,Aged ,Aged ,80 and over ,Antineoplastic Combined Chemotherapy Protocols ,Doxorubicin ,Female ,Heart ,Histone Deacetylase Inhibitors ,Histone Deacetylases ,Histones ,Humans ,Hydroxamic Acids ,Male ,Middle Aged ,Neoplasms ,Vorinostat ,DNA topoisomerases ,type II ,histone deacetylases ,doxorubicin ,clinical trials ,phase I ,chromatin decondensation ,Public Health and Health Services ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
BackgroundHistone deacetylase inhibitors (HDACi) can sensitise cancer cells to topoisomerase inhibitors by increasing their access and binding to DNA.MethodsThis phase I trial was designed to determine the toxicity profile, tolerability, and recommended phase II dose of escalating doses of the HDACi vorinostat, with weekly doxorubicin.ResultsIn total, 32 patients were treated; vorinostat was dosed at 400, 600, 800, or 1000 mg day(-1) on days 1-3, followed by doxorubicin (20 mg m(-2)) on day 3 for 3 of 4 weeks. Maximal tolerated dose was determined to be 800 mg day(-1) of vorinostat. Dose-limiting toxicities were grade 3 nausea/vomiting (two out of six) and fatigue (one out of six) at 1000 mg day(-1). Non-dose-limiting grade 3/4 toxicities included haematological toxicity and venous thromboembolism. Antitumor activity in 24 evaluable patients included two partial responses (breast and prostate cancer). Two patients with melanoma had stable disease for > or =8 months. Histone hyperacetylation changes in peripheral blood mononuclear and tumour cells were comparable. Histone hyperacetylation seemed to correlate with pre-treatment HDAC2 expression.ConclusionThese findings suggest that vorinostat can be combined with weekly doxorubicin in this schedule at a dose of 800 mg day(-1). The HDAC2 expression may be a marker predictive of HDAC inhibition. Antitumor activity of this regimen in breast cancer, prostate cancer, and melanoma seems interesting.
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- 2009
8. No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease
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Ansari, S., Ayub, K., Basile, A., Behrend, C., Bercik, P., Bressler, B., Byrnes, V., Chandan, V.S., Cheekati, V., Chipps, B., Coates, A., Collatrella, A., Condemi, J., Corder, C., Corren, J., Curtis, C., DeMeo, M., Desta, T., Devereaux, C., DiMarino, A., DuPree, M., Ennis, C., Fedorak, R., Fogel, R., Freeman, S., Freilich, B., Friedenberg, K., Geenen, D., Gill, K., Goldsobel, A., Goldstein, J., Goldstein, M., Gordon, G., Hardi, R., Harris, L., Holmes, R., Jagarlamundi, K., James, G., Kaplan, M., Kirstein, J., Knoll, A., Kotfila, R., Krause, R., Kravitz, A., Kreines, M., Lähdeaho, M.L., Lamet, M., Laskin, K., Lebwohl, B., Leffler, D., Lewis, S., Liakos, S., Lundin, K., Marks, K., Merkes, K., Minton, S., Moussa, S., Narayen, V., Nehra, V., Newton, E., Nyberg, A., Oosthuizen, J., Otrok, T., Patel, D., Pepin, C., Phillips, R., Pyle, G., Reichelderfer, M., Reid, B., Ritter, T., Saini, S., Sanders, D., Schulman, M., Semrad, C., Shah, S., Stockwell, D., Strout, C., Suez, D., Tatum, H., Torbenson, M.S., Turner, M., Varunok, P., Vazquez-Roque, M., Vento, A., Welton, T., Wohlman, R., Wood, M., Woods, S., Yousef, K., Murray, Joseph A., Kelly, Ciarán P., Green, Peter H.R., Marcantonio, Annette, Wu, Tsung-Teh, Mäki, Markku, and Adelman, Daniel C.
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- 2017
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9. Total-Order and Partial-Order Planning: A Comparative Analysis
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Minton, S., Bresina, J., and Drummond, M.
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Computer Science - Artificial Intelligence - Abstract
For many years, the intuitions underlying partial-order planning were largely taken for granted. Only in the past few years has there been renewed interest in the fundamental principles underlying this paradigm. In this paper, we present a rigorous comparative analysis of partial-order and total-order planning by focusing on two specific planners that can be directly compared. We show that there are some subtle assumptions that underly the wide-spread intuitions regarding the supposed efficiency of partial-order planning. For instance, the superiority of partial-order planning can depend critically upon the search strategy and the structure of the search space. Understanding the underlying assumptions is crucial for constructing efficient planners., Comment: See http://www.jair.org/ for an online appendix and other files accompanying this article
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- 1994
10. Conditions for the Implementation of Anti-Bullying Programmes in Norway and Ireland: A Comparison of Contexts and Strategies
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Midthassel, U. V., Minton, S. J., and O'Moore, A. M.
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Drawing on experiences from anti-bullying programmes in Norway and Ireland, our primary objective in this paper is to present and discuss similarities and differences in national contexts, delivery strategies and strategies at school level for implementation of the ABC (Ireland) and Zero (Norway) anti-bullying programmes. Both programmes are whole-school anti-bullying programmes that share a common structure and marked similarities in methodology, emanating from a Norwegian nationwide anti-bullying programme developed at the Centre for Behavioural Research. Comparisons show considerable differences in the national contexts, with the Norwegian authorities taking more initiative towards anti-bullying work. There were both similarities and differences concerning delivery strategies. A conclusion to be drawn is that in order to stimulate implementation of anti-bullying programmes in schools, the national authorities can have a promoting role through their focus, legislation and resource allocation. However, conditions for implementation also include the delivery process and strategies for implementation at the school level.
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- 2009
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11. On the proposed precedence of the specific name of Crotalus ruber Cope, 1892 over that of Crotalus exsul Garman, 1884 (Reptilia, Serpentes)
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Minton, S A, Olson, R E, Tanner, W W, Murphy, R W, Brattstrom, B H, Ramirez-Bautista, A, Espinal, J L, and BioStor
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- 1999
12. Why do four NICUs using identical RBC transfusion guidelines have different gestational age-adjusted RBC transfusion rates?
