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198 results on '"Mirabile, Lorenzo"'

22. Combined Surgical and Endoscopic Approach for Ring–Sling Complex.

Author

Porcedda, Giulio, Brambilla, Alice, Favilli, Silvia, Murzi, Bruno, Mirabile, Lorenzo, Baggi, Roberto, and Arcieri, Luigi

Subjects
BRONCHOSCOPY, CONGENITAL heart disease, PULMONARY artery, EARLY death, TRACHEAL stenosis
Abstract

Background Left pulmonary artery (LPA) sling (PAS) is a vascular ring, which is frequently associated with long-segment tracheal stenosis (TS). Mortality rate in operated children is still high, especially in cases of severe tracheal hypoplasia and/or associated congenital heart defects (CHDs). We report our experience of treatment and follow-up in a pediatric cohort of patients affected by PAS with severe tracheobronchial involvement. Methods From 2005 to 2017, we enrolled 11 children diagnosed with PAS and congenital TS requiring surgical intervention. Echocardiography, computed tomography, and bronchoscopy were performed in all patients. Associated CHD were present in 5 (45%) patients. Tracheal reconstruction techniques included slide tracheoplasty (7/11; 63%), slide tracheoplasty and costal cartilage graft (2/11; 18%), and Hazekamp technique (2/11; 18%). Nine patients underwent LPA direct reimplantation and concomitant tracheoplasty; concomitant surgical repair for CHD was performed in three children. Results Over a mean follow-up of 30 months (range: 3–75 months), a late mortality of 18% was registered; no early death occurred. Good flow through LPA could be documented in all patients. Ten children required operative bronchoscopies (mean: 16/patients) aimed at stent positioning/removal, treatment of granulomas, and tracheobronchial dilatation. Conclusions Severe tracheobronchial stenosis and associated CHD were the main determinants for hospitalization time, intensive assistance, and repeated endoscopic procedures. Patients affected by PAS/TS complex require a careful management at high-specialized centers providing multidisciplinary team. Respiratory endoscopy may play a central role both in preoperatory assessment and in postoperative management of patients showing severe tracheobronchial involvement. [ABSTRACT FROM AUTHOR]

Published
2020
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23. Tracheal surgery in children: outcome of a 12-year survey

Author

Arcieri, Luigi, primary, Pak, Vitali, additional, Poli, Vincenzo, additional, Baggi, Roberto, additional, Serio, Paola, additional, Assanta, Nadia, additional, Moschetti, Riccardo, additional, Noccioli, Bruno, additional, De Masi, Salvatore, additional, Mirabile, Lorenzo, additional, and Murzi, Bruno, additional

Published
2017
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27. Double Tracheoesophageal Fistula and Azygos Lobe

Author

De Carolis, Maria Pia, primary, Cocca, Carmen, additional, Cota, Francesco, additional, Pinna, Giovanni, additional, Rubortone, Serena Antonia, additional, Romagnoli, Costantino, additional, Mirabile, Lorenzo, additional, and Serio, Paola, additional

Published
2016
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28. Efficacy of ketamine in refractory convulsive status epilepticus in children: A protocol for a sequential design, multicentre, randomised, controlled, open-label, non-profit trial (KETASER01)

Author

Rosati, Anna, Ilvento, Lucrezia, L'Erario, Manuela, Masi, Salvatore De, Biggeri, Annibale, Fabbro, Giancarlo, Bianchi, Roberto, Stoppa, Francesca, Fusco, Lucia, Pulitano', Silvia Maria, Battaglia, Domenica Immacolata, Pettenazzo, Andrea, Sartori, Stefano, Biban, Paolo, Fontana, Elena, Cesaroni, Elisabetta, Mora, Donatella, Costa, Paola, Meleleo, Rosanna, Vittorini, Roberta, Conio, Alessandra, Wolfler, Andrea, Mastrangelo, Massimo, Mondardini, Maria Cristina, Franzoni, Emilio, Mcgreevy, Kathleen S., Simone, Lorena Di, Pugi, Alessandra, Mirabile, Lorenzo, Vigevano, Federico, Guerrini, Renzo, Pulitanò,Silvia Maria Modesta (ORCID:0000-0002-8496-379X), Battaglia, Domenica (ORCID:0000-0003-0491-4021), Rosati, Anna, Ilvento, Lucrezia, L'Erario, Manuela, Masi, Salvatore De, Biggeri, Annibale, Fabbro, Giancarlo, Bianchi, Roberto, Stoppa, Francesca, Fusco, Lucia, Pulitano', Silvia Maria, Battaglia, Domenica Immacolata, Pettenazzo, Andrea, Sartori, Stefano, Biban, Paolo, Fontana, Elena, Cesaroni, Elisabetta, Mora, Donatella, Costa, Paola, Meleleo, Rosanna, Vittorini, Roberta, Conio, Alessandra, Wolfler, Andrea, Mastrangelo, Massimo, Mondardini, Maria Cristina, Franzoni, Emilio, Mcgreevy, Kathleen S., Simone, Lorena Di, Pugi, Alessandra, Mirabile, Lorenzo, Vigevano, Federico, Guerrini, Renzo, Pulitanò,Silvia Maria Modesta (ORCID:0000-0002-8496-379X), and Battaglia, Domenica (ORCID:0000-0003-0491-4021)

