268 results on '"Miracapillo, A"'
Search Results
2. Deep Learning Techniques for the Dermoscopic Differential Diagnosis of Benign/Malignant Melanocytic Skin Lesions: From the Past to the Present
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Linda Tognetti, Chiara Miracapillo, Simone Leonardelli, Alessio Luschi, Ernesto Iadanza, Gabriele Cevenini, Pietro Rubegni, and Alessandra Cartocci
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melanocytic skin lesions ,melanoma ,nevi ,atypical nevi ,artificial intelligence ,deep learning ,Technology ,Biology (General) ,QH301-705.5 - Abstract
There has been growing scientific interest in the research field of deep learning techniques applied to skin cancer diagnosis in the last decade. Though encouraging data have been globally reported, several discrepancies have been observed in terms of study methodology, result presentations and validation in clinical settings. The present review aimed to screen the scientific literature on the application of DL techniques to dermoscopic melanoma/nevi differential diagnosis and extrapolate those original studies adequately by reporting on a DL model, comparing them among clinicians and/or another DL architecture. The second aim was to examine those studies together according to a standard set of statistical measures, and the third was to provide dermatologists with a comprehensive explanation and definition of the most used artificial intelligence (AI) terms to better/further understand the scientific literature on this topic and, in parallel, to be updated on the newest applications in the medical dermatologic field, along with a historical perspective. After screening nearly 2000 records, a subset of 54 was selected. Comparing the 20 studies reporting on convolutional neural network (CNN)/deep convolutional neural network (DCNN) models, we have a scenario of highly performant DL algorithms, especially in terms of low false positive results, with average values of accuracy (83.99%), sensitivity (77.74%), and specificity (80.61%). Looking at the comparison with diagnoses by clinicians (13 studies), the main difference relies on the specificity values, with a +15.63% increase for the CNN/DCNN models (average specificity of 84.87%) compared to humans (average specificity of 64.24%) with a 14,85% gap in average accuracy; the sensitivity values were comparable (79.77% for DL and 79.78% for humans). To obtain higher diagnostic accuracy and feasibility in clinical practice, rather than in experimental retrospective settings, future DL models should be based on a large dataset integrating dermoscopic images with relevant clinical and anamnestic data that is prospectively tested and adequately compared with physicians.
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- 2024
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3. Switching to a 100% remote follow‐up of implantable cardiac electronic devices: Organizational model and results of a single center experience.
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Miracapillo, Gennaro, Addonisio, Luigi, De Sensi, Francesco, Orselli, Paolo, Piccinetti, Elena, Aramini, Carla, and Limbruno, Ugo
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SUCCESS , *MORTALITY , *T-test (Statistics) , *SCIENTIFIC observation , *COST analysis , *MAJOR adverse cardiovascular events , *DESCRIPTIVE statistics , *CHI-squared test , *TELEMEDICINE , *ORGANIZATIONAL structure , *MEDICAL consultation , *IMPLANTABLE cardioverter-defibrillators , *CARDIAC pacemakers , *DATA analysis software , *REACTION time , *PATIENT aftercare , *ALGORITHMS - Abstract
Introduction: During the SARS‐CoV‐2 COVID‐19 pandemic, the global health system needed to review important processes involved in daily routines such as outpatient activities within the hospital, including follow‐up visits of implantable cardiac electronic devices (CIEDs) carried out in office. The aim of this study is to describe our 3.5 years of real‐world experience of a full remote CIED follow‐up, evaluate the success rate of remote transmissions, and verify the adopted organizational model. Methods: From April 2020 to November 2023, all patients with an activated and well‐functioning remote monitoring (RM) system and automatic algorithms, like autocapture and autosensing, underwent exclusive RM follow‐up. Unscheduled in‐office visits were only prompted by remote yellow or red alerts. Patients were divided into two groups, based on available technology: Manual Transmission System (MTS) and Automatic Transmission System (ATS). The ATS group, in addition to ensuring a daily transmission of any yellow or red alerts, was checked at least every 15 days to ensure a valid connection. An automatic transmission was scheduled once a year, irrespective of alerts occurred. The MTS group provided a manual transmission every 6 months. Results: One thousand nine hundred thirty‐seven consecutive patients were included in the study. By the end of November 2023, a total of 1409 patients (1192 in the ATS and 217 in the MTS group) were still actively followed by our remote clinic (384 expired, 137 dismissed, 7 transferred). The overall success rate of transmissions with the adopted organizational model was 96.6% in the ATS group (connection index) and 87% in the MTS group. Conventional in‐hospital follow‐up visits decreased by 44%. Total clinic working time, resulting from the sum of the time spent during in‐hospital and remote follow‐up, after an initial increase, was progressively reduced to the actual −25%. Mortality rate for any cause was 7.5% per year in remote follow‐up patients and 8.3% (p=NS) in in‐office patients. In the ATS group, no device malfunctions were notified to our remote clinic, before we had already realized it through appropriate alerts. Conclusions: The available technology makes moving to a 100% remote clinic possible, without overwhelming clinic workflow, safely. Adopting an appropriate organizational model, it is possible to maintain high transmission success rates. The automatic transmissions allow a more frequent control of patients with CIED. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Deep Learning Techniques for the Dermoscopic Differential Diagnosis of Benign/Malignant Melanocytic Skin Lesions: From the Past to the Present.
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Tognetti, Linda, Miracapillo, Chiara, Leonardelli, Simone, Luschi, Alessio, Iadanza, Ernesto, Cevenini, Gabriele, Rubegni, Pietro, and Cartocci, Alessandra
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CONVOLUTIONAL neural networks , *SCIENTIFIC literature , *DERMOSCOPY , *DIFFERENTIAL diagnosis , *DEEP learning , *ARTIFICIAL intelligence - Abstract
There has been growing scientific interest in the research field of deep learning techniques applied to skin cancer diagnosis in the last decade. Though encouraging data have been globally reported, several discrepancies have been observed in terms of study methodology, result presentations and validation in clinical settings. The present review aimed to screen the scientific literature on the application of DL techniques to dermoscopic melanoma/nevi differential diagnosis and extrapolate those original studies adequately by reporting on a DL model, comparing them among clinicians and/or another DL architecture. The second aim was to examine those studies together according to a standard set of statistical measures, and the third was to provide dermatologists with a comprehensive explanation and definition of the most used artificial intelligence (AI) terms to better/further understand the scientific literature on this topic and, in parallel, to be updated on the newest applications in the medical dermatologic field, along with a historical perspective. After screening nearly 2000 records, a subset of 54 was selected. Comparing the 20 studies reporting on convolutional neural network (CNN)/deep convolutional neural network (DCNN) models, we have a scenario of highly performant DL algorithms, especially in terms of low false positive results, with average values of accuracy (83.99%), sensitivity (77.74%), and specificity (80.61%). Looking at the comparison with diagnoses by clinicians (13 studies), the main difference relies on the specificity values, with a +15.63% increase for the CNN/DCNN models (average specificity of 84.87%) compared to humans (average specificity of 64.24%) with a 14,85% gap in average accuracy; the sensitivity values were comparable (79.77% for DL and 79.78% for humans). To obtain higher diagnostic accuracy and feasibility in clinical practice, rather than in experimental retrospective settings, future DL models should be based on a large dataset integrating dermoscopic images with relevant clinical and anamnestic data that is prospectively tested and adequately compared with physicians. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
5. Cardiac resynchronization therapy defibrillators in patients with permanent atrial fibrillation
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Antonio Rapacciuolo, Saverio Iacopino, Antonio D'Onofrio, Antonio Curnis, Ennio C. Pisanò, Mauro Biffi, Paolo Della Bella, Antonio Dello Russo, Fabrizio Caravati, Gabriele Zanotto, Valeria Calvi, Giovanni Rovaris, Gaetano Senatore, Daniele Nicolis, Matteo Santamaria, Massimo Giammaria, Giampiero Maglia, Antonio Duca, Giuseppe Ammirati, Salvo Andrea Romano, Marcello Piacenti, Eduardo Celentano, Giovanni Bisignani, Paola Vaccaro, Gennaro Miracapillo, Matteo Bertini, Gerardo Nigro, Daniele Giacopelli, Alessio Gargaro, and Caterina Bisceglia
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Atrial fibrillation ,Cardiac resynchronization therapy ,Heart failure ,Heart rate ,Defibrillation shock ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims There are conflicting data on the benefit of cardiac resynchronization therapy (CRT) in heart failure (HF) patients with permanent atrial fibrillation (AF). We aimed to compare patient outcomes according to the presence or absence of permanent AF at device implantation. Methods and results We retrospectively analysed remote monitoring data from 1141 CRT defibrillators. Propensity score with inverse‐probability weighting method was used to balance AF and sinus rhythm (SR) groups. Analysis endpoints included total mortality, appropriate defibrillation shocks, and CRT percentage. There were 229 patients (20.1%) in the AF group and 912 patients (79.9%) in the SR group. Compared with SR patients, AF patients were older (median age, 77 vs. 72 years, P
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- 2021
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6. Body mass index is related to unsuccessful puncture attempts and failure to axillary vein cannulation during ultrasound-guided cardiac electronic device implantation
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De Sensi, Francesco, Addonisio, Luigi, Baratta, Pasquale, Breschi, Marco, Cresti, Alberto, Miracapillo, Gennaro, and Limbruno, Ugo
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- 2021
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7. Mortality after cardioverter-defibrillator replacement: Results of the DECODE survival score index
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Zoni-Berisso, Massimo, Martignani, Cristian, Ammendola, Ernesto, Narducci, Maria Lucia, Caruso, Davide, Miracapillo, Gennaro, Notarstefano, Pasquale, Carinci, Valeria, Pierantozzi, Attilio, Ciaramitaro, Gianfranco, Calò, Leonardo, Zennaro, Mauro, Infusino, Tommaso, Ferretti, Carlo, Sassone, Biagio, Licciardello, Giovanni, Setti, Sergio, Terzaghi, Carlotta, Malacrida, Maurizio, and Biffi, Mauro
