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141 results on '"Mitsutake, Y"'

4. Trial Design Principles for Patients at High Bleeding Risk Undergoing PCI: JACC Scientific Expert Panel

Author

Capodanno, D, Morice, MC, Angiolillo, DJ, Bhatt, DL, Byrne, RA, Colleran, R, Cuisset, T, Cutlip, D, Eerdmans, P, Eikelboom, J, Farb, A, Gibson, C M, Gregson, J, Haude, M, James, SK, Kim, HS, Kimura, T, Konishi, A, Leon, MB, Magee, PFA, Mitsutake, Y, Mylotte, Darren, Pocock, SJ, Rao, SV, Spitzer, Ernest, Stockbridge, N, Valgimigli, M, Varenne, O, Windhovel, U, Krucoff, MW, Urban, P, Mehran, R, and Cardiology

Subjects
Clinical Trials as Topic, Percutaneous Coronary Intervention, Outcome Assessment, Health Care, high bleeding risk, trial design, Humans, Hemorrhage
Abstract

Investigating the balance of risk for thrombotic and bleeding events after percutaneous coronary intervention (PCI) is especially relevant for patients at high bleeding risk (HBR). The Academic Research Consortium for HBR recently proposed a consensus definition in an effort to standardize the patient population included in HBR trials. The aim of this consensus-based document, the second initiative from the Academic Research Consortium for HBR, is to propose recommendations to guide the design of clinical trials of devices and drugs in HBR patients undergoing PCI. The authors discuss the designs of trials in HBR patients undergoing PCI and various aspects of trial design specific to HBR patients, including target populations, intervention and control groups, primary and secondary outcomes, and timing of endpoint reporting.

Published
2020

9. Shape of an annular liquid jet

Author

Hasan, M.Z., Mitsutake, Y., and Monde, M.

Subjects
Fluid dynamics -- Research, Jets -- Fluid dynamics, Engineering and manufacturing industries, Science and technology
Published
1997

10. Dynamic response analysis of a linear solenoid actuator

Author

Mitsutake, Y., Hirata, K., and Ishihara, Y.

Subjects
Solenoids -- Research, Actuators -- Research, Business, Electronics, Electronics and electrical industries
Abstract

This paper proposes a computational method for predicting the dynamic response characteristics of a long stroke-linear solenoid actuator with complicated shaped armature. In this method, the magnetic field is coupled with the electrical supply and the mechanical movement of the actuator, employing the axisymmetric finite element method (FEM). The influence of applied voltage on the response characteristics are investigated. As the result of that, computational error of 22.8% arises when applied voltage of 4.8V is fed, however, the error remains less than 2% when the applied voltage is higher; 5.8V and 6.8V. These results verify the utility of this method. In addition, the influence of the control method on transient response during positioning control is also examined, and the validity of PID (proportional, integral and differential) control is confirmed.

Published
1997

11. Defining high bleeding risk in patients undergoing percutaneous coronary intervention: a consensus document from the Academic Research Consortium for High Bleeding Risk

Author

Urban, P. (Philip), Mehran, R. (Roxana), Colleran, R., Angiolillo, D.J. (Dominick), Byrne, R.A. (Robert), Capodanno, D. (Davide), Cuisset, T, Cutlip, D., Eerdmans, P. (Pedro), Eikelboom, J., Farb, A. (Andrew), Gibson, C. M., Gregson, J, Haude, M. (Michael), James, S.K. (Stefan), Kim, H-S. (Hyo-Soo), Kimura, T. (Takeshi), Konishi, A., Laschinger, J., Leon, M.B. (Martin), Magee, P.A., Mitsutake, Y., Mylotte, D.M. (Darren), Ls, S.P., Price, MJ, Rao, SV, Spitzer, E, Stockbridge, N., Valgimigli, M. (Marco), Varenne, O. (Olivier), Windhoevel, U., Yeh, R.W., Krucoff, M. (Mitchell), Morice, M-C. (Marie-Claude), Urban, P. (Philip), Mehran, R. (Roxana), Colleran, R., Angiolillo, D.J. (Dominick), Byrne, R.A. (Robert), Capodanno, D. (Davide), Cuisset, T, Cutlip, D., Eerdmans, P. (Pedro), Eikelboom, J., Farb, A. (Andrew), Gibson, C. M., Gregson, J, Haude, M. (Michael), James, S.K. (Stefan), Kim, H-S. (Hyo-Soo), Kimura, T. (Takeshi), Konishi, A., Laschinger, J., Leon, M.B. (Martin), Magee, P.A., Mitsutake, Y., Mylotte, D.M. (Darren), Ls, S.P., Price, MJ, Rao, SV, Spitzer, E, Stockbridge, N., Valgimigli, M. (Marco), Varenne, O. (Olivier), Windhoevel, U., Yeh, R.W., Krucoff, M. (Mitchell), and Morice, M-C. (Marie-Claude)