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Henry, E, Christensen, R D, Sheffield, M J, Eggert, L D, Carroll, P D, Minton, S D, Lambert, D K, and Ilstrup, S J
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- 2015
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13. RETRACTED ARTICLE: Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer
- Author
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Zheng, X Q, Guo, J P, Yang, H, Kanai, M, He, L L, Li, Y Y, Koomen, J M, Minton, S, Gao, M, Ren, X B, Coppola, D, and Cheng, J Q
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- 2014
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14. Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer
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Zheng, X Q, Guo, J P, Yang, H, Kanai, M, He, L L, Li, Y Y, Koomen, J M, Minton, S, Gao, M, Ren, X B, Coppola, D, and Cheng, J Q
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- 2014
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15. Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial
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Bhatt, D, Steg, P, Mehta, S, Leiter, L, Simon, T, Fox, K, Held, C, Andersson, M, Himmelmann, A, Ridderstrale, W, Chen, J, Song, Y, Diaz, R, Goto, S, James, S, Ray, K, Parkhomenko, A, Kosiborod, M, Mcguire, D, Harrington, R, Santos, V, Jain, A, Lendel, I, Russo, M, Haught, W, Bouza, M, Gogia, H, Banerjee, S, Kichura, G, Kantaros, L, Padron, F, Passi, R, Stone, J, Pursley, M, D'Urso, M, Gardner, T, Bennett, J, Nour, K, Saini, S, Zhang, W, Kumbhani, D, Thomas, D, Angiolillo, D, Bertolet, B, Roman-Miranda, A, Black, R, Manshadi, R, Vaca, C, Blanco, A, Napoli, M, Brabham, D, Akyea-Djamson, A, Desai, P, Prasada, S, Khaira, A, Forgosh, L, Lieber, I, Umpierrez, G, Singal, D, Londono, J, Fraser, N, Ruiz, J, Vega, D, Rodriguez, L, Brown, C, Syed, F, Aggarwala, G, Eaves, W, Foster, M, Gupta, D, Avino, D, Asfour, W, Tonnessen, G, Zhao, X, Singh, N, Brockmyre, A, Lepor, N, Shammas, N, Blick, D, Hearne, S, Prodafikas, J, Carell, E, Izzo, M, Karim, A, Zakhary, B, Atieh, M, Leichter, S, Meadows, C, Hotchkiss, D, Abu-Fadel, M, Wiseman, A, Bander, J, Shah, M, Ganim, R, Sopko, K, Khan, M, Lloret, R, Weirick, T, Mehta, R, Thadani, U, Bhargava, A, Moya, J, Staniloae, C, Guerra, Y, Chhabra, A, Kosmicki, D, Shaheen, W, Mohammed, A, Bitters, J, Pattanayak, J, Javier, J, Srivastava, S, Phillips, R, Al-Amin, J, Lillestol, M, Simpson, P, Hazan, L, Amin, A, Shah, G, Korpas, D, Platt, B, Dickert, J, Puente, O, Hiotis, L, Doyle, T, Rajan, R, Meholick, A, Gring, C, Hage-Korban, E, Feldman, R, Colfer, H, Butman, S, Hart, T, Huling, R, Eshaghian, S, Quintana, O, Cheung, D, Handel, F, Rodriguez, M, Suh, D, Gordon, P, Pressman, G, Bauer, M, French, W, Barettella, M, Chatrathi, S, Suresh, D, Goldberg, R, Huth, M, Younis, L, Rahman, A, Mascolo, R, Welch, M, Suneja, R, Smith, S, Shurmur, S, Agaiby, J, Jingo, A, Johnston, J, Beth, M, Vlastaris, A, Kemp, S, Taheri, H, Pereira, E, Deyoung, M, Hawa, Z, Smith, R, Galski, T, Garas, S, Reddy, M, Sharma, S, Hargrove, J, Treasure, C, Emerson, R, Haddad, T, Rohr, K, Levinson, L, Gaona, R, Uretsky, B, Maheshwari, H, Lee, D, Kinnaman, S, Singal, R, Geohas, J, Gigliotti, O, Raisinghani, A, Khurana, C, Hella, B, Kelberman, M, Voyce, S, Singh, S, Lo, E, Singh, P, Goodfellow, R, Fischer, S, Lorraine, R, Turner, T, Shanes, J, Busch, R, Broker, R, Zaniewski, M, Pounds, K, Debs-Perez, G, Ong, S, Frandsen, B, Fullington, D, Jaffrani, N, Khan, A, Lee, M, Pouzar, J, Revtyak, G, Gonzalez, J, Nakhle, S, Murillo, A, Young, D, Makam, S, Syed, M, Woolf, K, Grena, P, Alfata, S, Mahal, S, Hoffman, D, Kizhakekuttu, T, Deering, J, Bhavsar, J, Mikesell, S, Wilson, W, Wilson, V, El, S, Spinale, F, Kannarkat, V, Rao, S, Hanson, L, Bertsch, J, Gonzalez-Ortiz, E, Severino, N, Willis, J, Schock, J, Bakhtari, L, Gazmuri, R, Ansari, S, Hall, J, Mehta, A, Shealy, N, Zarich, S, Singh, D, Vora, K, Andrawis, N, Molter, D, Maron, D, Cardona, J, D'Agostino, R, Arshad, T, Samaan, R, Jones, D, Presser, D, Heath, J, Green, S, Bittar, G, Henry, S, Korn, D, Schmedtje, J, Nadar, V, Graham, B, Labroo, A, Clavijo, L, Roseman, H, Ledesma, G, Rosen, R, Dor, I, Kirby, W, Sutton, J, Eder, F, Iteld, B, Gomez-Cortes, J, Buchbinder, M, Kasper, J, Terrelonge, A, Torres, G, Jagielo, T, Alvarez, J, Handelsman, Y, Guillen, M, Richwine, R, Lewy-Alterbaum, L, Corder, C, Arvind, M, Bolshoun, D, Mikhail, M, Minton, S, Alvarado, O, Abbott, J, Cauthen, B, Welter, R, Mintz, R, Cox, J, Quick, A, Weiss, M, Dy, J, Zebrack, J, Gandelman, G, Hegde, V, Silver, M, Degregorio, M, Lawson, W, Paa, C, Bortnick, A, Krolick, M, Sotolongo, R, Cheirif, J, Kumar, P, Jetty, P, Patel, A, Kruk, M, Kobielusz-Gembala, I, Rewerska, B, Madrzejewski, A, Milewski, K, Cygler, J, Petryka-Mazurkiewicz, J, Jastrzebski, W, Korecki, J, Fil, W, Prokopczuk, J, Bochenek, A, Wujkowski, M, Witek, R, Konczakowski, P, Miekus, P, Szczasny, M, Musial, W, Cymerman, K, Lampart, J, Mikosinski, J, Szynal, S, Fares, I, Opolski, G, Mazur, S, Wozakowska-Kaplon, B, Bijata-Bronisz, R, Wierucki, L, Losa, B, Drelich, G, 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C., Istratoaie O., Coman I., Militaru C., Cinteza M., Sinnaeve P. R., Nicolau J. C., Kerr Saraiva J. F., Widimsky P., Kristensen S. D., Hartikainen J., Darius H., Tse H. F., Pais P., Lev E., de Luca L., Ramos Lopez G. A., Kontny F., Babilonia N. A., Zateyshchikov D. A., Ruda M., Elamin O., Kovar F., Dalby A. J., Bueno H., Chiang C. -E., Parkhomenko A., Nguyen T. Q., and Leonsson-Zachrisson M.