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- 2021
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8. An international multicentre experience with the third-generation laser balloon system: safety, efficiency, and efficacy
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Martignani, C, primary, Bartoli, L, additional, Spadotto, A, additional, Tilz, R R, additional, Heeger, C H, additional, Giaccardi, M, additional, Miracapillo, G, additional, Forleo, G B, additional, Schiavone, M, additional, Giomi, A, additional, Arena, G, additional, Ciconte, G, additional, Pappone, C, additional, Montemerlo, E, additional, and Rovaris, G, additional
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- 2023
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9. Valutazione del riscontro di componenti monoclonali in pazienti ospedalizzati durante la pandemia da SARS-CoV-2
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SASSO, Mauro, primary, RUTA, Rosalba, additional, MIRACAPILLO, Vincenza, additional, and CECI, Luigi, additional
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- 2023
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10. A risk‐scoring model for the differential diagnosis of lentigo maligna and other atypical pigmented facial lesions of the face: the facial iDScore
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Tognetti, Linda, primary, Cartocci, Alessandra, additional, Żychowska, Magdalena, additional, Savarese, Imma, additional, Cinotti, Elisa, additional, Pizzichetta, Maria Antonietta, additional, Moscarella, Elvira, additional, Longo, Caterina, additional, Farnetani, Francesca, additional, Guida, Stefania, additional, Paoli, John, additional, Lallas, Aimilios, additional, Tiodorovic, Danica, additional, Stanganelli, Ignazio, additional, Magi, Serena, additional, Dika, Emi, additional, Zalaudek, Iris, additional, Suppa, Mariano, additional, Argenziano, Giuseppe, additional, Pellacani, Giovanni, additional, Perrot, Jean Luc, additional, Miracapillo, Chiara, additional, Rubegni, Giovanni, additional, Cevenini, Gabriele, additional, and Rubegni, Pietro, additional
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- 2023
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11. Achilles’ heel of integrated hydrologic models: The stream-aquifer flow exchange, and proposed alternative
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Morel-Seytoux, Hubert J., Miller, Calvin D., Mehl, Steffen, and Miracapillo, Cinzia
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- 2018
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12. Follow-up of implantable cardiac electronic devices during the Covid-19 pandemic: organizational model and results of a single center experience
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Miracapillo, G, primary, Addonisio, L, additional, De Sensi, F, additional, Orselli, P, additional, Piccinetti, E, additional, Aramini, C, additional, Del Maestro, M, additional, and Limbruno, U, additional
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- 2023
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13. Follow-up of implantable cardiac electronic devices during the Covid-19 pandemic: organizational model and results of a single center experience
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G Miracapillo, L Addonisio, F De Sensi, P Orselli, E Piccinetti, C Aramini, M Del Maestro, and U Limbruno
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Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Funding Acknowledgements Type of funding sources: None. Introduction During the SARS-CoV-2 COVID-19 pandemic, the global health system has had to review important processes involved in daily routines such as outpatient activities within the hospital, including follow-up visits of implantable cardiac electronic devices (CIEDs), pacemakers (PMs) and implantable defibrillators (ICDs) carried out in office. The aim of this study was to prospectively evaluate the success rate of remote transmissions of all devices followed by the CIED control clinic and verify the adopted organizational models. Methods All patients with remote monitoring system were considered in the study if automatic algorithm such as autocapture and autosensing were activated and well-functioning. Between January 2021 and November 2022, they were completely followed by remote monitoring and called for unscheduled in-office visit only because of remote yellow or red alarms. Patients were divided into two groups: Manual Transmission System (MTS) and Automatic Transmission System (ATS), based on the available technology. Organizational models shown in figures 1-2, were followed for the two groups. The technology of the ATS group, in addition to ensuring a daily transmission of any yellow or red alarms, allowed a control of missed communication at least every 14 days. The MTS group provided a manual transmission every 6 months. The ATS group was controlled at least once in the year, even if no alarms occurred. Results At the end of 2022 a total of 1193 patients were followed remotely by our center. Of these, 238 from the MTS group and 955 from the ATS group. 3314 remote transmission required medical intervention, which generated 182 unscheduled outpatient visits, mainly due to lack of transmission for prolonged periods, failure of the autocapture test and newly onset atrial fibrillation. 3496 transmissions were generated and 120 transmissions were missed; the overall success rate of transmissions with the organizational model adopted was 96.6% (connectivity index). On average, the monthly rate of unconnected manual devices was 5.1% while 3.5% for automatic devices. 2-year mortality was 12.7%. Conclusions By adopting an appropriate organizational model, it is possible to maintain high transmission success rates. The available technology allows you to change hospital outpatient habits in the cardiology field for CIED checks and move to a virtual clinic safely. The automatic transmission technology allows a more frequent control of patients with CIED, the impact on the patients' health must be assessed.
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- 2023
14. Temporal association between drops in thoracic impedance and malignant ventricular arrhythmia: A longitudinal analysis of remote monitoring trends
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Rodio, Giovanna, primary, Iacopino, Saverio, additional, Pisanò, Ennio C, additional, Calvi, Valeria, additional, Rovaris, Giovanni, additional, Marini, Massimiliano, additional, Giammaria, Massimo, additional, Caravati, Fabrizio, additional, Maglia, Giampiero, additional, Zanotto, Gabriele, additional, Della Bella, Paolo, additional, Biffi, Mauro, additional, Curnis, Antonio, additional, Maines, Massimiliano, additional, Orsida, Daniela, additional, Santamaria, Matteo, additional, Bisignani, Giovanni, additional, Baroni, Matteo, additional, Lissoni, Fabio, additional, Duca, Antonio, additional, Forleo, Giovanni B, additional, Piemontese, Carlo, additional, De Salvia, Alberto, additional, Miracapillo, Gennaro, additional, Celentano, Eduardo, additional, Zecchin, Massimo, additional, Luzzi, Giovanni, additional, Giacopelli, Daniele, additional, Gargaro, Alessio, additional, and D'Onofrio, Antonio, additional
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- 2023
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15. Image integration guided ablation of left outflow tract ventricular tachycardia: Is coronary angiography still necessary?
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Francesco De Sensi, Gennaro Miracapillo, Alberto Cresti, Francesco Paneni, and Ugo Limbruno
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Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2018
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16. Impact of aquifer desaturation on steady-state river seepage
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Morel-Seytoux, Hubert J., Miracapillo, Cinzia, and Mehl, Steffen
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- 2016
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17. Temporal association between drops in thoracic impedance and malignant ventricular arrhythmia: A longitudinal analysis of remote monitoring trends
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Giovanna Rodio, Saverio Iacopino, Ennio C. Pisanò, Valeria Calvi, Giovanni Rovaris, Massimiliano Marini, Massimo Giammaria, Fabrizio Caravati, Giampiero Maglia, Gabriele Zanotto, Paolo Della Bella, Mauro Biffi, Antonio Curnis, Massimiliano Maines, Daniela Orsida, Matteo Santamaria, Giovanni Bisignani, Matteo Baroni, Fabio Lissoni, Antonio Duca, Giovanni B. Forleo, Carlo Piemontese, Alberto De Salvia, Gennaro Miracapillo, Eduardo Celentano, Massimo Zecchin, Giovanni Luzzi, Daniele Giacopelli, Alessio Gargaro, and Antonio D'Onofrio
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implantable cardioverter defibrillator ,cardiac resynchronization therapy ,heart failure ,thoracic impedance ,ventricular arrhythmias ,Physiology (medical) ,Cardiology and Cardiovascular Medicine - Published
- 2023
18. Temporal association between drops in throracic impedance and malignant ventricular arrhythmia:A longitudinal analysis of remote monitoring trends
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Rodio, G., Iacopino, S., Pisanò, E., Calvi, V., Rovasis, G., Marini, M., Giammaria, M., Caravati, F., Maglia, G., Zanotto, G., Dellabella, P., Biffi, M., Curnis, A., Maines, M., Orsida, D., Santamaria, M., Bisignani, G., Forleo, G. B., Piemontese, C., Desalvia, A., Miracapillo, G., Celentano, E., Zecchin, M., Luzzi, G., Giacopelli, D., Gargaro, A., and D'Onofrio, A.
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- 2023
19. Epicardial thoracoscopic robotic-assisted catheter navigation in a pig
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De Sensi, Francesco, Berruezo, Antonio, Miracapillo, Gennaro, Formisano, Giampaolo, Bianchi, Paolo Pietro, and Limbruno, Ugo
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- 2019
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20. Numerical Simulation of Radionuclides Migration in the Far Field of a Geological Repository
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Miracapillo, Cinzia and Ferroni, Luisa
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- 2015
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21. Sustained Ventricular Tachycardia In An Apparently Healthy Heart: A Very Localized Left Dominant Arrhythmogenic Cardiomyopathy
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Alberto Cresti, MD, Francesco De Sensi, MD, Silva Severi, MD, and Gennaro Miracapillo, MD
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Arrhythmogenic Cardiomyopathy ,Ventricular Tachycardia ,Cardiac Magnetic Resonance ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
A 62-year-old man admitted for presyncope presented two symptomatic sustained ventricular tachycardia with right bundle branch morphology and inferior axis suggesting a pathology of the left ventricular lateral wall, the site where Cardiac Magnetic Resonance demonstrated a thinned, hypokinetic segment with fibro-fatty subepicardial infiltration. A very localized Left Dominant Arrhythmogenic Cardiomyopathy was diagnosed and an ICD implanted.
