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358 results on '"Mirzaei, Sepideh"'

1. miRNAs as short non-coding RNAs in regulating doxorubicin resistance

Author

Mirzaei, Sepideh, Paskeh, Mahshid Deldar Abad, Moghadam, Farhad Adhami, Entezari, Maliheh, Koohpar, Zeinab Khazaei, Hejazi, Elahe Sadat, Rezaei, Shamin, kakavand, Amirabbas, Aboutalebi, Maryam, Zandieh, Mohammad Arad, Rajabi, Romina, Salimimoghadam, Shokooh, Taheriazam, Afshin, Hashemi, Mehrdad, and Samarghandian, Saeed

Published
2023
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2. Deciphering STAT3 signaling potential in hepatocellular carcinoma: tumorigenesis, treatment resistance, and pharmacological significance

Author

Hashemi, Mehrdad, Sabouni, Eisa, Rahmanian, Parham, Entezari, Maliheh, Mojtabavi, Mahsa, Raei, Behnaz, Zandieh, Mohammad Arad, Behroozaghdam, Mitra, Mirzaei, Sepideh, Hushmandi, Kiavash, Nabavi, Noushin, Salimimoghadam, Shokooh, Ren, Jun, Rashidi, Mohsen, Raesi, Rasoul, Taheriazam, Afshin, Alexiou, Athanasios, Papadakis, Marios, and Tan, Shing Cheng

Published
2023
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4. siRNA and targeted delivery systems in breast cancer therapy

Author

Mirzaei, Sepideh, Paskeh, Mahshid Deldar Abad, Entezari, Maliheh, Bidooki, Seyed Hesamoddin, Ghaleh, Vahideh Javadian, rezaei, Shamin, Hejazi, Elahe Sadat, Kakavand, Amirabbas, Behroozaghdam, Mitra, Movafagh, Abolfazl, Taheriazam, Afshin, Hashemi, Mehrdad, and Samarghandian, Saeed

Published
2023
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17. Targeting PI3K/Akt signaling in prostate cancer therapy

Author

Hashemi, Mehrdad, Taheriazam, Afshin, Daneii, Pouria, Hassanpour, Aria, kakavand, Amirabbas, Rezaei, Shamin, Hejazi, Elahe Sadat, Aboutalebi, Maryam, Gholamrezaie, Hamidreza, Saebfar, Hamidreza, Salimimoghadam, Shokooh, Mirzaei, Sepideh, Entezari, Maliheh, and Samarghandian, Saeed

Published
2022
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18. Unraveling the function of epithelial-mesenchymal transition (EMT) in colorectal cancer: Metastasis, therapy response, and revisiting molecular pathways

Author

Sabouni, Eisa, Nejad, Melina Maghsodlou, Mojtabavi, Sarah, Khoshdooz, Sara, Mojtabavi, Mahsa, Nadafzadeh, Niloufar, Nikpanjeh, Negin, Mirzaei, Sepideh, Hashemi, Mehrdad, Aref, Amir Reza, Khorrami, Ramin, Nabavi, Noushin, Ertas, Yavuz Nuri, Salimimoghadam, Shokooh, Zandieh, Mohammad Arad, Rahmanian, Parham, Taheriazam, Afshin, and Hushmandi, Kiavash

Published
2023
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21. Graphene oxide nanoarchitectures in cancer biology: Nano-modulators of autophagy and apoptosis

Author

Taheriazam, Afshin, Abad, Ghazaleh Gholamiyan Yousef, Hajimazdarany, Shima, Imani, Mohammad Hassan, Ziaolhagh, Setayesh, Zandieh, Mohammad Arad, Bayanzadeh, Seyedeh Delaram, Mirzaei, Sepideh, Hamblin, Michael R., Entezari, Maliheh, Aref, Amir Reza, Zarrabi, Ali, Ertas, Yavuz Nuri, Ren, Jun, Rajabi, Romina, Paskeh, Mahshid Deldar Abad, Hashemi, Mehrdad, and Hushmandi, Kiavash

Published
2023
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27. Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

Author

Paskeh, Mahshid Deldar Abad, Entezari, Maliheh, Mirzaei, Sepideh, Zabolian, Amirhossein, Saleki, Hossein, Naghdi, Mohamad Javad, Sabet, Sina, Khoshbakht, Mohammad Amin, Hashemi, Mehrdad, Hushmandi, Kiavash, Sethi, Gautam, Zarrabi, Ali, Kumar, Alan Prem, Tan, Shing Cheng, Papadakis, Marios, Alexiou, Athanasios, Islam, Md Asiful, Mostafavi, Ebrahim, and Ashrafizadeh, Milad

Published
2022
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41. Nanoliposomes as nonviral vectors in cancer gene therapy.