- Abstract
Background: Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor. Methods: The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. Eligible patients were randomly assigned (1:1) to either ticagrelor or placebo, by use of an interactive voice-response or web-response system. The THEMIS-PCI trial comprised a prespecified subgroup of patients with previous PCI. The primary efficacy outcome was a composite of cardiovascular death, myocardial infarction, or stroke (measured in the intention-to-treat population). Findings: Between Feb 17, 2014, and May 24, 2016, 11 154 patients (58% of the overall THEMIS trial) with a history of previous PCI were enrolled in the THEMIS-PCI trial. Median follow-up was 3·3 years (IQR 2·8–3·8). In the previous PCI group, fewer patients receiving ticagrelor had a primary efficacy outcome event than in the placebo group (404 [7·3%] of 5558 vs 480 [8·6%] of 5596; HR 0·85 [95% CI 0·74–0·97], p=0·013). The same effect was not observed in patients without PCI (p=0·76, pinteraction=0·16). The proportion of patients with cardiovascular death was similar in both treatment groups (174 [3·1%] with ticagrelor vs 183 (3·3%) with placebo
- Published
- 2019
16. A new snake of the genus Tantilla from west Texas
- Author
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Minton, S A and BioStor
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- 1956
17. PNS261 HOW DOES MACHINE-LEARNING COMPARE TO AN INCOMING MEDICAL STUDENT IN EXTRACTING OUTCOMES RESULTS FROM ABSTRACTS?
- Author
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Michelson, M., primary, Ross, M., additional, and Minton, S., additional
- Published
- 2019
- Full Text
- View/download PDF
18. AI2 LEVERAGING MACHINE-ASSISTANCE TO REPLICATE A SYSTEMATIC REVIEW
- Author
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Michelson, M., primary, Ross, M., additional, and Minton, S., additional
- Published
- 2019
- Full Text
- View/download PDF
19. PNS264 AUTOMATED GENERATION OF EVIDENCE-GAP MAPS FROM MEDICAL LITERATURE
- Author
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Ross, M., primary, Michelson, M., additional, Tee Qiao Ying, A., additional, Ashish, N., additional, and Minton, S., additional
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- 2019
- Full Text
- View/download PDF
20. PNS265 AUTOMATED DISCOVERY OF COMPARATIVE EFFECTIVENESS HYPOTHESES FROM MEDICAL LITERATURE.
- Author
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Ross, M., primary, Michelson, M., additional, Tee Qiao Ying, A., additional, Ashish, N., additional, and Minton, S., additional
- Published
- 2019
- Full Text
- View/download PDF
21. Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial
- Author
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Bohula, Erin A, primary, Scirica, Benjamin M, additional, Inzucchi, Silvio E, additional, McGuire, Darren K, additional, Keech, Anthony C, additional, Smith, Steven R, additional, Kanevsky, Estella, additional, Murphy, Sabina A, additional, Leiter, Lawrence A, additional, Dwyer, Jamie P, additional, Corbalan, Ramon, additional, Hamm, Christian, additional, Kaplan, Lee, additional, Nicolau, Jose Carlos, additional, Ophuis, Ton Oude, additional, Ray, Kausik K, additional, Ruda, Mikhail, additional, Spinar, Jindrich, additional, Patel, Tushar, additional, Miao, Wenfeng, additional, Perdomo, Carlos, additional, Francis, Bruce, additional, Dhadda, Shobha, additional, Bonaca, Marc P, additional, Ruff, Christian T, additional, Sabatine, Marc S, additional, Wiviott, Stephen D, additional, Inzucchi, Silvio, additional, Keech, Anthony, additional, Satlin, Andrew, additional, Brown, Conville, additional, Budaj, Andrzej, additional, Dwyer, Jamie, additional, Garcia-Castillo, Armando, additional, Gupta, Milan, additional, Oude Ophuis, Ton, additional, Ray, Kauski, additional, Weissman, Neil, additional, White, Harvey D, additional, Amerena, J, additional, Arstall, M, additional, Colquhoun, D, additional, Jayasinghe, R, additional, Lee, A, additional, Lehman, R, additional, Moses, R, additional, Proietto, J, additional, Purnell, P, additional, Waites, J, additional, Blombery, P, additional, Cross, D, additional, Worthley, M, additional, d'Emden, M, additional, Selvanayagam, J, additional, Oqueli, RE, additional, Whelan, A, additional, Garrahy, P, additional, de Looze, F, additional, Ninio, D, additional, Horowitz, J, additional, William, M, additional, Suranyi, M, additional, Wittert, G, additional, Le May, M, additional, Pandey, AS, additional, Vizel, S, additional, Labonte, R, additional, Beaudry, Y, additional, Fortin, C, additional, Bell, A, additional, Kouz, S, additional, St-Amour, É, additional, Bata, I, additional, St Maurice, F, additional, Chehayeb, R, additional, Constance, C, additional, Wong, G, additional, Hess, A, additional, Liutkus, J, additional, Poirier, P, additional, Teitelbaum, I, additional, Berlingieri, J, additional, Cha, J, additional, Hartleib, M, additional, Heffernan, M, additional, Twum-Barima, D, additional, Pandith, V, additional, Aronson, R, additional, Goldenberg, R, additional, Ajala, B, additional, Jain, A, additional, Ross, S, additional, Bajaj, H, additional, Khandwala, H, additional, Yared, Z, additional, Gupta, N, additional, Bédard, J, additional, Wharton, S, additional, Blouin, F, additional, Savard, D, additional, Shukla, D, additional, Cobos, J, additional, Godoy, G, additional, Perez, L, additional, Pincetti, C, additional, Saavedra Guajardo, V, additional, Varleta, P, additional, Conejeros, C, additional, Lanas, F, additional, Bayram Llamas, E, additional, Cardona Muñoz, E, additional, Garcia, R, additional, Garza Ruiz, J, additional, Llamas Esperon, G, additional, Lopez Rosas, E, additional, Melendez