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- 2014
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22. Radionuclides Migration in the Far Field of Geological Repositories: A Numerical Example
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Ferroni, Luisa and Miracapillo, Cinzia
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- 2014
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23. Stepwise approach for visualization and reconstruction of pulmonary valve with intracardiac echocardiography
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Alberto Cresti, Gennaro Miracapillo, Marco Breschi, Francesco De Sensi, Ugo Limbruno, and Luigi Addonisio
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Aortic valve ,medicine.medical_specialty ,Radiofrequency ablation ,030204 cardiovascular system & hematology ,Ventricular tachycardia ,Intracardiac injection ,law.invention ,03 medical and health sciences ,Imaging, Three-Dimensional ,0302 clinical medicine ,law ,Internal medicine ,medicine.artery ,medicine ,Humans ,Ventricular outflow tract ,cardiovascular diseases ,030212 general & internal medicine ,Cardiac Surgical Procedures ,Pulmonary Valve ,business.industry ,General Medicine ,medicine.disease ,Coronary arteries ,medicine.anatomical_structure ,Surgery, Computer-Assisted ,Echocardiography ,Pulmonary valve ,Pulmonary artery ,cardiovascular system ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Ventricular tachycardia and premature ventricular complexes (PVCs) arising from right ventricular outflow tract (RVOT) are the most common type of ventricular arrhythmias (VAs) in patients without structural heart disease. Radiofrequency ablation is now the gold standard of treatment in this setting due to high efficacy rates and optimal safety profile. During the last few years, the pulmonary valve (PV) and the pulmonary artery (PA) have attracted much attention as reliable sites of origin of RVOT-type arrhythmias. In the mean while intracardiac echocardiogram (ICE) has undoubtedly improved our understanding of the cardiac anatomy. Aim of this paper is to provide an illustrated step-by-step guide on how to use ICE with the CARTOSOUND module to visualize and reconstruct 3D shell of the RV, the PV, as well of other contiguous anatomical structures (i.e., the aortic valve and coronary arteries) to perform aware and safe ablation in this region. This article is protected by copyright. All rights reserved.
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- 2021
24. A call for safety during electrophysiological procedures: US in, why not US out?
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De Sensi, Francesco, Miracapillo, Gennaro, Addonisio, Luigi, Breschi, Marco, and Paneni, Francesco
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- 2017
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25. Thromboembolic Events Following Atrial Fibrillation Cardioversion and Ablation: What’s the Culprit?
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Francesco De Sensi, Gennaro Miracapillo, Luigi Addonisio, Marco Breschi, Alberto Cresti, Pasquale Baratta, Francesco Paneni, and Ugo Limbruno
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atrial fibrillation ablation ,stroke ,iatrogenic interatrial septum defect ,paradoxical embolism ,anticoagulant interruption ,Medicine (General) ,R5-920 - Abstract
Stroke is a rare but possible complication after atrial fibrillation (AF) ablation. However, its etiopathogenesis is far from being completely characterized. Here we report a case of stroke, with recurrent peripheral embolism after AF ablation procedure. In our patient, an in situ femoral vein thrombosis and iatrogenic atrial septal defect were simultaneously detected. A comprehensive review of multiple pathophysiological mechanisms of stroke in this context is provided. The case underlines the importance of a global evaluation of patients undergoing AF ablation.
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- 2019
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26. Five waves of COVID-19 pandemic in Italy: results of a national survey evaluating the impact on activities related to arrhythmias, pacing, and electrophysiology promoted by AIAC (Italian Association of Arrhythmology and Cardiac Pacing)
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Boriani, G., Guerra, F., De Ponti, R., D'Onofrio, A., Accogli, M., Bertini, M., Bisignani, G., Forleo, G. B., Landolina, M., Lavalle, C., Notarstefano, P., Ricci, R. P., Zanotto, G., Palmisano, P., Luise, R., De Bonis, S., Pangallo, A., Talarico, A., Maglia, G., Aspromonte, V., Nigro, G., Bianchi, V., Rapacciuolo, A., Ammendola, E., Solimene, F., Stabile, G., Biffi, M., Ziacchi, M., Malpighi, P. S. O., Saporito, D., Casali, E., Turco, V., Malavasi, V. L., Vitolo, M., Imberti, J. F., Anna, A. S., Zardini, M., Placci, A., Quartieri, F., Bottoni, N., Carinci, V., Barbato, G., De Maria, E., Borghi, A., Ramazzini, O. B., Bronzetti, G., Tomasi, C., Boggian, G., Virzi, S., Sassone, B., Corzani, A., Sabbatani, P., Pastori, P., Ciccaglioni, A., Adamo, F., Scaccia, A., Spampinato, A., Patruno, N., Biscione, F., Cinti, C., Pignalberi, C., Calo, L., Tancredi, M., Di Belardino, N., Ricciardi, D., Cauti, F., Rossi, P., Cardinale, M., Ansalone, G., Narducci, M. L., Pelargonio, G., Silvetti, M., Drago, F., Santini, L., Pentimalli, F., Pepi, P., Caravati, F., Taravelli, E., Belotti, G., Rordorf, R., Mazzone, P., Bella, P. D., Rossi, S., Canevese, L. F., Cilloni, S., Doni, L. A., Vergara, P., Baroni, M., Perna, E., Gardini, A., Negro, R., Perego, G. B., Curnis, A., Arabia, G., Russo, A. D., Marchese, P., Dell'Era, G., Occhetta, E., Pizzetti, F., Amellone, C., Giammaria, M., Devecchi, C., Coppolino, A., Tommasi, S., Anselmino, M., Coluccia, G., Guido, A., Rillo, M., Palama, Z., Luzzi, G., Pellegrino, P. L., Grimaldi, M., Grandinetti, G., Vilei, E., Potenza, D., Scicchitano, P., Favale, S., Santobuono, V. E., Sai, R., Melissano, D., Candida, T. R., Bonfantino, V. M., Di Canda, D., Gianfrancesco, D., Carretta, D., Pisano, E. C. L., Medico, A., Giaccari, R., Aste, R., Murgia, C., Nissardi, V., Sanna, G. D., Firetto, G., Crea, P., Ciotta, E., Sgarito, G., Caramanno, G., Ciaramitaro, G., Faraci, A., Fasheri, A., Di Gregorio, L., Campsi, G., Muscio, G., Giannola, G., Padeletti, M., Del Rosso, A., Nesti, M., Miracapillo, G., Giovannini, T., Pieragnoli, P., Rauhe, W., Marini, M., Guarracini, F., Ridarelli, M., Fedeli, F., Mazza, A., Zingarini, G., Andreoli, C., Carreras, G., Zorzi, A., Rossillo, A., Ignatuk, B., Zerbo, F., Molon, G., Fantinel, M., Zanon, F., Marcantoni, L., Zadro, M., and Bevilacqua, M.
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Cardiac resynchronization therapy ,Remote monitoring ,Emergency Medicine ,Internal Medicine ,Ablation ,Arrhythmia ,Atrial fibrillation ,COVID-19 ,Implantable cardioverter defibrillators ,Pacemakers - Abstract
The subsequent waves of the COVID-19 pandemic in Italy had a major impact on cardiac care.A survey to evaluate the dynamic changes in arrhythmia care during the first five waves of COVID-19 in Italy (first: March-May 2020; second: October 2020-January 2021; third: February-May 2021; fourth: June-October 2021; fifth: November 2021-February 2022) was launched.A total of 127 physicians from arrhythmia centers (34% of Italian centers) took part in the survey. As compared to 2019, a reduction in 40% of elective pacemaker (PM), defibrillators (ICD), and cardiac resynchronization devices (CRT) implantations, with a 70% reduction for ablations, was reported during the first wave, with a progressive and gradual return to pre-pandemic volumes, generally during the third-fourth waves, slower for ablations. For emergency procedures (PM, ICD, CRT, and ablations), recovery from the initial 10% decline occurred in most cases during the second wave, with some variability. However, acute care for atrial fibrillation, electrical cardioversions, and evaluations for syncope showed a prolonged reduction of activity. The number of patients with devices which started remote monitoring increased by 40% during the first wave, but then the adoption of remote monitoring declined.The dramatic and profound derangement in arrhythmia management that characterized the first wave of the COVID-19 pandemic was followed by a progressive return to the volume of activities of the pre-pandemic periods, even if with different temporal dynamics and some heterogeneity. Remote monitoring was largely implemented during the first wave, but full implementation is needed.
