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138 results on '"Misciagna, Giovanni"'

2. Development and validation of a neural network for NAFLD diagnosis

Author

Sorino, Paolo, Campanella, Angelo, Bonfiglio, Caterina, Mirizzi, Antonella, Franco, Isabella, Bianco, Antonella, Caruso, Maria Gabriella, Misciagna, Giovanni, Aballay, Laura R., Buongiorno, Claudia, Liuzzi, Rosalba, Cisternino, Anna Maria, Notarnicola, Maria, Chiloiro, Marisa, Fallucchi, Francesca, Pascoschi, Giovanni, and Osella, Alberto Rubén

Published
2021
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11. Modified WCRF/AICR Score and All-Cause, Digestive System, Cardiovascular, Cancer and Other-Cause-Related Mortality: A Competing Risk Analysis of Two Cohort Studies Conducted in Southern Italy

Author

Mirizzi, Antonella, primary, Aballay, Laura R., additional, Misciagna, Giovanni, additional, Caruso, Maria G., additional, Bonfiglio, Caterina, additional, Sorino, Paolo, additional, Bianco, Antonella, additional, Campanella, Angelo, additional, Franco, Isabella, additional, Curci, Ritanna, additional, Procino, Filippo, additional, Cisternino, Anna M., additional, Notarnicola, Maria, additional, D’Aprile, Pierina F., additional, and Osella, Alberto R., additional

Published
2021
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12. Effects of weight change on all causes, digestive system and other causes mortality in Southern Italy: a competing risk approach

Author

Campanella, Angelo, primary, Sorino, Paolo, additional, Bonfiglio, Caterina, additional, Mirizzi, Antonella, additional, Franco, Isabella, additional, Bianco, Antonella, additional, Misciagna, Giovanni, additional, Caruso, Maria Gabriella, additional, Cisternino, Anna Maria, additional, Notarnicola, Maria, additional, Tutino, Valeria, additional, D’Attoma, Benedetta, additional, and Osella, Alberto Ruben, additional

Published
2021
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13. The effect of the Mediterranean Diet on lifespan: a treatment-effect survival analysis of a population-based prospective cohort study in Southern Italy

Author

Campanella, Angelo, primary, Misciagna, Giovanni, additional, Mirizzi, Antonella, additional, Caruso, Maria Gabriella, additional, Bonfiglio, Caterina, additional, Aballay, Laura R, additional, Vas de Arruda Silveira, Liciana, additional, Bianco, Antonella, additional, Franco, Isabella, additional, Sorino, Paolo, additional, Buongiorno, Claudia, additional, Cisternino, Anna Maria, additional, Notarnicola, Maria, additional, Guerra, Vito M B, additional, and Osella, Alberto R, additional

Published
2020
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14. Remnant cholesterol as a risk factor for cardiovascular, cancer or other causes mortality: A competing risks analysis

Author

Bonfiglio, Caterina, primary, Leone, Carla M., additional, Silveira, Liciana V.A., additional, Guerra, Rocco, additional, Misciagna, Giovanni, additional, Caruso, Maria G., additional, Bruno, Irene, additional, Buongiorno, Claudia, additional, Campanella, Angelo, additional, Guerra, Vito M.B., additional, Notarnicola, Maria, additional, Deflorio, Valentina, additional, Franco, Isabella, additional, Bianco, Antonella, additional, Mirizzi, Antonella, additional, Aballay, Laura R., additional, Cisternino, Anna M., additional, Sorino, Paolo, additional, Pesole, Pasqua L., additional, and Osella, Alberto R., additional

Published
2020
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15. The Effect of Three Mediterranean Diets on Remnant Cholesterol and Non-Alcoholic Fatty Liver Disease: A Secondary Analysis

Author

Campanella, Angelo, primary, Iacovazzi, Palma A., additional, Misciagna, Giovanni, additional, Bonfiglio, Caterina, additional, Mirizzi, Antonella, additional, Franco, Isabella, additional, Bianco, Antonella, additional, Sorino, Paolo, additional, Caruso, Maria G., additional, Cisternino, Anna M., additional, Buongiorno, Claudia, additional, Liuzzi, Rosalba, additional, and Osella, Alberto R., additional

Published
2020
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16. Traditional Dietary Patterns and Risk of Mortality in a Longitudinal Cohort of the Salus in Apulia Study

