1. Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient
- Author
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Sungjin Park, Madoka Suzuki, Young-Tae Chang, Jung Sun Yoo, Satoshi Arai, Hyung-Ho Ha, Lu Wang, and Nam-Young Kang
- Subjects
Thermometry ,Catalysis ,Fluorescence ,Cell Line ,Mice ,Materials Chemistry ,Animals ,Humans ,Fluorescent Dyes ,Molecular Structure ,Chemistry ,Mito thermo yellow ,Metals and Alloys ,Microscopic level ,Temperature ,General Chemistry ,3T3 Cells ,Small molecule ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Mitochondria ,Temperature gradient ,Biochemistry ,Xanthenes ,Thermometer ,Ceramics and Composites ,Biophysics ,Intracellular ,Mitochondria targeted ,HeLa Cells - Abstract
Intracellular thermometry at the microscopic level is currently a hot topic. Herein we describe a small molecule fluorescent thermometer targeting mitochondria (Mito thermo yellow). Mito thermo yellow successfully demonstrates the ability to monitor the intracellular temperature gradient, generated by exogenous heating, in various cells.
- Published
- 2015