- Published
- 2022
27. Body mass index is related to unsuccessful puncture attempts and failure to axillary vein cannulation during ultrasound-guided cardiac electronic device implantation
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Ugo Limbruno, Pasquale Baratta, Alberto Cresti, Francesco De Sensi, Luigi Addonisio, Marco Breschi, and Gennaro Miracapillo
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Male ,Catheterization, Central Venous ,medicine.medical_specialty ,Context (language use) ,Punctures ,030204 cardiovascular system & hematology ,Body Mass Index ,03 medical and health sciences ,0302 clinical medicine ,Physiology (medical) ,medicine ,Humans ,030212 general & internal medicine ,Axillary Vein ,Vein ,Ultrasonography, Interventional ,Cephalic vein ,Univariate analysis ,Receiver operating characteristic ,business.industry ,Infant, Newborn ,Odds ratio ,Perioperative ,Defibrillators, Implantable ,Surgery ,medicine.anatomical_structure ,Electronics ,Cardiology and Cardiovascular Medicine ,Axillary vein ,business - Abstract
Ultrasound (US)-guided axillary vein cannulation is effective and safe during cardiac implantable electronic devices (CIEDs). It is a reasonable alternative to other techniques in order to shorten procedural time and decrease perioperative complications. However, in this context, the short-axis (out-of-plane) visualization to guide the vein puncture is the most used technique. The aim of our study is to describe a single-center experience with the US long-axis (in-plane) technique defining predictors of unsuccessful puncture attempts and failure to axillary vein cannulation in a cohort of patients undergoing CIEDs procedures. From November 2017 to June 2019, consecutive patients undergoing CIEDs procedures were enrolled in the study. US-guided long axis (in-plane) view to guide axillary vein cannulation was used in all subjects. Unsuccessful puncture attempts (UAs) and complete failures to cannulate the vein were collected for each procedure. All patients were evaluated on a daily basis until hospital discharge and at 1-month follow up visit. Among 119 subjects (M: F = 75:44), mean age was 79 ± 9 years, mean BMI 25.7 ± 4.3 kg/m2, and mean BSA 1.74 ± 0.4 m2. We placed 95 pacemakers (32 single-, 61 dual-, and 2 triple-chamber) and 20 ICDs (7 single, 6 dual, 7 triple chambers). An upgrade from dual-chamber to triple-chamber device was carried out with the addition of a new lead in 3 patients. During a system revision, one new electrode was implanted. The overall leads inserted were 204. There were 33 initial unsuccessful attempts in 22/119 patients. US-guided axillary access was finally successful in 94.9% of patients (113/119). In the other cases (6/119), cephalic vein was isolated or blinded subclavian puncture was performed. Interestingly, at univariate analysis, an increasing BMI and BSA, male sex, and anticoagulant therapy were predictors of unsuccessful attempts or failure to cannulate the vein with US. Among those subjects, the multivariate logistic regression showed significant correlations only between BMI and unsuccessful attempts: odds ratio (OR) = 1.16, p = 0.009 [95% CI = 1.04–1.31], and BMI with failure to cannulate the vein: OR = 1.21, p = 0.03 [95%CI = 1.01–1.45]. The receiver operating characteristic (ROC) curves individuated the best BMI value cutoff point at 27 kg/m2 (area under the curve [AUC]: 68.6%) having a sensitivity of 63.6% and a specificity of 66.5% for unsuccessful puncture attempts; a BMI value of 28 kg/m2 (AUC 74.9%) had a sensitivity of 66.7% and a specificity of 66.7% for failure to cannulate the vein with the US-guided approach. Axillary vein long-axis (in-plane) US-guided cannulation during CIEDs implantation is characterized by a high success rate (94.9%). An elevated BMI is significantly related to unsuccessful puncture attempts or failure to cannulation. The higher is the BMI, the more are the chances to have difficult vein puncture or cannulation failure and to switch from US-guided approach to another technique.
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- 2020
28. Third-generation laser balloon ablation for atrial fibrillation treatment: a multicenter experience
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Giovanni Rovaris, Giovanni B. Forleo, Marzia Giaccardi, D Grassini, E Montemerlo, Gennaro Miracapillo, A Giomi, M. Pozzi, Mauro Biffi, Marco Schiavone, C. Martignani, Daniele Giacopelli, Matteo Ziacchi, and Andrea Colella
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Atrial fibrillation ,Balloon ,medicine.disease ,Ablation ,Laser ,Third generation ,law.invention ,law ,Internal medicine ,medicine ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Laser balloon ablation is a promising option for performing pulmonary vein isolation (PVI) which is the cornerstone of invasive atrial fibrillation (AF) treatment. Purpose We aimed to investigate the acute efficacy and safety of the novel third-generation of the laser balloon system in an initial multicenter experience. Methods First and consecutive patients who underwent PVI with LB3 for drug-resistant paroxysmal or persistent AF at 7 Italian sites were included in this analysis. Study endpoints were acute procedural efficacy, defined as successful isolation of all identified PVs without radiofrequency touch-up, total and fluoroscopy times, and periprocedural complications. Results Our population included 86 patients (81% males, mean age 60.6±9.5 years) who underwent a procedure of PVI using LB3 between June 2020 and March 2021. Most patients had paroxysmal AF (74%) and were in sinus rhythm at the beginning of the procedure. The mean procedure time was 138±60 min; fluoroscopy time was 22±17 min and the mean ablation time was 44±40 min. Of the 313 targeted PVs, 311 (99.4%) could be isolated with first-pass LB3 application, while 2 (0.6%) required radiofrequency touchup. At the end of the procedure, all patients were in sinus rhythm and 26 (32%) received electrical cardioversion to achieve stable sinus rhythm. The total rate of major compilations was 1.2% (1/82 patients): one pericardial tamponade requiring epicardial puncture. No surgical intervention was necessary, and the patient recovered without any sequalae. There were no vascular access complications or phrenic nervy palsy. Three pinhole balloon raptures (3.5%) were observed during energy applications that required replacement of the whole system but had no effect on patient safety. Conclusions In a first multicenter experience, the LB3 system for PVI was safe with excellent acute efficacy. Funding Acknowledgement Type of funding sources: None.
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- 2021
29. The L-band Land Mobile (LLM) payload: key technologies and test results
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D’Elia, R., Giubilei, R., Grelli, G., Miracapillo, L., Sassorossi, T., Vatalaro, Francesco, editor, and Ananasso, Fulvio, editor
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- 1996
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30. Can Right Ventricular Pacing be Useful in the Assessment of Cavo-tricuspid Isthumus Block?
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Gennaro Miracapillo, Alessandro Costoli, Luigi Addonisio, Marco Breschi, and Silva Severi
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Atrial flutter ,Radiofrequency ablation ,Right ventricle pacing ,Coronary sinus pacing. ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: Cavo-tricuspid isthmus (CTI) block is currently assessed by coronary sinus (CS) pacing or low lateral and septal atrial pacing. Occasionally, CS catheterization through the femoral route can be difficult to perform or right atrial pacing can be problematic because of catheter instability or saturation of the atrial electrograms recorded near the catheter. Objectives: Our aim was to evaluate the feasibility of assessing cavo-tricuspid isthmus block by means of right ventricular (RV) pacing in patients with ventriculo-atrial conduction, comparing it with CS pacing.Methods: Circumannular activation was analyzed during CS and RV pacing in consecutive patients in sinus rhythm undergoing CTI ablation for typical atrial flutter. Patients without ventriculo-atrial conduction were excluded from the study. The linear lesion was created during RV pacing and split atrial signals on the ablation line were analyzed. CTI block was confirmed by analyzing local electrograms on the line of block and circumannular activation during CS and RV pacing. Results: Out of 31 patients, 20 displayed ventriculo-atrial conduction (64%) and were included in the study. Before ablation, during RV stimulation, the collision front of circumannular activation shifted counterclockwise in contrast with the pattern observed during CS pacing. After ablation, circumannular activation was similar during CS and RV pacing, showing fully descending lateral right atrium activation, even if double potentials registered on the ablation line were less widely split during RV pacing than CS pacing (111±26 ms vs 128±30 , p=0.0001).Conclusions: In patients with ventriculo-atrial conduction, tricuspid annulus activation during CS and RV pacing is similar, before and after CTI ablation. The occurrence of split atrial electrograms separated by an isoelectric interval registered on the line of block can be detected during CS or RV pacing. In patients with difficult CS catheterization via the femoral vein, before trying the subclavian or internal jugular route, if retrograde ventriculo-atrial conduction is present, RV pacing can be an easy trick to assess isthmus block.