Abstract

Identification and management of patients at high bleeding risk undergoing percutaneous coronary intervention are of major importance, but a lack of standardization in defining this population limits trial design, data interpretation, and clinical decision-making. The Academic Research Consortium for High Bleeding Risk (ARC-HBR) is a collaboration among leading research organizations, regulatory authorities, and physician-scientists from the United States, Asia, and Europe focusing on percutaneous coronary intervention–related bleeding. Two meetings of the 31-member consortium were held in Washington, DC, in April 2018 and in Paris, France, in October 2018. These meetings were organized by the Cardiovascular European Research Center on behalf of the ARC-HBR group and included representatives of the US Food and Drug Administration and the Japanese Pharmaceuticals and Medical Devices Agency, as well as observers from the pharmaceutical and medical device industries. A consensus definition of patients at high bleeding risk was developed that was based on review of the available evidence. The definition is intended to provide consistency in defining this population for clinical trials and to complement clinical decision-making and regulatory review. The proposed ARC-HBR consensus document represents the first pragmatic approach to a consistent definition of high bleeding risk in clinical trials evaluating the safety and effectiveness of devices and drug regimens for patients undergoing percutaneous coronary intervention.

Published
2019
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12. Defining high bleeding risk in patients undergoing percutaneous coronary intervention: a consensus document from the Academic Research Consortium for High Bleeding Risk

Author

Urban, P, Mehran, R, Colleran, R, Angiolillo, DJ, Byrne, RA, Capodanno, D, Cuisset, T, Cutlip, D, Eerdmans, P, Eikelboom, J, Farb, A, Gibson, C M, Gregson, J, Haude, M, James, SK, Kim, HS, Kimura, T, Konishi, A, Laschinger, J, Leon, MB, Magee, PA, Mitsutake, Y, Mylotte, Darren, Ls, SP, Price, MJ, Rao, SV, Spitzer, Ernest, Stockbridge, N, Valgimigli, M (Marco), Varenne, O, Windhoevel, U, Yeh, RW, Krucoff, MW, Morice, MC, Urban, P, Mehran, R, Colleran, R, Angiolillo, DJ, Byrne, RA, Capodanno, D, Cuisset, T, Cutlip, D, Eerdmans, P, Eikelboom, J, Farb, A, Gibson, C M, Gregson, J, Haude, M, James, SK, Kim, HS, Kimura, T, Konishi, A, Laschinger, J, Leon, MB, Magee, PA, Mitsutake, Y, Mylotte, Darren, Ls, SP, Price, MJ, Rao, SV, Spitzer, Ernest, Stockbridge, N, Valgimigli, M (Marco), Varenne, O, Windhoevel, U, Yeh, RW, Krucoff, MW, and Morice, MC

Published
2019

13. Numerical method for the performance of a separate-type transformer connected to a battery charger

Author

Hirata, K., Mitsutake, Y., Ishihara, Y., and Todaka, T.

Subjects
Electric transformers -- Models, Magnetic fields -- Models, Business, Electronics, Electronics and electrical industries
Abstract

The purpose of this paper is to present an easy method for analyzing the operating characteristics of a separate-type transformer connected to an external circuit including elements such as batteries, resistances, and diodes. This method, a combination of two- and three-dimensional finite element methods, has been applied to a transformer connected to a compact battery charger to obtain its output characteristics. The utility of this method has been verified by comparing the measured results.

Published
1995

14. Critical heat flux in forced convective subcooled boiling with multiple impinging jets

Author

Monde, M. and Mitsutake, Y.

Subjects
Heat -- Convection, Mass transfer -- Measurement, Thermodynamics -- Measurement, Engineering and manufacturing industries, Science and technology
Abstract

Experiments are performed to measure the critical heat flux (CHF) in forced convective subcooled boiling with multiple impinging jets. The jet velocity, liquid temperature and system pressure are strictly regulated throughout the study while the electric power for heating is increased gradually. Results show that the properties of the CHF for both the single and multiple jets are very similar.

Published
1996

16. Critical heat flux during natural circulation boiling of saturated liquid in annulus with uniformly heated outer tube

Author

Monde, M. and Mitsutake, Y.