Author

Zupo, Roberta, primary, Sardone, Rodolfo, additional, Donghia, Rossella, additional, Castellana, Fabio, additional, Lampignano, Luisa, additional, Bortone, Ilaria, additional, Misciagna, Giovanni, additional, De Pergola, Giovanni, additional, Panza, Francesco, additional, Lozupone, Madia, additional, Passantino, Andrea, additional, Veronese, Nicola, additional, Guerra, Vito, additional, Boeing, Heiner, additional, and Giannelli, Gianluigi, additional

Published
2020
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17. Trends in adherence to the Mediterranean diet in South Italy: A cross sectional study

Author

Veronese, Nicola, primary, Notarnicola, Maria, additional, Cisternino, Anna M., additional, Inguaggiato, Rosa, additional, Guerra, Vito, additional, Reddavide, Rosa, additional, Donghia, Rossella, additional, Rotolo, Ornella, additional, Zinzi, Iris, additional, Leandro, Gioacchino, additional, Tutino, Valeria, additional, Misciagna, Giovanni, additional, Caruso, Maria G., additional, Correale, Mario, additional, Giampiero, De Michele, additional, Anna, Mastrosimini, additional, Palma, Iacovazzi, additional, Marisa, Noviello, additional, Chiloiro, Marisa, additional, Osvaldo, Burattini, additional, Vittorio, Pugliese, additional, and D'Attoma, Benedetta, additional

Published
2020
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19. Increased serum levels of lipogenic enzymes in patients with severe liver steatosis

Author

Notarnicola Maria, Misciagna Giovanni, Tutino Valeria, Chiloiro Marisa, Osella Alberto, Guerra Vito, Bonfiglio Caterina, and Caruso Maria

Subjects
Fatty acid synthase, Lipoprotein lipase, Liver steatosis, Enzyme activity, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Abstract Background Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liver. Lipoprotein lipase (LPL), the rate-limiting enzyme for the hydrolysis of core triglycerides, plays a pivotal role in lipid metabolism. This study aims to investigate if circulating levels of FAS and LPL could be clinically associated with liver steatosis. Methods In this work, we present data obtained from a subsample of 94 subjects with liver steatosis enrolled by NUTRIEPA study, a nutritional trial in subjects with liver steatosis. Serum levels of FAS protein and LPL activity were evaluated by ELISA test and by a fluorescent method, respectively. The diagnosis and the degree of liver steatosis were based on laboratory and ecographic measurements. Statistical methods included Kruskal-Wallis analysis of variance and Wilcoxon signed-rank test, where appropriate. The χ2 test has been performed to analyse categorical variables. Results The subjects with severe steatosis had significantly higher serum levels of FAS protein and LPL activity compared to subjects with mild and moderate liver steatosis. Moreover, a positive trend in serum levels of FAS expression from lower to higher degree of steatosis was also detected. Conclusions We describe a relationship between human liver steatosis and elevated levels of circulating lipogenic enzymes. Increased serum levels of FAS expression and LPL activity could be considered a marker of severe liver steatosis.

Published
2012
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20. The effect of the Mediterranean Diet on lifespan: a treatment-effect survival analysis of a population-based prospective cohort study in Southern Italy.

Author

Campanella, Angelo, Misciagna, Giovanni, Mirizzi, Antonella, Caruso, Maria Gabriella, Bonfiglio, Caterina, Aballay, Laura R, Silveira, Liciana Vas de Arruda, Bianco, Antonella, Franco, Isabella, Sorino, Paolo, Buongiorno, Claudia, Cisternino, Anna Maria, Notarnicola, Maria, Guerra, Vito M B, Osella, Alberto R, and Vas de Arruda Silveira, Liciana

Subjects
*MEDITERRANEAN diet, *SURVIVAL analysis (Biometry), *LONGITUDINAL method, *COHORT analysis, *TREATMENT effectiveness, *CONFIDENCE intervals
Abstract