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- 2008
31. Third-generation laser balloon ablation for atrial fibrillation treatment: a multicenter experience
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Rovaris, G, primary, Martignani, C, additional, Miracapillo, G, additional, Colella, A, additional, Giaccardi, M, additional, Forleo, G.B, additional, Giomi, A, additional, Giacopelli, D, additional, Grassini, D, additional, Pozzi, M, additional, Montemerlo, E, additional, Ziacchi, M, additional, Schiavone, M, additional, and Biffi, M, additional
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- 2021
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32. Prevalence of auricular thrombosis before atrial flutter cardioversion: a 17-year transoesophageal echocardiographic study
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Cresti, Alberto, García-Fernández, Miguel Angel, De Sensi, Francesco, Miracapillo, Gennaro, Picchi, Andrea, Scalese, Marco, and Severi, Silva
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- 2016
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33. Cardiac resynchronization therapy defibrillators in patients with permanent atrial fibrillation
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Rapacciuolo, Antonio, primary, Iacopino, Saverio, additional, D'Onofrio, Antonio, additional, Curnis, Antonio, additional, Pisanò, Ennio C., additional, Biffi, Mauro, additional, Della Bella, Paolo, additional, Dello Russo, Antonio, additional, Caravati, Fabrizio, additional, Zanotto, Gabriele, additional, Calvi, Valeria, additional, Rovaris, Giovanni, additional, Senatore, Gaetano, additional, Nicolis, Daniele, additional, Santamaria, Matteo, additional, Giammaria, Massimo, additional, Maglia, Giampiero, additional, Duca, Antonio, additional, Ammirati, Giuseppe, additional, Romano, Salvo Andrea, additional, Piacenti, Marcello, additional, Celentano, Eduardo, additional, Bisignani, Giovanni, additional, Vaccaro, Paola, additional, Miracapillo, Gennaro, additional, Bertini, Matteo, additional, Nigro, Gerardo, additional, Giacopelli, Daniele, additional, Gargaro, Alessio, additional, and Bisceglia, Caterina, additional
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- 2021
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34. Pocket Hematoma: A Call for Definition
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DE SENSI, FRANCESCO, MIRACAPILLO, GENNARO, CRESTI, ALBERTO, SEVERI, SILVA, and AIRAKSINEN, KARI EINO JUHANI
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- 2015
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35. Latent tuberculosis infection in patients with chronic plaque psoriasis: evidence from the Italian Psocare Registry*
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Gisondi, P., Cazzaniga, S., Chimenti, S., Maccarone, M., Picardo, M., Girolomoni, G., Naldi, L., Griseta, V., Miracapillo, A., Azzini, M., Mocci, L., Michelini, M., Offidani, A., Bernardini, L., Campanati, A., Ricotti, G., Giacchetti, A., Norat, M., Gualco, F., Castelli, A., Cuccia, A., Diana, A., Roncarolo, G., Belli, M. A., Baldassarre, M. A., Santoro, G., Vena, G. A., Lo Console, F., Filotico, R., Mastrandrea, V., Brunetti, B., Musumeci, F., Carrabba, E., Dal Mas, P., Annicchiarico, F., Benvegnù, B., Spaziani, G., Cusano, F., Iannazzone, Saletta S., Galluccio, A., Pezza, M., Marchesi, L., Imberti, G., Reseghetti, A., Barbera, C., Reggiani, M., Lanzoni, A., Patrizi, A., Bardazzi, F., Antonucci, A., De Tommaso, S., Balestri, R., Wallnofer, W., Ingannamorte, F., Calzavara-Pinton, P., Iannazzi, S., Zane, C., Capezzera, R., Bassisi, S., Rossi, M. T., Altamura, V., Vigl, W., Nobile, C., Aste, N., Murgia, S., Mugheddu, C., Scuderi, G., Baglieri, F., Di Dio, C., Grilli, Cilioni E., Mastronardi, C., Agnusdei, C. P., Antrilli, A., Aulisa, L., Raimondo, U., di Luzio, Scotto G., Battarra, V. C., Farro, P., Plaitano, R., Micali, G., Musumeci, M. L., Massimino, D., Li Calzi, M., La Greca, S., Pettinato, M., Sapienza, G., Valenti, G., De Giacomo, P. F., dʼAmico, D., Arcangeli, F., Brunelli, D., Ghetti, E., Tulli, A., Assi, G., Laria, G., Prestinari, F., Spadafora, S., Coppola, M., Caresana, G., Pezzarossa, E., Domaneschi, E., Felisi, C., Donato, L., Bertero, M., Musso, L., Pa lazzini, S., Bruscino, P., Agozzino, U. C., Ottaviani, M., Simoncini, C., Virgili, A., Osti, F., Fabbri, P., Volpi, W., Caproni, M., Lotti, T., Prignano, F., Buggiani, G., Troiano, M., Fenizi, G., Altobella, A., Amoruso, A., Condello, M., Goffredo, A., Righini, M. G., Alessandrini, F., Satolli, F., Zampetti, M., Bertani, E., Fossati, S., Parodi, A., Burlando, M., Fiorucci, C., Nigro, A., Ghigliotti, G., Massone, L., Moise, G. M., Serrai, M., Cannata, G., Campagnoli, A. M., Daly, M., Leporati, C., Peila, R., Filosa, G., Bugatti, L., Nicolini, M., Nazzari, G., Cestari, R., Anastasio, F., Larussa, F. M., Pollice, N., De Francesco, F., Mazzocchetti, G., Peris, K., Fargnoli, M. C., Di Cesare, A., De Angelis, L., Flati, G., Biamonte, A. S., Quarta, G., Congedo, M., Carcaterra, A., Strippoli, D., Fideli, D., Marsili, F., Celli, M., Ceccarini, M., Bachini, L., DʼOria, M., Schirripa, V., De Filippi, C., Martini, P., Lapucci, E., Mazzatenta, C., Ghilardi, A., Simonacci, M., Bettacchi, A., Gasco, R., Zanca, A., Battistini, S., Dattola, S., Vernaci, R., Postorino, F., Zampieri, P. F., Padovan, C., González Intchaurraga, M. A., Ladurner, J., Guarneri, B., Cannavò, S., Manfrè, C., Borgia, F., Guerra, Puglisi A., Sedona, P., Cattaneo, A., Carrera, C., Fracchiolla, C., Mozzanica, N., Prezzemolo, L., Menni, S., Lodi, A., Martino, P., Monti, M., Mancini, L., Sacrini, F., Altomare, G. F., Taglioni, M., Lovati, C., Mercuri, S. R., Schiesari, G., Giannetti, A., Conti, A., Lasagni, C., Greco, M., Ronsini, G., Schianchi, S., Fiorentini, C., Niglietta, S., Maglietta, R., Padalino, C., Crippa, D., Pini, M., Rossi, E., Tosi, D., Armas, M., Ruocco, V., Ayala, F., Balato, N., Gaudiello, F., Cimmino, G. F., Monfrecola, G., Gallo, L., Argenziano, G., Fulgione, E., Berruti, G., Mozzillo, R., Ceparano, S., De Michele, I., Giorgiano, D., Leigheb, G., Deledda, S., Peserico, A., Alaibac, M., Piaserico, S., Schiesari, L., Dan, G., Mattei, I., Oro, E., Aricò, M., Bongiorno, M. R., Angileri, R., Amato, S., Todaro, F., Milioto, M., Bellastro, R., Di Nuzzo, S., De Panfilis, G., Zanni, M., Borroni, G., Cananzi, R., Brazzelli, V., Lisi, P., Stingeni, L., Hansel, K., Pierfelice, V., Donelli, S., Rastelli, D., Gasperini, M., Barachini, P., Cecchi, R., Bartoli, L., Pavesi, M., De Paola, S., Corradin, M. T., Ricciuti, F., Piccirillo, A., Viola, L., Tataranni, M., Mautone, M. G., Lo Scocco, G., Niccoli, M. C., Brunasso Vernetti, A. M.G., Gaddoni, G., Resta, F., Casadio, M. C., Arcidiaco, M. C., Luvarà, M. C., Albertini, G., Di Lernia, V., Guareschi, E., Catrani, S., Morri, M., Amerio, P., De Simone, C., DʼAgostino, M., Agostino, I., Calvieri, S., Cantoresi, F., Richetta, A., Sorgi, P., Carnevale, C., Nicolucci, F., Berardesca, E., Ardigò, M., De Felice, C., Gubinelli, E., Talamonti, M., Camplone, G., Cruciani, G., Riccardi, F., Barbati, R., Pagani, W., Malagoli, P. G., Pellicano, R., Donadio, D., Di Vito, C., Cottoni, F., Montesu, M. A., Pirodda, C., Addis, G., Marongiu, P., Farris, A., Cacciapuoti, M., Verrini, A., Desirello, G., Gnone, M., Fimiani, M., Pellegrino, M., Castelli, G., Zappalà, L., Sesana, G., Ingordo, V., Vozza, E., Di Giuseppe, D., Fasciocco, D., Nespoli, P., Papini, M., Cicoletti, M., Bernengo, M. G., Ortoncelli, M., Bonvicino, A., Capella, G., Doveil, G. C., Forte, M., Peroni, A., Salomone, B., Savoia, P., Pippione, M., Zichichi, L., Frazzitta, M., De Luca, G., Tasin, L., Simonetto, D., Ros, S., Trevisan, G., Patamia, M., Miertusova, S., Patrone, P., Frattasio, A., Piccirillo, F., La Spina, S., Di Gaetano, L., Marzocchi, V., Motolese, A., Venturi, C., Gai, F., Pasquinucci, S., Bellazzi, R. M., Silvestri, T., Fornasa, Veller C., and Trevisan, G. P.
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- 2015
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36. Migrants’ activism for development: challenges and opportunities to sustainable agricultural development in Italy
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Miracapillo, Martina and Miracapillo, Martina
- Abstract
This qualitative case-study highlights the importance of the phenomenon of migration, under the aspect of civic activism of migrants, and its impact on Italian agricultural sustainable development. Migrants are too often seen as a burden rather than active agents of development. The present research investigates how political activism of migrants develops and eventually affects the sustainable development of the sector. It also focuses on the reason behind Italian workers inhibition towards protests against exploitation and indecent working conditions, in the agricultural fields. It analyses past protests, captures the voices of immigrants and local activists and their consequences on sustainable development. The results suggest that immigrant civic activism, even if limited in size, enhances development under different perspectives, particularly taking into consideration two arameters: Sustainable Development Goals 8 and 10. The strength of this study, is the added value of a spotlight on the differences between social groups in agricultural work exploitation, in this case natives and migrants. Through the investigation on their living and working conditions, the reasons which push them to collaborate or be in conflict in their activism for social change emerge.
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- 2021
37. Migrants’ activism for development: challenges and opportunities to sustainable agricultural development in Italy. The role of immigrant and local activists to achieve sustainable development through the fulfilment of SDG 8 and 10 in the agricultural sector
- Author
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Miracapillo, Martina and Miracapillo, Martina
- Abstract
This qualitative case-study highlights the importance of the phenomenon of migration, under the aspect of civic activism of migrants, and its impact on Italian agricultural sustainable development. Migrants are too often seen as a burden rather than active agents of development. The present research investigates how political activism of migrants develops and eventually affects the sustainable development of the sector. It also focuses on the reason behind Italian workers inhibition towards protests against exploitation and indecent working conditions, in the agricultural fields. It analyses past protests, captures the voices of immigrants and local activists and their consequences on sustainable development. The results suggest that immigrant civic activism, even if limited in size, enhances development under different perspectives, particularly taking into consideration two parameters: Sustainable Development Goals 8 and 10. The strength of this study, is the added value of a spotlight on the differences between social groups in agricultural work exploitation, in this case natives and migrants. Through the investigation on their living and working conditions, the reasons which push them to collaborate or be in conflict in their activism for social change emerge.