Subjects
Steel tubes -- Thermal properties, Water -- Thermal properties, Engineering and manufacturing industries, Science and technology
Abstract

The critical heat flux during the natural circulation boiling of water and R113 is measured on a uniformly heated outer tube in a vertical annular tube. Based on the characteristics of the heated equivalent diameter the similarity of critical heat flux between annular configurations of either inner or outer heated tubes and a simple heated tube can be clearly elucidated.

Published
2000

21. Analysis of Viscous Micropump with Single Rotating Cylinder.

Author

Mondal, Md. Nur Alam, Islam, Md. Shafiqul, Hasan, A. B. M. Toufique, and Mitsutake, Y.

Subjects
VISCOSITY, MICROPUMPS, ROTATIONAL motion, REYNOLDS number, NAVIER-Stokes equations
Abstract

This study presents the transient nature and performance of viscous micropump for low Reynolds number where flow is assumed laminar, unsteady, incompressible and two dimensional. The device consists of a cylinder placed eccentrically inside an extremely narrow channel, where channel axis is perpendicular to cylinder axis. When the cylinder rotates, it generates a net force on fluid due to unequal shear stresses on the top and bottom surfaces of the cylinder. This net force is capable of generating a net flow against a pressure gradient. The flow field inside the micro channel has been analyzed by using structured grid Finite Volume Method (FVM) based on Navier-Stokes equation. All parameters used in flow simulation are expressed in non-dimensional quantities for better understanding of flow behavior, regardless of dimensions or the fluid that is used. The effect of the channel height (S), the cylinder eccentricity (ε), the Reynolds number (Re) and Pump load (P*) have been studied. Various flow patterns inside the micro pump as well as variations in flow velocity with time are obtained. Both the steady state and transient results of viscous micro pump are validated. It is found that the average velocity of fluid increases with increasing cylinder eccentricity and decreases with increasing the channel height. [ABSTRACT FROM AUTHOR]

Published
2016
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22. Effect of Cavity on Shock Oscillation in Transonic Flow over RAE2822 Supercritical Airfoil.

Author

Rahman, M. Rizwanur, Labib, Md. Itmam, Hasan, A. B. M. Toufique, Ali, M., Mitsutake, Y., and Setoguchi, T.

Subjects
SHOCK waves, SUPERCRITICAL fluids, AEROFOILS, TRANSONIC flow, REYNOLDS number, NAVIER-Stokes equations
Abstract

Transonic flow past a supercritical airfoil is strongly influenced by the interaction of shock wave with boundary layer. This interaction induces unsteady self-sustaining shock wave oscillation, flow instability, drag rise and buffet onset which limit the flight envelop. In the present study, a computational analysis has been carried out to investigate the flow past a supercritical RAE2822 airfoil in transonic speeds. To control the shock wave oscillation, a cavity is introduced on the airfoil surface where shock wave oscillates. Different geometric configurations have been investigated for finding optimum cavity geometry and dimension. Unsteady Reynolds averaged Navier-Stokes equations (RANS) are computed at Mach 0.729 with an angle of attack of 5°. Computed results are well validated with the available experimental data in case of baseline airfoil. However, in case of airfoil with control cavity; it has been observed that the introduction of cavity completely suppresses the unsteady shock wave oscillation. Further, significant drag reduction and successive improvement of aerodynamic performance have been observed in airfoil with shock control cavity. [ABSTRACT FROM AUTHOR]

Published
2016
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23. A Computational Study on Oblique Shock Wave-Turbulent Boundary Layer Interaction.

Author

Joy, Md. Saddam Hossain, Rahman, Saeedur, Hasan, A. B. M. Toufique, Ali, M., Mitsutake, Y., Matsuo, S., and Setoguchi, T.

Subjects
SHOCK waves, TURBULENCE, BOUNDARY layer (Aerodynamics), THEORY of wave motion, LARGE eddy simulation models
Abstract

A numerical computation of an oblique shock wave incident on a turbulent boundary layer was performed for free stream flow of air at M∞ = 2.0 and Re1= 10.5×106 m-1. The oblique shock wave was generated from a 8° wedge. Reynolds averaged Navier-Stokes (RANS) simulation with k-ω SST turbulence model was first utilized for two dimensional (2D) steady case. The results were compared with the experiment at the same flow conditions. Further, to capture the unsteadiness, a 2D Large Eddy Simulation (LES) with sub-grid scale model WMLES was performed which showed the unsteady effects. The frequency of the shock oscillation was computed and was found to be comparable with that of experimental measurement. [ABSTRACT FROM AUTHOR]

Published
2016
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