Mier, G, additional, Ramos, G, additional, Hart, H, additional, Scott, D, additional, Ternouth, I, additional, Benatar, J, additional, Elliott, J, additional, Cutfield, R, additional, Manning, P, additional, Williams, M, additional, Ferrier, K, additional, Scott, R, additional, Wilson, S, additional, Leikis, R, additional, Nirmalaraj, BK, additional, Krzyżagórska, E, additional, Miękus, P, additional, Bronisz, M, additional, Mirek-Bryniarska, E, additional, Łanda, K, additional, Stasiewski, A, additional, Żechowicz, T, additional, Zytkiewicz-Jaruga, D, additional, Korecki, J, additional, Ogórek, M, additional, Pawłowicz, L, additional, Piepiorka, M, additional, Skierkowska, J, additional, Stankiewicz, A, additional, Szyprowska, E, additional, Witek, R, additional, Bochenek, A, additional, Kończakowski, P, additional, Wojnowski, Ł, additional, Wujkowski, M, additional, Cymerman, K, additional, Korzeniak, R, additional, Mąder, P, additional, Mikłaszewicz, B, additional, Stachlewski, P, additional, Goch, A, additional, Pomiećko, W, additional, Skórski, M, additional, Romanowski, L, additional, Jusiak, K, additional, Laskowska-Derlaga, E, additional, Bijata-Bronisz, R, additional, Kaźmierczak, J, additional, Goldberg, R, additional, Henderson, D, additional, Korban, E, additional, Rohr, K, additional, Claxton, E, additional, Weiss, R, additional, Angiolillo, D, additional, Boccalandro, F, additional, Chu, K, additional, Thorn, E, additional, Randhawa, P, additional, Singh, N, additional, Bittar, G, additional, Guarnieri, T, additional, Saeed, S, additional, Sharma, S, additional, Shepard, M, additional, French, W, additional, Desai, P, additional, Bernstein, R, additional, Rogers, W, additional, Singal, R, additional, Schneider, R, additional, Shanes, J, additional, Ong, S, additional, Condit, J, additional, Donahoe, S, additional, Brill, D, additional, Einhorn, D, additional, Ebrahimi, R, additional, Labroo, A, additional, Graf, R, additional, Scott, J, additional, Hoekstra, J, additional, Jetty, P, additional, Luckasen, G, additional, O'Donnell, P, additional, Gonte, W, additional, Pomposini, D, additional, Quadrel, M, additional, Koren, M, additional, Schlager, D, additional, Schramm, E, additional, Singal, D, additional, Lupovitch, S, additional, Soni, A, additional, Seigel, P, additional, Roberts, J, additional, Soufer, J, additional, Reza, S, additional, Quinlan, E, additional, Moretto, T, additional, First, B, additional, Khan, M, additional, Chilka, S, additional, Colfer, H, additional, Teklinski, A, additional, Wallace-Wilding, K, additional, Ellison, H, additional, Muse, D, additional, Aronoff, S, additional, Higgins, A, additional, Patel, S, additional, Elinoff, V, additional, Karim, A, additional, Awasty, V, additional, Chuang, R, additional, Roseman, H, additional, Dugano-Daphnis, P, additional, Albert, M, additional, Sheikh, K, additional, Bays, H, additional, Kaster, S, additional, Goldstein, M, additional, Rubino, D, additional, Calatayud, G, additional, Snyder, H, additional, Williams, T, additional, Hershon, K, additional, Hagan, M, additional, Isserman, S, additional, Kahn, B, additional, Anderson, J, additional, Gimness, MP, additional, Raisinghani, A, additional, Christina, M, additional, Raikhel, M, additional, Gillespie, E, additional, Portnay, E, additional, Heiman, M, additional, Qureshi, M, additional, Lee, J, additional, Blonder, R, additional, Cucher, F, additional, Miller, G, additional, Kotlaba, D, additional, Cornett, G, additional, Beavins, J, additional, Augenbraun, C, additional, Reinhardt, S, additional, Bartkowiak, A, additional, Salacata, A, additional, Blevins, T, additional, Benjamin, S, additional, Diener, J, additional, George, W, additional, Barker, B, additional, Richwine, R, additional, Baldari, D, additional, Alfieri, A, additional, Barreto, A, additional, Zhang, L, additional, Shah, R, additional, Hendrix, E, additional, Subramaniyam, V, additional, Hurley, S, additional, Lillestol, M, additional, O'Donoghue, M, additional, Shayani, S, additional, Ryan, E, additional, Call, R, additional, Zemel, L, additional, Chang, A, additional, Kivitz, A, additional, Freyne, B, additional, Bland, V, additional, Shore, K, additional, Mostel, E, additional, Uzoaga, E, additional, Andrawis, N, additional, Gabra, N, additional, Ghitis, A, additional, Sabatino, K, additional, Browder, D, additional, Varma, S, additional, Smith, S, additional, Fink, R, additional, Aycock, GR, additional, Doty, WD, additional, Alfonso, T, additional, Eshaghian, S, additional, Karlsberg, R, additional, Zarich, S, additional, Landau, C, additional, McKenzie, M, additional, Krause, R, additional, Davis, W, additional, Haddad, T, additional, Voyce, S, additional, Alford, C, additional, LeDoux, J, additional, O'Dea, D, additional, Park, J, additional, Aroda, V, additional, Getaneh, A, additional, Graham, B, additional, Bhagwat, R, additional, Korn, D, additional, Ruoff, G, additional, Wiseman, A, additional, Lieber, I, additional, Fialkow, J, additional, Gonzalez-Campoy, JM, additional, Bayron, C, additional, Bertolet, B, additional, Lash, J, additional, Gerrish, C, additional, Robertson, D, additional, Rosenfeld, J, additional, Seidner, M, additional, Agaiby, J, additional, Silverfield, J, additional, Sugimoto, D, additional, Lubin, B, additional, Alhaddad, M, additional, Lui, H, additional, Lakin, G, additional, Chokshi, S, additional, Donovan, D, additional, Felten, W, additional, Minton, S, additional, Kimmelstiel, C, additional, Kuvin, J, additional, Still, C, additional, Byars, W, additional, Talano, J, additional, Desai, V, additional, Bradley, AJ, additional, Baker, S, additional, Chane, M, additional, Mercado, A, additional, Baron, S, additional, Harris, B, additional, Mayer, N, additional, Concha, M, additional, Carr, K, additional, Chaykin, L, additional, Willis, J, additional, Clay, A, additional, Fenstad, E, additional, Furda, J, additional, Peterson, P, additional, Chang, M, additional, Aronne, L, additional, Jones, D, additional, Prashad, R, additional, Benson