Author

Yildiz, Safiye Nur, Entezari, Maliheh, Paskeh, Mahshid Deldar Abad, Mirzaei, Sepideh, Kalbasi, Alireza, Zabolian, Amirhossein, Hashemi, Farid, Hushmandi, Kiavash, Hashemi, Mehrdad, Raei, Mehdi, Goharrizi, Mohammad Ali Sheikh Beig, Aref, Amir Reza, Zarrabi, Ali, Ren, Jun, Orive, Gorka, Rabiee, Navid, and Ertas, Yavuz Nuri

Subjects
CANCER genes, GENE therapy, CANCER treatment, GENETIC vectors, LIPOSOMES, GENETIC carriers
Abstract

Nonviral vectors, such as liposomes, offer potential for targeted gene delivery in cancer therapy. Liposomes, composed of phospholipid vesicles, have demonstrated efficacy as nanocarriers for genetic tools, addressing the limitations of off‐targeting and degradation commonly associated with traditional gene therapy approaches. Due to their biocompatibility, stability, and tunable physicochemical properties, they offer potential in overcoming the challenges associated with gene therapy, such as low transfection efficiency and poor stability in biological fluids. Despite these advancements, there remains a gap in understanding the optimal utilization of nanoliposomes for enhanced gene delivery in cancer treatment. This review delves into the present state of nanoliposomes as carriers for genetic tools in cancer therapy, sheds light on their potential to safeguard genetic payloads and facilitate cell internalization alongside the evolution of smart nanocarriers for targeted delivery. The challenges linked to their biocompatibility and the factors that restrict their effectiveness in gene delivery are also discussed along with exploring the potential of nanoliposomes in cancer gene therapy strategies by analyzing recent advancements and offering future directions. [ABSTRACT FROM AUTHOR]

Published
2024
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43. Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression

Author

Ashrafizadeh, Milad, Mirzaei, Sepideh, Gholami, Mohammad Hossein, Hashemi, Farid, Zabolian, Amirhossein, Raei, Mehdi, Hushmandi, Kiavash, Zarrabi, Ali, Voelcker, Nicolas H., Aref, Amir Reza, Hamblin, Michael R., Varma, Rajender S., Samarghandian, Saeed, Arostegi, I.J., Alzola, M., Kumar, Alan Prem, Thakur, Vijay Kumar, Nabavi, Noushin, Makvandi, Pooyan, Tay, Franklin R., and Orive, Gorka

Published
2021
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49. National and Subnational Incidence Trend of Bladder Cancer in Iran: Report of a 12-Year Period.

Author

Nowroozi, Mohammad Reza, Amini, Erfan, Farkhani, Ehsan Mosa, Nowroozi, Ali, Ayati, Mohsen, Momeni, Seyed Ali, Mirzaei, Sepideh, Hushmandi, Kiavash, Sharifi, Laleh, and Bokaie, Saied

Subjects
BLADDER tumors, RESEARCH, RESEARCH methodology, AGE distribution, POPULATION geography, DISEASE incidence, SEX distribution, CANCER patients, TIME series analysis, DESCRIPTIVE statistics, RESEARCH funding
Abstract

Background: Bladder cancer is one of the most common cancers worldwide and also in Iran. Understanding of bladder cancer epidemiology is of great value for policymakers and assists in the prevention and early detection of the disease. Objectives: The aim of the present study was to report national and subnational incidence trends of bladder cancer in Iran between 2003 and 2015. Methods: This study investigated the age-standardized incidence rates (ASIRs) per annum of bladder cancer from 2003 to 2015 in Iran using the data from the cancer registration system of the Ministry of Health and Medical Education of Iran. The crude incidence rates were calculated by dividing incident cases by the country and province population, which were provided by the Statistic Center of Iran. Age standardization was performed using the WHO standard population, and ASIRs were compared by age, sex, and province. Results: The ASIR of bladder cancer increased from 8.35 in 2003 to 13.57 in 2015 in men. The ASIR of bladder cancer also showed a mild increase in females, 2.12 in 2003 versus 2.86 in 2015. The province of Yazd had the highest rate of bladder cancer in men, and West Azerbaijan had the highest rate for women (15.13 and 7.79 per 100,000), while Sistan va Baluchestan and Ilam had the lowest ASIRs formen and women (3.01 and 0.96 per 100,000, respectively). Conclusions: The increasing trend of bladder cancer incidence in Iran, despite the clear decreasing global trend accompanying to ongoing aging of the population highlights the diseases as a potential health problem in the upcoming years in Iran. Therefore, it is necessary for health organizations to implement effective research and control programs in the country to prevent further increases in disease burden. [ABSTRACT FROM AUTHOR]

Published
2023
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50. The potential immunomodulatory effect of levamisole in humans and farm animals.

Author

Gholami, Mohammad Hossein, Rassouli, Ali, Mirzaei, Sepideh, and Hashemi, Farid

Subjects
LEVAMISOLE, LITERATURE reviews, ANIMAL species, DIETARY supplements, DATABASE searching
Abstract

This study conducted a literature review to investigate the immunomodulatory effect of levamisole in both humans and farm animals. The following procedure was followed for database searching: PubMed, Google Scholar, Web of Science, and Cochrane Library. All research works were updated to September 2022. The terms used in the literature search were included: ("levamisole" OR "immunity" OR "immune system") AND ("adjuvant" OR "fish" OR "poultry" OR "farm animal" OR "cattle" OR "sheep"). The current review enlightens the extensive potential of levamisole as an adjuvant immunotherapeutic agent and explains its divergent applications beyond its antiparasitic use as an adjuvant, dietary supplement, immunostimulant, antiviral, and anti-cancer drug in humans and farm animals. In the articles examined, various mechanisms have been proposed for levamisole immunoprotective effects, but hormonal alteration and stress hormone reduction are indicated as the main mechanisms in various animal species. [ABSTRACT FROM AUTHOR]

Published
2023
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