Background: The Mediterranean diet (MedDiet) is associated with good health. We aimed to estimate the effect of levels of adherence to the MedDiet on lifespan by performing treatment effects survival analysis.Methods: A sample of 5250 subjects aged ≥18 years were randomly selected from the electoral list of Castellana Grotte and Putignano (Apulian Region, Italy). Cohorts were enrolled in 2005-06 and followed-up until December 2018. The adherence to the MedDiet was measured by the relative Mediterranean score (rMED) and categorized as high, medium and low. Time-to-death (all-causes) as estimated by average treatment effect on the treated (ATET), potential outcome mean (POM) and relative efficiency of exposure were the outcomes.Results: A total of 4896 subjects were included. The median follow-up time was 12.82 (inter quartile range (IQR) 12.22-13.05), 12.91 (IQR 12.21-13.27) and 12.84 (IQR 12.19-13.03) years for high, medium and low rMED subjects respectively. By December 2018, 453 (9.25%) had died. There was a strong effect of medium and low rMED {ATET, -5.10 [95% confidence interval (CI) -9.39, -0.80] and -8.91 (95%CI -13.37, -4.45), respectively}. High rMED has an important effect on mean age at death [POM 90.16 (95% CI 86.06, 94.25)]. The relative effect size for medium and low rMED subjects was a lower lifespan of 5.62% (95% CI 1.01, 10.3) and 9.90% (95% CI 5.30, 5.30), respectively.Conclusions: We observed an important benefit in additional years of survival from adherence to MedDiet in this southern Italian cohort. Further investigation corroborating our findings in other population groups in other geographic regions will be an important contribution to promoting health and longevity. [ABSTRACT FROM AUTHOR]

Published
2021
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22. Menopause Does Not Affect Fatty Liver Severity In Women: A Population Study in a Mediterranean Area

Author

Veronese, Nicola, primary, Notarnicola, Maria, additional, Osella, Alberto Ruben, additional, Cisternino, Anna Maria, additional, Reddavide, Rosa, additional, Inguaggiato, Rosa, additional, Guerra, Vito, additional, Rotolo, Ornella, additional, Zinzi, Iris, additional, Chiloiro, Marisa, additional, Leandro, Gioacchino, additional, Correale, Mario, additional, Tutino, Valeria, additional, Misciagna, Giovanni, additional, Bonfiglio, Caterina, additional, and Caruso, Maria Gabriella, additional

Published
2018
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24. Selecting the best machine learning algorithm to support the diagnosis of Non-Alcoholic Fatty Liver Disease: A meta learner study.

Author

Sorino, Paolo, Caruso, Maria Gabriella, Misciagna, Giovanni, Bonfiglio, Caterina, Campanella, Angelo, Mirizzi, Antonella, Franco, Isabella, Bianco, Antonella, Buongiorno, Claudia, Liuzzi, Rosalba, Cisternino, Anna Maria, Notarnicola, Maria, Chiloiro, Marisa, Pascoschi, Giovanni, and Osella, Alberto Rubén

Subjects
FATTY liver, MACHINE learning, ALGORITHMS
Abstract

Background & aims Liver ultrasound scan (US) use in diagnosing Non-Alcoholic Fatty Liver Disease (NAFLD) causes costs and waiting lists overloads. We aimed to compare various Machine learning algorithms with a Meta learner approach to find the best of these as a predictor of NAFLD. Methods The study included 2970 subjects, 2920 constituting the training set and 50, randomly selected, used in the test phase, performing cross-validation. The best predictors were combined to create three models: 1) FLI plus GLUCOSE plus SEX plus AGE, 2) AVI plus GLUCOSE plus GGT plus SEX plus AGE, 3) BRI plus GLUCOSE plus GGT plus SEX plus AGE. Eight machine learning algorithms were trained with the predictors of each of the three models created. For these algorithms, the percent accuracy, variance and percent weight were compared. Results The SVM algorithm performed better with all models. Model 1 had 68% accuracy, with 1% variance and an algorithm weight of 27.35; Model 2 had 68% accuracy, with 1% variance and an algorithm weight of 33.62 and Model 3 had 77% accuracy, with 1% variance and an algorithm weight of 34.70. Model 2 was the most performing, composed of AVI plus GLUCOSE plus GGT plus SEX plus AGE, despite a lower percentage of accuracy. Conclusion A Machine Learning approach can support NAFLD diagnosis and reduce health costs. The SVM algorithm is easy to apply and the necessary parameters are easily retrieved in databases. [ABSTRACT FROM AUTHOR]

Published
2020
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27. Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline

Author

Tortelli, Rosanna, primary, Lozupone, Madia, additional, Guerra, Vito, additional, Barulli, Maria Rosaria, additional, Imbimbo, Bruno P., additional, Capozzo, Rosa, additional, Grasso, Alessandra, additional, Tursi, Marianna, additional, Di Dio, Cristina, additional, Sardone, Rodolfo, additional, Giannelli, Gianluigi, additional, Seripa, Davide, additional, Misciagna, Giovanni, additional, Panza, Francesco, additional, and Logroscino, Giancarlo, additional

Published
2017
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28. Diagnostic accuracy of a noninvasive hepatic ultrasound score for non-alcoholic fatty liver disease (NAFLD) in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Author

Goulart, Alessandra Carvalho, Oliveira, Ilka Regina Souza de, Alencar, Airlane Pereira, Santos, Maira Solange Camara dos, Santos, Itamar Souza, Martines, Brenda Margatho Ramos, Meireles, Danilo Peron, Martines, João Augusto dos Santos, Misciagna, Giovanni, Benseñor, Isabela Martins, and Lotufo, Paulo Andrade

Subjects
Hepatopatias, Tomografia computadorizada por raios X, Epidemiology, Ultrassonografia, Diagnostic techniques and procedures, Tomography, x-ray computed, Epidemiologia, Técnicas e procedimentos diagnósticos, Liver disease, Ultrasonography
Abstract

CONTEXT AND OBJECTIVE: Noninvasive strategies for evaluating non-alcoholic fatty liver disease (NAFLD) have been investigated over the last few decades. Our aim was to evaluate the diagnostic accuracy of a new hepatic ultrasound score for NAFLD in the ELSA-Brasil study. DESIGN AND SETTINGS: Diagnostic accuracy study conducted in the ELSA center, in the hospital of a public university. METHODS: Among the 15,105 participants of the ELSA study who were evaluated for NAFLD, 195 individuals were included in this sub-study. Hepatic ultrasound was performed (deep beam attenuation, hepatorenal index and anteroposterior diameter of the right hepatic lobe) and compared with the hepatic steatosis findings from 64-channel high-resolution computed tomography (CT). We also evaluated two clinical indices relating to NAFLD: the fatty liver index (FLI) and the hepatic steatosis index (HSI). RESULTS: Among the 195 participants, the NAFLD frequency was 34.4%. High body mass index, high waist circumference, diabetes and hypertriglyceridemia were associated with high hepatic attenuation and large anteroposterior diameter of the right hepatic lobe, but not with the hepatorenal index. The hepatic ultrasound score, based on hepatic attenuation and the anteroposterior diameter of the right hepatic lobe, presented the best performance for NAFLD screening at the cutoff point ≥ 1 point; sensitivity: 85.1%; specificity: 73.4%; accuracy: 79.3%; and area under the curve (AUC 0.85; 95% confidence interval, CI: 0.78-0.91)]. FLI and HSI presented lower performance (AUC 0.76; 95% CI: 0.69-0.83) than CT. CONCLUSION: The hepatic ultrasound score based on hepatic attenuation and the anteroposterior diameter of the right hepatic lobe has good reproducibility and accuracy for NAFLD screening. CONTEXTO E OBJETIVO: Estratégias não invasivas para avaliar doença hepática gordurosa não alcoólica (DHGNA) têm sido investigadas nas últimas décadas. Nosso objetivo foi avaliar a acurácia diagnóstica de um novo escore de ultrassonografia hepática para DHGNA no estudo ELSA-Brasil. TIPO DE ESTUDO E LOCAL: Estudo de acurácia diagnóstica realizado no centro ELSA, no hospital de uma universidade pública. MÉTODOS: Dos 15.105 participantes do estudo ELSA avaliados para DHGNA, 195 indivíduos foram incluídos neste estudo. Foi realizada ultrassonografia hepática (atenuação do feixe de profundidade, índice hepatorrenal e diâmetro anteroposterior do lobo direito do fígado) que foi comparada aos achados de esteatose hepática da tomografia computadorizada (TC) de alta resolução de 64 canais. Avaliamos também dois índices clínicos relacionados à DHGNA: o índice de gordura hepática (FLI) e o índice de esteatose hepática (HSI). RESULTADOS: Entre os 195 participantes, a frequência de DHGNA foi de 34,4%. Altos índices de massa corpórea, circunferência de cintura, diabetes e hipertrigliceridemia foram associados a aumento da atenuação hepática e do diâmetro anteroposterior do lobo hepático direito, mas não ao índice hepato-renal. A pontuação da ultrassonografia hepática, que incluiu atenuação hepática e diâmetro anteroposterior do lobo direito do fígado, apresentou o melhor desempenho para o rastreio DHGNA sob o ponto de corte ≥ 1 ponto (sensibilidade: 85.1%; especificidade: 73.4%; acurácia: 79.3%), e área sob a curva (AUC, 0,85, IC 95%: 0,78-0,91). FLI e HSI apresentaram menor desempenho (AUC 0,76; IC 95%: 0,69-0,83) comparados à TC. CONCLUSÃO: O escore de ultrassonografia hepática, que incluiu atenuação hepática e o diâmetro anteroposterior do lobo direito do fígado, possui boa reprodutibilidade e acurácia para o rastreio de DHGNA.