- Published
- 2021
38. Mortality after cardioverter-defibrillator replacement: Results of the DECODE survival score index
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Attilio Pierantozzi, Giovanni Licciardello, Maria Lucia Narducci, Biagio Sassone, Cristian Martignani, Sergio Setti, Gianfranco Ciaramitaro, T Infusino, Davide Caruso, Carlotta Terzaghi, Ernesto Ammendola, Pasquale Notarstefano, Leonardo Calò, V. Carinci, Gennaro Miracapillo, Mauro Biffi, C Ferretti, Massimo Zoni-Berisso, Maurizio Malacrida, and Mauro Zennaro
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Male ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Population ,Replacement ,Cardiac resynchronization therapy ,030204 cardiovascular system & hematology ,Prognostic index ,Implantable cardioverter-defibrillator ,NO ,Electrocardiography ,03 medical and health sciences ,0302 clinical medicine ,Interquartile range ,Physiology (medical) ,Internal medicine ,medicine ,Humans ,Prospective Studies ,030212 general & internal medicine ,education ,Shared decision making ,Aged ,Outcome ,Aged, 80 and over ,Heart Failure ,education.field_of_study ,Ischemic cardiomyopathy ,business.industry ,Proportional hazards model ,Middle Aged ,Defibrillators, Implantable ,Survival Rate ,Death, Sudden, Cardiac ,Italy ,Female ,Cardiology and Cardiovascular Medicine ,business ,Decision Making, Shared ,Body mass index ,Follow-Up Studies ,Cohort study - Abstract
Background Device replacement is the ideal time to reassess health care goals regarding continuing implantable cardioverter-defibrillator (ICD) therapy. Only few data are available on the decision making at this time. Objectives The goals of this study were to identify factors associated with poor prognosis at the time of ICD replacement and to develop a prognostic index able to stratify those patients at risk of dying early. Methods DEtect long-term COmplications after implantable cardioverter-DEfibrillator replacement (DECODE) was a prospective, single-arm, multicenter cohort study aimed at estimating long-term complications in a large population of patients who underwent ICD/cardiac resynchronization therapy – defibrillator replacement. Potential predictors of death were investigated, and all these factors were gathered into a survival score index (SUSCI). Results We included 983 consecutive patients (median age 71 years (63-78)); 750 (76%) were men, 537 (55%) had ischemic cardiomyopathy; 460 (47%) were implanted with cardiac resynchronization therapy – defibrillator. During a median follow-up period of 761 days (interquartile range 628–904 days), 114 patients (12%) died. In multivariate Cox regression analysis, New York Heart Association class III/IV, ischemic cardiomyopathy, body mass index Conclusion A simple score that includes a limited set of variables appears to be predictive of total mortality in an unselected real-world population undergoing ICD replacement. Evaluation of the patient’s profile may assist in predicting vulnerability and should prompt individualized options, especially for high-risk patients.
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- 2021
39. Cardiac resynchronization therapy defibrillators in patient with permanent atrial fibrillation
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Rapacciolo, A, Iacopino, S, D-Onofrio, A, Curnis, A, Pisan, Ec, Biffi, M, Della Bella, P, Dello Russo, A, Caravati, F, Zanotto, G, Calvi, V, Rovaris, G, Senatore, G, Nicolis, D, Santamaria, M, Gianmaria, M, Maglia, G, Duca, A, Ammirati, G, Romano, Sa, Piacenti, M, Celentano, E, Bisignani, G, Vaccaro, P, Miracapillo, G, Bertini, M, Nigro, G, Giacopelli, D, Gargaro, A, and Bisceglia, C
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- 2021
40. Cardiac resynchronization therapy defibrillators in patients with permanent atrial fibrillation
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Alessio Gargaro, Paolo Della Bella, Daniele Giacopelli, Salvo Andrea Romano, Giovanni Bisignani, Giampiero Maglia, Mauro Biffi, Antonio Curnis, Valeria Calvi, Ennio Pisano, Giovanni Rovaris, Eduardo Celentano, Fabrizio Caravati, Antonio Duca, Marcello Piacenti, Gennaro Miracapillo, Antonio Russo, Caterina Bisceglia, Antonio D'Onofrio, Gerardo Nigro, Giuseppe Ammirati, Daniele Nicolis, Paola Vaccaro, Saverio Iacopino, Gabriele Zanotto, Massimo Giammaria, Matteo Bertini, Gaetano Senatore, Antonio Rapacciuolo, and Matteo Santamaria
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Male ,medicine.medical_specialty ,Defibrillation ,medicine.medical_treatment ,Heart rate ,Cardiac resynchronization therapy ,Heart failure ,NO ,Internal medicine ,medicine ,Humans ,Diseases of the circulatory (Cardiovascular) system ,Sinus rhythm ,Aged ,Retrospective Studies ,Defibrillation shock ,business.industry ,Hazard ratio ,Atrial fibrillation ,Original Articles ,medicine.disease ,Confidence interval ,Treatment Outcome ,RC666-701 ,Cardiology ,Original Article ,Cardiology and Cardiovascular Medicine ,business ,Defibrillators - Abstract
Aims There are conflicting data on the benefit of cardiac resynchronization therapy (CRT) in heart failure (HF) patients with permanent atrial fibrillation (AF). We aimed to compare patient outcomes according to the presence or absence of permanent AF at device implantation. Methods and results We retrospectively analysed remote monitoring data from 1141 CRT defibrillators. Propensity score with inverse‐probability weighting method was used to balance AF and sinus rhythm (SR) groups. Analysis endpoints included total mortality, appropriate defibrillation shocks, and CRT percentage. There were 229 patients (20.1%) in the AF group and 912 patients (79.9%) in the SR group. Compared with SR patients, AF patients were older (median age, 77 vs. 72 years, P
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- 2021
41. Frequency and Significance of Right Atrial Appendage Thrombi in Patients with Persistent Atrial Fibrillation or Atrial Flutter
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Cresti, Alberto, García-Fernández, Miguel Angel, Miracapillo, Gennaro, Picchi, Andrea, Cesareo, Francesca, Guerrini, Francesco, and Severi, Silva
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- 2014
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42. Stepwise approach for visualization and reconstruction of pulmonary valve with intracardiac echocardiography
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De Sensi, Francesco, primary, Addonisio, Luigi, additional, Miracapillo, Gennaro, additional, Breschi, Marco, additional, Cresti, Alberto, additional, and Limbruno, Ugo, additional
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- 2021
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43. Pruritus characteristics in a large Italian cohort of psoriatic patients
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Damiani, G., Cazzaniga, S., Conic, R. R. Z., Naldi, L., Griseta, V., Miracapillo, A., Azzini, M., Mocci, L., Michelini, M., Offidani, A., Bernardini, L., Campanati, A., Ricotti, G., Giacchetti, A., Norat, M., Gualco, F., Castelli, A., Cuccia, A., Diana, A., Roncarolo, G., Belli, M. A., Baldassarre, M. A., Santoro, G., Vena, G. A., Lo Console, F., Filotico, R., Mastrandrea, V., Brunetti, B., Musumeci, F., Carrabba, E., Dal Mas, P., Annicchiarico, F., Benvegnu, B., Spaziani, G., Cusano, F., Saletta Iannazzone, S., Galluccio, A., Pezza, M., Marchesi, L., Imberti, G., Reseghetti, A., Barbera, C., Reggiani, M., Lanzoni, A., Patrizi, A., Bardazzi, F., Antonucci, A., De Tommaso, S., Wallnofer, W., Ingannamorte, F., Calzavara-Pinton, P., Iannazzi, S., Zane, C., Capezzera, R., Bassisi, S., Rossi, M. T., Altamura, V., Vigl, W., Nobile, C., Aste, N., Murgia, S., Mugheddu, C., Scuderi, G., Baglieri, F., Di Dio, C., Cilioni Grilli, E., Mastronardi, C., Agnusdei, C. P., Antrilli, A., Aulisa, L., Raimondo, U., Scotto di Luzio, G., Battarra, V. C., Farro, P., Plaitano, R., Micali, G., Musumeci, M. L., Massimino, D., Li Calzi, M., La Greca, S., Pettinato, M., Sapienza, G., Valenti, G., De Giacomo, P. F., Amico, Arcangeli, F., Brunelli, D., Ghetti, E., Tulli, A., Assi, G., Amerio, P., Laria, G., Prestinari, F., Spadafora, S., Coppola, M., Caresana, G., Pezzarossa, E., Felisi, C., Donato, L., Bertero, M., Musso, L., Pa