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Your search keyword '"Mize, Gregory J."' showing total 25 results
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25 results on '"Mize, Gregory J."'

7. Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

Author

Astronomo, Rena D., primary, Santra, Sampa, additional, Ballweber-Fleming, Lamar, additional, Westerberg, Katharine G., additional, Mach, Linh, additional, Hensley-McBain, Tiffany, additional, Sutherland, Laura, additional, Mildenberg, Benjamin, additional, Morton, Georgeanna, additional, Yates, Nicole L., additional, Mize, Gregory J., additional, Pollara, Justin, additional, Hladik, Florian, additional, Ochsenbauer, Christina, additional, Denny, Thomas N., additional, Warrier, Ranjit, additional, Rerks-Ngarm, Supachai, additional, Pitisuttithum, Punnee, additional, Nitayapan, Sorachai, additional, Kaewkungwal, Jaranit, additional, Ferrari, Guido, additional, Shaw, George M., additional, Xia, Shi-Mao, additional, Liao, Hua-Xin, additional, Montefiori, David C., additional, Tomaras, Georgia D., additional, Haynes, Barton F., additional, and McElrath, M. Juliana, additional

Published
2016
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8. Protease-activated receptor mediated RhoA signaling and cytoskeletal reorganization in LNCaP cells

Author

Greenberg, Daniel L., Mize, Gregory J., and Takayama, Thomas K.

Subjects
Prostate cancer -- Physiological aspects, Cytoskeletal proteins -- Physiological aspects, Enzyme activation -- Physiological aspects, Cellular signal transduction -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research demonstrates the expression of the three protease-activated receptors (PARs) in the androgen-dependent LNCaP cells. Selective PAR activation with hexapeptides indicate that PAR1 and 2 mediate RhoA activation in LNCaP cells, which coupled with trypsin and thrombin leads rearrangment of cytoskeletal structures in LNCaP cells.

Published
2003

10. A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity

Author

Pattacini, Laura, primary, Mize, Gregory J., additional, Graham, Jessica B., additional, Fluharty, Tayler R., additional, Graham, Tisha M., additional, Lingnau, Karen, additional, Wizel, Benjamin, additional, Perdiguero, Beatriz, additional, Esteban, Mariano, additional, Pantaleo, Giuseppe, additional, Shen, Mingchao, additional, Spies, Gregory A., additional, McElrath, M. Juliana, additional, and Lund, Jennifer M., additional

Published
2012
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24. In VitroTranslation of the Upstream Open Reading Frame in the Mammalian mRNA EncodingS-Adenosylmethionine Decarboxylase*

Author

Raney, Alexa, Baron, Anita C., Mize, Gregory J., Law, G. Lynn, and Morris, David R.

Abstract

The upstream open reading frame (uORF) in the mRNA encoding S-adenosylmethionine decarboxylase is a polyamine-responsive element that suppresses translation of the associated downstream cistron in vivo. In this paper, we provide the first direct evidence of peptide synthesis from theS-adenosylmethionine decarboxylase uORF using an in vitrotranslation system. We examine both the influence of cation concentration on peptide synthesis and the effect of altering the uORF sequence on peptide synthesis. Synthesis of wild type and altered peptides was similar at all concentrations of magnesium tested. In contrast, synthesis of the wild type peptide was more sensitive than that of altered peptides to elevated concentrations of the naturally occurring polyamines, spermidine and spermine, as well as several polyamine analogs. The sensitivity of in vitrosynthesis to spermidine was influenced by both the amino acid sequence and the length of the peptide product of the uORF. Findings from the present study correlate with the effects of the uORF and polyamines on translation of a downstream cistron in vivoand support the hypothesis that polyamines and the structure of the nascent peptide create a rate-limiting step in uORF translation, perhaps through a ribosome stalling mechanism.

Published
2000
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25. The Two Upstream Open Reading Frames of Oncogene mdm2 Have Different Translational Regulatory Properties.

Author

Xiaoping Jin, Turcott, Eileen, Englehardt, Silvia, Mize, Gregory J., and Morris, David R.

Subjects
*ONCOGENES, *EUKARYOTIC cells
Abstract

Focuses on mechanisms through which multiple upstream open reading frames of oncogenes interact to regulate translation in eukaryotes. Content of the predominant transcript of oncogene in normal human cells; Increase of the translational efficiency of the transcript; Occurrence of secondary structure or rare codons.

Published
2003
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