Published
2015

29. Coffee Consumption Habits and the Risk of Mild Cognitive Impairment: The Italian Longitudinal Study on Aging

Author

Solfrizzi, Vincenzo, Panza, Francesco, Imbimbo, Bruno P, D'Introno, Alessia, Galluzzo, Lucia, Gandin, Claudia, Misciagna, Giovanni, Guerra, Vito, Osella, Alberto, Baldereschi, Marzia, Di Carlo, Antonio, Inzitari, Domenico, Seripa, Davide, Pilotto, Alberto, Sabbá, Carlo, Logroscino, Giancarlo, Scafato, Emanuele, for the ILSA Working group, and Sergi, Giuseppe

Subjects
Gerontology, Risk, Longitudinal study, Aging, Population, Neuropsychological Tests, Coffee, chemistry.chemical_compound, mild cognitive impairment, Sex Factors, Caffeine, medicine, 80 and over, Dementia, Humans, Cognitive Dysfunction, Women, Longitudinal Studies, education, Depression (differential diagnoses), Aged, Aged, 80 and over, coffee consumption, education.field_of_study, Tea, Depression, General Neuroscience, Incidence (epidemiology), Hazard ratio, caffeine use, Men, General Medicine, Feeding Behavior, medicine.disease, Confidence interval, Psychiatry and Mental health, Clinical Psychology, chemistry, Italy, Alzheimer’s disease, dementia, Follow-Up Studies, Geriatrics and Gerontology, Psychology, Demography
Abstract

Coffee, tea, or caffeine consumption may be protective against cognitive impairment and dementia. We estimated the association between change or constant habits in coffee consumption and the incidence of mild cognitive impairment (MCI). We evaluated 1,445 individuals recruited from 5,632 subjects, aged 65-84 year old, from the Italian Longitudinal Study on Aging, a population-based sample from eight Italian municipalities with a 3.5-year median follow-up. Cognitively normal older individuals who habitually consumed moderate amount of coffee (from 1 to 2 cups of coffee/day) had a lower rate of the incidence of MCI than those who never or rarely consumed coffee [1 cup/day: hazard ratio (HR): 0.47, 95% confidence interval (CI): 0.211 to 1.02 or 1-2 cups/day: HR: 0.31 95% CI: 0.13 to 0.75]. For cognitively normal older subjects who changed their coffee consumption habits, those increasing coffee consumption (1 cup of coffee/day) had higher rate of the incidence of MCI compared to those with constant habits (up to ±1 cup of coffee/day) (HR: 1.80, 95% CI: 1.11 to 2.92) or those with reduced consumption (1 cup of coffee/day) (HR: 2.17, 95% CI: 1.16 to 4.08). Finally, there was no significant association between subjects with higher levels of coffee consumption (2 cups of coffee/day) and the incidence of MCI in comparison with those who never or rarely consumed coffee (HR: 0.26, 95% CI: 0.03 to 2.11). In conclusion, cognitively normal older individuals who increased their coffee consumption had a higher rate of developing MCI, while a constant in time moderate coffee consumption was associated to a reduced rate of the incidence of MCI.

Published
2015

30. Reducing NAFLD‐screening time: A comparative study of eight diagnostic methods offering an alternative to ultrasound scans.