, M, additional, Stegemoller, R, additional, Longshaw, K, additional, Saleh, J, additional, Jennings, W, additional, Detweiler, R, additional, Viswanath, D, additional, Patel, R, additional, Lederman, S, additional, Weinstein, D, additional, Korabathina, R, additional, Singh, V, additional, Rosen, J, additional, Estevez, R, additional, Levin, P, additional, McNeill, R, additional, Kalen, V, additional, Reed, J, additional, Ashley, R, additional, Herman, L, additional, Tsai, Y, additional, Kayne, D, additional, White, A, additional, Hussain, I, additional, Tami, L, additional, Cohen, K, additional, Robinson, J, additional, Fuchs-Ertman, D, additional, Platt, G, additional, Belardo, L, additional, Reddy, R, additional, Rosendorff, C, additional, Saba, F, additional, Powell, S, additional, Anderson, K, additional, Abidi, M, additional, Rezkalla, S, additional, Paraschos, A, additional, Wilson, J, additional, Moursi, M, additional, Shah, A, additional, Nadar, V, additional, Stonesifer, L, additional, Bialow, M, additional, Cannon, K, additional, Ellison, W, additional, Stedman, M, additional, Brown, J, additional, Harper, W, additional, Lucas, KJ, additional, DiGiovanna, M, additional, Rodbard, H, additional, Biscoveanu, M, additional, Davis, C, additional, Hall, J, additional, Littlefield, R, additional, Gorman, T, additional, Kereiakes, D, additional, Chang, FM, additional, Tatu, H, additional, Cheung, D, additional, Kaine, J, additional, Knutson, T, additional, Logemann, T, additional, Pueblitz, G, additional, Bianco, J, additional, Henson, B, additional, Neustel, M, additional, Gelernt, M, additional, Nelson, W, additional, Moriarty, K, additional, Lefebvre, G, additional, Maw, K, additional, Rink, L, additional, Behn, P, additional, Studdard, H, additional, Argoud, G, additional, O'Connor, T, additional, Krichmar, P, additional, Raad, G, additional, Pereles-Ortiz, J, additional, Sorli, C, additional, Cohen, A, additional, Pettis, K, additional, Cavanaugh, B, additional, Phillips, C, additional, Wahlen, J, additional, Radin, D, additional, Rider, J, additional, Kosinski, E, additional, Leimbach, W, additional, Odhav, A, additional, Hakas, J, additional, Tan, A, additional, Howell, M, additional, Wombolt, D, additional, Fishman, N, additional, Shah, P, additional, Wylie, P, additional, Arauz-Pacheco, C, additional, Cavale, A, additional, George, A, additional, Kroll, R, additional, Krantzler, J, additional, Tahirkheli, N, additional, Jabro, M, additional, Newell, M, additional, Mullen, P, additional, Gencheff, N, additional, Meli, J, additional, Vora, K, additional, Kotek, L, additional, Pyzdrowski, K, additional, Paez, H, additional, Moran, J, additional, Tannenbaum, A, additional, Deck, K, additional, Busch, R, additional, Levinson, L, additional, Azizad, M, additional, Whitaker, J, additional, Fox, B, additional, Huffman, C, additional, Ashraf, M, additional, Diogo, J, additional, Kushner, R, additional, Tallet, J, additional, Channamsetty, V, additional, Suh, D, additional, Atieh, M, additional, Navas, J, additional, Young, V, additional, Shaw, S, additional, Dor, I, additional, Duffy, B, additional, Rubin, P, additional, Lewis, D, additional, Kaye, W, additional, Benton, R, additional, Burbano, J, additional, Hotchkiss, D, additional, Magno, A, additional, Alberton, A, additional, Collins, J, additional, Alvarado, O, additional, Stich, M, additional, Mahal, S, additional, Liu, J, additional, Hong, M, additional, Dy, J, additional, Block, B, additional, Lamantia, J, additional, Pritchard, J, additional, Davis, M, additional, Srivastava, S, additional, Bilazarian, S, additional, Rosario, R, additional, McCartney, M, additional, Blumberg, V, additional, Rajan, R, additional, Martin, E, additional, Wright, S, additional, Brinson, C, additional, Johnston, J, additional, Graves, M, additional, Dominguez, M, additional, McKenzie, W, additional, Abadier, R, additional, Tran, C, additional, Castello, R, additional, Morawski, E, additional, White, J, additional, Morris, F, additional, Perez, A, additional, Trueba, P, additional, Sanchez, M, additional, Andersen, J, additional, Kastelic, R, additional, Khan, J, additional, Rodriguez, H, additional, Izquierdo, W, additional, Matias, A, additional, Essandoh, L, additional, and Ince, C, additional
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- 2018
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22. Abstract GS4-01: Pooled analysis of five randomized trials investigating temporary ovarian suppression with gonadotropin-releasing hormone analogs during chemotherapy as a strategy to preserve ovarian function and fertility in premenopausal early breast cancer patients
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Lambertini, M, primary, Moore, HCF, additional, Leonard, RCF, additional, Loibl, S, additional, Munster, P, additional, Bruzzone, M, additional, Boni, L, additional, Unger, JM, additional, Anderson, RA, additional, Mehta, K, additional, Minton, S, additional, Poggio, F, additional, Albain, KS, additional, Adamson, DJA, additional, Gerber, B, additional, Cripps, A, additional, Bertelli, G, additional, Seiler, S, additional, Ceppi, M, additional, Partridge, AH, additional, and Del Mastro, L, additional
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- 2018
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23. Common Antigens in Snake Venoms
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Minton, S. A., Jr. and Lee, Chen-Yuan, editor
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- 1979
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24. Sentinel node biopsy prior to neoadjuvant chemotherapy for determining axillary status and treatment prognosis in locally advanced breast cancer
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Cox, C., Furman, B. T., Stowell, N. G., White, L. B., Clark, J. D., Dupont, E. L., and Minton, S. B.