Abstract

Introduction: Status epilepticus (SE) is a lifethreatening neurological emergency. SE lasting longer than 120 min and not responding to first-line and second-line antiepileptic drugs is defined as 'refractory' (RCSE) and requires intensive care unit treatment. There is currently neither evidence nor consensus to guide either the optimal choice of therapy or treatment goals for RCSE, which is generally treated with coma induction using conventional anaesthetics (high dose midazolam, thiopental and/or propofol). Increasing evidence indicates that ketamine (KE), a strong N-methyl-D-aspartate glutamate receptor antagonist, may be effective in treating RCSE. We hypothesised that intravenous KE is more efficacious and safer than conventional anaesthetics in treating RCSE. Methods and analysis: A multicentre, randomised, controlled, open-label, non-profit, sequentially designed study will be conducted to assess the efficacy of KE compared with conventional anaesthetics in the treatment of RCSE in children. 10 Italian centres/ hospitals are involved in enrolling 57 patients aged 1 month to 18 years with RCSE. Primary outcome is the resolution of SE up to 24 hours after withdrawal of therapy and is updated for each patient treated according to the sequential method. Ethics and dissemination: The study received ethical approval from the Tuscan Paediatric Ethics Committee (12/2015). The results of this study will be published in peer-reviewed journals and presented at international conferences.

Published
2016

29. Residual tracheobronchial malacia after surgery for vascular compression in children: treatment with stenting†

Author

Serio, Paola, primary, Nenna, Raffaella, additional, Fainardi, Valentina, additional, Grisotto, Laura, additional, Biggeri, Annibale, additional, Leone, Roberto, additional, Arcieri, Luigi, additional, Di Maurizio, Marco, additional, Colosimo, Denise, additional, Baggi, Roberto, additional, Murzi, Bruno, additional, Mirabile, Lorenzo, additional, and Midulla, Fabio, additional

Published
2016
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33. Efficacy of ketamine in refractory convulsive status epilepticus in children: a protocol for a sequential design, multicentre, randomised, controlled, open-label, non-profit trial (KETASER01)

Author

Rosati, Anna, primary, Ilvento, Lucrezia, additional, L'Erario, Manuela, additional, De Masi, Salvatore, additional, Biggeri, Annibale, additional, Fabbro, Giancarlo, additional, Bianchi, Roberto, additional, Stoppa, Francesca, additional, Fusco, Lucia, additional, Pulitanò, Silvia, additional, Battaglia, Domenica, additional, Pettenazzo, Andrea, additional, Sartori, Stefano, additional, Biban, Paolo, additional, Fontana, Elena, additional, Cesaroni, Elisabetta, additional, Mora, Donatella, additional, Costa, Paola, additional, Meleleo, Rosanna, additional, Vittorini, Roberta, additional, Conio, Alessandra, additional, Wolfler, Andrea, additional, Mastrangelo, Massimo, additional, Mondardini, Maria Cristina, additional, Franzoni, Emilio, additional, McGreevy, Kathleen S, additional, Di Simone, Lorena, additional, Pugi, Alessandra, additional, Mirabile, Lorenzo, additional, Vigevano, Federico, additional, and Guerrini, Renzo, additional

Published
2016
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46. Studi sull'evoluzione stratigrafica e tettonica di aree selezionate dell'offshore tirrenico

Author

Agate Mauro (1), Aiello Gemma (2), Budillon Francesca (2), Catalano Raimondo (1), D'Argenio Bruno (2, de Alteriis Giovanni (2), De Lauro Massimo (2), Ferraro Luciana (2), Infuso Salvina (1), Lucido Michele (1), Marsella Ennio (2), Mirabile Lorenzo (4), Sacchi Marco (2), Siniscalchi Agata (2), and Sulli Attilio (1)

Subjects
stratigrafia, margine continentale tirrenico, tettonica
Abstract

Vengono illustrati in questa nota i risultati preliminari di due crociere oceanografiche condotte nell'offshore tirrenico dall'Istituto di Ricerca Geomare Sud del CNR di Napoli a bordo della N/O Urania rispettivamente nell'ottobre 1992 e nel maggio 1993. Le ricerche effettuate sono inserite in un progetto di ricerca che il Geomare sta conducendo da alcuni anni sul tema "Stratigrafia e strutture dell'offshore tirrenico", articolato in vari sottoprogetti che prevedono lo studio di aree selezionate dei mari circostanti l'Italia meridionale tramite sismica monocanale di alta risoluzione.

Published
1995

50. Ground zero: not asthma at all.

Author

Benedictis, Fernando Maria, Benedictis, Diletta, Mirabile, Lorenzo, Pozzi, Marco, Guerrieri, Arcangela, and Di Pillo, Sabrina

Subjects
ASTHMA in children, ASTHMA treatment, TRACHEOMALACIA, DISEASE relapse, SPIROMETRY, THORACIC aorta, DIAGNOSIS
Abstract

Upper airway obstruction is commonly misdiagnosed as asthma. We report on four children with recurrent respiratory symptoms who had been erroneously diagnosed as having asthma and who received anti-asthma medication for several years. The evaluation of spirometry tracing was neglected in all cases. Subglottic stenosis, tracheomalacia secondary to tracheo-esophageal fistula, double aortic arch, and vocal cord dysfunction were suspected by direct inspection of the flow-volume curves and eventually diagnosed. The value of clinical history and careful evaluation of spirometry tracing in children with persistent respiratory symptoms is critically discussed. [ABSTRACT FROM AUTHOR]

Published
2015
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