Author

Procino, Filippo, Misciagna, Giovanni, Veronese, Nicola, Caruso, Maria G., Chiloiro, Marisa, Cisternino, Anna M., Notarnicola, Maria, Bonfiglio, Caterina, Bruno, Irene, Buongiorno, Claudia, Campanella, Angelo, Deflorio, Valentina, Franco, Isabella, Guerra, Rocco, Leone, Carla M., Mirizzi, Antonella, Nitti, Alessandro, and Osella, Alberto R.

Subjects
*ULTRASONIC imaging, *FATTY liver, *FATTY degeneration, *DIAGNOSIS, *LIVER diseases
Abstract

Background & Aims: The use of ultrasound scan (US) in non‐alcoholic fatty liver disease (NAFLD) screening overloads US waiting lists. We hypothesized and tested a hybrid two‐step method, consisting of applying a formula, to exclude subjects at low risk, before US. Methods: The sample included 2970 males and females (937 with NAFLD) diagnosed by US. We selected eight formulas: Fatty Liver Index (FLI), Hepatic Steatosis Index (HIS), body mass index (BMI), waist circumference (WC), Abdominal Volume Index (AVI), waist‐to‐height ratio (WHtR), waist/height0.5 (WHT.5R) and Body Roundness Index (BRI), and calculated their performance in the two‐step method evaluating percentage reduction of the number of liver US (US reduction percentage), percentage of false negative and percentage of NAFLD identified. Results: The US reductions percentage were 52.2% (WHtR), 52.1% (HIS), 51.8% (FLI), 50.8% (BRI), 50.7% (BMI and WHt_5R), 46.5% (WC) and 45.2% (AVI). The false negative percentage were 8.5% (WHtR), 7.9% (BRI), 7.3% (WHt_5R), 7.2% (BMI), 6.7% (HIS), 6.6% (FLI), 5.6% (WC) and 5.2% (AVI). The best percentage of NALFD identified was obtained using AVI (83.6%) before US, then WC (82.2%), FLI (79%), HIS (78.9%), BMI (77.3%), WHt_5R (76.9%), BRI (74.8%) and WHtR (73%). Conclusion: The best formula to use in two‐step diagnostic NAFLD screening was AVI, which showed a low false negative rate and a higher percentage of identified NAFLD. Other studies evaluating the economic advantages of this screening method are warranted. [ABSTRACT FROM AUTHOR]

Published
2019
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31. Hepatitis C Virus Genotypes and Risk of Cirrhosis in Southern Italy

Author

Osella, Alberto R., Misciagna, Giovanni, Guerra, Vito, Elba, Silvana, Buongiorno, Giampiero, Cavallini, Aldo, Leo, Alfredo Di, Sonzogni, Laura, Mondelli, Mario U., and Silini, Enrico M.

Subjects
Hepatitis C virus -- Health aspects, Liver cirrhosis -- Causes of, Health, Health care industry
Published
2001

32. Coffee Intake and Liver Steatosis: A Population Study in a Mediterranean Area.

Author

Veronese, Nicola, Notarnicola, Maria, Cisternino, Anna Maria, Reddavide, Rosa, Inguaggiato, Rosa, Guerra, Vito, Rotolo, Ornella, Zinzi, Iris, Leandro, Gioacchino, Correale, Mario, Tutino, Valeria, Misciagna, Giovanni, Osella, Alberto Ruben, Bonfiglio, Caterina, Giannelli, Gianluigi, and Caruso, Maria Gabriella

Abstract

Coffee drinking seems to have several beneficial effects on health outcomes. However, the effect on hepatic steatosis, depending on a high alcohol consumption (AFLD, alcoholic fatty liver disease) or on metabolic factors (non-alcoholic fatty liver disease, NAFLD), is still equivocal. Thus, we aimed to explore the potential association between coffee consumption and the presence and severity of hepatic steatosis in people with NAFLD or AFLD. In this cross-sectional study, coffee drinking was recorded using a semi-quantitative food frequency questionnaire, and categorized as yes vs. no and as 0, 1, 2, ≥3. The degree of fatty liver was assessed through a standardized ultrasound examination (score 0 to 6, with higher values reflecting higher severity). Liver steatosis was classified as NAFLD or AFLD on daily alcohol intake >30 g/day for men and >20 g/day for women. This study included 2819 middle-aged participants; the great majority were coffee drinkers (86.1%). After adjusting for 12 potential confounders, drinking coffee was not associated with decreased odds for NAFLD (n = 916) (odds ratio, OR = 0.93; 95% confidence intervals, CI: 0.72-1.20) or AFLD (n = 276) (OR = 1.20; 95% CI: 0.66-2.0). The consumption of coffee (categorized as yes vs. no), or an increased consumption of coffee were not associated with the presence of mild, moderate or severe liver steatosis in either NAFLD or AFLD. In conclusion, coffee intake was not associated with any lower odds of hepatic steatosis in either non-alcoholic or alcoholic forms in this large cohort of South Italian individuals. [ABSTRACT FROM AUTHOR]