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- 2004
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25. PC-based web authoring: How to learn as little unix as possible while getting on the Web
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Gennari, L.T., primary, Breaux, M., additional, Minton, S., additional, and McDunn, R., additional
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- 1996
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26. No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease
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Murray, Joseph A., primary, Kelly, Ciarán P., additional, Green, Peter H.R., additional, Marcantonio, Annette, additional, Wu, Tsung-Teh, additional, Mäki, Markku, additional, Adelman, Daniel C., additional, Ansari, S., additional, Ayub, K., additional, Basile, A., additional, Behrend, C., additional, Bercik, P., additional, Bressler, B., additional, Byrnes, V., additional, Chandan, V.S., additional, Cheekati, V., additional, Chipps, B., additional, Coates, A., additional, Collatrella, A., additional, Condemi, J., additional, Corder, C., additional, Corren, J., additional, Curtis, C., additional, DeMeo, M., additional, Desta, T., additional, Devereaux, C., additional, DiMarino, A., additional, DuPree, M., additional, Ennis, C., additional, Fedorak, R., additional, Fogel, R., additional, Freeman, S., additional, Freilich, B., additional, Friedenberg, K., additional, Geenen, D., additional, Gill, K., additional, Goldsobel, A., additional, Goldstein, J., additional, Goldstein, M., additional, Gordon, G., additional, Hardi, R., additional, Harris, L., additional, Holmes, R., additional, Jagarlamundi, K., additional, James, G., additional, Kaplan, M., additional, Kirstein, J., additional, Knoll, A., additional, Kotfila, R., additional, Krause, R., additional, Kravitz, A., additional, Kreines, M., additional, Lähdeaho, M.L., additional, Lamet, M., additional, Laskin, K., additional, Lebwohl, B., additional, Leffler, D., additional, Lewis, S., additional, Liakos, S., additional, Lundin, K., additional, Marks, K., additional, Merkes, K., additional, Minton, S., additional, Moussa, S., additional, Narayen, V., additional, Nehra, V., additional, Newton, E., additional, Nyberg, A., additional, Oosthuizen, J., additional, Otrok, T., additional, Patel, D., additional, Pepin, C., additional, Phillips, R., additional, Pyle, G., additional, Reichelderfer, M., additional, Reid, B., additional, Ritter, T., additional, Saini, S., additional, Sanders, D., additional, Schulman, M., additional, Semrad, C., additional, Shah, S., additional, Stockwell, D., additional, Strout, C., additional, Suez, D., additional, Tatum, H., additional, Torbenson, M.S., additional, Turner, M., additional, Varunok, P., additional, Vazquez-Roque, M., additional, Vento, A., additional, Welton, T., additional, Wohlman, R., additional, Wood, M., additional, Woods, S., additional, and Yousef, K., additional
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- 2017
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27. Abstract P6-11-04: The evaluation of ganitumab/metformin plus standard neoadjuvant therapy in high-risk breast cancer: Results from the I-SPY 2 trial
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Yee, D, primary, Paoloni, M, additional, van't Veer, L, additional, Sanil, A, additional, Yau, C, additional, Forero, A, additional, Chien, AJ, additional, Wallace, AM, additional, Moulder, S, additional, Albain, KS, additional, Kaplan, HG, additional, Elias, AD, additional, Haley, BB, additional, Boughey, JC, additional, Kemmer, KA, additional, Korde, LA, additional, Isaacs, C, additional, Minton, S, additional, Nanda, R, additional, DeMichele, A, additional, Lang, JE, additional, Buxton, MB, additional, Hylton, NM, additional, Symmans, WF, additional, Lyandres, J, additional, Hogarth, M, additional, Perlmutter, J, additional, Esserman, LJ, additional, and Berry, DA, additional
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- 2017
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28. Abstract P6-11-02: Efficacy of Hsp90 inhibitor ganetespib plus standard neoadjuvant therapy in high-risk breast cancer: Results from the I-SPY 2 trial
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Forero, A, primary, Yee, D, additional, Buxton, MB, additional, Symmans, WF, additional, Chien, AJ, additional, Boughey, JC, additional, Elias, AD, additional, DeMichele, A, additional, Moulder, S, additional, Minton, S, additional, Kaplan, HG, additional, Albain, KS, additional, Wallace, AM, additional, Haley, BB, additional, Isaacs, C, additional, Korde, LA, additional, Nanda, R, additional, Lang, JE, additional, Kemmer, KA, additional, Hylton, NM, additional, Paoloni, M, additional, van't Veer, L, additional, Lyandres, J, additional, Perlmutter, J, additional, Hogarth, M, additional, Yau, C, additional, Sanil, A, additional, Berry, DA, additional, and Esserman, LJ, additional
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- 2017
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29. Abstract OT3-02-14: A phase 1 study in patients with metastatic breast cancer to evaluate the feasibility of magnetic resonance imaging with ferrumoxytol as a potential biomarker for response to treatment with nanoliposomal irinotecan (nal-IRI, MM-398)
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Sachdev, JC, primary, Ramanathan, RK, additional, Raghunand, N, additional, Anders, C, additional, Munster, P, additional, Minton, S, additional, Northfelt, D, additional, Blanchette, S, additional, Campbell, K, additional, Lee, H, additional, Klinz, SG, additional, Hendriks, BS, additional, Moyo, V, additional, Fitzgerald, JB, additional, and Korn, RL, additional
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- 2016
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30. Interactive Data Integration through Smart Copy & Paste
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Ives, Z. G., Knoblock, C. A., Minton, S., Jacob, M., Talukdar, P. P., Tuchinda, R., Jose Luis Ambite, Muslea, M., and Gazen, C.