lazzini, S., Bruscino, P., Agozzino, U. C., Ottaviani, M., Simoncini, C., Virgili, A., Osti, F., Fabbri, P., Volpi, W., Caproni, M., Lotti, T., Prignano, F., Buggiani, G., Troiano, M., Fenizi, G., Altobella, A., Amoruso, A., Condello, M., Goffredo, A., Righini, M. G., Alessandrini, F., Satolli, F., Zampetti, M., Bertani, E., Fossati, S., Parodi, A., Burlando, M., Fiorucci, C., Nigro, A., Ghigliotti, G., Massone, L., Moise, G. M., Serrai, M., Cannata, G., Campagnoli, A. M., Daly, M., Leporati, C., Peila, R., Filosa, G., Bugatti, L., Nicolini, M., Nazzari, G., Cestari, R., Anastasio, F., Larussa, F. M., Pollice, N., De Francesco, F., Mazzocchetti, G., Peris, K., Fargnoli, M. C., Di Cesare, A., De Angelis, L., Flati, G., Biamonte, A. S., Quarta, G., Congedo, M., Carcaterra, A., Strippoli, D., Fideli, D., Marsili, F., Celli, M., Ceccarini, M., Bachini, L., D'Oria, M., Schirripa, V., De Filippi, C., Martini, P., Lapucci, E., Mazzatenta, C., Ghilardi, A., Simonacci, M., Bettacchi, A., Gasco, R., Zanca, A., Battistini, S., Dattola, S., Vernaci, R., Postorino, F., Zampieri, P. F., Padovan, C., Gonzalez Intchaurraga, M. A., Ladurner, J., Guarneri, B., Cannavo, S., Manfre, C., Borgia, F., Puglisi Guerra, A., Cattaneo, A., Carrera, C., Fracchiolla, C., Mozzanica, N., Prezzemolo, L., Menni, S., Lodi, A., Martino, P., Monti, M., Mancini, L., Sacrini, F., Altomare, G. F., Taglioni, M., Lovati, C., Mercuri, S. R., Schiesari, G., Giannetti, A., Conti, A., Lasagni, C., Greco, M., Ronsini, G., Schianchi, S., Fiorentini, C., Niglietta, S., Maglietta, R., Padalino, C., Crippa, D., Pini, M., Rossi, E., Tosi, D., Armas, M., Ruocco, V., Ayala, F., Balato, N., Gaudiello, F., Cimmino, G. F., Monfrecola, G., Gallo, L., Argenziano, G., Fulgione, E., Berruti, G., Ceparano, S., De Michele, I., Giorgiano, D., Leigheb, G., Deledda, S., Peserico, A., Alaibac, M., Piaserico, S., Schiesari, L., Dan, G., Mattei, I., Oro, E., Arico, M., Bongiorno, M. R., Angileri, R., Amato, S., Todaro, F., Milioto, M., Bellastro, R., Di Nuzzo, S., De Panfilis, G., Zanni, M., Borroni, G., Cananzi, R., Brazzelli, V., Lisi, P., Stingeni, L., Hansel, K., Pierfelice, V., Donelli, S., Rastelli, D., Gasperini, M., Barachini, P., Cecchi, R., Bartoli, L., Pavesi, M., De Paola, S., Corradin, M. T., Ricciuti, F., Piccirillo, A., Viola, L., Tataranni, M., Mautone, M. G., Lo Scocco, G., Niccoli, M. C., Brunasso Vernetti, A. M. G., Gaddoni, G., Resta, F., Casadio, M. C., Arcidiaco, M. C., Luvara, M. C., Albertini, G., Di Lernia, V., Guareschi, E., Catrani, S., Morri, M., De Simone, C., D'Agostino, M., Agostino, I., Calvieri, S., Cantoresi, F., Richetta, A., Sorgi, P., Carnevale, C., Nicolucci, F., Berardesca, E., Ardigo, M., De Felice, C., Gubinelli, E., Talamonti, M., Camplone, G., Cruciani, G., Riccardi, F., Barbati, R., Zumiani, G., Pagani, W., Malagoli, P. G., Pellicano, R., Donadio, D., Di Vito, C., Cottoni, F., Montesu, M. A., Pirodda, C., Addis, G., Marongiu, P., Farris, A., Cacciapuoti, M., Verrini, A., Desirello, G., Gnone, M., Fimiani, M., Pellegrino, M., Castelli, G., Zappala, L., Sesana, G., Ingordo, V., Vozza, E., Di Giuseppe, D., Fasciocco, D., Nespoli, P., Papini, M., Cicoletti, M., Bernengo, M. G., Ortoncelli, M., Bonvicino, A., Capella, G., Doveil, G. C., Forte, M., Peroni, A., Salomone, B., Savoia, P., Pippione, M., Zichichi, L., Frazzitta, M., De Luca, G., Tasin, L., Simonetto, D., Ros, S., Trevisan, G., Patamia, M., Miertusova, S., Patrone, P., Frattasio, A., Piccirillo, F., La Spina, S., Di Gaetano, L., Marzocchi, V., Motolese, A., Venturi, C., Gai, F., Pasquinucci, S., Bellazzi, R. M., Silvestri, T., Girolomoni, G., Gisondi, P., Veller Fornasa, C., Trevisan, G. P., Damiani G., Cazzaniga S., Conic R.R.Z., Naldi L., Griseta V., Miracapillo A., Azzini M., Mocci L., Michelini M., Offidani A., Bernardini L., Campanati A., Ricotti G., Giacchetti A., Norat M., Gualco F., Castelli A., Cuccia A., Diana A., Roncarolo G., Belli M.A., Baldassarre M.A., Santoro G., Vena G.A., Lo Console F., Filotico R., Mastrandrea V., Brunetti B., Musumeci F., Carrabba E., Dal Mas P., Annicchiarico F., Benvegnu B., Spaziani G., Cusano F., Saletta Iannazzone S., Galluccio A., Pezza M., Marchesi L., Imberti G., Reseghetti A., Barbera C., Reggiani M., Lanzoni A., Patrizi A., Bardazzi F., Antonucci A., De Tommaso S., Wallnofer W., Ingannamorte F., Calzavara-Pinton P., Iannazzi S., Zane C., Capezzera R., Bassisi S., Rossi M.T., Altamura V., Vigl W., Nobile C., Aste N., Murgia S., Mugheddu C., Scuderi G., Baglieri F., Di Dio C., Cilioni Grilli E., Mastronardi C., Agnusdei C.P., Antrilli A., Aulisa L., Raimondo U., Scotto di Luzio G., Battarra V.C., Farro P., Plaitano R., Micali G., Musumeci M.L., Massimino D., Li Calzi M., La Greca S., Pettinato M., Sapienza G., Valenti G., De Giacomo P.F., Amico, Arcangeli F., Brunelli D., Ghetti E., Tulli A., Assi G., Amerio P., Laria G., Prestinari F., Spadafora S., Coppola M., Caresana G., Pezzarossa E., Felisi C., Donato L., Bertero M., Musso L., Pa lazzini S., Bruscino P., Agozzino U.C., Ottaviani M., Simoncini C., Virgili A., Osti F., Fabbri P., Volpi W., Caproni M., Lotti T., Prignano F., Buggiani G., Troiano M., Fenizi G., Altobella A., Amoruso A., Condello M., Goffredo A., Righini M.G., Alessandrini F., Satolli F., Zampetti M., Bertani E., Fossati S., Parodi A., Burlando M., Fiorucci C., Nigro A., Ghigliotti G., Massone L., Moise G.M., Serrai M., Cannata G., Campagnoli A.M., Daly M., Leporati C., Peila R., Filosa G., Bugatti L., Nicolini M., Nazzari G., Cestari R., Anastasio F., Larussa F.M., Pollice N., De Francesco F., Mazzocchetti G., Peris K., Fargnoli M.C., Di Cesare A., De Angelis L., Flati G., Biamonte A.S., Quarta G., Congedo M., Carcaterra A., Strippoli D., Fideli D., Marsili F., Celli M., Ceccarini M., Bachini L., D'Oria M., Schirripa V., De Filippi C., Martini P., Lapucci E., Mazzatenta C., Ghilardi A., Simonacci M., Bettacchi A., Gasco R., Zanca A., Battistini S., Dattola S., Vernaci R., Postorino F., Zampieri P.F., Padovan C., Gonzalez Intchaurraga M.A., Ladurner J., Guarneri B., Cannavo S., Manfre C., Borgia F., Puglisi Guerra A., Cattaneo A., Carrera C., Fracchiolla C., Mozzanica N., Prezzemolo L., Menni S., Lodi A., Martino P., Monti M., Mancini L., Sacrini F., Altomare G.F., Taglioni M., Lovati C., Mercuri S.R., Schiesari G., Giannetti A., Conti A., Lasagni C., Greco M., Ronsini G., Schianchi S., Fiorentini C., Niglietta S., Maglietta R., Padalino C., Crippa D., Pini M., Rossi E., Tosi D., Armas M., Ruocco V., Ayala F., Balato N., Gaudiello F., Cimmino G.F., Monfrecola G., Gallo L., Argenziano G., Fulgione E., Berruti G., Ceparano S., De Michele I., Giorgiano D., Leigheb G., Deledda S., Peserico A., Alaibac M., Piaserico S., Schiesari L., Dan G., Mattei I., Oro E., Arico M., Bongiorno M.R., Angileri R., Amato S., Todaro F., Milioto M., Bellastro R., Di Nuzzo S., De Panfilis G., Zanni M., Borroni G., Cananzi R., Brazzelli V., Lisi P., Stingeni L., Hansel K., Pierfelice V., Donelli S., Rastelli D., Gasperini M., Barachini P., Cecchi R., Bartoli L., Pavesi M., De Paola S., Corradin M.T., Ricciuti F., Piccirillo A., Viola L., Tataranni M., Mautone M.G., Lo Scocco G., Niccoli M.C., Brunasso Vernetti A.M.G., Gaddoni G., Resta F., Casadio M.C., Arcidiaco M.C., Luvara M.C., Albertini G., Di Lernia V., Guareschi E., Catrani S., Morri M., De Simone C., D'Agostino M., Agostino I., Calvieri S., Cantoresi F., Richetta A., Sorgi P., Carnevale C., Nicolucci F., Berardesca E., Ardigo M., De Felice C., Gubinelli E., Talamonti M., Camplone G., Cruciani G., Riccardi F., Barbati R., Zumiani G., Pagani W., Malagoli P.G., Pellicano R., Donadio D., Di Vito C., Cottoni F., Montesu M.A., Pirodda C., Addis G., Marongiu P., Farris A., Cacciapuoti M., Verrini A., Desirello G., Gnone M., Fimiani M., Pellegrino M., Castelli G., Zappala L., Sesana G., Ingordo V., Vozza E., Di Giuseppe D., Fasciocco D., Nespoli P., Papini M., Cicoletti M., Bernengo M.G., Ortoncelli M., Bonvicino A., Capella G., Doveil G.C., Forte M., Peroni A., Salomone B., Savoia P., Pippione M., Zichichi L., Frazzitta M., De Luca G., Tasin L., Simonetto D., Ros S., Trevisan G., Patamia M., Miertusova S., Patrone P., Frattasio A., Piccirillo F., La Spina S., Di Gaetano L., Marzocchi V., Motolese A., Venturi C., Gai F., Pasquinucci S., Bellazzi R.M., Silvestri T., Girolomoni G., Gisondi P., Veller Fornasa C., and Trevisan G.P.