Published
2018
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33. Diagnostic accuracy of a noninvasive hepatic ultrasound score for non-alcoholic fatty liver disease (NAFLD) in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Author

Goulart, Alessandra Carvalho, primary, Oliveira, Ilka Regina Souza de, additional, Alencar, Airlane Pereira, additional, Santos, Maira Solange Camara dos, additional, Santos, Itamar Souza, additional, Martines, Brenda Margatho Ramos, additional, Meireles, Danilo Peron, additional, Martines, João Augusto dos Santos, additional, Misciagna, Giovanni, additional, Benseñor, Isabela Martins, additional, and Lotufo, Paulo Andrade, additional

Published
2015
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34. Ultrasound Evaluation and Correlates of Fatty Liver Disease: A Population Study in a Mediterranean Area

Author

Chiloiro, Marisa, primary, Caruso, Maria Gabriella, additional, Cisternino, Anna Maria, additional, Inguaggiato, Rosa, additional, Reddavide, Rosa, additional, Bonfiglio, Caterina, additional, Guerra, Vito, additional, Notarnicola, Maria, additional, De Michele, Giampietro, additional, Correale, Mario, additional, Noviello, Maria Rosaria, additional, and Misciagna, Giovanni, additional

Published
2013
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38. Diagnostic accuracy of a noninvasive hepatic ultrasound score for non-alcoholic fatty liver disease (NAFLD) in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Author

Carvalho Goulart, Alessandra, de Oliveira, Ilka Regina Souza, Pereira Alencar, Airlane, dos Santos, Maira Solange Camara, Souza Santos, Itamar, Ramos Martines, Brenda Margatho, Peron Meireles, Danilo, dos Santos Martines, João Augusto, Misciagna, Giovanni, Martins Benseñor, Isabela, and Andrade Lotufo, Paulo

Published
2015
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45. Epidemiology of cholelithiasis in southern Italy. Part II

Author

Misciagna, Giovanni, primary, Leoci, Claudio, additional, Guerra, Vito, additional, Chiloiro, Marisa, additional, Elba, Silvana, additional, Petruzzi, José, additional, Mossa, Ascanio, additional, Noviello, Maria R., additional, Coviello, Angelo, additional, Minutolo, Marino Capece, additional, Mangini, Vito, additional, Messa, Caterina, additional, Cavallini, Aldo, additional, Michele, Giampiero De, additional, and Giorgio, Italo, additional

Published
1996
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46. Incidence and Risk Factors of Duodenal Ulcer

Author

Leoci, Claudio, primary, Ierardi, Enzo, additional, Chiloiro, Marisa, additional, Piccioli, Elettra, additional, Matteo, Giovanni Di, additional, Misciagna, Giovanni, additional, and Giorgio, Italo, additional

Published
1995
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47. The epidemiology of cholelithiasis in southern Italy

Author

Misciagna, Giovanni, primary, Leoci, Claudio, additional, Elba, Silvana, additional, Petruzzi, Jose, additional, Guerra, Vito, additional, Mossa, Ascanio, additional, Noviello, Maria Rosaria, additional, Coviello, Angelo, additional, Capece-Minutolo, Marino, additional, and Giorgiot, Italo, additional

Published
1994
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50. Prevalence of pigment gallstones in sheep

Author

Cavallini, Aldo, primary, Messa, Caterina, additional, Mangini, Vito, additional, Linsalata, Michele, additional, Guerra, Vito, additional, Misciagna, Giovanni, additional, and Di Leo, Alfredo, additional

Published
1991
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