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FOS: Computer and information sciences ,Artificial Intelligence (cs.AI) ,Computer Science - Databases ,Computer Science - Artificial Intelligence ,Databases (cs.DB) - Abstract
In many scenarios, such as emergency response or ad hoc collaboration, it is critical to reduce the overhead in integrating data. Ideally, one could perform the entire process interactively under one unified interface: defining extractors and wrappers for sources, creating a mediated schema, and adding schema mappings ? while seeing how these impact the integrated view of the data, and refining the design accordingly. We propose a novel smart copy and paste (SCP) model and architecture for seamlessly combining the design-time and run-time aspects of data integration, and we describe an initial prototype, the CopyCat system. In CopyCat, the user does not need special tools for the different stages of integration: instead, the system watches as the user copies data from applications (including the Web browser) and pastes them into CopyCat?s spreadsheet-like workspace. CopyCat generalizes these actions and presents proposed auto-completions, each with an explanation in the form of provenance. The user provides feedback on these suggestions ? through either direct interactions or further copy-and-paste operations ? and the system learns from this feedback. This paper provides an overview of our prototype system, and identifies key research challenges in achieving SCP in its full generality., Comment: CIDR 2009
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- 2009
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31. Common Antigens in Snake Venoms
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Minton, S. A., primary
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- 1979
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32. Ablation of MEKK4 Kinase Activity Causes Neurulation and Skeletal Patterning Defects in the Mouse Embryo
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Johnson, G. L., Winter-Vann, A. M., Uhlik, M. T., Johnson, N. L., Cuevas, B. D., Sather, S., Nakamura, K., Vaillancourt, R. R., Heasley, L. E., Magnuson, T., Rivera-Perez, J. A., Lauder, J. M., Abell, A. N., and Minton, S. K.
- Abstract
Skeletal disorders and neural tube closure defects represent clinically significant human malformations. The signaling networks regulating normal skeletal patterning and neurulation are largely unknown. Targeted mutation of the active site lysine of MEK kinase 4 (MEKK4) produces a kinase-inactive MEKK4 protein (MEKK4K1361R). Embryos homozygous for this mutation die at birth as a result of skeletal malformations and neural tube defects. Hindbrains of exencephalic MEKK4K1361R embryos show a striking increase in neuroepithelial cell apoptosis and a dramatic loss of phosphorylation of MKK3 and -6, mitogen-activated protein kinase kinases (MKKs) regulated by MEKK4 in the p38 pathway. Phosphorylation of MAPK-activated protein kinase 2, a p38 substrate, is also inhibited, demonstrating a loss of p38 activity in MEKK4K1361R embryos. In contrast, the MEK1/2-extracellular signal-regulated kinase 1 (ERK1)/ERK2 and MKK4-Jun N-terminal protein kinase pathways were unaffected. The p38 pathway has been shown to regulate the phosphorylation and expression of the small heat shock protein HSP27. Compared to the wild type, MEKK4K1361R fibroblasts showed significantly reduced phosphorylation of p38 and HSP27, with a corresponding heat shock-induced instability of the actin cytoskeleton. Together, these data demonstrate MEKK4 regulation of p38 and that substrates downstream of p38 control cellular homeostasis. The findings are the first demonstration that MEKK4-regulated p38 activity is critical for neurulation.
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- 2005
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33. Planning with Templates
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Dyer, D, Cross, S, Knoblock, C.A, Minton, S, and Tate, Austin
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Informatics ,templates ,Computer Science ,Artificial Intelligence Applications Institute ,artificial intelligence - Abstract
The University of Edinburgh and research sponsors are authorised to reproduce and distribute reprints and on-line copies for their purposes notwithstanding any copyright annotation hereon. The views and conclusions contained herein are the authorâ s and shouldnâ t be interpreted as necessarily representing the official policies or endorsements, either expressed or implied, of other parties. When we talk about planning with templates,we mean standard operating procedures we've learned or been trained to use for solving typical problems and as a starting point for solving novel problems. These structures contain variables relevant to an activity and current variable values that affect a problem or have been chosen in a problem-solving instance. With templates we can configure domain-independent planning algorithms, making them applicable to many different problem domains. By making the template explicit for the user in the form of a GUI, we can facilitate mixed-initiative, user-centric systems that help maintain awareness of complex and dynamic situations, share information across the network, and solve problems incrementally and iteratively.
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- 2005
34. Why do four NICUs using identical RBC transfusion guidelines have different gestational age-adjusted RBC transfusion rates?
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Henry, E, primary, Christensen, R D, additional, Sheffield, M J, additional, Eggert, L D, additional, Carroll, P D, additional, Minton, S D, additional, Lambert, D K, additional, and Ilstrup, S J, additional
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- 2014
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35. Abstract P6-06-31: Prognostic factors and outcomes in triple negative breast cancer - A single institution experience
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Apuri, S, primary, Sun, W, additional, Bardhan, P, additional, Minton, S, additional, Soliman, H, additional, Han, HS, additional, Lee, J-H, additional, Fulp, W, additional, and Ismail-Khan, R, additional
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- 2013
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36. Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer
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Zheng, X Q, primary, Guo, J P, additional, Yang, H, additional, Kanai, M, additional, He, L L, additional, Li, Y Y, additional, Koomen, J M, additional, Minton, S, additional, Gao, M, additional, Ren, X B, additional, Coppola, D, additional, and Cheng, J Q, additional
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- 2013
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37. 1202 ORAL A Phase I Study of the Potent AKT Inhibitor MK-2206 in Combination With Carboplatin and Paclitaxel, Docetaxel or Erlotinib in Patients With Advanced Solid Tumours
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Molife, L.R., primary, Minton, S., additional, Vitfell-Pedersen, J., additional, Chen, E., additional, Sullivan, D., additional, Yan, L., additional, Zernhelt, A.M., additional, Siu, L., additional, de Bono, J.S., additional, and Tolcher, A.W., additional
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- 2011
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38. A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer
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Munster, P N, primary, Thurn, K T, additional, Thomas, S, additional, Raha, P, additional, Lacevic, M, additional, Miller, A, additional, Melisko, M, additional, Ismail-Khan, R, additional, Rugo, H, additional, Moasser, M, additional, and Minton, S E, additional
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- 2011
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39. A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.