- Subjects
Male ,Cross-sectional study ,Severity of Illness Index ,Cohort Studies ,030207 dermatology & venereal diseases ,0302 clinical medicine ,Risk Factors ,education ,itch ,pruritus ,psoriasis ,pustular psoriasis ,treatment ,Adolescent ,Adult ,Cross-Sectional Studies ,Educational Status ,Facial Dermatoses ,Female ,Foot Dermatoses ,Genitalia ,Hand Dermatoses ,Humans ,Italy ,Middle Aged ,Pruritus ,Psoriasis ,Registries ,Sex Factors ,Young Adult ,Epidemiology ,Young adult ,skin and connective tissue diseases ,Settore MED/33 - MALATTIE APPARATO LOCOMOTORE ,Infectious Diseases ,030220 oncology & carcinogenesis ,Cohort ,PRURITIS EPIDEMIOLOGY ,Settore MED/35 - MALATTIE CUTANEE E VENEREE ,Cohort study ,medicine.medical_specialty ,PSORIAS ,Dermatology ,Article ,03 medical and health sciences ,Pharmacotherapy ,Settore MED/35 ,Severity of illness ,medicine ,business.industry ,medicine.disease ,Pruritus,Itch sensation ,business - Abstract
Background: Psoriasis (Ps) is a chronic systemic autoimmune disease associated with pruritus in 64–98% of patients. However, few modestly sized studies assess factors associated with psoriatic pruritus. Objective: To investigate factors associated with Ps pruritus intensity. Methods: Psoriasis patients 18years or older seen in one of 155 centres in Italy between September 2005 and 2009 were identified from the Italian PsoCare registry. Patients without cutaneous psoriasis and those with missed information on pruritus were excluded. Results: We identified 10802 patients, with a mean age 48.8±14.3years. Mild itch was present in 33.2% of patients, moderate in 34.4%, severe in 18.7% and very severe in 13.7%. Higher itch intensity was associated with female gender, lower educational attainment compared to university degree, pustular psoriasis, psoriasis on the head, face, palmoplantar areas, folds and genitalia, more severe disease, disease duration
- Published
- 2019
44. Oral Abstract sessionImaging in structural interventions: 13/12/2013, 08: 30–10: 00Location: Bursa
- Author
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Cresti, A, Cesareo, F, Guerrini, F, Capati, E, Miracapillo, G, and Severi, S
- Published
- 2013
45. How to visualize and reconstruct the pulmonary valve and contiguous structures with intracardiac echocardiography: a simplified multi-step approach
- Author
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Ugo Limbruno, Gennaro Miracapillo, Luigi Addonisio, Paolo Orselli, Marco Breschi, Francesco De Sensi, and Alberto Cresti
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Aortic valve ,medicine.medical_specialty ,Radiofrequency ablation ,business.industry ,Ventricular tachycardia ,medicine.disease ,Intracardiac injection ,law.invention ,Coronary arteries ,medicine.anatomical_structure ,law ,medicine.artery ,Internal medicine ,Pulmonary valve ,Pulmonary artery ,cardiovascular system ,medicine ,Cardiology ,Ventricular outflow tract ,cardiovascular diseases ,business - Abstract
Ventricular tachycardia and premature ventricular complexes (PVCs) arising from right ventricular outflow tract (RVOT) are the most common type of ventricular arrhythmias (VAs) in patients without structural heart disease. Radiofrequency ablation is now the gold standard of treatment in this setting due to high efficacy rates and optimal safety profile [2] During the last few years, the pulmonary valve (PV) and the pulmonary artery (PA) have attracted much attention as reliable sites of origin of RVOT-type arrhythmias. In the mean while intracardiac echocardiogram (ICE) has undoubtedly improved our understanding and approach to manage these arrhythmias accurately characterizing the PV and its contiguous structures. Aim of this paper is to provide an illustrated step-by-step guide on how to use ICE with the CARTOSOUND module to visualize and reconstruct 3D shell of the RV, the PV, as well of other anatomical structures (i.e., the aortic valve and coronary arteries) to perform aware and safe ablation in this region. A new reconsideration of the existent classification of these VAs is also provided.
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- 2020
46. Treatment of Psoriasis Vulgaris with the Two-Compound Product Calcipotriol/Betamethasone Dipropionate followed by Different Formulations of Calcipotriol
- Author
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Cassano, Nicoletta, Miracapillo, Antonio, Coviello, Carmela, Loconsole, Francesco, Bellino, Marco, and Vena, Gino Antonio
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- 2006
- Full Text
- View/download PDF
47. Achilles’ heel of integrated hydrologic models: The stream-aquifer flow exchange, and proposed alternative
- Author
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Hubert J. Morel-Seytoux, Calvin D. Miller, Cinzia Miracapillo, and Steffen Mehl
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geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Petroleum engineering ,Hydrological modelling ,0208 environmental biotechnology ,Aquifer ,02 engineering and technology ,01 natural sciences ,020801 environmental engineering ,Regional studies ,Environmental science ,Conjunctive use ,Groundwater ,0105 earth and related environmental sciences ,Water Science and Technology - Abstract
Due to the dynamic flow exchange between a stream and a connected water- table aquifer, a physically based hydrologic model is an important tool for the design of conjunctive use of surface and ground waters. It is needed to develop sound plans for sustainable use of the groundwater with minimal undesirable effects. This article reports an investigation of the component (module) that describes the stream-aquifer flow exchange in several groundwater simulators. The study indicates that the module may not have a solid physical basis when used in large-scale regional studies to estimate the stream-aquifer flow exchange. The component relies upon an empirical parameter known as the leakance coefficient. It is demonstrated that neglecting river penetration of the aquifer can lead to non-negligible errors in estimation of seepage. In addition the leakance coefficient (dimension inverse of a time) is not constant in time but varies with the conditions in the river and in the surrounding aquifer. A potential, practical and simple alternative is presented.
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- 2018
48. P5238Rate, cause and costs of Heart Failure hospitalizations following ICD/CRT-D replacement: preliminary data from an Italian multicenter registry
- Author
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C Ferretti, V. Carinci, Gennaro Miracapillo, M. Zoni Berisso, Francesco Zanon, Pasquale Notarstefano, L Calo, Maurizio Malacrida, A. Del Rosso, Valerio Zacà, M L Narducci, Fabio Quartieri, Quintino Parisi, Davide Saporito, and Mauro Biffi
- Subjects
medicine.medical_specialty ,business.industry ,Heart failure ,Emergency medicine ,Medicine ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Abstract
Background Heart failure hospitalizations (HFHs) likely represent the main health care expenditure also in implantable cardiac defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-D) recipients yet the event rate of HFH and the associated costs after device replacement or upgrade are unknown. Purpose To report HFH rates and associated costs within 12 months following ICD/CRT-D device replacement or upgrade procedure from ICD to CRT-D. Methods The DEtect long-term COmplications after icD rEplacement (DECODE) was a prospective, single-arm, multicenter cohort study exploring complications in ICD/CRT-D recipients undergoing device replacement or upgrade from ICD to CRT-D. All clinical and survival data of these patients at 12-month follow-up were prospectively analyzed. For each adjudicated HFH, the admission and discharge date were recorded, and ICD-9-CM diagnoses and procedure codes were obtained. The estimated reimbursement for each hospitalization was calculated according to the 2012 Italian national reimbursement rates. Results Between 2013 and 2015, 983 patients (mean age = 71 years, mean LVEF = 35%, NYHA class I/II = 75.6%) were enrolled: 900 (91.6%) patients underwent device replacement (446 ICD/454 CRT-D) and 83 (8.4%) upgrade from ICD to CRT-D. After 12 months, 66 (6.7%) patients died, 40 (60.6%) for cardiovascular reasons. Fifty-five (5.6%) patients experienced at least 1 HFH. Overall, 91 HFH (9.6% event rate 95% CI, 7.7–11.7) occurred. Among the variables tested at univariate analysis, only LVEF ≤35%, AF history and renal disease were confirmed as HFH predictors at multivariate analysis. HFH rate was significantly higher following upgrade procedures and occurrence of HFH was associated with an eleven-fold increased mortality risk (95% CI: 5.9 to 20.5; p Conclusion Underlying cardiac disease and renal failure are the main drivers of HFH and mortality, and of higher healthcare expenditures in ICD/CRT-D recipients following device replacement or upgrade. Accurate clinical assessment is needed to support the decision-maker at the time of ICD replacement to take an appropriate clinical and economic sustainable decision. Acknowledgement/Funding None
- Published
- 2019
49. LEFT AXILLARY LOOP RECORDER IMPLANTATION: LONG-TERM F-UP: 29.5
- Author
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Miracapillo, G., Addonisio, L., Costoli, A., Breschi, M., Corbucci, G., and Severi, S.
- Published
- 2011
50. What is the role of the uncinate fasciculus? Surgical removal and proper name retrieval
- Author
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Papagno, Costanza, Miracapillo, Christiano, Casarotti, Alessandra, Romero Lauro, Leonor J., Castellano, Antonella, Falini, Andrea, Casaceli, Giuseppe, Fava, Enrica, and Bello, Lorenzo
- Published
- 2011
- Full Text
- View/download PDF
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