- Author
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Minton, S. E., primary, LoRusso, P., additional, Lockhart, A. C., additional, Saif, M., additional, Krishnamurthi, S. S., additional, Pickett-Gies, C. A., additional, Wang, Y., additional, Guan, S., additional, Roben, E., additional, and Stein, M. N., additional
- Published
- 2010
- Full Text
- View/download PDF
40. Neoadjuvant Intratumoral Injection of Dendritic Cells in Breast Cancer.
- Author
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Minton, S., primary, Gabrilovich, D., additional, Lacevic, M., additional, Laronga, C., additional, Lee, M., additional, Kiluk, J., additional, Khakpour, N., additional, Bui, M., additional, Soliman, H., additional, Ismail-khan, R., additional, Han, H., additional, Munster, P., additional, Janssen, W., additional, Cowan, K., additional, Talmadge, J., additional, and Reed, E., additional
- Published
- 2009
- Full Text
- View/download PDF
41. Clinical Phase II Study of Vorinostat, a Hydroxamic Type Histone Deacetylase Inhibitor, in Combination with Tamoxifen To Reverse Acquired Hormone Resistance in Breast Cancer Patients Who Progressed on Hormone Therapy.
- Author
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Munster, P., primary, Lacevic, M., additional, Thomas, S., additional, Ismail-Khan, R., additional, Rugo, H., additional, Melisko, M., additional, and Minton, S., additional
- Published
- 2009
- Full Text
- View/download PDF
42. Phase II trial of the histone deacetylase inhibitor, vorinostat, to restore hormone sensitivity to the antiestrogen tamoxifen in patients with advanced breast cancer who progressed on prior hormone therapy
- Author
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Munster, P. N., primary, Lacevic, M., additional, Thomas, S., additional, Christian, C., additional, Ismail-Khan, R., additional, Melisko, M., additional, Rugo, H., additional, and Minton, S. E., additional
- Published
- 2009
- Full Text
- View/download PDF
43. Male breast cancer: follow-up recommendations after surgery.
- Author
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Laronga, C, primary, Lee, MC, additional, Park, CK, additional, Kiluk, J, additional, Meade, T, additional, Boulware, D, additional, Minton, S, additional, and Harris, E, additional
- Published
- 2009
- Full Text
- View/download PDF
44. Evaluation of the SSRCS engine with hydrazine as a fuel, phase 2
- Author
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Minton, S. J
- Subjects
Propellants And Fuels - Abstract
Test firing of the Space Shuttle Reaction Control Thruster (SSRCT) was conducted to determine the characteristic velocity and chamber throat temperatures when the fuel is changed from monomethylhydrazine (MMH) to hydrazine. Thruster performance with hydrazine was essentially as predicted. Characteristic velocity at a mixture ratio of 1.4 (equal volumetric flow) for hydrazine was 5180 feet/second compared with 5110 feet/second at a mixture of 1.6 for MMH. Specific impulse with 22:1 nozzle is calculated to be 280 lbf-sec/lbm. Thermal performance, as measured by chamber throat temperature, was dramatically different (colder) than predicted. Throat temperatures of 2330 F were predicted from a cooling model which assumed a reactive liquid cooling film. Throat temperatures of 800 - 1000 F were measured. An attempt to reconcile the differences between film cooling predictions and the measurements, indicated that an evaporation (nonreactive fluid) model rather than a decomposition (reactive fluid) model best fits the test data at 0/F = 1.4. At higher mixture ratios, a transition to temperatures typical of the reactive fluid model were observed.
- Published
- 1978
45. Evaluation of the SSRCT engine with a hydrazine as a fuel, phase 1
- Author
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Minton, S. J
- Subjects
Spacecraft Propulsion And Power - Abstract
The performance parameters for the space shuttle reaction control thruster (SSRCT) when the fuel is changed from monomethylhydrazine to hydrazine were predicted. Potential problems are higher chamber wall temperature during steady state operation and explosive events during pulse mode operation. Solutions to the problems are suggested. To conduct the analysis, a more realistic film cooling model was devised which considers that hydrazine based fuels are reactive when used as a film coolant on the walls of the combustion chamber. Hydrazine based fuels can decompose exothermally as a monopropellant and also enter into bipropellant reactions with any excess oxidizer in the combustion chamber. It is concluded that the conversion of the thruster from MMH to hydrazine fuel is feasible but that a number of changes would be required to achieve the same safety margins as the monomethylhydrazine-fueled thruster.
- Published
- 1978
46. Phase II trial of vorinostat, a histone deacetylase inhibitor to restore the hormone sensitivity to the anti-estrogen tamoxifen in patients with advanced breast cancer having failed prior aromatase inhibitor therapy
- Author
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Munster, P. N., primary, Lacevic, M., additional, Schmitt, M., additional, Bicaku, E., additional, Marchion, D., additional, Stephens, A., additional, Sullivan, L., additional, and Minton, S., additional
- Published
- 2008
- Full Text
- View/download PDF
47. Preservation of ovarian function in young women treated with neoadjuvant chemotherapy for breast cancer: A randomized trial using the GnRH agonist (triptorelin) during chemotherapy
- Author
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Ismail-Khan, R., primary, Minton, S., additional, Cox, C., additional, Sims, I., additional, Lacevic, M., additional, Gross-King, M., additional, Xu, P., additional, Carter, B., additional, and Munster, P. N., additional
- Published
- 2008
- Full Text
- View/download PDF
48. Phase I trial of a sequence-specific combination of the HDAC inhibitor, vorinostat (SAHA) followed by doxorubicin in advanced solid tumor malignancies
- Author
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Daud, A., primary, Schmitt, M., additional, Marchion, D., additional, Bicaku, E., additional, Minton, S., additional, Egorin, M., additional, Zwiebel, J., additional, Chiappori, A., additional, Sullivan, D., additional, and Munster, P., additional
- Published
- 2007
- Full Text
- View/download PDF
49. Phase I/II trial combining the HDAC inhibitor, valproic acid (VPA) and FEC100 (5-fluorouracil, epirubicin and cyclophosphamide) in locally advanced/metastatic breast cancer
- Author
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Munster, P. N., primary, Marchion, D. C., additional, Schmitt, M., additional, Bicaku, E., additional, Lacevic, M., additional, Minton, S., additional, Carter, W., additional, and Daud, A., additional
- Published
- 2007
- Full Text
- View/download PDF
50. Active Learning with Multiple Views
- Author
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Muslea, I., primary, Minton, S., additional, and Knoblock, C. A., additional
- Published
- 2006
- Full Text
- View/download PDF
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